Cagla Eroglu
Professor of Cell Biology
Current Appointments & Affiliations
- Professor of Cell Biology, Cell Biology, Basic Science Departments 2022
- Professor of Neurobiology, Neurobiology, Basic Science Departments 2022
- Faculty Network Member of the Duke Institute for Brain Sciences, Duke Institute for Brain Sciences, University Institutes and Centers 2008
- Associate of the Duke Initiative for Science & Society, Duke Science & Society, Initiatives 2018
- Affiliate of the Duke Regeneration Center, Regeneration Next Initiative, Basic Science Departments 2021
Contact Information
- 333A Nanaline Duke Bldg, Durham, NC 27710
- Duke Box 3709, Durham, NC 27710
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c.eroglu@cellbio.duke.edu
(919) 684-3605
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Department of Cell Biology
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Eroglu Lab Website
- Background
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Education, Training, & Certifications
- Ph.D., Ruprecht Karl University (Germany) 2002
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Previous Appointments & Affiliations
- Associate Professor of Cell Biology, Cell Biology, Basic Science Departments 2016 - 2022
- Associate Professor of Neurobiology, Neurobiology, Basic Science Departments 2016 - 2022
- Assistant Professor of Cell Biology, Cell Biology, Basic Science Departments 2008 - 2016
- Assistant Professor of Neurobiology, Neurobiology, Basic Science Departments 2009 - 2016
- Recognition
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In the News
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MAY 4, 2023 Duke Today -
APR 5, 2023 School of Medicine -
SEP 17, 2021 -
JUN 24, 2021 -
NOV 12, 2020 -
APR 14, 2020 -
JAN 21, 2020 -
SEP 5, 2018 -
MAR 6, 2018 -
NOV 8, 2017 -
JAN 13, 2016 -
NOV 24, 2015 -
JAN 6, 2015 -
DEC 9, 2014 Duke Research Blog -
JUL 8, 2014
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Awards & Honors
- Research
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Selected Grants
- Duke Preparing Research Scholars in Biomedical Sciences- Post-Baccalaureate Research Education Program awarded by National Institutes of Health 2022 - 2027
- Medical Scientist Training Program awarded by National Institutes of Health 2022 - 2027
- Training Program in Developmental and Stem Cell Biology awarded by National Institutes of Health 2001 - 2027
- Cell and Molecular Biology Training Program awarded by National Institutes of Health 2021 - 2026
- NIDDK NRSA T32 Diversity Administrative Supplement awarded by National Institutes of Health 2021 - 2026
- Targeting tumor-neural cell interactions to inhibit lung cancer brain metastasis awarded by National Institutes of Health 2021 - 2026
- Neuron-Microglia Crosstalk in Development: A new role for the neuron-derived cytokine IL34 in microglial function awarded by National Institutes of Health 2022 - 2025
- Genetic and Genomics Training Grant awarded by National Institutes of Health 2020 - 2025
- Duke Creating ADRD Researchers for the Next Generation - Stimulating Access to Research in Residency Program (CARiNG-StARR)" awarded by National Institutes of Health 2020 - 2024
- CIRCUIT MECHANISMS FOR DOPAMINE NEURON VULNERABILITY AND RESILIENCE IN PD awarded by Michael J. Fox Foundation for Parkinson's Research 2021 - 2024
- Mitochondria Regulation of Astrocyte Development and Synaptogenic Function awarded by Howard Hughes Medical Institute 2021 - 2024
- Neurobiology Training Program awarded by National Institutes of Health 2019 - 2024
- A novel role for astrocyte-secreted synaptogenic factor Hevin/SPARCL1 in microglia-mediated synaptic pruning in response to visual experience awarded by National Institutes of Health 2022 - 2024
- Role of astrocytes in demyelination and myelin repair awarded by Adelson Foundation 2022 - 2023
- Linking Neuron-Astrocyte Communication to Long-Term Changes in Neural Circuit Function and Behavior awarded by Salk Institute Biotechnology/Industrial Associatio 2021 - 2023
- Heat Shock Factors and Protein Misfolding Disease awarded by National Institutes of Health 2018 - 2023
- Control of Astrocyte Development and Astrocyte-Synapse Interactions awarded by National Institutes of Health 2018 - 2023
- Dissecting the link between astrocyte diversity and PD risk awarded by Chan Zuckerberg Initiative 2021 - 2022
