Sue Jinks-Robertson | Scholars@Duke

Sue Jinks-Robertson
James B. Duke Distinguished Professor of Molecular Genetics and Microbiology

My research focuses on the regulation of genetic stability and primarily uses budding yeast (Saccharomyces cerevisiae ) as a model genetic system. The two primary research goals in the budding yeast system are (1) defining molecular structures and mechanisms of mitotic recombination intermediates and (2) understanding how and why transcription destabilizes the underlying DNA template. We also have initiated studies of mutagenesis in the pathogenic fungus Cryptococcus neoformans . We have found that a shift to the human body temperature mobilizes transposable elements, and suggest that this promotes rapid adaptation to the harsh host environment.

Current Research Interests

Current Appointments & Affiliations

James B. Duke Distinguished Professor of Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2021
Professor of Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2007
Vice-Chair in the Department of Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2017
Professor of Cell Biology, Cell Biology, Basic Science Departments 2022
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2006

Contact Information

384 CARL Box 3020, 213 Research Drive, Durham, NC 27710
384 CARL, Box 3020, Durham, NC 27710
sue.robertson@duke.edu (919) 681-7273
Lab web site

Background
Education, Training, & Certifications
- Ph.D., University of Wisconsin - Madison 1983
Previous Appointments & Affiliations
- Mary Bernheim Distinguished Professor of Medicine, Molecular Genetics and Microbiology, Basic Science Departments 2020 - 2021
- Visiting Professor in the Department of Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2006 - 2007
Leadership & Clinical Positions at Duke
- Director, Cell and Molecular Biology graduate program
  
  Co-leader of the Cancer Genetics and Genomic Research Program of the Duke Cancer Institute
Recognition
In the News
- JAN 30, 2023 Duke Today
  
  Warmer Climate May Drive Fungi to Be More Dangerous to Our Health
- APR 14, 2020
  
  Duke Awards 29 University Distinguished Professorships
- MAY 1, 2019
  
  Two Duke Faculty Elected to National Academy of Sciences
- OCT 18, 2013
  
  Sue Jinks-Robertson elected treasurer of Genetics Society of America
Awards & Honors
Expertise
Subject Headings
Research
Selected Grants
- Cell and Molecular Biology Training Program awarded by National Institutes of Health 2021 - 2026
- Regulation of mitotic genome stability in yeast. awarded by National Institutes of Health 2016 - 2026
- Genetic and Genomics Training Grant awarded by National Institutes of Health 2020 - 2025
- Investigation of transposon mutagenesis in the human fungal pathogen Cryptococcus as an adaptive strategy to generate genetic change and phenotypic variation to enhance pathogenesis or enable drug resistance during infection. awarded by National Institutes of Health 2022 - 2024
- The role of transcription factor proteins in mutagenesis at their binding sites awarded by National Institutes of Health 2020 - 2024
- Genetics Training Grant awarded by National Institutes of Health 1979 - 2020
- Organization and Function of Cellular Structure awarded by National Institutes of Health 1975 - 2020
- Temperature-dependent transposon mobilization in Cryptococcus neoformans awarded by National Institutes of Health 2017 - 2020
- What Happens at a Double Strand Break: Investigating the Role of DNA End Structure in Homologous Recombination awarded by National Institutes of Health 2019
- Non-Canonical Responses to DNA damage in Drosophila Polyploid Cells awarded by National Institutes of Health 2015 - 2017
- Investigating the origin of spontaneous mitotic homologous recombination in Saccharomyces cerevisiae awarded by American Heart Association 2015 - 2017
- Mitotic recombination mechanisms in yeast awarded by National Institutes of Health 2006 - 2016
- Topoisomerase 1 and mutagenesis in yeast awarded by National Institutes of Health 2012 - 2016
- Transcription-associated mutagenesis in yeast awarded by National Institutes of Health 2010 - 2015
- Tolerance of spontaneous and induced DNA in yeast awarded by National Institutes of Health 2002 - 2011
- Role of cross-link formation in Pol Zeta-dependent mutagenesis in S. cerevisiae awarded by National Institutes of Health 2009 - 2010
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Williams, Jonathan D., Demi Zhu, María García-Rubio, Samantha Shaltz, Andrés Aguilera, and Sue Jinks-Robertson. “Spontaneous deamination of cytosine to uracil is biased to the non-transcribed DNA strand in yeast.” Dna Repair (Amst) 126 (June 2023): 103489. https://doi.org/10.1016/j.dnarep.2023.103489.
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  - Gusa, Asiya, Vikas Yadav, Cullen Roth, Jonathan D. Williams, Eva Mei Shouse, Paul Magwene, Joseph Heitman, and Sue Jinks-Robertson. “Genome-wide analysis of heat stress-stimulated transposon mobility in the human fungal pathogen Cryptococcus deneoformans.” Proc Natl Acad Sci U S A 120, no. 4 (January 24, 2023): e2209831120. https://doi.org/10.1073/pnas.2209831120.
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  - Boot, Arnoud, Mo Liu, Nicole Stantial, Viraj Shah, Willie Yu, Karin C. Nitiss, John L. Nitiss, Sue Jinks-Robertson, and Steven G. Rozen. “Recurrent mutations in topoisomerase IIα cause a previously undescribed mutator phenotype in human cancers.” Proc Natl Acad Sci U S A 119, no. 4 (January 25, 2022). https://doi.org/10.1073/pnas.2114024119.
