Li-Tzy Wu
Professor in Psychiatry and Behavioral Sciences

Education/Training: Pre- and post-doctoral training in mental health service research, psychiatric epidemiology (NIMH T32), and addiction epidemiology (NIDA T32) from Johns Hopkins University School of Public Health (Maryland); Fellow of the NIH Summer Institute on the Design and Conduct of Randomized Clinical Trials.

Node Principal Investigator and Director: Mid Southern (Primary Care Networks) Node, NIDA National Drug Abuse Treatment Clinical Trials Network.

Research interests: Opioid misuse, Opioid use disorder, Polysubstance use, cannabis, alcohol, tobacco,  stimulants, SBIRT, EHR-based research and intervention, data science, psychometric analysis (IRT), epidemiology of addictions and comorbidity, behavioral health integration, utilization of mental health and substance use treatments and outcomes, diagnostic validity, nosology, research design/methods, HIV risk behavior. 

FUNDED Research projects (Principal Investigator, PI): 
Substance use/dependence (R03).
Treatment use for alcohol use disorders (R21).
Inhalant use & disorders (R21).
MDMA/hallucinogen use/disorders (R01).
Prescription opioid misuse/use disorders (R01).
Substance use disorders in adolescents (R01).
Substance use diagnoses & treatment (R21, R33).
Evolution of Psychopathology in the Population (R01: ECA Duke site PI).
Substance use disorders and treatment use among Asian Americans and Pacific Islanders (R01).
SBIRT-Primary Care (UG1: SBIRT, NIDA Clinical Trials Network).
Substance use screening tool validation in primary care (UG1: TAPS Tool, NIDA Clinical Trials Network).
Computer-facilitated intervention for adolescent marijuana use prevention (UG1: CAMP, NIDA CTN).
NIDA CTN Mid Southern Node (UG1: NIDA Clinical Trials Network).
EHR Data Element Study (UG1: EHR-DARE, NIDA Clinical Trials Network).
Pharmacy Opioid Use Disorder Care (UG1: CTN-0075, NIDA Clinical Trials Network).
INSPIRE: Integrated Health Services to Reduce Opioid Use While Managing Chronic Pain (PCORI: Duke Site PI).
Evaluation of state-mandated acute and post-surgical pain-specific CDC opioid prescribing (R01: Duke Site PI).
Measuring Opioid Use Disorders in Secondary Electronic Health Records Data (Carolinas Collaborative/CTSA: Duke Site PI).
Developing a prevention model of alcohol use disorder for Pacific Islander young adults (R21: Duke Site PI).

Committee member of the NIDA Asian American and Pacific Islander Researchers and Scholars Workgroup (NIDA AAPI Workgroup).




Office Hours

By appointment

Current Appointments & Affiliations

Contact Information

  • Duke South Hospital, Rm 3521, Box 3903, Durham, NC 27710
  • Duke University Medical Center, Psychiatry Box 3903, Durham, NC 27710
  • uri icon Psychiatry Profile

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