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Variations in Managing Acute Spinal Cord Injury in the North American Clinical Trials Network and Partner Institutes.

Journal articles  - Journal Article
Gebeyehu, TF; Sokol, Z; Guest, JD; Harrington, JD; Kabani, AS; Fitchett, E; Lopez, A; Matsoukas, S; Franco, D; Jallo, J; Vaccaro, AR ...
Published in: Global Spine J
January 24, 2026

Study DesignSurvey based study.ObjectivesTo evaluate current patterns for managing SCI among spine surgeons in North America.MethodsA survey of the North American Clinical Trials Network (NACTN) and other institutions collected institutional demographics and specific practices on acute SCI management. Variables included trauma level designation, annual case volumes (patient number, spine fracture and surgery performed), steroid usage, emergent cervical traction, magnetic resonance imaging (MRI) access, surgical decompression timing, intraoperative ultrasound and neuromonitoring use, mean arterial pressure (MAP) and spinal cord perfusion pressure (SCPP) targets, lumbar drain use, and the influence of American Spinal Injury Association (ASIA) Impairment Scale (AIS) grade on decision-making.ResultsThirty surgeons from 23 institutions responded (93.3% Level 1 trauma centers). Most centers (93.3%) had immediate MRI access; about 70% of physicians did not use steroids. Emergent cervical traction was used by 60%. An aim of surgical decompression within 24 h was reported by 90%, with 20% operating immediately upon arrival. MAP goals were used by 93.3%, most targeting 85-90 mmHg for ≥5 days. Lumbar drains for SCPP optimization were used in 30%, typically targeting intrathecal pressure (ITP) < 15 mmHg and SCPP >60 mmHg. Management varied by AIS grade in 43.4%.ConclusionDespite agreement in the general scope of acute SCI care, significant implementation heterogeneity exists across North American spine centers. Variability was pronounced in steroid use, timing of decompression (90% within 24 h), cervical traction, and lumbar drain utilization. These findings call for evidence-based protocols to guide acute SCI management and reduce inter-institutional practice variation.

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Published In

Global Spine J

DOI

ISSN

2192-5682

Publication Date

January 24, 2026

Start / End Page

21925682261421192

Location

England

Related Subject Headings

  • 3202 Clinical sciences
 

Citation

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Gebeyehu, T. F., Sokol, Z., Guest, J. D., Harrington, J. D., Kabani, A. S., Fitchett, E., … Harrop, J. (2026). Variations in Managing Acute Spinal Cord Injury in the North American Clinical Trials Network and Partner Institutes. Global Spine J, 21925682261421190. https://doi.org/10.1177/21925682261421192
Gebeyehu, Teleale Fikru, Zachary Sokol, James D. Guest, Joseph D. Harrington, Ashmal Sami Kabani, Evan Fitchett, Alejandro Lopez, et al. “Variations in Managing Acute Spinal Cord Injury in the North American Clinical Trials Network and Partner Institutes.Global Spine J, January 24, 2026, 21925682261421190. https://doi.org/10.1177/21925682261421192.
Gebeyehu TF, Sokol Z, Guest JD, Harrington JD, Kabani AS, Fitchett E, et al. Variations in Managing Acute Spinal Cord Injury in the North American Clinical Trials Network and Partner Institutes. Global Spine J. 2026 Jan 24;21925682261421190.
Gebeyehu, Teleale Fikru, et al. “Variations in Managing Acute Spinal Cord Injury in the North American Clinical Trials Network and Partner Institutes.Global Spine J, Jan. 2026, p. 21925682261421190. Pubmed, doi:10.1177/21925682261421192.
Gebeyehu TF, Sokol Z, Guest JD, Harrington JD, Kabani AS, Fitchett E, Lopez A, Matsoukas S, Franco D, Jallo J, Vaccaro AR, Abd-El-Barr M, Kurpad SN, Tator CH, Fehlings MG, Harrop J. Variations in Managing Acute Spinal Cord Injury in the North American Clinical Trials Network and Partner Institutes. Global Spine J. 2026 Jan 24;21925682261421190.
Journal cover image

Published In

Global Spine J

DOI

ISSN

2192-5682

Publication Date

January 24, 2026

Start / End Page

21925682261421192

Location

England

Related Subject Headings

  • 3202 Clinical sciences