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  - Jinks-Robertson, Sue, and Thomas D. Petes. “Mitotic recombination in yeast: what we know and what we don't know.” Curr Opin Genet Dev 71 (December 2021): 78–85. https://doi.org/10.1016/j.gde.2021.07.002.
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  - Shaltz, Samantha, and Sue Jinks-Robertson. “Mutagenic repair of a ZFN-induced double-strand break in yeast: Effects of cleavage site sequence and spacer size.” Dna Repair (Amst) 108 (December 2021): 103228. https://doi.org/10.1016/j.dnarep.2021.103228.
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  - Stantial, Nicole, Anna Rogojina, Matthew Gilbertson, Yilun Sun, Hannah Miles, Samantha Shaltz, James Berger, Karin C. Nitiss, Sue Jinks-Robertson, and John L. Nitiss. “Trapped topoisomerase II initiates formation of de novo duplications via the nonhomologous end-joining pathway in yeast.” Proc Natl Acad Sci U S A 117, no. 43 (October 27, 2020): 26876–84. https://doi.org/10.1073/pnas.2008721117.
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  - Gamble, Dionna, Samantha Shaltz, and Sue Jinks-Robertson. “Recombinational Repair of Nuclease-Generated Mitotic Double-Strand Breaks with Different End Structures in Yeast.” G3 (Bethesda) 10, no. 10 (October 5, 2020): 3821–29. https://doi.org/10.1534/g3.120.401603.
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  - Williams, Jonathan D., Dominika Houserova, Bradley R. Johnson, Brad Dyniewski, Alexandra Berroyer, Hannah French, Addison A. Barchie, et al. “Characterization of long G4-rich enhancer-associated genomic regions engaging in a novel loop:loop 'G4 Kissing' interaction.” Nucleic Acids Research 48, no. 11 (June 2020): 5907–25. https://doi.org/10.1093/nar/gkaa357.
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  - Gusa, Asiya, Jonathan D. Williams, Jang-Eun Cho, Anna Floyd Averette, Sheng Sun, Eva Mei Shouse, Joseph Heitman, J Andrew Alspaugh, and Sue Jinks-Robertson. “Transposon mobilization in the human fungal pathogen Cryptococcus is mutagenic during infection and promotes drug resistance in vitro.” Proc Natl Acad Sci U S A 117, no. 18 (May 5, 2020): 9973–80. https://doi.org/10.1073/pnas.2001451117.
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  - Gamble, Dionna, Samantha Shaltz, and Sue Jinks-Robertson. “Recombinational repair of nuclease-generated mitotic double-strand breaks with different end structures in yeast,” 2020. https://doi.org/10.1101/2020.07.29.226639.
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  - Stantial, Nicole, Anna Rogojina, Matthew Gilbertson, Yilun Sun, Hannah Miles, Samantha Shaltz, James Berger, Karin Nitiss, Sue Jinks-Robertson, and John Nitiss. “Trapped Topoisomerase II initiates formation ofde novoduplicationsviathe nonhomologous end-joining pathway in yeast,” 2020. https://doi.org/10.1101/2020.05.03.075358.
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  - Gusa, Asiya, and Sue Jinks-Robertson. “Mitotic Recombination and Adaptive Genomic Changes in Human Pathogenic Fungi.” Genes (Basel) 10, no. 11 (November 7, 2019). https://doi.org/10.3390/genes10110901.
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  - Cho, Jang-Eun, and Sue Jinks-Robertson. “Deletions associated with stabilization of the Top1 cleavage complex in yeast are products of the nonhomologous end-joining pathway.” Proc Natl Acad Sci U S A 116, no. 45 (November 5, 2019): 22683–91. https://doi.org/10.1073/pnas.1914081116.
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  - Jenkins, Shirin S., Steven Gore, Xiaoge Guo, Jie Liu, Christopher Ede, Xavier Veaute, Sue Jinks-Robertson, Stephen C. Kowalczykowski, and Wolf-Dietrich Heyer. “Role of the Srs2-Rad51 Interaction Domain in Crossover Control in Saccharomyces cerevisiae.” Genetics 212, no. 4 (August 2019): 1133–45. https://doi.org/10.1534/genetics.119.302337.
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  - Hum, Yee Fang, and Sue Jinks-Robertson. “Mismatch recognition and subsequent processing have distinct effects on mitotic recombination intermediates and outcomes in yeast.” Nucleic Acids Res 47, no. 9 (May 21, 2019): 4554–68. https://doi.org/10.1093/nar/gkz126.
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  - Klein, Hannah L., Giedrė Bačinskaja, Jun Che, Anais Cheblal, Rajula Elango, Anastasiya Epshtein, Devon M. Fitzgerald, et al. “Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways.” Microb Cell 6, no. 1 (January 7, 2019): 1–64. https://doi.org/10.15698/mic2019.01.664.
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  - Hum, Yee Fang, and Sue Jinks-Robertson. “DNA strand-exchange patterns associated with double-strand break-induced and spontaneous mitotic crossovers in Saccharomyces cerevisiae.” Plos Genet 14, no. 3 (March 2018): e1007302. https://doi.org/10.1371/journal.pgen.1007302.
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  - Sloan, Roketa, Shar-Yin Naomi Huang, Yves Pommier, and Sue Jinks-Robertson. “Effects of camptothecin or TOP1 overexpression on genetic stability in Saccharomyces cerevisiae.” Dna Repair (Amst) 59 (November 2017): 69–75. https://doi.org/10.1016/j.dnarep.2017.09.004.
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  - Cho, Jang-Eun, and Sue Jinks-Robertson. “Ribonucleotides and Transcription-Associated Mutagenesis in Yeast.” J Mol Biol 429, no. 21 (October 27, 2017): 3156–67. https://doi.org/10.1016/j.jmb.2016.08.005.
