Karen Patton Alexander
Professor of Medicine
My research focus is on cardiovascular disease management and outcomes in special populations, specifically older adults. Historically there has been a lack of randomized controlled data regarding treatment efficacy and outcomes in this growing population. Because of this, certain therapies may have different risk benefit profiles, which may cause physicians to alter their therapeutic interventions. My research explores evidence based treatment for older adults, including preferences and decision-making as well as frailty and aging assessments in clinical trials and registries. Diagnosis and management of stable ischemic heart disease is also an area of focus.
Current Appointments & Affiliations
- Professor of Medicine, Medicine, Cardiology, Medicine 2015
- Member in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 1995
Contact Information
- 200 Morris St, Durham, NC 27701
- Duke Box 3411, Durham, NC 27710
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(919) 668-8871
- Background
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Education, Training, & Certifications
- Cardiology Fellow, Medicine, Duke University 1995 - 1998
- Resident, Internal Medicine, Brigham and Women's Hospital 1993 - 1995
- Intern, Internal Medicine, Brigham and Women's Hospital 1992 - 1993
- M.D., Duke University 1992
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Previous Appointments & Affiliations
- Associate Professor of Medicine, Medicine, Cardiology, Medicine 2010 - 2015
- Associate Professor of Medicine, Medicine, Cardiology, Medicine 2006 - 2010
- Assistant Professor of Medicine, Medicine, Cardiology, Medicine 2000 - 2006
- Associate in the Department of Medicine, Medicine, Cardiology, Medicine 1998 - 2000
- Instructor, Temporary in the Department of Medicine, Medicine, Cardiology, Medicine 1998
- Recognition
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In the News
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AUG 22, 2022 Clinical and Translational Science Institute -
NOV 10, 2015 Duke Today -
NOV 10, 2015
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- Research
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Selected Grants
- PRagmatic EValuation of evENTs And Benefits of Lipid-lowering in oldEr Adults (PREVENTABLE) awarded by National Institutes of Health 2019 - 2027
- Coronary Artery Calcium in the PRagmatic EValuation of evENTs And Benefits of Lipid lowering in the Elderly: CAC PREVENTABLE Ancillary Study awarded by National Institutes of Health 2021 - 2026
- PREVENTABLE Trial Partnership and Meeting Support awarded by Alzheimer's Association 2022
- ISCHEMIA-CKD SDCC awarded by National Institutes of Health 2013 - 2022
- The ISCHEMIA Trial - SDCC awarded by National Institutes of Health 2011 - 2022
- The ISCHEMIA Trial - SDCC awarded by National Institutes of Health 2011 - 2019
- CABANA-AF Trial awarded by National Institutes of Health 2009 - 2017
- NCDR-ACTION awarded by American College of Cardiology Foundation 2008 - 2015
- Duke Cardiovascular CERTs awarded by Agency for Healthcare Research and Quality 2007 - 2012
- Transition of Care for Acute Stroke and Myocardial Infarction Patients awarded by Agency for Healthcare Research and Quality 2010 - 2011
- Safer Antithrombotic Therapy for Elderly ACS Patients awarded by National Institutes of Health 2005 - 2008
- Managed Care Features Affecting Quality for CAD Patients awarded by National Institutes of Health 1999 - 2003
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Damluji, Abdulla A., Daniel E. Forman, Tracy Y. Wang, Joanna Chikwe, Vijay Kunadian, Michael W. Rich, Bessie A. Young, et al. “Management of Acute Coronary Syndrome in the Older Adult Population: A Scientific Statement From the American Heart Association.” Circulation 147, no. 3 (January 17, 2023): e32–62. https://doi.org/10.1161/CIR.0000000000001112.Full Text Link to Item
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Bagai, Akshay, Faeez M. Ali, John Gregson, Karen P. Alexander, Mauricio G. Cohen, Karolina Andersson Sundell, Tabassome Simon, et al. “Multimorbidity, functional impairment, and mortality in older patients stable after prior acute myocardial infarction: Insights from the TIGRIS registry.” Clin Cardiol 45, no. 12 (December 2022): 1277–86. https://doi.org/10.1002/clc.23915.Full Text Link to Item
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Park, Dae Yong, Jiun-Ruey Hu, Karen P. Alexander, and Michael G. Nanna. “Readmission and adverse outcomes after percutaneous coronary intervention in patients with dementia.” J Am Geriatr Soc, November 21, 2022. https://doi.org/10.1111/jgs.18120.Full Text Link to Item
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Chaitman, Bernard R., Derek D. Cyr, Karen P. Alexander, Radosław Pracoń, Kevin R. Bainey, Anoop Mathew, Anjali Acharya, et al. “Cardiovascular and Renal Implications of Myocardial Infarction in the ISCHEMIA-CKD Trial.” Circ Cardiovasc Interv 15, no. 8 (August 2022): e012103. https://doi.org/10.1161/CIRCINTERVENTIONS.122.012103.Full Text Link to Item
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Udell, Jacob A., Di Lu, Akshay Bagai, John A. Dodson, Nihar R. Desai, Gregg C. Fonarow, Abhinav Goyal, et al. “Preexisting frailty and outcomes in older patients with acute myocardial infarction.” Am Heart J 249 (July 2022): 34–44. https://doi.org/10.1016/j.ahj.2022.03.007.Full Text Link to Item
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Alexander, Karen P. “Meaningful Evidence for Anticoagulation in the Gray (Elder) Zone.” Jama Cardiol 7, no. 6 (June 1, 2022): 581–82. https://doi.org/10.1001/jamacardio.2022.0477.Full Text Link to Item
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Wegermann, Zachary K., Michael J. Mack, Suzanne V. Arnold, Christin A. Thompson, Michael Ryan, Candace Gunnarsson, Susan Strong, David J. Cohen, Karen P. Alexander, and J Matthew Brennan. “Anxiety and Depression Following Aortic Valve Replacement.” J Am Heart Assoc 11, no. 9 (May 3, 2022): e024377. https://doi.org/10.1161/JAHA.121.024377.Full Text Link to Item
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Lowenstern, Angela, Karen P. Alexander, Neha J. Pagidipati, C Larry Hill, Patricia A. Pellikka, Lawton S. Cooper, Brooke Alhanti, Udo Hoffmann, Daniel B. Mark, and Pamela S. Douglas. “Presenting Symptoms in Patients Undergoing Coronary Artery Disease Evaluation: Association With Noninvasive Test Results and Clinical Outcomes in the PROMISE Trial.” Circ Cardiovasc Qual Outcomes 15, no. 5 (May 2022): e008298. https://doi.org/10.1161/CIRCOUTCOMES.121.008298.Full Text Link to Item
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Mark, Daniel B., John A. Spertus, Robert Bigelow, Sophia Anderson, Melanie R. Daniels, Kevin J. Anstrom, Khaula N. Baloch, et al. “Comprehensive Quality-of-Life Outcomes With Invasive Versus Conservative Management of Chronic Coronary Disease in ISCHEMIA.” Circulation 145, no. 17 (April 26, 2022): 1294–1307. https://doi.org/10.1161/CIRCULATIONAHA.121.057363.Full Text Link to Item
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Sharma, Abhinav, Kenneth W. Mahaffey, Charles Michael Gibson, Karen A. Hicks, Karen P. Alexander, Maria Ali, Bernard R. Chaitman, et al. “Clinical events classification (CEC) in clinical trials: Report on the current landscape and future directions - proceedings from the CEC Summit 2018.” Am Heart J 246 (April 2022): 93–104. https://doi.org/10.1016/j.ahj.2021.12.012.Full Text Link to Item
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Ekerstad, Niklas, Dariush Javadzadeh, Karen P. Alexander, Olle Bergström, Lars Eurenius, Mats Fredrikson, Gudny Gudnadottir, et al. “Clinical Frailty Scale classes are independently associated with 6-month mortality for patients after acute myocardial infarction.” Eur Heart J Acute Cardiovasc Care 11, no. 2 (February 8, 2022): 89–98. https://doi.org/10.1093/ehjacc/zuab114.Full Text Link to Item
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Rasmussen, Peter Vibe, Jannik Langtved Pallisgaard, Morten Lock Hansen, Gunnar Hilmar Gislason, Christian Torp-Pedersen, Martin Ruwald, Karen P. Alexander, Renato D. Lopes, Sana M. Al-Khatib, and Frederik Dalgaard. “Treatment of older patients with atrial fibrillation by morbidity burden.” Eur Heart J Qual Care Clin Outcomes 8, no. 1 (January 5, 2022): 23–30. https://doi.org/10.1093/ehjqcco/qcaa070.Full Text Link to Item
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Lopez-Sendon, Jose L., Derek D. Cyr, Daniel B. Mark, Sripal Bangalore, Zhen Huang, Harvey D. White, Karen P. Alexander, et al. “Effects of initial invasive vs. initial conservative treatment strategies on recurrent and total cardiovascular events in the ISCHEMIA trial.” European Heart Journal 43, no. 2 (January 2022): 148–49. https://doi.org/10.1093/eurheartj/ehab509.Full Text
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Sachs, B. C., S. R. Rapp, C. E. Kistler, N. Musi, M. A. Supiano, N. M. Pajewski, K. E. Callahan, et al. “The PRagmatic EValuation of evENTs And Benefits of Lipid-lowering in oldEr adults (PREVENTABLE) trial: Study design and procedures for cognitive assessment and adjudication.” Alzheimer’S and Dementia 17, no. S9 (December 1, 2021). https://doi.org/10.1002/alz.054022.Full Text
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Alexander, Karen P., and Pamela S. Douglas. “Chest Pain Redux: Updated and Patient Centered.” Circulation 144, no. 22 (November 30, 2021): 1735–37. https://doi.org/10.1161/CIRCULATIONAHA.121.056714.Full Text Link to Item
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White, Harvey D., Sean M. O’Brien, Karen P. Alexander, William E. Boden, Sripal Bangalore, Jianghao Li, Cholenahally N. Manjunath, et al. “Comparison of Days Alive Out of Hospital With Initial Invasive vs Conservative Management: A Prespecified Analysis of the ISCHEMIA Trial.” Jama Cardiol 6, no. 9 (September 1, 2021): 1023–31. https://doi.org/10.1001/jamacardio.2021.1651.Full Text Link to Item
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Schwartz, Gregory G., Michael Szarek, Vera A. Bittner, Rafael Diaz, Shaun G. Goodman, J Wouter Jukema, Ulf Landmesser, et al. “Lipoprotein(a) and Benefit of PCSK9 Inhibition in Patients With Nominally Controlled LDL Cholesterol.” J Am Coll Cardiol 78, no. 5 (August 3, 2021): 421–33. https://doi.org/10.1016/j.jacc.2021.04.102.Full Text Link to Item
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Alexander, Karen P. “Late-life watercolors, a friendship, and a fall.” J Am Geriatr Soc 69, no. 7 (July 2021): 2021–22. https://doi.org/10.1111/jgs.17144.Full Text Link to Item
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Greenland, Philip, Erin D. Michos, Nicole Redmond, Lawrence J. Fine, Karen P. Alexander, Walter T. Ambrosius, Kirsten Bibbins-Domingo, et al. “Primary Prevention Trial Designs Using Coronary Imaging: A National Heart, Lung, and Blood Institute Workshop.” Jacc Cardiovasc Imaging 14, no. 7 (July 2021): 1454–65. https://doi.org/10.1016/j.jcmg.2020.06.042.Full Text Link to Item
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Lopes, Renato D., Karen P. Alexander, Judith S. Hochman, and David J. Maron. “Response by Lopes et al to Letter Regarding Article, "Initial Invasive Versus Conservative Management of Stable Ischemic Heart Disease Patients With a History of Heart Failure or Left Ventricular Dysfunction: Insights From the ISCHEMIA Trial".” Circulation 143, no. 20 (May 18, 2021): e961–62. https://doi.org/10.1161/CIRCULATIONAHA.121.053672.Full Text Link to Item
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Chaitman, Bernard R., Karen P. Alexander, Derek D. Cyr, Jeffrey S. Berger, Harmony R. Reynolds, Sripal Bangalore, William E. Boden, et al. “Myocardial Infarction in the ISCHEMIA Trial: Impact of Different Definitions on Incidence, Prognosis, and Treatment Comparisons.” Circulation 143, no. 8 (February 23, 2021): 790–804. https://doi.org/10.1161/CIRCULATIONAHA.120.047987.Full Text Link to Item
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Dalgaard, Frederik, Haolin Xu, Roland A. Matsouaka, Andrea M. Russo, Anne B. Curtis, Peter Vibe Rasmussen, Martin H. Ruwald, et al. “Management of Atrial Fibrillation in Older Patients by Morbidity Burden: Insights From Get With The Guidelines-Atrial Fibrillation.” J Am Heart Assoc 9, no. 23 (December 2020): e017024. https://doi.org/10.1161/JAHA.120.017024.Full Text Open Access Copy Link to Item
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Krishnaswami, Ashok, Craig Beavers, Michael P. Dorsch, John A. Dodson, Ruth Masterson Creber, Spyros Kitsiou, Parag Goyal, et al. “Gerotechnology for Older Adults With Cardiovascular Diseases: JACC State-of-the-Art Review.” J Am Coll Cardiol 76, no. 22 (December 1, 2020): 2650–70. https://doi.org/10.1016/j.jacc.2020.09.606.Full Text Link to Item
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Lowenstern, Angela, Karen P. Alexander, and Pamela S. Douglas. “Should We Simplify Computed Tomography Angiography Reporting as Black or White vs Describing All Shades of Gray?-Reply.” Jama Cardiol 5, no. 12 (December 1, 2020): 1450–51. https://doi.org/10.1001/jamacardio.2020.3733.Full Text Link to Item
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Lopes, Renato D., Karen P. Alexander, Susanna R. Stevens, Harmony R. Reynolds, Gregg W. Stone, Ileana L. Piña, Frank W. Rockhold, et al. “Initial Invasive Versus Conservative Management of Stable Ischemic Heart Disease in Patients With a History of Heart Failure or Left Ventricular Dysfunction: Insights From the ISCHEMIA Trial.” Circulation 142, no. 18 (November 3, 2020): 1725–35. https://doi.org/10.1161/CIRCULATIONAHA.120.050304.Full Text Link to Item
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Bangalore, Sripal, David J. Maron, Sean M. O’Brien, Jerome L. Fleg, Evgeny I. Kretov, Carlo Briguori, Upendra Kaul, et al. “Management of Coronary Disease in Patients with Advanced Kidney Disease.” N Engl J Med 382, no. 17 (April 23, 2020): 1608–18. https://doi.org/10.1056/NEJMoa1915925.Full Text Link to Item
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Fanaroff, Alexander C., Ghazala Haque, Betsy Thomas, Allegra E. Stone, Lynn M. Perkins, Matthew Wilson, W Schuyler Jones, et al. “Methods for safety and endpoint ascertainment: identification of adverse events through scrutiny of negatively adjudicated events.” Trials 21, no. 1 (April 9, 2020): 323. https://doi.org/10.1186/s13063-020-04254-w.Full Text Link to Item
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Maron, David J., Judith S. Hochman, Harmony R. Reynolds, Sripal Bangalore, Sean M. O’Brien, William E. Boden, Bernard R. Chaitman, et al. “Initial Invasive or Conservative Strategy for Stable Coronary Disease.” N Engl J Med 382, no. 15 (April 9, 2020): 1395–1407. https://doi.org/10.1056/NEJMoa1915922.Full Text Link to Item
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Spertus, John A., Philip G. Jones, David J. Maron, Sean M. O’Brien, Harmony R. Reynolds, Yves Rosenberg, Gregg W. Stone, et al. “Health-Status Outcomes with Invasive or Conservative Care in Coronary Disease.” N Engl J Med 382, no. 15 (April 9, 2020): 1408–19. https://doi.org/10.1056/NEJMoa1916370.Full Text Link to Item
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Lowenstern, Angela, Karen P. Alexander, C Larry Hill, Brooke Alhanti, Patricia A. Pellikka, Michael G. Nanna, Rajendra H. Mehta, et al. “Age-Related Differences in the Noninvasive Evaluation for Possible Coronary Artery Disease: Insights From the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) Trial.” Jama Cardiol 5, no. 2 (February 1, 2020): 193–201. https://doi.org/10.1001/jamacardio.2019.4973.Full Text Link to Item
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Wenger, Nanette K., and Karen P. Alexander. “Not your grandparents' cardiac care: The future of geriatric cardiology.” Clin Cardiol 43, no. 2 (February 2020): 90–91. https://doi.org/10.1002/clc.23270.Full Text Link to Item
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Damluji, Abdulla A., Daniel E. Forman, Sean van Diepen, Karen P. Alexander, Robert L. Page, Scott L. Hummel, Venu Menon, et al. “Older Adults in the Cardiac Intensive Care Unit: Factoring Geriatric Syndromes in the Management, Prognosis, and Process of Care: A Scientific Statement From the American Heart Association.” Circulation 141, no. 2 (January 14, 2020): e6–32. https://doi.org/10.1161/CIR.0000000000000741.Full Text Link to Item
