Li-Tzy Wu

Journal Article Addict Sci Clin Pract · December 2, 2024 BACKGROUND: Pharmacists play a key role in combating the opioid-related overdose epidemic in the United States (US), but little is known about their experience and willingness to deliver preventive services for opioid use disorder (OUD). AIMS: This study s ... Full text Link to item Cite

Long-term Risk of Serious Infections and Mortality Among Patients Surviving Drug Use-Associated Infective Endocarditis.

Journal Article Clin Infect Dis · July 19, 2024 Featured Publication Among a statewide cohort of 1874 patients surviving hospitalization for drug use-associated endocarditis during 2017-2020, the 3-year risk of death or future hospitalization was 38% (16% for death before later infection, 14% for recurrent endocarditis, 14% ... Full text Open Access Link to item Cite

Long-Term Mortality After Drug Use-Associated Endocarditis is High and Differs by Race and Sex: Results of a Statewide Study

Conference Drug and Alcohol Dependence · July 2024 Featured Publication Full text Cite

Tools to implement measurement-based care (MBC) in the treatment of opioid use disorder (OUD): toward a consensus.

Journal Article Addict Sci Clin Pract · February 28, 2024 Featured Publication BACKGROUND: The prevalence and associated overdose death rates from opioid use disorder (OUD) have dramatically increased in the last decade. Despite more available treatments than 20 years ago, treatment access and high discontinuation rates are challenge ... Full text Open Access Link to item Cite

Design of a Multicenter Randomized Controlled Trial comparing the effectiveness of shared decision making versus motivational interviewing plus cognitive behavioral therapy for voluntary opioid tapering: The INSPIRE study protocol.

Journal Article Contemp Clin Trials · February 2024 Featured Publication BACKGROUND: This paper describes the design and protocol of a pragmatic, randomized trial to evaluate the comparative effectiveness of shared decision making versus motivational interviewing plus cognitive behavioral therapy for chronic pain for the volunt ... Full text Open Access Link to item Cite

Performance of the Tobacco, Alcohol, Prescription Medication, and Other Substance Use (TAPS) Tool in Screening Older Adults for Unhealthy Substance Use

Journal Article Journal of Addiction Medicine · January 1, 2024 Featured Publication Objective: This analysis evaluated the validation results of the Tobacco, Alcohol, Prescription Medication, and Other Substance Use (TAPS) tool for older adults. Methods: We performed a subgroup analysis of older adults aged ≥65 (n = 184) from the TAPS too ... Full text Open Access Cite

Subthreshold opioid use disorder prevention (STOP) trial: a cluster randomized clinical trial: study design and methods.

Journal Article Addict Sci Clin Pract · November 18, 2023 Featured Publication BACKGROUND: Preventing progression to moderate or severe opioid use disorder (OUD) among people who exhibit risky opioid use behavior that does not meet criteria for treatment with opioid agonists or antagonists (subthreshold OUD) is poorly understood. The ... Full text Open Access Link to item Cite

Research Priorities for Expansion of Opioid Use Disorder Treatment in the Community Pharmacy.

Journal Article Subst Abus · October 2023 Featured Publication In the last decade, the U.S. opioid overdose crisis has magnified, particularly since the introduction of synthetic opioids, including fentanyl. Despite the benefits of medications for opioid use disorder (MOUD), only about a fifth of people with opioid us ... Full text Open Access Link to item Cite

Pharmacy-based methadone treatment in the US: views of pharmacists and opioid treatment program staff.

Journal Article Subst Abuse Treat Prev Policy · September 11, 2023 Featured Publication BACKGROUND: The US federal regulations allow pharmacy administration and dispensing of methadone for opioid use disorder (PADMOUD) to increase the capability of opioid treatment programs (OTPs) in providing methadone maintenance treatment (MMT) for opioid ... Full text Open Access Link to item Cite

Patient perspectives on community pharmacy administered and dispensing of methadone treatment for opioid use disorder: a qualitative study in the U.S.

Journal Article Addict Sci Clin Pract · August 2, 2023 Featured Publication BACKGROUND: Pharmacy administration and dispensing of methadone treatment for opioid use disorder (PADMOUD) may address inadequate capability of opioid treatment programs (OTPs) in the US by expanding access to methadone at community pharmacies nationally. ... Full text Open Access Link to item Cite

A Brief Screening and Assessment Tool for Opioid Use in Adults: Results from a Validation Study of the Tobacco, Alcohol, Prescription Medication, and Other Substances Tool.

Journal Article J Addict Med · July 2023 Featured Publication OBJECTIVES: This secondary analysis evaluated opioid-specific validation results of the Tobacco, Alcohol, Prescription Medication, and Other Substances (TAPS) tool for screening in primary care. METHODS: This study is a secondary data analysis of the TAPS ... Full text Open Access Link to item Cite

The Impact of Discharge Against Medical Advice on Readmission After Opioid Use Disorder-Associated Infective Endocarditis: a National Cohort Study.

Journal Article J Gen Intern Med · May 2023 Featured Publication BACKGROUND: Hospitalizations for infective endocarditis (IE) associated with opioid use disorder (O-IE) have increased in the USA and have been linked to high rates of discharge against medical advice (DAMA). DAMA represents a truncation of care for a seve ... Full text Open Access Link to item Cite

Development and validation of an electronic health records-based opioid use disorder algorithm by expert clinical adjudication among patients with prescribed opioids.

Journal Article Pharmacoepidemiol Drug Saf · May 2023 Featured Publication BACKGROUND: In the US, over 200 lives are lost from opioid overdoses each day. Accurate and prompt diagnosis of opioid use disorders (OUD) may help prevent overdose deaths. However, international classification of disease (ICD) codes for OUD are known to u ... Full text Open Access Link to item Cite

A Brief Screening and Assessment Tool for Opioid Use in Adults: Results from a Validation Study of the Tobacco, Alcohol, Prescription Medication, and Other Substances Tool.

Journal Article J Addict Med · February 6, 2023 Featured Publication OBJECTIVES: This secondary analysis evaluated opioid-specific validation results of the Tobacco, Alcohol, Prescription Medication, and Other Substances (TAPS) tool for screening in primary care. METHODS: This study is a secondary data analysis of the TAPS ... Full text Open Access Link to item Cite

Assessing the Impact of COVID-19 on the Health of Native Hawaiian/Pacific Islander People in the United States, 2021.

Journal Article Public Health Rep · 2023 Featured Publication OBJECTIVES: Minimal research has assessed COVID-19's unique impact on the Native Hawaiian/Pacific Islander (NH/PI) population-an Indigenous-colonized racial group with social and health disparities that increase their risk for COVID-19 morbidity and mortal ... Full text Open Access Link to item Cite

Native Hawaiian/Pacific Islander alcohol, tobacco and other drug use, mental health and treatment need in the United States during COVID-19.

Journal Article Drug Alcohol Rev · November 2022 Featured Publication INTRODUCTION: Before COVID-19, Native Hawaiians/Pacific Islanders (NH/PI) endured a heavy burden of alcohol, tobacco and other drug (ATOD) use in prior US data. Responding to reports that many NH/PI communities experienced severe COVID-19 disparities that ... Full text Open Access Link to item Cite

Alcohol Use Disorder Risk and Protective Factors and Associated Harms Among Pacific Islander Young Adults.

Journal Article J Racial Ethn Health Disparities · October 2022 Featured Publication Pacific Islander (PI) young adults (age 18 to 30 years) experience elevated rates of hazardous drinking, AUDs, and alcohol-related harms. Yet, we know little about the risk and protective factors that drive, or can prevent, PI young adult hazardous drinkin ... Full text Open Access Link to item Cite

The opioid use disorder core outcomes set (OUD-COS) for treatment research: findings from a Delphi consensus study.

Journal Article Addiction · September 2022 Featured Publication BACKGROUND AND AIM: There is no gold-standard and considerable heterogeneity in outcome measures used to evaluate treatments for opioid use disorder (OUD) along the opioid treatment cascade. The aim of this study was to develop the US National Institute on ... Full text Open Access Link to item Cite

Mifepristone (RU-486®) as a Schedule IV Controlled Drug-Implications for a Misleading Drug Policy on Women's Health Care.

Journal Article Int J Environ Res Public Health · July 8, 2022 Featured Publication BACKGROUND: Mifepristone (RU-486) has been approved for abortion in Taiwan since 2000. Mifepristone was the first non-addictive medicine to be classified as a schedule IV controlled drug. As a case of the "misuse" of "misuse of drugs laws," the policy and ... Full text Open Access Link to item Cite

Opioid treatment program prescribing of methadone with community pharmacy dispensing: Pilot study of feasibility and acceptability.

Journal Article Drug Alcohol Depend Rep · June 2022 Featured Publication Access to methadone for opioid use disorder (OUD) in the United States remains limited to regulated and certified Opioid Treatment Programs (OTPs). Collaboration between OTPs and community pharmacies would increase access to and potentially satisfaction wi ... Full text Open Access Link to item Cite

Association of chronic non-cancer pain status and buprenorphine treatment retention among individuals with opioid use disorder: Results from electronic health record data.

Journal Article Drug Alcohol Depend Rep · June 2022 Featured Publication BACKGROUND: Although chronic non-cancer pain (CNCP) is common among individuals with opioid use disorder (OUD), its impact on buprenorphine treatment retention is unclear. The goal of this study was to use electronic health record (EHR) data to examine the ... Full text Open Access Link to item Cite

Opioid treatment program and community pharmacy collaboration for methadone maintenance treatment: results from a feasibility clinical trial.

Journal Article Addiction (Abingdon, England) · February 2022 Featured Publication Background and aimsPharmacy administration and dispensing of methadone for methadone maintenance treatment (MMT) can expand treatment access for opioid use disorder (OUD). This study investigated the feasibility and acceptability of a novel model ... Full text Open Access Cite

Implementation of mandatory opioid prescribing limits in North Carolina: healthcare administrator and prescriber perspectives.

Journal Article BMC Health Serv Res · November 3, 2021 Featured Publication BACKGROUND: Recent increases in state laws to reduce opioid prescribing have demonstrated a need to understand how they are interpreted and implemented in healthcare systems. The purpose of this study was to explore the systems, strategies, and resources t ... Full text Open Access Link to item Cite

Buprenorphine physician-pharmacist collaboration in the management of patients with opioid use disorder: results from a multisite study of the National Drug Abuse Treatment Clinical Trials Network.

Journal Article Addiction · July 2021 Featured Publication BACKGROUND AND AIMS: Physician and pharmacist collaboration may help address the shortage of buprenorphine-waivered physicians and improve care for patients with opioid use disorder (OUD). This study investigated the feasibility and acceptability of a new ... Full text Open Access Link to item Cite

0108 Limitations of opioid use disorder (OUD) ICD codes: development and validation of a new OUD identification algorithm in electronic medical records

Conference Abstracts · April 2021 Featured Publication Full text Cite

Predictive model of multiple emergency department visits among adults: analysis of the data from the National Survey of Drug Use and Health (NSDUH).

