Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Ph.D., North Carolina State University 2004
  • M.S., Cornell University 2001
  • M.S., Moscow Institute of Physics and Technology 1999
• 

  Duke Appointment History

  • Assistant Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2004 - 2014
  • Instructor, Temporary of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2004
• Research
• 

  Selected Grants

  • Prevention of Surgical Site Infection using Statistical Process Control Charts awarded by Agency for Healthcare Research and Quality 2015 - 2020
  • RFTOP #2018 Domain 2-B-0001 Base Period awarded by Centers for Disease Control and Prevention 2018 - 2020
  • Improving antibiotic use through implementation and evaluation of Core Elements of Hospital Antibiotic Stewardship Programs (Domain 2) awarded by Centers for Disease Control and Prevention 2016 - 2019
  • Administrative Claims-based Efficiencies for the Advancement of Regulatory Sciences awarded by Burroughs Wellcome Fund 2014 - 2019
  • Metals in the Trial to Assess Chelation Therapy 2 (TACT2M) awarded by Mount Sinai School of Medicine 2016 - 2019
  • BRIDGE DCC awarded by National Institutes of Health 2008 - 2017
  • A Four-arm Prospective, Multicenter Study to Assess the Clinical Efficacy, Effectiveness, and Feasibility of Enhanced Ro awarded by Centers for Disease Control and Prevention 2011 - 2016
  • Evaluation of the Efficacy of Personal Protective Equipment and Antiseptic Impregnated Clothing in Reducing Exposure of Health Care Personnel to Acquisition and Transmission of Viral and Bacterial Pat awarded by Centers for Disease Control and Prevention 2015 - 2016
  • IPA-Yuliya Lokhnygina awarded by Durham Veterans Affairs Medical Center 2012 - 2014
  • PROPRANOLOL AS ANTI-ADHESIVE THERAPY IN SCD awarded by National Institutes of Health 2010 - 2012
  • Cohort Study of Patients at Risk for C. diff Infections awarded by Centers for Disease Control and Prevention 2011 - 2012
  • STICH Statistics and Data Coordinating Center awarded by National Institutes of Health 2002 - 2011
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Guimarães, Patrícia O., Eric D. Peterson, Susanna R. Stevens, Yuliya Lokhnygina, Jennifer B. Green, Darren K. McGuire, Rury R. Holman, and Renato D. Lopes. “Antithrombotic treatment gap among patients with atrial fibrillation and type 2 diabetes..” Int J Cardiol, April 30, 2019. https://doi.org/10.1016/j.ijcard.2019.04.085.
       Full Text  Link to Item
    • Sharma, Abhinav, Jie-Lena Sun, Yuliya Lokhnygina, Matthew T. Roe, Tariq Ahmad, Nihar R. Desai, and Michael A. Blazing. “Patient Phenotypes, Cardiovascular Risk, and Ezetimibe Treatment in Patients After Acute Coronary Syndromes (from IMPROVE-IT)..” The American Journal of Cardiology 123, no. 8 (April 2019): 1193–1201. https://doi.org/10.1016/j.amjcard.2019.01.034.
       Full Text
    • Doll, Jacob A., W Schuyler Jones, Yuliya Lokhnygina, Sara Culpepper, Robin L. Parks, Christy Calhoun, David H. Au, and Manesh R. Patel. “PREPARED Study: A Study of Shared Decision-Making for Coronary Artery Disease..” Circulation. Cardiovascular Quality and Outcomes 12, no. 2 (February 2019). https://doi.org/10.1161/circoutcomes.118.005244.
       Full Text
    • Navar, Ann Marie, Matthew T. Roe, Jennifer A. White, Christopher P. Cannon, Yuliya Lokhnygina, L Kristin Newby, Robert P. Giugliano, et al. “Medication Discontinuation in the IMPROVE-IT Trial..” Circulation. Cardiovascular Quality and Outcomes 12, no. 1 (January 2019). https://doi.org/10.1161/circoutcomes.118.005041.
       Full Text
    • Ambrosy, Andrew P., Lukasz P. Cerbin, Marat Fudim, Robert M. Clare, Yuliya Lokhnygina, Eugene Braunwald, Robert M. Califf, et al. “Natural History of Patients Postacute Coronary Syndrome Based on Heart Failure Status..” The American Journal of Cardiology 122, no. 9 (November 2018): 1451–58. https://doi.org/10.1016/j.amjcard.2018.07.034.
       Full Text
    • Mentz, Robert J., M Angelyn Bethel, Peter Merrill, Yuliya Lokhnygina, John B. Buse, Juliana C. Chan, João S. Felício, et al. “Effect of Once-Weekly Exenatide on Clinical Outcomes According to Baseline Risk in Patients With Type 2 Diabetes Mellitus: Insights From the EXSCEL Trial..” Journal of the American Heart Association 7, no. 19 (October 2018). https://doi.org/10.1161/JAHA.118.009304.
       Full Text
    • Anderson, Deverick J., Rebekah W. Moehring, David J. Weber, Sarah S. Lewis, Luke F. Chen, J Conrad Schwab, Paul Becherer, et al. “Effectiveness of targeted enhanced terminal room disinfection on hospital-wide acquisition and infection with multidrug-resistant organisms and Clostridium difficile: a secondary analysis of a multicentre cluster randomised controlled trial with crossover design (BETR Disinfection)..” Lancet Infect Dis 18, no. 8 (August 2018): 845–53. https://doi.org/10.1016/S1473-3099(18)30278-0.
       Full Text  Link to Item
    • Davis, Timothy M. E., Hillary Mulder, Yuliya Lokhnygina, Pablo Aschner, Lee-Ming Chuang, Carlos A. Raffo Grado, Eberhard Standl, Eric D. Peterson, Rury R. Holman, and Rury R. TECOS Study Group. “Effect of race on the glycaemic response to sitagliptin: Insights from the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS)..” Diabetes, Obesity & Metabolism 20, no. 6 (June 2018): 1427–34. https://doi.org/10.1111/dom.13242.
       Full Text
    • Husain, Aatif M., Jong W. Lee, Bradley J. Kolls, Lawrence J. Hirsch, Jonathan J. Halford, Puneet K. Gupta, Yafa Minazad, et al. “Randomized trial of lacosamide versus fosphenytoin for nonconvulsive seizures..” Annals of Neurology 83, no. 6 (June 2018): 1174–85. https://doi.org/10.1002/ana.25249.
       Full Text
    • Moehring, Rebekah W., Elizabeth S. Dodds Ashley, Xinru Ren, Yuliya Lokhnygina, Arthur W. Baker, Travis M. Jones, Sarah S. Lewis, Daniel J. Sexton, Deverick J. Anderson, and Deverick J. Centers for Disease Control and Prevention Epicenters Program. “Denominator Matters in Estimating Antimicrobial Use: A Comparison of Days Present and Patient Days..” Infection Control and Hospital Epidemiology 39, no. 5 (May 2018): 612–15. https://doi.org/10.1017/ice.2018.54.
       Full Text
    • Anderson, Deverick J., Lauren P. Knelson, Rebekah W. Moehring, Sarah S. Lewis, David J. Weber, Luke F. Chen, Patricia F. Triplett, et al. “Implementation Lessons Learned From the Benefits of Enhanced Terminal Room (BETR) Disinfection Study: Process and Perceptions of Enhanced Disinfection with Ultraviolet Disinfection Devices..” Infection Control and Hospital Epidemiology 39, no. 2 (February 2018): 157–63. https://doi.org/10.1017/ice.2017.268.