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Starks, Monique Anderson, and Karen Alexander. “In Anticipation of the Inevitable: Preparing Older Americans for Cardiac Arrest.” J Am Geriatr Soc 68, no. 1 (January 2020): 9–10. https://doi.org/10.1111/jgs.16269.Full Text Link to Item
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Nanna, Michael G., Eric D. Peterson, Angie Wu, Tina Harding, Anthony N. Galanos, Lisa Wruck, and Karen P. Alexander. “Age, knowledge, preferences, and risk tolerance for invasive cardiac care.” Am Heart J 219 (January 2020): 99–108. https://doi.org/10.1016/j.ahj.2019.09.008.Full Text Link to Item
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Goyal, Parag, Eiran Z. Gorodeski, Kelsey M. Flint, Deena S. Goldwater, John A. Dodson, Jonathan Afilalo, Mathew S. Maurer, Michael W. Rich, Karen P. Alexander, and Scott L. Hummel. “Perspectives on Implementing a Multidomain Approach to Caring for Older Adults With Heart Failure.” J Am Geriatr Soc 67, no. 12 (December 2019): 2593–99. https://doi.org/10.1111/jgs.16183.Full Text Link to Item
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Newman, Jonathan D., Karen P. Alexander, Xiangqiong Gu, Sean M. O’Brien, William E. Boden, Sajeev C. Govindan, Roxy Senior, et al. “Baseline Predictors of Low-Density Lipoprotein Cholesterol and Systolic Blood Pressure Goal Attainment After 1 Year in the ISCHEMIA Trial.” Circ Cardiovasc Qual Outcomes 12, no. 11 (November 2019): e006002. https://doi.org/10.1161/CIRCOUTCOMES.119.006002.Full Text Link to Item
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Nanna, Michael G., Alexandra M. Hajduk, Harlan M. Krumholz, Terrence E. Murphy, Rachel P. Dreyer, Karen P. Alexander, Mary Geda, et al. “Sex-Based Differences in Presentation, Treatment, and Complications Among Older Adults Hospitalized for Acute Myocardial Infarction: The SILVER-AMI Study.” Circ Cardiovasc Qual Outcomes 12, no. 10 (October 2019): e005691. https://doi.org/10.1161/CIRCOUTCOMES.119.005691.Full Text Link to Item
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Bagai, Akshay, Anita Y. Chen, Jacob A. Udell, John A. Dodson, David D. McManus, Mathew S. Maurer, Jonathan R. Enriquez, et al. “Association of Cognitive Impairment With Treatment and Outcomes in Older Myocardial Infarction Patients: A Report From the NCDR Chest Pain-MI Registry.” J Am Heart Assoc 8, no. 17 (September 3, 2019): e012929. https://doi.org/10.1161/JAHA.119.012929.Full Text Link to Item
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Alexander, Karen P., and John H. Alexander. “Safe and Effective Anticoagulation: What Does Drug Concentration Add?” J Am Geriatr Soc 67, no. 9 (September 2019): 1772–73. https://doi.org/10.1111/jgs.15981.Full Text Link to Item
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Ray, Kausik K., Helen M. Colhoun, Michael Szarek, Marie Baccara-Dinet, Deepak L. Bhatt, Vera A. Bittner, Andrzej J. Budaj, et al. “Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: a prespecified analysis of the ODYSSEY OUTCOMES randomised controlled trial.” Lancet Diabetes Endocrinol 7, no. 8 (August 2019): 618–28. https://doi.org/10.1016/S2213-8587(19)30158-5.Full Text Link to Item
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Krishnaswami, Ashok, Michael A. Steinman, Parag Goyal, Andrew R. Zullo, Timothy S. Anderson, Kim K. Birtcher, Sarah J. Goodlin, et al. “Deprescribing in Older Adults With Cardiovascular Disease.” J Am Coll Cardiol 73, no. 20 (May 28, 2019): 2584–95. https://doi.org/10.1016/j.jacc.2019.03.467.Full Text Link to Item
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Dodson, John A., Alexandra M. Hajduk, Terrence E. Murphy, Mary Geda, Harlan M. Krumholz, Sui Tsang, Michael G. Nanna, et al. “Thirty-Day Readmission Risk Model for Older Adults Hospitalized With Acute Myocardial Infarction.” Circ Cardiovasc Qual Outcomes 12, no. 5 (May 2019): e005320. https://doi.org/10.1161/CIRCOUTCOMES.118.005320.Full Text Link to Item
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Fanaroff, Alexander C., Kristi Prather, Amanda Brucker, Daniel Wojdyla, Linda Davidson-Ray, Daniel B. Mark, Redford B. Williams, et al. “Relationship Between Optimism and Outcomes in Patients With Chronic Angina Pectoris.” Am J Cardiol 123, no. 9 (May 1, 2019): 1399–1405. https://doi.org/10.1016/j.amjcard.2019.01.036.Full Text Link to Item
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Kaul, Padma, Karen P. Alexander, E Magnus Ohman, Anamaria Savu, Matthew T. Roe, Shaun G. Goodman, Keith A. Fox, et al. “Sex And Prognostic Significance of Self-Reported Frailty in Non-ST-Segment Elevation Acute Coronary Syndromes: Insights From the TRILOGY ACS Trial.” Can J Cardiol 35, no. 4 (April 2019): 430–37. https://doi.org/10.1016/j.cjca.2018.12.035.Full Text Link to Item
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“Correction.” Jacc: Cardiovascular Interventions 12, no. 7 (April 2019): 695–96. https://doi.org/10.1016/j.jcin.2019.03.009.Full Text
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Hochman, Judith S., Harmony R. Reynolds, Sripal Bangalore, Sean M. O’Brien, Karen P. Alexander, Roxy Senior, William E. Boden, et al. “Baseline Characteristics and Risk Profiles of Participants in the ISCHEMIA Randomized Clinical Trial.” Jama Cardiol 4, no. 3 (March 1, 2019): 273–86. https://doi.org/10.1001/jamacardio.2019.0014.Full Text Link to Item
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Fanaroff, Alexander C., Robert Clare, Karen S. Pieper, Kenneth W. Mahaffey, Chiara Melloni, Jennifer B. Green, John H. Alexander, et al. “Frequency, Regional Variation, and Predictors of Undetermined Cause of Death in Cardiometabolic Clinical Trials: A Pooled Analysis of 9259 Deaths in 9 Trials.” Circulation 139, no. 7 (February 12, 2019): 863–73. https://doi.org/10.1161/CIRCULATIONAHA.118.037202.Full Text Link to Item
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Alexander, Karen P., Marc A. Brouwer, Hillary Mulder, Dragos Vinereanu, Renato D. Lopes, Marco Proietti, Sana M. Al-Khatib, et al. “Outcomes of apixaban versus warfarin in patients with atrial fibrillation and multi-morbidity: Insights from the ARISTOTLE trial.” Am Heart J 208 (February 2019): 123–31. https://doi.org/10.1016/j.ahj.2018.09.017.Full Text Link to Item
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Afilalo, Jonathan, Abhinav Sharma, Shuaiqi Zhang, J Matthew Brennan, Fred H. Edwards, Michael J. Mack, James B. McClurken, et al. “Gait Speed and 1-Year Mortality Following Cardiac Surgery: A Landmark Analysis From the Society of Thoracic Surgeons Adult Cardiac Surgery Database.” J Am Heart Assoc 7, no. 23 (December 4, 2018): e010139. https://doi.org/10.1161/JAHA.118.010139.Full Text Link to Item
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Schwartz, Gregory G., P Gabriel Steg, Michael Szarek, Deepak L. Bhatt, Vera A. Bittner, Rafael Diaz, Jay M. Edelberg, et al. “Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome.” N Engl J Med 379, no. 22 (November 29, 2018): 2097–2107. https://doi.org/10.1056/NEJMoa1801174.Full Text Link to Item
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Dodson, John A., Judith S. Hochman, Matthew T. Roe, Anita Y. Chen, Sarwat I. Chaudhry, Stuart Katz, Hua Zhong, et al. “The Association of Frailty With In-Hospital Bleeding Among Older Adults With Acute Myocardial Infarction: Insights From the ACTION Registry.” Jacc Cardiovasc Interv 11, no. 22 (November 26, 2018): 2287–96. https://doi.org/10.1016/j.jcin.2018.08.028.Full Text Link to Item
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Bangalore, Sripal, David J. Maron, Jerome L. Fleg, Sean M. O’Brien, Charles A. Herzog, Gregg W. Stone, Daniel B. Mark, et al. “International Study of Comparative Health Effectiveness with Medical and Invasive Approaches-Chronic Kidney Disease (ISCHEMIA-CKD): Rationale and design.” Am Heart J 205 (November 2018): 42–52. https://doi.org/10.1016/j.ahj.2018.07.023.Full Text Link to Item
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Ekerstad, Niklas, Staffan Pettersson, Karen Alexander, David Andersson, Sofia Eriksson, Magnus Janzon, Marcus Lindenberger, Eva Swahn, and Joakim Alfredsson. “Frailty as an instrument for evaluation of elderly patients with non-ST-segment elevation myocardial infarction: A follow-up after more than 5 years.” Eur J Prev Cardiol 25, no. 17 (November 2018): 1813–21. https://doi.org/10.1177/2047487318799438.Full Text Link to Item
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Hernandez, Adrian F., Jennifer B. Green, Salim Janmohamed, Ralph B. D’Agostino, Christopher B. Granger, Nigel P. Jones, Lawrence A. Leiter, et al. “Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial.” Lancet 392, no. 10157 (October 27, 2018): 1519–29. https://doi.org/10.1016/S0140-6736(18)32261-X.Full Text Link to Item
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Krishnaswami, Ashok, Dae Hyun Kim, Charles E. McCulloch, Daniel E. Forman, Mathew S. Maurer, Karen P. Alexander, and Michael W. Rich. “Individual and Joint Effects of Pulse Pressure and Blood Pressure Treatment Intensity on Serious Adverse Events in the SPRINT Trial.” Am J Med 131, no. 10 (October 2018): 1220-1227.e1. https://doi.org/10.1016/j.amjmed.2018.05.027.Full Text Link to Item
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Patel, Ashish, Shaun G. Goodman, Andrew T. Yan, Karen P. Alexander, Camilla L. Wong, Asim N. Cheema, Jacob A. Udell, et al. “Frailty and Outcomes After Myocardial Infarction: Insights From the CONCORDANCE Registry.” J Am Heart Assoc 7, no. 18 (September 18, 2018): e009859. https://doi.org/10.1161/JAHA.118.009859.Full Text Link to Item
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ISCHEMIA Trial Research Group, Yves, David J. Maron, Judith S. Hochman, Sean M. O’Brien, Harmony R. Reynolds, William E. Boden, Gregg W. Stone, et al. “International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA) trial: Rationale and design.” Am Heart J 201 (July 2018): 124–35. https://doi.org/10.1016/j.ahj.2018.04.011.Full Text Link to Item
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Miller, Andrew P., Mathew Maurer, and Karen P. Alexander. “Geriatric Cardiology: Two Decades of Progress and Strategy for the Future.” J Am Coll Cardiol 71, no. 25 (June 26, 2018): 2970–73. https://doi.org/10.1016/j.jacc.2018.05.014.Full Text Link to Item
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Madhavan, Mahesh V., Bernard J. Gersh, Karen P. Alexander, Christopher B. Granger, and Gregg W. Stone. “Coronary Artery Disease in Patients ≥80 Years of Age.” J Am Coll Cardiol 71, no. 18 (May 8, 2018): 2015–40. https://doi.org/10.1016/j.jacc.2017.12.068.Full Text Link to Item
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Bangalore, Sripal, David J. Maron, Harmony R. Reynolds, Gregg W. Stone, Sean M. O’Brien, Karen P. Alexander, and Judith S. Hochman. “ISCHEMIA: Establishing the Primary End Point.” Circ Cardiovasc Qual Outcomes 11, no. 5 (May 2018): e004791. https://doi.org/10.1161/CIRCOUTCOMES.118.004791.Full Text Link to Item
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Gorodeski, Eiran Z., Parag Goyal, Scott L. Hummel, Ashok Krishnaswami, Sarah J. Goodlin, Linda L. Hart, Daniel E. Forman, et al. “Domain Management Approach to Heart Failure in the Geriatric Patient: Present and Future.” J Am Coll Cardiol 71, no. 17 (May 1, 2018): 1921–36. https://doi.org/10.1016/j.jacc.2018.02.059.Full Text Link to Item
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Patel, Krishna K., Suzanne V. Arnold, Philip G. Jones, Mohammed Qintar, Karen P. Alexander, and John A. Spertus. “Relation of Age and Health-Related Quality of Life to Invasive Versus Ischemia-Guided Management of Patients with Non-ST Elevation Myocardial Infarction.” Am J Cardiol 121, no. 7 (April 1, 2018): 789–95. https://doi.org/10.1016/j.amjcard.2017.12.034.Full Text Link to Item
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Flint, Kelsey, Kevin Kennedy, Suzanne V. Arnold, John A. Dodson, Sharon Cresci, and Karen P. Alexander. “Slow Gait Speed and Cardiac Rehabilitation Participation in Older Adults After Acute Myocardial Infarction.” J Am Heart Assoc 7, no. 5 (February 24, 2018). https://doi.org/10.1161/JAHA.117.008296.Full Text Link to Item
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Guimarães, Patrícia O., Sergio Leonardi, Zhen Huang, Lars Wallentin, Frans Van de Werf, Philip E. Aylward, Claes Held, et al. “Clinical features and outcomes of patients with type 2 myocardial infarction: Insights from the Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRACER) trial.” Am Heart J 196 (February 2018): 28–35. https://doi.org/10.1016/j.ahj.2017.10.007.Full Text Link to Item
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Cooper, Lauren B., Bradley G. Hammill, Larry A. Allen, JoAnn Lindenfeld, Robert J. Mentz, Joseph G. Rogers, Carmelo A. Milano, Chetan B. Patel, Karen P. Alexander, and Adrian F. Hernandez. “Assessing Frailty in Patients Undergoing Destination Therapy Left Ventricular Assist Device: Observations from Interagency Registry for Mechanically Assisted Circulatory Support.” Asaio J 64, no. 1 (2018): 16–23. https://doi.org/10.1097/MAT.0000000000000600.Full Text Link to Item
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Krishnaswami, Ashok, Mathew S. Maurer, and Karen P. Alexander. “Contextualizing Myocardial Infarction: Comorbidities and Priorities in Older Adults.” Am J Med 130, no. 10 (October 2017): 1144–47. https://doi.org/10.1016/j.amjmed.2017.05.043.Full Text Link to Item
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Alexander, Karen P. “Walking as a Window to Risk and Resiliency.” Circulation 136, no. 7 (August 15, 2017): 644–45. https://doi.org/10.1161/CIRCULATIONAHA.117.028889.Full Text Link to Item
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Bagai, Akshay, Karen P. Alexander, Jeffrey S. Berger, Roxy Senior, Chakkanalil Sajeev, Radoslaw Pracon, Kreton Mavromatis, et al. “Use of troponin assay 99th percentile as the decision level for myocardial infarction diagnosis.” Am Heart J 190 (August 2017): 135–39. https://doi.org/10.1016/j.ahj.2017.04.016.Full Text Link to Item
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Posenau, J Trevor, Daniel M. Wojdyla, Linda K. Shaw, Karen P. Alexander, E Magnus Ohman, Manesh R. Patel, Peter K. Smith, and Sunil V. Rao. “Revascularization Strategies and Outcomes in Elderly Patients With Multivessel Coronary Disease.” Ann Thorac Surg 104, no. 1 (July 2017): 107–15. https://doi.org/10.1016/j.athoracsur.2016.10.053.Full Text Link to Item
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Neeland, Ian J., Sandeep R. Das, DaJuanicia N. Simon, Deborah B. Diercks, Karen P. Alexander, Tracy Y. Wang, and James A. de Lemos. “The obesity paradox, extreme obesity, and long-term outcomes in older adults with ST-segment elevation myocardial infarction: results from the NCDR.” Eur Heart J Qual Care Clin Outcomes 3, no. 3 (July 1, 2017): 183–91. https://doi.org/10.1093/ehjqcco/qcx010.Full Text Link to Item
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Alexander, Karen P. “Low-Hanging Fruit for a Healthy Old Age.” J Am Coll Cardiol 69, no. 25 (June 27, 2017): 3027–28. https://doi.org/10.1016/j.jacc.2017.05.025.Full Text Link to Item
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Fanaroff, Alexander C., Stefan K. James, Giora Weisz, Kristi Prather, Kevin J. Anstrom, Daniel B. Mark, Ori Ben-Yehuda, Karen P. Alexander, Gregg W. Stone, and E Magnus Ohman. “Ranolazine After Incomplete Percutaneous Coronary Revascularization in Patients With Versus Without Diabetes Mellitus: RIVER-PCI Trial.” J Am Coll Cardiol 69, no. 18 (May 9, 2017): 2304–13. https://doi.org/10.1016/j.jacc.2017.02.056.Full Text Link to Item
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Guimarães, Patrícia O., Renato D. Lopes, Susanna R. Stevens, André Zimerman, Lisa Wruck, Stefan K. James, Ghazala Haque, Roberto Rocha C. V. Giraldez, John H. Alexander, and Karen P. Alexander. “Reporting Clinical End Points and Safety Events in an Acute Coronary Syndrome Trial: Results With Integrated Collection.” J Am Heart Assoc 6, no. 4 (April 24, 2017). https://doi.org/10.1161/JAHA.117.005490.Full Text Link to Item
