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The efficacy of endosaccular aneurysm occlusion in alleviating neurological deficits produced by mass effect.

Publication ,  Journal Article
Halbach, VV; Higashida, RT; Dowd, CF; Barnwell, SL; Fraser, KW; Smith, TP; Teitelbaum, GP; Hieshima, GB
Published in: J Neurosurg
April 1994

Endovascular obliteration of intracranial aneurysms with preservation of the parent artery (endosaccular occlusion) has been advocated for patients who fail or are excluded from surgical clipping and cannot undergo Hunterian ligation therapy. To clarify the effect that endosaccular occlusion has on the presenting neurological signs, 26 patients with aneurysms and symptoms related to mass effect who underwent this therapy were followed for a mean of 60 months. Only patients with objective neurological deficits who had not suffered a hemorrhage were included in this series. Response to therapy was classified into one of three groups: "resolved," if the patient had complete resolution of presenting signs; "improved," if significant and sustained improvement was recorded in the neurological examinations, and "unchanged," if no change was observed. Thirteen patients (50%) were classified as resolved, 11 (42.3%) as improved, and two (7.7%) as unchanged. A comparison of patients classified as resolved with those who were improved revealed that the former group had less wall calcification (30% vs. 60%) and a shorter duration of symptoms. Patients with neurological sign resolution (62%) were more likely to have totally occluded aneurysms on late follow-up arteriograms than those who had improvement (28%) or were unchanged (0%). This study suggests that endosaccular embolization therapy can improve or alleviate presenting neurological signs unrelated to hemorrhage or distal embolization in the majority of cases.

Duke Scholars

Published In

J Neurosurg

DOI

ISSN

0022-3085

Publication Date

April 1994

Volume

80

Issue

4

Start / End Page

659 / 666

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Neurology & Neurosurgery
  • Nervous System Diseases
  • Middle Aged
  • Male
  • Intracranial Aneurysm
  • Humans
  • Female
  • Embolization, Therapeutic
  • Cerebral Angiography
 

Citation

APA
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MLA
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Halbach, V. V., Higashida, R. T., Dowd, C. F., Barnwell, S. L., Fraser, K. W., Smith, T. P., … Hieshima, G. B. (1994). The efficacy of endosaccular aneurysm occlusion in alleviating neurological deficits produced by mass effect. J Neurosurg, 80(4), 659–666. https://doi.org/10.3171/jns.1994.80.4.0659
Halbach, V. V., R. T. Higashida, C. F. Dowd, S. L. Barnwell, K. W. Fraser, T. P. Smith, G. P. Teitelbaum, and G. B. Hieshima. “The efficacy of endosaccular aneurysm occlusion in alleviating neurological deficits produced by mass effect.J Neurosurg 80, no. 4 (April 1994): 659–66. https://doi.org/10.3171/jns.1994.80.4.0659.
Halbach VV, Higashida RT, Dowd CF, Barnwell SL, Fraser KW, Smith TP, et al. The efficacy of endosaccular aneurysm occlusion in alleviating neurological deficits produced by mass effect. J Neurosurg. 1994 Apr;80(4):659–66.
Halbach, V. V., et al. “The efficacy of endosaccular aneurysm occlusion in alleviating neurological deficits produced by mass effect.J Neurosurg, vol. 80, no. 4, Apr. 1994, pp. 659–66. Pubmed, doi:10.3171/jns.1994.80.4.0659.
Halbach VV, Higashida RT, Dowd CF, Barnwell SL, Fraser KW, Smith TP, Teitelbaum GP, Hieshima GB. The efficacy of endosaccular aneurysm occlusion in alleviating neurological deficits produced by mass effect. J Neurosurg. 1994 Apr;80(4):659–666.

Published In

J Neurosurg

DOI

ISSN

0022-3085

Publication Date

April 1994

Volume

80

Issue

4

Start / End Page

659 / 666

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Neurology & Neurosurgery
  • Nervous System Diseases
  • Middle Aged
  • Male
  • Intracranial Aneurysm
  • Humans
  • Female
  • Embolization, Therapeutic
  • Cerebral Angiography