Karen Patton Alexander | Scholars@Duke

Karen Patton Alexander
Professor of Medicine

My research focus is on cardiovascular disease management and outcomes in special populations, specifically older adults. Historically there has been a lack of randomized controlled data regarding treatment efficacy and outcomes in this growing population. Because of this, certain therapies may have different risk benefit profiles, which may cause physicians to alter their therapeutic interventions. My research explores evidence based treatment for older adults, including preferences and decision-making as well as frailty and aging assessments in clinical trials and registries. Diagnosis and management of stable ischemic heart disease is also an area of focus.

Current Appointments & Affiliations

Professor of Medicine, Medicine, Cardiology, Medicine 2015
Member in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 1995

Contact Information

2400 Pratt St Ste 7068, Durham, NC 27705
Duke Box 3411, Durham, NC 27710
(919) 668-8871

Background
Education, Training, & Certifications
- Cardiology Fellow, Medicine, Duke University 1995 - 1998
- Resident, Internal Medicine, Brigham and Women's Hospital 1993 - 1995
- Intern, Internal Medicine, Brigham and Women's Hospital 1992 - 1993
- M.D., Duke University 1992
Duke Appointment History
- Associate Professor of Medicine, Medicine, Cardiology, Medicine 2010 - 2015
- Associate Professor of Medicine, Medicine, Cardiology, Medicine 2006 - 2010
- Assistant Professor of Medicine, Medicine, Cardiology, Medicine 2000 - 2006
- Associate in the Department of Medicine, Medicine, Cardiology, Medicine 1998 - 2000
- Instructor, Temporary in the Department of Medicine, Medicine, Cardiology, Medicine 1998
Recognition
In the News
- NOV 10, 2015
  
  Angioplasty Procedure Reduces Need for Additional Drug Even When Blockages Remain
Research
Selected Grants
- ISCHEMIA-CKD SDCC awarded by National Institutes of Health 2013 - 2019
- The ISCHEMIA Trial - SDCC awarded by National Institutes of Health 2011 - 2019
- The ISCHEMIA Trial - SDCC awarded by National Institutes of Health 2011 - 2019
- CABANA-AF Trial awarded by National Institutes of Health 2009 - 2017
- NCDR-ACTION awarded by American College of Cardiology Foundation 2008 - 2015
- Duke Cardiovascular CERTs awarded by Agency for Healthcare Research and Quality 2007 - 2012
- Transition of Care for Acute Stroke and Myocardial Infarction Patients awarded by Agency for Healthcare Research and Quality 2010 - 2011
- Safer Antithrombotic Therapy for Elderly ACS Patients awarded by National Institutes of Health 2005 - 2008
- Managed Care Features Affecting Quality for CAD Patients awarded by National Institutes of Health 1999 - 2003
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Dodson, John A., Alexandra M. Hajduk, Terrence E. Murphy, Mary Geda, Harlan M. Krumholz, Sui Tsang, Michael G. Nanna, et al. “Thirty-Day Readmission Risk Model for Older Adults Hospitalized With Acute Myocardial Infarction..” Circ Cardiovasc Qual Outcomes 12, no. 5 (May 2019). https://doi.org/10.1161/CIRCOUTCOMES.118.005320.
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  - Fanaroff, Alexander C., Kristi Prather, Amanda Brucker, Daniel Wojdyla, Linda Davidson-Ray, Daniel B. Mark, Redford B. Williams, et al. “Relationship Between Optimism and Outcomes in Patients With Chronic Angina Pectoris..” Am J Cardiol 123, no. 9 (May 1, 2019): 1399–1405. https://doi.org/10.1016/j.amjcard.2019.01.036.
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  - Kaul, Padma, Karen P. Alexander, E Magnus Ohman, Anamaria Savu, Matthew T. Roe, Shaun G. Goodman, Keith A. Fox, et al. “Sex And Prognostic Significance of Self-Reported Frailty in Non-ST-Segment Elevation Acute Coronary Syndromes: Insights From the TRILOGY ACS Trial..” The Canadian Journal of Cardiology 35, no. 4 (April 2019): 430–37. https://doi.org/10.1016/j.cjca.2018.12.035.
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  - Hochman, Judith S., Harmony R. Reynolds, Sripal Bangalore, Sean M. O’Brien, Karen P. Alexander, Roxy Senior, William E. Boden, et al. “Baseline Characteristics and Risk Profiles of Participants in the ISCHEMIA Randomized Clinical Trial..” Jama Cardiology, February 27, 2019. https://doi.org/10.1001/jamacardio.2019.0014.
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  - Alexander, Karen P., Marc A. Brouwer, Hillary Mulder, Dragos Vinereanu, Renato D. Lopes, Marco Proietti, Sana M. Al-Khatib, et al. “Outcomes of apixaban versus warfarin in patients with atrial fibrillation and multi-morbidity: Insights from the ARISTOTLE trial..” American Heart Journal 208 (February 2019): 123–31. https://doi.org/10.1016/j.ahj.2018.09.017.
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  - Fanaroff, Alexander C., Robert Clare, Karen S. Pieper, Kenneth W. Mahaffey, Chiara Melloni, Jennifer B. Green, John H. Alexander, et al. “Frequency, Regional Variation, and Predictors of Undetermined Cause of Death in Cardiometabolic Clinical Trials: A Pooled Analysis of 9259 Deaths in 9 Trials..” Circulation 139, no. 7 (February 2019): 863–73. https://doi.org/10.1161/circulationaha.118.037202.
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  - Afilalo, Jonathan, Abhinav Sharma, Shuaiqi Zhang, J Matthew Brennan, Fred H. Edwards, Michael J. Mack, James B. McClurken, et al. “Gait Speed and 1-Year Mortality Following Cardiac Surgery: A Landmark Analysis From the Society of Thoracic Surgeons Adult Cardiac Surgery Database..” Journal of the American Heart Association 7, no. 23 (December 2018). https://doi.org/10.1161/JAHA.118.010139.
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  - Dodson, John A., Judith S. Hochman, Matthew T. Roe, Anita Y. Chen, Sarwat I. Chaudhry, Stuart Katz, Hua Zhong, et al. “The Association of Frailty With In-Hospital Bleeding Among Older Adults With Acute Myocardial Infarction: Insights From the ACTION Registry..” Jacc. Cardiovascular Interventions 11, no. 22 (November 2018): 2287–96. https://doi.org/10.1016/j.jcin.2018.08.028.
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  - Hernandez, Adrian F., Jennifer B. Green, Salim Janmohamed, Ralph B. D’Agostino, Christopher B. Granger, Nigel P. Jones, Lawrence A. Leiter, et al. “Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial..” Lancet (London, England) 392, no. 10157 (October 2, 2018): 1519–29. https://doi.org/10.1016/s0140-6736(18)32261-x.
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  - Krishnaswami, Ashok, Dae Hyun Kim, Charles E. McCulloch, Daniel E. Forman, Mathew S. Maurer, Karen P. Alexander, and Michael W. Rich. “Individual and Joint Effects of Pulse Pressure and Blood Pressure Treatment Intensity on Serious Adverse Events in the SPRINT Trial..” The American Journal of Medicine 131, no. 10 (October 2018): 1220-1227.e1. https://doi.org/10.1016/j.amjmed.2018.05.027.
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  - Patel, Ashish, Shaun G. Goodman, Andrew T. Yan, Karen P. Alexander, Camilla L. Wong, Asim N. Cheema, Jacob A. Udell, et al. “Frailty and Outcomes After Myocardial Infarction: Insights From the CONCORDANCE Registry..” Journal of the American Heart Association 7, no. 18 (September 2018). https://doi.org/10.1161/JAHA.118.009859.
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  - Bangalore, Sripal, David J. Maron, Jerome L. Fleg, Sean M. O’Brien, Charles A. Herzog, Gregg W. Stone, Daniel B. Mark, et al. “International Study of Comparative Health Effectiveness with Medical and Invasive Approaches-Chronic Kidney Disease (ISCHEMIA-CKD): Rationale and design..” American Heart Journal 205 (August 2018): 42–52. https://doi.org/10.1016/j.ahj.2018.07.023.
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  - ISCHEMIA Trial Research Group, Yves, David J. Maron, Judith S. Hochman, Sean M. O’Brien, Harmony R. Reynolds, William E. Boden, Gregg W. Stone, et al. “International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA) trial: Rationale and design..” Am Heart J 201 (July 2018): 124–35. https://doi.org/10.1016/j.ahj.2018.04.011.
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  - Miller, A. P., M. Maurer, and K. P. Alexander. “Geriatric Cardiology: Two Decades of Progress and Strategy for the Future.” Journal of the American College of Cardiology 71, no. 25 (June 26, 2018): 2970–73. https://doi.org/10.1016/j.jacc.2018.05.014.
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  - Bangalore, Sripal, David J. Maron, Harmony R. Reynolds, Gregg W. Stone, Sean M. O’Brien, Karen P. Alexander, and Judith S. Hochman. “ISCHEMIA: Establishing the Primary End Point..” Circ Cardiovasc Qual Outcomes 11, no. 5 (May 2018). https://doi.org/10.1161/CIRCOUTCOMES.118.004791.
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  - Gorodeski, Eiran Z., Parag Goyal, Scott L. Hummel, Ashok Krishnaswami, Sarah J. Goodlin, Linda L. Hart, Daniel E. Forman, et al. “Domain Management Approach to Heart Failure in the Geriatric Patient: Present and Future..” J Am Coll Cardiol 71, no. 17 (May 1, 2018): 1921–36. https://doi.org/10.1016/j.jacc.2018.02.059.
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  - Madhavan, Mahesh V., Bernard J. Gersh, Karen P. Alexander, Christopher B. Granger, and Gregg W. Stone. “Coronary Artery Disease in Patients ≥80 Years of Age..” Journal of the American College of Cardiology 71, no. 18 (May 2018): 2015–40. https://doi.org/10.1016/j.jacc.2017.12.068.
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  - Patel, Krishna K., Suzanne V. Arnold, Philip G. Jones, Mohammed Qintar, Karen P. Alexander, and John A. Spertus. “Relation of Age and Health-Related Quality of Life to Invasive Versus Ischemia-Guided Management of Patients with Non-ST Elevation Myocardial Infarction..” The American Journal of Cardiology 121, no. 7 (April 2018): 789–95. https://doi.org/10.1016/j.amjcard.2017.12.034.
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  - Flint, Kelsey, Kevin Kennedy, Suzanne V. Arnold, John A. Dodson, Sharon Cresci, and Karen P. Alexander. “Slow Gait Speed and Cardiac Rehabilitation Participation in Older Adults After Acute Myocardial Infarction..” Journal of the American Heart Association 7, no. 5 (February 24, 2018). https://doi.org/10.1161/JAHA.117.008296.