Journal Article BMC Health Serv Res · March 25, 2021 Featured Publication BACKGROUND: In this methodological paper, we use a novel, predictive approach to examine how demographics, substance use, mental and other health indicators predict multiple visits (≥3) to emergency departments (ED) within a year. METHODS: State-of-the-art ... Full text Open Access Link to item Cite

Comorbid Substance Use Disorder Profiles and Receipt of Substance Use Disorder Treatment Services: A National Study.

Journal Article J Stud Alcohol Drugs · March 2021 Featured Publication OBJECTIVE: Those with comorbid substance use disorders (SUDs) are a particularly vulnerable group. Information regarding the nature of these comorbidities and how they relate to receipt of substance use treatment could reduce the treatment gap that exists ... Full text Open Access Link to item Cite

Core outcomes set for research on the treatment of opioid use disorder (COS-OUD): the National Institute on Drug Abuse Clinical Trials Network protocol for an e-Delphi consensus study.

Journal Article Trials · January 28, 2021 Featured Publication BACKGROUND: A lack of consensus on the optimal outcome measures to assess the efficacy and effectiveness of interventions for the treatment of opioid use disorder (OUD) has hampered the pooling of research data for evidence synthesis and clinical guideline ... Full text Open Access Link to item Cite

Recent and active problematic substance use among primary care patients: Results from the alcohol, smoking, and substance involvement screening test in a multisite study.

Journal Article Subst Abus · 2021 Featured Publication Background: Primary care settings provide salient opportunities for identifying patients with problematic substance use and addressing unmet treatment need. The aim of this study was to examine the extent and correlates of problematic substance use by subs ... Full text Open Access Link to item Cite

Research priorities for expanding access to methadone treatment for opioid use disorder in the United States: A National Institute on Drug Abuse Center for Clinical Trials Network Task Force report.

Journal Article Subst Abus · 2021 Featured Publication In the US, methadone treatment can only be provided to patients with opioid use disorder (OUD) through federal and state-regulated opioid treatment programs (OTPs). There is a shortage of OTPs, and racial and geographic inequities exist in access to methad ... Full text Open Access Link to item Cite

Substance Use and Misuse in Older Adults: A Need for Research and Intervention

Journal Article The Gerontologist · August 14, 2020 Featured Publication Full text Open Access Cite

Multiple drug use disorder diagnoses among drug-involved hospitalizations in the United States: Results from the 2016 National Inpatient Sample.

Journal Article Drug Alcohol Depend · August 1, 2020 Featured Publication BACKGROUND: Having more than one drug use disorders (DUDs) is an increasing public health concern, but it has been understudied. The goal of this study is to investigate the prevalence and patterns of coexisting DUD diagnoses among inpatient hospitalizatio ... Full text Open Access Link to item Cite

Prevalence and Health Characteristics of Prescription Opioid Use, Misuse, and Use Disorders Among U.S. Adolescents.

Journal Article J Adolesc Health · May 2020 Featured Publication PURPOSE: The prevalence of past-year prescription opioid use (POU), nonmedical POU (NMPOU), and POU disorder (POUD) and their correlates were examined in a national sample of American adolescents (N = 41,579). METHODS: This study used data from the public- ... Full text Open Access Link to item Cite

Chronic non-cancer pain among adults with substance use disorders: Prevalence, characteristics, and association with opioid overdose and healthcare utilization.

Journal Article Drug Alcohol Depend · April 1, 2020 Featured Publication BACKGROUND: Chronic non-cancer pain (CNCP) among patients with substance use disorder (SUD) poses a risk for worse treatment outcomes. Understanding the association of CNCP with SUD is important for informing the need and potential benefits of pain assessm ... Full text Open Access Link to item Cite

Comparison of timeline follow-back self-report and oral fluid testing to detect substance use in adult primary care patients.

Journal Article Drug Alcohol Depend · April 1, 2020 Featured Publication BACKGROUND: Timeline Follow-back (TLFB) interviews using self-report are often used to assess substance use. Oral fluid testing (OFT) offers an objective measure of substance use. There are limited data on the agreement between TLFB and OFT. METHODS: In th ... Full text Open Access Link to item Cite

Using a health information technology survey to explore the availability of addiction treatment data in the electronic health records: A National Drug Abuse Treatment Clinical Trials Network study.

Journal Article J Subst Abuse Treat · March 2020 Featured Publication BACKGROUND: Healthcare data from electronic health records (EHRs) and related health information technology (IT) tools are critical data sources for pragmatic clinical trials and observational studies aimed at producing real-world evidence. To unlock the f ... Full text Open Access Link to item Cite

E-Cigarette Use Among Adult Primary Care Patients: Results from a Multisite Study.

Journal Article J Gen Intern Med · January 2020 Featured Publication BACKGROUND: Primary care settings provide opportunities to identify electronic-cigarette (e-cigarette) use and to implement strategies for changing tobacco use behavior. However, a better understanding of the extent and associated characteristics of e-ciga ... Full text Open Access Link to item Cite

Sources of Misused Prescription Opioids and Their Association with Prescription Opioid Use Disorder in the United States: Sex and Age Differences.

Journal Article Subst Use Misuse · 2020 Featured Publication Background: Prescription opioid (PO) misuse and prescription opioid use disorder (POUD) are a national crisis in the USA. To inform strategies for reducing the PO epidemic, research is needed on the sources of misused POs and their association with POUD. M ... Full text Open Access Link to item Cite

Electronic Cigarette Use and Associated Risk Factors in U.S.-Dwelling Pacific Islander Young Adults.

Journal Article Subst Use Misuse · 2020 Featured Publication Background: E-cigarette use is rapidly increasing among US young adults, heightening their risk for vaping-related illnesses. Yet, little is known about e-cigarette use among young adult Native Hawaiians and Pacific Islanders (NHPI): an indigenous-colonize ... Full text Open Access Link to item Cite

Hazardous drinking, alcohol use disorders, and need for treatment among Pacific Islander young adults.

Journal Article Am J Orthopsychiatry · 2020 Featured Publication Pacific Islander (PI) young adults are suspected to bear heavy risk for hazardous drinking, alcohol use disorders (AUD), and alcohol-related harms. Yet, PIs remain among the most understudied racial groups in the United States-creating a lack of empirical ... Full text Open Access Link to item Cite

Electronic self-administered screening for substance use in adult primary care patients: feasibility and acceptability of the tobacco, alcohol, prescription medication, and other substance use (myTAPS) screening tool.

Journal Article Addict Sci Clin Pract · October 15, 2019 Featured Publication BACKGROUND: The TAPS Tool is a substance use screening and brief assessment instrument that was developed for use in primary care medical settings. It is one of the first screening instruments to provide rapid assessment of all commonly used substance clas ... Full text Open Access Link to item Cite

Commentary on Winhusen et al. (2019): Substance use disorders, chronic diseases, and electronic health records-a paradigm for screening and intervention.

Journal Article Addiction · August 2019 Featured Publication The use of the electronic health record to study the relationship between substance use disorders, diabetes and hypertension has identified high-severity, high-cost conditions. Improving data quality and validation will enhance our ability to perform medic ... Full text Open Access Link to item Cite

Clinical Workflow and Substance Use Screening, Brief Intervention, and Referral to Treatment Data in the Electronic Health Records: A National Drug Abuse Treatment Clinical Trials Network Study.

Journal Article EGEMS (Wash DC) · August 1, 2019 Featured Publication INTRODUCTION: The use of electronic health records (EHR) data in research to inform recruitment and outcomes is considered a critical element for pragmatic studies. However, there is a lack of research on the availability of substance use disorder (SUD) tr ... Full text Open Access Link to item Cite

Relationship between Smoking and Abdominal Aorta Calcification on Computed Tomography.

Journal Article Korean J Fam Med · July 2019 Featured Publication BACKGROUND: Cigarette smoking increases the risk of atherosclerosis, which often develops as vascular calcification on radiologic examinations. This study evaluated the relationship between smoking-related factors and incidental abdominal aorta calcificati ... Full text Open Access Link to item Cite

Trends and correlates of driving under the influence of alcohol among different types of adult substance users in the United States: a national survey study.

Journal Article BMC Public Health · May 4, 2019 Featured Publication BACKGROUND: Despite a decrease in driving under the influence of alcohol (DUIA) prevalence over the past decades, DUIA prevalence still remains high in the United States. To date, there is limited research examining whether different types of substance use ... Full text Open Access Link to item Cite

Discharge against medical advice from hospitalizations for substance use disorders: The potential impact of the Affordable Care Act.

Journal Article Drug Alcohol Depend · April 1, 2019 Featured Publication OBJECTIVES: To explore whether the Affordable Care Act (ACA) enactment is associated with changes in the proportion of discharge against medical advice (DAMA) among hospitalizations due to substance use disorders (SUDs). METHODS: Data were drawn from the 2 ... Full text Open Access Link to item Cite

Clinical epidemiology of substance use disorders: Understanding patterns, sharing knowledge, planning interventions.

Journal Article Indian J Med Res · April 2019 Featured Publication Full text Open Access Link to item Cite

Interpretation and integration of the federal substance use privacy protection rule in integrated health systems: A qualitative analysis.

Journal Article J Subst Abuse Treat · February 2019 Featured Publication BACKGROUND: Federal regulations (42 CFR Part 2) provide special privacy protections for persons seeking treatment for substance use disorders. Primary care providers, hospitals, and health care organizations have struggled to balance best practices for med ... Full text Open Access Link to item Cite

Trends in Drug Use-Associated Infective Endocarditis and Heart Valve Surgery, 2007 to 2017: A Study of Statewide Discharge Data.

Journal Article Ann Intern Med · January 1, 2019 Featured Publication BACKGROUND: Drug use-associated infective endocarditis (DUA-IE) is increasing as a result of the opioid epidemic. Infective endocarditis may require valve surgery, but surgical treatment of DUA-IE has invoked controversy, and the extent of its use is unkno ... Full text Open Access Link to item Cite

Prevalence and patterns of opioid misuse and opioid use disorder among primary care patients who use tobacco.

Journal Article Drug Alcohol Depend · January 1, 2019 Featured Publication BACKGROUND: Current data suggest that opioid misuse or opioid use disorder (OUD) may be over represented among tobacco users. However, this association remains understudied in primary care settings. A better understanding of the extent of heterogeneity in ... Full text Open Access Link to item Cite

Sex differences in the prevalence and correlates of emergency department utilization among adults with prescription opioid use disorder.

Journal Article Subst Use Misuse · 2019 Featured Publication BACKGROUND: The emergency department (ED) is well-suited as an opportunity to increase treatment access for prescription opioid use disorder (POUD). We examined sex differences in ED utilization among individuals with POUD to understand potential sex-speci ... Full text Open Access Link to item Cite

Opioid use disorder deaths and the effects of medication therapy.

Journal Article Am J Drug Alcohol Abuse · 2019 Featured Publication Full text Open Access Link to item Cite

Pharmacists' attitudes toward dispensing naloxone and medications for opioid use disorder: A scoping review of the literature.

Journal Article Subst Abus · 2019 Featured Publication Background: Pharmacists are on the frontline caring for patients at risk of an opioid overdose and for patients with an opioid use disorder (OUD). Dispensing naloxone and medications for OUD and counseling patients about these medications are ways pharmaci ... Full text Open Access Link to item Cite

Readmission After Discharge Against Medical Advice for Persons With Opioid-Associated Infective Endocarditis

Conference CIRCULATION · 2019 Featured Publication Open Access Cite

Multicomorbidity of chronic diseases and substance use disorders and their association with hospitalization: Results from electronic health records data.