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Alexander, Karen P. “Assessing the Utility of Transcatheter Aortic Valve Replacement.” Jama Cardiol 2, no. 4 (April 1, 2017): 416–17. https://doi.org/10.1001/jamacardio.2016.5549.Full Text Link to Item
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Sharma, Abhinav, and Karen P. Alexander. “Natriuretic Peptides in Older Patients With Heart Failure: A Look Into the Seeds of Time.” Journal of the American Geriatrics Society 65, no. 4 (April 2017): 691–92. https://doi.org/10.1111/jgs.14762.Full Text
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Otto, Catherine M., Dharam J. Kumbhani, Karen P. Alexander, John H. Calhoon, Milind Y. Desai, Sanjay Kaul, James C. Lee, Carlos E. Ruiz, and Christina M. Vassileva. “2017 ACC Expert Consensus Decision Pathway for Transcatheter Aortic Valve Replacement in the Management of Adults With Aortic Stenosis: A Report of the American College of Cardiology Task Force on Clinical Expert Consensus Documents.” J Am Coll Cardiol 69, no. 10 (March 14, 2017): 1313–46. https://doi.org/10.1016/j.jacc.2016.12.006.Full Text Link to Item
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Alexander, Karen P. “Putting the Acute Coronary Syndrome in Context After 80 Years of Age.” Circulation 135, no. 1 (January 3, 2017): 5–6. https://doi.org/10.1161/CIRCULATIONAHA.116.022148.Full Text Link to Item
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Alexander, Karen P. “Identifying the frailty phenotype: The evidence for good enough.” Am Heart J 182 (December 2016): 144–45. https://doi.org/10.1016/j.ahj.2016.09.005.Full Text Link to Item
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Rich, Michael W., Deborah A. Chyun, Adam H. Skolnick, Karen P. Alexander, Daniel E. Forman, Dalane W. Kitzman, Mathew S. Maurer, et al. “Knowledge Gaps in Cardiovascular Care of Older Adults: A Scientific Statement from the American Heart Association, American College of Cardiology, and American Geriatrics Society: Executive Summary.” J Am Geriatr Soc 64, no. 11 (November 2016): 2185–92. https://doi.org/10.1111/jgs.14576.Full Text Link to Item
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Arnold, Suzanne V., Anna Grodzinsky, Kensey L. Gosch, Mikhail Kosiborod, Philip G. Jones, Tracie Breeding, Arooge Towheed, John Beltrame, Karen P. Alexander, and John A. Spertus. “Predictors of Physician Under-Recognition of Angina in Outpatients With Stable Coronary Artery Disease.” Circ Cardiovasc Qual Outcomes 9, no. 5 (September 2016): 554–59. https://doi.org/10.1161/CIRCOUTCOMES.116.002781.Full Text Link to Item
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Forman, Daniel E., and Karen P. Alexander. “Frailty: A Vital Sign for Older Adults With Cardiovascular Disease.” Can J Cardiol 32, no. 9 (September 2016): 1082–87. https://doi.org/10.1016/j.cjca.2016.05.015.Full Text Link to Item
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Alexander, Karen P., Michael W. Rich, Daniel E. Forman, Nanette K. Wenger, John A. Dodson, Joseph S. Alpert, James N. Kirkpatrick, and Mathew S. Maurer. “Top 10 List for the Cardiovascular Care of Older Adults.” Am J Med 129, no. 9 (September 2016): 901–2. https://doi.org/10.1016/j.amjmed.2016.04.031.Full Text Link to Item
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Armaganijan, Luciana V., Karen P. Alexander, Zhen Huang, Pierluigi Tricoci, Claes Held, Frans Van de Werf, Paul W. Armstrong, et al. “Effect of age on efficacy and safety of vorapaxar in patients with non-ST-segment elevation acute coronary syndrome: Insights from the Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRACER) trial.” Am Heart J 178 (August 2016): 176–84. https://doi.org/10.1016/j.ahj.2016.05.012.Full Text Link to Item
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Afilalo, Jonathan, Sunghee Kim, Sean O’Brien, J Matthew Brennan, Fred H. Edwards, Michael J. Mack, James B. McClurken, et al. “Gait Speed and Operative Mortality in Older Adults Following Cardiac Surgery.” Jama Cardiol 1, no. 3 (June 1, 2016): 314–21. https://doi.org/10.1001/jamacardio.2016.0316.Full Text Link to Item
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White, Harvey D., Cynthia M. Westerhout, Karen P. Alexander, Matthew T. Roe, Kenneth J. Winters, Derek D. Cyr, Keith Aa Fox, et al. “Frailty is associated with worse outcomes in non-ST-segment elevation acute coronary syndromes: Insights from the TaRgeted platelet Inhibition to cLarify the Optimal strateGy to medicallY manage Acute Coronary Syndromes (TRILOGY ACS) trial.” Eur Heart J Acute Cardiovasc Care 5, no. 3 (June 2016): 231–42. https://doi.org/10.1177/2048872615581502.Full Text Link to Item
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Rich, Michael W., Deborah A. Chyun, Adam H. Skolnick, Karen P. Alexander, Daniel E. Forman, Dalane W. Kitzman, Mathew S. Maurer, et al. “Knowledge Gaps in Cardiovascular Care of the Older Adult Population: A Scientific Statement From the American Heart Association, American College of Cardiology, and American Geriatrics Society.” J Am Coll Cardiol 67, no. 20 (May 24, 2016): 2419–40. https://doi.org/10.1016/j.jacc.2016.03.004.Full Text Link to Item
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Rich, Michael W., Deborah A. Chyun, Adam H. Skolnick, Karen P. Alexander, Daniel E. Forman, Dalane W. Kitzman, Mathew S. Maurer, et al. “Knowledge Gaps in Cardiovascular Care of the Older Adult Population: A Scientific Statement From the American Heart Association, American College of Cardiology, and American Geriatrics Society.” Circulation 133, no. 21 (May 24, 2016): 2103–22. https://doi.org/10.1161/CIR.0000000000000380.Full Text Link to Item
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Alfredsson, Joakim, and Karen P. Alexander. “Multiple Chronic Conditions in Older Adults with Acute Coronary Syndromes.” Clin Geriatr Med 32, no. 2 (May 2016): 291–303. https://doi.org/10.1016/j.cger.2016.01.009.Full Text Link to Item
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Alexander, Karen P., Olena Stadnyuk, Suzanne V. Arnold, Daniel B. Mark, E Magnus Ohman, and Kevin J. Anstrom. “Assessing Quality of Life and Medical Care in Chronic Angina: An Internet Survey.” Interact J Med Res 5, no. 2 (April 28, 2016): e12. https://doi.org/10.2196/ijmr.4971.Full Text Link to Item
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Kragholm, Kristian, Sarah A. Goldstein, Qinghong Yang, Renato D. Lopes, Phillip J. Schulte, Gwen M. Bernacki, Harvey D. White, et al. “Trends in Enrollment, Clinical Characteristics, Treatment, and Outcomes According to Age in Non-ST-Segment-Elevation Acute Coronary Syndromes Clinical Trials.” Circulation 133, no. 16 (April 19, 2016): 1560–73. https://doi.org/10.1161/CIRCULATIONAHA.115.017299.Full Text Link to Item
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Alfredsson, Joakim, Amanda Stebbins, J Matthew Brennan, Roland Matsouaka, Jonathan Afilalo, Eric D. Peterson, Sreekanth Vemulapalli, et al. “Gait Speed Predicts 30-Day Mortality After Transcatheter Aortic Valve Replacement: Results From the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry.” Circulation 133, no. 14 (April 5, 2016): 1351–59. https://doi.org/10.1161/CIRCULATIONAHA.115.020279.Full Text Link to Item
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Melloni, Chiara, and Karen P. Alexander. “Exploring the Nexus Between Chronic Kidney Disease and Cardiovascular Disease.” Eur Heart J Qual Care Clin Outcomes 2, no. 2 (April 1, 2016): 62–63. https://doi.org/10.1093/ehjqcco/qcw009.Full Text Link to Item
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Zimerman, André, Renato D. Lopes, Amanda L. Stebbins, Patrícia O. Guimarães, Ghazala Haque, Chiara Melloni, Kathleen Trollinger, et al. “Pooled analysis of adverse event collection from 4 acute coronary syndrome trials.” Am Heart J 174 (April 2016): 60–67. https://doi.org/10.1016/j.ahj.2016.01.003.Full Text Link to Item
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Dodson, John A., Suzanne V. Arnold, Kensey L. Gosch, Thomas M. Gill, John A. Spertus, Harlan M. Krumholz, Michael W. Rich, et al. “Slow Gait Speed and Risk of Mortality or Hospital Readmission After Myocardial Infarction in the Translational Research Investigating Underlying Disparities in Recovery from Acute Myocardial Infarction: Patients' Health Status Registry.” J Am Geriatr Soc 64, no. 3 (March 2016): 596–601. https://doi.org/10.1111/jgs.14016.Full Text Link to Item
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Dai, Xuming, Jan Busby-Whitehead, Daniel E. Forman, and Karen P. Alexander. “Stable ischemic heart disease in the older adults.” J Geriatr Cardiol 13, no. 2 (February 2016): 109–14. https://doi.org/10.11909/j.issn.1671-5411.2016.02.013.Full Text Open Access Copy Link to Item
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Dai, Xuming, Jan Busby-Whitehead, and Karen P. Alexander. “Acute coronary syndrome in the older adults.” J Geriatr Cardiol 13, no. 2 (February 2016): 101–8. https://doi.org/10.11909/j.issn.1671-5411.2016.02.012.Full Text Link to Item
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Weisz, Giora, Philippe Généreux, Andres Iñiguez, Aleksander Zurakowski, Michael Shechter, Karen P. Alexander, Ovidiu Dressler, et al. “Ranolazine in patients with incomplete revascularisation after percutaneous coronary intervention (RIVER-PCI): a multicentre, randomised, double-blind, placebo-controlled trial.” Lancet 387, no. 10014 (January 9, 2016): 136–45. https://doi.org/10.1016/S0140-6736(15)00459-6.Full Text Link to Item
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Alexander, Karen P., Giora Weisz, Kristi Prather, Stefan James, Daniel B. Mark, Kevin J. Anstrom, Linda Davidson-Ray, et al. “Effects of Ranolazine on Angina and Quality of Life After Percutaneous Coronary Intervention With Incomplete Revascularization: Results From the Ranolazine for Incomplete Vessel Revascularization (RIVER-PCI) Trial.” Circulation 133, no. 1 (January 5, 2016): 39–47. https://doi.org/10.1161/CIRCULATIONAHA.115.019768.Full Text Link to Item
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Forman, Daniel E., Karen Alexander, Ralph G. Brindis, Anne B. Curtis, Mathew Maurer, Michael W. Rich, Laurence Sperling, and Nanette K. Wenger. “Improved Cardiovascular Disease Outcomes in Older Adults.” F1000res 5 (2016). https://doi.org/10.12688/f1000research.7088.1.Full Text Link to Item
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Qintar, Mohammed, John A. Spertus, Kensey L. Gosch, John Beltrame, Faraz Kureshi, Ali Shafiq, Tracie Breeding, Karen P. Alexander, and Suzanne V. Arnold. “Effect of angina under-recognition on treatment in outpatients with stable ischaemic heart disease.” Eur Heart J Qual Care Clin Outcomes 2, no. 3 (2016): 208–14. https://doi.org/10.1093/ehjqcco/qcw016.Full Text Link to Item
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Wayangankar, S. A., M. T. Roe, A. Y. Chen, R. S. Gupta, R. P. Giugliano, L. K. Newby, J. A. de Lemos, K. P. Alexander, T. A. Sanborn, and J. F. Saucedo. “Trends in use of anti-thrombotic agents and outcomes in patients with non-ST-segment elevation myocardial infarction (NSTEMI) managed with an invasive strategy.” Indian Heart J 68, no. 4 (2016): 464–72. https://doi.org/10.1016/j.ihj.2015.09.036.Full Text Link to Item
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Kang, Hyun-Jae, Dajuanicia Simon, Tracy Y. Wang, Karen P. Alexander, Myung Ho Jeong, Hyo-Soo Kim, Eric R. Bates, et al. “The Contemporary Use of Angiography and Revascularization Among Patients With Non-ST-Segment Elevation Myocardial Infarction in the United States Compared With South Korea.” Clin Cardiol 38, no. 12 (December 2015): 708–14. https://doi.org/10.1002/clc.22475.Full Text Link to Item
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Shen, Lan, Bimal R. Shah, Shuang Li, Laine Thomas, Tracy Y. Wang, Karen P. Alexander, Eric D. Peterson, Ben He, and Matthew T. Roe. “The Association of Transfer Rate From Hospitals Without Revascularization Capabilities and Mortality Risk for Older Non-ST-Segment Elevation Myocardial Infarction Patients.” Clin Cardiol 38, no. 12 (December 2015): 733–39. https://doi.org/10.1002/clc.22480.Full Text Link to Item
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Skolnick, Adam H., and Karen P. Alexander. “Older Adults in Clinical Research and Drug Development: Closing the Geriatric Gap.” Circ Cardiovasc Qual Outcomes 8, no. 6 (November 2015): 631–33. https://doi.org/10.1161/CIRCOUTCOMES.115.002158.Full Text Link to Item
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Swiger, Kristopher J., Seth S. Martin, Fengming Tang, Michael J. Blaha, Roger S. Blumenthal, Karen P. Alexander, Suzanne V. Arnold, and John A. Spertus. “Cognitive and Physical Function by Statin Exposure in Elderly Individuals Following Acute Myocardial Infarction.” Clin Cardiol 38, no. 8 (August 2015): 455–61. https://doi.org/10.1002/clc.22423.Full Text Link to Item
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Gupta, Aakriti, Philip Chui, Shengfan Zhou, John A. Spertus, Mary Geda, Nancy Lorenze, Ike Lee, et al. “Frequency and Effects of Excess Dosing of Anticoagulants in Patients ≤55 Years With Acute Myocardial Infarction Who Underwent Percutaneous Coronary Intervention (from the VIRGO Study).” Am J Cardiol 116, no. 1 (July 1, 2015): 1–7. https://doi.org/10.1016/j.amjcard.2015.03.032.Full Text Link to Item
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Arnold, Suzanne V., Shu-Xia Li, Karen P. Alexander, John A. Spertus, Brahmajee K. Nallamothu, Jeptha P. Curtis, Mikhail Kosiborod, et al. “Hospital variability in use of anticoagulant strategies during acute myocardial infarction treated with an early invasive strategy.” J Am Heart Assoc 4, no. 6 (June 15, 2015): e002009. https://doi.org/10.1161/JAHA.115.002009.Full Text Link to Item
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O’Brien, Emily C., DaJuanicia N. Simon, Matthew T. Roe, Tracy Y. Wang, Eric D. Peterson, and Karen P. Alexander. “Statin Treatment by Low-Density Lipoprotein Cholesterol Levels in Patients With Non-ST-Segment Elevation Myocardial Infarction/Unstable Angina Pectoris (from the CRUSADE Registry).” Am J Cardiol 115, no. 12 (June 15, 2015): 1655–60. https://doi.org/10.1016/j.amjcard.2015.03.007.Full Text Link to Item
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Lopes, Renato D., S Michael Gharacholou, DaJuanicia N. Holmes, Laine Thomas, Tracy Y. Wang, Matthew T. Roe, Eric D. Peterson, and Karen P. Alexander. “Cumulative incidence of death and rehospitalization among the elderly in the first year after NSTEMI.” Am J Med 128, no. 6 (June 2015): 582–90. https://doi.org/10.1016/j.amjmed.2014.12.032.Full Text Link to Item
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Mehta, Rajendra H., Anita Y. Chen, Karen P. Alexander, E Magnus Ohman, Matthew T. Roe, and Eric D. Peterson. “Doing the right things and doing them the right way: association between hospital guideline adherence, dosing safety, and outcomes among patients with acute coronary syndrome.” Circulation 131, no. 11 (March 17, 2015): 980–87. https://doi.org/10.1161/CIRCULATIONAHA.114.013451.Full Text Link to Item
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Fihn, Stephan D., James C. Blankenship, Karen P. Alexander, John A. Bittl, John G. Byrne, Barbara J. Fletcher, Gregg C. Fonarow, et al. “2014 ACC/AHA/AATS/PCNA/SCAI/STS focused update of the guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines, and the American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons.” J Thorac Cardiovasc Surg 149, no. 3 (March 2015): e5-23. https://doi.org/10.1016/j.jtcvs.2014.11.002.Full Text Link to Item
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Lytle, Barbara L., Shuang Li, David M. Lofthus, Laine Thomas, Jennifer L. Poteat, Deepak L. Bhatt, Christopher P. Cannon, et al. “Targeted versus standard feedback: results from a randomized quality improvement trial.” Am Heart J 169, no. 1 (January 2015): 132-41.e2. https://doi.org/10.1016/j.ahj.2014.08.017.Full Text Link to Item
