Lesley H. Curtis
Professor in Population Health Sciences

Lesley H. Curtis, PhD, is Professor in Medicine, directs the Center for Population Health Sciences in the Duke University School of Medicine, and directs the Center for Pragmatic Health Systems Research in the Duke Clinical Research Institute.

A health services researcher by training, Dr. Curtis oversees a portfolio of projects that use observational data to address questions related to clinical and comparative effectiveness, pharmacoepidemiology, health care delivery, and epidemiological trends across a broad array of clinical conditions and clinical care settings. An expert in the use of Medicare claims data for health services and clinical outcomes research, she has led the linkage of Medicare claims with several large clinical registries and epidemiological cohort studies including the Framingham Heart Study and the Cardiovascular Health Study.

Dr. Curtis serves on the American Heart Association/American College of Cardiology Task Force on Practice Guidelines and on the American Heart Association’s Task Force on Performance Measures, working to continuously improve the incorporation of evidence into health care delivery. Additionally, she serves as Co-Lead of the Data Core for the FDA’s Sentinel Initiative, Co-PI of the NIH Health Care Systems Collaboratory, and Lead of the Distributed Research Network Operations Center for PCORI’s National Clinical Research Network (PCORnet), working with health systems and patient networks to develop a harmonized data infrastructure for robust observational and interventional research.

Areas of expertise: Health Services Research and Health Policy


Current Appointments & Affiliations

Contact Information

  • 2200 West Main Street, Suite 720-A, Erwin Square Building, Durham, NC 27705
  • Duke Box 104023, Durham, NC 27708

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