Journal Article Drug Alcohol Depend · November 1, 2018 Featured Publication BACKGROUND: Chronic diseases are prevalent and the leading causes of mortality. Comorbidity of substance use disorders (SUDs) and chronic diseases is understudied to inform behavioral healthcare integration. OBJECTIVES: This study leveraged electronic heal ... Full text Open Access Link to item Cite

Withdrawal severity and early response to treatment in the outpatient transition from opioid use to extended release naltrexone.

Journal Article Am J Addict · September 2018 Featured Publication BACKGROUND AND OBJECTIVES: Long acting naltrexone has improved the therapy of opioid use disorder (OUD), and safe and effective withdrawal management during naltrexone induction may help advance treatment. Despite the uncertain role of opioid withdrawal in ... Full text Open Access Link to item Cite

National trends and characteristics of inpatient detoxification for drug use disorders in the United States.

Journal Article BMC Public Health · August 29, 2018 Featured Publication BACKGROUND: Prior studies indicate that the opportunity from detoxification to engage in subsequent drug use disorder (DUD) treatment may be missed. This study examined national trends and characteristics of inpatient detoxification for DUDs and explored f ... Full text Open Access Link to item Cite

Prevalence, patterns, and correlates of multiple substance use disorders among adult primary care patients.

Journal Article Drug Alcohol Depend · June 1, 2018 Featured Publication BACKGROUND: Addressing multiple substance use disorders (SUDs) in primary care-based screening and intervention may improve SUD treatment access, engagement, and outcomes. To inform such efforts, research is needed on the prevalence and patterns of multipl ... Full text Open Access Link to item Cite

Substance Use and Suicide in Pacific Islander, American Indian, and Multiracial Youth.

Journal Article Am J Prev Med · June 2018 Featured Publication INTRODUCTION: National estimates of U.S. Native Hawaiian and other Pacific Islander (NHPI), American Indian/Alaskan Native (AIAN), and multiracial adolescent substance use and suicidality are scarce because of their small population sizes. The aim was to e ... Full text Open Access Link to item Cite

Substance use disorders and medical comorbidities among high-need, high-risk patients with diabetes.

Journal Article Drug Alcohol Depend · May 1, 2018 Featured Publication BACKGROUND: The majority of the U.S. healthcare resources are utilized by a small population characterized as high-risk, high-need persons with complex care needs (e.g., adults with multiple chronic conditions). Substance use disorders (SUDs) and mental he ... Full text Open Access Link to item Cite

Trends and correlates of cocaine use and cocaine use disorder in the United States from 2011 to 2015.

Journal Article Drug Alcohol Depend · November 1, 2017 Featured Publication BACKGROUND: Recent epidemiological data suggest a resurgence in cocaine use (CU) and cocaine-related problems in the United States. Demographic trends and correlates of problem CU are needed to determine potential factors that may be influencing the increa ... Full text Open Access Link to item Cite

Differences in behavioral health disorders and unmet treatment needs between medical marijuana users and recreational marijuana users: Results from a national adult sample.

Journal Article Drug Alcohol Depend · November 1, 2017 Featured Publication BACKGROUND: Available data suggest that medical marijuana users may have more mental health problems than recreational marijuana users. There is limited information about differences in behavioral health disorders and unmet treatment needs between medical ... Full text Open Access Link to item Cite

DSM-5 substance use disorders among adult primary care patients: Results from a multisite study.

Journal Article Drug Alcohol Depend · October 1, 2017 Featured Publication BACKGROUND: There are limited data about the extent of DSM-5 substance use disorders (SUDs) among primary care patients. METHODS: This study analyzed data from a multisite validation study of a substance use screening instrument conducted in a diverse samp ... Full text Open Access Link to item Cite

Validation of the TAPS-1: A Four-Item Screening Tool to Identify Unhealthy Substance Use in Primary Care.

Journal Article J Gen Intern Med · September 2017 Featured Publication BACKGROUND: The Tobacco, Alcohol, Prescription Medication, and Other Substance use (TAPS) tool is a combined two-part screening and brief assessment developed for adult primary care patients. The tool's first-stage screening component (TAPS-1) consists of ... Full text Open Access Link to item Cite

Problem alcohol use and healthcare utilization among persons with cannabis use disorder in the United States.

Journal Article Drug Alcohol Depend · September 1, 2017 Featured Publication BACKGROUND: The emergency department (ED) and hospital settings represent crucial opportunities for engaging treatment for cannabis use disorder (CUD). Thus, there is a need to identify factors associated with healthcare utilization among persons with CUD ... Full text Open Access Link to item Cite

Prevalence, reasons, perceived effects, and correlates of medical marijuana use: A review.

Journal Article Drug Alcohol Depend · August 1, 2017 Featured Publication BACKGROUND: The use of marijuana for medical purposes is now legal in some U.S. states and other jurisdictions, such as Canada, and Israel. Despite the widespread legalization of medical marijuana globally, there is limited information on patterns and corr ... Full text Open Access Link to item Cite

Prevalence and correlates of treatment utilization among adults with cannabis use disorder in the United States.

Journal Article Drug Alcohol Depend · August 1, 2017 Featured Publication BACKGROUND: The increase in cannabis potency may have treatment implications for cannabis use disorder (CUD). Given the reported increase in prevalence of cannabis use among adults, there is a need to understand substance use treatment needs for CUD. METHO ... Full text Open Access Link to item Cite

Age of first drunkenness and risks for all-cause mortality: A 27-year follow-up from the epidemiologic catchment area study.

Journal Article Drug Alcohol Depend · July 1, 2017 Featured Publication BACKGROUND: Early-onset drunkenness is associated with an increased risk of developing an alcohol use disorder (AUD), which predicts excess mortality risk. Here, we estimated mortality risk for drinkers with and without early drunkenness. METHODS: For 14,8 ... Full text Open Access Link to item Cite

Identifying substance misuse in primary care: TAPS Tool compared to the WHO ASSIST.

Journal Article J Subst Abuse Treat · May 2017 Featured Publication BACKGROUND: There is a need for screening and brief assessment instruments to identify primary care patients with substance use problems. This study's aim was to examine the performance of a two-step screening and brief assessment instrument, the TAPS Tool ... Full text Open Access Link to item Cite

VALIDATION OF THE 4-ITEM SCREENING COMPONENT OF THE TAPS TOOL TO IDENTIFY UNHEALTHY SUBSTANCE USE AMONG PRIMARY CARE PATIENTS

Conference JOURNAL OF GENERAL INTERNAL MEDICINE · April 1, 2017 Featured Publication Open Access Link to item Cite

Using electronic health records data for clinical research

Conference Drug and Alcohol Dependence · February 2017 Featured Publication Full text Cite

A brief substance use screening and assessment for general medical settings: Validation of the tobacco, alcohol, prescription medication, and other substance use tool

Conference Drug and Alcohol Dependence · February 2017 Featured Publication Full text Cite

Marijuana use and sex with multiple partners among lesbian, gay and bisexual youth: results from a national sample.

Journal Article BMC Public Health · January 5, 2017 Featured Publication BACKGROUND: Sex with multiple partners (SMP) is one of the important contributing factors for contracting sexually transmitted infections (STIs) among adolescents and young adults, especially among Lesbian, Gay, and Bisexual (LGB) youth. Past studies mainl ... Full text Open Access Link to item Cite

Sex Differences in Cannabis Use Disorder Diagnosis Involved Hospitalizations in the United States.

Journal Article J Addict Med · 2017 Featured Publication OBJECTIVES: The study examined sex differences in trend and clinical characteristics of cannabis use disorder (CUD) diagnosis involved hospitalizations among adult patients. METHODS: We analyzed hospitalization data from the 2007-2011 Nationwide Inpatient ... Full text Open Access Link to item Cite

The opioid overdose epidemic: opportunities for pharmacists.

Journal Article Subst Abuse Rehabil · 2017 Featured Publication Full text Open Access Link to item Cite

Treatment utilization among persons with opioid use disorder in the United States.

Journal Article Drug Alcohol Depend · December 1, 2016 Featured Publication BACKGROUND: The United States is experiencing an opioid overdose epidemic. Treatment use data from diverse racial/ethnic groups with opioid use disorder (OUD) are needed to inform treatment expansion efforts. METHODS: We examined demographic characteristic ... Full text Open Access Link to item Cite

Performance of the Tobacco, Alcohol, Prescription Medication, and Other Substance Use (TAPS) Tool for Substance Use Screening in Primary Care Patients.

Journal Article Ann Intern Med · November 15, 2016 Featured Publication BACKGROUND: Substance use, a leading cause of illness and death, is underidentified in medical practice. OBJECTIVE: The Tobacco, Alcohol, Prescription medication, and other Substance use (TAPS) tool was developed to address the need for a brief screening a ... Full text Open Access Link to item Cite

Corrigendum to "Design of the NIDA clinical trials network validation study of tobacco, alcohol, prescription medications, and substance use/misuse (TAPS) tool" [Contemporary Clinical Trials. 2016 Jul. 19; 50: 90-97].

Journal Article Contemp Clin Trials · November 2016 Featured Publication Full text Open Access Link to item Cite

Proceedings of the 13th annual conference of INEBRIA.

Journal Article Addict Sci Clin Pract · September 19, 2016 Featured Publication Full text Open Access Link to item Cite

The Association of Gasoline Prices With Hospital Utilization and Costs for Motorcycle and Nonmotorcycle Motor Vehicle Injuries in the United States.

Journal Article Med Care · September 2016 Featured Publication OBJECTIVES: This study examined the association between gasoline prices and hospitalizations for motorcycle and nonmotorcycle motor vehicle crash (MVC) injuries. METHODS: Data on inpatient hospitalizations were obtained from the 2001 to 2010 Nationwide Inp ... Full text Open Access Link to item Cite

Design of the NIDA clinical trials network validation study of tobacco, alcohol, prescription medications, and substance use/misuse (TAPS) tool.

Journal Article Contemp Clin Trials · September 2016 Featured Publication BACKGROUND: Substance use and its associated use disorders are under-detected and under-treated in primary care. There is a need for a clinically useful brief screening and assessment instrument to identify primary care patients with substance use, sub-thr ... Full text Open Access Link to item Cite

Trends in cannabis use disorders among racial/ethnic population groups in the United States.

Journal Article Drug Alcohol Depend · August 1, 2016 Featured Publication BACKGROUND: Minority groups generally experience more disparities than whites in behavioral healthcare use. The population of racial/ethnic groups is growing faster than whites. Given increased concerns of cannabis use (CU) and its associations with health ... Full text Open Access Link to item Cite

Family substance use screening: less to hide, more to gain.

Journal Article Indian J Med Res · June 2016 Featured Publication Full text Open Access Link to item Cite

Substance use after bariatric surgery: A review.

