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Yuliya Vladimirovna Lokhnygina

Associate Professor of Biostatistics & Bioinformatics
Biostatistics & Bioinformatics, Division of Biostatistics
Duke Box 3850, Durham, NC 27710
200 Morris Street, 6126 200 Morris, Durham, NC 27701

Overview


Statistical methods in clinical trials, survival analysis, adaptive designs, adaptive treatment strategies, causal inference in observational studies, semiparametric inference

Current Duke Appointments & Affiliations


Associate Professor of Biostatistics & Bioinformatics · 2022 - Present Biostatistics & Bioinformatics, Division of Biostatistics, Biostatistics & Bioinformatics
Member in the Duke Clinical Research Institute · 2004 - Present Duke Clinical Research Institute, Institutes and Centers

Recent Scholarly Works


User-Directed vs Interruptive Real-Time Benefit Tools for Medication Changes in Primary Care.

Journal article JAMA Netw Open · June 1, 2026 IMPORTANCE: Real-time benefit tools (RTBTs) in the electronic health record (EHR) provide medication cost estimates and lower-cost alternatives. RTBT use leads to improved adherence and lower costs among patients with chronic conditions; however, clinician ... Full text Link to item Cite

Estimation and inference of the win ratio for two hierarchical endpoints subject to censoring and missing data.

Journal article J Biopharm Stat · May 11, 2026 The win ratio (WR) is a widely used metric to compare treatments in randomized clinical trials with hierarchically ordered endpoints. Counting-based approaches, such as Pocock's algorithm, are the standard for WR estimation. However, this algorithm treats ... Full text Link to item Cite

Worsening Kidney Function and Cardiovascular Outcomes in Type 2 Diabetes and Atherosclerotic Disease.

Journal article JACC Adv · March 2026 BACKGROUND: The bidirectional association between worsening kidney function (WKF) and cardiovascular outcomes in type 2 diabetes (T2D) patients with atherosclerotic cardiovascular disease (ASCVD) is unclear. OBJECTIVES: This study aimed to evaluate the bid ... Full text Link to item Cite
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Recent Grants


Liposomal Amphotericin B and Flucytosine Antifungal Strategies for Talaromycosis (LAmB-FAST) - R01

ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2031

Improving Neonatal health Through Rapid malaria testing in Early Pregnancy with high-sensitivity Diagnostics (INTREPiD)

ResearchStatistical Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2022 - 2027

Helping Patients Achieve Kidney Transplants through Health System Change

ResearchBiostatistician Investigator · Awarded by Wake Forest University Health Sciences · 2023 - 2026

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Education


North Carolina State University · 2004 Ph.D.
Cornell University · 2001 M.S.
Moscow Institute of Physics and Technology (Russia) · 1999 M.S.