Scholars@Duke publication: Supplementary Figure S6 from Single-Cell Transcriptomics Reveals Immune Landscape Dynamics in Metastatic Hormone Receptor–Positive Breast Cancer Treated with Abemaciclib and Endocrine Therapy

Supplementary Figure S6 from Single-Cell Transcriptomics Reveals Immune Landscape Dynamics in Metastatic Hormone Receptor–Positive Breast Cancer Treated with Abemaciclib and Endocrine Therapy

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Strawser, CH; Chakraborty, B; Michaud, D; Chang, C-Y; Dent, S; Jain, V; Tolaney, SM; Weinhold, K; McAllister, SS; Miller, KE; Steadman, K ...

August 3, 2026

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<p>Supplementary Fig. S6. A) UMAP visualization of myeloid cell type markers for macrophages (CD68), M2-like macrophages (CD163), antigen-presenting cells (HLA-DRA), monocytes (CD14), dendritic cells (CD1C), and mast cells (KIT). B) Relative proportions of myeloid clusters per patient per timepoint per metastasis site. C) Relative proportions of myeloid clusters per patient per timepoint per response group.</p>

Duke Scholars

Author Donald Patrick McDonnell Pharmacology & Cancer Biology

Author Kent James Weinhold Surgery, Surgical Sciences

Author Binita Chakraborty

Author Ching-yi Chang Pharmacology & Cancer Biology

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DOI

10.1158/1078-0432.33142983

Publication Date

August 3, 2026

Citation

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Strawser, C. H., Chakraborty, B., Michaud, D., Chang, C.-Y., Dent, S., Jain, V., … Sammons, S. (2026). Supplementary Figure S6 from Single-Cell Transcriptomics Reveals Immune Landscape Dynamics in Metastatic Hormone Receptor–Positive Breast Cancer Treated with Abemaciclib and Endocrine Therapy. https://doi.org/10.1158/1078-0432.33142983

Strawser, Corinne H., Binita Chakraborty, Daniel Michaud, Ching-Yi Chang, Susan Dent, Vaibhav Jain, Sara M. Tolaney, et al. “Supplementary Figure S6 from Single-Cell Transcriptomics Reveals Immune Landscape Dynamics in Metastatic Hormone Receptor–Positive Breast Cancer Treated with Abemaciclib and Endocrine Therapy,” August 3, 2026. https://doi.org/10.1158/1078-0432.33142983.

Strawser CH, Chakraborty B, Michaud D, Chang C-Y, Dent S, Jain V, et al. Supplementary Figure S6 from Single-Cell Transcriptomics Reveals Immune Landscape Dynamics in Metastatic Hormone Receptor–Positive Breast Cancer Treated with Abemaciclib and Endocrine Therapy. 2026.

Strawser, Corinne H., et al. Supplementary Figure S6 from Single-Cell Transcriptomics Reveals Immune Landscape Dynamics in Metastatic Hormone Receptor–Positive Breast Cancer Treated with Abemaciclib and Endocrine Therapy. 3 Aug. 2026. Crossref, doi:10.1158/1078-0432.33142983.

Strawser CH, Chakraborty B, Michaud D, Chang C-Y, Dent S, Jain V, Tolaney SM, Weinhold K, McAllister SS, Miller KE, Steadman K, Arvai S, Hocke E, Agrawal Y, Perou CM, Goel S, McDonnell DP, Guerriero JL, Sammons S. Supplementary Figure S6 from Single-Cell Transcriptomics Reveals Immune Landscape Dynamics in Metastatic Hormone Receptor–Positive Breast Cancer Treated with Abemaciclib and Endocrine Therapy. 2026.

DOI

10.1158/1078-0432.33142983

Publication Date

August 3, 2026