Scholars@Duke publication: Reduction of granulosa cell progesterone secretion in vitro by intraovarian implants of antiandrogen.

Reduction of granulosa cell progesterone secretion in vitro by intraovarian implants of antiandrogen.

Publication , Journal Article

Schomberg, DW; Williams, RF; Tyrey, L; Ulberg, LC

Published in: Endocrinology

March 1978

Intra-ovarian Silastic implants containing the antiandrogen, Flutamide, or its active metabolite, reduced the level of progesterone secretion in porcine granulosa cell cultures by approximately 50%. These results complement recent observations in vitro suggesting a role for androgen in granulosa cell steroidogenesis during follicular development.

Duke Scholars

Author David William Schomberg Obstetrics and Gynecology, Reproductive Sciences

Published In

Endocrinology

DOI

10.1210/endo-102-3-984

ISSN

0013-7227

Publication Date

March 1978

Volume

102

Issue

Start / End Page

984 / 987

Location

United States

Related Subject Headings

Swine
Progesterone
Ovary
Granulosa Cells
Flutamide
Female
Endocrinology & Metabolism
Drug Implants
Animals
Anilides

Citation

APA

Chicago

ICMJE

MLA

NLM

Schomberg, D. W., Williams, R. F., Tyrey, L., & Ulberg, L. C. (1978). Reduction of granulosa cell progesterone secretion in vitro by intraovarian implants of antiandrogen. Endocrinology, 102(3), 984–987. https://doi.org/10.1210/endo-102-3-984

Schomberg, D. W., R. F. Williams, L. Tyrey, and L. C. Ulberg. “Reduction of granulosa cell progesterone secretion in vitro by intraovarian implants of antiandrogen.” Endocrinology 102, no. 3 (March 1978): 984–87. https://doi.org/10.1210/endo-102-3-984.

Schomberg DW, Williams RF, Tyrey L, Ulberg LC. Reduction of granulosa cell progesterone secretion in vitro by intraovarian implants of antiandrogen. Endocrinology. 1978 Mar;102(3):984–7.

Schomberg, D. W., et al. “Reduction of granulosa cell progesterone secretion in vitro by intraovarian implants of antiandrogen.” Endocrinology, vol. 102, no. 3, Mar. 1978, pp. 984–87. Pubmed, doi:10.1210/endo-102-3-984.

Schomberg DW, Williams RF, Tyrey L, Ulberg LC. Reduction of granulosa cell progesterone secretion in vitro by intraovarian implants of antiandrogen. Endocrinology. 1978 Mar;102(3):984–987.