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  - Guimarães, Patrícia O., Sergio Leonardi, Zhen Huang, Lars Wallentin, Frans Van de Werf, Philip E. Aylward, Claes Held, et al. “Clinical features and outcomes of patients with type 2 myocardial infarction: Insights from the Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRACER) trial..” American Heart Journal 196 (February 2018): 28–35. https://doi.org/10.1016/j.ahj.2017.10.007.
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  - Cooper, Lauren B., Bradley G. Hammill, Larry A. Allen, JoAnn Lindenfeld, Robert J. Mentz, Joseph G. Rogers, Carmelo A. Milano, Chetan B. Patel, Karen P. Alexander, and Adrian F. Hernandez. “Assessing Frailty in Patients Undergoing Destination Therapy Left Ventricular Assist Device: Observations from Interagency Registry for Mechanically Assisted Circulatory Support..” Asaio Journal (American Society for Artificial Internal Organs : 1992) 64, no. 1 (January 2018): 16–23. https://doi.org/10.1097/mat.0000000000000600.
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  - Krishnaswami, Ashok, Mathew S. Maurer, and Karen P. Alexander. “Contextualizing Myocardial Infarction: Comorbidities and Priorities in Older Adults..” The American Journal of Medicine 130, no. 10 (October 2017): 1144–47. https://doi.org/10.1016/j.amjmed.2017.05.043.
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  - Alexander, Karen P. “Walking as a Window to Risk and Resiliency..” Circulation 136, no. 7 (August 2017): 644–45. https://doi.org/10.1161/circulationaha.117.028889.
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  - Bagai, Akshay, Karen P. Alexander, Jeffrey S. Berger, Roxy Senior, Chakkanalil Sajeev, Radoslaw Pracon, Kreton Mavromatis, et al. “Use of troponin assay 99th percentile as the decision level for myocardial infarction diagnosis..” American Heart Journal 190 (August 2017): 135–39. https://doi.org/10.1016/j.ahj.2017.04.016.
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  - Neeland, Ian J., Sandeep R. Das, DaJuanicia N. Simon, Deborah B. Diercks, Karen P. Alexander, Tracy Y. Wang, and James A. de Lemos. “The obesity paradox, extreme obesity, and long-term outcomes in older adults with ST-segment elevation myocardial infarction: results from the NCDR..” European Heart Journal. Quality of Care & Clinical Outcomes 3, no. 3 (July 2017): 183–91. https://doi.org/10.1093/ehjqcco/qcx010.
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  - Posenau, J Trevor, Daniel M. Wojdyla, Linda K. Shaw, Karen P. Alexander, E Magnus Ohman, Manesh R. Patel, Peter K. Smith, and Sunil V. Rao. “Revascularization Strategies and Outcomes in Elderly Patients With Multivessel Coronary Disease..” Ann Thorac Surg 104, no. 1 (July 2017): 107–15. https://doi.org/10.1016/j.athoracsur.2016.10.053.
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  - Alexander, Karen P. “Low-Hanging Fruit for a Healthy Old Age..” Journal of the American College of Cardiology 69, no. 25 (June 2017): 3027–28. https://doi.org/10.1016/j.jacc.2017.05.025.
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  - Fanaroff, Alexander C., Stefan K. James, Giora Weisz, Kristi Prather, Kevin J. Anstrom, Daniel B. Mark, Ori Ben-Yehuda, Karen P. Alexander, Gregg W. Stone, and E Magnus Ohman. “Ranolazine After Incomplete Percutaneous Coronary Revascularization in Patients With Versus Without Diabetes Mellitus: RIVER-PCI Trial..” Journal of the American College of Cardiology 69, no. 18 (May 2017): 2304–13. https://doi.org/10.1016/j.jacc.2017.02.056.
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  - Guimarães, Patrícia O., Renato D. Lopes, Susanna R. Stevens, André Zimerman, Lisa Wruck, Stefan K. James, Ghazala Haque, Roberto Rocha C. V. Giraldez, John H. Alexander, and Karen P. Alexander. “Reporting Clinical End Points and Safety Events in an Acute Coronary Syndrome Trial: Results With Integrated Collection..” Journal of the American Heart Association 6, no. 4 (April 24, 2017). https://doi.org/10.1161/JAHA.117.005490.
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  - Alexander, Karen P. “Assessing the Utility of Transcatheter Aortic Valve Replacement..” Jama Cardiology 2, no. 4 (April 2017): 416–17. https://doi.org/10.1001/jamacardio.2016.5549.
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  - Sharma, Abhinav, and Karen P. Alexander. “Natriuretic Peptides in Older Patients With Heart Failure: A Look Into the Seeds of Time..” Journal of the American Geriatrics Society 65, no. 4 (April 2017): 691–92. https://doi.org/10.1111/jgs.14762.
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  - Otto, C. M., D. J. Kumbhani, K. P. Alexander, J. H. Calhoon, M. Y. Desai, S. Kaul, J. C. Lee, C. E. Ruiz, and C. M. Vassileva. “2017 ACC Expert Consensus Decision Pathway for Transcatheter Aortic Valve Replacement in the Management of Adults With Aortic Stenosis: A Report of the American College of Cardiology Task Force on Clinical Expert Consensus Documents.” Journal of the American College of Cardiology 69, no. 10 (March 14, 2017): 1313–46. https://doi.org/10.1016/j.jacc.2016.12.006.
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  - Alexander, Karen P. “Putting the Acute Coronary Syndrome in Context After 80 Years of Age..” Circulation 135, no. 1 (January 2017): 5–6. https://doi.org/10.1161/circulationaha.116.022148.
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  - Alexander, Karen P. “Identifying the frailty phenotype: The evidence for good enough..” American Heart Journal 182 (December 2016): 144–45. https://doi.org/10.1016/j.ahj.2016.09.005.
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  - Rich, Michael W., Deborah A. Chyun, Adam H. Skolnick, Karen P. Alexander, Daniel E. Forman, Dalane W. Kitzman, Mathew S. Maurer, et al. “Knowledge Gaps in Cardiovascular Care of Older Adults: A Scientific Statement from the American Heart Association, American College of Cardiology, and American Geriatrics Society: Executive Summary..” Journal of the American Geriatrics Society 64, no. 11 (November 2016): 2185–92. https://doi.org/10.1111/jgs.14576.
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  - Alexander, Karen P., Michael W. Rich, Daniel E. Forman, Nanette K. Wenger, John A. Dodson, Joseph S. Alpert, James N. Kirkpatrick, and Mathew S. Maurer. “Top 10 List for the Cardiovascular Care of Older Adults..” The American Journal of Medicine 129, no. 9 (September 2016): 901–2. https://doi.org/10.1016/j.amjmed.2016.04.031.
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  - Arnold, Suzanne V., Anna Grodzinsky, Kensey L. Gosch, Mikhail Kosiborod, Philip G. Jones, Tracie Breeding, Arooge Towheed, John Beltrame, Karen P. Alexander, and John A. Spertus. “Predictors of Physician Under-Recognition of Angina in Outpatients With Stable Coronary Artery Disease..” Circulation. Cardiovascular Quality and Outcomes 9, no. 5 (September 2016): 554–59. https://doi.org/10.1161/CIRCOUTCOMES.116.002781.
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  - Forman, Daniel E., and Karen P. Alexander. “Frailty: A Vital Sign for Older Adults With Cardiovascular Disease..” The Canadian Journal of Cardiology 32, no. 9 (September 2016): 1082–87. https://doi.org/10.1016/j.cjca.2016.05.015.
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  - Armaganijan, Luciana V., Karen P. Alexander, Zhen Huang, Pierluigi Tricoci, Claes Held, Frans Van de Werf, Paul W. Armstrong, et al. “Effect of age on efficacy and safety of vorapaxar in patients with non-ST-segment elevation acute coronary syndrome: Insights from the Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRACER) trial..” American Heart Journal 178 (August 2016): 176–84. https://doi.org/10.1016/j.ahj.2016.05.012.
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  - Wayangankar, S. A., M. T. Roe, A. Y. Chen, R. S. Gupta, R. P. Giugliano, L. K. Newby, J. A. de Lemos, K. P. Alexander, T. A. Sanborn, and J. F. Saucedo. “Trends in use of anti-thrombotic agents and outcomes in patients with non-ST-segment elevation myocardial infarction (NSTEMI) managed with an invasive strategy..” Indian Heart Journal 68, no. 4 (July 2016): 464–72. https://doi.org/10.1016/j.ihj.2015.09.036.
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  - Afilalo, Jonathan, Sunghee Kim, Sean O’Brien, J Matthew Brennan, Fred H. Edwards, Michael J. Mack, James B. McClurken, et al. “Gait Speed and Operative Mortality in Older Adults Following Cardiac Surgery..” Jama Cardiol 1, no. 3 (June 1, 2016): 314–21. https://doi.org/10.1001/jamacardio.2016.0316.
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  - White, Harvey D., Cynthia M. Westerhout, Karen P. Alexander, Matthew T. Roe, Kenneth J. Winters, Derek D. Cyr, Keith Aa Fox, et al. “Frailty is associated with worse outcomes in non-ST-segment elevation acute coronary syndromes: Insights from the TaRgeted platelet Inhibition to cLarify the Optimal strateGy to medicallY manage Acute Coronary Syndromes (TRILOGY ACS) trial..” European Heart Journal. Acute Cardiovascular Care 5, no. 3 (June 2016): 231–42. https://doi.org/10.1177/2048872615581502.
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  - Alfredsson, Joakim, and Karen P. Alexander. “Multiple Chronic Conditions in Older Adults with Acute Coronary Syndromes..” Clin Geriatr Med 32, no. 2 (May 2016): 291–303. https://doi.org/10.1016/j.cger.2016.01.009.
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  - Rich, Michael W., Deborah A. Chyun, Adam H. Skolnick, Karen P. Alexander, Daniel E. Forman, Dalane W. Kitzman, Mathew S. Maurer, et al. “Knowledge Gaps in Cardiovascular Care of the Older Adult Population: A Scientific Statement From the American Heart Association, American College of Cardiology, and American Geriatrics Society..” Journal of the American College of Cardiology 67, no. 20 (May 2016): 2419–40. https://doi.org/10.1016/j.jacc.2016.03.004.
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  - Rich, Michael W., Deborah A. Chyun, Adam H. Skolnick, Karen P. Alexander, Daniel E. Forman, Dalane W. Kitzman, Mathew S. Maurer, et al. “Knowledge Gaps in Cardiovascular Care of the Older Adult Population: A Scientific Statement From the American Heart Association, American College of Cardiology, and American Geriatrics Society..” Circulation 133, no. 21 (May 2016): 2103–22. https://doi.org/10.1161/cir.0000000000000380.
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  - Kragholm, Kristian, Sarah A. Goldstein, Qinghong Yang, Renato D. Lopes, Phillip J. Schulte, Gwen M. Bernacki, Harvey D. White, et al. “Trends in Enrollment, Clinical Characteristics, Treatment, and Outcomes According to Age in Non-ST-Segment-Elevation Acute Coronary Syndromes Clinical Trials.” Circulation 133, no. 16 (April 19, 2016): 1560-+. https://doi.org/10.1161/CIRCULATIONAHA.115.017299.
