Overview
My research focus is on cardiovascular disease management and outcomes in special populations, specifically older adults. Historically there has been a lack of randomized controlled data regarding treatment efficacy and outcomes in this growing population. Because of this, certain therapies may have different risk benefit profiles, which may cause physicians to alter their therapeutic interventions. My research explores evidence based treatment for older adults, including preferences and decision-making as well as frailty and aging assessments in clinical trials and registries. Diagnosis and management of stable ischemic heart disease is also an area of focus.
Current Duke Appointments & Affiliations
Professor of Medicine
·
2015 - Present
Medicine, Cardiology,
Medicine
Member in the Duke Clinical Research Institute
·
1995 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Scholarly Works
Dyslipidemia in Older Adults: Balancing Prevention and Individualized Care.
Journal article J Am Coll Cardiol · May 19, 2026 Full text Link to item CiteCardiovascular Events in US Adults Aged ≥80 Years: Incidence, Risk Factors, and Outcomes.
Journal article Circ Popul Health Outcomes · April 2026 BACKGROUND: Estimating risk and risk factors for cardiovascular disease (CVD) events and mortality following CVD events can inform strategies for lowering risk in older adults. METHODS: We estimated risk factors for the 5-year cumulative incidence of CVD e ... Full text Link to item CiteRepresentation of Older Adults and Women in Randomized Trials of Noninvasive Imaging for Chest Pain.
Journal article Circ Cardiovasc Imaging · October 2025 BACKGROUND: Noninvasive imaging is widely used for both initial diagnosis and guided management of ischemic heart disease. Older adults and women with ischemic heart disease may have different responses to imaging and subsequent treatment outcomes compared ... Full text Link to item CiteRecent Grants
PREVENTABLE
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2019 - 2027Coronary Artery Calcium in the PRagmatic EValuation of evENTs And Benefits of Lipid lowering in the Elderly: CAC PREVENTABLE Ancillary Study
ResearchCo Investigator · Awarded by National Institutes of Health · 2021 - 20271/2 PREEMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2025 - 2027View All Grants
Education
Duke University ·
1992
M.D.