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Utilization of Cardiopulmonary Bypass in Trauma Patients: A Multi-Institutional Study of the American Association for the Surgery of Trauma.

Journal articles  - Journal Article, Multicenter Study
Karamchandani, MM; Nahmias, J; Alvarez, C; Callcut, RA; Stadeli, KM; Park, C; Kost, M; Bruce, N; Biffl, WL; Al-Dulaimi, H; Wood, FC; Ghio, M ...
Published in: Am Surg
July 2026

BackgroundThe purpose of this descriptive study was to characterize the utilization and outcomes of CPB after trauma.MethodsThis is an AAST-sponsored retrospective (2011-2021) multicenter (32 centers) study of all adult trauma patients undergoing CPB. Univariate analysis comparing demographics, clinical characteristics and the study outcomes were performed between those who required CPB≤2 hours, >2-24 hours, and >24 hours from the arrival. The primary outcome was mortality.ResultsThere were 113 patients, 63% sustained blunt trauma. The most common injuries were cardiac (42%), thoracic aorta (42%), and pericardial tamponade (25%). The three most common reasons to use CPB were aortic repair (32%), cardiopulmonary resuscitation (20%), and cardiac repair (15%). CPB was performed within 2 hours in 44(39%), and 21(19%) underwent CPB after 24-hours. Penetrating mechanisms of injury 24 (55%) (P = .009), higher rate of hypotension (SBP <80 mmHg) 15 (71%) (P = .002) were more common in CPB≤2-hours. Septal (P = .001) and valvular (P = .002) injuries were more frequent in CPB >24 hours, otherwise there were no differences in injury patterns among CPB ≤2 hours, >2-24 hours, and >24 hours. Cardiac repair was the most common indications for CPB ≤2 hours (P = .002), aorta repair was more common in CPB 2-24 hours (P = .03). Complications were not different between CPB ≤2 hours, >2-24 hours, and >24 hours. Among survivors, no differences in terms of discharge disposition, hospital LOS were found (all P > .05). Mortality was 22% with 96% of them undergoing CPB in the first 24 hours (P < .001).ConclusionsCPB is rarely used for traumatic injuries. The true impact of CPB is unknown and should be studied in comparison to patients with cardiovascular injuries that are repaired without CPB.Level of EvidenceLevel IV; Therapeutic/Care Management.

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Published In

Am Surg

DOI

EISSN

1555-9823

Publication Date

July 2026

Volume

92

Issue

7

Start / End Page

1891 / 1901

Location

United States

Related Subject Headings

  • Wounds, Nonpenetrating
  • Wounds and Injuries
  • United States
  • Time Factors
  • Surgery
  • Retrospective Studies
  • Middle Aged
  • Male
  • Humans
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
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Karamchandani, M. M., Nahmias, J., Alvarez, C., Callcut, R. A., Stadeli, K. M., Park, C., … Bugaev, N. (2026). Utilization of Cardiopulmonary Bypass in Trauma Patients: A Multi-Institutional Study of the American Association for the Surgery of Trauma. Am Surg, 92(7), 1891–1901. https://doi.org/10.1177/00031348261425181
Karamchandani, Manish M., Jeffry Nahmias, Claudia Alvarez, Rachael A. Callcut, Kathryn M. Stadeli, Caroline Park, Melissa Kost, et al. “Utilization of Cardiopulmonary Bypass in Trauma Patients: A Multi-Institutional Study of the American Association for the Surgery of Trauma.Am Surg 92, no. 7 (July 2026): 1891–1901. https://doi.org/10.1177/00031348261425181.
Karamchandani MM, Nahmias J, Alvarez C, Callcut RA, Stadeli KM, Park C, et al. Utilization of Cardiopulmonary Bypass in Trauma Patients: A Multi-Institutional Study of the American Association for the Surgery of Trauma. Am Surg. 2026 Jul;92(7):1891–901.
Karamchandani, Manish M., et al. “Utilization of Cardiopulmonary Bypass in Trauma Patients: A Multi-Institutional Study of the American Association for the Surgery of Trauma.Am Surg, vol. 92, no. 7, July 2026, pp. 1891–901. Pubmed, doi:10.1177/00031348261425181.
Karamchandani MM, Nahmias J, Alvarez C, Callcut RA, Stadeli KM, Park C, Kost M, Bruce N, Biffl WL, Al-Dulaimi H, Wood FC, Gushing JD, Taghavi S, Ghio M, Kirsch JM, Staszak JK, Collier B, Jordan MB, Sciarretta JD, Chow K, Evans DC, Rady EW, Mukherjee K, Winchell RJ, Hsu CY, Brasel K, Henry R, Doles B, Smith B, Williams JB, Udekwu PO, Bhattacharya B, Jones T, Byrne J, Haut E, Jacobson LE, Williams JM, Brat G, Beaulieu-Jones BR, Harfouche MN, Rao AS, Bauman ZM, Goodman M, Craugh L, Winfield RD, Rakhit S, Maiga AW, Blay E, Fernández LG, Pero B, Brown CVR, Weresh H, Wilson CT, Miles TJ, Barmparas G, Margulies DR, Ra J, O’Keeffe T, Fickle J, Draper B, Barbosa R, Bugaev N. Utilization of Cardiopulmonary Bypass in Trauma Patients: A Multi-Institutional Study of the American Association for the Surgery of Trauma. Am Surg. 2026 Jul;92(7):1891–1901.

Published In

Am Surg

DOI

EISSN

1555-9823

Publication Date

July 2026

Volume

92

Issue

7

Start / End Page

1891 / 1901

Location

United States

Related Subject Headings

  • Wounds, Nonpenetrating
  • Wounds and Injuries
  • United States
  • Time Factors
  • Surgery
  • Retrospective Studies
  • Middle Aged
  • Male
  • Humans
  • Female