       Full Text
    • Bethel, M Angelyn, Rishi A. Patel, Peter Merrill, Yuliya Lokhnygina, John B. Buse, Robert J. Mentz, Neha J. Pagidipati, et al. “Cardiovascular outcomes with glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes: a meta-analysis..” Lancet Diabetes Endocrinol 6, no. 2 (February 2018): 105–13. https://doi.org/10.1016/S2213-8587(17)30412-6.
       Full Text  Link to Item
    • Kochar, Ajar, Anne S. Hellkamp, Yuliya Lokhnygina, W Schuyler Jones, Richard C. Becker, Scott D. Berkowitz, Günter Breithardt, et al. “Efficacy and safety of rivaroxaban compared with warfarin in patients with carotid artery disease and nonvalvular atrial fibrillation: Insights from the ROCKET AF trial..” Clinical Cardiology 41, no. 1 (January 2018): 39–45. https://doi.org/10.1002/clc.22846.
       Full Text
    • Limkakeng, Alexander T., J Clancy Leahy, S Michelle Griffin, Yuliya Lokhnygina, Elias Jaffa, Robert H. Christenson, and L Kristin Newby. “Provocative biomarker stress test: stress-delta N-terminal pro-B type natriuretic peptide..” Open Heart 5, no. 2 (January 2018). https://doi.org/10.1136/openhrt-2018-000847.
       Full Text  Open Access Copy
    • Sharma, Abhinav, Jennifer B. Green, Allison Dunning, Yuliya Lokhnygina, Sana M. Al-Khatib, Renato D. Lopes, John B. Buse, et al. “Causes of Death in a Contemporary Cohort of Patients With Type 2 Diabetes and Atherosclerotic Cardiovascular Disease: Insights From the TECOS Trial..” Diabetes Care 40, no. 12 (December 2017): 1763–70. https://doi.org/10.2337/dc17-1091.
       Full Text  Link to Item
    • Navar, Ann Marie, Dianne S. Gallup, Yuliya Lokhnygina, Jennifer B. Green, Darren K. McGuire, Paul W. Armstrong, John B. Buse, et al. “Hypertension Control in Adults With Diabetes Mellitus and Recurrent Cardiovascular Events: Global Results From the Trial Evaluating Cardiovascular Outcomes With Sitagliptin..” Hypertension (Dallas, Tex. : 1979) 70, no. 5 (November 2017): 907–14. https://doi.org/10.1161/HYPERTENSIONAHA.117.09482.
       Full Text
    • Anderson, Deverick J., Rachel Addison, Yuliya Lokhnygina, Bobby Warren, Batu Sharma-Kuinkel, Laura J. Rojas, Susan D. Rudin, et al. “The Antimicrobial Scrub Contamination and Transmission (ASCOT) Trial: A Three-Arm, Blinded, Randomized Controlled Trial With Crossover Design to Determine the Efficacy of Antimicrobial-Impregnated Scrubs in Preventing Healthcare Provider Contamination..” Infection Control and Hospital Epidemiology 38, no. 10 (October 2017): 1147–54. https://doi.org/10.1017/ice.2017.181.
       Full Text
    • Stanifer, John W., David M. Charytan, Jennifer White, Yuliya Lokhnygina, Christopher P. Cannon, Matthew T. Roe, and Michael A. Blazing. “Benefit of Ezetimibe Added to Simvastatin in Reduced Kidney Function..” Journal of the American Society of Nephrology : Jasn 28, no. 10 (October 2017): 3034–43. https://doi.org/10.1681/ASN.2016090957.
       Full Text  Open Access Copy
    • Holman, Rury R., M Angelyn Bethel, Robert J. Mentz, Vivian P. Thompson, Yuliya Lokhnygina, John B. Buse, Juliana C. Chan, et al. “Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes..” N Engl J Med 377, no. 13 (September 28, 2017): 1228–39. https://doi.org/10.1056/NEJMoa1612917.
       Full Text  Link to Item
    • Fanaroff, Alexander C., Matthew T. Roe, Robert M. Clare, Yuliya Lokhnygina, Ann Marie Navar, Robert P. Giugliano, Stephen D. Wiviott, Andrew M. Tershakovec, Eugene Braunwald, and Michael A. Blazing. “Competing Risks of Cardiovascular Versus Noncardiovascular Death During Long-Term Follow-Up After Acute Coronary Syndromes..” Journal of the American Heart Association 6, no. 9 (September 18, 2017). https://doi.org/10.1161/JAHA.117.005840.
       Full Text
    • Pagidipati, Neha J., Ann Marie Navar, Karen S. Pieper, Jennifer B. Green, M Angelyn Bethel, Paul W. Armstrong, Robert G. Josse, et al. “Secondary Prevention of Cardiovascular Disease in Patients With Type 2 Diabetes Mellitus: International Insights From the TECOS Trial (Trial Evaluating Cardiovascular Outcomes With Sitagliptin)..” Circulation 136, no. 13 (September 2017): 1193–1203. https://doi.org/10.1161/CIRCULATIONAHA.117.027252.
       Full Text
    • Sun, Yihong, Dayi Hu, Susanna Stevens, Yuliya Lokhnygina, Richard C. Becker, Scott D. Berkowitz, Günter Breithardt, et al. “Efficacy and safety of rivaroxaban versus warfarin in patients from mainland China with nonvalvular atrial fibrillation: A subgroup analysis from the ROCKET AF trial..” Thrombosis Research 156 (August 2017): 184–90. https://doi.org/10.1016/j.thromres.2017.04.010.
       Full Text
    • Balla, Somasekhara R., Derek D. Cyr, Yuliya Lokhnygina, Richard C. Becker, Scott D. Berkowitz, Günter Breithardt, Keith A. A. Fox, et al. “Relation of Risk of Stroke in Patients With Atrial Fibrillation to Body Mass Index (from Patients Treated With Rivaroxaban and Warfarin in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation Trial)..” The American Journal of Cardiology 119, no. 12 (June 2017): 1989–96. https://doi.org/10.1016/j.amjcard.2017.03.028.
       Full Text
    • Harskamp, Ralf E., Robert M. Clare, Giuseppe Ambrosio, Claes Held, Yuliya Lokhnygina, David J. Moliterno, Harvey D. White, et al. “Use of thienopyridine prior to presentation with non-ST-segment elevation acute coronary syndrome and association with safety and efficacy of vorapaxar: insights from the TRACER trial..” European Heart Journal. Acute Cardiovascular Care 6, no. 2 (March 2017): 155–63. https://doi.org/10.1177/2048872616633880.
       Full Text
    • Lindner, Samuel M., Christopher B. Fordyce, Anne S. Hellkamp, Yuliya Lokhnygina, Jonathan P. Piccini, Günter Breithardt, Kenneth W. Mahaffey, et al. “Treatment Consistency Across Levels of Baseline Renal Function With Rivaroxaban or Warfarin: A ROCKET AF (Rivaroxaban Once-Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation) Analysis..” Circulation 135, no. 10 (March 2017): 1001–3. https://doi.org/10.1161/circulationaha.116.024666.
       Full Text
    • Valgimigli, Marco, Francesco Costa, Yuliya Lokhnygina, Robert M. Clare, Lars Wallentin, David J. Moliterno, Paul W. Armstrong, et al. “Trade-off of myocardial infarction vs. bleeding types on mortality after acute coronary syndrome: lessons from the Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRACER) randomized trial..” European Heart Journal 38, no. 11 (March 2017): 804–10. https://doi.org/10.1093/eurheartj/ehw525.
