[Endogenous inhibitors of the specific binding of benzodiazepines in the cerebral cortex].
Publication
, Journal Article
Kladnitskiĭ, AV; Mukhin, AG
Published in: Zh Nevropatol Psikhiatr Im S S Korsakova
1988
The nature of inhibitors of [3H]-diazepam (D) specific binding (SB) was studied in 2 fractions of acidic extract from bovine brain cortex. Preparative high-performance liquid chromatography (HPLC), mass spectrometry, UV and IR techniques identified hypoxanthine and inosine as inhibitors of SB D. These substances may participate in the neuronal activity control which is in part mediated by the benzodiazepine receptors.
Published In
Zh Nevropatol Psikhiatr Im S S Korsakova
ISSN
0044-4588
Publication Date
1988
Volume
88
Issue
12
Start / End Page
98 / 103
Location
Russia (Federation)
Related Subject Headings
- Spectrophotometry, Ultraviolet
- Spectrophotometry, Infrared
- Receptors, GABA-A
- Radioligand Assay
- Mass Spectrometry
- Male
- Inosine
- Hypoxanthines
- Hypoxanthine
- Diazepam
Citation
APA
Chicago
ICMJE
MLA
NLM
Kladnitskiĭ, A. V., & Mukhin, A. G. (1988). [Endogenous inhibitors of the specific binding of benzodiazepines in the cerebral cortex]. Zh Nevropatol Psikhiatr Im S S Korsakova, 88(12), 98–103.
Kladnitskiĭ, A. V., and A. G. Mukhin. “[Endogenous inhibitors of the specific binding of benzodiazepines in the cerebral cortex].” Zh Nevropatol Psikhiatr Im S S Korsakova 88, no. 12 (1988): 98–103.
Kladnitskiĭ AV, Mukhin AG. [Endogenous inhibitors of the specific binding of benzodiazepines in the cerebral cortex]. Zh Nevropatol Psikhiatr Im S S Korsakova. 1988;88(12):98–103.
Kladnitskiĭ, A. V., and A. G. Mukhin. “[Endogenous inhibitors of the specific binding of benzodiazepines in the cerebral cortex].” Zh Nevropatol Psikhiatr Im S S Korsakova, vol. 88, no. 12, 1988, pp. 98–103.
Kladnitskiĭ AV, Mukhin AG. [Endogenous inhibitors of the specific binding of benzodiazepines in the cerebral cortex]. Zh Nevropatol Psikhiatr Im S S Korsakova. 1988;88(12):98–103.
Published In
Zh Nevropatol Psikhiatr Im S S Korsakova
ISSN
0044-4588
Publication Date
1988
Volume
88
Issue
12
Start / End Page
98 / 103
Location
Russia (Federation)
Related Subject Headings
- Spectrophotometry, Ultraviolet
- Spectrophotometry, Infrared
- Receptors, GABA-A
- Radioligand Assay
- Mass Spectrometry
- Male
- Inosine
- Hypoxanthines
- Hypoxanthine
- Diazepam