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Unprocessed real-time imaging of vitreoretinal surgical maneuvers using a microscope-integrated spectral-domain optical coherence tomography system.

Publication ,  Journal Article
Hahn, P; Migacz, J; O'Connell, R; Izatt, JA; Toth, CA
Published in: Graefes Arch Clin Exp Ophthalmol
January 2013

BACKGROUND: We have recently developed a microscope-integrated spectral-domain optical coherence tomography (MIOCT) device towards intrasurgical cross-sectional imaging of surgical maneuvers. In this report, we explore the capability of MIOCT to acquire real-time video imaging of vitreoretinal surgical maneuvers without post-processing modifications. METHODS: Standard 3-port vitrectomy was performed in human during scheduled surgery as well as in cadaveric porcine eyes. MIOCT imaging of human subjects was performed in healthy normal volunteers and intraoperatively at a normal pause immediately following surgical manipulations, under an Institutional Review Board-approved protocol, with informed consent from all subjects. Video MIOCT imaging of live surgical manipulations was performed in cadaveric porcine eyes by carefully aligning B-scans with instrument orientation and movement. Inverted imaging was performed by lengthening of the reference arm to a position beyond the choroid. RESULTS: Unprocessed MIOCT imaging was successfully obtained in healthy human volunteers and in human patients undergoing surgery, with visualization of post-surgical changes in unprocessed single B-scans. Real-time, unprocessed MIOCT video imaging was successfully obtained in cadaveric porcine eyes during brushing of the retina with the Tano scraper, peeling of superficial retinal tissue with intraocular forceps, and separation of the posterior hyaloid face. Real-time inverted imaging enabled imaging without complex conjugate artifacts. CONCLUSIONS: MIOCT is capable of unprocessed imaging of the macula in human patients undergoing surgery and of unprocessed, real-time, video imaging of surgical maneuvers in model eyes. These capabilities represent an important step towards development of MIOCT for efficient, real-time imaging of manipulations during human surgery.

Published In

Graefes Arch Clin Exp Ophthalmol

DOI

EISSN

1435-702X

Publication Date

January 2013

Volume

251

Issue

1

Start / End Page

213 / 220

Location

Germany

Related Subject Headings

  • Vitreoretinal Surgery
  • Vitrectomy
  • Video Recording
  • Tomography, Optical Coherence
  • Swine
  • Retina
  • Ophthalmology & Optometry
  • Microscopy
  • Humans
  • Diagnostic Imaging
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Hahn, P., Migacz, J., O’Connell, R., Izatt, J. A., & Toth, C. A. (2013). Unprocessed real-time imaging of vitreoretinal surgical maneuvers using a microscope-integrated spectral-domain optical coherence tomography system. Graefes Arch Clin Exp Ophthalmol, 251(1), 213–220. https://doi.org/10.1007/s00417-012-2052-2
Hahn, Paul, Justin Migacz, Rachelle O’Connell, Joseph A. Izatt, and Cynthia A. Toth. “Unprocessed real-time imaging of vitreoretinal surgical maneuvers using a microscope-integrated spectral-domain optical coherence tomography system.Graefes Arch Clin Exp Ophthalmol 251, no. 1 (January 2013): 213–20. https://doi.org/10.1007/s00417-012-2052-2.
Hahn P, Migacz J, O’Connell R, Izatt JA, Toth CA. Unprocessed real-time imaging of vitreoretinal surgical maneuvers using a microscope-integrated spectral-domain optical coherence tomography system. Graefes Arch Clin Exp Ophthalmol. 2013 Jan;251(1):213–20.
Hahn, Paul, et al. “Unprocessed real-time imaging of vitreoretinal surgical maneuvers using a microscope-integrated spectral-domain optical coherence tomography system.Graefes Arch Clin Exp Ophthalmol, vol. 251, no. 1, Jan. 2013, pp. 213–20. Pubmed, doi:10.1007/s00417-012-2052-2.
Hahn P, Migacz J, O’Connell R, Izatt JA, Toth CA. Unprocessed real-time imaging of vitreoretinal surgical maneuvers using a microscope-integrated spectral-domain optical coherence tomography system. Graefes Arch Clin Exp Ophthalmol. 2013 Jan;251(1):213–220.
Journal cover image

Published In

Graefes Arch Clin Exp Ophthalmol

DOI

EISSN

1435-702X

Publication Date

January 2013

Volume

251

Issue

1

Start / End Page

213 / 220

Location

Germany

Related Subject Headings

  • Vitreoretinal Surgery
  • Vitrectomy
  • Video Recording
  • Tomography, Optical Coherence
  • Swine
  • Retina
  • Ophthalmology & Optometry
  • Microscopy
  • Humans
  • Diagnostic Imaging