- Role of Dysfunction Astrocyte-Neuron Signaling in Parkinson's Disease awarded by Chan Zuckerberg Initiative 2021 - 2022
- Discovering the Astrocytic Compartment of Dopaminergic Synapses in Health and PD. awarded by Ruth K. Broad Biomedical Research Foundation 2021 - 2022
- How do Astrocytes Control Inhibitory Synapse Formation and Function? awarded by Pew Charitable Trusts Latin American Fellows Prog 2018 - 2022
- Zeiss Lightsheet Upgrade to Expand Imaging Capabilities awarded by National Institutes of Health 2021 - 2022
- CZI Neurodegeneration Community Projects awarded by Chan Zuckerberg Initiative 2021 - 2022
- Control of Astrocyte Morphogenesis and Synaptogenesis by Astrocytic Neuroligins awarded by National Institutes of Health 2019 - 2022
- CZI Neurodegeneration Community Projects awarded by Chan Zuckerberg Initiative 2019 - 2021
- New Proteomic and Genome Engineering Approaches to Decipher Astrocyte Function at Synapses awarded by National Institutes of Health 2018 - 2021
- Control of Astrocyte Function by Parkinsonism Gene LRRK2 awarded by Michael J. Fox Foundation for Parkinson's Research 2019 - 2021
- Transmission electron microscope (TEM) awarded by National Institutes of Health 2019 - 2021
- Environmental Toxins and Microglia-Synapse Interactions in Autism awarded by National Institutes of Health 2016 - 2021
- Super-resolution Imaging via Multiple Modalities with the Zeiss Elyra 7 awarded by National Institutes of Health 2020 - 2021
- The Regulation of Synaptic Connectivity and Homeostasis by Huntingtin awarded by National Institutes of Health 2016 - 2020
- Genetics Training Grant awarded by National Institutes of Health 1979 - 2020
- Organization and Function of Cellular Structure awarded by National Institutes of Health 1975 - 2020
- How Does Huntingtin Control Synaptic Development? awarded by National Institutes of Health 2018 - 2020
- Control of Excitatory Synapse Formation by Huntingtin awarded by National Institutes of Health 2017 - 2020
- How Do Muller Glia Control Circuit-Specific Retinal Synaptogenesis? awarded by National Institutes of Health 2017 - 2019
- Environmental Toxins and Microglia-Synapse Interactions in Autism awarded by Massachusetts General Hospital 2016 - 2019
- Control of Excitatory Synaptogenesis by Huntingtin awarded by Ruth K. Broad Biomedical Research Foundation 2017 - 2018
- Basic predoctoral training in neuroscience awarded by National Institutes of Health 1992 - 2018
- Targeting Autonomic Dysreflexia to Restore Immune Function After Spinal Injury awarded by Ohio State University 2014 - 2018
- Serial Block Face Scanning Electron Microscope awarded by National Institutes of Health 2016 - 2018
- Control of synapse formation and maturation by astrocytes awarded by National Institutes of Health 2012 - 2018
- Sex Differences in Developing Microglia: Implications for Synaptic Pruning awarded by Massachusetts General Hospital 2016 - 2018
- Investigation of the effects of hUTC on Mueller glia awarded by Janssen Research & Development, LLC 2017 - 2018
- Control of Tripartite Synapse Formation by Astrocytic Neuroligins awarded by National Institutes of Health 2015 - 2018
- Sex Differences in Developing Microglia: Implications for Synaptic Pruning awarded by National Institutes of Health 2013 - 2016
- Training in Fundamental &Translational Neuroscience awarded by National Institutes of Health 2005 - 2016
- Control of Excitatory Synapse Formation and Maturation by Astrocytes awarded by National Institutes of Health 2013 - 2015
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Chen, Gang, Jing Xu, Hao Luo, Xin Luo, Sandeep K. Singh, Juan J. Ramirez, Michael L. James, et al. “Hevin/Sparcl1 drives pathological pain through spinal cord astrocyte and NMDA receptor signaling.” Jci Insight 7, no. 23 (December 8, 2022). https://doi.org/10.1172/jci.insight.161028.Full Text Open Access Copy Link to Item
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Block, Carina L., Oznur Eroglu, Stephen D. Mague, Caroline J. Smith, Alexis M. Ceasrine, Chaichontat Sriworarat, Cameron Blount, et al. “Prenatal environmental stressors impair postnatal microglia function and adult behavior in males.” Cell Rep 40, no. 5 (August 2, 2022): 111161. https://doi.org/10.1016/j.celrep.2022.111161.Full Text Link to Item