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  - Hum, Yee Fang, and Sue Jinks-Robertson. “Mitotic Gene Conversion Tracts Associated with Repair of a Defined Double-Strand Break in Saccharomyces cerevisiae.” Genetics 207, no. 1 (September 2017): 115–28. https://doi.org/10.1534/genetics.117.300057.
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  - Guo, Xiaoge, Yee Fang Hum, Kevin Lehner, and Sue Jinks-Robertson. “Regulation of hetDNA Length during Mitotic Double-Strand Break Repair in Yeast.” Mol Cell 67, no. 4 (August 17, 2017): 539-549.e4. https://doi.org/10.1016/j.molcel.2017.07.009.
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  - Kim, Nayun, and Sue Jinks-Robertson. “The Top1 paradox: Friend and foe of the eukaryotic genome.” Dna Repair (Amst) 56 (August 2017): 33–41. https://doi.org/10.1016/j.dnarep.2017.06.005.
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  - Hum, Yee Fang, and Sue Jinks-Robertson. “Mitotic gene conversion tracts associated with repair of a defined double-strand break inSaccharomyces cerevisiae,” 2017. https://doi.org/10.1101/132167.
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  - Cho, Jang-Eun, Shar-Yin N. Huang, Peter M. Burgers, Stewart Shuman, Yves Pommier, and Sue Jinks-Robertson. “Parallel analysis of ribonucleotide-dependent deletions produced by yeast Top1 in vitro and in vivo.” Nucleic Acids Res 44, no. 16 (September 19, 2016): 7714–21. https://doi.org/10.1093/nar/gkw495.
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  - O’Connell, Karen, Sue Jinks-Robertson, and Thomas D. Petes. “Elevated Genome-Wide Instability in Yeast Mutants Lacking RNase H Activity.” Genetics 201, no. 3 (November 2015): 963–75. https://doi.org/10.1534/genetics.115.182725.
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  - Cho, Jang-Eun, Nayun Kim, and Sue Jinks-Robertson. “Topoisomerase 1-dependent deletions initiated by incision at ribonucleotides are biased to the non-transcribed strand of a highly activated reporter.” Nucleic Acids Res 43, no. 19 (October 30, 2015): 9306–13. https://doi.org/10.1093/nar/gkv824.
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  - Guo, Xiaoge, Kevin Lehner, Karen O’Connell, Jenny Zhang, Sandeep S. Dave, and Sue Jinks-Robertson. “SMRT Sequencing for Parallel Analysis of Multiple Targets and Accurate SNP Phasing.” G3 (Bethesda) 5, no. 12 (October 23, 2015): 2801–8. https://doi.org/10.1534/g3.115.023317.
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  - Andersen, Sabrina L., Roketa S. Sloan, Thomas D. Petes, and Sue Jinks-Robertson. “Genome-destabilizing effects associated with top1 loss or accumulation of top1 cleavage complexes in yeast.” Plos Genet 11, no. 4 (April 2015): e1005098. https://doi.org/10.1371/journal.pgen.1005098.
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  - Jinks-Robertson, Sue, and Hannah L. Klein. “Ribonucleotides in DNA: hidden in plain sight.” Nat Struct Mol Biol 22, no. 3 (March 2015): 176–78. https://doi.org/10.1038/nsmb.2981.
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  - Yadav, Puja, Victoria Harcy, Juan Lucas Argueso, Margaret Dominska, Sue Jinks-Robertson, and Nayun Kim. “Topoisomerase I plays a critical role in suppressing genome instability at a highly transcribed G-quadruplex-forming sequence.” Plos Genet 10, no. 12 (December 2014): e1004839. https://doi.org/10.1371/journal.pgen.1004839.
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  - Lehner, Kevin, and Sue Jinks-Robertson. “Shared genetic pathways contribute to the tolerance of endogenous and low-dose exogenous DNA damage in yeast.” Genetics 198, no. 2 (October 2014): 519–30. https://doi.org/10.1534/genetics.114.168617.
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  - Brandão, Luis N., Rebecca Ferguson, Irma Santoro, Sue Jinks-Robertson, and Robert A. Sclafani. “The role of Dbf4-dependent protein kinase in DNA polymerase ζ-dependent mutagenesis in Saccharomyces cerevisiae.” Genetics 197, no. 4 (August 2014): 1111–22. https://doi.org/10.1534/genetics.114.165308.
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  - Jinks-Robertson, Sue, and Ashok S. Bhagwat. “Transcription-associated mutagenesis.” Annu Rev Genet 48 (2014): 341–59. https://doi.org/10.1146/annurev-genet-120213-092015.
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  - Guo, Xiaoge, and Sue Jinks-Robertson. “Removal of N-6-methyladenine by the nucleotide excision repair pathway triggers the repair of mismatches in yeast gap-repair intermediates.” Dna Repair (Amst) 12, no. 12 (December 2013): 1053–61. https://doi.org/10.1016/j.dnarep.2013.09.006.
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  - Guo, Xiaoge, and Sue Jinks-Robertson. “Roles of exonucleases and translesion synthesis DNA polymerases during mitotic gap repair in yeast.” Dna Repair (Amst) 12, no. 12 (December 2013): 1024–30. https://doi.org/10.1016/j.dnarep.2013.10.001.