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  - Alfredsson, Joakim, Amanda Stebbins, J Matthew Brennan, Roland Matsouaka, Jonathan Afilalo, Eric D. Peterson, Sreekanth Vemulapalli, et al. “Gait Speed Predicts 30-Day Mortality After Transcatheter Aortic Valve Replacement: Results From the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry..” Circulation 133, no. 14 (April 5, 2016): 1351–59. https://doi.org/10.1161/CIRCULATIONAHA.115.020279.
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  - Kragholm, Kristian, Sarah A. Goldstein, Qinghong Yang, Renato D. Lopes, Phillip J. Schulte, Gwen M. Bernacki, Harvey D. White, et al. “Trends in Enrollment, Clinical Characteristics, Treatment, and Outcomes According to Age in Non-ST-Segment-Elevation Acute Coronary Syndromes Clinical Trials..” Circulation 133, no. 16 (April 2016): 1560–73. https://doi.org/10.1161/CIRCULATIONAHA.115.017299.
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  - Melloni, Chiara, and Karen P. Alexander. “Exploring the Nexus Between Chronic Kidney Disease and Cardiovascular Disease..” European Heart Journal. Quality of Care & Clinical Outcomes 2, no. 2 (April 2016): 62–63. https://doi.org/10.1093/ehjqcco/qcw009.
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  - Zimerman, André, Renato D. Lopes, Amanda L. Stebbins, Patrícia O. Guimarães, Ghazala Haque, Chiara Melloni, Kathleen Trollinger, et al. “Pooled analysis of adverse event collection from 4 acute coronary syndrome trials..” American Heart Journal 174 (April 2016): 60–67. https://doi.org/10.1016/j.ahj.2016.01.003.
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  - Dodson, John A., Suzanne V. Arnold, Kensey L. Gosch, Thomas M. Gill, John A. Spertus, Harlan M. Krumholz, Michael W. Rich, et al. “Slow Gait Speed and Risk of Mortality or Hospital Readmission After Myocardial Infarction in the Translational Research Investigating Underlying Disparities in Recovery from Acute Myocardial Infarction: Patients' Health Status Registry..” Journal of the American Geriatrics Society 64, no. 3 (March 2016): 596–601. https://doi.org/10.1111/jgs.14016.
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  - Dai, Xuming, Jan Busby-Whitehead, Daniel E. Forman, and Karen P. Alexander. “Stable ischemic heart disease in the older adults..” Journal of Geriatric Cardiology : Jgc 13, no. 2 (February 2016): 109–14. https://doi.org/10.11909/j.issn.1671-5411.2016.02.013.
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  - Dai, Xuming, Jan Busby-Whitehead, and Karen P. Alexander. “Acute coronary syndrome in the older adults..” Journal of Geriatric Cardiology : Jgc 13, no. 2 (February 2016): 101–8. https://doi.org/10.11909/j.issn.1671-5411.2016.02.012.
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  - Forman, Daniel E., Karen Alexander, Ralph G. Brindis, Anne B. Curtis, Mathew Maurer, Michael W. Rich, Laurence Sperling, and Nanette K. Wenger. “Improved Cardiovascular Disease Outcomes in Older Adults..” F1000research 5 (January 28, 2016). https://doi.org/10.12688/f1000research.7088.1.
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  - Weisz, Giora, Philippe Généreux, Andres Iñiguez, Aleksander Zurakowski, Michael Shechter, Karen P. Alexander, Ovidiu Dressler, et al. “Ranolazine in patients with incomplete revascularisation after percutaneous coronary intervention (RIVER-PCI): a multicentre, randomised, double-blind, placebo-controlled trial..” Lancet 387, no. 10014 (January 9, 2016): 136–45. https://doi.org/10.1016/S0140-6736(15)00459-6.
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  - Alexander, Karen P., Giora Weisz, Kristi Prather, Stefan James, Daniel B. Mark, Kevin J. Anstrom, Linda Davidson-Ray, et al. “Effects of Ranolazine on Angina and Quality of Life After Percutaneous Coronary Intervention With Incomplete Revascularization: Results From the Ranolazine for Incomplete Vessel Revascularization (RIVER-PCI) Trial..” Circulation 133, no. 1 (January 5, 2016): 39–47. https://doi.org/10.1161/CIRCULATIONAHA.115.019768.
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  - Alexander, Karen P., Olena Stadnyuk, Suzanne V. Arnold, Daniel B. Mark, E Magnus Ohman, and Kevin J. Anstrom. “Assessing Quality of Life and Medical Care in Chronic Angina: An Internet Survey..” Interactive Journal of Medical Research 5, no. 2 (January 2016). https://doi.org/10.2196/ijmr.4971.
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  - Qintar, Mohammed, John A. Spertus, Kensey L. Gosch, John Beltrame, Faraz Kureshi, Ali Shafiq, Tracie Breeding, Karen P. Alexander, and Suzanne V. Arnold. “Effect of angina under-recognition on treatment in outpatients with stable ischaemic heart disease..” European Heart Journal. Quality of Care & Clinical Outcomes 2, no. 3 (January 2016): 208–14. https://doi.org/10.1093/ehjqcco/qcw016.
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  - Kang, Hyun-Jae, DaJuanicia Simon, Tracy Y. Wang, Karen P. Alexander, Myung Ho Jeong, Hyo-Soo Kim, Eric R. Bates, et al. “The Contemporary Use of Angiography and Revascularization Among Patients With Non-ST-Segment Elevation Myocardial Infarction in the United States Compared With South Korea.” Clinical Cardiology 38, no. 12 (December 2015): 708–14. https://doi.org/10.1002/clc.22475.
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  - Kang, Hyun-Jae, Dajuanicia Simon, Tracy Y. Wang, Karen P. Alexander, Myung Ho Jeong, Hyo-Soo Kim, Eric R. Bates, et al. “The Contemporary Use of Angiography and Revascularization Among Patients With Non-ST-Segment Elevation Myocardial Infarction in the United States Compared With South Korea..” Clinical Cardiology 38, no. 12 (December 2015): 708–14. https://doi.org/10.1002/clc.22475.
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  - Shen, Lan, Bimal R. Shah, Shuang Li, Laine Thomas, Tracy Y. Wang, Karen P. Alexander, Eric D. Peterson, Ben He, and Matthew T. Roe. “The Association of Transfer Rate From Hospitals Without Revascularization Capabilities and Mortality Risk for Older Non-ST-Segment Elevation Myocardial Infarction Patients..” Clinical Cardiology 38, no. 12 (December 2015): 733–39. https://doi.org/10.1002/clc.22480.
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  - Skolnick, Adam H., and Karen P. Alexander. “Older Adults in Clinical Research and Drug Development: Closing the Geriatric Gap..” Circulation. Cardiovascular Quality and Outcomes 8, no. 6 (November 2015): 631–33. https://doi.org/10.1161/circoutcomes.115.002158.
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  - Swiger, K. J., S. S. Martin, F. Tang, M. J. Blaha, R. S. Blumenthal, K. P. Alexander, S. V. Arnold, and J. A. Spertus. “Cognitive and Physical Function by Statin Exposure in Elderly Individuals Following Acute Myocardial Infarction.” Clinical Cardiology 38, no. 8 (August 1, 2015): 455–61. https://doi.org/10.1002/clc.22423.
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  - Swiger, Kristopher J., Seth S. Martin, Fengming Tang, Michael J. Blaha, Roger S. Blumenthal, Karen P. Alexander, Suzanne V. Arnold, and John A. Spertus. “Cognitive and Physical Function by Statin Exposure in Elderly Individuals Following Acute Myocardial Infarction..” Clinical Cardiology 38, no. 8 (August 2015): 455–61. https://doi.org/10.1002/clc.22423.
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  - Cavender, Matthew A., Karen P. Alexander, Samuel Broderick, Linda K. Shaw, Charles B. McCants, Judith Kempf, and E Magnus Ohman. “Long-term morbidity and mortality among medically managed patients with angina and multivessel coronary artery disease..” American Heart Journal 158, no. 6 (December 2009): 933–40. https://doi.org/10.1016/j.ahj.2009.10.013.
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  - Gharacholou, S. M., and K. P. Alexander. “Evolving role of revascularization in older adults with acute coronary syndrome.” Current Cardiovascular Risk Reports 3, no. 5 (December 1, 2009): 355–65. https://doi.org/10.1007/s12170-009-0052-5.
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  - Ali, Robin C., Chiara Melloni, Fang-Shu Ou, Kenneth Schmader, E Magnus Ohman, Matthew T. Roe, Eric D. Peterson, and Karen P. Alexander. “Age and persistent use of cardiovascular medication after acute coronary syndrome: results from medication applied and sustained over time..” Journal of the American Geriatrics Society 57, no. 11 (November 2009): 1990–96. https://doi.org/10.1111/j.1532-5415.2009.02483.x.
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  - Lopes, Renato D., and Karen P. Alexander. “Antiplatelet therapy in older adults with non-ST-segment elevation acute coronary syndrome: considering risks and benefits..” The American Journal of Cardiology 104, no. 5 Suppl (September 2009): 16C-21C. https://doi.org/10.1016/j.amjcard.2009.06.021.
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  - Andrews, D., D. Williams, and K. Alexander. “Too much of a good thing - Air, that is - Reply.” Anaesthesia and Intensive Care 37, no. 4 (July 1, 2009): 664–65.
  - Melloni, Chiara, Karen P. Alexander, Fang-Shu Ou, Nancy M Allen LaPointe, Matthew T. Roe, L Kristin Newby, Khaula Baloch, P Michael Ho, John S. Rumsfeld, and Eric D. Peterson. “Predictors of early discontinuation of evidence-based medicine after acute coronary syndrome..” The American Journal of Cardiology 104, no. 2 (July 2009): 175–81. https://doi.org/10.1016/j.amjcard.2009.03.013.
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  - Afilalo, Jonathan, Sathya Karunananthan, Mark J. Eisenberg, Karen P. Alexander, and Howard Bergman. “Role of frailty in patients with cardiovascular disease..” The American Journal of Cardiology 103, no. 11 (June 2009): 1616–21. https://doi.org/10.1016/j.amjcard.2009.01.375.
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  - Armstrong, Paul W., and Karen P. Alexander. “Nebivolol in older adults with heart failure: reduced rates for seniors?.” Journal of the American College of Cardiology 53, no. 23 (June 2009): 2159–61. https://doi.org/10.1016/j.jacc.2009.03.019.
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  - Spinler, Sarah A., Fang-Shu Ou, Matthew T. Roe, W Brian Gibler, E Magnus Ohman, Charles V. Pollack, Karen P. Alexander, and Eric D. Peterson. “Weight-based dosing of enoxaparin in obese patients with non-ST-segment elevation acute coronary syndromes: results from the CRUSADE initiative..” Pharmacotherapy 29, no. 6 (June 2009): 631–38. https://doi.org/10.1592/phco.29.6.631.