Journal Article J Psychiatr Res · May 2016 Featured Publication BACKGROUND: Prevalence of obesity has increased dramatically. Obese individuals may undergo bariatric surgery to lose excessive body fat and mitigate obesity-related comorbidities. However, bariatric patients are particularly vulnerable to substance use pr ... Full text Open Access Link to item Cite

Substance abuse, treatment needs and access among female sex workers and non-sex workers in Pretoria, South Africa

Chapter · April 19, 2016 Featured Publication Background This study examined cross-sectional data collected from substance-using female sex workers (FSW) and non-sex workers (non-SW) in Pretoria, South Africa, who entered a randomized controlled trial. Methods Women who reported alcohol use and recent ... Open Access Cite

Nonmedical Opioid Pain Relievers and All-Cause Mortality: A 27-Year Follow-Up From the Epidemiologic Catchment Area Study.

Journal Article Am J Public Health · March 2016 Featured Publication OBJECTIVES: We investigated whether nonmedical opioid pain reliever use is associated with higher mortality in the general US population. METHODS: We assessed the history of nonmedical opioid pain reliever use among 9985 people interviewed at baseline of t ... Full text Open Access Link to item Cite

Cardiometabolic Risk Factors among Severely Obese Children and Adolescents in the United States, 1999-2012.

Journal Article Child Obes · February 2016 Featured Publication BACKGROUND: Severely obese children and adolescents are at high risk of suffering obesity-related comorbidities. This article is to examine the dose-response relationship between weight status and cardiometabolic risk factors among US adolescents. METHODS: ... Full text Open Access Link to item Cite

Using electronic health record data for substance use Screening, Brief Intervention, and Referral to Treatment among adults with type 2 diabetes: Design of a National Drug Abuse Treatment Clinical Trials Network study.

Journal Article Contemp Clin Trials · January 2016 Featured Publication BACKGROUND: The Affordable Care Act encourages healthcare systems to integrate behavioral and medical healthcare, as well as to employ electronic health records (EHRs) for health information exchange and quality improvement. Pragmatic research paradigms th ... Full text Open Access Link to item Cite

Association Between Substance Use and Gun-Related Behaviors.

Journal Article Epidemiol Rev · 2016 Featured Publication Gun-related violence is a public health concern. This study synthesizes findings on associations between substance use and gun-related behaviors. Searches through PubMed, Embase, and PsycINFO located 66 studies published in English between 1992 and 2014. M ... Full text Open Access Link to item Cite

Primary care for opioid use disorder.

Journal Article Subst Abuse Rehabil · 2016 Featured Publication Full text Open Access Link to item Cite

Trends and Correlates of Cannabis-involved Emergency Department Visits: 2004 to 2011.

Journal Article J Addict Med · 2016 Featured Publication OBJECTIVES: To examine trends and correlates of cannabis-involved emergency department (ED) visits in the United States from 2004 to 2011. METHODS: Data were obtained from the 2004 to 2011 Drug Abuse Warning Network. We analyzed trend in cannabis-involved ... Full text Open Access Link to item Cite

Reference periods in retrospective behavioral self-report: A qualitative investigation.

Journal Article Am J Addict · December 2015 Featured Publication BACKGROUND: Self-report questions in substance use research and clinical screening often ask individuals to reflect on behaviors, symptoms, or events over a specified time period. However, there are different ways of phrasing conceptually similar time fram ... Full text Open Access Link to item Cite

Substance use and mental diagnoses among adults with and without type 2 diabetes: Results from electronic health records data.

Journal Article Drug Alcohol Depend · November 1, 2015 Featured Publication BACKGROUND: Comorbid diabetes and substance use diagnoses (SUD) represent a hazardous combination, both in terms of healthcare cost and morbidity. To date, there is limited information about the association of SUD and related mental disorders with type 2 d ... Full text Open Access Link to item Cite

Mortality among heroin users and users of other internationally regulated drugs: A 27-year follow-up of users in the Epidemiologic Catchment Area Program household samples.

Journal Article Drug Alcohol Depend · November 1, 2015 Featured Publication BACKGROUND: In contrast to research on more restricted samples of drug users, epidemiological studies open up a view of death rates and survivorship of those who have tried heroin a few times, with no acceleration toward sustained use patterns often seen i ... Full text Open Access Link to item Cite

Smoking cessation interventions for adults aged 50 or older: A systematic review and meta-analysis.

Journal Article Drug Alcohol Depend · September 1, 2015 Featured Publication BACKGROUND: The older population size has increased substantially, and a considerable proportion of older adults are cigarette smokers. Quitting smoking is associated with reduced health risk. This review is among the first to quantitatively assess the rel ... Full text Open Access Link to item Cite

Psychotic experiences and risk of death in the general population: 24-27 year follow-up of the Epidemiologic Catchment Area study.

Journal Article Br J Psychiatry · July 2015 Featured Publication BACKGROUND: Psychotic experiences are common in the general population and are associated with adverse psychiatric and social outcomes, even in the absence of a psychotic disorder. AIMS: To examine the association between psychotic experiences and mortalit ... Full text Open Access Link to item Cite

Perceived cannabis use norms and cannabis use among adolescents in the United States.

Journal Article J Psychiatr Res · May 2015 Featured Publication Due to changes in cannabis policies, concerns about cannabis use (CU) in adolescents have increased. The population of nonwhite groups is growing quickly in the United States. We examined perceived CU norms and their association with CU and CU disorder (CU ... Full text Open Access Link to item Cite

Substance use disorders and co-morbidities among Asian Americans and Native Hawaiians/Pacific Islanders

Journal Article Psychological Medicine · February 12, 2015 Featured Publication Background Asian Americans (AAs) and Native Hawaiians/Pacific Islanders (NHs/PIs) are the fastest growing segments of the US population. However, their population sizes are small, and thus AAs and NHs/PIs are often aggregated into a single racial/ethnic gr ... Full text Open Access Cite

Substance use disorders and co-morbidities among Asian Americans and Native Hawaiians/Pacific Islanders.

Journal Article Psychol Med · February 2015 Featured Publication BACKGROUND: Asian Americans (AAs) and Native Hawaiians/Pacific Islanders (NHs/PIs) are the fastest growing segments of the US population. However, their population sizes are small, and thus AAs and NHs/PIs are often aggregated into a single racial/ethnic g ... Full text Open Access Link to item Cite

Associations between cigarette smoking and pain among veterans.

Journal Article Epidemiol Rev · 2015 Featured Publication Individuals with chronic pain often report using cigarettes to cope, and smoking and chronic pain appear prevalent among US veterans. Pain may be a barrier to cigarette cessation and abstinence in this population. Because of physiological effects, smoking ... Full text Open Access Link to item Cite

Sexual risk behaviors and HIV risk among Americans aged 50 years or older: a review.

Journal Article Subst Abuse Rehabil · 2015 Featured Publication Although HIV-related sexual risk behaviors have been studied extensively in adolescents and young adults, there is limited information about these behaviors among older Americans, which make up a growing segment of the US population and an understudied pop ... Full text Open Access Link to item Cite

EPIDEMIOLOGY OF USE OF TREATMENT SERVICES FOR SUBSTANCE USE PROBLEMS

Chapter · 2015 Featured Publication Cite

CIGARETTE SMOKING AMONG ADULTS AGED 45 AND OLDER IN THE UNITED STATES, 2002-2011

Chapter · 2015 Featured Publication Cite

Substance Use and Older People INTRODUCTION

Chapter · 2015 Featured Publication Cite

Introduction

Chapter · December 31, 2014 Featured Publication Cite

Recommendations

Chapter · December 31, 2014 Featured Publication Full text Cite

Pharmacological and Integrated Treatments in Older Adults with Substance Use Disorders

Chapter · December 31, 2014 Featured Publication As the number of older adults aged ≥50years rise and requests of treatment for substance use disorders increase, there is an emerging need to identify efficient interventions. Research on pharmacological management of substance abuse among older individual ... Full text Cite

Epidemiology and Demography of Illicit Drug Use and Drug Use Disorders Among Adults Aged 50 and Older

Chapter · December 31, 2014 Featured Publication Prevalence of illicit drug use is on the rise among people aged ≥50years and is projected to increase as baby boomers (born 1946-1964) age. Fuelling this increase are the large number of boomers and the popularity of substance use when they came of age. Th ... Full text Cite

Cigarette Smoking Among Adults Aged 45 and Older in the United States, 2002-2011

Chapter · December 31, 2014 Featured Publication Cigarette smoking continues to be the leading cause of preventable morbidity and mortality in the United States and worldwide. Recent global data indicate that current cigarette smoking prevalence ranges from 5.8% in India to 38.8% in Russia. Prevention ef ... Full text Cite

Substance Use and Older People

Book · December 31, 2014 Featured Publication Substance use and addiction is an increasing problem amongst older people. The identification of this problem is often more difficult in older patients and is frequently missed, particularly in the primary care context and in emergency departments, but als ... Full text Cite

Epidemiology of Use of Treatment Services for Substance Use Problems

Chapter · December 31, 2014 Featured Publication The need for substance abuse and dependence treatment among adults aged ≥50years is projected to grow over the next several years. This chapter reviews and summarizes studies on the epidemiology of substance abuse treatment service use for individuals aged ... Full text Cite

Tobacco Use Cessation

Chapter · December 31, 2014 Featured Publication Full text Cite

Nonmedical stimulant use among young Asian-Americans, Native Hawaiians/Pacific Islanders, and mixed-race individuals aged 12-34 years in the United States.

Journal Article J Psychiatr Res · December 2014 Featured Publication There are concerns over nonmedical use of prescription stimulants among youths, but little is known about the extent of use among young Asian-Americans, Native Hawaiians/Pacific Islanders (NHs/PIs), and mixed-race individuals-the fastest growing segments o ... Full text Open Access Link to item Cite

Suicidal ideation and substance use among adolescents and young adults: a bidirectional relation?

Journal Article Drug Alcohol Depend · September 1, 2014 Featured Publication OBJECTIVE: To examine reciprocal associations between substance use (cigarette smoking, use of alcohol, marijuana, and other illegal drugs) and suicidal ideation among adolescents and young adults (aged 11-21 at wave 1; aged 24-32 at wave 4). METHODS: Four ... Full text Open Access Link to item Cite

Psychopharmacology and the Consequences of Alcohol and Drug Interactions

Chapter · August 27, 2014 Featured Publication Full text Cite

E-cigarette prevalence and correlates of use among adolescents versus adults: a review and comparison.

Journal Article J Psychiatr Res · July 2014 Featured Publication Perceived safer than tobacco cigarettes, prevalence of electronic cigarette (e-cigarette) use is increasing. Analyses of cartridges suggest that e-cigarettes may pose health risks. In light of increased use and the potential for consequences, we searched G ... Full text Open Access Link to item Cite

Extended release naltrexone injection is performed in the majority of opioid dependent patients receiving outpatient induction: a very low dose naltrexone and buprenorphine open label trial.

Journal Article Drug Alcohol Depend · May 1, 2014 Featured Publication BACKGROUND: The approval of extended release injectable naltrexone (XR-NTX; Vivitrol(®)) has introduced a new option for treating opioid addiction, but studies are needed to identify its place within the spectrum of available therapies. The absence of phys ... Full text Open Access Link to item Cite

Substance use disorders and psychiatric comorbidity in mid and later life: a review.