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  - Kim, Nayun, Jang-Eun Cho, Yue C. Li, and Sue Jinks-Robertson. “RNA∶DNA hybrids initiate quasi-palindrome-associated mutations in highly transcribed yeast DNA.” Plos Genet 9, no. 11 (November 2013): e1003924. https://doi.org/10.1371/journal.pgen.1003924.
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  - Jinks-Robertson, Sue, and Philip Hieter. “The 2013 Thomas Hunt Morgan Medal: Thomas Douglas Petes.” Genetics 194, no. 1 (May 2013): 1–4. https://doi.org/10.1534/genetics.113.150664.
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  - Boiteux, Serge, and Sue Jinks-Robertson. “DNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiae.” Genetics 193, no. 4 (April 2013): 1025–64. https://doi.org/10.1534/genetics.112.145219.
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  - Kozmin, Stanislav G., and Sue Jinks-Robertson. “The mechanism of nucleotide excision repair-mediated UV-induced mutagenesis in nonproliferating cells.” Genetics 193, no. 3 (March 2013): 803–17. https://doi.org/10.1534/genetics.112.147421.
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  - Cho, Jang-Eun, Nayun Kim, Yue C. Li, and Sue Jinks-Robertson. “Two distinct mechanisms of Topoisomerase 1-dependent mutagenesis in yeast.” Dna Repair (Amst) 12, no. 3 (March 1, 2013): 205–11. https://doi.org/10.1016/j.dnarep.2012.12.004.
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  - Guo, X., and S. Jinks-Robertson. “Removal of N-6-methyladenine by the nucleotide excision repair pathway triggers the repair of mismatches in yeast gap-repair intermediates.” Dna Repair, 2013.
  - Mitchel, Katrina, Kevin Lehner, and Sue Jinks-Robertson. “Heteroduplex DNA position defines the roles of the Sgs1, Srs2, and Mph1 helicases in promoting distinct recombination outcomes.” Plos Genet 9, no. 3 (2013): e1003340. https://doi.org/10.1371/journal.pgen.1003340.
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  - Grogan, Dennis, and Sue Jinks-Robertson. “Formaldehyde-induced mutagenesis in Saccharomyces cerevisiae: molecular properties and the roles of repair and bypass systems.” Mutat Res 731, no. 1–2 (March 1, 2012): 92–98. https://doi.org/10.1016/j.mrfmmm.2011.12.004.
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  - Kim, Nayun, and Sue Jinks-Robertson. “Transcription as a source of genome instability.” Nat Rev Genet 13, no. 3 (February 14, 2012): 204–14. https://doi.org/10.1038/nrg3152.
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  - Lehner, Kevin, Sarah V. Mudrak, Brenda K. Minesinger, and Sue Jinks-Robertson. “Frameshift mutagenesis: the roles of primer-template misalignment and the nonhomologous end-joining pathway in Saccharomyces cerevisiae.” Genetics 190, no. 2 (February 2012): 501–10. https://doi.org/10.1534/genetics.111.134890.
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  - Kim, Nayun, Sarah V. Mudrak, and Sue Jinks-Robertson. “The dCMP transferase activity of yeast Rev1 is biologically relevant during the bypass of endogenously generated AP sites.” Dna Repair (Amst) 10, no. 12 (December 10, 2011): 1262–71. https://doi.org/10.1016/j.dnarep.2011.09.017.
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  - Kim, Nayun, and Sue Jinks-Robertson. “Guanine repeat-containing sequences confer transcription-dependent instability in an orientation-specific manner in yeast.” Dna Repair (Amst) 10, no. 9 (September 5, 2011): 953–60. https://doi.org/10.1016/j.dnarep.2011.07.002.
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  - Kim, Nayun, Shar-yin N. Huang, Jessica S. Williams, Yue C. Li, Alan B. Clark, Jang-Eun Cho, Thomas A. Kunkel, Yves Pommier, and Sue Jinks-Robertson. “Mutagenic processing of ribonucleotides in DNA by yeast topoisomerase I.” Science 332, no. 6037 (June 24, 2011): 1561–64. https://doi.org/10.1126/science.1205016.
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  - Lippert, Malcolm J., Nayun Kim, Jang-Eun Cho, Ryan P. Larson, Nathan E. Schoenly, Shannon H. O’Shea, and Sue Jinks-Robertson. “Role for topoisomerase 1 in transcription-associated mutagenesis in yeast.” Proc Natl Acad Sci U S A 108, no. 2 (January 11, 2011): 698–703. https://doi.org/10.1073/pnas.1012363108.
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  - Jinks-Robertson, S. “Seeking Resolution: Budding Yeast Enzymes Finally Make the Cut.” Molecular Cell 40, no. 6 (December 22, 2010): 858–59. https://doi.org/10.1016/j.molcel.2010.12.001.
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  - Kim, Nayun, and Sue Jinks-Robertson. “Abasic sites in the transcribed strand of yeast DNA are removed by transcription-coupled nucleotide excision repair.” Mol Cell Biol 30, no. 13 (July 2010): 3206–15. https://doi.org/10.1128/MCB.00308-10.
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  - Mitchel, Katrina, Hengshan Zhang, Caroline Welz-Voegele, and Sue Jinks-Robertson. “Molecular structures of crossover and noncrossover intermediates during gap repair in yeast: implications for recombination.” Mol Cell 38, no. 2 (April 23, 2010): 211–22. https://doi.org/10.1016/j.molcel.2010.02.028.
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  - Mudrak, Sarah V., Caroline Welz-Voegele, and Sue Jinks-Robertson. “The polymerase eta translesion synthesis DNA polymerase acts independently of the mismatch repair system to limit mutagenesis caused by 7,8-dihydro-8-oxoguanine in yeast.” Mol Cell Biol 29, no. 19 (October 2009): 5316–26. https://doi.org/10.1128/MCB.00422-09.