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  - Lansky, Alexandra J., Roxana Mehran, Ecatarina Cristea, Helen Parise, Frederick Feit, E Magnus Ohman, Harvey D. White, et al. “Impact of gender and antithrombin strategy on early and late clinical outcomes in patients with non-ST-elevation acute coronary syndromes (from the ACUITY trial)..” The American Journal of Cardiology 103, no. 9 (May 2009): 1196–1203. https://doi.org/10.1016/j.amjcard.2009.01.030.
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  - Subherwal, Sumeet, Richard G. Bach, Anita Y. Chen, Brian F. Gage, Sunil V. Rao, L Kristin Newby, Tracy Y. Wang, et al. “Baseline risk of major bleeding in non-ST-segment-elevation myocardial infarction: the CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA Guidelines) Bleeding Score..” Circulation 119, no. 14 (April 14, 2009): 1873–82. https://doi.org/10.1161/CIRCULATIONAHA.108.828541.
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  - Melloni, C., E. D. Peterson, A. Y. Chen, L. A. Szczech, L. K. Newby, R. A. Harrington, W. B. Gibler, et al. “Cockcroft-Gault Versus Modification of Diet in Renal Disease: Importance of Glomerular Filtration Rate Formula for Classification of Chronic Kidney Disease in Patients With Non-ST-Segment Elevation Acute Coronary Syndromes Editorial Comment.” Journal of Urology 181, no. 4 (April 1, 2009): 1813–14.
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  - Alexander, Karen P., Anita Y. Chen, Matthew T. Roe, Tracy Y. Wang, Erik M. Ohman, David J. Magid, Michael P. Ho, Stephen D. Wiviott, Benjamin M. Scirica, and Eric D. Peterson. “Antithrombotic Strategy During Percutaneous Coronary Iintervention in NSTEMI: Update From ACTION Registry-GWTG.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A398–A398.
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  - Forman, Daniel E., Anita Y. Chen, Stephen D. Wiviott, Tracy Y. Wang, David J. Magid, and Karen P. Alexander. “ST-Elevation Myocardial Infarction Care and Outcomes for the Oldest-Old.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A325–A325.
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  - Gharacholou, Shahyar M., Anita Y. Chen, Karen P. Alexander, Jorge F. Saucedo, James de Lemos, Michael C. Kontos, Eric D. Peterson, John Rumsfeld, and Matthew T. Roe. “Limitations of Using Cardiac Catheterization Rates as a Quality Measure for Non ST-Segment Elevation Myocardial Infarction.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A370–A370.
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  - Kadakia, Mitul B., Nihar R. Desai, Karen P. Alexander, Anita Y. Chen, JoAnne M. Foody, Christopher P. Cannon, Stephen D. Wiviott, and Benjamin M. Scirica. “Utilization of Antithrombotic Agents Among Patients Admitted With Myocardial Infarction in the ACTION Registry-GWTG.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A324–25.
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  - Subherwal, Sumeet, Anita Y. Chen, Richard G. Bach, Matthew T. Roe, Eric D. Peterson, and Karen P. Alexander. “Risk of GUSTO Moderate or Severe Bleeding identified by the CRUSADE Bleeding Model.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A384–A384.
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  - Alexander, Karen P., Michael A. Blazing, Robert S. Rosenson, Elisabeth Hazard, Wilbert S. Aronow, Sidney C. Smith, and E Magnus Ohman. “Management of hyperlipidemia in older adults..” Journal of Cardiovascular Pharmacology and Therapeutics 14, no. 1 (March 2009): 49–58. https://doi.org/10.1177/1074248408328927.
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  - Lopes, Renato D., Karen P. Alexander, Steven V. Manoukian, Michel E. Bertrand, Frederick Feit, Harvey D. White, Charles V. Pollack, et al. “Advanced age, antithrombotic strategy, and bleeding in non-ST-segment elevation acute coronary syndromes: results from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial..” Journal of the American College of Cardiology 53, no. 12 (March 2009): 1021–30. https://doi.org/10.1016/j.jacc.2008.12.021.
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  - Arnold, Suzanne V., Karen P. Alexander, Frederick A. Masoudi, P Michael Ho, Lan Xiao, and John A. Spertus. “The effect of age on functional and mortality outcomes after acute myocardial infarction..” Journal of the American Geriatrics Society 57, no. 2 (February 2009): 209–17. https://doi.org/10.1111/j.1532-5415.2008.02106.x.
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  - Cohen, Marc, Karen P. Alexander, and Sunil V. Rao. “Bleeding after antithrombotic therapy in patients with acute ischemic heart disease: is it the drugs or how we use them?.” Journal of Thrombosis and Thrombolysis 26, no. 3 (December 2008): 175–82. https://doi.org/10.1007/s11239-007-0182-x.
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  - Wang, Tracy Y., Lan Xiao, Karen P. Alexander, Sunil V. Rao, Mikhail N. Kosiborod, John S. Rumsfeld, John A. Spertus, and Eric D. Peterson. “Antiplatelet therapy use after discharge among acute myocardial infarction patients with in-hospital bleeding..” Circulation 118, no. 21 (November 3, 2008): 2139–45. https://doi.org/10.1161/circulationaha.108.787143.
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  - Alexander, Karen P., Patricia A. Cowper, Judith A. Kempf, Barbara L. Lytle, and Eric D. Peterson. “Profile of chronic and recurrent angina pectoris in a referral population..” The American Journal of Cardiology 102, no. 10 (November 2008): 1301–6. https://doi.org/10.1016/j.amjcard.2008.07.006.
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  - Patel, Uptal D., Joshua Grab, Mikhail Kosiborod, Barbara Lytle, Eric D. Peterson, and Karen P. Alexander. “Impact of anemia on physical function and survival among patients with coronary artery disease..” Clinical Cardiology 31, no. 11 (November 2008): 546–50. https://doi.org/10.1002/clc.20283.
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  - Cavender, Matthew A., Karen P. Alexander, Samuel Broderick, Linda K. Shaw, Judith Kempf, and E Magnus Ohman. “Long-Term Morbidity and Mortality among Patients with Angina and Multivessel Coronary Artery Disease in the Duke Cardiovascular Databank.” Circulation 118, no. 18 (October 28, 2008): S853–S853.
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  - Fox, Caroline S., Paul Muntner, Anita Y. Chen, Karen P. Alexander, Matthew T. Roe, Jorge F. Saucedo, and Stephen D. Wiviott. “Short-Term Outcomes of STEMI and NSTEMI in Patients with Chronic Kidney Disease: A Report from the National Cardiovascular Data ACTION Registry.” Circulation 118, no. 18 (October 28, 2008): S966–S966.
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  - Reeves, Gordon R., Tracy Y. Wang, Kimberly J. Reid, Karen P. Alexander, Carole Decker, Homaa Ahmad, John A. Spertus, and Eric D. Peterson. “Dissociation between hospital performance of the smoking cessation counseling quality metric and cessation outcomes after myocardial infarction..” Arch Intern Med 168, no. 19 (October 27, 2008): 2111–17. https://doi.org/10.1001/archinte.168.19.2111.
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  - Roe, Matthew T., Fang-Shu Ou, Karen P. Alexander, Laura Kristin Newby, Joanne M. Foody, W Brian Gibler, William E. Boden, Erik Magnus Ohman, Sidney C. Smith, and Eric D. Peterson. “Patterns and prognostic implications of low high-density lipoprotein levels in patients with non-ST-segment elevation acute coronary syndromes..” European Heart Journal 29, no. 20 (October 2008): 2480–88. https://doi.org/10.1093/eurheartj/ehn364.
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  - Singh, Mandeep, Karen Alexander, Veronique L. Roger, Charanjit S. Rihal, Heather E. Whitson, Amir Lerman, Arschad Jahangir, and K Sreekumaran Nair. “Frailty and its potential relevance to cardiovascular care..” Mayo Clinic Proceedings 83, no. 10 (October 2008): 1146–53. https://doi.org/10.4065/83.10.1146.
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  - Wang, Tracy Y., Anita Y. Chen, Karen P. Alexander, E Magnus Ohman, W Brian Gibler, Eric D. Peterson, and Matthew T. Roe. “Excess heparin dosing among fibrinolytic-treated patients with ST-segment elevation myocardial infarction..” The American Journal of Medicine 121, no. 9 (September 2008): 805–10. https://doi.org/10.1016/j.amjmed.2008.04.023.
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  - Dunlay, Shannon M., Karen P. Alexander, Chiara Melloni, Jennifer L. Kraschnewski, Li Liang, W Brian Gibler, Matthew T. Roe, E Magnus Ohman, and Eric D. Peterson. “Medical records and quality of care in acute coronary syndromes: results from CRUSADE..” Archives of Internal Medicine 168, no. 15 (August 2008): 1692–98. https://doi.org/10.1001/archinte.168.15.1692.
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  - Lopes, Renato D., Karen P. Alexander, Gretchen Marcucci, Harvey D. White, Sarah Spinler, Jacques Col, Philip E. Aylward, Robert M. Califf, and Kenneth W. Mahaffey. “Outcomes in elderly patients with acute coronary syndromes randomized to enoxaparin vs. unfractionated heparin: results from the SYNERGY trial..” European Heart Journal 29, no. 15 (August 2008): 1827–33. https://doi.org/10.1093/eurheartj/ehn236.
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  - Melloni, Chiara, Karen P. Alexander, Anita Y. Chen, L Kristin Newby, Matthew T. Roe, Nancy M. Allen LaPointe, Charles V. Pollack, et al. “Unfractionated heparin dosing and risk of major bleeding in non-ST-segment elevation acute coronary syndromes..” American Heart Journal 156, no. 2 (August 2008): 209–15. https://doi.org/10.1016/j.ahj.2008.03.023.
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  - Alexander, Karen P., Anita Y. Chen, Tracy Y. Wang, Sunil V. Rao, L Kristin Newby, Nancy M Allen LaPointe, E Magnus Ohman, et al. “Transfusion practice and outcomes in non-ST-segment elevation acute coronary syndromes..” Am Heart J 155, no. 6 (June 2008): 1047–53. https://doi.org/10.1016/j.ahj.2008.01.009.
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  - Ho, P Michael, Marvin H. Eng, John S. Rumsfeld, John A. Spertus, Pamela N. Peterson, Philip G. Jones, Eric D. Peterson, et al. “The influence of age on health status outcomes after acute myocardial infarction..” American Heart Journal 155, no. 5 (May 2008): 855–61. https://doi.org/10.1016/j.ahj.2007.11.032.
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  - Melloni, Chiara, Eric D. Peterson, Anita Y. Chen, Lynda A. Szczech, L Kristin Newby, Robert A. Harrington, W Brian Gibler, et al. “Cockcroft-Gault versus modification of diet in renal disease: importance of glomerular filtration rate formula for classification of chronic kidney disease in patients with non-ST-segment elevation acute coronary syndromes..” Journal of the American College of Cardiology 51, no. 10 (March 2008): 991–96. https://doi.org/10.1016/j.jacc.2007.11.045.