Journal Article Int J Epidemiol · April 2014 Featured Publication BACKGROUND: Globally, adults aged 65 years or older will increase from 516 million in 2009 to an estimated 1.53 billion in 2050. Due to substance use at earlier ages that may continue into later life, and ageing-related changes in medical conditions, older ... Full text Open Access Link to item Cite

Cannabis use disorders are comparatively prevalent among nonwhite racial/ethnic groups and adolescents: a national study.

Journal Article J Psychiatr Res · March 2014 Featured Publication The racial/ethnic composition of the US population is shifting, with the nonwhite population growing faster than whites. We examined cannabis use disorder (CUD) prevalences and correlates in seven racial/ethnic groups. We included cannabis use (CU) prevale ... Full text Open Access Link to item Cite

Suicide and substance use among female veterans: a need for research.

Journal Article Drug Alcohol Depend · March 1, 2014 Featured Publication BACKGROUND: The number of female veterans is increasing. Veterans Administration (VA) enrollment increased over 40% from past eras. However, little research has focused on their mental health. We reviewed literature to examine associations of substance use ... Full text Open Access Link to item Cite

Introduction

Chapter · 2014 Featured Publication Cite

E-cigarette prevalence and correlates of use among adolescents versus adults: A review and comparison

Journal Article Journal of Psychiatric Research · 2014 Featured Publication Open Access Cite

Psychiatric correlates of snuff and chewing tobacco use.

Journal Article PLoS One · 2014 Featured Publication Compared to the association between cigarette smoking and psychiatric disorders, relatively little is known about the relationship between smokeless tobacco use and psychiatric disorders. To identify the psychiatric correlates of smokeless tobacco use, the ... Full text Open Access Link to item Cite

Illicit and nonmedical drug use among Asian Americans, Native Hawaiians/Pacific Islanders, and mixed-race individuals.

Journal Article Drug Alcohol Depend · December 1, 2013 Featured Publication BACKGROUND: The racial/ethnic composition of the United States is shifting rapidly, with non-Hispanic Asian-Americans, Native Hawaiians/Pacific Islanders (NHs/PIs), and mixed-race individuals the fastest growing segments of the population. We determined ne ... Full text Open Access Link to item Cite

Comorbid substance use disorders with other Axis I and II mental disorders among treatment-seeking Asian Americans, Native Hawaiians/Pacific Islanders, and mixed-race people.

Journal Article J Psychiatr Res · December 2013 Featured Publication Little is known about behavioral healthcare needs of Asian Americans (AAs), Native Hawaiians/Pacific Islanders (NHs/PIs), and mixed-race people (MRs)-the fastest growing segments of the U.S. population. We examined substance use disorder (SUD) prevalences ... Full text Open Access Link to item Cite

The relationship of mental and behavioral disorders to all-cause mortality in a 27-year follow-up of 4 epidemiologic catchment area samples.

Journal Article Am J Epidemiol · November 1, 2013 Featured Publication Subjects from the Epidemiologic Catchment Area Program, interviewed during 1979-1983, were linked to data in the National Death Index through 2007 to estimate the association of mental and behavioral disorders with death. There were more than 25 years of f ... Full text Open Access Link to item Cite

Smoking and opioid detoxification: behavioral changes and response to treatment.

Journal Article Nicotine Tob Res · October 2013 Featured Publication INTRODUCTION: The relevance of tobacco use in opioid addiction (OA) has generated a demand for available and more effective interventions. Thus, further analysis of less explored nicotine-opioid clinical interactions is warranted. METHODS: A post-hoc analy ... Full text Open Access Link to item Cite

Tobacco use among Asian Americans, Native Hawaiians/Pacific Islanders, and mixed-race individuals: 2002-2010.

Journal Article Drug Alcohol Depend · September 1, 2013 Featured Publication BACKGROUND: Non-Hispanic Asian Americans, Native Hawaiians/Pacific Islanders (NHs/PIs), and mixed-race individuals are the fastest growing segments of the US population. We examined prevalences and correlates of tobacco use among these understudied groups. ... Full text Open Access Link to item Cite

Referring heroin users from compulsory detoxification centers to community methadone maintenance treatment: a comparison of three models.

Journal Article BMC Public Health · August 13, 2013 Featured Publication BACKGROUND: Both compulsory detoxification treatment and community-based methadone maintenance treatment (MMT) exist for heroin addicts in China. We aim to examine the effectiveness of three intervention models for referring heroin addicts released from co ... Full text Open Access Link to item Cite

Substance Use among Adolescent Mothers: A Review.

Journal Article Child Youth Serv Rev · May 1, 2013 Featured Publication Maternal substance abuse is a critical problem, and adolescent mothers appear to be at high risk for such behaviors. We review studies on postpartum adolescent substance use to explore the extent of this problem and avenues for new research. Authors screen ... Full text Open Access Link to item Cite

Screening instruments for substance use and brief interventions targeting adolescents in primary care: a literature review.

Journal Article Addict Behav · May 2013 Featured Publication BACKGROUND: A review of the literature was conducted to examine substance use screening instruments commonly used with adolescents in medical settings, their comparative usefulness, and SBIRT (Screening, Brief Intervention, and Referral to Treatment). METH ... Full text Open Access Link to item Cite

Using electronic health records data to assess comorbidities of substance use and psychiatric diagnoses and treatment settings among adults.

Journal Article J Psychiatr Res · April 2013 Featured Publication OBJECTIVE: To examine prevalences of substance use disorders (SUD) and comprehensive patterns of comorbidities among psychiatric patients ages 18-64 years (N = 40,099) in an electronic health records (EHR) database. METHOD: DSM-IV diagnoses among psychiatr ... Full text Open Access Link to item Cite

Inhalants

Chapter · February 26, 2013 Featured Publication Full text Cite

Suicide and substance use among female veterans: A need for research

Journal Article Drug and Alcohol Dependence · 2013 Featured Publication Open Access Cite

The national drug abuse treatment clinical trials network data share project: website design, usage, challenges, and future directions.

Journal Article Clin Trials · 2013 Featured Publication BACKGROUND: There are many benefits of data sharing, including the promotion of new research from effective use of existing data, replication of findings through re-analysis of pooled data files, meta-analysis using individual patient data, and reinforceme ... Full text Open Access Link to item Cite

The Treatment Effectiveness Assessment (TEA).

Journal Article Subst Abuse Rehabil · 2013 Featured Publication Full text Open Access Link to item Cite

Prescription drug overdose: between patients and their doctors.

Journal Article Subst Abuse Rehabil · 2013 Featured Publication Full text Open Access Link to item Cite

Integrating substance abuse care with community diabetes care: implications for research and clinical practice.

Journal Article Subst Abuse Rehabil · January 1, 2013 Featured Publication Cigarette smoking and alcohol use are prevalent among individuals with diabetes in the US, but little is known about screening and treatment for substance use disorders in the diabetic population. This commentary discusses the scope and clinical implicatio ... Full text Open Access Link to item Cite

Food, class, and health: the role of the perceived body in the social reproduction of health.

Journal Article Health Commun · 2013 Featured Publication The association between social class and cardiovascular health is complex, involving a constant interplay of factors as individuals integrate external information from the media, health care providers, and people they know with personal experience to produ ... Full text Open Access Link to item Cite

Evaluating brief screeners to discriminate between drug use disorders in a sample of treatment-seeking adults.

Journal Article Gen Hosp Psychiatry · 2013 Featured Publication OBJECTIVE: The objective was to identify a potential core set of brief screeners for the detection of individuals with a substance use disorder (SUD) in medical settings. METHOD: Data were from two multisite studies that evaluated stimulant use outcomes of ... Full text Open Access Link to item Cite

Postpartum substance use and depressive symptoms: a review.

Journal Article Women Health · 2013 Featured Publication National survey data suggest that new mothers have high prevalences of alcohol and illicit drug use. Depression correlates with substance use, and new mothers with postpartum depression may be at high risk for substance use. Understanding postpartum substa ... Full text Open Access Link to item Cite

Inhalants

Chapter · 2013 Featured Publication Full text Cite

Alcohol limits in older people.

Journal Article Addiction · September 2012 Featured Publication Full text Open Access Link to item Cite

Datapoints: Use of medications and counseling for depression by Asian and multiple-race adolescents aged 12-17 years.

Journal Article Psychiatr Serv · September 1, 2012 Featured Publication Full text Open Access Link to item Cite

Risk profiles among adolescent nonmedical opioid users in the United States.

Journal Article Addict Behav · August 2012 Featured Publication Although prior research has provided data on nonmedical use of opioids in adolescents, studies examining the heterogeneity of risk are limited. The present study extends prior research by deepening the understanding of adolescent nonmedical opioid use by s ... Full text Open Access Link to item Cite

Alcohol and drug use disorders among adults in emergency department settings in the United States.

Journal Article Ann Emerg Med · August 2012 Featured Publication STUDY OBJECTIVE: Improving identification and treatment for substance use disorders is a national priority, but data about various drug use disorders encountered in emergency departments (EDs) are lacking. We examine past-year substance use and substance u ... Full text Open Access Link to item Cite

Correlates of handgun carrying among adolescents in the United States.

Journal Article J Interpers Violence · July 2012 Featured Publication Weapon-related violence, especially the use of handguns, among adolescents is a serious public health concern. Using public-use data file from the adolescent sample (N = 17,842) in the 2008 National Survey on Drug Use and Health (NSDUH), this study examine ... Full text Open Access Link to item Cite

A dimensional approach to understanding severity estimates and risk correlates of marijuana abuse and dependence in adults.

Journal Article Int J Methods Psychiatr Res · June 2012 Featured Publication While item response theory (IRT) research shows a latent severity trait underlying response patterns of substance abuse and dependence symptoms, little is known about IRT-based severity estimates in relation to clinically relevant measures. In response to ... Full text Open Access Link to item Cite

Advances in opioid antagonist treatment for opioid addiction.

Journal Article Psychiatr Clin North Am · June 2012 Featured Publication Full text Open Access Link to item Cite

The combination very low-dose naltrexone-clonidine in the management of opioid withdrawal.

Journal Article Am J Drug Alcohol Abuse · May 2012 Featured Publication BACKGROUND: The management of withdrawal absorbs substantial clinical efforts in opioid dependence (OD). The real challenge lies in improving current pharmacotherapies. Although widely used, clonidine causes problematic adverse effects and does not allevia ... Full text Open Access Link to item Cite

Screening for alcohol and drug use disorders among adults in primary care: a review.

Journal Article Subst Abuse Rehabil · April 2012 Featured Publication BACKGROUND: The Patient Protection and Affordable Care Act of 2010 supports integration of substance abuse interventions and treatments into the mainstream health care system. Thus, effective screening and intervention for substance use disorders in health ... Full text Open Access Link to item Cite

Survey of methadone-drug interactions among patients of methadone maintenance treatment program in Taiwan.

Journal Article Subst Abuse Treat Prev Policy · March 20, 2012 Featured Publication BACKGROUND: Although methadone has been used for the maintenance treatment of opioid dependence for decades, it was not introduced in China or Taiwan until 2000s. Methadone-drug interactions (MDIs) have been shown to cause many adverse effects. However, su ... Full text Open Access Link to item Cite

Buprenorphine-mediated transition from opioid agonist to antagonist treatment: state of the art and new perspectives.

