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CSF-venous Fistulas Arising in the Absence of Nerve Root Sleeve Diverticula: A Multi-Center Review.

Journal articles  - Journal Article
Madhavan, AA; Kodet, ML; Weant, EH; Kranz, PG; Schievink, WI; Amrhein, TJ; Gray, L; Malinzak, MD; Carlton Jones, L; Lennarson, P; Callen, AL
Published in: AJNR Am J Neuroradiol
June 24, 2026

CSF-venous fistulas are an increasingly recognized cause of spontaneous intracranial hypotension. Most CSF-venous fistulas arise from meningeal diverticula along the nerve root sleeves. Therefore, the presence of diverticula on spine MRI may serve as an important predictor for the presence of a CSF-venous fistula on decubitus myelography. Rare cases of CSF-venous fistulas that occur without an associated meningeal diverticulum have been identified. These occur in two varieties: 1) fistulas that arise from a nerve root sleeve that does not harbor a diverticulum and 2) fistulas that arise directly from the common thecal sac, separate from the nerve root sleeve complex. In this multi-institutional, retrospective case series, we identified patients with these two variants of CSF-venous fistulas. We sought to describe the clinical and imaging characteristics of these patients and elucidate how they may differ from those with typical CSF-venous fistulas arising from meningeal diverticula.

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Published In

AJNR Am J Neuroradiol

DOI

EISSN

1936-959X

Publication Date

June 24, 2026

Location

United States

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • 3406 Physical chemistry
  • 3209 Neurosciences
  • 3202 Clinical sciences
 

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Madhavan, A. A., Kodet, M. L., Weant, E. H., Kranz, P. G., Schievink, W. I., Amrhein, T. J., … Callen, A. L. (2026). CSF-venous Fistulas Arising in the Absence of Nerve Root Sleeve Diverticula: A Multi-Center Review. AJNR Am J Neuroradiol. https://doi.org/10.3174/ajnr.A9493
Madhavan, Ajay A., Michelle L. Kodet, Erin Hope Weant, Peter G. Kranz, Wouter I. Schievink, Timothy J. Amrhein, Linda Gray, et al. “CSF-venous Fistulas Arising in the Absence of Nerve Root Sleeve Diverticula: A Multi-Center Review.AJNR Am J Neuroradiol, June 24, 2026. https://doi.org/10.3174/ajnr.A9493.
Madhavan AA, Kodet ML, Weant EH, Kranz PG, Schievink WI, Amrhein TJ, et al. CSF-venous Fistulas Arising in the Absence of Nerve Root Sleeve Diverticula: A Multi-Center Review. AJNR Am J Neuroradiol. 2026 Jun 24;
Madhavan, Ajay A., et al. “CSF-venous Fistulas Arising in the Absence of Nerve Root Sleeve Diverticula: A Multi-Center Review.AJNR Am J Neuroradiol, June 2026. Pubmed, doi:10.3174/ajnr.A9493.
Madhavan AA, Kodet ML, Weant EH, Kranz PG, Schievink WI, Amrhein TJ, Gray L, Malinzak MD, Carlton Jones L, Lennarson P, Callen AL. CSF-venous Fistulas Arising in the Absence of Nerve Root Sleeve Diverticula: A Multi-Center Review. AJNR Am J Neuroradiol. 2026 Jun 24;

Published In

AJNR Am J Neuroradiol

DOI

EISSN

1936-959X

Publication Date

June 24, 2026

Location

United States

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • 3406 Physical chemistry
  • 3209 Neurosciences
  • 3202 Clinical sciences