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Karen Patton Alexander

Professor of Medicine
Medicine, Cardiology
Duke Box 3411, Durham, NC 27710
200 Morris St, Durham, NC 27701


My research focus is on cardiovascular disease management and outcomes in special populations, specifically older adults. Historically there has been a lack of randomized controlled data regarding treatment efficacy and outcomes in this growing population. Because of this, certain therapies may have different risk benefit profiles, which may cause physicians to alter their therapeutic interventions. My research explores evidence based treatment for older adults, including preferences and decision-making as well as frailty and aging assessments in clinical trials and registries. Diagnosis and management of stable ischemic heart disease is also an area of focus.

Current Appointments & Affiliations

Professor of Medicine · 2015 - Present Medicine, Cardiology, Medicine
Member in the Duke Clinical Research Institute · 1995 - Present Duke Clinical Research Institute, Institutes and Centers

Education, Training & Certifications

Duke University · 1992 M.D.