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  - Melloni, Chiara, Karen P. Alexander, Sarah Milford-Beland, L Kristin Newby, Lynda A. Szczech, Charles V. Pollack, J Douglas Kirk, et al. “Prognostic value of troponins in patients with non-ST-segment elevation acute coronary syndromes and chronic kidney disease..” Clinical Cardiology 31, no. 3 (March 2008): 125–29. https://doi.org/10.1002/clc.20210.
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  - Dove, James T., Susan J. Zieman, Karen Alexander, and Andrew Miller. “President's page: Cardiovascular care in older adults: the ACC and SGC partnership builds new curriculum..” Journal of the American College of Cardiology 51, no. 6 (February 2008): 672–73. https://doi.org/10.1016/j.jacc.2008.01.002.
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  - Melloni, Chiara, Karen P. Alexander, Anita Y. Chen, Matthew T. Roe, L Kristin Newby, Magnus Ohman, W Brian Gibler, Sidney C. Smith, Charles V. Pollak, and Eric D. Peterson. “Unfractionated heparin dosing and major bleeding in non-ST-segment elevation acute coronary syndromes.” Circulation 116, no. 16 (October 16, 2007): 383–383.
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  - Wang, Tracy Y., Anita Y. Chen, Matthew T. Roe, Karen P. Alexander, L Kristin Newby, Sidney C. Smith, Sripal Bangalore, W Brian Gibler, E Magnus Ohman, and Eric D. Peterson. “Comparison of baseline characteristics, treatment patterns, and in-hospital outcomes of Asian versus non-Asian white Americans with non-ST-segment elevation acute coronary syndromes from the CRUSADE quality improvement initiative..” The American Journal of Cardiology 100, no. 3 (August 2007): 391–96. https://doi.org/10.1016/j.amjcard.2007.03.035.
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  - Wong, Cheuk-Kit, L Kristin Newby, Manju V. Bhapker, Phil E. Aylward, Matthias Pfisterer, Karen P. Alexander, Paul W. Armstrong, et al. “Use of evidence-based medicine for acute coronary syndromes in the elderly and very elderly: insights from the Sibrafiban vs aspirin to Yield Maximum Protection from ischemic Heart events postacute cOroNary sYndromes trials..” American Heart Journal 154, no. 2 (August 2007): 313–21. https://doi.org/10.1016/j.ahj.2007.04.031.
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  - LaPointe, Nancy M Allen, Anita Y. Chen, Karen P. Alexander, Matthew T. Roe, Charles V. Pollack, Barbara L. Lytle, Magnus E. Ohman, Brian W. Gibler, and Eric D. Peterson. “Enoxaparin dosing and associated risk of in-hospital bleeding and death in patients with non ST-segment elevation acute coronary syndromes..” Archives of Internal Medicine 167, no. 14 (July 2007): 1539–44. https://doi.org/10.1001/archinte.167.14.1539.
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  - Purser, J. L., G. G. Fillenbaum, and K. P. Alexander. “Response to Dr. Denkinger et al. [12].” Journal of the American Geriatrics Society 55, no. 6 (June 1, 2007): 968–69. https://doi.org/10.1111/j.1532-5415.2007.01193.x.
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  - Kraschnewski, Jennifer L., Li Liang, Shannon M. Dunlay, Chiara Melloni, Deborah B. Diercks, W Brian Gibler, Matthew T. Roe, E Magnus Ohman, Eric D. Peterson, and Karen P. Alexander. “Age, presentation, and emergency department diagnosis of acute coronary syndromes: Results from CRUSADE.” Circulation 115, no. 21 (May 29, 2007): E584–E584.
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  - Wang, Tracy Y., Lan Xiao, Karen P. Alexander, Mikhail N. Kosiborod, John S. Rumsfeld, John A. Spertus, and Eric D. Peterson. “Trends in antiplatelet therapy use following discharge among acute myocardial infarction patients with in-hospital bleeding.” Circulation 115, no. 21 (May 29, 2007): E575–E575.
  - Alexander, Karen P., L Kristin Newby, Christopher P. Cannon, Paul W. Armstrong, W Brian Gibler, Michael W. Rich, Frans Van de Werf, et al. “Acute coronary care in the elderly, part I: Non-ST-segment-elevation acute coronary syndromes: a scientific statement for healthcare professionals from the American Heart Association Council on Clinical Cardiology: in collaboration with the Society of Geriatric Cardiology..” Circulation 115, no. 19 (May 2007): 2549–69. https://doi.org/10.1161/circulationaha.107.182615.
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  - Alexander, Karen P., L Kristin Newby, Paul W. Armstrong, Christopher P. Cannon, W Brian Gibler, Michael W. Rich, Frans Van de Werf, et al. “Acute coronary care in the elderly, part II: ST-segment-elevation myocardial infarction: a scientific statement for healthcare professionals from the American Heart Association Council on Clinical Cardiology: in collaboration with the Society of Geriatric Cardiology..” Circulation 115, no. 19 (May 2007): 2570–89. https://doi.org/10.1161/circulationaha.107.182616.
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  - Skolnick, Adam H., Karen P. Alexander, Anita Y. Chen, Matthew T. Roe, Charles V. Pollack, E Magnus Ohman, John S. Rumsfeld, W Brian Gibler, Eric D. Peterson, and David J. Cohen. “Characteristics, management, and outcomes of 5,557 patients age > or =90 years with acute coronary syndromes: results from the CRUSADE Initiative..” J Am Coll Cardiol 49, no. 17 (May 1, 2007): 1790–97. https://doi.org/10.1016/j.jacc.2007.01.066.
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  - Frazier, Camille G., Karen P. Alexander, L Kristin Newby, Susan Anderson, Erik Iverson, Milton Packer, Jay Cohn, Sidney Goldstein, and Pamela S. Douglas. “Associations of gender and etiology with outcomes in heart failure with systolic dysfunction: a pooled analysis of 5 randomized control trials..” Journal of the American College of Cardiology 49, no. 13 (April 2007): 1450–58. https://doi.org/10.1016/j.jacc.2006.11.041.
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  - Ali, Robin, and Karen P. Alexander. “Statins for the primary prevention of cardiovascular events in older adults: a review of the evidence..” The American Journal of Geriatric Pharmacotherapy 5, no. 1 (March 2007): 52–63. https://doi.org/10.1016/j.amjopharm.2007.03.008.
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  - Purser, Jama L., Maragatha N. Kuchibhatla, Gerda G. Fillenbaum, Tina Harding, Eric D. Peterson, and Karen P. Alexander. “Identifying frailty in hospitalized older adults with significant coronary artery disease..” J Am Geriatr Soc 54, no. 11 (November 2006): 1674–81. https://doi.org/10.1111/j.1532-5415.2006.00914.x.
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  - Alexander, Karen P., Anita Y. Chen, L Kristin Newby, Nancy M Allen LaPointe, E Magnus Ohman, Matthew T. Roe, William E. Boden, and Eric D. Peterson. “Blood transfusion and mortality among patients with non-ST-segment elevation acute coronary syndromes: Results from CRUSADE.” Circulation 114, no. 18 (October 31, 2006): 701–701.
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  - Frazier, Camille G., Karen P. Alexander, L Kristin Newby, Milton Packer, Jay Cohn, Sidney Goldstein, Ake Hjalmarson, Susan Anderson, Erik Iverson, and Pamela S. Douglas. “Sex differences in heart failure with systolic dysfunction: A pooled analysis of five randomized control trials.” Circulation 114, no. 18 (October 31, 2006): 573–573.
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  - Mellori, Chiara, Eric D. Peterson, Anita Y. Chen, Lynda A. Szczech, L Kristin Newby, Robert A. Harrington, W Brian Gibler, et al. “Importance of glomerular filtration rate formula for determining chronic kidney disease and clinical care in patients with acute coronary syndromes.” Circulation 114, no. 18 (October 31, 2006): 406–406.
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  - Alexander, Karen P., Anita Y. Chen, L Kristin Newby, Janice B. Schwartz, Rita F. Redberg, Judith S. Hochman, Matthew T. Roe, et al. “Sex differences in major bleeding with glycoprotein IIb/IIIa inhibitors: results from the CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA guidelines) initiative..” Circulation 114, no. 13 (September 18, 2006): 1380–87. https://doi.org/10.1161/circulationaha.106.620815.
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  - Kraschnewski, J. L., K. P. Alexander, and E. D. Peterson. “Coronary artery disease in later life.” Generations 30, no. 3 (September 1, 2006): 17–23.
  - Alexander, Karen P., Laura Kristin Newby, Manju V. Bhapkar, Harvey D. White, Judith S. Hochman, Matthias E. Pfisterer, David J. Moliterno, et al. “International variation in invasive care of the elderly with acute coronary syndromes..” European Heart Journal 27, no. 13 (July 2006): 1558–64. https://doi.org/10.1093/eurheartj/ehl067.
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  - Swaminathan, Rajesh V., and Karen P. Alexander. “Pulse pressure and vascular risk in the elderly: associations and clinical implications..” The American Journal of Geriatric Cardiology 15, no. 4 (July 2006): 226–32. https://doi.org/10.1111/j.1076-7460.2006.04774.x.
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  - Gharacholou, S Michael, and Karen P. Alexander. “Issues with care in the elderly patient presenting with acute ischemia..” Current Heart Failure Reports 3, no. 2 (June 2006): 51–56. https://doi.org/10.1007/s11897-006-0002-1.
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  - Alexander, K. P., and E. D. Peterson. “In reply [6].” Journal of the American Medical Association 295, no. 16 (April 26, 2006). https://doi.org/10.1001/jama.295.16.1897-b.
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  - Alexander, Karen P., and Eric D. Peterson. “Treatment of non-ST-elevation acute coronary syndrome in the elderly: current practice and future opportunities..” The American Journal of Geriatric Cardiology 15, no. 1 (January 2006): 42–49. https://doi.org/10.1111/j.1076-7460.2006.04642.x.
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  - Kulkarni, Sonali P., Karen P. Alexander, Barbara Lytle, Gerardo Heiss, and Eric D. Peterson. “Long-term adherence with cardiovascular drug regimens..” Am Heart J 151, no. 1 (January 2006): 185–91. https://doi.org/10.1016/j.ahj.2005.02.038.
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  - Alexander, Karen P., Anita Y. Chen, Matthew T. Roe, L Kristin Newby, C Michael Gibson, Nancy M. Allen-LaPointe, Charles Pollack, et al. “Excess dosing of antiplatelet and antithrombin agents in the treatment of non-ST-segment elevation acute coronary syndromes..” Jama 294, no. 24 (December 2005): 3108–16. https://doi.org/10.1001/jama.294.24.3108.
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  - Alexander, Karen P., Matthew T. Roe, Anita Y. Chen, Barbara L. Lytle, Charles V. Pollack, Joanne M. Foody, William E. Boden, et al. “Evolution in cardiovascular care for elderly patients with non-ST-segment elevation acute coronary syndromes: results from the CRUSADE National Quality Improvement Initiative..” Journal of the American College of Cardiology 46, no. 8 (October 2005): 1479–87. https://doi.org/10.1016/j.jacc.2005.05.084.
