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Resolving plant development in space and time with single-cell genomics.

Publication ,  Journal Article
Nolan, TM; Shahan, R
Published in: Current opinion in plant biology
December 2023

Single-cell genomics technologies are ushering in a new research era. In this review, we summarize the benefits and current challenges of using these technologies to probe the transcriptional regulation of plant development. In addition to profiling cells at a single snapshot in time, researchers have recently produced time-resolved datasets to map cell responses to stimuli. Live-imaging and spatial transcriptomic techniques are rapidly being adopted to link a cell's transcriptional profile with its spatial location within a tissue. Combining these technologies is a powerful spatiotemporal approach to investigate cell plasticity and developmental responses that contribute to plant resilience. Although there are hurdles to overcome, we conclude by discussing how single-cell genomics is poised to address developmental questions in the coming years.

Duke Scholars

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Published In

Current opinion in plant biology

DOI

EISSN

1879-0356

ISSN

1369-5266

Publication Date

December 2023

Volume

76

Start / End Page

102444

Related Subject Headings

  • Transcriptome
  • Single-Cell Analysis
  • Plant Development
  • Plant Biology & Botany
  • Genomics
  • Gene Expression Profiling
  • 3108 Plant biology
  • 0607 Plant Biology
  • 0605 Microbiology
  • 0601 Biochemistry and Cell Biology
 

Citation

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Nolan, T. M., & Shahan, R. (2023). Resolving plant development in space and time with single-cell genomics. Current Opinion in Plant Biology, 76, 102444. https://doi.org/10.1016/j.pbi.2023.102444
Nolan, Trevor M., and Rachel Shahan. “Resolving plant development in space and time with single-cell genomics.Current Opinion in Plant Biology 76 (December 2023): 102444. https://doi.org/10.1016/j.pbi.2023.102444.
Nolan TM, Shahan R. Resolving plant development in space and time with single-cell genomics. Current opinion in plant biology. 2023 Dec;76:102444.
Nolan, Trevor M., and Rachel Shahan. “Resolving plant development in space and time with single-cell genomics.Current Opinion in Plant Biology, vol. 76, Dec. 2023, p. 102444. Epmc, doi:10.1016/j.pbi.2023.102444.
Nolan TM, Shahan R. Resolving plant development in space and time with single-cell genomics. Current opinion in plant biology. 2023 Dec;76:102444.
Journal cover image

Published In

Current opinion in plant biology

DOI

EISSN

1879-0356

ISSN

1369-5266

Publication Date

December 2023

Volume

76

Start / End Page

102444

Related Subject Headings

  • Transcriptome
  • Single-Cell Analysis
  • Plant Development
  • Plant Biology & Botany
  • Genomics
  • Gene Expression Profiling
  • 3108 Plant biology
  • 0607 Plant Biology
  • 0605 Microbiology
  • 0601 Biochemistry and Cell Biology