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Transconjunctival sinusotomy using the 193-nm excimer laser.

Publication ,  Journal Article
Campos, M; Lee, PP; Trokel, SL; Taylor, HR; McDonnell, PJ
Published in: Acta Ophthalmol (Copenh)
December 1994

Successful surgical management of glaucoma is limited as a consequence of undesired fibroblastic response of episcleral tissues. In 10 rabbit and three human eye bank eyes, we have performed a modified sinusotomy procedure using the 193-nm excimer laser. The technique is minimally invasive. Conjunctiva is pulled over the corneoscleral limbus, and a slit-shaped (1 x 2 mm) excimer beam ablates through conjunctiva and external sclera until penetrating the outer wall of Schlemm's canal, at which time brisk egress of fluid is noted. The conjunctiva is allowed to retract, and a conjunctival bleb is formed. A single suture is used to close the conjunctival defect. Intraocular pressure in the rabbit eye was decreased from 10.0 +/- 1.8 to 4.9 +/- 1.8 mmHg immediately after surgery (p < 0.0001). Histology revealed a partial thickness, smooth-walled ablation consistent with a sinusotomy. This procedure is minimally invasive and may be useful for management of glaucoma, particularly when a substantial component of the impediment to aqueous outflow is external to the trabecular meshwork.

Duke Scholars

Published In

Acta Ophthalmol (Copenh)

DOI

ISSN

0001-639X

Publication Date

December 1994

Volume

72

Issue

6

Start / End Page

707 / 711

Location

Denmark

Related Subject Headings

  • Rabbits
  • Laser Therapy
  • Intraocular Pressure
  • Humans
  • Glaucoma
  • Filtering Surgery
  • Conjunctiva
  • Animals
 

Citation

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Campos, M., Lee, P. P., Trokel, S. L., Taylor, H. R., & McDonnell, P. J. (1994). Transconjunctival sinusotomy using the 193-nm excimer laser. Acta Ophthalmol (Copenh), 72(6), 707–711. https://doi.org/10.1111/j.1755-3768.1994.tb04685.x
Campos, M., P. P. Lee, S. L. Trokel, H. R. Taylor, and P. J. McDonnell. “Transconjunctival sinusotomy using the 193-nm excimer laser.Acta Ophthalmol (Copenh) 72, no. 6 (December 1994): 707–11. https://doi.org/10.1111/j.1755-3768.1994.tb04685.x.
Campos M, Lee PP, Trokel SL, Taylor HR, McDonnell PJ. Transconjunctival sinusotomy using the 193-nm excimer laser. Acta Ophthalmol (Copenh). 1994 Dec;72(6):707–11.
Campos, M., et al. “Transconjunctival sinusotomy using the 193-nm excimer laser.Acta Ophthalmol (Copenh), vol. 72, no. 6, Dec. 1994, pp. 707–11. Pubmed, doi:10.1111/j.1755-3768.1994.tb04685.x.
Campos M, Lee PP, Trokel SL, Taylor HR, McDonnell PJ. Transconjunctival sinusotomy using the 193-nm excimer laser. Acta Ophthalmol (Copenh). 1994 Dec;72(6):707–711.

Published In

Acta Ophthalmol (Copenh)

DOI

ISSN

0001-639X

Publication Date

December 1994

Volume

72

Issue

6

Start / End Page

707 / 711

Location

Denmark

Related Subject Headings

  • Rabbits
  • Laser Therapy
  • Intraocular Pressure
  • Humans
  • Glaucoma
  • Filtering Surgery
  • Conjunctiva
  • Animals