An Overview of Management Considerations for Mongolian Gerbils (Meriones unguiculatus), Cats (Felis catus), and Dogs (Canis familiaris) as Hosts for Brugia Infection

Lymphatic filariasis is a mosquito-borne parasitic infection affecting an estimated 51.4 million people. and are used in research because common nonprimate research species such as Mongolian gerbils (), cats (), and dogs () can maintain the life cycle of these species of filarial nematodes. Although overall care and management of animals infected with spp. is relatively straightforward, there are some unique challenges and special considerations that must be addressed when managing a research colony infected with these parasites. In this review, we discuss our experience, share insight into biosafety and clinical management, and describe the expected clinical signs associated with infection in gerbils, cats, and dogs.

Duke Scholars

Author Mary Ann McCrackin Pathology