Ectopic secretion of complete human chorionic gonadotropin and beta-subunit by human cervical carcinoma cells lines.
Journal articles
- Journal Article
Story, MT; Hussa, RO
Published in: J Clin Endocrinol Metab
June 1980
The CaSki and DoT cervical cancer cell lines were reported to secrete the beta-subunit of hCG in the absence of complete hCG or alpha-subunit (Science 196: 1456, 1977; J Clin Endocrinol Metab 46: 69, 1978). In the present study, concentrates of fluids from large numbers of CaSki or DoT cultures were analyzed for the presence of hCG beta and complete hCG. Although some CaSki and DoT preparations contained no detectable complete hCG, others were found to contain as much as 18% hCG. The reason for the variation in the amount of hCG relative to hCG beta in CaSki and DoT cultures is unknown.
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Published In
J Clin Endocrinol Metab
DOI
ISSN
0021-972X
Publication Date
June 1980
Volume
50
Issue
6
Start / End Page
1057 / 1061
Location
United States
Related Subject Headings
- Uterine Cervical Neoplasms
- Radioimmunoassay
- Macromolecular Substances
- Humans
- Female
- Endocrinology & Metabolism
- Cross Reactions
- Chorionic Gonadotropin
- Cell Line
- 3202 Clinical sciences
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Story, M. T., & Hussa, R. O. (1980). Ectopic secretion of complete human chorionic gonadotropin and beta-subunit by human cervical carcinoma cells lines. J Clin Endocrinol Metab, 50(6), 1057–1061. https://doi.org/10.1210/jcem-50-6-1057
Story, M. T., and R. O. Hussa. “Ectopic secretion of complete human chorionic gonadotropin and beta-subunit by human cervical carcinoma cells lines.” J Clin Endocrinol Metab 50, no. 6 (June 1980): 1057–61. https://doi.org/10.1210/jcem-50-6-1057.
Story MT, Hussa RO. Ectopic secretion of complete human chorionic gonadotropin and beta-subunit by human cervical carcinoma cells lines. J Clin Endocrinol Metab. 1980 Jun;50(6):1057–61.
Story, M. T., and R. O. Hussa. “Ectopic secretion of complete human chorionic gonadotropin and beta-subunit by human cervical carcinoma cells lines.” J Clin Endocrinol Metab, vol. 50, no. 6, June 1980, pp. 1057–61. Pubmed, doi:10.1210/jcem-50-6-1057.
Story MT, Hussa RO. Ectopic secretion of complete human chorionic gonadotropin and beta-subunit by human cervical carcinoma cells lines. J Clin Endocrinol Metab. 1980 Jun;50(6):1057–1061.
Published In
J Clin Endocrinol Metab
DOI
ISSN
0021-972X
Publication Date
June 1980
Volume
50
Issue
6
Start / End Page
1057 / 1061
Location
United States
Related Subject Headings
- Uterine Cervical Neoplasms
- Radioimmunoassay
- Macromolecular Substances
- Humans
- Female
- Endocrinology & Metabolism
- Cross Reactions
- Chorionic Gonadotropin
- Cell Line
- 3202 Clinical sciences