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Baumert, Ryan, Nicholas Brose, and Cagla Eroglu. “Astrocytic traffic jams in the aging brain.” Nature Aging 2, no. 8 (August 2022): 681–83. https://doi.org/10.1038/s43587-022-00270-4.Full Text
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Lawal, Oluwadamilola, Francesco Paolo Ulloa Severino, and Cagla Eroglu. “The role of astrocyte structural plasticity in regulating neural circuit function and behavior.” Glia 70, no. 8 (August 2022): 1467–83. https://doi.org/10.1002/glia.24191.Full Text Link to Item
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Taketomi, Takumi, Takunori Yasuda, Rikuri Morita, Jaehyun Kim, Yasuteru Shigeta, Cagla Eroglu, Ryuhei Harada, and Fuminori Tsuruta. “Autism-associated mutation in Hevin/Sparcl1 induces endoplasmic reticulum stress through structural instability.” Sci Rep 12, no. 1 (July 13, 2022): 11891. https://doi.org/10.1038/s41598-022-15784-5.Full Text Link to Item
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Baldwin, Katherine T., Christabel X. Tan, Samuel T. Strader, Changyu Jiang, Justin T. Savage, Xabier Elorza-Vidal, Ximena Contreras, et al. “HepaCAM controls astrocyte self-organization and coupling.” Neuron 109, no. 15 (August 4, 2021): 2427-2442.e10. https://doi.org/10.1016/j.neuron.2021.05.025.Full Text Link to Item
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Tan, Christabel X., and Cagla Eroglu. “Cell adhesion molecules regulating astrocyte-neuron interactions.” Curr Opin Neurobiol 69 (August 2021): 170–77. https://doi.org/10.1016/j.conb.2021.03.015.Full Text Link to Item
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Ramirez, Juan J., Dhanesh Sivadasan Bindu, and Cagla Eroglu. “Building and destroying synaptic bridges: How do Hevin/Sparcl1, SPARC, and MDGAs modify trans-synaptic neurexin-neuroligin interactions?” Structure 29, no. 7 (July 1, 2021): 635–37. https://doi.org/10.1016/j.str.2021.06.011.Full Text Link to Item
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Brennan, Faith H., Benjamin T. Noble, Yan Wang, Zhen Guan, Hayes Davis, Xiaokui Mo, Clay Harris, Cagla Eroglu, Adam R. Ferguson, and Phillip G. Popovich. “Acute post-injury blockade of α2δ-1 calcium channel subunits prevents pathological autonomic plasticity after spinal cord injury.” Cell Rep 34, no. 4 (January 26, 2021): 108667. https://doi.org/10.1016/j.celrep.2020.108667.Full Text Link to Item
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Takano, Tetsuya, John T. Wallace, Katherine T. Baldwin, Alicia M. Purkey, Akiyoshi Uezu, Jamie L. Courtland, Erik J. Soderblom, et al. “Chemico-genetic discovery of astrocytic control of inhibition in vivo.” Nature 588, no. 7837 (December 2020): 296–302. https://doi.org/10.1038/s41586-020-2926-0.Full Text Link to Item
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Ostrovskaya, Olga I., Guan Cao, Cagla Eroglu, and Kristen M. Harris. “Developmental onset of enduring long-term potentiation in mouse hippocampus.” Hippocampus 30, no. 12 (December 2020): 1298–1312. https://doi.org/10.1002/hipo.23257.Full Text
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Risher, William Christopher, and Cagla Eroglu. “Emerging roles for α2δ subunits in calcium channel function and synaptic connectivity.” Curr Opin Neurobiol 63 (August 2020): 162–69. https://doi.org/10.1016/j.conb.2020.04.007.Full Text Link to Item
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Luo, Lin, Mateusz C. Ambrozkiewicz, Fritz Benseler, Cui Chen, Emilie Dumontier, Susanne Falkner, Elisabetta Furlanis, et al. “Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors.” Neuron 106, no. 1 (April 8, 2020): 37-65.e5. https://doi.org/10.1016/j.neuron.2020.01.008.Full Text Link to Item
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Burrus, Caley J., Spencer U. McKinstry, Namsoo Kim, M Ilcim Ozlu, Aditya V. Santoki, Francia Y. Fang, Annie Ma, et al. “Striatal Projection Neurons Require Huntingtin for Synaptic Connectivity and Survival.” Cell Rep 30, no. 3 (January 21, 2020): 642-657.e6. https://doi.org/10.1016/j.celrep.2019.12.069.Full Text Link to Item
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Koh, Sehwon, Suva Roy, Oznur Eroglu, Samuel Strader, William J. Chen, Jeremy N. Kay, Greg D. Field, and Cagla Eroglu. “Thrombospondin-1 Promotes Circuit-Specific Synapse Formation Via β1-Integrin,” December 3, 2019.
