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Pharmaceutical Sciences Encyclopedia

STRATEGIES FOR THE CYTOSOLIC DELIVERY OF MACROMOLECULES: AN OVERVIEW

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Asokan, A; Cheung, R; Cho, MJ
January 1, 2010

The advent of molecular biology and genetics has identified numerous biotechnology-derived macromolecular drugs as potential targets for development. The delivery of small molecules requires compromise between aqueous solubility and membrane partition properties while that of proteins and genes requires protection from enzymatic degradation and denaturation. This article focuses on strategies to promote the cytosolic delivery of macromolecular therapeutics.

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January 1, 2010

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Asokan, A., Cheung, R., & Cho, M. J. (2010). STRATEGIES FOR THE CYTOSOLIC DELIVERY OF MACROMOLECULES: AN OVERVIEW. In Pharmaceutical Sciences Encyclopedia (pp. 1–18). https://doi.org/10.1002/9780470571224.pse298
Asokan, A., R. Cheung, and M. J. Cho. “STRATEGIES FOR THE CYTOSOLIC DELIVERY OF MACROMOLECULES: AN OVERVIEW.” In Pharmaceutical Sciences Encyclopedia, 1–18, 2010. https://doi.org/10.1002/9780470571224.pse298.
Asokan A, Cheung R, Cho MJ. STRATEGIES FOR THE CYTOSOLIC DELIVERY OF MACROMOLECULES: AN OVERVIEW. In: Pharmaceutical Sciences Encyclopedia. 2010. p. 1–18.
Asokan, A., et al. “STRATEGIES FOR THE CYTOSOLIC DELIVERY OF MACROMOLECULES: AN OVERVIEW.” Pharmaceutical Sciences Encyclopedia, 2010, pp. 1–18. Scopus, doi:10.1002/9780470571224.pse298.
Asokan A, Cheung R, Cho MJ. STRATEGIES FOR THE CYTOSOLIC DELIVERY OF MACROMOLECULES: AN OVERVIEW. Pharmaceutical Sciences Encyclopedia. 2010. p. 1–18.

DOI

Publication Date

January 1, 2010

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1 / 18