Journal Article Curr Drug Abuse Rev · March 2012 Featured Publication Constant refinement of opioid dependence (OD) therapies is a condition to promote treatment access and delivery. Among other applications, the partial opioid agonist buprenorphine has been studied to improve evidence-based interventions for the transfer of ... Full text Open Access Link to item Cite

Alcohol and drug dependence symptom items as brief screeners for substance use disorders: results from the Clinical Trials Network.

Journal Article J Psychiatr Res · March 2012 Featured Publication AIM: To address an urgent need for screening of substance use problems in medical settings, we examined substance-specific dependence criteria as potential brief screeners for the detection of patients with a substance use disorder (SUD). METHODS: The samp ... Full text Open Access Link to item Cite

Electronic health records: essential tools in integrating substance abuse treatment with primary care.

Journal Article Subst Abuse Rehabil · 2012 Featured Publication While substance use problems are considered to be common in medical settings, they are not systematically assessed and diagnosed for treatment management. Research data suggest that the majority of individuals with a substance use disorder either do not us ... Full text Open Access Link to item Cite

The Treatment Effectiveness Assessment (TEA): an efficient, patient-centered instrument for evaluating progress in recovery from addiction.

Journal Article Subst Abuse Rehabil · January 1, 2012 Featured Publication The fields of addiction medicine and addiction research have long sought an efficient yet comprehensive instrument to assess patient progress in treatment and recovery. Traditional tools are expensive, time consuming, complex, and based on topics that clin ... Full text Open Access Link to item Cite

Use of Salvia divinorum in a nationally representative sample.

Journal Article Am J Drug Alcohol Abuse · January 2012 Featured Publication BACKGROUND: Salvia divinorum has known hallucinogenic effects and is legal in most parts of the United States. Given that this psychoactive substance has a potential of misuse and abuse, further data regarding the clinical and psychosocial factors associat ... Full text Open Access Link to item Cite

Patterns of tobacco use and tobacco-related psychiatric morbidity and substance use among middle-aged and older adults in the United States.

Journal Article Aging Ment Health · 2012 Featured Publication OBJECTIVES: To examine prevalence of tobacco use and identify psychiatric symptoms and substance use correlates of tobacco use comparing adults 50-64 years of age with those 65+ years of age (N = 10,891). METHODS: Data were from the 2008-2009 US National S ... Full text Open Access Link to item Cite

Substance abuse among individuals with intellectual disabilities.

Journal Article Res Dev Disabil · 2012 Featured Publication Individuals with disabilities are a growing population that confronts multiple disadvantages from social and environmental determinants of health. In particular, the 7-8 million people in the U.S. with an intellectual disability (ID) suffer disproportionat ... Full text Open Access Link to item Cite

Treatment use and barriers among adolescents with prescription opioid use disorders.

Journal Article Addict Behav · December 2011 Featured Publication BACKGROUND: This study examined national trends, patterns, correlates, and barriers to substance abuse treatment use by adolescents aged 12-17 years who met at least one of the past-year criteria for prescription opioid abuse or dependence (N=1788). METHOD ... Full text Open Access Link to item Cite

Substance use disorders and comorbid Axis I and II psychiatric disorders among young psychiatric patients: findings from a large electronic health records database.

Journal Article J Psychiatr Res · November 2011 Featured Publication This study examined the prevalence of substance use disorders (SUDs) among psychiatric patients aged 2-17 years in an electronic health records database (N=11,457) and determined patterns of comorbid diagnoses among patients with a SUD to inform emerging c ... Full text Open Access Link to item Cite

Racial/ethnic variations in substance-related disorders among adolescents in the United States.

Journal Article Arch Gen Psychiatry · November 2011 Featured Publication CONTEXT: While young racial/ethnic groups are the fastest growing population in the United States, data about substance-related disorders among adolescents of various racial/ethnic backgrounds are lacking. OBJECTIVE: To examine the magnitude of past-year D ... Full text Open Access Link to item Cite

Use of item response theory and latent class analysis to link poly-substance use disorders with addiction severity, HIV risk, and quality of life among opioid-dependent patients in the Clinical Trials Network.

Journal Article Drug Alcohol Depend · November 1, 2011 Featured Publication BACKGROUND: This study applied item response theory (IRT) and latent class analysis (LCA) procedures to examine the dimensionality and heterogeneity of comorbid substance use disorders (SUDs) and explored their utility for standard clinical assessments, in ... Full text Open Access Link to item Cite

Conducting research with racial/ethnic minorities: methodological lessons from the NIDA Clinical Trials Network.

Journal Article Am J Drug Alcohol Abuse · September 2011 Featured Publication BACKGROUND: Multiple studies in the National Institute on Drug Abuse Clinical Trials Network (CTN) demonstrate strategies for conducting effective substance abuse treatment research with racial/ethnic minorities (REMs). OBJECTIVES: The objectives of this a ... Full text Open Access Link to item Cite

The epidemiology of alcohol use disorders and subthreshold dependence in a middle-aged and elderly community sample.

Journal Article Am J Geriatr Psychiatry · August 2011 Featured Publication OBJECTIVE: To estimate 1-year prevalence and correlates of alcohol abuse, dependence, and subthreshold dependence (diagnostic orphans) among middle-aged and elderly persons in the United States. DESIGN: 2005-2007 National Surveys on Drug Use and Health. ME ... Full text Open Access Link to item Cite

Buprenorphine for prescription opioid addiction in a patient with depression and alcohol dependence.

Journal Article Am J Psychiatry · July 2011 Featured Publication Full text Open Access Link to item Cite

Pharmacological enhancement of naltrexone treatment for opioid dependence: a review.

Journal Article Subst Abuse Rehabil · June 2011 Featured Publication PURPOSE: Opioid dependence (OD) is a serious and growing clinical condition with increasing social costs that requires expanding treatment beyond opioid agonist substitution. The opioid antagonist naltrexone has displayed a remarkable association of theore ... Full text Open Access Link to item Cite

Problem drinking and low-dose naltrexone-assisted opioid detoxification.

Journal Article J Stud Alcohol Drugs · May 2011 Featured Publication OBJECTIVE: The influence of alcohol use on opioid dependence is a major problem that warrants a search for more effective treatment strategies. The addition of very-low-dose naltrexone (VLNTX) to methadone taper was recently associated with reduced withdra ... Full text Open Access Link to item Cite

Differences in onset and abuse/dependence episodes between prescription opioids and heroin: results from the National Epidemiologic Survey on Alcohol and Related Conditions.

Journal Article Subst Abuse Rehabil · May 2011 Featured Publication OBJECTIVES: To examine patterns of onset and abuse/dependence episodes of prescription opioid (PO) and heroin use disorders in a national sample of adults, and to explore differences by gender and substance abuse treatment status. METHODS: Analyses of data ... Full text Open Access Link to item Cite

The prevalence and clinical significance of inhalant withdrawal symptoms among a national sample.

Journal Article Subst Abuse Rehabil · April 2011 Featured Publication BACKGROUND: Inhalants are among the most common and dangerous forms of substance use, but very little research on inhalant use disorders exist. Unlike other substances, the Diagnostic and Statistical Manual, 4th edition (DSM-IV) indicates that inhalants do ... Full text Open Access Link to item Cite

Illicit and nonmedical drug use among older adults: a review.

Journal Article J Aging Health · April 2011 Featured Publication OBJECTIVE: Substance abuse among older adults is a looming public health concern. The number of Americans aged 50+ years with a substance use disorder is projected to double from 2.8 million in 2002-2006 to 5.7 million in 2020. The authors provide a review ... Full text Open Access Link to item Cite

Recent national trends in Salvia divinorum use and substance-use disorders among recent and former Salvia divinorum users compared with nonusers.

Journal Article Subst Abuse Rehabil · April 2011 Featured Publication CONTEXT: Media and scientific reports have indicated an increase in recreational use of Salvia divinorum. Epidemiological data are lacking on the trends, prevalence, and correlates of S. divinorum use in large representative samples, as well as the extent ... Full text Open Access Link to item Cite

Abuse and dependence on prescription opioids in adults: a mixture categorical and dimensional approach to diagnostic classification.

Journal Article Psychol Med · March 2011 Featured Publication BACKGROUND: For the emerging DSM-V, it has been recommended that dimensional and categorical methods be used simultaneously in diagnostic classification; however, little is known about this combined approach for abuse and dependence. METHOD: Using data (n= ... Full text Open Access Link to item Cite

How do prescription opioid users differ from users of heroin or other drugs in psychopathology: results from the National Epidemiologic Survey on Alcohol and Related Conditions.

Journal Article J Addict Med · March 2011 Featured Publication OBJECTIVES: To study substance use and psychiatric disorders among prescription opioid users, heroin users, and non-opioid drug users in a national sample of adults. METHODS: Analyses of data from the 2001-2002 National Epidemiologic Survey on Alcohol and ... Full text Open Access Link to item Cite

Depressive symptoms, substance use, and HIV-related high-risk behaviors among opioid-dependent individuals: results from the Clinical Trials Network.

Journal Article Subst Use Misuse · 2011 Featured Publication The sample included 343 opioid-dependent adults enrolled in two national multisite studies of the National Drug Abuse Treatment Clinical Trials Network (CTN001-002). Opioid-dependent individuals were recruited from 12 sites across the United States from Ja ... Full text Open Access Link to item Cite

Co-occurring amphetamine use and associated medical and psychiatric comorbidity among opioid-dependent adults: results from the Clinical Trials Network.

Journal Article Subst Abuse Rehabil · January 1, 2011 Featured Publication BACKGROUND: In response to the rising rate of treatment admissions related to illicit use of amphetamines (eg, methamphetamine), we examined the prevalence of amphetamine use among treatment-seeking, opioid-dependent adults, explored whether amphetamine us ... Full text Open Access Link to item Cite

Gender and racial/ethnic differences in addiction severity, HIV risk, and quality of life among adults in opioid detoxification: results from the National Drug Abuse Treatment Clinical Trials Network.

Journal Article Subst Abuse Rehabil · December 2010 Featured Publication PURPOSE: Detoxification often serves as an initial contact for treatment and represents an opportunity for engaging patients in aftercare to prevent relapse. However, there is limited information concerning clinical profiles of individuals seeking detoxifi ... Full text Open Access Link to item Cite

Subtypes of nonmedical opioid users: results from the national epidemiologic survey on alcohol and related conditions.

Journal Article Drug Alcohol Depend · November 1, 2010 Featured Publication AIMS: To identify subtypes of nonmedical opioid users, gender variations in psychiatric disorders, and quality of life in a representative sample of adults. METHODS: Analyses of data from the 2001-2002 National Epidemiologic Survey on Alcohol and Related C ... Full text Open Access Link to item Cite

Substance abuse and rehabilitation: responding to the global burden of diseases attributable to substance abuse.

Journal Article Subst Abuse Rehabil · October 2010 Featured Publication Alcohol, tobacco, and illegal drug use are pervasive throughout the world. Substance use problems are among the major contributors to the global disease burden, which includes disability and mortality. The benefits of treatment far outweigh the economic co ... Full text Open Access Link to item Cite

Reduced cannabis use after low-dose naltrexone addition to opioid detoxification.