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Park, Jieun, Daniel S. Levic, Kaelyn D. Sumigray, Jennifer Bagwell, Oznur Eroglu, Carina L. Block, Cagla Eroglu, et al. “Lysosome-Rich Enterocytes Mediate Protein Absorption in the Vertebrate Gut.” Dev Cell 51, no. 1 (October 7, 2019): 7-20.e6. https://doi.org/10.1016/j.devcel.2019.08.001.Full Text Link to Item
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Sakers, Kristina, and Cagla Eroglu. “Control of neural development and function by glial neuroligins.” Curr Opin Neurobiol 57 (August 2019): 163–70. https://doi.org/10.1016/j.conb.2019.03.007.Full Text Link to Item
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Baldwin, Katherine T., and Cagla Eroglu. “Astrocytes "Chordinate" Synapse Maturation and Plasticity.” Neuron 100, no. 5 (December 5, 2018): 1010–12. https://doi.org/10.1016/j.neuron.2018.11.027.Full Text Link to Item
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Risher, W Christopher, Namsoo Kim, Sehwon Koh, Ji-Eun Choi, Petar Mitev, Erin F. Spence, Louis-Jan Pilaz, et al. “Thrombospondin receptor α2δ-1 promotes synaptogenesis and spinogenesis via postsynaptic Rac1.” J Cell Biol 217, no. 10 (October 1, 2018): 3747–65. https://doi.org/10.1083/jcb.201802057.Full Text Link to Item
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Koh, Sehwon, William J. Chen, Nadine S. Dejneka, Ian R. Harris, Bin Lu, Sergey Girman, Joshua Saylor, Shaomei Wang, and Cagla Eroglu. “Subretinal Human Umbilical Tissue-Derived Cell Transplantation Preserves Retinal Synaptic Connectivity and Attenuates Müller Glial Reactivity.” J Neurosci 38, no. 12 (March 21, 2018): 2923–43. https://doi.org/10.1523/JNEUROSCI.1532-17.2018.Full Text Link to Item
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Liddelow, Shane A., Cagla Eroglu, and Thomas R. Clandinin. “Ben Barres (1954-2017).” Neuron 97, no. 6 (March 21, 2018): 1211–13. https://doi.org/10.1016/j.neuron.2018.03.005.Full Text Link to Item
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“A Tribute to Ben Barres: Remembrances from Barres Lab Members.” Dev Cell 44, no. 4 (February 26, 2018): 415–19. https://doi.org/10.1016/j.devcel.2018.02.011.Full Text Link to Item
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E, Lezi, Ting Zhou, Sehwon Koh, Marian Chuang, Ruchira Sharma, Nathalie Pujol, Andrew D. Chisholm, Cagla Eroglu, Hiroaki Matsunami, and Dong Yan. “An Antimicrobial Peptide and Its Neuronal Receptor Regulate Dendrite Degeneration in Aging and Infection.” Neuron 97, no. 1 (January 3, 2018): 125-138.e5. https://doi.org/10.1016/j.neuron.2017.12.001.Full Text Open Access Copy Link to Item
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Stogsdill, Jeff A., Juan Ramirez, Di Liu, Yong Ho Kim, Katherine T. Baldwin, Eray Enustun, Tiffany Ejikeme, Ru-Rong Ji, and Cagla Eroglu. “Astrocytic neuroligins control astrocyte morphogenesis and synaptogenesis.” Nature 551, no. 7679 (November 8, 2017): 192–97. https://doi.org/10.1038/nature24638.Full Text Link to Item
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Allen, Nicola J., and Cagla Eroglu. “Cell Biology of Astrocyte-Synapse Interactions.” Neuron 96, no. 3 (November 1, 2017): 697–708. https://doi.org/10.1016/j.neuron.2017.09.056.Full Text Link to Item
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Baldwin, Katherine T., and Cagla Eroglu. “Molecular mechanisms of astrocyte-induced synaptogenesis.” Curr Opin Neurobiol 45 (August 2017): 113–20. https://doi.org/10.1016/j.conb.2017.05.006.Full Text Link to Item
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Gomez-Pastor, Rocio, Eileen T. Burchfiel, Daniel W. Neef, Alex M. Jaeger, Elisa Cabiscol, Spencer U. McKinstry, Argenia Doss, et al. “Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington's disease.” Nat Commun 8 (February 13, 2017): 14405. https://doi.org/10.1038/ncomms14405.Full Text Link to Item
