Overview
My current research interest is in understanding the mechanisms of cardiovascular disease among patients with chronic kidney disease, with a particular focus on the epidemic of sudden cardiac death. The ultimate goal is to reduce the impact of sudden death through improved risk stratification and novel risk mitigation therapies. Current investigations are focused on identifying novel genetic and biomarker risk factors among CKD patients, understanding the interplay of hemodialysis-specific exposures in the development of arrhythmias, and examining the risks and benefits of implantable cardioverter defibrillators among CKD patients using clinical trial and registry data.
Current Appointments & Affiliations
Associate Professor of Medicine
·
2020 - Present
Medicine, Nephrology,
Medicine
Member in the Duke Clinical Research Institute
·
2015 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Discrete Time Neural Network Models to Address Time-Varying Predictor Importance: An Illustration in Predicting Mortality Over Different Time Horizons.
Journal Article IEEE J Biomed Health Inform · January 2026 Clinical predictive models (CPMs) are crucial for forecasting patient outcomes using available electronic health record (EHR) data. Traditional time-to-event (TTE) models, like the Cox proportional hazards model, assume that hazard ratios remain constant o ... Full text Link to item CiteChronic Pain Locations, Characteristics, and Associations With Other Symptoms in Adults Receiving Maintenance Hemodialysis: Findings From the HOPE Consortium Trial.
Journal Article Am J Kidney Dis · November 17, 2025 RATIONALE & OBJECTIVE: Adults receiving maintenance hemodialysis (HD) frequently report pain, yet detailed descriptions of pain in this population are lacking. This study examines pain locations, characteristics, and associations with other symptoms in adu ... Full text Link to item CiteLong-term outcomes of subcutaneous versus transvenous implantable cardioverter defibrillator use among patients on maintenance dialysis.
Journal Article Heart Rhythm · November 2025 BACKGROUND: Despite an elevated risk of sudden cardiac death among dialysis patients, implantable cardioverter defibrillators (ICDs) have not been shown to improve mortality and are associated with high complication rates. Subcutaneous (S-)ICDs may reduce ... Full text Link to item CiteRecent Grants
TRIO NRSA Training Core-Post Doc Trainee
Inst. Training Prgm or CMEMentor · Awarded by University of North Carolina - Chapel Hill · 2023 - 2028QT prolonging medications and sudden cardiac death among individuals on hemodialysis
ResearchPrincipal Investigator · Awarded by University of North Carolina - Chapel Hill · 2020 - 2025Association Between ECG data obtained via the Medtronic Reveal LINQ device and Real-Time Blood Chemistry Values: RADAR Ancillary Study Proposal
Clinical TrialPrincipal Investigator · Awarded by New York University School of Medicine · 2018 - 2025View All Grants
Education, Training & Certifications
Vanderbilt University ·
2001
M.D.