Determination of bioactive peptides using capillary zone electrophoresis/mass spectrometry.
Publication
, Journal Article
Moseley, MA; Deterding, LJ; Tomer, KB; Jorgenson, JW
Published in: Anal Chem
January 15, 1991
Mixtures of bioactive peptides have been analyzed by capillary zone electrophoresis/mass spectrometry (CZE/MS) using an on-line coaxial continuous-flow fast atom bombardment interface. High separation efficiencies (up to 410,000 theoretical plates) were obtained from low femtomole levels of peptides. The analysis of basic peptides was accomplished by using aminopropyl-silylated CZE columns to minimize zone broadening due to adsorption effects. CZE/MS/MS data were acquired from femtomole levels of peptides in electrophoretic real time.
Altmetric Attention Stats
Dimensions Citation Stats
Published In
Anal Chem
DOI
ISSN
0003-2700
Publication Date
January 15, 1991
Volume
63
Issue
2
Start / End Page
109 / 114
Location
United States
Related Subject Headings
- Spectrometry, Mass, Fast Atom Bombardment
- Oligopeptides
- Neuropeptides
- Molecular Sequence Data
- Electrophoresis
- Chemotactic Factors
- Analytical Chemistry
- Amino Acid Sequence
- Absorption
- 4004 Chemical engineering
Citation
APA
Chicago
ICMJE
MLA
NLM
Moseley, M. A., Deterding, L. J., Tomer, K. B., & Jorgenson, J. W. (1991). Determination of bioactive peptides using capillary zone electrophoresis/mass spectrometry. Anal Chem, 63(2), 109–114. https://doi.org/10.1021/ac00002a005
Moseley, M. A., L. J. Deterding, K. B. Tomer, and J. W. Jorgenson. “Determination of bioactive peptides using capillary zone electrophoresis/mass spectrometry.” Anal Chem 63, no. 2 (January 15, 1991): 109–14. https://doi.org/10.1021/ac00002a005.
Moseley MA, Deterding LJ, Tomer KB, Jorgenson JW. Determination of bioactive peptides using capillary zone electrophoresis/mass spectrometry. Anal Chem. 1991 Jan 15;63(2):109–14.
Moseley, M. A., et al. “Determination of bioactive peptides using capillary zone electrophoresis/mass spectrometry.” Anal Chem, vol. 63, no. 2, Jan. 1991, pp. 109–14. Pubmed, doi:10.1021/ac00002a005.
Moseley MA, Deterding LJ, Tomer KB, Jorgenson JW. Determination of bioactive peptides using capillary zone electrophoresis/mass spectrometry. Anal Chem. 1991 Jan 15;63(2):109–114.
Published In
Anal Chem
DOI
ISSN
0003-2700
Publication Date
January 15, 1991
Volume
63
Issue
2
Start / End Page
109 / 114
Location
United States
Related Subject Headings
- Spectrometry, Mass, Fast Atom Bombardment
- Oligopeptides
- Neuropeptides
- Molecular Sequence Data
- Electrophoresis
- Chemotactic Factors
- Analytical Chemistry
- Amino Acid Sequence
- Absorption
- 4004 Chemical engineering