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Stogsdill, Jeff A., and Cagla Eroglu. “The interplay between neurons and glia in synapse development and plasticity.” Curr Opin Neurobiol 42 (February 2017): 1–8. https://doi.org/10.1016/j.conb.2016.09.016.Full Text Link to Item
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Park, John, Yanhui Peter Yu, Chun-Yi Zhou, Kang-Wu Li, Dongqing Wang, Eric Chang, Doo-Sik Kim, et al. “Central Mechanisms Mediating Thrombospondin-4-induced Pain States.” J Biol Chem 291, no. 25 (June 17, 2016): 13335–48. https://doi.org/10.1074/jbc.M116.723478.Full Text Link to Item
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Singh, Sandeep K., Jeff A. Stogsdill, Nisha S. Pulimood, Hayley Dingsdale, Yong Ho Kim, Louis-Jan Pilaz, Il Hwan Kim, et al. “Astrocytes Assemble Thalamocortical Synapses by Bridging NRX1α and NL1 via Hevin.” Cell 164, no. 1–2 (January 14, 2016): 183–96. https://doi.org/10.1016/j.cell.2015.11.034.Full Text Link to Item
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Risher, Mary-Louise, Hannah G. Sexton, W Christopher Risher, Wilkie A. Wilson, Rebekah L. Fleming, Roger D. Madison, Scott D. Moore, Cagla Eroglu, and H Scott Swartzwelder. “Adolescent Intermittent Alcohol Exposure: Dysregulation of Thrombospondins and Synapse Formation are Associated with Decreased Neuronal Density in the Adult Hippocampus.” Alcohol Clin Exp Res 39, no. 12 (December 2015): 2403–13. https://doi.org/10.1111/acer.12913.Full Text Link to Item
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Koh, Sehwon, Namsoo Kim, Henry H. Yin, Ian R. Harris, Nadine S. Dejneka, and Cagla Eroglu. “Human Umbilical Tissue-Derived Cells Promote Synapse Formation and Neurite Outgrowth via Thrombospondin Family Proteins.” J Neurosci 35, no. 47 (November 25, 2015): 15649–65. https://doi.org/10.1523/JNEUROSCI.1364-15.2015.Full Text Link to Item
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Risher, Mary-Louise, Rebekah L. Fleming, W Christopher Risher, K. M. Miller, Rebecca C. Klein, Tiffany Wills, Shawn K. Acheson, et al. “Adolescent intermittent alcohol exposure: persistence of structural and functional hippocampal abnormalities into adulthood.” Alcohol Clin Exp Res 39, no. 6 (June 2015): 989–97. https://doi.org/10.1111/acer.12725.Full Text Link to Item
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Chung, Won-Suk, Nicola J. Allen, and Cagla Eroglu. “Astrocytes Control Synapse Formation, Function, and Elimination.” Cold Spring Harb Perspect Biol 7, no. 9 (February 6, 2015): a020370. https://doi.org/10.1101/cshperspect.a020370.Full Text Link to Item
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Risher, W Christopher, Sagar Patel, Il Hwan Kim, Akiyoshi Uezu, Srishti Bhagat, Daniel K. Wilton, Louis-Jan Pilaz, et al. “Astrocytes refine cortical connectivity at dendritic spines.” Elife 3 (December 17, 2014). https://doi.org/10.7554/eLife.04047.Full Text Open Access Copy Link to Item
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McKinstry, Spencer U., Yonca B. Karadeniz, Atesh K. Worthington, Volodya Y. Hayrapetyan, M Ilcim Ozlu, Karol Serafin-Molina, W Christopher Risher, et al. “Huntingtin is required for normal excitatory synapse development in cortical and striatal circuits.” J Neurosci 34, no. 28 (July 9, 2014): 9455–72. https://doi.org/10.1523/JNEUROSCI.4699-13.2014.Full Text Open Access Copy Link to Item
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Wan, Yehong, Kristen K. Ade, Zachary Caffall, M. Ilcim Ozlu, Cagla Eroglu, Guoping Feng, and Nicole Calakos. “Circuit-selective striatal synaptic dysfunction in the Sapap3 knockout mouse model of obsessive-compulsive disorder.” Biol Psychiatry 75, no. 8 (April 15, 2014): 623–30. https://doi.org/10.1016/j.biopsych.2013.01.008.Full Text Link to Item