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  - Yang, Xin, Karen P. Alexander, Anita Y. Chen, Matthew T. Roe, Ralph G. Brindis, Sunil V. Rao, W Brian Gibler, E Magnus Ohman, Eric D. Peterson, and Eric D. CRUSADE Investigators. “The implications of blood transfusions for patients with non-ST-segment elevation acute coronary syndromes: results from the CRUSADE National Quality Improvement Initiative..” Journal of the American College of Cardiology 46, no. 8 (October 2005): 1490–95. https://doi.org/10.1016/j.jacc.2005.06.072.
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  - Gharacholou, S Michael, and Karen P. Alexander. “Issues with care in the elderly patient presenting with acute ischemia..” Current Cardiology Reports 7, no. 4 (July 2005): 270–75. https://doi.org/10.1007/s11886-005-0048-9.
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  - DeLong, E. R., B. L. Lytle, P. A. Cowper, K. P. Alexander, E. D. Peterson, and D. B. Mark. “Research, managed care, and patient privacy: Challenges to successful collaboration.” Journal of Clinical Outcomes Management 12, no. 3 (March 1, 2005): 151–56.
  - Mehta, Rajendra H., Christopher B. Granger, Karen P. Alexander, Eduardo Bossone, Harvey D. White, and Michael H. Sketch. “Reperfusion strategies for acute myocardial infarction in the elderly: benefits and risks..” Journal of the American College of Cardiology 45, no. 4 (February 2005): 471–78. https://doi.org/10.1016/j.jacc.2004.10.065.
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  - Heitner, John F., Igor Klem, Karen Alexander, Louise Thomson, Trip J. Meine, Manesh R. Patel, Salman A. Haq, Dipan J. Shah, and Raymond J. Kim. “The case of the disappearing myxoma..” Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance 7, no. 5 (January 2005): 841–43. https://doi.org/10.1080/10976640500288156.
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  - Mehta, S. R., S. Yusuf, R. Díaz, J. Zhu, P. Pais, D. Xavier, E. Paolasso, et al. “Effect of glucose-insulin-potassium infusion on mortality in patients with acute ST-segment elevation myocardial infarction: The CREATE-ECLA randomized controlled trial.” Journal of the American Medical Association 293, no. 4 (2005): 437–46. https://doi.org/10.1001/jama.293.4.437.
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  - Parsons, Elizabeth, L Kristin Newby, Manjushri V. Bhapkar, Karen P. Alexander, Harvey D. White, Svati H. Shah, Cheryl D. Bushnell, Robert M. Califf, and Robert M. Symphony and 2nd Symphony Investigators. “Postmenopausal hormone use in women with acute coronary syndromes..” Journal of Women’S Health (2002) 13, no. 8 (October 2004): 863–71. https://doi.org/10.1089/jwh.2004.13.863.
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  - Peterson, Eric D., Karen P. Alexander, David J. Malenka, Edward L. Hannan, Gerald T. O’Conner, Ben D. McCallister, William S. Weintraub, Fred L. Grover, and Fred L. American Heart Association Chronic CAD Working Group. “Multicenter experience in revascularization of very elderly patients..” American Heart Journal 148, no. 3 (September 2004): 486–92. https://doi.org/10.1016/j.ahj.2004.03.039.
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  - Alexander, Karen P., and Mimi S. Biswas. “Heart failure and the elderly: disease diversity, data, and delivery of care..” American Heart Journal 146, no. 2 (August 2003): 194–96. https://doi.org/10.1016/s0002-8703(03)00190-x.
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  - Jones, D. L., M. Ishii, A. LaPerriere, H. Stanley, M. Antoni, G. Ironson, N. Schneiderman, et al. “Influencing medication adherence among women with AIDS..” Aids Care 15, no. 4 (August 2003): 463–74. https://doi.org/10.1080/0954012031000134700.
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  - Alexander, Karen P., and Eric D. Peterson. “Evidence-based care for all patients..” The American Journal of Medicine 114, no. 4 (March 2003): 333–35. https://doi.org/10.1016/s0002-9343(03)00069-x.
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  - Pasquali, Sara K., Karen P. Alexander, Laura P. Coombs, Barbara L. Lytle, and Eric D. Peterson. “Effect of cardiac rehabilitation on functional outcomes after coronary revascularization..” American Heart Journal 145, no. 3 (March 2003): 445–51. https://doi.org/10.1067/mhj.2003.172.
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  - Shah, S. H., K. P. Alexander, and E. D. Peterson. “PCI in women.” Cardiology Review 20, no. 3 (March 1, 2003): 24–29.
  - Frazier, Camille, and Karen Alexander. “The finer points of race and hypertension..” American Heart Journal 145, no. 2 (February 2003): 206–8. https://doi.org/10.1067/mhj.2003.108.
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  - Shah, Svati H., and Karen P. Alexander. “Hormone Replacement Therapy for Primary and Secondary Prevention of Heart Disease..” Current Treatment Options in Cardiovascular Medicine 5, no. 1 (February 2003): 25–33. https://doi.org/10.1007/s11936-003-0012-1.
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  - Califf, Robert M., and Karen P. Alexander. “Cardiovascular research in the elderly: challenges, opportunities, and impact..” Postgraduate Medicine 112, no. 6 Suppl Heart (December 2002): 6–11. https://doi.org/10.3810/pgm.12.2002.suppl24.125.
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  - Alexander, K. P., M. V. Bhapkar, H. D. White, J. S. Hochman, M. E. Pfisterer, D. J. Moliterno, R. M. Califf, et al. “Paradoxical use of angiography with advancing age: Insights from an international trial population.” Journal of the American College of Cardiology 39, no. 5 (March 6, 2002): 152A-152A.
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  - Alexander, K. P., T. Harding, L. P. Coombs, K. Taylor, and E. D. Peterson. “Aging and patient preferences regarding invasive cardiac care.” Journal of the American College of Cardiology 39, no. 5 (March 6, 2002): 197A-197A.
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  - Pasquali, S. K., K. P. Alexander, L. P. Coombs, B. L. Lytle, and E. D. Peterson. “Effect of cardiac rehabilitation on functional outcomes following coronary revascularization.” Journal of the American College of Cardiology 39, no. 5 (March 6, 2002): 151A-151A.
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  - Pasquali, S. K., K. P. Alexander, B. L. Lytle, L. P. Coombs, and E. D. Peterson. “Testing an intervention to increase cardiac rehabilitation enrollment after coronary artery bypass grafting..” The American Journal of Cardiology 88, no. 12 (December 2001): 1415-A6. https://doi.org/10.1016/s0002-9149(01)02123-3.
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  - Pasquali, S. K., K. P. Alexander, and E. D. Peterson. “Cardiac rehabilitation in the elderly..” American Heart Journal 142, no. 5 (November 2001): 748–55. https://doi.org/10.1067/mhj.2001.119134.
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  - Alexander, K. P., and E. D. Peterson. “Medical and surgical management of coronary artery disease in women..” The American Journal of Managed Care 7, no. 10 (October 2001): 951–56.
  - Lee, P. Y., K. P. Alexander, B. G. Hammill, S. K. Pasquali, and E. D. Peterson. “Representation of elderly persons and women in published randomized trials of acute coronary syndromes..” Jama 286, no. 6 (August 2001): 708–13. https://doi.org/10.1001/jama.286.6.708.
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  - Alexander, K. P., A. N. Galanos, J. G. Jollis, J. A. Stafford, and E. D. Peterson. “Post-myocardial infarction risk stratification in elderly patients..” American Heart Journal 142, no. 1 (July 2001): 37–42. https://doi.org/10.1067/mhj.2001.115589.
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  - Alexander, K. P., L. K. Newby, A. S. Hellkamp, R. A. Harrington, E. D. Peterson, S. Kopecky, A. Langer, et al. “Initiation of hormone replacement therapy after acute myocardial infarction is associated with more cardiac events during follow-up..” Journal of the American College of Cardiology 38, no. 1 (July 2001): 1–7. https://doi.org/10.1016/s0735-1097(01)01329-8.
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  - Alexander, J. H., K. P. Alexander, P. J. Joski, M. S. Cuffe, and R. H. Peter. “Morbidly obese patients undergoing cardiac catheterization: Less disease, less aggressive revascularization, and similar outcomes.” Journal of the American College of Cardiology 37, no. 2 (February 1, 2001): 367A-368A.
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  - Lee, P. Y., K. P. Alexander, B. G. Hammill, S. K. Pasquali, and E. D. Peterson. “Representation of the elderly in cardiovascular clinical trials.” Journal of the American College of Cardiology 37, no. 2 (February 1, 2001): 497A-497A.
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  - Alexander, K. P., D. J. Malenka, E. L. Hannan, B. D. McCallister, and E. D. Peterson. “Outcomes of PCI in the aged: Results from 6 large registries.” Circulation 102, no. 18 (October 31, 2000): 642–642.
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  - Alexander, K. P., L. L. Barbara, L. L. Choi, M. B. Daniel, and P. D. Eric. “Women have worse functional outcomes following bypass surgery.” Circulation 102, no. 18 (October 31, 2000): 839–839.
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  - Bahit, M. C., C. B. Granger, K. P. Alexander, J. Kramer, N. M. A. Lapointe, and R. M. Califf. “Applying the evidence: Opportunity in US for 80,000 additional lives saved per year..” Circulation 102, no. 18 (October 31, 2000): 873–873.
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  - Peterson, E. D., K. P. Alexander, G. T. O’Connor, F. L. Grover, E. L. Hannan, B. D. McCallister, and W. S. Weintraub. “The safety of coronary artery bypass surgery in the aged.” Circulation 102, no. 18 (October 31, 2000): 680-+.
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  - Alexander, K. P., K. J. Anstrom, L. H. Muhlbaier, R. D. Grosswald, P. K. Smith, R. H. Jones, and E. D. Peterson. “Outcomes of cardiac surgery in patients > or = 80 years: results from the National Cardiovascular Network..” Journal of the American College of Cardiology 35, no. 3 (March 2000): 731–38. https://doi.org/10.1016/s0735-1097(99)00606-3.
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  - Alexander, K., L. J. Shaw, L. K. Shaw, E. DeLong, D. Mark, and E. Peterson. “Erratum: Value of exercise treadmill testing in women. Low dose dobutamine echocardiography predicts improvement in functional capacity after exercise training in patients with ischemic cardiomyopathy (Journal of the American College of Cardiology (1998) 32 (1657-1664)).” Journal of the American College of Cardiology 33, no. 1 (February 10, 1999). https://doi.org/10.1016/S0735-1097(98)00655-X.
