Separation of promethazine and thioridazine using capillary electrophoresis with end-column amperometric detection.
Publication
, Journal Article
Wang, R; Lu, X; Wu, M; Wang, E
Published in: J Chromatogr B Biomed Sci Appl
January 22, 1999
Promethazine and thioridazine were separated and detected by capillary electrophoresis with end-column amperometric detection. The influence of pH value on oxidation potential, the peak current and the resolution were studied and the following conditions was selected: 0.03 M Na2HPO4 and 0.015 M citric acid at pH 3.0, detection potential at 1.10 V. The detection limits of these two substances were in the range of 10(-8) mol/l. The linear range spanned two to three orders of magnitude. This method was applied to the detection of promethazine and thioridazine spiked in urine.
Published In
J Chromatogr B Biomed Sci Appl
DOI
ISSN
1387-2273
Publication Date
January 22, 1999
Volume
721
Issue
2
Start / End Page
327 / 332
Location
Netherlands
Related Subject Headings
- Thioridazine
- Reproducibility of Results
- Promethazine
- Oxidation-Reduction
- Hydrogen-Ion Concentration
- Humans
- Histamine H1 Antagonists
- Electrophoresis, Capillary
- Electrodes
- Electrochemistry
Citation
APA
Chicago
ICMJE
MLA
NLM
Wang, R., Lu, X., Wu, M., & Wang, E. (1999). Separation of promethazine and thioridazine using capillary electrophoresis with end-column amperometric detection. J Chromatogr B Biomed Sci Appl, 721(2), 327–332. https://doi.org/10.1016/s0378-4347(98)00485-x
Wang, R., X. Lu, M. Wu, and E. Wang. “Separation of promethazine and thioridazine using capillary electrophoresis with end-column amperometric detection.” J Chromatogr B Biomed Sci Appl 721, no. 2 (January 22, 1999): 327–32. https://doi.org/10.1016/s0378-4347(98)00485-x.
Wang R, Lu X, Wu M, Wang E. Separation of promethazine and thioridazine using capillary electrophoresis with end-column amperometric detection. J Chromatogr B Biomed Sci Appl. 1999 Jan 22;721(2):327–32.
Wang, R., et al. “Separation of promethazine and thioridazine using capillary electrophoresis with end-column amperometric detection.” J Chromatogr B Biomed Sci Appl, vol. 721, no. 2, Jan. 1999, pp. 327–32. Pubmed, doi:10.1016/s0378-4347(98)00485-x.
Wang R, Lu X, Wu M, Wang E. Separation of promethazine and thioridazine using capillary electrophoresis with end-column amperometric detection. J Chromatogr B Biomed Sci Appl. 1999 Jan 22;721(2):327–332.
Published In
J Chromatogr B Biomed Sci Appl
DOI
ISSN
1387-2273
Publication Date
January 22, 1999
Volume
721
Issue
2
Start / End Page
327 / 332
Location
Netherlands
Related Subject Headings
- Thioridazine
- Reproducibility of Results
- Promethazine
- Oxidation-Reduction
- Hydrogen-Ion Concentration
- Humans
- Histamine H1 Antagonists
- Electrophoresis, Capillary
- Electrodes
- Electrochemistry