The superfamily of heptahelical receptors.
Publication
, Journal Article
Lefkowitz, RJ
Published in: Nat Cell Biol
July 2000
Despite a growing appreciation of functional analogies between visual and hormonal signalling systems in the early 1980s, the discovery of the close structural relationship between rhodopsin and the beta2-adrenergic receptor, and of the existence of a larger 'superfamily' of such receptors, came as a total surprise. Here I provide a personal perspective on events leading up to and flowing from this exciting discovery that opened up a vast field of research.
Duke Scholars
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Published In
Nat Cell Biol
DOI
ISSN
1465-7392
Publication Date
July 2000
Volume
2
Issue
7
Start / End Page
E133 / E136
Location
England
Related Subject Headings
- Vision, Ocular
- Second Messenger Systems
- Rhodopsin
- Receptors, Adrenergic, beta
- Mutation
- Humans
- Hormones
- History, 20th Century
- Heterotrimeric GTP-Binding Proteins
- Developmental Biology
Citation
APA
Chicago
ICMJE
MLA
NLM
Lefkowitz, R. J. (2000). The superfamily of heptahelical receptors. Nat Cell Biol, 2(7), E133–E136. https://doi.org/10.1038/35017152
Lefkowitz, R. J. “The superfamily of heptahelical receptors.” Nat Cell Biol 2, no. 7 (July 2000): E133–36. https://doi.org/10.1038/35017152.
Lefkowitz RJ. The superfamily of heptahelical receptors. Nat Cell Biol. 2000 Jul;2(7):E133–6.
Lefkowitz, R. J. “The superfamily of heptahelical receptors.” Nat Cell Biol, vol. 2, no. 7, July 2000, pp. E133–36. Pubmed, doi:10.1038/35017152.
Lefkowitz RJ. The superfamily of heptahelical receptors. Nat Cell Biol. 2000 Jul;2(7):E133–E136.
Published In
Nat Cell Biol
DOI
ISSN
1465-7392
Publication Date
July 2000
Volume
2
Issue
7
Start / End Page
E133 / E136
Location
England
Related Subject Headings
- Vision, Ocular
- Second Messenger Systems
- Rhodopsin
- Receptors, Adrenergic, beta
- Mutation
- Humans
- Hormones
- History, 20th Century
- Heterotrimeric GTP-Binding Proteins
- Developmental Biology