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  - Alexander, K. P., E. D. Peterson, C. B. Granger, A. C. Casas, F. Van De Werf, P. W. Armstrong, A. Guerci, E. J. Topol, and R. M. Califf. “Potential impact of evidence-based medicine in acute coronary syndromes: Insights from GUSTO-IIb.” Journal of the American College of Cardiology 32, no. 7 (December 1, 1998): 2023–30. https://doi.org/10.1016/S0735-1097(98)00466-5.
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  - Alexander, K. P., E. D. Peterson, C. B. Granger, A. C. Casas, F. Van de Werf, P. W. Armstrong, A. Guerci, E. J. Topol, and R. M. Califf. “Potential impact of evidence-based medicine in acute coronary syndromes: insights from GUSTO-IIb. Global Use of Strategies to Open Occluded Arteries in Acute Coronary Syndromes trial..” Journal of the American College of Cardiology 32, no. 7 (December 1998): 2023–30. https://doi.org/10.1016/s0735-1097(98)00466-5.
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  - Alexander, K. P., L. J. Shaw, L. K. Shaw, E. R. Delong, D. B. Mark, and E. D. Peterson. “Value of exercise treadmill testing in women..” Journal of the American College of Cardiology 32, no. 6 (November 1998): 1657–64. https://doi.org/10.1016/s0735-1097(98)00451-3.
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  - Peterson, E. D., and K. P. Alexander. “Learning to suspect the unexpected: evaluating women with cardiac syndromes..” American Heart Journal 136, no. 2 (August 1998): 186–88. https://doi.org/10.1053/hj.1998.v136.89736.
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  - Alexander, J. H., K. Alexander, D. F. Kong, C. Y. Tung, and D. Whellan. “Session highlights from the American Heart Association Scientific Sessions: November 9-12, 1997..” American Heart Journal 135, no. 1 (January 1998): 157–80. https://doi.org/10.1016/s0002-8703(98)70357-6.
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  - Alexander, K. P., and E. D. Peterson. “Coronary artery bypass grafting in the elderly..” American Heart Journal 134, no. 5 Pt 1 (November 1997): 856–64. https://doi.org/10.1016/s0002-8703(97)80008-7.
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  - Alexander, K. P., and E. D. Peterson. “Coronary artery bypass grafting in the elderly.” American Heart Journal 134, no. 5 (November 1997): 856–64. https://doi.org/10.1016/S0002-8703(97)80008-7.
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  - Alexander, K. P., E. D. Peterson, L. H. Muhlbaier, R. D. Grosswald, and M. J. Lanzilotta. “Cardiac surgery outcomes in 3,220 octogenarians: Results from the National Cardiovascular Network.” Circulation 96, no. 8 (October 21, 1997): 59–59.
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  - Alexander, K. P., E. D. Peterson, N. E. ClappChanning, L. C. Lam, R. B. Williams, and D. B. Mark. “Functional outcome of CABG in the elderly.” Circulation 96, no. 8 (October 21, 1997): 2066–2066.
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  - Alexander, K. P., E. D. Peterson, A. S. Hellkamp, C. B. Granger, E. J. Topol, and R. M. Califf. “Early catheterization is standard strategy in unstable angina/NQWMI: Results from GUSTO IIb.” Journal of the American College of Cardiology 29, no. 2 (February 1, 1997): 5614–5614.
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  - Alexander, K. P., E. D. Peterson, K. W. Mahaffey, A. C. Casas, C. B. Granger, F. VandeWerf, P. W. Armstrong, D. B. Mark, E. J. Topol, and R. M. Califf. “Medical interventions in unstable angina: Does international clinical practice match evidence-based guidelines?.” Journal of the American College of Cardiology 29, no. 2 (February 1, 1997): 23138–23138.
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  - Alexander, K. P., and D. B. Mark. “Effect of gender on angioplasty outcome: are we closer to the answer?.” Mayo Clinic Proceedings 72, no. 1 (January 1997): 89–91. https://doi.org/10.1016/s0025-6196(11)64736-8.
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  - Alexander, K. P., and E. D. Peterson. “Coronary artery bypass grafting in the elderly.” American Heart Journal 134, no. 5 I (January 1, 1997): 856–64. https://doi.org/10.1016/S0002-8703(97)80008-7.
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- Conference Papers
  - Alexander, Karen P., Kristi Prather, Kevin J. Anstrom, Daniel Mark, Ori Ben-Yehuda, Linda Davidson-Ray, Giora Weisz, Ramin Farzaneh-Far, Gregg Stone, and E Magnus Ohman. “Angina and Quality of Life Following PCI With Incomplete Revascularization: Results From the Ranolazine for Incomplete Vessel Revascularization (RIVER-PCI) Trial.” In Circulation, 132:2273–2273. LIPPINCOTT WILLIAMS & WILKINS, 2015.
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  - Zimerman, Andre, Amanda L. Stebbins, Renato D. Lopes, Patricia O. Guimaraes, Stefan K. James, John H. Alexander, Pierluigi Tricoci, et al. “Adverse Event Reporting in > 48,000 Participants in Four Acute Coronary Syndrome Trials.” In Circulation, Vol. 132. LIPPINCOTT WILLIAMS & WILKINS, 2015.
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  - Dodson, J. A., Y. Wang, S. I. Chaudhry, K. P. Alexander, F. A. Masoudi, J. A. Spertus, B. Nallamothu, et al. “National trends in rehospitalization for bleeding after acute myocardial infarction in the oldest old.” In Journal of the American Geriatrics Society, 62:S41–S41. WILEY-BLACKWELL, 2014.
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  - Bagai, Akshay, Yongfei Wang, Tracy Y. Wang, Jeptha Curtis, Hitinder S. Gurm, Eric D. Peterson, Jorge F. Saucedo, et al. “In-Hospital ADP Receptor Inhibitor Switching in Myocardial Infarction Patients Treated With Percutaneous Coronary Intervention: Insights From the National Cardiovascular Data Registry (R).” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Dodson, John A., Yun Wang, Karen P. Alexander, Fred Masoudi, John A. Spertus, Sarwat I. Chaudhry, Iersey Chen, et al. “National Trends in Rehospitalization for Bleeding After Acute Myocardial Infarction in Older Patients, 1999-2010.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Shen, Lan, Shuang Li, Laine Thomas, Tracy Y. Wang, Karen P. Alexander, Bimal Shah, Eric Peterson, and Matthew T. Roe. “The Association of Transfer-out Rates from Hospitals Without Revascularization Capabilities and Long-term Mortality Risk Among Older Nstemi Patients.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Dodson, John A., Kimberly J. Reid, Thomas M. Gill, Harlan M. Krumholz, Daniel E. Forman, John A. Spertus, Michael W. Rich, Suzanne V. Arnold, and Karen P. Alexander. “SLOW GAIT AMONG OLDER ADULTS POST-AMI AND RISK FOR HOSPITAL READMISSION.” In Journal of the American College of Cardiology, 59:E1914–E1914. Elsevier BV, 2012. https://doi.org/10.1016/s0735-1097(12)61915-9.
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  - Chin, Chee Tang, Tracy Y. Wang, Anita Y. Chen, Robin Mathews, Karen P. Alexander, Matthew T. Roe, and Eric D. Peterson. “COMPARISON OF TRENDS IN IN-HOSPITAL AND LONG-TERM OUTCOMES OVER TIME AMONG OLDER PATIENTS WITH NON-ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION: INSIGHTS FROM THE CRUSADE QUALITY IMPROVEMENT REGISTRY.” In Journal of the American College of Cardiology, 57:E905–E905. Elsevier BV, 2011. https://doi.org/10.1016/s0735-1097(11)60905-4.
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  - Desai, Nihar, Anita Y. Chen, Stephen D. Wiviott, Marc S. Sabatine, Karen P. Alexander, Matthew T. Roe, Eric D. Peterson, and Bimal R. Shah. “CHALLENGES IN THE TREATMENT OF NSTEMI PATIENTS AT HIGH RISK FOR BOTH ISCHEMIC AND BLEEDING EVENTS: INSIGHTS FROM THE ACTION REGISTRY-GWTG.” In Journal of the American College of Cardiology, 57:E913–E913. Elsevier BV, 2011. https://doi.org/10.1016/s0735-1097(11)60913-3.
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  - Fosbøl, Emil L., Tracy Y. Wang, Jonathan Piccini, Renato D. Lopes, Bimal Shah, Karen P. Alexander, Shuang Li, Matthew T. Roe, and Eric D. Peterson. “LONG-TERM SAFETY OF ANTITHROMBOTIC THERAPY IN NON-ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION PATIENTS WITH ATRIAL FIBRILLATION.” In Journal of the American College of Cardiology, 57:E948–E948. Elsevier BV, 2011. https://doi.org/10.1016/s0735-1097(11)60948-0.
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  - Martin, Seth S., Kensey Gosch, Krishnaji Kulkarni, John A. Spertus, Robin Mathews, L Kristin Newby, Karen P. Alexander, and Tracy Y. Wang. “PATIENT AND PROVIDER FACTORS IN LIPID GOAL ATTAINMENT AFTER ACUTE MYOCARDIAL INFARCTION: INSIGHTS FROM THE TRANSLATIONAL RESEARCH INVESTIGATING UNDERLYING DISPARITIES IN ACUTE MYOCARDIAL INFARCTION PATIENTS' HEALTH STATUS (TRIUMPH) STUDY.” In Journal of the American College of Cardiology, 57:E573–E573. Elsevier BV, 2011. https://doi.org/10.1016/s0735-1097(11)60573-1.
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  - Subherwal, Sumeet, Shuang Li, Manesh R. Patel, Deepak L. Bhatt, Tracy Y. Wang, Karen P. Alexander, E Magnus Ohman, W Brian Gibler, Eric D. Peterson, and Matthew T. Roe. “IMPACT OF POLYVASCULAR DISEASE ON LONG-TERM MORTALITY IN OLDER PATIENTS WITH NON-ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION.” In Journal of the American College of Cardiology, 57:E992–E992. Elsevier BV, 2011. https://doi.org/10.1016/s0735-1097(11)60992-3.
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  - Afilalo, Jonathan, Mark J. Eisenberg, Jean-Francois Morin, Howard Bergman, Johanne Monette, Nicolas Noiseux, Louis P. Perrault, et al. “Gait Speed as a Predictor of Mortality and Major Morbidity in Older Adults Undergoing Cardiac Surgery: Preliminary Results From the FRAILTY ABC'S Study.” In Circulation, 120:S988–89. LIPPINCOTT WILLIAMS & WILKINS, 2009.
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  - Shah, Bimal R., Matthew T. Roe, Anita Y. Chen, Karen P. Alexander, Tracy Y. Wang, E Magnus Ohman, W Brian Gibler, and Eric D. Peterson. “Association Between Hospital Process Performance and 1-Year Post-discharge Mortality in Patients With Non-ST-elevation Myocardial Infarction: Results From 36,262 Patients.” In Circulation, 120:S1086–S1086. LIPPINCOTT WILLIAMS & WILKINS, 2009.
