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Evaluation of tilted cone-beam CT orbits in the development of a dedicated hybrid mammotomograph.

Publication ,  Journal Article
Madhav, P; Crotty, DJ; McKinley, RL; Tornai, MP
Published in: Phys Med Biol
June 21, 2009

A compact dedicated 3D breast SPECT-CT (mammotomography) system is currently under development. In its initial prototype, the cone-beam CT sub-system is restricted to a fixed-tilt circular rotation around the patient's pendant breast. This study evaluated stationary-tilt angles for the CT sub-system that will enable maximal volumetric sampling and viewing of the breast and chest wall. Images of geometric/anthropomorphic phantoms were acquired using various fixed-tilt circular and 3D sinusoidal trajectories. The iteratively reconstructed images showed more distortion and attenuation coefficient inaccuracy from tilted cone-beam orbits than from the complex trajectory. Additionally, line profiles illustrated cupping artifacts in planes distal to the central plane of the tilted cone-beam, otherwise not apparent for images acquired with complex trajectories. This indicates that undersampled cone-beam data may be an additional cause of cupping artifacts. High-frequency objects could be distinguished for all trajectories, but their shapes and locations were corrupted by out-of-plane frequency information. Although more acrylic balls were visualized with a fixed-tilt and nearly flat cone-beam at the posterior of the breast, 3D complex trajectories have less distortion and more complete sampling throughout the reconstruction volume. While complex trajectories would ideally be preferred, negatively fixed-tilt source-detector configuration demonstrates minimally distorted patient images.

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Published In

Phys Med Biol

DOI

ISSN

0031-9155

Publication Date

June 21, 2009

Volume

54

Issue

12

Start / End Page

3659 / 3676

Location

England

Related Subject Headings

  • Tomography, Emission-Computed, Single-Photon
  • Systems Integration
  • Subtraction Technique
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Phantoms, Imaging
  • Nuclear Medicine & Medical Imaging
  • Mammography
  • Equipment Failure Analysis
  • Equipment Design
 

Citation

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Madhav, P., Crotty, D. J., McKinley, R. L., & Tornai, M. P. (2009). Evaluation of tilted cone-beam CT orbits in the development of a dedicated hybrid mammotomograph. Phys Med Biol, 54(12), 3659–3676. https://doi.org/10.1088/0031-9155/54/12/004
Madhav, P., D. J. Crotty, R. L. McKinley, and M. P. Tornai. “Evaluation of tilted cone-beam CT orbits in the development of a dedicated hybrid mammotomograph.Phys Med Biol 54, no. 12 (June 21, 2009): 3659–76. https://doi.org/10.1088/0031-9155/54/12/004.
Madhav P, Crotty DJ, McKinley RL, Tornai MP. Evaluation of tilted cone-beam CT orbits in the development of a dedicated hybrid mammotomograph. Phys Med Biol. 2009 Jun 21;54(12):3659–76.
Madhav, P., et al. “Evaluation of tilted cone-beam CT orbits in the development of a dedicated hybrid mammotomograph.Phys Med Biol, vol. 54, no. 12, June 2009, pp. 3659–76. Pubmed, doi:10.1088/0031-9155/54/12/004.
Madhav P, Crotty DJ, McKinley RL, Tornai MP. Evaluation of tilted cone-beam CT orbits in the development of a dedicated hybrid mammotomograph. Phys Med Biol. 2009 Jun 21;54(12):3659–3676.
Journal cover image

Published In

Phys Med Biol

DOI

ISSN

0031-9155

Publication Date

June 21, 2009

Volume

54

Issue

12

Start / End Page

3659 / 3676

Location

England

Related Subject Headings

  • Tomography, Emission-Computed, Single-Photon
  • Systems Integration
  • Subtraction Technique
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Phantoms, Imaging
  • Nuclear Medicine & Medical Imaging
  • Mammography
  • Equipment Failure Analysis
  • Equipment Design