       Full Text
    • Anderson, Deverick J., Luke F. Chen, David J. Weber, Rebekah W. Moehring, Sarah S. Lewis, Patricia F. Triplett, Michael Blocker, et al. “Enhanced terminal room disinfection and acquisition and infection caused by multidrug-resistant organisms and Clostridium difficile (the Benefits of Enhanced Terminal Room Disinfection study): a cluster-randomised, multicentre, crossover study..” Lancet (London, England) 389, no. 10071 (February 2017): 805–14. https://doi.org/10.1016/S0140-6736(16)31588-4.
       Full Text
    • Buse, John B., M Angelyn Bethel, Jennifer B. Green, Susanna R. Stevens, Yuliya Lokhnygina, Pablo Aschner, Carlos Raffo Grado, et al. “Pancreatic Safety of Sitagliptin in the TECOS Study..” Diabetes Care 40, no. 2 (February 2017): 164–70. https://doi.org/10.2337/dc15-2780.
       Full Text
    • Blazing, Michael A., Robert P. Giugliano, James A. de Lemos, Christopher P. Cannon, Andrew Tonkin, Christie M. Ballantyne, Basil S. Lewis, et al. “On-treatment analysis of the Improved Reduction of Outcomes: Vytorin Efficacy International Trial (IMPROVE-IT)..” American Heart Journal 182 (December 2016): 89–96. https://doi.org/10.1016/j.ahj.2016.09.004.
       Full Text
    • Shah, Rohan, Anne Hellkamp, Yuliya Lokhnygina, Richard C. Becker, Scott D. Berkowitz, Günter Breithardt, Werner Hacke, et al. “Use of concomitant aspirin in patients with atrial fibrillation: Findings from the ROCKET AF trial..” American Heart Journal 179 (September 2016): 77–86. https://doi.org/10.1016/j.ahj.2016.05.019.
       Full Text
    • Åkerblom, Axel, Robert M. Clare, Yuliya Lokhnygina, Lars Wallentin, Claes Held, Frans Van de Werf, David J. Moliterno, et al. “Albuminuria and cardiovascular events in patients with acute coronary syndromes: Results from the TRACER trial..” American Heart Journal 178 (August 2016): 1–8. https://doi.org/10.1016/j.ahj.2016.04.013.
       Full Text
    • Fordyce, Christopher B., Anne S. Hellkamp, Yuliya Lokhnygina, Samuel M. Lindner, Jonathan P. Piccini, Richard C. Becker, Scott D. Berkowitz, et al. “On-Treatment Outcomes in Patients With Worsening Renal Function With Rivaroxaban Compared With Warfarin: Insights From ROCKET AF..” Circulation 134, no. 1 (July 5, 2016): 37–47. https://doi.org/10.1161/CIRCULATIONAHA.116.021890.
       Full Text  Link to Item
    • Breithardt, Günter, Helmut Baumgartner, Scott D. Berkowitz, Anne S. Hellkamp, Jonathan P. Piccini, Yuliya Lokhnygina, Jonathan L. Halperin, et al. “Native valve disease in patients with non-valvular atrial fibrillation on warfarin or rivaroxaban..” Heart (British Cardiac Society) 102, no. 13 (July 2016): 1036–43. https://doi.org/10.1136/heartjnl-2015-308120.
       Full Text
    • Lakey, Wanda C., Nicole G. Greyshock, Carly E. Kelley, Mohammad A. Siddiqui, Umar Ahmad, Yuliya V. Lokhnygina, and John R. Guyton. “Statin intolerance in a referral lipid clinic..” Journal of Clinical Lipidology 10, no. 4 (July 2016): 870-879.e3. https://doi.org/10.1016/j.jacl.2016.03.004.
       Full Text
    • Li, Fan, Yuliya Lokhnygina, David M. Murray, Patrick J. Heagerty, and Elizabeth R. DeLong. “An evaluation of constrained randomization for the design and analysis of group-randomized trials..” Stat Med 35, no. 10 (May 10, 2016): 1565–79. https://doi.org/10.1002/sim.6813.
       Full Text  Link to Item
    • McGuire, Darren K., Frans Van de Werf, Paul W. Armstrong, Eberhard Standl, Joerg Koglin, Jennifer B. Green, M Angelyn Bethel, et al. “Association Between Sitagliptin Use and Heart Failure Hospitalization and Related Outcomes in Type 2 Diabetes Mellitus: Secondary Analysis of a Randomized Clinical Trial..” Jama Cardiology 1, no. 2 (May 2016): 126–35. https://doi.org/10.1001/jamacardio.2016.0103.
       Full Text
    • Farber, S Harrison, Jeffrey Hatef, Jing L. Han, Andrew H. Marky, Jichun Xie, Kevin Huang, Terence Verla, Yuliya Lokhnygina, Timothy A. Collins, and Shivanand P. Lad. “Implantable Neurostimulation for Headache Disorders: Effect on Healthcare Utilization and Expenditures..” Neuromodulation : Journal of the International Neuromodulation Society 19, no. 3 (April 2016): 319–28. https://doi.org/10.1111/ner.12393.
       Full Text
    • Hess, Paul L., Daniel M. Wojdyla, Sana M. Al-Khatib, Yuliya Lokhnygina, Lars Wallentin, Paul W. Armstrong, Matthew T. Roe, et al. “Sudden Cardiac Death After Non-ST-Segment Elevation Acute Coronary Syndrome..” Jama Cardiology 1, no. 1 (April 2016): 73–79. https://doi.org/10.1001/jamacardio.2015.0359.
       Full Text
    • Murphy, Sabina A., Christopher P. Cannon, Michael A. Blazing, Robert P. Giugliano, Jennifer A. White, Yuliya Lokhnygina, Craig Reist, et al. “Reduction in Total Cardiovascular Events With Ezetimibe/Simvastatin Post-Acute Coronary Syndrome: The IMPROVE-IT Trial..” Journal of the American College of Cardiology 67, no. 4 (February 2016): 353–61. https://doi.org/10.1016/j.jacc.2015.10.077.
       Full Text
    • Halim, Sharif A., Robert M. Clare, L Kristin Newby, Yuliya Lokhnygina, Marc J. Schweiger, Arnoud W. Hof, Judith S. Hochman, et al. “Frequency, clinical and angiographic characteristics, and outcomes of high-risk non-ST-segment elevation acute coronary syndromes patients with left circumflex culprit lesions..” Int J Cardiol 203 (January 15, 2016): 708–13. https://doi.org/10.1016/j.ijcard.2015.11.036.
       Full Text  Link to Item
    • Petraglia, Frank W., S Harrison Farber, Jing L. Han, Terence Verla, John Gallis, Yuliya Lokhnygina, Beth Parente, Patrick Hickey, Dennis A. Turner, and Shivanand P. Lad. “Comparison of Bilateral vs. Staged Unilateral Deep Brain Stimulation (DBS) in Parkinson's Disease in Patients Under 70 Years of Age..” Neuromodulation : Journal of the International Neuromodulation Society 19, no. 1 (January 2016): 31–37. https://doi.org/10.1111/ner.12351.
       Full Text
    • Bansilal, Sameer, Zachary Bloomgarden, Jonathan L. Halperin, Anne S. Hellkamp, Yuliya Lokhnygina, Manesh R. Patel, Richard C. Becker, et al. “Efficacy and safety of rivaroxaban in patients with diabetes and nonvalvular atrial fibrillation: the Rivaroxaban Once-daily, Oral, Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF Trial)..” Am Heart J 170, no. 4 (October 2015): 675-682.e8. https://doi.org/10.1016/j.ahj.2015.07.006.