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  - Kim, Nayun, and Sue Jinks-Robertson. “dUTP incorporation into genomic DNA is linked to transcription in yeast.” Nature 459, no. 7250 (June 25, 2009): 1150–53. https://doi.org/10.1038/nature08033.
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  - Lehner, Kevin, and Sue Jinks-Robertson. “The mismatch repair system promotes DNA polymerase zeta-dependent translesion synthesis in yeast.” Proc Natl Acad Sci U S A 106, no. 14 (April 7, 2009): 5749–54. https://doi.org/10.1073/pnas.0812715106.
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  - Welz-Voegele, Caroline, and Sue Jinks-Robertson. “Sequence divergence impedes crossover more than noncrossover events during mitotic gap repair in yeast.” Genetics 179, no. 3 (July 2008): 1251–62. https://doi.org/10.1534/genetics.108.090233.
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  - Abdulovic, Amy L., Brenda K. Minesinger, and Sue Jinks-Robertson. “The effect of sequence context on spontaneous Polzeta-dependent mutagenesis in Saccharomyces cerevisiae.” Nucleic Acids Res 36, no. 6 (April 2008): 2082–93. https://doi.org/10.1093/nar/gkn054.
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  - Stone, Jana E., Regan Gealy Ozbirn, Thomas D. Petes, and Sue Jinks-Robertson. “Role of proliferating cell nuclear antigen interactions in the mismatch repair-dependent processing of mitotic and meiotic recombination intermediates in yeast.” Genetics 178, no. 3 (March 2008): 1221–36. https://doi.org/10.1534/genetics.107.085415.
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  - Abdulovic, Amy L., Brenda K. Minesinger, and Sue Jinks-Robertson. “Identification of a strand-related bias in the PCNA-mediated bypass of spontaneous lesions by yeast Poleta.” Dna Repair (Amst) 6, no. 9 (September 1, 2007): 1307–18. https://doi.org/10.1016/j.dnarep.2007.02.026.
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  - Kim, Nayun, Amy L. Abdulovic, Regan Gealy, Malcolm J. Lippert, and Sue Jinks-Robertson. “Transcription-associated mutagenesis in yeast is directly proportional to the level of gene expression and influenced by the direction of DNA replication.” Dna Repair (Amst) 6, no. 9 (September 1, 2007): 1285–96. https://doi.org/10.1016/j.dnarep.2007.02.023.
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  - Kow, Yoke W., Gaobin Bao, Jason W. Reeves, Sue Jinks-Robertson, and Gray F. Crouse. “Oligonucleotide transformation of yeast reveals mismatch repair complexes to be differentially active on DNA replication strands.” Proc Natl Acad Sci U S A 104, no. 27 (July 3, 2007): 11352–57. https://doi.org/10.1073/pnas.0704695104.
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  - Abdulovic, Amy, Nayun Kim, and Sue Jinks-Robertson. “Mutagenesis and the three R's in yeast.” Dna Repair (Amst) 5, no. 4 (April 8, 2006): 409–21. https://doi.org/10.1016/j.dnarep.2005.11.006.
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  - Abdulovic, Amy L., and Sue Jinks-Robertson. “The in vivo characterization of translesion synthesis across UV-induced lesions in Saccharomyces cerevisiae: insights into Pol zeta- and Pol eta-dependent frameshift mutagenesis.” Genetics 172, no. 3 (March 2006): 1487–98. https://doi.org/10.1534/genetics.105.052480.
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  - Minesinger, Brenda K., Amy L. Abdulovic, Tingwei M. Ou, and Sue Jinks-Robertson. “The effect of oxidative metabolism on spontaneous Pol zeta-dependent translesion synthesis in Saccharomyces cerevisiae.” Dna Repair (Amst) 5, no. 2 (February 3, 2006): 226–34. https://doi.org/10.1016/j.dnarep.2005.10.002.
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  - Sabbioneda, Simone, Brenda K. Minesinger, Michele Giannattasio, Paolo Plevani, Marco Muzi-Falconi, and Sue Jinks-Robertson. “The 9-1-1 checkpoint clamp physically interacts with polzeta and is partially required for spontaneous polzeta-dependent mutagenesis in Saccharomyces cerevisiae.” J Biol Chem 280, no. 46 (November 18, 2005): 38657–65. https://doi.org/10.1074/jbc.M507638200.
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  - Erdeniz, Naz, Sandra Dudley, Regan Gealy, Sue Jinks-Robertson, and R Michael Liskay. “Novel PMS1 alleles preferentially affect the repair of primer strand loops during DNA replication.” Mol Cell Biol 25, no. 21 (November 2005): 9221–31. https://doi.org/10.1128/MCB.25.21.9221-9231.2005.
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  - Minesinger, Brenda K., and Sue Jinks-Robertson. “Roles of RAD6 epistasis group members in spontaneous polzeta-dependent translesion synthesis in Saccharomyces cerevisiae.” Genetics 169, no. 4 (April 2005): 1939–55. https://doi.org/10.1534/genetics.104.033894.
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  - Kow, Yoke W., Gaobin Bao, Brenda Minesinger, Sue Jinks-Robertson, Wolfram Siede, Yu Lin Jiang, and Marc M. Greenberg. “Mutagenic effects of abasic and oxidized abasic lesions in Saccharomyces cerevisiae.” Nucleic Acids Res 33, no. 19 (2005): 6196–6202. https://doi.org/10.1093/nar/gki926.