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Taha, Salma, Fabrizio D’Ascenzo, Claudio Moretti, Pierluigi Omedè, Antonio Montefusco, Richard G. Bach, Karen P. Alexander, et al. “Accuracy of bleeding scores for patients presenting with myocardial infarction: a meta-analysis of 9 studies and 13 759 patients.” Postepy Kardiol Interwencyjnej 11, no. 3 (2015): 182–90. https://doi.org/10.5114/pwki.2015.54011.Full Text Link to Item
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Fihn, Stephan D., James C. Blankenship, Karen P. Alexander, John A. Bittl, John G. Byrne, Barbara J. Fletcher, Gregg C. Fonarow, et al. “2014 ACC/AHA/AATS/PCNA/SCAI/STS focused update of the guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines, and the American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons.” J Am Coll Cardiol 64, no. 18 (November 4, 2014): 1929–49. https://doi.org/10.1016/j.jacc.2014.07.017.Full Text Link to Item
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Fihn, Stephan D., James C. Blankenship, Karen P. Alexander, John A. Bittl, John G. Byrne, Barbara J. Fletcher, Gregg C. Fonarow, et al. “2014 ACC/AHA/AATS/PCNA/SCAI/STS focused update of the guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines, and the American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons.” Circulation 130, no. 19 (November 4, 2014): 1749–67. https://doi.org/10.1161/CIR.0000000000000095.Full Text Link to Item
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Kontos, Michael C., Stephen L. Rennyson, Anita Y. Chen, Karen P. Alexander, Eric D. Peterson, and Matthew T. Roe. “The association of myocardial infarction process of care measures and in-hospital mortality: a report from the NCDR®.” Am Heart J 168, no. 5 (November 2014): 766–75. https://doi.org/10.1016/j.ahj.2014.07.005.Full Text Link to Item
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Bangalore, Sripal, Harikrishna Makani, Martha Radford, Kamia Thakur, Bora Toklu, Stuart D. Katz, James J. DiNicolantonio, et al. “Clinical outcomes with β-blockers for myocardial infarction: a meta-analysis of randomized trials.” Am J Med 127, no. 10 (October 2014): 939–53. https://doi.org/10.1016/j.amjmed.2014.05.032.Full Text Link to Item
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Ohman, E Magnus, and Karen P. Alexander. “The challenges with chronic angina.” N Engl J Med 371, no. 12 (September 18, 2014): 1152–53. https://doi.org/10.1056/NEJMe1409369.Full Text Link to Item
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Hall, Hurst M., James A. de Lemos, Jonathan R. Enriquez, Darren K. McGuire, S Andrew Peng, Karen P. Alexander, Matthew T. Roe, Nihar Desai, Stephen D. Wiviott, and Sandeep R. Das. “Contemporary patterns of discharge aspirin dosing after acute myocardial infarction in the United States: results from the National Cardiovascular Data Registry (NCDR).” Circ Cardiovasc Qual Outcomes 7, no. 5 (September 2014): 701–7. https://doi.org/10.1161/CIRCOUTCOMES.113.000822.Full Text Link to Item
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Salisbury, Adam C., Kimberly J. Reid, Steven P. Marso, Amit P. Amin, Karen P. Alexander, Tracy Y. Wang, John A. Spertus, and Mikhail Kosiborod. “Blood transfusion during acute myocardial infarction: association with mortality and variability across hospitals.” J Am Coll Cardiol 64, no. 8 (August 26, 2014): 811–19. https://doi.org/10.1016/j.jacc.2014.05.040.Full Text Link to Item
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Bagai, Akshay, Yongfei Wang, Tracy Y. Wang, Jeptha P. Curtis, Hitinder S. Gurm, Binita Shah, Asim N. Cheema, et al. “In-hospital switching between clopidogrel and prasugrel among patients with acute myocardial infarction treated with percutaneous coronary intervention: insights into contemporary practice from the national cardiovascular data registry.” Circ Cardiovasc Interv 7, no. 4 (August 2014): 585–93. https://doi.org/10.1161/CIRCINTERVENTIONS.114.001555.Full Text Link to Item
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Lindman, Brian R., Karen P. Alexander, Patrick T. O’Gara, and Jonathan Afilalo. “Futility, benefit, and transcatheter aortic valve replacement.” Jacc Cardiovasc Interv 7, no. 7 (July 2014): 707–16. https://doi.org/10.1016/j.jcin.2014.01.167.Full Text Link to Item
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Beatty, Alexis L., Shuang Li, Laine Thomas, Ezra A. Amsterdam, Karen P. Alexander, and Mary A. Whooley. “Trends in referral to cardiac rehabilitation after myocardial infarction: data from the National Cardiovascular Data Registry 2007 to 2012.” J Am Coll Cardiol 63, no. 23 (June 17, 2014): 2582–83. https://doi.org/10.1016/j.jacc.2014.03.030.Full Text Link to Item
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Shen, Lan, Bimal R. Shah, Aro Nam, DaJuanicia Holmes, Karen P. Alexander, Deepak L. Bhatt, P Michael Ho, Eric D. Peterson, Ben He, and Matthew T. Roe. “Implications of prior myocardial infarction for patients presenting with an acute myocardial infarction.” Am Heart J 167, no. 6 (June 2014): 840–45. https://doi.org/10.1016/j.ahj.2014.03.009.Full Text Link to Item
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Wang, Tracy Y., David J. Magid, Henry H. Ting, Shuang Li, Karen P. Alexander, Matthew T. Roe, and Eric D. Peterson. “The quality of antiplatelet and anticoagulant medication administration among ST-segment elevation myocardial infarction patients transferred for primary percutaneous coronary intervention.” Am Heart J 167, no. 6 (June 2014): 833–39. https://doi.org/10.1016/j.ahj.2014.03.002.Full Text Link to Item
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O’Brien, Emily, Sumeet Subherwal, Matthew T. Roe, DaJuanicia N. Holmes, Laine Thomas, Karen P. Alexander, Tracy Y. Wang, and Eric D. Peterson. “Do patients treated at academic hospitals have better longitudinal outcomes after admission for non-ST-elevation myocardial infarction?” Am Heart J 167, no. 5 (May 2014): 762–69. https://doi.org/10.1016/j.ahj.2014.01.009.Full Text Link to Item
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Afilalo, Jonathan, Karen P. Alexander, Michael J. Mack, Mathew S. Maurer, Philip Green, Larry A. Allen, Jeffrey J. Popma, Luigi Ferrucci, and Daniel E. Forman. “Frailty assessment in the cardiovascular care of older adults.” J Am Coll Cardiol 63, no. 8 (March 4, 2014): 747–62. https://doi.org/10.1016/j.jacc.2013.09.070.Full Text Link to Item
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Waldo, Stephen W., Daniel A. Brenner, Shuang Li, Karen Alexander, and Peter Ganz. “Reperfusion times and in-hospital outcomes among patients with an isolated posterior myocardial infarction: insights from the National Cardiovascular Data Registry (NCDR).” Am Heart J 167, no. 3 (March 2014): 350–54. https://doi.org/10.1016/j.ahj.2013.11.011.Full Text Link to Item
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Xian, Ying, Anita Y. Chen, Laine Thomas, Matthew T. Roe, Sumeet Subherwal, Christopher P. Cannon, Charles V. Pollack, et al. “Sources of hospital-level variation in major bleeding among patients with non-st-segment elevation myocardial infarction: a report from the National Cardiovascular Data Registry (NCDR).” Circ Cardiovasc Qual Outcomes 7, no. 2 (March 2014): 236–43. https://doi.org/10.1161/CIRCOUTCOMES.113.000715.Full Text Link to Item
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Diepen, Sean van, Anita Y. Chen, Tracy Y. Wang, Karen P. Alexander, Justin A. Ezekowitz, Eric D. Peterson, and Matthew T. Roe. “Influence of heart failure symptoms and ejection fraction on short- and long-term outcomes for older patients with non-ST-segment elevation myocardial infarction.” Am Heart J 167, no. 2 (February 2014): 267-273.e1. https://doi.org/10.1016/j.ahj.2013.11.005.Full Text Link to Item
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Chin, Chee Tang, Tracy Y. Wang, Anita Y. Chen, Robin Mathews, Karen P. Alexander, Matthew T. Roe, and Eric D. Peterson. “Trends in outcomes among older patients with non-ST-segment elevation myocardial infarction.” Am Heart J 167, no. 1 (January 2014): 36-42.e1. https://doi.org/10.1016/j.ahj.2013.10.008.Full Text Link to Item
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O’Brien, Emily C., Emil L. Fosbol, S Andrew Peng, Karen P. Alexander, Matthew T. Roe, and Eric D. Peterson. “Association of body mass index and long-term outcomes in older patients with non-ST-segment-elevation myocardial infarction: results from the CRUSADE Registry.” Circ Cardiovasc Qual Outcomes 7, no. 1 (January 2014): 102–9. https://doi.org/10.1161/CIRCOUTCOMES.113.000421.Full Text Link to Item
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Rao, Krishnasree K., Jonathan R. Enriquez, James A. de Lemos, Karen P. Alexander, Anita Y. Chen, Darren K. McGuire, Gregg C. Fonarow, and Sandeep R. Das. “Use of aldosterone antagonists at discharge after myocardial infarction: results from the National Cardiovascular Data Registry Acute Coronary Treatment and Intervention Outcomes Network (ACTION) Registry-Get with the Guidelines (GWTG).” Am Heart J 166, no. 4 (October 2013): 709–15. https://doi.org/10.1016/j.ahj.2013.06.020.Full Text Link to Item
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Subherwal, Sumeet, E Magnus Ohman, Kenneth W. Mahaffey, Sunil V. Rao, John H. Alexander, Tracy Y. Wang, Karen P. Alexander, Vic Hasselblad, and Matthew T. Roe. “Incorporation of bleeding as an element of the composite end point in clinical trials of antithrombotic therapies in patients with non-ST-segment elevation acute coronary syndrome: validity, pitfalls, and future approaches.” Am Heart J 165, no. 5 (May 2013): 644-654.e1. https://doi.org/10.1016/j.ahj.2012.11.012.Full Text Link to Item
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Hanna, Elias B., Karen P. Alexander, Anita Y. Chen, Matthew T. Roe, Marjorie Funk, and Jorge F. Saucedo. “Characteristics and in-hospital outcomes of patients with non-ST-segment elevation myocardial infarction undergoing an invasive strategy according to hemoglobin levels.” Am J Cardiol 111, no. 8 (April 15, 2013): 1099–1103. https://doi.org/10.1016/j.amjcard.2012.12.041.Full Text Link to Item
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Hall, Hurst M., Jonathan R. Enriquez, James A. de Lemos, Nihar Desai, S Andrew Peng, Karen P. Alexander, Matthew T. Roe, Darren K. McGuire, Stephen D. Wiviott, and Sandeep R. Das. “Patterns of Discharge Aspirin Dosing in 213,344 US Patients after Acute Myocardial Infarction: Results from the NCDR.” Circulation 126, no. 21 (November 20, 2012).Link to Item
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Prvu Bettger, Janet, Karen P. Alexander, Rowena J. Dolor, DaiWai M. Olson, Amy S. Kendrick, Liz Wing, Remy R. Coeytaux, Carmelo Graffagnino, and Pamela W. Duncan. “Transitional care after hospitalization for acute stroke or myocardial infarction: a systematic review.” Ann Intern Med 157, no. 6 (September 18, 2012): 407–16. https://doi.org/10.7326/0003-4819-157-6-201209180-00004.Full Text Link to Item
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Holmes, David R., Michael J. Mack, Sanjay Kaul, Arvind Agnihotri, Karen P. Alexander, Steven R. Bailey, John H. Calhoon, et al. “2012 ACCF/AATS/SCAI/STS expert consensus document on transcatheter aortic valve replacement: developed in collabration with the American Heart Association, American Society of Echocardiography, European Association for Cardio-Thoracic Surgery, Heart Failure Society of America, Mended Hearts, Society of Cardiovascular Anesthesiologists, Society of Cardiovascular Computed Tomography, and Society for Cardiovascular Magnetic Resonance.” J Thorac Cardiovasc Surg 144, no. 3 (September 2012): e29–84. https://doi.org/10.1016/j.jtcvs.2012.03.001.Full Text Link to Item
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Lopes, Renato D., Li Li, Christopher B. Granger, Tracy Y. Wang, JoAnne M. Foody, Marjorie Funk, Eric D. Peterson, and Karen P. Alexander. “Atrial fibrillation and acute myocardial infarction: antithrombotic therapy and outcomes.” Am J Med 125, no. 9 (September 2012): 897–905. https://doi.org/10.1016/j.amjmed.2012.04.006.Full Text Link to Item
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Lopes, Renato D., Sumeet Subherwal, Dajuanicia N. Holmes, Laine Thomas, Tracy Y. Wang, Sunil V. Rao, Erik Magnus Ohman, Matthew T. Roe, Eric D. Peterson, and Karen P. Alexander. “The association of in-hospital major bleeding with short-, intermediate-, and long-term mortality among older patients with non-ST-segment elevation myocardial infarction.” Eur Heart J 33, no. 16 (August 2012): 2044–53. https://doi.org/10.1093/eurheartj/ehs012.Full Text Link to Item
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Subherwal, Sumeet, Deepak L. Bhatt, Shuang Li, Tracy Y. Wang, Laine Thomas, Karen P. Alexander, Manesh R. Patel, et al. “Polyvascular disease and long-term cardiovascular outcomes in older patients with non-ST-segment-elevation myocardial infarction.” Circ Cardiovasc Qual Outcomes 5, no. 4 (July 1, 2012): 541–49. https://doi.org/10.1161/CIRCOUTCOMES.111.964379.Full Text Link to Item
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Holmes, David R., Michael J. Mack, Sanjay Kaul, Arvind Agnihotri, Karen P. Alexander, Steven R. Bailey, John H. Calhoon, et al. “2012 ACCF/AATS/SCAI/STS expert consensus document on transcatheter aortic valve replacement: developed in collaboration with the American Heart Association, American Society of Echocardiography, European Association for Cardio-Thoracic Surgery, Heart Failure Society of America, Mended Hearts, Society of Cardiovascular Anesthesiologists, Society of Cardiovascular Computed Tomography, and Society for Cardiovascular Magnetic Resonance.” Catheter Cardiovasc Interv 79, no. 7 (June 1, 2012): 1023–82. https://doi.org/10.1002/ccd.24351.Full Text Link to Item
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Dodson, John A., Suzanne V. Arnold, Kimberly J. Reid, Thomas M. Gill, Michael W. Rich, Frederick A. Masoudi, John A. Spertus, Harlan M. Krumholz, and Karen P. Alexander. “Physical function and independence 1 year after myocardial infarction: observations from the Translational Research Investigating Underlying disparities in recovery from acute Myocardial infarction: Patients' Health status registry.” Am Heart J 163, no. 5 (May 2012): 790–96. https://doi.org/10.1016/j.ahj.2012.02.024.Full Text Link to Item
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Salisbury, Adam C., Amit P. Amin, Kimberly J. Reid, Tracy Y. Wang, Karen P. Alexander, Paul S. Chan, Frederick A. Masoudi, John A. Spertus, and Mikhail Kosiborod. “Red blood cell indices and development of hospital-acquired anemia during acute myocardial infarction.” Am J Cardiol 109, no. 8 (April 15, 2012): 1104–10. https://doi.org/10.1016/j.amjcard.2011.11.045.Full Text Link to Item
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Holmes, David R., Michael J. Mack, Sanjay Kaul, Arvind Agnihotri, Karen P. Alexander, Steven R. Bailey, John H. Calhoon, et al. “2012 ACCF/AATS/SCAI/STS expert consensus document on transcatheter aortic valve replacement: developed in collaboration with the American Heart Association, American Society of Echocardiography, European Association for Cardio-Thoracic Surgery, Heart Failure Society of America, Mended Hearts, Society of Cardiovascular Anesthesiologists, Society of Cardiovascular Computed Tomography, and Society for Cardiovascular Magnetic Resonance.” Ann Thorac Surg 93, no. 4 (April 2012): 1340–95. https://doi.org/10.1016/j.athoracsur.2012.01.084.Full Text Link to Item
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Subherwal, Sumeet, Eric D. Peterson, Anita Y. Chen, Matthew T. Roe, Jeffrey B. Washam, Brian F. Gage, Richard G. Bach, et al. “Admission international normalized ratio levels, early treatment strategies, and major bleeding risk among non-ST-segment-elevation myocardial infarction patients on home warfarin therapy: insights from the National Cardiovascular Data Registry.” Circulation 125, no. 11 (March 20, 2012): 1414–23. https://doi.org/10.1161/CIRCULATIONAHA.111.059188.Full Text Link to Item
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Brennan, J Matthew, Karen P. Alexander, Amelie Wallace, Audra B. Hodges, John C. Laschinger, Kent W. Jones, Sean O’Brien, Laura E. Webb, Rachel S. Dokholyan, and Eric D. Peterson. “Patterns of anticoagulation following bioprosthetic valve implantation: observations from ANSWER.” J Heart Valve Dis 21, no. 1 (January 2012): 78–87.Link to Item