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Risher, W Christopher, Tuna Ustunkaya, Jonnathan Singh Alvarado, and Cagla Eroglu. “Rapid Golgi analysis method for efficient and unbiased classification of dendritic spines.” Plos One 9, no. 9 (2014): e107591. https://doi.org/10.1371/journal.pone.0107591.Full Text Link to Item
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Singh, Sandeep K., and Cagla Eroglu. “Neuroligins provide molecular links between syndromic and nonsyndromic autism.” Sci Signal 6, no. 283 (July 9, 2013): re4. https://doi.org/10.1126/scisignal.2004102.Full Text Link to Item
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Benner, Eric J., Dominic Luciano, Rebecca Jo, Khadar Abdi, Patricia Paez-Gonzalez, Huaxin Sheng, David S. Warner, Chunlei Liu, Cagla Eroglu, and Chay T. Kuo. “Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4.” Nature 497, no. 7449 (May 16, 2013): 369–73. https://doi.org/10.1038/nature12069.Full Text Open Access Copy Link to Item
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Benner, E. J., D. Luciano, R. Jo, K. Abdi, P. Paez-Gonzalez, H. Sheng, D. S. Warner, C. Liu, C. Eroglu, and C. T. Kuo. “Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4.” Nature 497, no. 7449 (2013): 369–73. https://doi.org/10.1038/nature12069.Full Text Open Access Copy
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Kim, Doo-Sik, Kang-Wu Li, Amin Boroujerdi, Yanhui Peter Yu, Chun-Yi Zhou, Ping Deng, John Park, et al. “Thrombospondin-4 contributes to spinal sensitization and neuropathic pain states.” J Neurosci 32, no. 26 (June 27, 2012): 8977–87. https://doi.org/10.1523/JNEUROSCI.6494-11.2012.Full Text Link to Item
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Risher, W Christopher, and Cagla Eroglu. “Thrombospondins as key regulators of synaptogenesis in the central nervous system.” Matrix Biol 31, no. 3 (April 2012): 170–77. https://doi.org/10.1016/j.matbio.2012.01.004.Full Text Link to Item
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Risher, W., and C. Eroglu. “DISTINCT MORPHOLOGICAL CHANGES IN ASTROCYTES COINCIDE WITH SYNAPTOGENESIS IN THE DEVELOPING SUPERIOR COLLICULUS.” Glia 59 (October 1, 2011): S113–S113.Link to Item
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Kucukdereli, Hakan, Nicola J. Allen, Anthony T. Lee, Ava Feng, M Ilcim Ozlu, Laura M. Conatser, Chandrani Chakraborty, et al. “Control of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARC.” Proc Natl Acad Sci U S A 108, no. 32 (August 9, 2011): E440–49. https://doi.org/10.1073/pnas.1104977108.Full Text Link to Item
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Ippolito, Dominic M., and Cagla Eroglu. “Quantifying synapses: an immunocytochemistry-based assay to quantify synapse number.” J Vis Exp, no. 45 (November 16, 2010). https://doi.org/10.3791/2270.Full Text Link to Item
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Eroglu, Cagla, and Ben A. Barres. “Regulation of synaptic connectivity by glia.” Nature 468, no. 7321 (November 11, 2010): 223–31. https://doi.org/10.1038/nature09612.Full Text Link to Item
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Eroglu, Cagla. “The role of astrocyte-secreted matricellular proteins in central nervous system development and function.” J Cell Commun Signal 3, no. 3–4 (December 2009): 167–76. https://doi.org/10.1007/s12079-009-0078-y.Full Text Link to Item
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Eroglu, Cagla, Nicola J. Allen, Michael W. Susman, Nancy A. O’Rourke, Chan Young Park, Engin Ozkan, Chandrani Chakraborty, et al. “Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis.” Cell 139, no. 2 (October 16, 2009): 380–92. https://doi.org/10.1016/j.cell.2009.09.025.Full Text Link to Item