Journal Article J Clin Psychopharmacol · August 2010 Featured Publication Full text Open Access Link to item Cite

Using a latent variable approach to inform gender and racial/ethnic differences in cocaine dependence: a National Drug Abuse Treatment Clinical Trials Network study.

Journal Article J Subst Abuse Treat · June 2010 Featured Publication This study applies a latent variable approach to examine gender and racial/ethnic differences in cocaine dependence, to determine the presence of differential item functioning (DIF) or item-response bias to diagnostic questions of cocaine dependence, and t ... Full text Open Access Link to item Cite

An item response theory analysis of DSM-IV criteria for hallucinogen abuse and dependence in adolescents.

Journal Article Addict Behav · March 2010 Featured Publication AIM: This study applied both item response theory (IRT) and multiple indicators-multiple causes (MIMIC) methods to evaluate item-level psychometric properties of diagnostic questions for hallucinogen use disorders (HUDs), differential item functioning (DIF ... Full text Open Access Link to item Cite

Inhalant‐Related Disorders

Journal Article · January 30, 2010 Featured Publication AbstractInhalant use is the deliberate ingestion of volatile substances, via a number of methods: (1) “sniffing” or “snorting” fumes from containers; (2) spraying aerosols directly into the nose or mouth; (3) “ba ... Full text Cite

The epidemiology of alcohol use disorders and subthreshold dependence in a middle-aged and elderly community sample

Journal Article American Journal of Geriatric Psychiatry · 2010 Featured Publication OBJECTIVE: To estimate 1-year prevalence and correlates of alcohol abuse, dependence, and subthreshold dependence (diagnostic orphans) among middle-aged and elderly persons in the United States. DESIGN: 2005-2007 National Surveys on Drug Use and Health. ME ... Full text Open Access Cite

Drs. Blazer and Wu Reply.

Journal Article Am J Psychiatry · January 2010 Featured Publication Full text Open Access Link to item Cite

The epidemiology of at-risk and binge drinking among middle-aged and elderly community adults: National Survey on Drug Use and Health.

Journal Article Am J Psychiatry · October 2009 Featured Publication OBJECTIVE: The purpose of this article was to estimate the prevalence, distribution, and correlates of at-risk alcohol use (especially binge drinking) among middle-aged and elderly persons in the United States and to compare at-risk alcohol use between wom ... Full text Open Access Link to item Cite

Hallucinogen-related disorders in a national sample of adolescents: the influence of ecstasy/MDMA use.

Journal Article Drug Alcohol Depend · September 1, 2009 Featured Publication AIMS: To present the prevalence and correlates of hallucinogen use disorders (HUDs: abuse or dependence) and subthreshold dependence. METHODS: The study sample included adolescents aged 12-17 years (N=55,286) who participated in the National Survey on Drug ... Full text Open Access Link to item Cite

The construct and measurement equivalence of cocaine and opioid dependences: a National Drug Abuse Treatment Clinical Trials Network (CTN) study.

Journal Article Drug Alcohol Depend · August 1, 2009 Featured Publication INTRODUCTION: Although DSM-IV criteria are widely used in making diagnoses of substance use disorders, gaps exist regarding diagnosis classification, use of dependence criteria, and effects of measurement bias on diagnosis assessment. We examined the const ... Full text Open Access Link to item Cite

The high prevalence of substance use disorders among recent MDMA users compared with other drug users: Implications for intervention.

Journal Article Addict Behav · August 2009 Featured Publication AIM: In light of the resurgence in MDMA use and its association with polysubstance use, we investigated the 12-month prevalence of substance use disorders (SUDs) among adult MDMA users to determine whether they are at risk of other drug-related problems th ... Full text Open Access Link to item Cite

Association of MDMA/ecstasy and other substance use with self-reported sexually transmitted diseases among college-aged adults: a national study.

Journal Article Public Health · August 2009 Featured Publication OBJECTIVES: MDMA/ecstasy use among college students has increased and reportedly leads to risky sexual behaviours. However, little is known about its association with sexually transmitted diseases (STDs). To evaluate this public health concern, this study ... Full text Open Access Link to item Cite

Nonprescription use of pain relievers by middle-aged and elderly community-living adults: National Survey on Drug Use and Health.

Journal Article J Am Geriatr Soc · July 2009 Featured Publication OBJECTIVES: To estimate the frequency, distribution, and correlates of nonprescription use of pain relievers by middle-aged and elderly persons in the United States. DESIGN: Cross-sectional data analysis of a national community survey. SETTING: The 2005 an ... Full text Open Access Link to item Cite

Substance abuse, treatment needs and access among female sex workers and non-sex workers in Pretoria, South Africa.

Journal Article Subst Abuse Treat Prev Policy · May 27, 2009 Featured Publication BACKGROUND: This study examined cross-sectional data collected from substance-using female sex workers (FSW) and non-sex workers (non-SW) in Pretoria, South Africa, who entered a randomized controlled trial. METHODS: Women who reported alcohol use and rece ... Full text Open Access Link to item Cite

Construct and differential item functioning in the assessment of prescription opioid use disorders among American adolescents.

Journal Article J Am Acad Child Adolesc Psychiatry · May 2009 Featured Publication OBJECTIVE: To examine the psychometric properties of diagnostic criteria for prescription analgesic opioid use disorders (OUDs) and to identify background predictors of a latent continuum for OUD liability. METHOD: Data were drawn from the adolescent sampl ... Full text Open Access Link to item Cite

An item response theory modeling of alcohol and marijuana dependences: a National Drug Abuse Treatment Clinical Trials Network study.

Journal Article J Stud Alcohol Drugs · May 2009 Featured Publication OBJECTIVE: The aim of this study was to examine psychometric properties of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), diagnostics criteria for alcohol and marijuana dependences among 462 alcohol users and 311 mariju ... Full text Open Access Link to item Cite

Very low dose naltrexone addition in opioid detoxification: a randomized, controlled trial.

Journal Article Addict Biol · April 2009 Featured Publication Although current treatments for opioid detoxification are not always effective, medical detoxification remains a required step before long-term interventions. The use of opioid antagonist medications to improve detoxification has produced inconsistent resu ... Full text Open Access Link to item Cite

The impact of the CONSORT statement on reporting of randomized clinical trials in psychiatry.

Journal Article Contemp Clin Trials · March 2009 Featured Publication To determine whether the CONSORT recommendations influenced the quality of reporting of randomized controlled trials (RCTs) in the field of psychiatry, we evaluated the quality of clinical trial reports before and after the introduction of CONSORT statemen ... Full text Open Access Link to item Cite

The epidemiology of substance use and disorders among middle aged and elderly community adults: national survey on drug use and health.

Journal Article Am J Geriatr Psychiatry · March 2009 Featured Publication OBJECTIVE: To estimate the prevalence, distribution, and correlates of drug use among middle aged and elderly persons in the United States and to compare with alcohol use in this age group. SETTING: The 2005 and 2006 National Surveys on Drug Use and Health ... Full text Open Access Link to item Cite

Early outcomes following low dose naltrexone enhancement of opioid detoxification.

Journal Article Am J Addict · 2009 Featured Publication Although withdrawal severity and treatment completion are the initial focus of opioid detoxification, post-detoxification outcome better defines effective interventions. Very low dose naltrexone (VLNTX) in addition to methadone taper was recently associate ... Full text Open Access Link to item Cite

The variety of ecstasy/MDMA users: results from the National Epidemiologic Survey on alcohol and related conditions.

Journal Article Am J Addict · 2009 Featured Publication This study investigates the potential heterogeneity of ecstasy or MDMA (3,4-methylenedioxy-N-methylamphetamine) users. Data came from the 2001-2002 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). Latent class analysis (LCA) and mu ... Full text Open Access Link to item Cite

Heterogeneity of stimulant dependence: a national drug abuse treatment clinical trials network study.

Journal Article Am J Addict · 2009 Featured Publication We investigated the presence of DSM-IV subtyping for dependence on cocaine and amphetamines (with versus without physical dependence) among outpatient stimulant users enrolled in a multisite study of the Clinical Trials Network (CTN). Three mutually exclus ... Full text Open Access Link to item Cite

Relationship of the serotonin transporter with prolactin response to meta-chlorophenylpiperazine in cocaine dependence.

Journal Article J Psychiatr Res · October 2008 Featured Publication BACKGROUND: Preclinical evidence indicates that exposure to cocaine influences the activity of the serotonin transporter (5-HTT) as well as several 5-HT receptor subtypes. However, little is known about the relationship between the 5-HTT and 5-HT receptors ... Full text Link to item Cite

Prescription pain reliever abuse and dependence among adolescents: a nationally representative study.

Journal Article J Am Acad Child Adolesc Psychiatry · September 2008 Featured Publication OBJECTIVE: We examined the prevalence, patterns, and correlates of adolescents' abuse, subthreshold dependence ("diagnostic orphans"), and dependence on prescription pain relievers (PPRs) such as opioids in a representative national sample (N = 36,992). ME ... Full text Open Access Link to item Cite

Substance use disorders among inhalant users: results from the National Epidemiologic Survey on alcohol and related conditions.

Journal Article Addict Behav · July 2008 Featured Publication OBJECTIVE: To assess the prevalence, correlates, and age of onset of DSM-IV substance use disorders (SUDs) among adult inhalant users. METHODS: Analyses were based on structured psychiatric interviews of a nationally representative sample of 43,093 US adul ... Full text Open Access Link to item Cite

Non-prescribed use of pain relievers among adolescents in the United States.

Journal Article Drug Alcohol Depend · April 1, 2008 Featured Publication BACKGROUND: We examined gender-specific prevalences, patterns, and correlates of non-prescribed use of pain relievers - mainly opioids - in a representative sample of American adolescents (N=18,678). METHODS: Data were drawn from the public use data file o ... Full text Open Access Link to item Cite

Inhalant use among incarcerated adolescents in the United States: prevalence, characteristics, and correlates of use.

Journal Article Drug Alcohol Depend · March 1, 2008 Featured Publication OBJECTIVE: To characterize patterns and correlates of inhalant use among incarcerated youth. METHOD: Residents (N=723) of 27 Missouri Division of Youth Services facilities completed interviews assessing substance use, psychiatric symptoms, antisocial trait ... Full text Open Access Link to item Cite

Hallucinogen use disorders among adult users of MDMA and other hallucinogens.

Journal Article Am J Addict · 2008 Featured Publication We investigated the prevalence, patterns, and correlates of past-year DSM-IV hallucinogen use disorders (HUDs) among past-year users of MDMA and other hallucinogens from a sample of Americans 18 or older (n = 37,227). Users were categorized as MDMA users a ... Full text Open Access Link to item Cite

Infrequent illicit methadone use among stimulant-using patients in methadone maintenance treatment programs: a national drug abuse treatment clinical trials network study.

Journal Article Am J Addict · 2008 Featured Publication We sought to determine the prevalence, patterns, and correlates of past-month illicit methadone use and history of regular illicit use among stimulant-using methadone maintenance treatment patients. We obtained self-reported information on illicit methadon ... Full text Open Access Link to item Cite

Effectiveness of low-dose naltrexone in the post-detoxification treatment of opioid dependence.