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Bachuwar, Alok, Karen P. Alexander, Kimberly J. Reid, Mikhail Kosoborod, Tracy Y. Wang, John Spertus, and Richard G. Bach. “Bleeding After Discharge Following Hospitalization for Acute Myocardial Infarction.” Circulation 124, no. 21 (November 22, 2011).Link to Item
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Melloni, Chiara, Matthew T. Roe, Anita Y. Chen, Tracy Y. Wang, Stephen D. Wiviott, P Michael Ho, Eric D. Peterson, and Karen P. Alexander. “Use of early clopidogrel by reperfusion strategy among patients presenting with ST-segment elevation myocardial infarction.” Circ Cardiovasc Qual Outcomes 4, no. 6 (November 1, 2011): 603–9. https://doi.org/10.1161/CIRCOUTCOMES.111.961045.Full Text Link to Item
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Melloni, Chiara, Bimal R. Shah, Fang-Shu Ou, Matthew T. Roe, Sidney C. Smith, Charles V. Pollack, Magnus Ohman, W Brian Gibler, Eric D. Peterson, and Karen P. Alexander. “Lipid-lowering intensification and low-density lipoprotein cholesterol achievement from hospital admission to 1-year follow-up after an acute coronary syndrome event: results from the Medications ApplIed aNd SusTAINed Over Time (MAINTAIN) registry.” Am Heart J 160, no. 6 (December 2010): 1121-1129.e1. https://doi.org/10.1016/j.ahj.2010.09.008.Full Text Link to Item
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Brennan, J Matthew, Karen P. Alexander, Audra B. Hodges, John C. Laschinger, Kent W. Jones, Sean O’Brien, Laura E. Webb, Rachel Dokholyan, and Eric D. Peterson. “Patterns of Anticoagulation following Bioprosthetic Valve Implantation: Observations from ANSWER.” Circulation 122, no. 21 (November 23, 2010).Link to Item
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Dodson, John A., Karen P. Alexander, Suzanne V. Arnold, Kimberly J. Reid, Michael W. Rich, Frederick A. Masoudi, John A. Spertus, and Harlan M. Krumholz. “Predictors of Functional Decline One Year Post-Myocardial Infarction in Older Adults.” Circulation 122, no. 21 (November 23, 2010).Link to Item
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Hanna, Elias B., Karen P. Alexander, Anita Y. Chen, Matthew T. Roe, Marjorie Funk, P. M. Ho, and Jorge F. Saucedo. “In-hospital Outcomes of Anemic Patients Presenting with Non-ST Elevation Myocardial Infarction and Undergoing an Invasive Strategy.” Circulation 122, no. 21 (November 23, 2010).Link to Item
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Lopes, Renato D., Li Li, Christopher B. Granger, Tracy Y. Wang, JoAnne M. Foody, Marjorie Funk, Eric D. Peterson, and Karen P. Alexander. “Discharge Warfarin is Underused in High Risk Atrial Fibrillation Patients With Myocardial Infarction.” Circulation 122, no. 21 (November 23, 2010).Link to Item
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Subherwal, Sumeet, Eric D. Peterson, Anita Y. Chen, Richard G. Bach, Brian F. Gage, Deepak L. Bhatt, Stephen D. Wiviott, et al. “Is Bleeding Risk Augmented With Acute Therapies Across Increasing INR Levels Among NSTEMI Patients on Home Warfarin Therapy?” Circulation 122, no. 21 (November 23, 2010).Link to Item
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Forman, Daniel E., Anita Y. Chen, Stephen D. Wiviott, Tracy Y. Wang, David J. Magid, and Karen P. Alexander. “Comparison of outcomes in patients aged <75, 75 to 84, and ≥ 85 years with ST-elevation myocardial infarction (from the ACTION Registry-GWTG).” Am J Cardiol 106, no. 10 (November 15, 2010): 1382–88. https://doi.org/10.1016/j.amjcard.2010.07.008.Full Text Link to Item
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Afilalo, Jonathan, Mark J. Eisenberg, Jean-François Morin, Howard Bergman, Johanne Monette, Nicolas Noiseux, Louis P. Perrault, et al. “Gait speed as an incremental predictor of mortality and major morbidity in elderly patients undergoing cardiac surgery.” J Am Coll Cardiol 56, no. 20 (November 9, 2010): 1668–76. https://doi.org/10.1016/j.jacc.2010.06.039.Full Text Link to Item
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Kadakia, Mitul B., Nihar R. Desai, Karen P. Alexander, Anita Y. Chen, Joanne M. Foody, Christopher P. Cannon, Stephen D. Wiviott, Benjamin M. Scirica, and Benjamin M. National Cardiovascular Data Registry. “Use of anticoagulant agents and risk of bleeding among patients admitted with myocardial infarction: a report from the NCDR ACTION Registry--GWTG (National Cardiovascular Data Registry Acute Coronary Treatment and Intervention Outcomes Network Registry--Get With the Guidelines).” Jacc Cardiovasc Interv 3, no. 11 (November 2010): 1166–77. https://doi.org/10.1016/j.jcin.2010.08.015.Full Text Link to Item
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Lansky, Alexandra J., Kenji Goto, Ecaterina Cristea, Martin Fahy, Helen Parise, Frederick Feit, E Magnus Ohman, et al. “Clinical and angiographic predictors of short- and long-term ischemic events in acute coronary syndromes: results from the Acute Catheterization and Urgent Intervention Triage strategY (ACUITY) trial.” Circ Cardiovasc Interv 3, no. 4 (August 2010): 308–16. https://doi.org/10.1161/CIRCINTERVENTIONS.109.887604.Full Text Link to Item
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Salisbury, Adam C., Karen P. Alexander, Kimberly J. Reid, Frederick A. Masoudi, Saif S. Rathore, Tracy Y. Wang, Richard G. Bach, Steven P. Marso, John A. Spertus, and Mikhail Kosiborod. “Incidence, correlates, and outcomes of acute, hospital-acquired anemia in patients with acute myocardial infarction.” Circ Cardiovasc Qual Outcomes 3, no. 4 (July 2010): 337–46. https://doi.org/10.1161/CIRCOUTCOMES.110.957050.Full Text Link to Item
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Lopes, Renato D., Eric D. Peterson, Anita Y. Chen, Matthew T. Roe, Tracy Y. Wang, E Magnus Ohman, David J. Magid, et al. “Antithrombotic strategy in non-ST-segment elevation myocardial infarction patients undergoing percutaneous coronary intervention: insights from the ACTION (Acute Coronary Treatment and Intervention Outcomes Network) Registry.” Jacc Cardiovasc Interv 3, no. 6 (June 2010): 669–77. https://doi.org/10.1016/j.jcin.2010.03.015.Full Text Link to Item
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Alexander, Karen P., and Eric D. Peterson. “Minimizing the risks of anticoagulants and platelet inhibitors.” Circulation 121, no. 17 (May 4, 2010): 1960–70. https://doi.org/10.1161/CIRCULATIONAHA.109.853135.Full Text Link to Item
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Gharacholou, Shahyar Michael, Karen P. Alexander, Anita Y. Chen, Tracy Y. Wang, Chiara Melloni, W Brian Gibler, Charles V. Pollack, E Magnus Ohman, Eric D. Peterson, and Matthew T. Roe. “Implications and reasons for the lack of use of reperfusion therapy in patients with ST-segment elevation myocardial infarction: findings from the CRUSADE initiative.” Am Heart J 159, no. 5 (May 2010): 757–63. https://doi.org/10.1016/j.ahj.2010.02.009.Full Text Link to Item
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Smolderen, Kim G., John A. Spertus, Brahmajee K. Nallamothu, Harlan M. Krumholz, Fengming Tang, Joseph S. Ross, Henry H. Ting, Karen P. Alexander, Saif S. Rathore, and Paul S. Chan. “Health care insurance, financial concerns in accessing care, and delays to hospital presentation in acute myocardial infarction.” Jama 303, no. 14 (April 14, 2010): 1392–1400. https://doi.org/10.1001/jama.2010.409.Full Text Link to Item
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Michaels, Andrew D., Sarah A. Spinler, Barbara Leeper, E Magnus Ohman, Karen P. Alexander, L Kristin Newby, Hakan Ay, et al. “Medication errors in acute cardiovascular and stroke patients: a scientific statement from the American Heart Association.” Circulation 121, no. 14 (April 13, 2010): 1664–82. https://doi.org/10.1161/CIR.0b013e3181d4b43e.Full Text Link to Item
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Allen LaPointe, Nancy M., Fang-Shu Ou, Sara B. Calvert, Chiara Melloni, Judith A. Stafford, Tina Harding, Karen P. Alexander, and Eric D. Peterson. “Changes in beliefs about medications during long-term care for ischemic heart disease.” Am Heart J 159, no. 4 (April 2010): 561–69. https://doi.org/10.1016/j.ahj.2009.12.025.Full Text Link to Item
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Goto, Kenji, Alexandra J. Lansky, Martin Fahy, Ecatarina Cristea, Frederick Feit, E Magnus Ohman, Harvey D. White, et al. “Predictors of outcomes in medically treated patients with acute coronary syndromes after angiographic triage: an Acute Catheterization And Urgent Intervention Triage Strategy (ACUITY) substudy.” Circulation 121, no. 7 (February 23, 2010): 853–62. https://doi.org/10.1161/CIRCULATIONAHA.109.877944.Full Text Link to Item
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Fox, Caroline S., Paul Muntner, Anita Y. Chen, Karen P. Alexander, Matthew T. Roe, Christopher P. Cannon, Jorge F. Saucedo, Michael C. Kontos, Stephen D. Wiviott, and Stephen D. Acute Coronary Treatment and Intervention Outcomes Network registry. “Use of evidence-based therapies in short-term outcomes of ST-segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction in patients with chronic kidney disease: a report from the National Cardiovascular Data Acute Coronary Treatment and Intervention Outcomes Network registry.” Circulation 121, no. 3 (January 26, 2010): 357–65. https://doi.org/10.1161/CIRCULATIONAHA.109.865352.Full Text Link to Item
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Tsai, Thomas T., Thomas M. Maddox, Matthew T. Roe, David Dai, Karen P. Alexander, P Michael Ho, John C. Messenger, et al. “Contraindicated medication use in dialysis patients undergoing percutaneous coronary intervention.” Jama 302, no. 22 (December 9, 2009): 2458–64. https://doi.org/10.1001/jama.2009.1800.Full Text Link to Item
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Gharacholou, S. M., and K. P. Alexander. “Evolving role of revascularization in older adults with acute coronary syndrome.” Current Cardiovascular Risk Reports 3, no. 5 (December 1, 2009): 355–65. https://doi.org/10.1007/s12170-009-0052-5.Full Text
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Cavender, Matthew A., Karen P. Alexander, Samuel Broderick, Linda K. Shaw, Charles B. McCants, Judith Kempf, and E Magnus Ohman. “Long-term morbidity and mortality among medically managed patients with angina and multivessel coronary artery disease.” Am Heart J 158, no. 6 (December 2009): 933–40. https://doi.org/10.1016/j.ahj.2009.10.013.Full Text Link to Item
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Ali, Robin C., Chiara Melloni, Fang-Shu Ou, Kenneth Schmader, E Magnus Ohman, Matthew T. Roe, Eric D. Peterson, and Karen P. Alexander. “Age and persistent use of cardiovascular medication after acute coronary syndrome: results from medication applied and sustained over time.” J Am Geriatr Soc 57, no. 11 (November 2009): 1990–96. https://doi.org/10.1111/j.1532-5415.2009.02483.x.Full Text Link to Item
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Lopes, Renato D., and Karen P. Alexander. “Antiplatelet therapy in older adults with non-ST-segment elevation acute coronary syndrome: considering risks and benefits.” Am J Cardiol 104, no. 5 Suppl (September 7, 2009): 16C-21C. https://doi.org/10.1016/j.amjcard.2009.06.021.Full Text Link to Item
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Melloni, Chiara, Karen P. Alexander, Fang-Shu Ou, Nancy M Allen LaPointe, Matthew T. Roe, L Kristin Newby, Khaula Baloch, P Michael Ho, John S. Rumsfeld, and Eric D. Peterson. “Predictors of early discontinuation of evidence-based medicine after acute coronary syndrome.” Am J Cardiol 104, no. 2 (July 15, 2009): 175–81. https://doi.org/10.1016/j.amjcard.2009.03.013.Full Text Link to Item
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Joffe, A. “Too much of a good thing--air, that is.” Anaesth Intensive Care 37, no. 4 (July 2009): 664.Link to Item
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Armstrong, Paul W., and Karen P. Alexander. “Nebivolol in older adults with heart failure: reduced rates for seniors?” J Am Coll Cardiol 53, no. 23 (June 9, 2009): 2159–61. https://doi.org/10.1016/j.jacc.2009.03.019.Full Text Link to Item
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Spinler, Sarah A., Fang-Shu Ou, Matthew T. Roe, W Brian Gibler, E Magnus Ohman, Charles V. Pollack, Karen P. Alexander, and Eric D. Peterson. “Weight-based dosing of enoxaparin in obese patients with non-ST-segment elevation acute coronary syndromes: results from the CRUSADE initiative.” Pharmacotherapy 29, no. 6 (June 2009): 631–38. https://doi.org/10.1592/phco.29.6.631.Full Text Link to Item
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Afilalo, Jonathan, Sathya Karunananthan, Mark J. Eisenberg, Karen P. Alexander, and Howard Bergman. “Role of frailty in patients with cardiovascular disease.” Am J Cardiol 103, no. 11 (June 1, 2009): 1616–21. https://doi.org/10.1016/j.amjcard.2009.01.375.Full Text Link to Item
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Lansky, Alexandra J., Roxana Mehran, Ecatarina Cristea, Helen Parise, Frederick Feit, E Magnus Ohman, Harvey D. White, et al. “Impact of gender and antithrombin strategy on early and late clinical outcomes in patients with non-ST-elevation acute coronary syndromes (from the ACUITY trial).” Am J Cardiol 103, no. 9 (May 1, 2009): 1196–1203. https://doi.org/10.1016/j.amjcard.2009.01.030.Full Text Link to Item
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Subherwal, Sumeet, Richard G. Bach, Anita Y. Chen, Brian F. Gage, Sunil V. Rao, L Kristin Newby, Tracy Y. Wang, et al. “Baseline risk of major bleeding in non-ST-segment-elevation myocardial infarction: the CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA Guidelines) Bleeding Score.” Circulation 119, no. 14 (April 14, 2009): 1873–82. https://doi.org/10.1161/CIRCULATIONAHA.108.828541.Full Text Link to Item
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Melloni, C., E. D. Peterson, A. Y. Chen, L. A. Szczech, L. K. Newby, R. A. Harrington, W. B. Gibler, et al. “Cockcroft-Gault Versus Modification of Diet in Renal Disease: Importance of Glomerular Filtration Rate Formula for Classification of Chronic Kidney Disease in Patients With Non-ST-Segment Elevation Acute Coronary Syndromes Editorial Comment.” Journal of Urology 181, no. 4 (April 1, 2009): 1813–14.Link to Item
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Lopes, Renato D., Karen P. Alexander, Steven V. Manoukian, Michel E. Bertrand, Frederick Feit, Harvey D. White, Charles V. Pollack, et al. “Advanced age, antithrombotic strategy, and bleeding in non-ST-segment elevation acute coronary syndromes: results from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial.” J Am Coll Cardiol 53, no. 12 (March 24, 2009): 1021–30. https://doi.org/10.1016/j.jacc.2008.12.021.Full Text Link to Item
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Alexander, Karen P., Anita Y. Chen, Matthew T. Roe, Tracy Y. Wang, Erik M. Ohman, David J. Magid, Michael P. Ho, Stephen D. Wiviott, Benjamin M. Scirica, and Eric D. Peterson. “Antithrombotic Strategy During Percutaneous Coronary Iintervention in NSTEMI: Update From ACTION Registry-GWTG.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A398–A398.Link to Item
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Forman, Daniel E., Anita Y. Chen, Stephen D. Wiviott, Tracy Y. Wang, David J. Magid, and Karen P. Alexander. “ST-Elevation Myocardial Infarction Care and Outcomes for the Oldest-Old.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A325–A325.Link to Item
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Gharacholou, Shahyar M., Anita Y. Chen, Karen P. Alexander, Jorge F. Saucedo, James de Lemos, Michael C. Kontos, Eric D. Peterson, John Rumsfeld, and Matthew T. Roe. “Limitations of Using Cardiac Catheterization Rates as a Quality Measure for Non ST-Segment Elevation Myocardial Infarction.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A370–A370.Link to Item
