Skip to main content

Physical Activity Characteristics and Symptoms of Depression: Findings from the Cooper Center Longitudinal Study.

Journal articles  - Journal Article
Pavlovic, A; Leonard, D; Vukovich, K; Barlow, CE; Shuval, K; Meernik, C; DeFina, LF
Published in: Med Sci Sports Exerc
July 1, 2026

PURPOSE: Examine the relationship between physical activity (PA) characteristics and depressive symptoms among community-dwelling adults. METHODS: The study consisted of 38,946 participants (n = 26,378 men, n = 12,568 women) who completed a 10-item depression screening assessment, the Center for Epidemiologic Studies Depression Scale (CES-D), and reported PA within the prior 3 months as part of a preventive exam. Intensity of PA reported in metabolic equivalent of task (METs) was assigned based on activity using the Compendium of Physical Activities. Weekly PA volume (MET·min per wk) was calculated as the product of product of intensity (METs) and weekly duration (min per wk) summed across reported activities. Leading type (participants' predominant activity) was classified as aerobic, strength, mixed-endurance (e.g., circuit/interval training, basketball, racket sports, etc.), and flexibility. Diversity of activity was calculated based on Shannon's diversity index using binary logarithms on the proportions of time spent in each reported activity. Depressive symptoms were determined by a CES-D score ≥10. Adjusted odds ratios and 95% confidence intervals were estimated using logistic regression to assess the association between PA characteristics and depression symptoms by sex, adjusted for age, current smoking, alcohol intake, body mass index, glucose, cholesterol, and systolic blood pressure. RESULTS: The mean age ± SD for women and men was 48.3 ± 10.8 and 49 ± 10.1 years, respectively. CES-D score ≥10 was present in 15.4% of women and 9.1% of men. Risk of depressive symptoms was inversely related to all PA characteristics individually and to average intensity and diversity of activity when all PA variables were modeled together. CONCLUSIONS: While all measured PA characteristics were associated with reduced odds of depressive symptoms, the most significant associations were observed for PA intensity and diversity. As such, engaging in a variety of activities, some of which are high-intensity, may be associated with lower odds of depressive symptoms.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Med Sci Sports Exerc

DOI

EISSN

1530-0315

Publication Date

July 1, 2026

Volume

58

Issue

7

Start / End Page

1507 / 1514

Location

United States

Related Subject Headings

  • Sport Sciences
  • Middle Aged
  • Male
  • Longitudinal Studies
  • Humans
  • Female
  • Exercise
  • Depression
  • Adult
  • 4207 Sports science and exercise
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Pavlovic, A., Leonard, D., Vukovich, K., Barlow, C. E., Shuval, K., Meernik, C., & DeFina, L. F. (2026). Physical Activity Characteristics and Symptoms of Depression: Findings from the Cooper Center Longitudinal Study. Med Sci Sports Exerc, 58(7), 1507–1514. https://doi.org/10.1249/MSS.0000000000003963
Pavlovic, Andjelka, David Leonard, Katarina Vukovich, Carolyn E. Barlow, Kerem Shuval, Clare Meernik, and Laura F. DeFina. “Physical Activity Characteristics and Symptoms of Depression: Findings from the Cooper Center Longitudinal Study.Med Sci Sports Exerc 58, no. 7 (July 1, 2026): 1507–14. https://doi.org/10.1249/MSS.0000000000003963.
Pavlovic A, Leonard D, Vukovich K, Barlow CE, Shuval K, Meernik C, et al. Physical Activity Characteristics and Symptoms of Depression: Findings from the Cooper Center Longitudinal Study. Med Sci Sports Exerc. 2026 Jul 1;58(7):1507–14.
Pavlovic, Andjelka, et al. “Physical Activity Characteristics and Symptoms of Depression: Findings from the Cooper Center Longitudinal Study.Med Sci Sports Exerc, vol. 58, no. 7, July 2026, pp. 1507–14. Pubmed, doi:10.1249/MSS.0000000000003963.
Pavlovic A, Leonard D, Vukovich K, Barlow CE, Shuval K, Meernik C, DeFina LF. Physical Activity Characteristics and Symptoms of Depression: Findings from the Cooper Center Longitudinal Study. Med Sci Sports Exerc. 2026 Jul 1;58(7):1507–1514.

Published In

Med Sci Sports Exerc

DOI

EISSN

1530-0315

Publication Date

July 1, 2026

Volume

58

Issue

7

Start / End Page

1507 / 1514

Location

United States

Related Subject Headings

  • Sport Sciences
  • Middle Aged
  • Male
  • Longitudinal Studies
  • Humans
  • Female
  • Exercise
  • Depression
  • Adult
  • 4207 Sports science and exercise