       Full Text  Link to Item
    • Nicolau, Jose Carlos, Deepak L. Bhatt, Matthew T. Roe, Yuliya Lokhnygina, Benjamin Neely, Ramón Corbalán, José L. Leiva-Pons, et al. “Concomitant proton-pump inhibitor use, platelet activity, and clinical outcomes in patients with acute coronary syndromes treated with prasugrel versus clopidogrel and managed without revascularization: insights from the Targeted Platelet Inhibition to Clarify the Optimal Strategy to Medically Manage Acute Coronary Syndromes trial..” American Heart Journal 170, no. 4 (October 2015): 683-694.e3. https://doi.org/10.1016/j.ahj.2015.05.017.
       Full Text
    • Daneshmand, Mani A., Arun Krishnamoorthy, Marc D. Samsky, G Michael Felker, John A. Pura, Yuliya Lokhnygina, Adrian F. Hernandez, et al. “Comparison of 2-Year Outcomes of Extended Criteria Cardiac Transplantation Versus Destination Left Ventricular Assist Device Therapy Using Continuous Flow..” The American Journal of Cardiology 116, no. 4 (August 2015): 573–79. https://doi.org/10.1016/j.amjcard.2015.05.016.
       Full Text
    • Wieslander, Björn, Robin Nijveldt, Igor Klem, Yuliya Lokhnygina, John Pura, Galen S. Wagner, Martin Ugander, and Brett D. Atwater. “Evaluation of Selvester QRS score for use in presence of conduction abnormalities in a broad population..” Am Heart J 170, no. 2 (August 2015): 346–52. https://doi.org/10.1016/j.ahj.2015.05.005.
       Full Text  Link to Item
    • Washam, Jeffrey B., Susanna R. Stevens, Yuliya Lokhnygina, Jonathan L. Halperin, Günter Breithardt, Daniel E. Singer, Kenneth W. Mahaffey, et al. “Digoxin use in patients with atrial fibrillation and adverse cardiovascular outcomes: a retrospective analysis of the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF)..” Lancet 385, no. 9985 (June 13, 2015): 2363–70. https://doi.org/10.1016/S0140-6736(14)61836-5.
       Full Text  Link to Item
    • Bagai, Akshay, Zhen Huang, Yuliya Lokhnygina, Robert A. Harrington, Paul W. Armstrong, John Strony, Harvey D. White, et al. “Magnitude of troponin elevation and long-term clinical outcomes in acute coronary syndrome patients treated with and without revascularization..” Circulation. Cardiovascular Interventions 8, no. 6 (June 2015). https://doi.org/10.1161/circinterventions.115.002314.
       Full Text
    • Cornel, Jan H., Pierluigi Tricoci, Yuliya Lokhnygina, David J. Moliterno, Lars Wallentin, Paul W. Armstrong, Philip E. Aylward, et al. “Glycoprotein IIb/IIIa Receptor Inhibitors in Combination With Vorapaxar, a Platelet Thrombin Receptor Antagonist, Among Patients With Non-ST-Segment Elevation Acute Coronary Syndromes (from the TRACER Trial)..” The American Journal of Cardiology 115, no. 10 (May 2015): 1325–32. https://doi.org/10.1016/j.amjcard.2015.02.043.
       Full Text
    • Verla, Terence, Andrew Marky, Harrison Farber, Frank W. Petraglia, John Gallis, Yuliya Lokhnygina, Beth Parente, Patrick Hickey, Dennis A. Turner, and Shivanand P. Lad. “Impact of advancing age on post-operative complications of deep brain stimulation surgery for essential tremor..” Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia 22, no. 5 (May 2015): 872–76. https://doi.org/10.1016/j.jocn.2014.11.005.
       Full Text
    • Singer, Daniel E., Anne S. Hellkamp, Zhong Yuan, Yuliya Lokhnygina, Manesh R. Patel, Jonathan P. Piccini, Graeme J. Hankey, et al. “Alternative calculations of individual patient time in therapeutic range while taking warfarin: results from the ROCKET AF trial..” Journal of the American Heart Association 4, no. 3 (March 3, 2015). https://doi.org/10.1161/JAHA.114.001349.
       Full Text
    • Bakal, Jeffrey A., Matthew T. Roe, E Magnus Ohman, Shaun G. Goodman, Keith A. A. Fox, Yinggan Zheng, Cynthia M. Westerhout, et al. “Applying novel methods to assess clinical outcomes: insights from the TRILOGY ACS trial..” European Heart Journal 36, no. 6 (February 2015): 385-92a. https://doi.org/10.1093/eurheartj/ehu262.
       Full Text
    • Huang, Kevin T., Joel Martin, Andrew Marky, Gustavo Chagoya, Jeff Hatef, Matthew A. Hazzard, Steven M. Thomas, Yuliya Lokhnygina, and Shivanand P. Lad. “A national survey of spinal cord stimulation trial-to-permanent conversion rates..” Neuromodulation : Journal of the International Neuromodulation Society 18, no. 2 (February 2015): 133–39. https://doi.org/10.1111/ner.12199.
       Full Text
    • Steinberg, Benjamin A., Anne S. Hellkamp, Yuliya Lokhnygina, Manesh R. Patel, Günter Breithardt, Graeme J. Hankey, Richard C. Becker, et al. “Higher risk of death and stroke in patients with persistent vs. paroxysmal atrial fibrillation: results from the ROCKET-AF Trial..” European Heart Journal 36, no. 5 (February 2015): 288–96. https://doi.org/10.1093/eurheartj/ehu359.
       Full Text
    • Ahmad, Tariq, Teresa Wang, Emily C. O’Brien, Marc D. Samsky, John A. Pura, Yuliya Lokhnygina, Joseph G. Rogers, et al. “Effects of left ventricular assist device support on biomarkers of cardiovascular stress, fibrosis, fluid homeostasis, inflammation, and renal injury..” Jacc Heart Fail 3, no. 1 (January 2015): 30–39. https://doi.org/10.1016/j.jchf.2014.06.013.
       Full Text  Link to Item
    • Cornel, J. H., P. Tricoci, Y. Lokhnygina, D. J. Moliterno, L. Wallentin, P. W. Armstrong, P. E. Aylward, et al. “Glycoprotein IIb/IIIa receptor inhibitors in combination with vorapaxar, a platelet thrombin receptor antagonist, among patients with non-ST-segment elevation acute coronary syndromes (from the TRACER trial).” American Journal of Cardiology 115, no. 10 (January 1, 2015): 1325–32. https://doi.org/10.1016/j.amjcard.2015.02.043.
       Full Text
    • Huang, K. T., J. Martin, A. Marky, G. Chagoya, J. Hatef, M. A. Hazzard, S. M. Thomas, Y. Lokhnygina, and S. P. Lad. “A national survey of spinal cord stimulation trial-to-permanent conversion rates.” Neuromodulation 18, no. 2 (January 1, 2015): 133–39. https://doi.org/10.1111/ner.12199.
       Full Text
    • Verla, T., A. Marky, H. Farber, F. W. Petraglia, J. Gallis, Y. Lokhnygina, B. Parente, P. Hickey, D. A. Turner, and S. P. Lad. “Impact of advancing age on post-operative complications of deep brain stimulation surgery for essential tremor.” Journal of Clinical Neuroscience 22, no. 5 (January 1, 2015): 872–76. https://doi.org/10.1016/j.jocn.2014.11.005.
       Full Text
    • Breithardt, Günter, Helmut Baumgartner, Scott D. Berkowitz, Anne S. Hellkamp, Jonathan P. Piccini, Susanna R. Stevens, Yuliya Lokhnygina, et al. “Clinical characteristics and outcomes with rivaroxaban vs. warfarin in patients with non-valvular atrial fibrillation but underlying native mitral and aortic valve disease participating in the ROCKET AF trial..” European Heart Journal 35, no. 47 (December 2014): 3377–85. https://doi.org/10.1093/eurheartj/ehu305.