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  - Spell, Rachelle Miller, and Sue Jinks-Robertson. “Examination of the roles of Sgs1 and Srs2 helicases in the enforcement of recombination fidelity in Saccharomyces cerevisiae.” Genetics 168, no. 4 (December 2004): 1855–65. https://doi.org/10.1534/genetics.104.032771.
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  - Freedman, Jennifer A., and Sue Jinks-Robertson. “Effects of mismatch repair and Hpr1 on transcription-stimulated mitotic recombination in the yeast Saccharomyces cerevisiae.” Dna Repair (Amst) 3, no. 11 (November 2, 2004): 1437–46. https://doi.org/10.1016/j.dnarep.2004.06.005.
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  - Lippert, Malcolm J., Jennifer A. Freedman, Melissa A. Barber, and Sue Jinks-Robertson. “Identification of a distinctive mutation spectrum associated with high levels of transcription in yeast.” Mol Cell Biol 24, no. 11 (June 2004): 4801–9. https://doi.org/10.1128/MCB.24.11.4801-4809.2004.
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  - Hanna, Michelle, Barbara L. Chow, Natalie J. Morey, Sue Jinks-Robertson, Paul W. Doetsch, and Wei Xiao. “Involvement of two endonuclease III homologs in the base excision repair pathway for the processing of DNA alkylation damage in Saccharomyces cerevisiae.” Dna Repair (Amst) 3, no. 1 (January 5, 2004): 51–59. https://doi.org/10.1016/j.dnarep.2003.09.005.
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  - Spell, Rachelle Miller, and Sue Jinks-Robertson. “Determination of mitotic recombination rates by fluctuation analysis in Saccharomyces cerevisiae.” Methods Mol Biol 262 (2004): 3–12. https://doi.org/10.1385/1-59259-761-0:003.
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  - Spell, Rachelle Miller, and Sue Jinks-Robertson. “Role of mismatch repair in the fidelity of RAD51- and RAD59-dependent recombination in Saccharomyces cerevisiae.” Genetics 165, no. 4 (December 2003): 1733–44. https://doi.org/10.1093/genetics/165.4.1733.
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  - Morey, Natalie J., Paul W. Doetsch, and Sue Jinks-Robertson. “Delineating the requirements for spontaneous DNA damage resistance pathways in genome maintenance and viability in Saccharomyces cerevisiae.” Genetics 164, no. 2 (June 2003): 443–55. https://doi.org/10.1093/genetics/164.2.443.
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  - Gragg, Hana, Brian D. Harfe, and Sue Jinks-Robertson. “Base composition of mononucleotide runs affects DNA polymerase slippage and removal of frameshift intermediates by mismatch repair in Saccharomyces cerevisiae.” Mol Cell Biol 22, no. 24 (December 2002): 8756–62. https://doi.org/10.1128/MCB.22.24.8756-8762.2002.
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  - Welz-Voegele, Caroline, Jana E. Stone, Phuoc T. Tran, Hutton M. Kearney, R Michael Liskay, Thomas D. Petes, and Sue Jinks-Robertson. “Alleles of the yeast Pms1 mismatch-repair gene that differentially affect recombination- and replication-related processes.” Genetics 162, no. 3 (November 2002): 1131–45. https://doi.org/10.1093/genetics/162.3.1131.
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  - Freedman, Jennifer A., and Sue Jinks-Robertson. “Genetic requirements for spontaneous and transcription-stimulated mitotic recombination in Saccharomyces cerevisiae.” Genetics 162, no. 1 (September 2002): 15–27. https://doi.org/10.1093/genetics/162.1.15.
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  - Jinks-Robertson, Sue. “The genome's best friend.” Nat Genet 31, no. 4 (August 2002): 331–32. https://doi.org/10.1038/ng936.
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  - Greene, C. N., and S. Jinks-Robertson. “Spontaneous frameshift mutations in Saccharomyces cerevisiae: accumulation during DNA replication and removal by proofreading and mismatch repair activities.” Genetics 159, no. 1 (September 2001): 65–75. https://doi.org/10.1093/genetics/159.1.65.
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  - Doetsch, P. W., N. J. Morey, R. L. Swanson, and S. Jinks-Robertson. “Yeast base excision repair: interconnections and networks.” Prog Nucleic Acid Res Mol Biol 68 (2001): 29–39. https://doi.org/10.1016/s0079-6603(01)68087-5.
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  - Harfe, B. D., and S. Jinks-Robertson. “DNA polymerase zeta introduces multiple mutations when bypassing spontaneous DNA damage in Saccharomyces cerevisiae.” Mol Cell 6, no. 6 (December 2000): 1491–99. https://doi.org/10.1016/s1097-2765(00)00145-3.
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  - Harfe, B. D., and S. Jinks-Robertson. “Sequence composition and context effects on the generation and repair of frameshift intermediates in mononucleotide runs in Saccharomyces cerevisiae.” Genetics 156, no. 2 (October 2000): 571–78. https://doi.org/10.1093/genetics/156.2.571.
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  - Saxe, D., A. Datta, and S. Jinks-Robertson. “Stimulation of mitotic recombination events by high levels of RNA polymerase II transcription in yeast.” Mol Cell Biol 20, no. 15 (August 2000): 5404–14. https://doi.org/10.1128/MCB.20.15.5404-5414.2000.
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  - Harfe, B. D., and S. Jinks-Robertson. “Mismatch repair proteins and mitotic genome stability.” Mutat Res 451, no. 1–2 (June 30, 2000): 151–67. https://doi.org/10.1016/s0027-5107(00)00047-6.