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Kadakia, Mitul B., Nihar R. Desai, Karen P. Alexander, Anita Y. Chen, JoAnne M. Foody, Christopher P. Cannon, Stephen D. Wiviott, and Benjamin M. Scirica. “Utilization of Antithrombotic Agents Among Patients Admitted With Myocardial Infarction in the ACTION Registry-GWTG.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A324–25.Link to Item
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Subherwal, Sumeet, Anita Y. Chen, Richard G. Bach, Matthew T. Roe, Eric D. Peterson, and Karen P. Alexander. “Risk of GUSTO Moderate or Severe Bleeding identified by the CRUSADE Bleeding Model.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A384–A384.Link to Item
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Alexander, Karen P., Michael A. Blazing, Robert S. Rosenson, Elisabeth Hazard, Wilbert S. Aronow, Sidney C. Smith, and E Magnus Ohman. “Management of hyperlipidemia in older adults.” J Cardiovasc Pharmacol Ther 14, no. 1 (March 2009): 49–58. https://doi.org/10.1177/1074248408328927.Full Text Link to Item
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Arnold, Suzanne V., Karen P. Alexander, Frederick A. Masoudi, P Michael Ho, Lan Xiao, and John A. Spertus. “The effect of age on functional and mortality outcomes after acute myocardial infarction.” J Am Geriatr Soc 57, no. 2 (February 2009): 209–17. https://doi.org/10.1111/j.1532-5415.2008.02106.x.Full Text Link to Item
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Cohen, Marc, Karen P. Alexander, and Sunil V. Rao. “Bleeding after antithrombotic therapy in patients with acute ischemic heart disease: is it the drugs or how we use them?” J Thromb Thrombolysis 26, no. 3 (December 2008): 175–82. https://doi.org/10.1007/s11239-007-0182-x.Full Text Link to Item
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Wang, Tracy Y., Lan Xiao, Karen P. Alexander, Sunil V. Rao, Mikhail N. Kosiborod, John S. Rumsfeld, John A. Spertus, and Eric D. Peterson. “Antiplatelet therapy use after discharge among acute myocardial infarction patients with in-hospital bleeding.” Circulation 118, no. 21 (November 18, 2008): 2139–45. https://doi.org/10.1161/CIRCULATIONAHA.108.787143.Full Text Link to Item
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Alexander, Karen P., Patricia A. Cowper, Judith A. Kempf, Barbara L. Lytle, and Eric D. Peterson. “Profile of chronic and recurrent angina pectoris in a referral population.” Am J Cardiol 102, no. 10 (November 15, 2008): 1301–6. https://doi.org/10.1016/j.amjcard.2008.07.006.Full Text Link to Item
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Patel, Uptal D., Joshua Grab, Mikhail Kosiborod, Barbara Lytle, Eric D. Peterson, and Karen P. Alexander. “Impact of anemia on physical function and survival among patients with coronary artery disease.” Clin Cardiol 31, no. 11 (November 2008): 546–50. https://doi.org/10.1002/clc.20283.Full Text Link to Item
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Cavender, Matthew A., Karen P. Alexander, Samuel Broderick, Linda K. Shaw, Judith Kempf, and E Magnus Ohman. “Long-Term Morbidity and Mortality among Patients with Angina and Multivessel Coronary Artery Disease in the Duke Cardiovascular Databank.” Circulation 118, no. 18 (October 28, 2008): S853–S853.Link to Item
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Fox, Caroline S., Paul Muntner, Anita Y. Chen, Karen P. Alexander, Matthew T. Roe, Jorge F. Saucedo, and Stephen D. Wiviott. “Short-Term Outcomes of STEMI and NSTEMI in Patients with Chronic Kidney Disease: A Report from the National Cardiovascular Data ACTION Registry.” Circulation 118, no. 18 (October 28, 2008): S966–S966.Link to Item
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Reeves, Gordon R., Tracy Y. Wang, Kimberly J. Reid, Karen P. Alexander, Carole Decker, Homaa Ahmad, John A. Spertus, and Eric D. Peterson. “Dissociation between hospital performance of the smoking cessation counseling quality metric and cessation outcomes after myocardial infarction.” Arch Intern Med 168, no. 19 (October 27, 2008): 2111–17. https://doi.org/10.1001/archinte.168.19.2111.Full Text Link to Item
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Roe, Matthew T., Fang-Shu Ou, Karen P. Alexander, Laura Kristin Newby, Joanne M. Foody, W Brian Gibler, William E. Boden, Erik Magnus Ohman, Sidney C. Smith, and Eric D. Peterson. “Patterns and prognostic implications of low high-density lipoprotein levels in patients with non-ST-segment elevation acute coronary syndromes.” Eur Heart J 29, no. 20 (October 2008): 2480–88. https://doi.org/10.1093/eurheartj/ehn364.Full Text Link to Item
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Singh, Mandeep, Karen Alexander, Veronique L. Roger, Charanjit S. Rihal, Heather E. Whitson, Amir Lerman, Arschad Jahangir, and K Sreekumaran Nair. “Frailty and its potential relevance to cardiovascular care.” Mayo Clin Proc 83, no. 10 (October 2008): 1146–53. https://doi.org/10.4065/83.10.1146.Full Text Link to Item
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Wang, Tracy Y., Anita Y. Chen, Karen P. Alexander, E Magnus Ohman, W Brian Gibler, Eric D. Peterson, and Matthew T. Roe. “Excess heparin dosing among fibrinolytic-treated patients with ST-segment elevation myocardial infarction.” Am J Med 121, no. 9 (September 2008): 805–10. https://doi.org/10.1016/j.amjmed.2008.04.023.Full Text Link to Item
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Dunlay, Shannon M., Karen P. Alexander, Chiara Melloni, Jennifer L. Kraschnewski, Li Liang, W Brian Gibler, Matthew T. Roe, E Magnus Ohman, and Eric D. Peterson. “Medical records and quality of care in acute coronary syndromes: results from CRUSADE.” Arch Intern Med 168, no. 15 (August 11, 2008): 1692–98. https://doi.org/10.1001/archinte.168.15.1692.Full Text Link to Item
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Lopes, Renato D., Karen P. Alexander, Gretchen Marcucci, Harvey D. White, Sarah Spinler, Jacques Col, Philip E. Aylward, Robert M. Califf, and Kenneth W. Mahaffey. “Outcomes in elderly patients with acute coronary syndromes randomized to enoxaparin vs. unfractionated heparin: results from the SYNERGY trial.” Eur Heart J 29, no. 15 (August 2008): 1827–33. https://doi.org/10.1093/eurheartj/ehn236.Full Text Link to Item
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Melloni, Chiara, Karen P. Alexander, Anita Y. Chen, L Kristin Newby, Matthew T. Roe, Nancy M. Allen LaPointe, Charles V. Pollack, et al. “Unfractionated heparin dosing and risk of major bleeding in non-ST-segment elevation acute coronary syndromes.” Am Heart J 156, no. 2 (August 2008): 209–15. https://doi.org/10.1016/j.ahj.2008.03.023.Full Text Link to Item
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Alexander, Karen P., Anita Y. Chen, Tracy Y. Wang, Sunil V. Rao, L Kristin Newby, Nancy M Allen LaPointe, E Magnus Ohman, et al. “Transfusion practice and outcomes in non-ST-segment elevation acute coronary syndromes.” Am Heart J 155, no. 6 (June 2008): 1047–53. https://doi.org/10.1016/j.ahj.2008.01.009.Full Text Link to Item
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Ho, P Michael, Marvin H. Eng, John S. Rumsfeld, John A. Spertus, Pamela N. Peterson, Philip G. Jones, Eric D. Peterson, et al. “The influence of age on health status outcomes after acute myocardial infarction.” Am Heart J 155, no. 5 (May 2008): 855–61. https://doi.org/10.1016/j.ahj.2007.11.032.Full Text Link to Item
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Melloni, Chiara, Eric D. Peterson, Anita Y. Chen, Lynda A. Szczech, L Kristin Newby, Robert A. Harrington, W Brian Gibler, et al. “Cockcroft-Gault versus modification of diet in renal disease: importance of glomerular filtration rate formula for classification of chronic kidney disease in patients with non-ST-segment elevation acute coronary syndromes.” J Am Coll Cardiol 51, no. 10 (March 11, 2008): 991–96. https://doi.org/10.1016/j.jacc.2007.11.045.Full Text Link to Item
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Melloni, Chiara, Karen P. Alexander, Sarah Milford-Beland, L Kristin Newby, Lynda A. Szczech, Charles V. Pollack, J Douglas Kirk, et al. “Prognostic value of troponins in patients with non-ST-segment elevation acute coronary syndromes and chronic kidney disease.” Clin Cardiol 31, no. 3 (March 2008): 125–29. https://doi.org/10.1002/clc.20210.Full Text Link to Item
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Dove, James T., Susan J. Zieman, Karen Alexander, and Andrew Miller. “President's page: Cardiovascular care in older adults: the ACC and SGC partnership builds new curriculum.” J Am Coll Cardiol 51, no. 6 (February 12, 2008): 672–73. https://doi.org/10.1016/j.jacc.2008.01.002.Full Text Link to Item
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Melloni, Chiara, Karen P. Alexander, Anita Y. Chen, Matthew T. Roe, L Kristin Newby, Magnus Ohman, W Brian Gibler, Sidney C. Smith, Charles V. Pollak, and Eric D. Peterson. “Unfractionated heparin dosing and major bleeding in non-ST-segment elevation acute coronary syndromes.” Circulation 116, no. 16 (October 16, 2007): 383–383.Link to Item
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Wang, Tracy Y., Anita Y. Chen, Matthew T. Roe, Karen P. Alexander, L Kristin Newby, Sidney C. Smith, Sripal Bangalore, W Brian Gibler, E Magnus Ohman, and Eric D. Peterson. “Comparison of baseline characteristics, treatment patterns, and in-hospital outcomes of Asian versus non-Asian white Americans with non-ST-segment elevation acute coronary syndromes from the CRUSADE quality improvement initiative.” Am J Cardiol 100, no. 3 (August 1, 2007): 391–96. https://doi.org/10.1016/j.amjcard.2007.03.035.Full Text Link to Item
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Wong, Cheuk-Kit, L Kristin Newby, Manju V. Bhapker, Phil E. Aylward, Matthias Pfisterer, Karen P. Alexander, Paul W. Armstrong, et al. “Use of evidence-based medicine for acute coronary syndromes in the elderly and very elderly: insights from the Sibrafiban vs aspirin to Yield Maximum Protection from ischemic Heart events postacute cOroNary sYndromes trials.” Am Heart J 154, no. 2 (August 2007): 313–21. https://doi.org/10.1016/j.ahj.2007.04.031.Full Text Link to Item
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LaPointe, Nancy M Allen, Anita Y. Chen, Karen P. Alexander, Matthew T. Roe, Charles V. Pollack, Barbara L. Lytle, Magnus E. Ohman, Brian W. Gibler, and Eric D. Peterson. “Enoxaparin dosing and associated risk of in-hospital bleeding and death in patients with non ST-segment elevation acute coronary syndromes.” Arch Intern Med 167, no. 14 (July 23, 2007): 1539–44. https://doi.org/10.1001/archinte.167.14.1539.Full Text Link to Item
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Purser, J. L., G. G. Fillenbaum, and K. P. Alexander. “Response to Dr. Denkinger et al. [12].” Journal of the American Geriatrics Society 55, no. 6 (June 1, 2007): 968–69. https://doi.org/10.1111/j.1532-5415.2007.01193.x.Full Text
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Kraschnewski, Jennifer L., Li Liang, Shannon M. Dunlay, Chiara Melloni, Deborah B. Diercks, W Brian Gibler, Matthew T. Roe, E Magnus Ohman, Eric D. Peterson, and Karen P. Alexander. “Age, presentation, and emergency department diagnosis of acute coronary syndromes: Results from CRUSADE.” Circulation 115, no. 21 (May 29, 2007): E584–E584.Link to Item
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Wang, Tracy Y., Lan Xiao, Karen P. Alexander, Mikhail N. Kosiborod, John S. Rumsfeld, John A. Spertus, and Eric D. Peterson. “Trends in antiplatelet therapy use following discharge among acute myocardial infarction patients with in-hospital bleeding.” Circulation 115, no. 21 (May 29, 2007): E575–E575.Link to Item
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Alexander, Karen P., L Kristin Newby, Christopher P. Cannon, Paul W. Armstrong, W Brian Gibler, Michael W. Rich, Frans Van de Werf, et al. “Acute coronary care in the elderly, part I: Non-ST-segment-elevation acute coronary syndromes: a scientific statement for healthcare professionals from the American Heart Association Council on Clinical Cardiology: in collaboration with the Society of Geriatric Cardiology.” Circulation 115, no. 19 (May 15, 2007): 2549–69. https://doi.org/10.1161/CIRCULATIONAHA.107.182615.Full Text Link to Item
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Alexander, Karen P., L Kristin Newby, Paul W. Armstrong, Christopher P. Cannon, W Brian Gibler, Michael W. Rich, Frans Van de Werf, et al. “Acute coronary care in the elderly, part II: ST-segment-elevation myocardial infarction: a scientific statement for healthcare professionals from the American Heart Association Council on Clinical Cardiology: in collaboration with the Society of Geriatric Cardiology.” Circulation 115, no. 19 (May 15, 2007): 2570–89. https://doi.org/10.1161/CIRCULATIONAHA.107.182616.Full Text Link to Item
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Skolnick, Adam H., Karen P. Alexander, Anita Y. Chen, Matthew T. Roe, Charles V. Pollack, E Magnus Ohman, John S. Rumsfeld, W Brian Gibler, Eric D. Peterson, and David J. Cohen. “Characteristics, management, and outcomes of 5,557 patients age > or =90 years with acute coronary syndromes: results from the CRUSADE Initiative.” J Am Coll Cardiol 49, no. 17 (May 1, 2007): 1790–97. https://doi.org/10.1016/j.jacc.2007.01.066.Full Text Link to Item
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Frazier, Camille G., Karen P. Alexander, L Kristin Newby, Susan Anderson, Erik Iverson, Milton Packer, Jay Cohn, Sidney Goldstein, and Pamela S. Douglas. “Associations of gender and etiology with outcomes in heart failure with systolic dysfunction: a pooled analysis of 5 randomized control trials.” J Am Coll Cardiol 49, no. 13 (April 3, 2007): 1450–58. https://doi.org/10.1016/j.jacc.2006.11.041.Full Text Link to Item
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Ali, Robin, and Karen P. Alexander. “Statins for the primary prevention of cardiovascular events in older adults: a review of the evidence.” Am J Geriatr Pharmacother 5, no. 1 (March 2007): 52–63. https://doi.org/10.1016/j.amjopharm.2007.03.008.Full Text Link to Item
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Purser, Jama L., Maragatha N. Kuchibhatla, Gerda G. Fillenbaum, Tina Harding, Eric D. Peterson, and Karen P. Alexander. “Identifying frailty in hospitalized older adults with significant coronary artery disease.” J Am Geriatr Soc 54, no. 11 (November 2006): 1674–81. https://doi.org/10.1111/j.1532-5415.2006.00914.x.Full Text Link to Item
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Alexander, Karen P., Anita Y. Chen, L Kristin Newby, Nancy M Allen LaPointe, E Magnus Ohman, Matthew T. Roe, William E. Boden, and Eric D. Peterson. “Blood transfusion and mortality among patients with non-ST-segment elevation acute coronary syndromes: Results from CRUSADE.” Circulation 114, no. 18 (October 31, 2006): 701–701.Link to Item
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Mellori, Chiara, Eric D. Peterson, Anita Y. Chen, Lynda A. Szczech, L Kristin Newby, Robert A. Harrington, W Brian Gibler, et al. “Importance of glomerular filtration rate formula for determining chronic kidney disease and clinical care in patients with acute coronary syndromes.” Circulation 114, no. 18 (October 31, 2006): 406–406.Link to Item
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Frazier, Camille G., Karen P. Alexander, L Kristin Newby, Milton Packer, Jay Cohn, Sidney Goldstein, Ake Hjalmarson, Susan Anderson, Erik Iverson, and Pamela S. Douglas. “Sex differences in heart failure with systolic dysfunction: A pooled analysis of five randomized control trials.” Circulation 114, no. 18 (October 31, 2006): 573–573.Link to Item
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Alexander, Karen P., Anita Y. Chen, L Kristin Newby, Janice B. Schwartz, Rita F. Redberg, Judith S. Hochman, Matthew T. Roe, et al. “Sex differences in major bleeding with glycoprotein IIb/IIIa inhibitors: results from the CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA guidelines) initiative.” Circulation 114, no. 13 (September 26, 2006): 1380–87. https://doi.org/10.1161/CIRCULATIONAHA.106.620815.Full Text Link to Item
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Kraschnewski, J. L., K. P. Alexander, and E. D. Peterson. “Coronary artery disease in later life.” Generations 30, no. 3 (September 1, 2006): 17–23.