       Full Text
    • Tricoci, Pierluigi, Yuliya Lokhnygina, Zhen Huang, Frans Van de Werf, Jan H. Cornel, Edmond Chen, Lars Wallentin, et al. “Vorapaxar with or without clopidogrel after non-ST-segment elevation acute coronary syndromes: results from the thrombin receptor antagonist for clinical event reduction in acute coronary syndrome trial..” American Heart Journal 168, no. 6 (December 2014): 869-77.e1. https://doi.org/10.1016/j.ahj.2014.09.002.
       Full Text
    • Babu, Ranjith, Steven Thomas, Matthew A. Hazzard, Yuliya V. Lokhnygina, Allan H. Friedman, Oren N. Gottfried, Robert E. Isaacs, et al. “Morbidity, mortality, and health care costs for patients undergoing spine surgery following the ACGME resident duty-hour reform: Clinical article..” Journal of Neurosurgery. Spine 21, no. 4 (October 2014): 502–15. https://doi.org/10.3171/2014.5.spine13283.
       Full Text
    • DeLong, Michael R., Kevin T. Huang, John Gallis, Yuliya Lokhnygina, Beth Parente, Patrick Hickey, Dennis A. Turner, and Shivanand P. Lad. “Effect of advancing age on outcomes of deep brain stimulation for Parkinson disease..” Jama Neurology 71, no. 10 (October 2014): 1290–95. https://doi.org/10.1001/jamaneurol.2014.1272.
       Full Text
    • Piccini, Jonathan P., Sana M. Al-Khatib, Daniel M. Wojdyla, Linda K. Shaw, John R. Horton, Yuliya Lokhnygina, Kevin J. Anstrom, et al. “Comparison of safety of sotalol versus amiodarone in patients with atrial fibrillation and coronary artery disease..” The American Journal of Cardiology 114, no. 5 (September 2014): 716–22. https://doi.org/10.1016/j.amjcard.2014.06.004.
       Full Text
    • Valgimigli, Marco, Pierluigi Tricoci, Zhen Huang, Philip E. Aylward, Paul W. Armstrong, Frans Van de Werf, Sergio Leonardi, et al. “Usefulness and safety of vorapaxar in patients with non-ST-segment elevation acute coronary syndrome undergoing percutaneous coronary intervention (from the TRACER Trial)..” The American Journal of Cardiology 114, no. 5 (September 2014): 665–73. https://doi.org/10.1016/j.amjcard.2014.05.054.
       Full Text
    • Piccini, Jonathan P., Jyotsna Garg, Manesh R. Patel, Yuliya Lokhnygina, Shaun G. Goodman, Richard C. Becker, Scott D. Berkowitz, et al. “Management of major bleeding events in patients treated with rivaroxaban vs. warfarin: results from the ROCKET AF trial..” Eur Heart J 35, no. 28 (July 21, 2014): 1873–80. https://doi.org/10.1093/eurheartj/ehu083.
       Full Text  Link to Item
    • White, Harvey D., Zhen Huang, Pierluigi Tricoci, Frans Van de Werf, Lars Wallentin, Yuliya Lokhnygina, David J. Moliterno, Philip E. Aylward, Kenneth W. Mahaffey, and Paul W. Armstrong. “Reduction in overall occurrences of ischemic events with vorapaxar: results from TRACER..” Journal of the American Heart Association 3, no. 4 (July 10, 2014). https://doi.org/10.1161/JAHA.114.001032.
       Full Text
    • Halperin, J. L., G. J. Hankey, D. M. Wojdyla, J. P. Piccini, Y. Lokhnygina, M. R. Patel, G. Breithardt, et al. “Efficacy and safety of rivaroxaban compared with warfarin among elderly patients with nonvalvular atrial fibrillation in the rivaroxaban once daily, oral, direct factor xa inhibition compared with vitamin k antagonism for prevention of stroke and embolism trial in atrial fibrillation (ROCKET AF).” Circulation 130, no. 2 (July 8, 2014): 138–46. https://doi.org/10.1161/CIRCULATIONAHA.113.005008.
       Full Text
    • Halperin, Jonathan L., Graeme J. Hankey, Daniel M. Wojdyla, Jonathan P. Piccini, Yuliya Lokhnygina, Manesh R. Patel, Günter Breithardt, et al. “Efficacy and safety of rivaroxaban compared with warfarin among elderly patients with nonvalvular atrial fibrillation in the Rivaroxaban Once Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF)..” Circulation 130, no. 2 (July 8, 2014): 138–46. https://doi.org/10.1161/CIRCULATIONAHA.113.005008.
       Full Text  Link to Item
    • Sherwood, M. W., J. D. Douketis, M. R. Patel, J. P. Piccini, A. S. Hellkamp, Y. Lokhnygina, A. C. Spyropoulos, et al. “Outcomes of temporary interruption of rivaroxaban compared with warfarin in patients with nonvalvular atrial fibrillation: Results from the rivaroxaban once daily, oral, direct factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF).” Circulation 129, no. 18 (May 6, 2014): 1850–59. https://doi.org/10.1161/CIRCULATIONAHA.113.005754.
       Full Text
    • Hankey, Graeme J., Susanna R. Stevens, Jonathan P. Piccini, Yuliya Lokhnygina, Kenneth W. Mahaffey, Jonathan L. Halperin, Manesh R. Patel, et al. “Intracranial hemorrhage among patients with atrial fibrillation anticoagulated with warfarin or rivaroxaban: the rivaroxaban once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation..” Stroke 45, no. 5 (May 2014): 1304–12. https://doi.org/10.1161/strokeaha.113.004506.
       Full Text
    • Sharma, Richa, Stephanie Macy, Kara Richardson, Yuliya Lokhnygina, and Daniel T. Laskowitz. “A blood-based biomarker panel to detect acute stroke..” Journal of Stroke and Cerebrovascular Diseases : The Official Journal of National Stroke Association 23, no. 5 (May 2014): 910–18. https://doi.org/10.1016/j.jstrokecerebrovasdis.2013.07.034.
       Full Text
    • Sherwood, Matthew W., James D. Douketis, Manesh R. Patel, Jonathan P. Piccini, Anne S. Hellkamp, Yuliya Lokhnygina, Alex C. Spyropoulos, et al. “Outcomes of temporary interruption of rivaroxaban compared with warfarin in patients with nonvalvular atrial fibrillation: results from the rivaroxaban once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation (ROCKET AF)..” Circulation 129, no. 18 (May 2014): 1850–59. https://doi.org/10.1161/CIRCULATIONAHA.113.005754.
       Full Text
    • Allen LaPointe, Nancy M., Yuliya Lokhnygina, Jacqueline Rimmler, Gillian D. Sanders, Eric D. Peterson, and Sana M. Al-Khatib. “Use Of Rate And Rhythm Control Drugs In Patients Younger Than 65 Years With Atrial Fibrillation..” Journal of Atrial Fibrillation 7, no. 1 (January 2014): 22–30.
    • Hankey, G. J., S. R. Stevens, J. P. Piccini, Y. Lokhnygina, K. W. Mahaffey, J. L. Halperin, M. R. Patel, et al. “Intracranial hemorrhage among patients with atrial fibrillation anticoagulated with warfarin or rivaroxaban: The rivaroxaban once daily, oral, direct factor xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation.” Stroke 45, no. 5 (January 1, 2014): 1304–12. https://doi.org/10.1161/STROKEAHA.113.004506.
       Full Text
    • Steinberg, B. A., A. S. Hellkamp, Y. Lokhnygina, J. L. Halperin, G. Breithardt, R. Passman, G. J. Hankey, et al. “Use and outcomes of antiarrhythmic therapy in patients with atrial fibrillation receiving oral anticoagulation: Results from the ROCKET AF trial.” Heart Rhythm 11, no. 6 (January 1, 2014): 925–32. https://doi.org/10.1016/j.hrthm.2014.03.006.
