Onset of tics in an elderly patient undergoing androgen deprivation therapy for prostate cancer: a case report

Motor and vocal tics typically manifest during childhood. Less often, tics can occur due to the use of substances or medications which raise dopamine levels. This case report describes an unusual occurrence of tics in an elderly man undergoing androgen deprivation with Goserelin for prostate cancer. Comprehensive assessments ruled out infectious, metabolic, psychiatric, and neurological conditions. The tics resolved with low-dose Risperidone, without adverse effects. This case underscores the potential for medication-induced tics in older adults, highlighting the need for increased awareness among healthcare providers regarding the neuropsychiatric effects of cancer therapies. Future research should further investigate these phenomena and their implications for treatment strategies.

Duke Scholars

Author Kim Madundo Duke Global Health Institute