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  - Harfe, B. D., B. K. Minesinger, and S. Jinks-Robertson. “Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast.” Curr Biol 10, no. 3 (February 10, 2000): 145–48. https://doi.org/10.1016/s0960-9822(00)00314-6.
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  - Harfe, B. D., and S. Jinks-Robertson. “DNA mismatch repair and genetic instability.” Annu Rev Genet 34 (2000): 359–99. https://doi.org/10.1146/annurev.genet.34.1.359.
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  - Morey, N. J., C. N. Greene, and S. Jinks-Robertson. “Genetic analysis of transcription-associated mutation in Saccharomyces cerevisiae.” Genetics 154, no. 1 (January 2000): 109–20. https://doi.org/10.1093/genetics/154.1.109.
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  - Nicholson, A., M. Hendrix, S. Jinks-Robertson, and G. F. Crouse. “Regulation of mitotic homeologous recombination in yeast. Functions of mismatch repair and nucleotide excision repair genes.” Genetics 154, no. 1 (January 2000): 133–46. https://doi.org/10.1093/genetics/154.1.133.
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  - You, H. J., R. L. Swanson, C. Harrington, A. H. Corbett, S. Jinks-Robertson, S. Sentürker, S. S. Wallace, S. Boiteux, M. Dizdaroglu, and P. W. Doetsch. “Saccharomyces cerevisiae Ntg1p and Ntg2p: broad specificity N-glycosylases for the repair of oxidative DNA damage in the nucleus and mitochondria.” Biochemistry 38, no. 35 (August 31, 1999): 11298–306. https://doi.org/10.1021/bi991121i.
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  - Harfe, B. D., and S. Jinks-Robertson. “Removal of frameshift intermediates by mismatch repair proteins in Saccharomyces cerevisiae.” Mol Cell Biol 19, no. 7 (July 1999): 4766–73. https://doi.org/10.1128/MCB.19.7.4766.
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  - Chen, W., and S. Jinks-Robertson. “The role of the mismatch repair machinery in regulating mitotic and meiotic recombination between diverged sequences in yeast.” Genetics 151, no. 4 (April 1999): 1299–1313. https://doi.org/10.1093/genetics/151.4.1299.
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  - Swanson, R. L., N. J. Morey, P. W. Doetsch, and S. Jinks-Robertson. “Overlapping specificities of base excision repair, nucleotide excision repair, recombination, and translesion synthesis pathways for DNA base damage in Saccharomyces cerevisiae.” Mol Cell Biol 19, no. 4 (April 1999): 2929–35. https://doi.org/10.1128/MCB.19.4.2929.
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  - Greene, C. N., and S. Jinks-Robertson. “Comparison of spontaneous and adaptive mutation spectra in yeast.” Journal of Genetics 78, no. 1 (January 1, 1999): 51–55. https://doi.org/10.1007/BF02994703.
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  - Chen, W., and S. Jinks-Robertson. “Mismatch repair proteins regulate heteroduplex formation during mitotic recombination in yeast.” Mol Cell Biol 18, no. 11 (November 1998): 6525–37. https://doi.org/10.1128/MCB.18.11.6525.
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  - Datta, A., M. Hendrix, M. Lipsitch, and S. Jinks-Robertson. “Dual roles for DNA sequence identity and the mismatch repair system in the regulation of mitotic crossing-over in yeast.” Proc Natl Acad Sci U S A 94, no. 18 (September 2, 1997): 9757–62. https://doi.org/10.1073/pnas.94.18.9757.
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  - Greene, C. N., and S. Jinks-Robertson. “Frameshift intermediates in homopolymer runs are removed efficiently by yeast mismatch repair proteins.” Mol Cell Biol 17, no. 5 (May 1997): 2844–50. https://doi.org/10.1128/MCB.17.5.2844.
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  - Jinks-Robertson, S., S. Sayeed, and T. Murphy. “Meiotic crossing over between nonhomologous chromosomes affects chromosome segregation in yeast.” Genetics 146, no. 1 (May 1997): 69–78. https://doi.org/10.1093/genetics/146.1.69.
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  - Sia, E. A., S. Jinks-Robertson, and T. D. Petes. “Genetic control of microsatellite stability.” Mutat Res 383, no. 1 (January 31, 1997): 61–70. https://doi.org/10.1016/s0921-8777(96)00046-8.
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  - Wierdl, M., C. N. Greene, A. Datta, S. Jinks-Robertson, and T. D. Petes. “Destabilization of simple repetitive DNA sequences by transcription in yeast.” Genetics 143, no. 2 (June 1996): 713–21. https://doi.org/10.1093/genetics/143.2.713.
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  - Datta, A., A. Adjiri, L. New, G. F. Crouse, and S. Jinks Robertson. “Mitotic crossovers between diverged sequences are regulated by mismatch repair proteins in Saccaromyces cerevisiae.” Mol Cell Biol 16, no. 3 (March 1996): 1085–93. https://doi.org/10.1128/MCB.16.3.1085.
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  - Datta, A., and S. Jinks-Robertson. “Association of increased spontaneous mutation rates with high levels of transcription in yeast.” Science 268, no. 5217 (June 16, 1995): 1616–19. https://doi.org/10.1126/science.7777859.
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  - Jinks-Robertson, S., M. Michelitch, and S. Ramcharan. “Substrate length requirements for efficient mitotic recombination in Saccharomyces cerevisiae.” Mol Cell Biol 13, no. 7 (July 1993): 3937–50. https://doi.org/10.1128/mcb.13.7.3937-3950.1993.
