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Thomas Lawrence Holland

Professor of Medicine
Medicine, Infectious Diseases
Duke Box 102359, Durham, NC 27710
Room 163 Hanes House, Trent Drive, Durham, NC 27710

Current Duke Appointments & Affiliations


Professor of Medicine · 2024 - Present Medicine, Infectious Diseases, Medicine
Membership in the Duke Clinical Research Institute · 2015 - Present Duke Clinical Research Institute, Institutes and Centers

Recent News Items


Published October 4, 2023
Drug Found Effective in Fighting Deadly Infections
Published July 11, 2022
Monoclonal Antibody Treatment Reduced Deaths in Hospitalized COVID Patients
Published September 26, 2018
New Way of Determining Treatment for Staph Infections Cuts Antibiotic Use

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Recent Scholarly Works


Escherichia coli ST131 Drives Carbapenem Use for E. coli Bloodstream Infections.

Journal article Clin Infect Dis · July 23, 2026 BACKGROUND: Ceftriaxone-resistant Escherichia coli infections are increasingly common, partially because of the emergence of E. coli sequence type 131 (ST131), including its subclade C2/H30Rx, which produce extended-spectrum β-lactamases. METHODS: A prospe ... Full text Link to item Cite

Ceftobiprole and the kidney: secondary analyses of the ERADICATE Staphylococcus aureus bacteraemia trial

Journal article Cmi Communications · July 1, 2026 Objectives Ceftobiprole demonstrated noninferiority to daptomycin for the treatment of Staphylococcus aureus bacteraemia. A range of post hoc exploratory analyses were undertaken to better inform additional key clinical questions—including how ceftobiprole ... Full text Cite
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Recent Grants


A PHASE 3 EFFICACY AND SAFETY STUDY OF FOSMANOGEPIX FOR THE TREATMENT OF ADULT PARTICIPANTS WITH CANDIDEMIA AND/OR INVASIVE CANDIDIASIS

ResearchInvestigator · Awarded by Basilea Pharmaceutica International Ltd, Allschwil · 2025 - 2028

Invasive Candidiasis

Clinical TrialPrincipal Investigator · Awarded by Basilea Pharmaceutica · 2024 - 2028

Antibacterial Resistance Leadership Group (ARLG)

ResearchCo Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2013 - 2026

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Education


Wake Forest University · 2005 M.D.