       Full Text
    • Tricoci, P., Y. Lokhnygina, Z. Huang, F. Van De Werf, J. H. Cornel, E. Chen, L. Wallentin, et al. “Vorapaxar with or without clopidogrel after non-ST-segment elevation acute coronary syndromes: Results from the thrombin receptor antagonist for clinical event reduction in acute coronary syndrome trial.” American Heart Journal 168, no. 6 (January 1, 2014): 869-877.e1. https://doi.org/10.1016/j.ahj.2014.09.002.
       Full Text
    • Allen LaPointe, Nancy M., Yuliya Lokhnygina, Gillian D. Sanders, Eric D. Peterson, and Sana M. Al-Khatib. “Adherence to guideline recommendations for antiarrhythmic drugs in atrial fibrillation..” Am Heart J 166, no. 5 (November 2013): 871–78. https://doi.org/10.1016/j.ahj.2013.08.010.
       Full Text  Link to Item
    • Allen Lapointe, N. M., Y. Lokhnygina, G. D. Sanders, E. D. Peterson, and S. M. Al-Khatib. “Adherence to guideline recommendations for antiarrhythmic drugs in atrial fibrillation.” American Heart Journal 166, no. 5 (November 1, 2013): 871–78. https://doi.org/10.1016/j.ahj.2013.08.010.
       Full Text
    • Bagai, Akshay, Jennifer A. White, Yuliya Lokhnygina, Robert P. Giugliano, Frans Van de Werf, Gilles Montalescot, Paul W. Armstrong, et al. “Routine early eptifibatide versus delayed provisional use at percutaneous coronary intervention in high-risk non-ST-segment elevation acute coronary syndromes patients: an analysis from the Early Glycoprotein IIb/IIIa Inhibition in Non-ST-Segment Elevation Acute Coronary Syndrome trial..” American Heart Journal 166, no. 3 (September 2013): 466–73. https://doi.org/10.1016/j.ahj.2013.05.019.
       Full Text
    • Piccini, Jonathan P., Susanna R. Stevens, Yuchiao Chang, Daniel E. Singer, Yuliya Lokhnygina, Alan S. Go, Manesh R. Patel, et al. “Response to letter regarding article, "renal dysfunction as a predictor of stroke and systemic embolism in patients with nonvalvular atrial fibrillation: validation of the R2CHADS2 index in the ROCKET AF (Rivaroxaban Once-Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation) and ATRIA (Anticoagulation and Risk Factors in Atrial Fibrillation) study cohorts"..” Circulation 128, no. 11 (September 2013): e172–73. https://doi.org/10.1161/circulationaha.113.004013.
       Full Text
    • Wiviott, Stephen D., Harvey D. White, E Magnus Ohman, Keith A. A. Fox, Paul W. Armstrong, Dorairaj Prabhakaran, Gail Hafley, et al. “Prasugrel versus clopidogrel for patients with unstable angina or non-ST-segment elevation myocardial infarction with or without angiography: a secondary, prespecified analysis of the TRILOGY ACS trial..” Lancet (London, England) 382, no. 9892 (August 2013): 605–13. https://doi.org/10.1016/s0140-6736(13)61451-8.
       Full Text
    • Chan, Mark Y., Jie-Lena Sun, L Kristin Newby, Yuliya Lokhnygina, Harvey D. White, David J. Moliterno, Pierre Théroux, et al. “Trends in clinical trials of non-ST-segment elevation acute coronary syndromes over 15 years..” International Journal of Cardiology 167, no. 2 (July 2013): 548–54. https://doi.org/10.1016/j.ijcard.2012.01.065.
       Full Text
    • Chiu, Stephanie J., Yuliya Lokhnygina, Adam M. Dubis, Alfredo Dubra, Joseph Carroll, Joseph A. Izatt, and Sina Farsiu. “Automatic cone photoreceptor segmentation using graph theory and dynamic programming..” Biomedical Optics Express 4, no. 6 (June 2013): 924–37. https://doi.org/10.1364/BOE.4.000924.
       Full Text
    • Leonardi, Sergio, Amanda Stebbins, Renato D. Lopes, Yuliya Lokhnygina, Meredith Todd, Deepak L. Bhatt, Gregg W. Stone, et al. “Quantification of the effect of clopidogrel on enzymatic infarct size related to a percutaneous coronary intervention in patients with acute coronary syndromes: insights from the CHAMPION percutaneous coronary intervention trial..” Coronary Artery Disease 24, no. 4 (June 2013): 321–27. https://doi.org/10.1097/mca.0b013e32835f2fbd.
       Full Text
    • Piccini, Jonathan P., Susanna R. Stevens, Yuliya Lokhnygina, Manesh R. Patel, Jonathan L. Halperin, Daniel E. Singer, Graeme J. Hankey, et al. “Outcomes after cardioversion and atrial fibrillation ablation in patients treated with rivaroxaban and warfarin in the ROCKET AF trial..” J Am Coll Cardiol 61, no. 19 (May 14, 2013): 1998–2006. https://doi.org/10.1016/j.jacc.2013.02.025.
       Full Text  Link to Item
    • Piccini, Jonathan P., Jennifer A. White, Rajendra H. Mehta, Yuliya Lokhnygina, Sana M. Al-Khatib, Pierluigi Tricoci, Robert M. Califf, et al. “Response to letter regarding article, “sustained ventricular tachycardia and ventricular fibrillation complicating non–ST-segment elevation acute coronary syndromes”..” Circulation 127, no. 20 (May 2013). https://doi.org/10.1161/circulationaha.112.147546.
       Full Text
    • Ozment, Caroline P., Lisa B. Mamo, Mary Lee Campbell, Yuliya Lokhnygina, Andrew J. Ghio, and Jennifer L. Turi. “Transfusion-related biologic effects and free hemoglobin, heme, and iron..” Transfusion 53, no. 4 (April 2013): 732–40. https://doi.org/10.1111/j.1537-2995.2012.03837.x.
       Full Text
    • Brooks, Audrey J., Yuliya Lokhnygina, Christina S. Meade, Jennifer Sharpe Potter, Donald A. Calsyn, and Shelly F. Greenfield. “Racial/ethnic differences in the rates and correlates of HIV risk behaviors among drug abusers..” The American Journal on Addictions 22, no. 2 (March 2013): 136–47. https://doi.org/10.1111/j.1521-0391.2013.00303.x.
       Full Text
    • Singer, Daniel E., Anne S. Hellkamp, Jonathan P. Piccini, Kenneth W. Mahaffey, Yuliya Lokhnygina, Guohua Pan, Jonathan L. Halperin, et al. “Impact of global geographic region on time in therapeutic range on warfarin anticoagulant therapy: data from the ROCKET AF clinical trial..” Journal of the American Heart Association 2, no. 1 (February 19, 2013). https://doi.org/10.1161/JAHA.112.000067.
       Full Text
    • Patel, Manesh R., Anne S. Hellkamp, Yuliya Lokhnygina, Jonathan P. Piccini, Zhongxin Zhang, Surya Mohanty, Daniel E. Singer, et al. “Outcomes of discontinuing rivaroxaban compared with warfarin in patients with nonvalvular atrial fibrillation: analysis from the ROCKET AF trial (Rivaroxaban Once-Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation)..” Journal of the American College of Cardiology 61, no. 6 (February 2013): 651–58. https://doi.org/10.1016/j.jacc.2012.09.057.
