
Resolving plant development in space and time with single-cell genomics.
Single-cell genomics technologies are ushering in a new research era. In this review, we summarize the benefits and current challenges of using these technologies to probe the transcriptional regulation of plant development. In addition to profiling cells at a single snapshot in time, researchers have recently produced time-resolved datasets to map cell responses to stimuli. Live-imaging and spatial transcriptomic techniques are rapidly being adopted to link a cell's transcriptional profile with its spatial location within a tissue. Combining these technologies is a powerful spatiotemporal approach to investigate cell plasticity and developmental responses that contribute to plant resilience. Although there are hurdles to overcome, we conclude by discussing how single-cell genomics is poised to address developmental questions in the coming years.
Duke Scholars
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Related Subject Headings
- Transcriptome
- Single-Cell Analysis
- Plant Development
- Plant Biology & Botany
- Genomics
- Gene Expression Profiling
- 3108 Plant biology
- 0607 Plant Biology
- 0605 Microbiology
- 0601 Biochemistry and Cell Biology
Citation

Published In
DOI
EISSN
ISSN
Publication Date
Volume
Start / End Page
Related Subject Headings
- Transcriptome
- Single-Cell Analysis
- Plant Development
- Plant Biology & Botany
- Genomics
- Gene Expression Profiling
- 3108 Plant biology
- 0607 Plant Biology
- 0605 Microbiology
- 0601 Biochemistry and Cell Biology