Phase 1 trial of pre-operative image guided intensity modulated photon radiotherapy with simultaneously integrated boost to the high-risk margin for patients with retroperitoneal sarcoma.
Journal articles
- Journal Article
Liu, KX; Chen, Y-L; Yeap, BY; Hitchcock, YJ; Salerno, KE; Kane, JM; Haynes, AB; Kirsch, DG; Blazer, DG; Michalski, JM; Baldini, EH; Wang, D ...
Published in: Radiother Oncol
August 2026
This phase 1 trial using intensity modulated photon pre-operative radiotherapy for patients with retroperitoneal sarcoma demonstrated that the dose can be safely escalated to 63.0 Gy to a select tumor volume deemed at high risk for positive margins. Thus, this approach is worthy of further prospective study with larger cohorts.
Duke Scholars
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Published In
Radiother Oncol
DOI
EISSN
1879-0887
Publication Date
August 2026
Volume
221
Start / End Page
111621
Location
Ireland
Related Subject Headings
- Sarcoma
- Retroperitoneal Neoplasms
- Radiotherapy, Intensity-Modulated
- Radiotherapy, Image-Guided
- Radiotherapy Dosage
- Photons
- Oncology & Carcinogenesis
- Male
- Humans
- Female
Citation
APA
Chicago
ICMJE
MLA
NLM
Liu, K. X., Chen, Y.-L., Yeap, B. Y., Hitchcock, Y. J., Salerno, K. E., Kane, J. M., … DeLaney, T. F. (2026). Phase 1 trial of pre-operative image guided intensity modulated photon radiotherapy with simultaneously integrated boost to the high-risk margin for patients with retroperitoneal sarcoma. Radiother Oncol, 221, 111621. https://doi.org/10.1016/j.radonc.2026.111621
Liu, Kevin X., Yen-Lin Chen, Beow Y. Yeap, Ying J. Hitchcock, Kilian E. Salerno, John M. Kane, Alex B. Haynes, et al. “Phase 1 trial of pre-operative image guided intensity modulated photon radiotherapy with simultaneously integrated boost to the high-risk margin for patients with retroperitoneal sarcoma.” Radiother Oncol 221 (August 2026): 111621. https://doi.org/10.1016/j.radonc.2026.111621.
Liu KX, Chen Y-L, Yeap BY, Hitchcock YJ, Salerno KE, Kane JM, et al. Phase 1 trial of pre-operative image guided intensity modulated photon radiotherapy with simultaneously integrated boost to the high-risk margin for patients with retroperitoneal sarcoma. Radiother Oncol. 2026 Aug;221:111621.
Liu, Kevin X., et al. “Phase 1 trial of pre-operative image guided intensity modulated photon radiotherapy with simultaneously integrated boost to the high-risk margin for patients with retroperitoneal sarcoma.” Radiother Oncol, vol. 221, Aug. 2026, p. 111621. Pubmed, doi:10.1016/j.radonc.2026.111621.
Liu KX, Chen Y-L, Yeap BY, Hitchcock YJ, Salerno KE, Kane JM, Haynes AB, Kirsch DG, Blazer DG, Michalski JM, Baldini EH, Wang D, Choy E, Nielsen GP, Mullen JT, DeLaney TF. Phase 1 trial of pre-operative image guided intensity modulated photon radiotherapy with simultaneously integrated boost to the high-risk margin for patients with retroperitoneal sarcoma. Radiother Oncol. 2026 Aug;221:111621.
Published In
Radiother Oncol
DOI
EISSN
1879-0887
Publication Date
August 2026
Volume
221
Start / End Page
111621
Location
Ireland
Related Subject Headings
- Sarcoma
- Retroperitoneal Neoplasms
- Radiotherapy, Intensity-Modulated
- Radiotherapy, Image-Guided
- Radiotherapy Dosage
- Photons
- Oncology & Carcinogenesis
- Male
- Humans
- Female