       Full Text
    • Saxon, Andrew J., Walter Ling, Maureen Hillhouse, Christie Thomas, Albert Hasson, Alfonso Ang, Geetha Doraimani, et al. “Buprenorphine/Naloxone and methadone effects on laboratory indices of liver health: a randomized trial..” Drug Alcohol Depend 128, no. 1–2 (February 1, 2013): 71–76. https://doi.org/10.1016/j.drugalcdep.2012.08.002.
       Full Text  Link to Item
    • Piccini, Jonathan P., Susanna R. Stevens, YuChiao Chang, Daniel E. Singer, Yuliya Lokhnygina, Alan S. Go, Manesh R. Patel, et al. “Renal dysfunction as a predictor of stroke and systemic embolism in patients with nonvalvular atrial fibrillation: validation of the R(2)CHADS(2) index in the ROCKET AF (Rivaroxaban Once-daily, oral, direct factor Xa inhibition Compared with vitamin K antagonism for prevention of stroke and Embolism Trial in Atrial Fibrillation) and ATRIA (AnTicoagulation and Risk factors In Atrial fibrillation) study cohorts..” Circulation 127, no. 2 (January 15, 2013): 224–32. https://doi.org/10.1161/CIRCULATIONAHA.112.107128.
       Full Text  Link to Item
    • Bagai, A., J. A. White, Y. Lokhnygina, R. P. Giugliano, F. V. D. Werf, G. Montalescot, P. W. Armstrong, et al. “Routine early eptifibatide versus delayed provisional use at percutaneous coronary intervention in high-risk non-ST-segment elevation acute coronary syndromes patients: An analysis from the Early Glycoprotein IIb/IIIa Inhibition in Non-ST-Segment Elevation Acute Coronary Syndrome trial.” American Heart Journal 166, no. 3 (2013): 466-473.e1. https://doi.org/10.1016/j.ahj.2013.05.019.
       Full Text
    • Chan, M. Y., J. L. Sun, L. K. Newby, Y. Lokhnygina, H. D. White, D. J. Moliterno, P. Théroux, et al. “Trends in clinical trials of non-ST-segment elevation acute coronary syndromes over 15 years.” International Journal of Cardiology 167, no. 2 (2013): 548–54. https://doi.org/10.1016/j.ijcard.2012.01.065.
       Full Text
    • Leonardi, S., A. Stebbins, R. D. Lopes, Y. Lokhnygina, M. Todd, D. L. Bhatt, G. W. Stone, et al. “Quantification of the effect of clopidogrel on enzymatic infarct size related to a percutaneous coronary intervention in patients with acute coronary syndromes: Insights from the CHAMPION percutaneous coronary intervention trial.” Coronary Artery Disease 24, no. 4 (2013): 321–27. https://doi.org/10.1097/MCA.0b013e32835f2fbd.
       Full Text
    • Lopes, Renato D., Yuliya Lokhnygina, Victor Hasselblad, Kristin L. Newby, Eric Yow, Christopher B. Granger, Paul W. Armstrong, et al. “Methods of creatine kinase-MB analysis to predict mortality in patients with myocardial infarction treated with reperfusion therapy..” Trials 14 (January 2013). https://doi.org/10.1186/1745-6215-14-123.
       Full Text  Open Access Copy
    • Ozment, C. P., L. B. Mamo, M. L. Campbell, Y. Lokhnygina, A. J. Ghio, and J. L. Turi. “Transfusion-related biologic effects and free hemoglobin, heme, and iron.” Transfusion 53, no. 4 (2013): 732–40. https://doi.org/10.1111/j.1537-2995.2012.03837.x.
       Full Text
    • Saxon, A. J., W. Ling, M. Hillhouse, C. Thomas, A. Hasson, A. Ang, G. Doraimani, et al. “Buprenorphine/Naloxone and methadone effects on laboratory indices of liver health: A randomized trial.” Drug and Alcohol Dependence 128, no. 1–2 (2013): 71–76. https://doi.org/10.1016/j.drugalcdep.2012.08.002.
       Full Text
    • Prakalapakorn, Sasapin G., Sharon F. Freedman, Yuliya Lokhnygina, Nandini G. Gandhi, Sandra Holgado, Bei Bei Chen, and Mays A. El-Dairi. “Longitudinal reproducibility of optical coherence tomography measurements in children..” Journal of Aapos : The Official Publication of the American Association for Pediatric Ophthalmology and Strabismus 16, no. 6 (December 2012): 523–28. https://doi.org/10.1016/j.jaapos.2012.08.011.
       Full Text
    • Roe, Matthew T., Paul W. Armstrong, Keith A. A. Fox, Harvey D. White, Dorairaj Prabhakaran, Shaun G. Goodman, Jan H. Cornel, et al. “Prasugrel versus clopidogrel for acute coronary syndromes without revascularization..” The New England Journal of Medicine 367, no. 14 (October 2012): 1297–1309. https://doi.org/10.1056/nejmoa1205512.
       Full Text
    • Piccini, Jonathan P., Jennifer A. White, Rajendra H. Mehta, Yuliya Lokhnygina, Sana M. Al-Khatib, Pierluigi Tricoci, Charles V. Pollack, et al. “Sustained ventricular tachycardia and ventricular fibrillation complicating non-ST-segment-elevation acute coronary syndromes..” Circulation 126, no. 1 (July 2012): 41–49. https://doi.org/10.1161/circulationaha.111.071860.
       Full Text
    • Jolicœur, E Marc, Micheal J. Sketch, Daniel M. Wojdyla, Sean P. Javaheri, Shravan Nosib, Yuliya Lokhnygina, Manesh R. Patel, Linda K. Shaw, and James E. Tcheng. “Percutaneous coronary interventions and cardiovascular outcomes for patients with chronic total occlusions..” Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions 79, no. 4 (March 2012): 603–12. https://doi.org/10.1002/ccd.23269.
       Full Text
    • Mills, James S., Kenneth W. Mahaffey, Yuliya Lokhnygina, Jose C. Nicolau, Witold Ruzyllo, Peter X. Adams, Thomas G. Todaro, Paul W. Armstrong, Christopher B. Granger, and Christopher B. CARDINAL investigators. “Prediction of enzymatic infarct size in ST-segment elevation myocardial infarction..” Coronary Artery Disease 23, no. 2 (March 2012): 118–25. https://doi.org/10.1097/mca.0b013e32834e4f8f.
       Full Text
    • Roe, Matthew T., Jennifer A. White, Padma Kaul, Pierluigi Tricoci, Yuliya Lokhnygina, Chadwick D. Miller, Arnoud W. van’t Hof, et al. “Regional patterns of use of a medical management strategy for patients with non-ST-segment elevation acute coronary syndromes: insights from the EARLY ACS Trial..” Circulation. Cardiovascular Quality and Outcomes 5, no. 2 (March 2012): 205–13. https://doi.org/10.1161/circoutcomes.111.962332.
       Full Text
    • Tricoci, Pierluigi, Zhen Huang, Claes Held, David J. Moliterno, Paul W. Armstrong, Frans Van de Werf, Harvey D. White, et al. “Thrombin-receptor antagonist vorapaxar in acute coronary syndromes..” The New England Journal of Medicine 366, no. 1 (January 2012): 20–33. https://doi.org/10.1056/nejmoa1109719.
       Full Text
    • Mahaffey, Kenneth W., Karen S. Pieper, Yuliya Lokhnygina, Robert M. Califf, Elliott M. Antman, Neal S. Kleiman, Shaun G. Goodman, et al. “The impact of postrandomization crossover of therapy in acute coronary syndromes care..” Circulation. Cardiovascular Quality and Outcomes 4, no. 2 (March 2011): 211–19. https://doi.org/10.1161/circoutcomes.109.853598.