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  - Fridovich-Keil, J. L., and S. Jinks-Robertson. “A yeast expression system for human galactose-1-phosphate uridylyltransferase.” Proc Natl Acad Sci U S A 90, no. 2 (January 15, 1993): 398–402. https://doi.org/10.1073/pnas.90.2.398.
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  - Jinks-Robertson, S., and T. D. Petes. “Experimental determination of rates of concerted evolution.” Methods Enzymol 224 (1993): 631–46. https://doi.org/10.1016/0076-6879(93)24047-x.
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  - Steele, D. F., and S. Jinks-Robertson. “Time-dependent mitotic recombination in Saccharomyces cerevisiae.” Curr Genet 23, no. 5–6 (1993): 423–29. https://doi.org/10.1007/BF00312629.
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  - Steele, D. F., and S. Jinks-Robertson. “An examination of adaptive reversion in Saccharomyces cerevisiae.” Genetics 132, no. 1 (September 1992): 9–21. https://doi.org/10.1093/genetics/132.1.9.
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  - Chua, P., and S. Jinks-Robertson. “Segregation of recombinant chromatids following mitotic crossing over in yeast.” Genetics 129, no. 2 (October 1991): 359–69. https://doi.org/10.1093/genetics/129.2.359.
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  - Morris, M. E., and S. Jinks-Robertson. “Nucleotide sequence of the LYS2 gene of Saccharomyces cerevisiae: homology to Bacillus brevis tyrocidine synthetase 1.” Gene 98, no. 1 (February 1, 1991): 141–45. https://doi.org/10.1016/0378-1119(91)90117-t.
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  - Steele, D. F., M. E. Morris, and S. Jinks-Robertson. “Allelic and ectopic interactions in recombination-defective yeast strains.” Genetics 127, no. 1 (January 1991): 53–60. https://doi.org/10.1093/genetics/127.1.53.
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  - Petes, T. D., P. Detloff, S. Jinks-Robertson, S. R. Judd, M. Kupiec, D. Nag, A. Stapleton, L. S. Symington, A. Vincent, and M. White. “Recombination in yeast and the recombinant DNA technology.” Genome 31, no. 2 (1989): 536–40. https://doi.org/10.1139/g89-102.
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  - Jinks-Robertson, S., and T. D. Petes. “MEIOTIC RECOMBINATION BETWEEN REPEATED GENES ON NONHOMOLOGOUS CHROMOSOMES.” 3 (December 1, 1987): 43–52.
  - Jinks-Robertson, S., and T. D. Petes. “Chromosomal translocations generated by high-frequency meiotic recombination between repeated yeast genes.” Genetics 114, no. 3 (November 1986): 731–52. https://doi.org/10.1093/genetics/114.3.731.
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  - Jinks-Robertson, S., and T. D. Petes. “High-frequency meiotic gene conversion between repeated genes on nonhomologous chromosomes in yeast.” Proc Natl Acad Sci U S A 82, no. 10 (May 1985): 3350–54. https://doi.org/10.1073/pnas.82.10.3350.
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  - Jinks-Robertson, S., R. L. Gourse, and M. Nomura. “Expression of rRNA and tRNA genes in Escherichia coli: evidence for feedback regulation by products of rRNA operons.” Cell 33, no. 3 (July 1983): 865–76. https://doi.org/10.1016/0092-8674(83)90029-6.
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  - Jinks-Robertson, S., and M. Nomura. “Ribosomal protein S4 acts in trans as a translational repressor to regulate expression of the alpha operon in Escherichia coli.” J Bacteriol 151, no. 1 (July 1982): 193–202. https://doi.org/10.1128/jb.151.1.193-202.1982.
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  - Jinks-Robertson, S., and M. Nomura. “Regulation of ribosomal protein synthesis in an Escherichia coli mutant missing ribosomal protein L1.” J Bacteriol 145, no. 3 (March 1981): 1445–47. https://doi.org/10.1128/jb.145.3.1445-1447.1981.
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- Book Sections
  - Gamble, Dionna, Yee Fang Hum, and Sue Jinks-Robertson. “High-Throughput Analysis of Heteroduplex DNA in Mitotic Recombination Products.,” 2153:503–19, 2021. https://doi.org/10.1007/978-1-0716-0644-5_34.
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  - Cho, Jang-Eun, and Sue Jinks-Robertson. “Topoisomerase I and Genome Stability: The Good and the Bad.,” 1703:21–45, 2018. https://doi.org/10.1007/978-1-4939-7459-7_2.
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- Preprints
  - Shaltz, Samantha, and Sue Jinks-Robertson. “Genetic control of the error-prone repair of a chromosomal double-strand break with 5' overhangs in yeast.,” May 4, 2023. https://doi.org/10.1101/2023.05.04.539391.
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  - Gusa, Asiya, Vikas Yadav, Cullen Roth, Jonathan D. Williams, Eva Mei Shouse, Paul Magwene, Joseph Heitman, and Sue Jinks-Robertson. “Genome-wide analysis of heat stress-stimulated transposon mobility in the human fungal pathogen Cryptococcus deneoformans.” Cold Spring Harbor Laboratory, June 10, 2022. https://doi.org/10.1101/2022.06.10.495668.
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- MGM 293: Research Independent Study I 2023
- MGM 293: Research Independent Study I 2022
- MGM 593: Research Independent Study 2022
- MGM 293: Research Independent Study I 2021
- MGM 593: Research Independent Study 2021

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