Overview
My current research interest is in understanding the mechanisms of cardiovascular disease among patients with chronic kidney disease, with a particular focus on the epidemic of sudden cardiac death. The ultimate goal is to reduce the impact of sudden death through improved risk stratification and novel risk mitigation therapies. Current investigations are focused on identifying novel genetic and biomarker risk factors among CKD patients, understanding the interplay of hemodialysis-specific exposures in the development of arrhythmias, and examining the risks and benefits of implantable cardioverter defibrillators among CKD patients using clinical trial and registry data.
Current Appointments & Affiliations
Associate Professor of Medicine
·
2020 - Present
Medicine, Nephrology,
Medicine
Member in the Duke Clinical Research Institute
·
2015 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Association of chronic kidney disease and kidney failure with replacement therapy with procedural and long-term outcomes after first-generation Watchman device: Insights from the NCDR LAAO Registry.
Journal Article Heart Rhythm · June 2025 BACKGROUND: Chronic kidney disease (CKD) and kidney failure with replacement therapy (KFRT) are prevalent in patients with atrial fibrillation (AF). OBJECTIVE: The purpose of this study was to analyze procedural and long-term outcomes in AF patients with u ... Full text Link to item CiteTiming and Location of Sudden Cardiac Arrests in Hemodialysis Patients: Be Prepared for the Expected.
Journal Article Kidney360 · May 1, 2025 Full text Link to item CiteCardiac Arrest in Outpatient Hemodialysis Units: A National Cross-Sectional Survey of Dialysis Technicians.
Journal Article Am J Kidney Dis · February 28, 2025 RATIONALE & OBJECTIVE: Cardiac arrest is the leading cause of death for hemodialysis patients and often occurs within outpatient dialysis units. Approximately one-fifth of dialysis unit resuscitations are not initiated until emergency medical service perso ... Full text Link to item CiteRecent Grants
QT prolonging medications and sudden cardiac death among individuals on hemodialysis
ResearchPrincipal Investigator · Awarded by University of North Carolina - Chapel Hill · 2020 - 2025Association Between ECG data obtained via the Medtronic Reveal LINQ device and Real-Time Blood Chemistry Values: RADAR Ancillary Study Proposal
Clinical TrialPrincipal Investigator · Awarded by New York University School of Medicine · 2018 - 2025A Phase 3, Intravenous Sodium Thiosulfate for Acute Calciphylaxis Treatment: A Multicenter, Randomized, Double-blind, Placebo-controlled, Clinical Trial
Clinical TrialPrincipal Investigator · Awarded by Hope Pharmaceuticals Inc. · 2019 - 2022View All Grants
Education, Training & Certifications
Vanderbilt University ·
2001
M.D.