Skip to main content

Prioritizing circulation over airway in trauma patients with exsanguinating injuries: What you need to know.

Journal articles  - Journal Article, Review
Ferrada, P; Duchesne, J; Piehl, M
Published in: J Trauma Acute Care Surg
November 1, 2025

Hemorrhage remains a leading cause of preventable trauma-related mortality, with early resuscitation and hemorrhage control serving as crucial interventions. Emerging evidence suggests that prioritizing circulation before airway (Circulation, Airway, and Breathing [CAB]) during initial resuscitation in patients with exsanguinating injuries can improve survival by avoiding the deleterious effects of postintubation hypotension. This article reviews current evidence supporting the CAB approach and outlines best practices across prehospital, emergency department, and operative settings. Delaying advanced airway management while focusing on immediate hemorrhage control and blood product resuscitation has been associated with decreased 24-hour and 30-day mortality. This review synthesizes findings from recent multicenter trials and literature supporting the CAB paradigm, with practical recommendations for implementation in trauma care systems.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

J Trauma Acute Care Surg

DOI

EISSN

2163-0763

Publication Date

November 1, 2025

Volume

99

Issue

5

Start / End Page

679 / 683

Location

United States

Related Subject Headings

  • Wounds and Injuries
  • Resuscitation
  • Humans
  • Exsanguination
  • Airway Management
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Ferrada, P., Duchesne, J., & Piehl, M. (2025). Prioritizing circulation over airway in trauma patients with exsanguinating injuries: What you need to know. J Trauma Acute Care Surg, 99(5), 679–683. https://doi.org/10.1097/TA.0000000000004618
Ferrada, Paula, Juan Duchesne, and Mark Piehl. “Prioritizing circulation over airway in trauma patients with exsanguinating injuries: What you need to know.J Trauma Acute Care Surg 99, no. 5 (November 1, 2025): 679–83. https://doi.org/10.1097/TA.0000000000004618.
Ferrada P, Duchesne J, Piehl M. Prioritizing circulation over airway in trauma patients with exsanguinating injuries: What you need to know. J Trauma Acute Care Surg. 2025 Nov 1;99(5):679–83.
Ferrada, Paula, et al. “Prioritizing circulation over airway in trauma patients with exsanguinating injuries: What you need to know.J Trauma Acute Care Surg, vol. 99, no. 5, Nov. 2025, pp. 679–83. Pubmed, doi:10.1097/TA.0000000000004618.
Ferrada P, Duchesne J, Piehl M. Prioritizing circulation over airway in trauma patients with exsanguinating injuries: What you need to know. J Trauma Acute Care Surg. 2025 Nov 1;99(5):679–683.

Published In

J Trauma Acute Care Surg

DOI

EISSN

2163-0763

Publication Date

November 1, 2025

Volume

99

Issue

5

Start / End Page

679 / 683

Location

United States

Related Subject Headings

  • Wounds and Injuries
  • Resuscitation
  • Humans
  • Exsanguination
  • Airway Management