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Alexander, Karen P., Laura Kristin Newby, Manju V. Bhapkar, Harvey D. White, Judith S. Hochman, Matthias E. Pfisterer, David J. Moliterno, et al. “International variation in invasive care of the elderly with acute coronary syndromes.” Eur Heart J 27, no. 13 (July 2006): 1558–64. https://doi.org/10.1093/eurheartj/ehl067.Full Text Link to Item
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Gharacholou, S Michael, and Karen P. Alexander. “Issues with care in the elderly patient presenting with acute ischemia.” Curr Heart Fail Rep 3, no. 2 (June 2006): 51–56. https://doi.org/10.1007/s11897-006-0002-1.Full Text Link to Item
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Alexander, K. P., and E. D. Peterson. “In reply [6].” Jama 295, no. 16 (April 26, 2006): 1897. https://doi.org/10.1001/jama.295.16.1897-b.Full Text
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Alexander, Karen P., and Eric D. Peterson. “Treatment of non-ST-elevation acute coronary syndrome in the elderly: current practice and future opportunities.” Am J Geriatr Cardiol 15, no. 1 (2006): 42–49. https://doi.org/10.1111/j.1076-7460.2006.04642.x.Full Text Link to Item
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Kulkarni, Sonali P., Karen P. Alexander, Barbara Lytle, Gerardo Heiss, and Eric D. Peterson. “Long-term adherence with cardiovascular drug regimens.” Am Heart J 151, no. 1 (January 2006): 185–91. https://doi.org/10.1016/j.ahj.2005.02.038.Full Text Link to Item
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Swaminathan, Rajesh V., and Karen P. Alexander. “Pulse pressure and vascular risk in the elderly: associations and clinical implications.” Am J Geriatr Cardiol 15, no. 4 (2006): 226–32. https://doi.org/10.1111/j.1076-7460.2006.04774.x.Full Text Link to Item
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Alexander, Karen P., Anita Y. Chen, Matthew T. Roe, L Kristin Newby, C Michael Gibson, Nancy M. Allen-LaPointe, Charles Pollack, et al. “Excess dosing of antiplatelet and antithrombin agents in the treatment of non-ST-segment elevation acute coronary syndromes.” Jama 294, no. 24 (December 28, 2005): 3108–16. https://doi.org/10.1001/jama.294.24.3108.Full Text Link to Item
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Yang, Xin, Karen P. Alexander, Anita Y. Chen, Matthew T. Roe, Ralph G. Brindis, Sunil V. Rao, W Brian Gibler, E Magnus Ohman, Eric D. Peterson, and Eric D. CRUSADE Investigators. “The implications of blood transfusions for patients with non-ST-segment elevation acute coronary syndromes: results from the CRUSADE National Quality Improvement Initiative.” J Am Coll Cardiol 46, no. 8 (October 18, 2005): 1490–95. https://doi.org/10.1016/j.jacc.2005.06.072.Full Text Link to Item
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Alexander, Karen P., Matthew T. Roe, Anita Y. Chen, Barbara L. Lytle, Charles V. Pollack, Joanne M. Foody, William E. Boden, et al. “Evolution in cardiovascular care for elderly patients with non-ST-segment elevation acute coronary syndromes: results from the CRUSADE National Quality Improvement Initiative.” J Am Coll Cardiol 46, no. 8 (October 18, 2005): 1479–87. https://doi.org/10.1016/j.jacc.2005.05.084.Full Text Link to Item
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Gharacholou, S Michael, and Karen P. Alexander. “Issues with care in the elderly patient presenting with acute ischemia.” Curr Cardiol Rep 7, no. 4 (July 2005): 270–75. https://doi.org/10.1007/s11886-005-0048-9.Full Text Link to Item
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DeLong, E. R., B. L. Lytle, P. A. Cowper, K. P. Alexander, E. D. Peterson, and D. B. Mark. “Research, managed care, and patient privacy: Challenges to successful collaboration.” Journal of Clinical Outcomes Management 12, no. 3 (March 1, 2005): 151–56.
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Mehta, Rajendra H., Christopher B. Granger, Karen P. Alexander, Eduardo Bossone, Harvey D. White, and Michael H. Sketch. “Reperfusion strategies for acute myocardial infarction in the elderly: benefits and risks.” J Am Coll Cardiol 45, no. 4 (February 15, 2005): 471–78. https://doi.org/10.1016/j.jacc.2004.10.065.Full Text Link to Item
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Mehta, S. R., S. Yusuf, R. Díaz, J. Zhu, P. Pais, D. Xavier, E. Paolasso, et al. “Effect of glucose-insulin-potassium infusion on mortality in patients with acute ST-segment elevation myocardial infarction: The CREATE-ECLA randomized controlled trial.” Journal of the American Medical Association 293, no. 4 (2005): 437–46. https://doi.org/10.1001/jama.293.4.437.Full Text
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Heitner, John F., Igor Klem, Karen Alexander, Louise Thomson, Trip J. Meine, Manesh R. Patel, Salman A. Haq, Dipan J. Shah, and Raymond J. Kim. “The case of the disappearing myxoma.” J Cardiovasc Magn Reson 7, no. 5 (2005): 841–43. https://doi.org/10.1080/10976640500288156.Full Text Link to Item
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Parsons, Elizabeth, L Kristin Newby, Manjushri V. Bhapkar, Karen P. Alexander, Harvey D. White, Svati H. Shah, Cheryl D. Bushnell, Robert M. Califf, and Robert M. Symphony and 2nd Symphony Investigators. “Postmenopausal hormone use in women with acute coronary syndromes.” J Womens Health (Larchmt) 13, no. 8 (October 2004): 863–71. https://doi.org/10.1089/jwh.2004.13.863.Full Text Link to Item
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Peterson, Eric D., Karen P. Alexander, David J. Malenka, Edward L. Hannan, Gerald T. O’Conner, Ben D. McCallister, William S. Weintraub, Fred L. Grover, and Fred L. American Heart Association Chronic CAD Working Group. “Multicenter experience in revascularization of very elderly patients.” Am Heart J 148, no. 3 (September 2004): 486–92. https://doi.org/10.1016/j.ahj.2004.03.039.Full Text Link to Item
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Alexander, Karen P., and Mimi S. Biswas. “Heart failure and the elderly: disease diversity, data, and delivery of care.” Am Heart J 146, no. 2 (August 2003): 194–96. https://doi.org/10.1016/S0002-8703(03)00190-X.Full Text Link to Item
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Jones, D. L., M. Ishii, A. LaPerriere, H. Stanley, M. Antoni, G. Ironson, N. Schneiderman, et al. “Influencing medication adherence among women with AIDS.” Aids Care 15, no. 4 (August 2003): 463–74. https://doi.org/10.1080/0954012031000134700.Full Text Link to Item
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Alexander, Karen P., and Eric D. Peterson. “Evidence-based care for all patients.” Am J Med 114, no. 4 (March 2003): 333–35. https://doi.org/10.1016/s0002-9343(03)00069-x.Full Text Link to Item
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Shah, S. H., K. P. Alexander, and E. D. Peterson. “PCI in women.” Cardiology Review 20, no. 3 (March 1, 2003): 24–29.
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Pasquali, Sara K., Karen P. Alexander, Laura P. Coombs, Barbara L. Lytle, and Eric D. Peterson. “Effect of cardiac rehabilitation on functional outcomes after coronary revascularization.” Am Heart J 145, no. 3 (March 2003): 445–51. https://doi.org/10.1067/mhj.2003.172.Full Text Link to Item
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Frazier, Camille, and Karen Alexander. “The finer points of race and hypertension.” Am Heart J 145, no. 2 (February 2003): 206–8. https://doi.org/10.1067/mhj.2003.108.Full Text Link to Item
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Shah, Svati H., and Karen P. Alexander. “Hormone Replacement Therapy for Primary and Secondary Prevention of Heart Disease.” Curr Treat Options Cardiovasc Med 5, no. 1 (February 2003): 25–33. https://doi.org/10.1007/s11936-003-0012-1.Full Text Link to Item
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Califf, Robert M., and Karen P. Alexander. “Cardiovascular research in the elderly: challenges, opportunities, and impact.” Postgraduate Medicine 112, no. 6 Suppl Heart (December 2002): 6–11. https://doi.org/10.3810/pgm.12.2002.suppl24.125.Full Text
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Alexander, K. P., M. V. Bhapkar, H. D. White, J. S. Hochman, M. E. Pfisterer, D. J. Moliterno, R. M. Califf, et al. “Paradoxical use of angiography with advancing age: Insights from an international trial population.” Journal of the American College of Cardiology 39, no. 5 (March 6, 2002): 152A-152A.Link to Item
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Alexander, K. P., T. Harding, L. P. Coombs, K. Taylor, and E. D. Peterson. “Aging and patient preferences regarding invasive cardiac care.” Journal of the American College of Cardiology 39, no. 5 (March 6, 2002): 197A-197A.Link to Item
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Pasquali, S. K., K. P. Alexander, L. P. Coombs, B. L. Lytle, and E. D. Peterson. “Effect of cardiac rehabilitation on functional outcomes following coronary revascularization.” Journal of the American College of Cardiology 39, no. 5 (March 6, 2002): 151A-151A.Link to Item
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Pasquali, S. K., K. P. Alexander, B. L. Lytle, L. P. Coombs, and E. D. Peterson. “Testing an intervention to increase cardiac rehabilitation enrollment after coronary artery bypass grafting.” Am J Cardiol 88, no. 12 (December 15, 2001): 1415-A6. https://doi.org/10.1016/s0002-9149(01)02123-3.Full Text Link to Item
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Pasquali, S. K., K. P. Alexander, and E. D. Peterson. “Cardiac rehabilitation in the elderly.” Am Heart J 142, no. 5 (November 2001): 748–55. https://doi.org/10.1067/mhj.2001.119134.Full Text Link to Item
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Alexander, K. P., and E. D. Peterson. “Medical and surgical management of coronary artery disease in women.” Am J Manag Care 7, no. 10 (October 2001): 951–56.Link to Item
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Lee, P. Y., K. P. Alexander, B. G. Hammill, S. K. Pasquali, and E. D. Peterson. “Representation of elderly persons and women in published randomized trials of acute coronary syndromes.” Jama 286, no. 6 (August 8, 2001): 708–13. https://doi.org/10.1001/jama.286.6.708.Full Text Link to Item
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Alexander, K. P., A. N. Galanos, J. G. Jollis, J. A. Stafford, and E. D. Peterson. “Post-myocardial infarction risk stratification in elderly patients.” Am Heart J 142, no. 1 (July 2001): 37–42. https://doi.org/10.1067/mhj.2001.115589.Full Text Link to Item
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Alexander, K. P., L. K. Newby, A. S. Hellkamp, R. A. Harrington, E. D. Peterson, S. Kopecky, A. Langer, et al. “Initiation of hormone replacement therapy after acute myocardial infarction is associated with more cardiac events during follow-up.” J Am Coll Cardiol 38, no. 1 (July 2001): 1–7. https://doi.org/10.1016/s0735-1097(01)01329-8.Full Text Link to Item
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Alexander, J. H., K. P. Alexander, P. J. Joski, M. S. Cuffe, and R. H. Peter. “Morbidly obese patients undergoing cardiac catheterization: Less disease, less aggressive revascularization, and similar outcomes.” Journal of the American College of Cardiology 37, no. 2 (February 1, 2001): 367A-368A.Link to Item
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Lee, P. Y., K. P. Alexander, B. G. Hammill, S. K. Pasquali, and E. D. Peterson. “Representation of the elderly in cardiovascular clinical trials.” Journal of the American College of Cardiology 37, no. 2 (February 1, 2001): 497A-497A.Link to Item
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Alexander, K. P., D. J. Malenka, E. L. Hannan, B. D. McCallister, and E. D. Peterson. “Outcomes of PCI in the aged: Results from 6 large registries.” Circulation 102, no. 18 (October 31, 2000): 642–642.Link to Item
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Alexander, K. P., L. L. Barbara, L. L. Choi, M. B. Daniel, and P. D. Eric. “Women have worse functional outcomes following bypass surgery.” Circulation 102, no. 18 (October 31, 2000): 839–839.Link to Item
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Bahit, M. C., C. B. Granger, K. P. Alexander, J. Kramer, N. M. A. Lapointe, and R. M. Califf. “Applying the evidence: Opportunity in US for 80,000 additional lives saved per year.” Circulation 102, no. 18 (October 31, 2000): 873–873.Link to Item
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Peterson, E. D., K. P. Alexander, G. T. O’Connor, F. L. Grover, E. L. Hannan, B. D. McCallister, and W. S. Weintraub. “The safety of coronary artery bypass surgery in the aged.” Circulation 102, no. 18 (October 31, 2000): 680-+.Link to Item
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Alexander, K. P., K. J. Anstrom, L. H. Muhlbaier, R. D. Grosswald, P. K. Smith, R. H. Jones, and E. D. Peterson. “Outcomes of cardiac surgery in patients > or = 80 years: results from the National Cardiovascular Network.” J Am Coll Cardiol 35, no. 3 (March 1, 2000): 731–38. https://doi.org/10.1016/s0735-1097(99)00606-3.Full Text Link to Item
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Alexander, K., L. J. Shaw, L. K. Shaw, E. DeLong, D. Mark, and E. Peterson. “Erratum: Value of exercise treadmill testing in women. Low dose dobutamine echocardiography predicts improvement in functional capacity after exercise training in patients with ischemic cardiomyopathy (Journal of the American College of Cardiology (1998) 32 (1657-1664)).” Journal of the American College of Cardiology 33, no. 1 (February 10, 1999): 289. https://doi.org/10.1016/S0735-1097(98)00655-X.Full Text
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Alexander, K. P., E. D. Peterson, C. B. Granger, A. C. Casas, F. Van de Werf, P. W. Armstrong, A. Guerci, E. J. Topol, and R. M. Califf. “Potential impact of evidence-based medicine in acute coronary syndromes: insights from GUSTO-IIb. Global Use of Strategies to Open Occluded Arteries in Acute Coronary Syndromes trial.” J Am Coll Cardiol 32, no. 7 (December 1998): 2023–30. https://doi.org/10.1016/s0735-1097(98)00466-5.Full Text Link to Item
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Alexander, K. P., L. J. Shaw, L. K. Shaw, E. R. Delong, D. B. Mark, and E. D. Peterson. “Value of exercise treadmill testing in women.” J Am Coll Cardiol 32, no. 6 (November 15, 1998): 1657–64. https://doi.org/10.1016/s0735-1097(98)00451-3.Full Text Link to Item
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Peterson, E. D., and K. P. Alexander. “Learning to suspect the unexpected: evaluating women with cardiac syndromes.” Am Heart J 136, no. 2 (August 1998): 186–88. https://doi.org/10.1053/hj.1998.v136.89736.Full Text Link to Item
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Alexander, J. H., K. Alexander, D. F. Kong, C. Y. Tung, and D. Whellan. “Session highlights from the American Heart Association Scientific Sessions: November 9-12, 1997.” Am Heart J 135, no. 1 (January 1998): 157–80. https://doi.org/10.1016/s0002-8703(98)70357-6.Full Text Link to Item
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Alexander, K. P., and E. D. Peterson. “Coronary artery bypass grafting in the elderly.” Am Heart J 134, no. 5 Pt 1 (November 1997): 856–64. https://doi.org/10.1016/s0002-8703(97)80008-7.Full Text Link to Item
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Alexander, K. P., E. D. Peterson, L. H. Muhlbaier, R. D. Grosswald, and M. J. Lanzilotta. “Cardiac surgery outcomes in 3,220 octogenarians: Results from the National Cardiovascular Network.” Circulation 96, no. 8 (October 21, 1997): 59–59.Link to Item
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Alexander, K. P., E. D. Peterson, N. E. ClappChanning, L. C. Lam, R. B. Williams, and D. B. Mark. “Functional outcome of CABG in the elderly.” Circulation 96, no. 8 (October 21, 1997): 2066–2066.Link to Item
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Alexander, K. P., E. D. Peterson, A. S. Hellkamp, C. B. Granger, E. J. Topol, and R. M. Califf. “Early catheterization is standard strategy in unstable angina/NQWMI: Results from GUSTO IIb.” Journal of the American College of Cardiology 29, no. 2 (February 1, 1997): 5614–5614.Link to Item
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Alexander, K. P., E. D. Peterson, K. W. Mahaffey, A. C. Casas, C. B. Granger, F. VandeWerf, P. W. Armstrong, D. B. Mark, E. J. Topol, and R. M. Califf. “Medical interventions in unstable angina: Does international clinical practice match evidence-based guidelines?” Journal of the American College of Cardiology 29, no. 2 (February 1, 1997): 23138–23138.Link to Item
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Alexander, K. P., and D. B. Mark. “Effect of gender on angioplasty outcome: are we closer to the answer?” Mayo Clin Proc 72, no. 1 (January 1997): 89–91. https://doi.org/10.4065/72.1.89.Full Text Link to Item
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Conference Papers
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Sidhu, Mandeep S., Karen P. Alexander, Zhen Huang, Sean M. O’Brien, Bernard R. Chaitman, Gregg W. Stone, Jonathan D. Newman, et al. “Causes of cardiovascular and noncardiovascular death in the ISCHEMIA trial.” In Am Heart J, 248:72–83, 2022. https://doi.org/10.1016/j.ahj.2022.01.017.Full Text Link to Item
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Rasmussen, P. V., M. L. Hansen, G. Gislason, J. Pallisgaard, M. Ruwald, C. B. Granger, R. D. Lopes, K. P. Alexander, S. M. Al-Khatib, and F. Dalgaard. “Older patients with atrial fibrillation and comorbidities are less likely to be treated with oral anticoagulation: insights from a nationwide study.” In European Heart Journal, 40:2978–2978. OXFORD UNIV PRESS, 2019.Link to Item