Journal Article J Clin Psychopharmacol · October 2007 Featured Publication BACKGROUND: The clinical use of naltrexone (NTX) in the treatment of opioid dependence has been limited because of poor compliance and inconsistent outcomes. In particular, the therapeutic benefit of extended treatment with NTX after opioid detoxification ... Full text Open Access Link to item Cite

Misuse of methamphetamine and prescription stimulants among youths and young adults in the community.

Journal Article Drug Alcohol Depend · July 10, 2007 Featured Publication BACKGROUND: Gender differences in the prevalence and characteristics of misuse of methamphetamine (meth) and prescription stimulants were examined in a representative US sample of youths and young adults aged 16-25 (N=24,409). METHODS: Stimulant misusers w ... Full text Open Access Link to item Cite

Psychiatric disorders in inhalant users: results from The National Epidemiologic Survey on Alcohol and Related Conditions.

Journal Article Drug Alcohol Depend · May 11, 2007 Featured Publication OBJECTIVE: To examine the prevalence and correlates of mood, anxiety, and personality disorders among lifetime inhalant users. METHODS: Statistical analyses were based on data from the 2001-2002 National Epidemiologic Survey on Alcohol and Related Conditio ... Full text Open Access Link to item Cite

Alcohol use disorders and the use of treatment services among college-age young adults.

Journal Article Psychiatr Serv · February 2007 Featured Publication OBJECTIVES: This study examined the utilization of and the perceived need for alcohol treatment services among college-age young adults (18-22 years) according to their educational status: full-time college students, part-time college students, noncollege ... Full text Open Access Link to item Cite

Is inhalant use a risk factor for heroin and injection drug use among adolescents in the United States?

Journal Article Addict Behav · February 2007 Featured Publication PURPOSE: We examined whether inhalant use was associated with heroin and injection drug use (IDU) among adolescents aged 12 to 17 in the United States. METHODS: Data were drawn from the 2002/2003 administrations of the National Survey on Drug Use and Healt ... Full text Open Access Link to item Cite

Trends in nonheroin opioid abuse admissions: 1992-2004.

Journal Article J Opioid Manag · 2007 Featured Publication AIMS: This study examines trends for treatment admissions for nonheroin opioid abuse from 1992 to 2004. METHODS: Databases from the Substance Abuse Mental Health Services Administration (SAMHSA, U.S.A.): Treatment Episode Data Set (TEDS) were used to exami ... Full text Link to item Cite

Corrigendum to "Concurrent use of methamphetamine, MDMA, LSD, ketamine, GHB, and flunitrazepam among American youths" [Drug and Alcohol Dependence 84 (1) (2006) 102-113] (DOI:10.1016/j.drugalcdep.2006.01.002)

Journal Article Drug and Alcohol Dependence · 2007 Featured Publication Full text Open Access Cite

Inhalant use and disorders among adults in the United States.

Journal Article Drug Alcohol Depend · October 15, 2006 Featured Publication OBJECTIVE: To examine the patterns of adult inhalant use and correlates of inhalant use disorder. METHOD: We drew study data from the 2002 and 2003 National Surveys on Drug Use and Health (NSDUH). We used logistic regression to identify the characteristics ... Full text Open Access Link to item Cite

Concurrent use of methamphetamine, MDMA, LSD, ketamine, GHB, and flunitrazepam among American youths.

Journal Article Drug Alcohol Depend · September 1, 2006 Featured Publication BACKGROUND: The magnitude and the characteristics of the use of methamphetamine, MDMA (Ecstasy), LSD (d-lysergic acid diethylamide), ketamine, GHB (gamma-hydroxybutyrate), and flunitrazepam (Rohypnol) were examined in a probability sample of the U.S. civil ... Full text Open Access Link to item Cite

Psychiatric symptoms and substance use disorders in a nationally representative sample of American adolescents involved with foster care.

Journal Article J Adolesc Health · April 2006 Featured Publication PURPOSE: To ascertain the prevalence of psychiatric symptoms and substance use disorders among adolescents with a lifetime history of foster care placement, using data from a nationally representative sample of U.S. adolescents. METHODS: We studied adolesc ... Full text Open Access Link to item Cite

Use of alcohol treatment and mental health services among adolescents with alcohol use disorders.

Journal Article Psychiatr Serv · January 2006 Featured Publication OBJECTIVE: This study examined the use of and perceived need for alcohol treatment services among adolescents (aged 12 to 17 years) who received mental health services in the previous year compared with same-aged adolescents who did not receive such servic ... Full text Open Access Link to item Cite

Use of substance abuse services by young uninsured american adults.

Journal Article Psychiatr Serv · August 2005 Featured Publication OBJECTIVES: This study examined the prevalence and correlates of substance abuse service use among uninsured young adults aged 18 to 34 years (N=24,282). METHODS: Data were drawn from the 1999 National Household Survey on Drug Abuse. Logistic regression wa ... Full text Open Access Link to item Cite

Use of nitrite inhalants ("poppers") among American youth.

Journal Article J Adolesc Health · July 2005 Featured Publication PURPOSE: We examined the patterns and correlates of nitrite inhalant use among adolescents aged 12 to 17 years. METHODS: Study data were drawn from the 2000 and 2001 National Household Surveys on Drug Abuse. Logistic regression was used to identify the cha ... Full text Open Access Link to item Cite

High prevalence of substance use disorders among adolescents who use marijuana and inhalants.

Journal Article Drug Alcohol Depend · April 4, 2005 Featured Publication BACKGROUND: We examined the association between the use of inhalants, marijuana, and other drugs and recent DSM-IV substance use disorders among adolescents aged 12-17 years. METHODS: Data were drawn from 2000 to 2001 National Household Surveys on Drug Abu ... Full text Open Access Link to item Cite

Cocaine use and the occurrence of panic attacks in the community: a case-crossover approach.

Journal Article Subst Use Misuse · 2005 Featured Publication The epidemiologic case-crossover method is a powerful tool for research on suspected hazards of illegal drug use, the advantage being a subject-as-own-control approach that constrains stable individual-level susceptibility traits. Here, we use the case-cro ... Full text Open Access Link to item Cite

Inhalant abuse and dependence among adolescents in the United States.

Journal Article J Am Acad Child Adolesc Psychiatry · October 2004 Featured Publication OBJECTIVE: To examine the patterns of inhalant use and correlates of the progression from inhalant use to abuse and dependence among adolescents aged 12 to 17. METHOD: Study data were drawn from the 2000 and 2001 National Household Surveys on Drug Abuse. M ... Full text Open Access Link to item Cite

Alcohol dependence and use of treatment services among women in the community.

Journal Article Am J Psychiatry · October 2004 Featured Publication OBJECTIVE: This study examined the extent and characteristics of alcohol dependence and the perceived need for and use of alcohol treatment services among women compared with men in a nonclinical sample of adults 18-64 years of age. METHOD: Data were drawn ... Full text Open Access Link to item Cite

Private health insurance coverage for substance abuse and mental health services, 1995 to 1998.

Journal Article Psychiatr Serv · February 2004 Featured Publication Four years of data from the National Household Survey on Drug Abuse were combined to examine the characteristics of underinsurance in a sample of privately insured Americans aged 18 to 64. Among these adults, 38 percent (45 million) reported not having beh ... Full text Open Access Link to item Cite

Injection drug use among stimulant users in a national sample.

Journal Article Am J Drug Alcohol Abuse · 2004 Featured Publication OBJECTIVE: This study examined the correlates of injection drug use (IDU) in a community sample of psychostimulant users. Factors related to the cessation of illicit drug use and substance abuse service utilization were also determined among a subsample of ... Full text Open Access Link to item Cite

Substance use, dependence, and service utilization among the US uninsured nonelderly population.

Journal Article Am J Public Health · December 2003 Featured Publication OBJECTIVES: We examined the prevalence and correlates of substance use, dependence, and service utilization among uninsured persons aged 12 to 64 years. METHODS: We drew study data from the 1998 National Household Survey on Drug Abuse. RESULTS: An estimate ... Full text Open Access Link to item Cite

Use of substance abuse treatment services by persons with mental health and substance use problems.

Journal Article Psychiatr Serv · March 2003 Featured Publication OBJECTIVES: This study provided population estimates of mental syndromes and substance use problems and examined whether the co-occurrence of mental health and substance use problems was associated with the use of substance abuse treatment services. METHOD ... Full text Open Access Link to item Cite

The relationship between employment and substance use among students aged 12 to 17.

Journal Article J Adolesc Health · January 2003 Featured Publication PURPOSE: To examine the association between employment status and substance use among students aged 12 to 17 years. METHODS: Secondary analysis of data from the 1995 and 1996 National Household Surveys on Drug Abuse was conducted. The survey is a primary s ... Full text Open Access Link to item Cite

Psychostimulant dependence in a community sample.

Journal Article Subst Use Misuse · January 2003 Featured Publication OBJECTIVE: To examine the prevalence of psychostimulant dependence and the characteristics associated with nonmedical users' development of dependence. METHODS: The study sample was drawn from the 1995 to 1998 National Household Surveys on Drug Abuse. Stat ... Full text Open Access Link to item Cite

The estimated rate of depressed mood in US adults: recent evidence for a peak in later life.

Journal Article J Affect Disord · November 2000 Featured Publication OBJECTIVE: The main aim of this study is to add new evidence on the descriptive epidemiology of depressed mood, and to investigate suspected determinants for depressed mood in adulthood. METHODS: The data are from a continuing survey of a nationally repres ... Full text Open Access Link to item Cite

The use of the case-crossover design in studying illicit drug use.

Journal Article Subst Use Misuse · 2000 Featured Publication The case-crossover design was developed to study time-varying exposures that cause transient excess risk of acute health events. It is a variant of case-control and subject-as-own-control research designs, involving use of information about exposure histor ... Full text Open Access Link to item Cite

Tobacco smoking and depressed mood in late childhood and early adolescence.

Journal Article Am J Public Health · December 1999 Featured Publication OBJECTIVES: This study builds on previous observations about a suspected causal association linking tobacco smoking with depression. With prospective data, the study sheds new light on the temporal sequencing of tobacco smoking and depressed mood in late c ... Full text Open Access Link to item Cite

Panic attacks and suicide attempts in mid-adolescence.

Journal Article Am J Psychiatry · October 1999 Featured Publication OBJECTIVE: The aim of this study was to investigate the association of panic attacks and suicide attempts in a community-based sample of 13-14-year-old adolescents. METHOD: The data are from a survey of 1,580 students in an urban public school system locat ... Full text Open Access Link to item Cite

Influence of comorbid alcohol and psychiatric disorders on utilization of mental health services in the National Comorbidity Survey.

Journal Article Am J Psychiatry · August 1999 Featured Publication OBJECTIVE: This study sought to determine how comorbidity of psychiatric and substance abuse disorders affects the likelihood of using mental health services. METHOD: The analysis was based on data on adults aged 18-54 years in the National Comorbidity Sur ... Full text Open Access Link to item Cite

Tobacco smoking and other suspected antecedents of nonmedical psychostimulant use in the United States, 1995.

Journal Article Subst Use Misuse · July 1999 Featured Publication This study investigates the extent to which tobacco smoking is associated with the nonmedical use of psychostimulants and the temporal order of the age of first use for tobacco and psychostimulants within a nationally representative sample of United States ... Full text Open Access Link to item Cite