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Bolton, M McLean, and Cagla Eroglu. “Look who is weaving the neural web: glial control of synapse formation.” Curr Opin Neurobiol 19, no. 5 (October 2009): 491–97. https://doi.org/10.1016/j.conb.2009.09.007.Full Text Link to Item
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Eroglu, C. “HOW DO ASTROCYTES INDUCE CENTRAL NERVOUS SYSTEM SYNAPSE FORMATION?” Journal of Neurochemistry 108 (March 1, 2009): 35–35.Link to Item
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Eroglu, C., B. A. Barres, and B. Stevens. “Glia as active participants in the development and function of synapses,” December 1, 2008, 683–714. https://doi.org/10.1007/978-0-387-77232-5_23.Full Text
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Liauw, Jason, Stanley Hoang, Michael Choi, Cagla Eroglu, Matthew Choi, Guo-hua Sun, Matthew Percy, et al. “Thrombospondins 1 and 2 are necessary for synaptic plasticity and functional recovery after stroke.” J Cereb Blood Flow Metab 28, no. 10 (October 2008): 1722–32. https://doi.org/10.1038/jcbfm.2008.65.Full Text Link to Item
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Weber, Ursula, Cagla Eroglu, and Marek Mlodzik. “Phospholipid membrane composition affects EGF receptor and Notch signaling through effects on endocytosis during Drosophila development.” Dev Cell 5, no. 4 (October 2003): 559–70. https://doi.org/10.1016/s1534-5807(03)00273-9.Full Text Link to Item
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Eroglu, Cagla, Britta Brugger, Felix Wieland, and Irmgard Sinning. “Glutamate-binding affinity of Drosophila metabotropic glutamate receptor is modulated by association with lipid rafts.” Proc Natl Acad Sci U S A 100, no. 18 (September 2, 2003): 10219–24. https://doi.org/10.1073/pnas.1737042100.Full Text Link to Item
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Panneels, Valérie, Cagla Eroglu, Philippe Cronet, and Irmgard Sinning. “Pharmacological characterization and immunoaffinity purification of metabotropic glutamate receptor from Drosophila overexpressed in Sf9 cells.” Protein Expr Purif 30, no. 2 (August 2003): 275–82. https://doi.org/10.1016/s1046-5928(03)00100-1.Full Text Link to Item
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Eroglu, Cagla, Philippe Cronet, Valérie Panneels, Philippe Beaufils, and Irmgard Sinning. “Functional reconstitution of purified metabotropic glutamate receptor expressed in the fly eye.” Embo Rep 3, no. 5 (May 2002): 491–96. https://doi.org/10.1093/embo-reports/kvf088.Full Text Link to Item
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Eroglu, C., E. Yildiz, M. Ozturk, and E. Pinarbasi. “A highly sensitive and specific enzyme-linked immunosorbent assay of antibodies to hepatitis C virus.” Acta Virol 44, no. 1 (February 2000): 29–33.Link to Item
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Book Sections
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Tan, Christabel X., Caley J. Burrus Lane, and Cagla Eroglu. “Role of astrocytes in synapse formation and maturation.,” 142:371–407, 2021. https://doi.org/10.1016/bs.ctdb.2020.12.010.Full Text Link to Item
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Risher, W. C., and C. Eroglu. “Astrocytes and synaptogenesis.” In Synapse Development and Maturation: Comprehensive Developmental Neuroscience, 55–75, 2020. https://doi.org/10.1016/B978-0-12-823672-7.00003-X.Full Text
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Conference Papers
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Eroglu, C. “What are the molecular mechanisms that control astrocyte development in health and disease?” In Glia, 67:E9–E9. WILEY, 2019.Link to Item
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Risher, M. -. L., Q. Li, R. C. Klein, H. G. Sexton, C. E. Eroglu, and D. Moore. “ADOLESCENT INTERMITTENT ETHANOL EXPOSURE: ELUCIDATING THE ROLE OF ASTROCYTES IN THE MODULATION OF NEURONAL FUNCTION.” In Alcoholism Clinical and Experimental Research, 42:334A-334A. WILEY, 2018.Link to Item