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Melloni, Chiara, Karen P. Alexander, Angie Wu, W Schuyler Jones, Rajendra H. Mehta, Robert W. Harrison, David Kong, et al. “Type 2 Myocardial Infarction: Incidence, Risk Factors, and Outcomes Among 41,581 Patients Enrolled in 3 Large Randomized Clinical Trials.” In Circulation, Vol. 140, 2019.Link to Item
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Dodson, John A., Terrence E. Murphy, Mary Geda, Harlan M. Krumholz, Sui Tsang, Alexandra Hajduk, Michael Nanna, et al. “A Readmission Risk Model for Older Adults Hospitalized With Acute Myocardial Infarction: The SILVER-AMI Study.” In Circulation, Vol. 138, 2018.Link to Item
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Alexander, Karen P., Kristi Prather, Kevin J. Anstrom, Daniel Mark, Ori Ben-Yehuda, Linda Davidson-Ray, Giora Weisz, Ramin Farzaneh-Far, Gregg Stone, and E Magnus Ohman. “Angina and Quality of Life Following PCI With Incomplete Revascularization: Results From the Ranolazine for Incomplete Vessel Revascularization (RIVER-PCI) Trial.” In Circulation, 132:2273–2273. LIPPINCOTT WILLIAMS & WILKINS, 2015.Link to Item
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Zimerman, Andre, Amanda L. Stebbins, Renato D. Lopes, Patricia O. Guimaraes, Stefan K. James, John H. Alexander, Pierluigi Tricoci, et al. “Adverse Event Reporting in > 48,000 Participants in Four Acute Coronary Syndrome Trials.” In Circulation, Vol. 132. LIPPINCOTT WILLIAMS & WILKINS, 2015.Link to Item
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Dodson, J. A., Y. Wang, S. I. Chaudhry, K. P. Alexander, F. A. Masoudi, J. A. Spertus, B. Nallamothu, et al. “National trends in rehospitalization for bleeding after acute myocardial infarction in the oldest old.” In Journal of the American Geriatrics Society, 62:S41–S41. WILEY-BLACKWELL, 2014.Link to Item
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Bagai, Akshay, Yongfei Wang, Tracy Y. Wang, Jeptha Curtis, Hitinder S. Gurm, Eric D. Peterson, Jorge F. Saucedo, et al. “In-Hospital ADP Receptor Inhibitor Switching in Myocardial Infarction Patients Treated With Percutaneous Coronary Intervention: Insights From the National Cardiovascular Data Registry (R).” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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Dodson, John A., Yun Wang, Karen P. Alexander, Fred Masoudi, John A. Spertus, Sarwat I. Chaudhry, Iersey Chen, et al. “National Trends in Rehospitalization for Bleeding After Acute Myocardial Infarction in Older Patients, 1999-2010.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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Shen, Lan, Shuang Li, Laine Thomas, Tracy Y. Wang, Karen P. Alexander, Bimal Shah, Eric Peterson, and Matthew T. Roe. “The Association of Transfer-out Rates from Hospitals Without Revascularization Capabilities and Long-term Mortality Risk Among Older Nstemi Patients.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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Dodson, John A., Kimberly J. Reid, Thomas M. Gill, Harlan M. Krumholz, Daniel E. Forman, John A. Spertus, Michael W. Rich, Suzanne V. Arnold, and Karen P. Alexander. “SLOW GAIT AMONG OLDER ADULTS POST-AMI AND RISK FOR HOSPITAL READMISSION.” In Journal of the American College of Cardiology, 59:E1914–E1914. Elsevier BV, 2012. https://doi.org/10.1016/s0735-1097(12)61915-9.Full Text
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Chin, Chee Tang, Tracy Y. Wang, Anita Y. Chen, Robin Mathews, Karen P. Alexander, Matthew T. Roe, and Eric D. Peterson. “COMPARISON OF TRENDS IN IN-HOSPITAL AND LONG-TERM OUTCOMES OVER TIME AMONG OLDER PATIENTS WITH NON-ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION: INSIGHTS FROM THE CRUSADE QUALITY IMPROVEMENT REGISTRY.” In Journal of the American College of Cardiology, 57:E905–E905. Elsevier BV, 2011. https://doi.org/10.1016/s0735-1097(11)60905-4.Full Text
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Desai, Nihar, Anita Y. Chen, Stephen D. Wiviott, Marc S. Sabatine, Karen P. Alexander, Matthew T. Roe, Eric D. Peterson, and Bimal R. Shah. “CHALLENGES IN THE TREATMENT OF NSTEMI PATIENTS AT HIGH RISK FOR BOTH ISCHEMIC AND BLEEDING EVENTS: INSIGHTS FROM THE ACTION REGISTRY-GWTG.” In Journal of the American College of Cardiology, 57:E913–E913. Elsevier BV, 2011. https://doi.org/10.1016/s0735-1097(11)60913-3.Full Text
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Fosbøl, Emil L., Tracy Y. Wang, Jonathan Piccini, Renato D. Lopes, Bimal Shah, Karen P. Alexander, Shuang Li, Matthew T. Roe, and Eric D. Peterson. “LONG-TERM SAFETY OF ANTITHROMBOTIC THERAPY IN NON-ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION PATIENTS WITH ATRIAL FIBRILLATION.” In Journal of the American College of Cardiology, 57:E948–E948. Elsevier BV, 2011. https://doi.org/10.1016/s0735-1097(11)60948-0.Full Text
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Martin, Seth S., Kensey Gosch, Krishnaji Kulkarni, John A. Spertus, Robin Mathews, L Kristin Newby, Karen P. Alexander, and Tracy Y. Wang. “PATIENT AND PROVIDER FACTORS IN LIPID GOAL ATTAINMENT AFTER ACUTE MYOCARDIAL INFARCTION: INSIGHTS FROM THE TRANSLATIONAL RESEARCH INVESTIGATING UNDERLYING DISPARITIES IN ACUTE MYOCARDIAL INFARCTION PATIENTS' HEALTH STATUS (TRIUMPH) STUDY.” In Journal of the American College of Cardiology, 57:E573–E573. Elsevier BV, 2011. https://doi.org/10.1016/s0735-1097(11)60573-1.Full Text
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Subherwal, Sumeet, Shuang Li, Manesh R. Patel, Deepak L. Bhatt, Tracy Y. Wang, Karen P. Alexander, E Magnus Ohman, W Brian Gibler, Eric D. Peterson, and Matthew T. Roe. “IMPACT OF POLYVASCULAR DISEASE ON LONG-TERM MORTALITY IN OLDER PATIENTS WITH NON-ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION.” In Journal of the American College of Cardiology, 57:E992–E992. Elsevier BV, 2011. https://doi.org/10.1016/s0735-1097(11)60992-3.Full Text
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Afilalo, Jonathan, Mark J. Eisenberg, Jean-Francois Morin, Howard Bergman, Johanne Monette, Nicolas Noiseux, Louis P. Perrault, et al. “Gait Speed as a Predictor of Mortality and Major Morbidity in Older Adults Undergoing Cardiac Surgery: Preliminary Results From the FRAILTY ABC'S Study.” In Circulation, 120:S988–89. LIPPINCOTT WILLIAMS & WILKINS, 2009.Link to Item
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Shah, Bimal R., Matthew T. Roe, Anita Y. Chen, Karen P. Alexander, Tracy Y. Wang, E Magnus Ohman, W Brian Gibler, and Eric D. Peterson. “Association Between Hospital Process Performance and 1-Year Post-discharge Mortality in Patients With Non-ST-elevation Myocardial Infarction: Results From 36,262 Patients.” In Circulation, 120:S1086–S1086. LIPPINCOTT WILLIAMS & WILKINS, 2009.Link to Item
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Tsai, Thomas T., Thomas M. Maddox, Matthew T. Roe, David Dai, Karen P. Alexander, P Michael Ho, John C. Messenger, Brahmajee K. Nallamothu, Eric D. Peterson, and John S. Rumsfeld. “Use of Contraindicated Anti-Thrombotics in Dialysis Patients Undergoing Percutaneous Coronary Interventions: Insights From the NCDR Cath-PCI Registry.” In Circulation, 120:S414–S414. LIPPINCOTT WILLIAMS & WILKINS, 2009.Link to Item
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Wang, Tracy Y., Anita Y. Chen, Bimal R. Shah, Matthew T. Roe, Karen P. Alexander, E Magnus Ohman, W Brian Gibler, and Eric D. Peterson. “Readmission Rates Among Patients With Non-ST-Segment Elevation Myocardial Infarction: Results in 38,131 Patients From the CRUSADE Quality Improvement Initiative.” In Circulation, 120:S436–37. LIPPINCOTT WILLIAMS & WILKINS, 2009.Link to Item
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Alexander, Karen P., Chiara Melloni, A. Pappas, L Kristin Newby, Nancy M Allen LaPointe, E Magnus Ohman, W Brian Gibler, Matthew T. Roe, and Eric D. Peterson. “Potency of statins track with intensity of overall secondary prevention.” In Circulation, 117:E453–E453. LIPPINCOTT WILLIAMS & WILKINS, 2008.Link to Item
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Melloni, Chiara, Karen P. Alexander, Fang-Shu Ou, Nancy M Allen LaPointe, Matthew T. Roe, and Eric D. Peterson. “Factors associated with patient reported self-discontinuation of prescribed medicine after non-ST-segment elevation acute coronary syndromes.” In Circulation, 117:E418–E418. LIPPINCOTT WILLIAMS & WILKINS, 2008.Link to Item
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Alexander, Karen P., Richard G. Bach, Anita Y. Chen, Sumeet Subherwal, Brian F. Gage, Sunil V. Rao, W Brian Gibler, et al. “Bleeding and ischemic events run parallel in NSTEMI patients.” In Journal of the American College of Cardiology, 51:A207–8. ELSEVIER SCIENCE INC, 2008.Link to Item
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Subherwal, Sumeet, Richard G. Bach, Anita Y. Chen, Brian F. Gage, Sunil V. Rao, Tracy Y. Wang, W Brian Gibler, et al. “The CRUSADE bleeding score to assess baseline risk of major bleeding in non-ST-segment elevation myocardial infarction.” In Journal of the American College of Cardiology, 51:A212–A212. ELSEVIER SCIENCE INC, 2008.Link to Item
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Wang, Tracy Y., Anita Y. Chen, Eric D. Peterson, Karen P. Alexander, E Magnus Ohman, W Brian Gibler, and Matthew T. Roe. “Incidence and bleeding outcomes of excess unfractionated heparin dosing among patients with ST-Segment elevation myocardial infarction undergoing fibrinolysis.” In Journal of the American College of Cardiology, 51:A203–A203. ELSEVIER SCIENCE INC, 2008.Link to Item
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Alexander, Karen P., Anita Y. Chen, Matthew T. Roe, L Kristin Newby, Brian Gibler, E Magnus Ohman, Charles V. Pollack, and Eric D. Peterson. “Decline in GP 2b3a inhibitor overdosing with site-specific feedback in CRUSADE.” In Circulation, 116:798–99. LIPPINCOTT WILLIAMS & WILKINS, 2007.Link to Item
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Wang, Tracy Y., Anita Y. Chen, Magnus Ohman, Karen P. Alexander, Charles V. Pollack, Sidney C. Smith, W Brian Gibler, Matthew T. Roe, and Eric D. Peterson. “Contemporary patterns of reperfusion for elderly patients with ST-segment elevation myocardial infarction.” In Circulation, 115:E582–E582. LIPPINCOTT WILLIAMS & WILKINS, 2007.Link to Item
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Alexander, Karen P., Patricia A. Cowper, Barbara L. Lylte, Judith A. Kempf, and Eric D. Peterson. “Predictors of persistent angina among coronary disease patients.” In Journal of the American College of Cardiology, 49:232A-232A. ELSEVIER SCIENCE INC, 2007.Link to Item
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Alexander, Karen P., Patricia A. Cowper, Barbara L. Lytle, Judith A. Kempf, and Eric D. Peterson. “Less is better, none is best: Angina and health related quality of life.” In Journal of the American College of Cardiology, 49:229A-229A. ELSEVIER SCIENCE INC, 2007.Link to Item
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Roe, Matthew T., Karen P. Alexander, Fang-Shou Ou, L Kristin Newby, W Brian Gibler, Charles V. Pollack, E Magnus Ohman, Sidney C. Smith, and Eric D. Peterson. “Patterns of HDL levels in patients with non-ST-segment elevation acute coronary syndromes and association with clinical outcomes.” In Journal of the American College of Cardiology, 49:366A-366A. ELSEVIER SCIENCE INC, 2007.Link to Item
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Wang, Tracy Y., Anita Y. Chen, Matthew T. Roe, Karen P. Alexander, L Kristin Newby, Sidney C. Smith, Sripal Bangalore, W Brian Gibler, E Magnus Ohman, and Eric D. Peterson. “Increased bleeding risk among Asians with non-ST-segment elevation acute coronary syndromes: Insights from the CRUSADE quality improvement initiative.” In Journal of the American College of Cardiology, 49:208A-208A. ELSEVIER SCIENCE INC, 2007.Link to Item
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Alexander, Karen P., E Magnus Ohman, Michel E. Bertrand, Frederic Feit, Charles V. Pollack, James Hoekstra, Bernard J. Gersh, Harvey D. White, and Gregg W. Stone. “Outcomes in elderly patients undergoing PCI treated with bivalirudin monotherapy versus glycoprotein IIb/IIIa inhibitors with hepaiin or LMWH: Results from the randomized ACUITY trial.” In American Journal of Cardiology, 98:18M-18M. EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC, 2006.Link to Item
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Mehta, R. H., E. D. Peterson, L. Liang, K. P. Alexander, W. B. Gibler, E. M. Ohman, C. V. Pollack, and M. T. Roe. “Contraindications to cardiac catheterization in non-ST-elevation acute coronary syndromes: Insights from the CRUSADE national quality improvement initiative.” In European Heart Journal, 27:183–183. OXFORD UNIV PRESS, 2006.Link to Item
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Alexander, Karen P., Jyotsna Mulgund, Barbara Lytle, and Eric Peterson. “Long-term implications of discharge anemia in a cardiovascular population.” In Circulation, 113:E795–E795. LIPPINCOTT WILLIAMS & WILKINS, 2006.Link to Item
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Dunlay, Shannon M., Li Liang, Chiara Melloni, Jennifer L. Kraschnewski, Karen P. Alexander, W Brian Gibler, Matthew T. Roe, E Magnus Ohman, and Eric D. Peterson. “Quality of medical record documentation in an acute coronary syndrome population: Results from CRUSADE.” In Circulation, 113:E802–3. LIPPINCOTT WILLIAMS & WILKINS, 2006.Link to Item
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LaPointe, N. M. A., K. P. Alexander, A. Y. Chen, M. T. Roe, C. V. Pollack, E. M. Ohman, W. B. Gibler, and E. D. Peterson. “Enoxaparin dosing and bleeding in real world practice: Results from CRUSADE.” In Journal of the American College of Cardiology, 47:235A-235A. ELSEVIER SCIENCE INC, 2006.Link to Item
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Peterson, E. D., A. Y. Chen, K. P. Alexander, N. M. A. LaPointe, E. S. Fraulo, L. K. Newby, M. T. Roe, W. B. Gibler, and E. M. Ohman. “The association between hospital guideline adherence, dosing safety, and patient outcomes: Results from the CRUSADE quality improvement initiative.” In Journal of the American College of Cardiology, 47:255A-255A. ELSEVIER SCIENCE INC, 2006.Link to Item
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Alexander, K. P., A. Y. Chen, M. T. Roe, L. K. Newby, C. M. Gibson, J. Schwartz, J. S. Hochman, et al. “Sex differences in glycoprotein 11b/111a inhibitor dosing and bleeding in acute coronary syndromes: Results from CRUSADE.” In Circulation, 112:U491–92. LIPPINCOTT WILLIAMS & WILKINS, 2005.Link to Item
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Melloni, C., M. T. Roe, S. Milford-Boland, K. P. Alexander, L. K. Newby, L. A. Szczech, C. V. Pollack, et al. “Renal insufficiency, troponin, and risk of death among patients with non-ST-segment elevation acute coronary syndromes.” In Circulation, 112:U587–88. LIPPINCOTT WILLIAMS & WILKINS, 2005.Link to Item
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Spinler, S., K. P. Alexander, A. Y. Chen, M. T. Roe, W. B. Gibler, M. Ohman, and E. D. Peterson. “Predictors of excess dosing of injectable antithrombotics in patients with non-ST-segment elevation acute coronary syndromes.” In Pharmacotherapy, 25:1437–38. PHARMACOTHERAPY PUBLICATIONS INC, 2005.Link to Item
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Alexander, K. P., A. Y. Chen, M. T Roe, L. K. Newby, W. B. Gibler, E. M. Ohman, and E. D. Peterson. “Antiplatelet and antithrombin dose variation in patients with non-ST-segment elevation acute coronary syndromes.” In Circulation, 111:E312–13. LIPPINCOTT WILLIAMS & WILKINS, 2005.Link to Item
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Alexander, K. P., J. L. Sun, T. Harding, and B. Lee. “Who is right and what matters? Frailty in patients with cardiovascular disease.” In Circulation, 111:E339–40. LIPPINCOTT WILLIAMS & WILKINS, 2005.Link to Item
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Lytle, Barbara L., Gregory J. Shook, Karen P. Alexander, Patricia A. Cowper, Daniel B. Mark, and Elizabeth R. DeLong. “1153-74 Physician counseling can influence health-related quality of life.” In Journal of the American College of Cardiology, 43:A418–A418. Elsevier BV, 2004. https://doi.org/10.1016/s0735-1097(04)91763-9.Full Text
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Alexander, K. P., B. Lytle, Y. Li, and E. Peterson. “Elderly patients have better functioning, less angina at one year with coronary artery bypass graft.” In Journal of the American College of Cardiology, 41:220A-221A. ELSEVIER SCIENCE INC, 2003.Link to Item
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Alexander, K. P., T. Harding, L. Coombs, and E. Peterson. “Are patients properly informed prior to revascularization decisions?” In Journal of the American College of Cardiology, 41:535A-535A. ELSEVIER SCIENCE INC, 2003.Link to Item
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Lytle, B. L., L. P. Coombs, G. J. Shook, P. A. Cowper, K. P. Alexander, E. D. Peterson, D. B. Mark, and E. R. DeLong. “Home health care for coronary artery disease patients impacts quality of life.” In Journal of the American College of Cardiology, 41:521A-521A. ELSEVIER SCIENCE INC, 2003.Link to Item
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Biswas, M. S., E. L. Eisenstein, and K. P. Alexander. “The right test for the right price.” In Circulation, 106:759–759. LIPPINCOTT WILLIAMS & WILKINS, 2002.Link to Item
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