  - Tsai, Thomas T., Thomas M. Maddox, Matthew T. Roe, David Dai, Karen P. Alexander, P Michael Ho, John C. Messenger, Brahmajee K. Nallamothu, Eric D. Peterson, and John S. Rumsfeld. “Use of Contraindicated Anti-Thrombotics in Dialysis Patients Undergoing Percutaneous Coronary Interventions: Insights From the NCDR Cath-PCI Registry.” In Circulation, 120:S414–S414. LIPPINCOTT WILLIAMS & WILKINS, 2009.
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  - Wang, Tracy Y., Anita Y. Chen, Bimal R. Shah, Matthew T. Roe, Karen P. Alexander, E Magnus Ohman, W Brian Gibler, and Eric D. Peterson. “Readmission Rates Among Patients With Non-ST-Segment Elevation Myocardial Infarction: Results in 38,131 Patients From the CRUSADE Quality Improvement Initiative.” In Circulation, 120:S436–37. LIPPINCOTT WILLIAMS & WILKINS, 2009.
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  - Alexander, Karen P., Chiara Melloni, A. Pappas, L Kristin Newby, Nancy M Allen LaPointe, E Magnus Ohman, W Brian Gibler, Matthew T. Roe, and Eric D. Peterson. “Potency of statins track with intensity of overall secondary prevention.” In Circulation, 117:E453–E453. LIPPINCOTT WILLIAMS & WILKINS, 2008.
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  - Melloni, Chiara, Karen P. Alexander, Fang-Shu Ou, Nancy M Allen LaPointe, Matthew T. Roe, and Eric D. Peterson. “Factors associated with patient reported self-discontinuation of prescribed medicine after non-ST-segment elevation acute coronary syndromes.” In Circulation, 117:E418–E418. LIPPINCOTT WILLIAMS & WILKINS, 2008.
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  - Alexander, Karen P., Richard G. Bach, Anita Y. Chen, Sumeet Subherwal, Brian F. Gage, Sunil V. Rao, W Brian Gibler, et al. “Bleeding and ischemic events run parallel in NSTEMI patients.” In Journal of the American College of Cardiology, 51:A207–8. ELSEVIER SCIENCE INC, 2008.
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  - Subherwal, Sumeet, Richard G. Bach, Anita Y. Chen, Brian F. Gage, Sunil V. Rao, Tracy Y. Wang, W Brian Gibler, et al. “The CRUSADE bleeding score to assess baseline risk of major bleeding in non-ST-segment elevation myocardial infarction.” In Journal of the American College of Cardiology, 51:A212–A212. ELSEVIER SCIENCE INC, 2008.
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  - Wang, Tracy Y., Anita Y. Chen, Eric D. Peterson, Karen P. Alexander, E Magnus Ohman, W Brian Gibler, and Matthew T. Roe. “Incidence and bleeding outcomes of excess unfractionated heparin dosing among patients with ST-Segment elevation myocardial infarction undergoing fibrinolysis.” In Journal of the American College of Cardiology, 51:A203–A203. ELSEVIER SCIENCE INC, 2008.
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  - Alexander, Karen P., Anita Y. Chen, Matthew T. Roe, L Kristin Newby, Brian Gibler, E Magnus Ohman, Charles V. Pollack, and Eric D. Peterson. “Decline in GP 2b3a inhibitor overdosing with site-specific feedback in CRUSADE.” In Circulation, 116:798–99. LIPPINCOTT WILLIAMS & WILKINS, 2007.
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  - Wang, Tracy Y., Anita Y. Chen, Magnus Ohman, Karen P. Alexander, Charles V. Pollack, Sidney C. Smith, W Brian Gibler, Matthew T. Roe, and Eric D. Peterson. “Contemporary patterns of reperfusion for elderly patients with ST-segment elevation myocardial infarction.” In Circulation, 115:E582–E582. LIPPINCOTT WILLIAMS & WILKINS, 2007.
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  - Alexander, Karen P., Patricia A. Cowper, Barbara L. Lylte, Judith A. Kempf, and Eric D. Peterson. “Predictors of persistent angina among coronary disease patients.” In Journal of the American College of Cardiology, 49:232A-232A. ELSEVIER SCIENCE INC, 2007.
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  - Alexander, Karen P., Patricia A. Cowper, Barbara L. Lytle, Judith A. Kempf, and Eric D. Peterson. “Less is better, none is best: Angina and health related quality of life.” In Journal of the American College of Cardiology, 49:229A-229A. ELSEVIER SCIENCE INC, 2007.
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  - Roe, Matthew T., Karen P. Alexander, Fang-Shou Ou, L Kristin Newby, W Brian Gibler, Charles V. Pollack, E Magnus Ohman, Sidney C. Smith, and Eric D. Peterson. “Patterns of HDL levels in patients with non-ST-segment elevation acute coronary syndromes and association with clinical outcomes.” In Journal of the American College of Cardiology, 49:366A-366A. ELSEVIER SCIENCE INC, 2007.
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  - Wang, Tracy Y., Anita Y. Chen, Matthew T. Roe, Karen P. Alexander, L Kristin Newby, Sidney C. Smith, Sripal Bangalore, W Brian Gibler, E Magnus Ohman, and Eric D. Peterson. “Increased bleeding risk among Asians with non-ST-segment elevation acute coronary syndromes: Insights from the CRUSADE quality improvement initiative.” In Journal of the American College of Cardiology, 49:208A-208A. ELSEVIER SCIENCE INC, 2007.
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  - Alexander, Karen P., E Magnus Ohman, Michel E. Bertrand, Frederic Feit, Charles V. Pollack, James Hoekstra, Bernard J. Gersh, Harvey D. White, and Gregg W. Stone. “Outcomes in elderly patients undergoing PCI treated with bivalirudin monotherapy versus glycoprotein IIb/IIIa inhibitors with hepaiin or LMWH: Results from the randomized ACUITY trial.” In American Journal of Cardiology, 98:18M-18M. EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC, 2006.
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  - Mehta, R. H., E. D. Peterson, L. Liang, K. P. Alexander, W. B. Gibler, E. M. Ohman, C. V. Pollack, and M. T. Roe. “Contraindications to cardiac catheterization in non-ST-elevation acute coronary syndromes: Insights from the CRUSADE national quality improvement initiative.” In European Heart Journal, 27:183–183. OXFORD UNIV PRESS, 2006.
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  - Alexander, Karen P., Jyotsna Mulgund, Barbara Lytle, and Eric Peterson. “Long-term implications of discharge anemia in a cardiovascular population.” In Circulation, 113:E795–E795. LIPPINCOTT WILLIAMS & WILKINS, 2006.
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  - Dunlay, Shannon M., Li Liang, Chiara Melloni, Jennifer L. Kraschnewski, Karen P. Alexander, W Brian Gibler, Matthew T. Roe, E Magnus Ohman, and Eric D. Peterson. “Quality of medical record documentation in an acute coronary syndrome population: Results from CRUSADE.” In Circulation, 113:E802–3. LIPPINCOTT WILLIAMS & WILKINS, 2006.
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  - LaPointe, N. M. A., K. P. Alexander, A. Y. Chen, M. T. Roe, C. V. Pollack, E. M. Ohman, W. B. Gibler, and E. D. Peterson. “Enoxaparin dosing and bleeding in real world practice: Results from CRUSADE.” In Journal of the American College of Cardiology, 47:235A-235A. ELSEVIER SCIENCE INC, 2006.
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  - Peterson, E. D., A. Y. Chen, K. P. Alexander, N. M. A. LaPointe, E. S. Fraulo, L. K. Newby, M. T. Roe, W. B. Gibler, and E. M. Ohman. “The association between hospital guideline adherence, dosing safety, and patient outcomes: Results from the CRUSADE quality improvement initiative.” In Journal of the American College of Cardiology, 47:255A-255A. ELSEVIER SCIENCE INC, 2006.
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  - Alexander, K. P., A. Y. Chen, M. T. Roe, L. K. Newby, C. M. Gibson, J. Schwartz, J. S. Hochman, et al. “Sex differences in glycoprotein 11b/111a inhibitor dosing and bleeding in acute coronary syndromes: Results from CRUSADE.” In Circulation, 112:U491–92. LIPPINCOTT WILLIAMS & WILKINS, 2005.
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  - Melloni, C., M. T. Roe, S. Milford-Boland, K. P. Alexander, L. K. Newby, L. A. Szczech, C. V. Pollack, et al. “Renal insufficiency, troponin, and risk of death among patients with non-ST-segment elevation acute coronary syndromes.” In Circulation, 112:U587–88. LIPPINCOTT WILLIAMS & WILKINS, 2005.
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  - Spinler, S., K. P. Alexander, A. Y. Chen, M. T. Roe, W. B. Gibler, M. Ohman, and E. D. Peterson. “Predictors of excess dosing of injectable antithrombotics in patients with non-ST-segment elevation acute coronary syndromes..” In Pharmacotherapy, 25:1437–38. PHARMACOTHERAPY PUBLICATIONS INC, 2005.
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  - Alexander, K. P., A. Y. Chen, M. T Roe, L. K. Newby, W. B. Gibler, E. M. Ohman, and E. D. Peterson. “Antiplatelet and antithrombin dose variation in patients with non-ST-segment elevation acute coronary syndromes.” In Circulation, 111:E312–13. LIPPINCOTT WILLIAMS & WILKINS, 2005.
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  - Alexander, K. P., J. L. Sun, T. Harding, and B. Lee. “Who is right and what matters? Frailty in patients with cardiovascular disease.” In Circulation, 111:E339–40. LIPPINCOTT WILLIAMS & WILKINS, 2005.
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  - Lytle, Barbara L., Gregory J. Shook, Karen P. Alexander, Patricia A. Cowper, Daniel B. Mark, and Elizabeth R. DeLong. “1153-74 Physician counseling can influence health-related quality of life.” In Journal of the American College of Cardiology, 43:A418–A418. Elsevier BV, 2004. https://doi.org/10.1016/s0735-1097(04)91763-9.
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  - Alexander, K. P., B. Lytle, Y. Li, and E. Peterson. “Elderly patients have better functioning, less angina at one year with coronary artery bypass graft.” In Journal of the American College of Cardiology, 41:220A-221A. ELSEVIER SCIENCE INC, 2003.
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  - Alexander, K. P., T. Harding, L. Coombs, and E. Peterson. “Are patients properly informed prior to revascularization decisions?.” In Journal of the American College of Cardiology, 41:535A-535A. ELSEVIER SCIENCE INC, 2003.
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  - Lytle, B. L., L. P. Coombs, G. J. Shook, P. A. Cowper, K. P. Alexander, E. D. Peterson, D. B. Mark, and E. R. DeLong. “Home health care for coronary artery disease patients impacts quality of life.” In Journal of the American College of Cardiology, 41:521A-521A. ELSEVIER SCIENCE INC, 2003.
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  - Biswas, M. S., E. L. Eisenstein, and K. P. Alexander. “The right test for the right price.” In Circulation, 106:759–759. LIPPINCOTT WILLIAMS & WILKINS, 2002.
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