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Eroglu, C. “Control of synaptic connectivity by astrocytes.” In Glia, 65:E76–77. WILEY, 2017.Link to Item
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Eroglu, C. “The cell biology of astrocyte-synapse interactions.” In Molecular Biology of the Cell, Vol. 28. AMER SOC CELL BIOLOGY, 2017.Link to Item
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Eroglu, Cagla. “How Do Astrocytes Shape Synaptic Circuits?” In Neuropsychopharmacology, 41:S42–S42. NATURE PUBLISHING GROUP, 2016.Link to Item
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Risher, M. -. L., H. G. Sexton, W. C. Risher, W. A. Wilson, R. L. Fleming, R. D. Madison, S. D. Moore, C. Eroglu, and H. S. Swartzwelder. “ADOLESCENT INTERMITTENT ETHANOL EXPOSURE ALTERS ASTROCYTE SIGNALING IN A RAT MODEL: DYSREGULATION OR ADAPTATION?” In Alcoholism Clinical and Experimental Research, 40:20A-20A. WILEY-BLACKWELL, 2016.Link to Item
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Risher, M. -. L., K. M. Miller, W. C. Risher, S. K. Acheson, R. L. Fleming, R. D. Madison, S. D. Moore, C. Eroglu, and H. S. Swartzwelder. “ENDURING EFFECTS OF REPEATED ADOLESCENT ETHANOL EXPOSURE ON GLIAL-NEURONAL INTERACTIONS AND THE REGULATION OF HIPPOCAMPAL SYNAPTIC ACTIVITY.” In Alcoholism Clinical and Experimental Research, 40:277A-277A. WILEY-BLACKWELL, 2016.Link to Item
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Eroglu, C. “Control of synaptic connectivity and homeostasis by astrocytes.” In Journal of Neurochemistry, 134:43–43. WILEY-BLACKWELL, 2015.Link to Item
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Gunnersen, J., M. Lovric, K. Teng, H. Daykin, C. Wright, J. Barwood, C. Eroglu, and B. Graham. “SEZ6 binds the analgesic target alpha 2 delta and contributes to neuropathic pain plasticity.” In Journal of Neurochemistry, 134:141–141. WILEY-BLACKWELL, 2015.Link to Item
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Koh, Sehwon, Namsoo Kim, Nadine S. Dejneka, Ian R. Harris, Henry H. Yin, and Cagla Eroglu. “Human umbilical tissue-derived cells (hUTC) promote synapse formation and neurite outgrowth via Thrombospondin family proteins: A potential mechanism for hUTC-based therapy in retinal-degenerative diseases.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Eroglu, C. “Astrocyes orchestrate dendritic spine formation and maturation.” In Journal of Neurochemistry, 125:29–29. WILEY-BLACKWELL, 2013.Link to Item
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Singh, S. K., A. Pamukcu, and C. Eroglu. “How do astrocyte secreted factors Hevin and SPARC control excitatory synaptogenesis in the CNS?” In Journal of Neurochemistry, 125:8–8. WILEY-BLACKWELL, 2013.Link to Item
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- Teaching & Mentoring
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Recent Courses
- CELLBIO 493: Research Independent Study 2023
- NEUROSCI 494: Research Independent Study 2 2023
- NEUROSCI 495: Research Independent Study 3 2023
- CELLBIO 493: Research Independent Study 2022
- NEUROSCI 493: Research Independent Study 1 2022
- NEUROSCI 494: Research Independent Study 2 2022
- CELLBIO 493: Research Independent Study 2021
- NEUROBIO 393: Research Independent Study 2021
- NEUROBIO 793: Research in Neurobiology 2021
- NEUROSCI 493: Research Independent Study 1 2021
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Advising & Mentoring
Available to mentor:
- PhD
- Post-Doc
- Undergraduate
- Scholarly, Clinical, & Service Activities
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Outreach & Engaged Scholarship
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