Scholars@Duke publication: Role of phosphopantetheinyl transferase genes in antibiotic production by Streptomyces coelicolor.

Role of phosphopantetheinyl transferase genes in antibiotic production by Streptomyces coelicolor.

Publication , Journal Article

Lu, Y-W; San Roman, AK; Gehring, AM

Published in: J Bacteriol

October 2008

The phosphopantetheinyl transferase genes SCO5883 (redU) and SCO6673 were disrupted in Streptomyces coelicolor. The redU mutants did not synthesize undecylprodigiosin, while SCO6673 mutants failed to produce calcium-dependent antibiotic. Neither gene was essential for actinorhodin production or morphological development in S. coelicolor, although their mutation could influence these processes.

Duke Scholars

Author Adrianna Katrina San Roman Molecular Genetics and Microbiology

Published In

J Bacteriol

DOI

10.1128/JB.00865-08

EISSN

1098-5530

Publication Date

October 2008

Volume

190

Issue

Start / End Page

6903 / 6908

Location

United States

Related Subject Headings

Transferases (Other Substituted Phosphate Groups)
Streptomyces coelicolor
Prodigiosin
Peptides
Mutagenesis, Insertional
Microbiology
Gene Deletion
Benzoisochromanequinones
Bacterial Proteins
Anti-Bacterial Agents

Citation

APA

Chicago

ICMJE

MLA

NLM

Lu, Y.-W., San Roman, A. K., & Gehring, A. M. (2008). Role of phosphopantetheinyl transferase genes in antibiotic production by Streptomyces coelicolor. J Bacteriol, 190(20), 6903–6908. https://doi.org/10.1128/JB.00865-08

Lu, Ya-Wen, Adrianna K. San Roman, and Amy M. Gehring. “Role of phosphopantetheinyl transferase genes in antibiotic production by Streptomyces coelicolor.” J Bacteriol 190, no. 20 (October 2008): 6903–8. https://doi.org/10.1128/JB.00865-08.

Lu Y-W, San Roman AK, Gehring AM. Role of phosphopantetheinyl transferase genes in antibiotic production by Streptomyces coelicolor. J Bacteriol. 2008 Oct;190(20):6903–8.

Lu, Ya-Wen, et al. “Role of phosphopantetheinyl transferase genes in antibiotic production by Streptomyces coelicolor.” J Bacteriol, vol. 190, no. 20, Oct. 2008, pp. 6903–08. Pubmed, doi:10.1128/JB.00865-08.

Lu Y-W, San Roman AK, Gehring AM. Role of phosphopantetheinyl transferase genes in antibiotic production by Streptomyces coelicolor. J Bacteriol. 2008 Oct;190(20):6903–6908.