       Full Text
    • Brooks, Audrey, Christina S. Meade, Jennifer Sharpe Potter, Yuliya Lokhnygina, Donald A. Calsyn, and Shelly F. Greenfield. “Gender differences in the rates and correlates of HIV risk behaviors among drug abusers..” Substance Use & Misuse 45, no. 14 (December 2010): 2444–69. https://doi.org/10.3109/10826084.2010.490928.
       Full Text
    • Hursting, Marcie J., Poulomi J. Pai, Julianna E. McCracken, Fred Hwang, Shayela Suvarna, Yuliya Lokhnygina, Nicholas Bandarenko, and Gowthami M. Arepally. “Platelet factor 4/heparin antibodies in blood bank donors..” American Journal of Clinical Pathology 134, no. 5 (November 2010): 774–80. https://doi.org/10.1309/AJCPG0MNR5NGKNFX.
       Full Text
    • Tillmann, Hans L., Alex J. Thompson, Keyur Patel, Manfred Wiese, Hannelore Tenckhoff, Hans D. Nischalke, Yuliya Lokhnygina, et al. “A polymorphism near IL28B is associated with spontaneous clearance of acute hepatitis C virus and jaundice..” Gastroenterology 139, no. 5 (November 2010): 1586-1592.e1. https://doi.org/10.1053/j.gastro.2010.07.005.
       Full Text  Link to Item
    • Chin, Chee Tang, Matthew T. Roe, Keith A. A. Fox, Dorairaj Prabhakaran, Debra A. Marshall, Helene Petitjean, Yuliya Lokhnygina, et al. “Study design and rationale of a comparison of prasugrel and clopidogrel in medically managed patients with unstable angina/non-ST-segment elevation myocardial infarction: the TaRgeted platelet Inhibition to cLarify the Optimal strateGy to medicallY manage Acute Coronary Syndromes (TRILOGY ACS) trial..” American Heart Journal 160, no. 1 (July 2010): 16-22.e1. https://doi.org/10.1016/j.ahj.2010.04.022.
       Full Text
    • Califf, Robert M., Yuliya Lokhnygina, Christopher P. Cannon, Michael E. Stepanavage, Carolyn H. McCabe, Thomas A. Musliner, Richard C. Pasternak, et al. “An update on the IMProved reduction of outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) design..” American Heart Journal 159, no. 5 (May 2010): 705–9. https://doi.org/10.1016/j.ahj.2010.03.004.
       Full Text
    • Unroe, Kathleen Tschantz, Trista Pfeiffenberger, Sarah Riegelhaupt, Jennifer Jastrzembski, Yuliya Lokhnygina, and Cathleen Colón-Emeric. “Inpatient medication reconciliation at admission and discharge: A retrospective cohort study of age and other risk factors for medication discrepancies..” The American Journal of Geriatric Pharmacotherapy 8, no. 2 (April 2010): 115–26. https://doi.org/10.1016/j.amjopharm.2010.04.002.
       Full Text
    • Carter-Edwards, Lori, Lori A. Bastian, Jessica Revels, Holiday Durham, Yuliya Lokhnygina, M Ahinee Amamoo, and Truls Ostbye. “Body image and body satisfaction differ by race in overweight postpartum mothers..” Journal of Women’S Health (2002) 19, no. 2 (February 2010): 305–11. https://doi.org/10.1089/jwh.2008.1238.
       Full Text  Open Access Copy
    • Railey, Mary Dell, Yuliya Lokhnygina, and Rebecca H. Buckley. “Long-term clinical outcome of patients with severe combined immunodeficiency who received related donor bone marrow transplants without pretransplant chemotherapy or post-transplant GVHD prophylaxis..” The Journal of Pediatrics 155, no. 6 (December 2009): 834-840.e1. https://doi.org/10.1016/j.jpeds.2009.07.049.
       Full Text
    • Hofmann, Alison M., Amy M. Scurlock, Stacie M. Jones, Kricia P. Palmer, Yuliya Lokhnygina, Pamela H. Steele, Janet Kamilaris, and A Wesley Burks. “Safety of a peanut oral immunotherapy protocol in children with peanut allergy..” The Journal of Allergy and Clinical Immunology 124, no. 2 (August 2009): 286-291.e6. https://doi.org/10.1016/j.jaci.2009.03.045.
       Full Text
    • Califf, Robert M., Yuliya Lokhnygina, Eric J. Velazquez, John J. V. McMurray, Jeffrey D. Leimberger, Eldrin F. Lewis, Rafael Diaz, Jan Murin, and Marc A. Pfeffer. “Usefulness of beta blockers in high-risk patients after myocardial infarction in conjunction with captopril and/or valsartan (from the VALsartan In Acute Myocardial Infarction [VALIANT] trial)..” The American Journal of Cardiology 104, no. 2 (July 2009): 151–57. https://doi.org/10.1016/j.amjcard.2009.03.020.
       Full Text
    • Kandzari, David E., Sunil V. Rao, Jeffrey W. Moses, Vladimir Dzavik, Bradley H. Strauss, Michael J. Kutryk, Charles A. Simonton, et al. “Clinical and angiographic outcomes with sirolimus-eluting stents in total coronary occlusions: the ACROSS/TOSCA-4 (Approaches to Chronic Occlusions With Sirolimus-Eluting Stents/Total Occlusion Study of Coronary Arteries-4) trial..” Jacc. Cardiovascular Interventions 2, no. 2 (February 2009): 97–106. https://doi.org/10.1016/j.jcin.2008.10.013.
       Full Text
    • Lokhnygina, Y., and A. A. Tsiatis. “Optimal two-stage group-sequential designs.” Journal of Statistical Planning and Inference 138, no. 2 (February 1, 2008): 489–99. https://doi.org/10.1016/j.jspi.2007.06.011.
       Full Text
    • Thomas, Kevin L., Sana M. Al-Khatib, Yuliya Lokhnygina, Scott D. Solomon, Lars Kober, John J. V. McMurray, Robert M. Califf, and Eric J. Velazquez. “Amiodarone use after acute myocardial infarction complicated by heart failure and/or left ventricular dysfunction may be associated with excess mortality..” American Heart Journal 155, no. 1 (January 2008): 87–93. https://doi.org/10.1016/j.ahj.2007.09.010.
       Full Text
    • Tricoci, Pierluigi, Yuliya Lokhnygina, Lisa G. Berdan, Steven R. Steinhubl, Dietrich C. Gulba, Harvey D. White, Neal S. Kleiman, et al. “Time to coronary angiography and outcomes among patients with high-risk non ST-segment elevation acute coronary syndromes: results from the SYNERGY trial..” Circulation 116, no. 23 (December 2007): 2669–77. https://doi.org/10.1161/circulationaha.107.690081.
       Full Text
    • Hasselblad, Vic, Wendy Gattis Stough, Monica R. Shah, Yuliya Lokhnygina, Christopher M. O’Connor, Robert M. Califf, and Kirkwood F. Adams. “Relation between dose of loop diuretics and outcomes in a heart failure population: results of the ESCAPE trial..” European Journal of Heart Failure 9, no. 10 (October 2007): 1064–69. https://doi.org/10.1016/j.ejheart.2007.07.011.
       Full Text
    • Mehta, Rajendra H., Adam B. Greenbaum, Yuliya Lokhnygina, L Kristin Newby, Frans Van De Werf, Paul W. Armstrong, Karen S. Pieper, Robert M. Califf, Christopher B. Granger, and Robert A. Harrington. “Timing of death and myocardial infarction in patients with non-ST elevation acute coronary syndromes: insights from randomized clinical trials..” Journal of Interventional Cardiology 20, no. 5 (October 2007): 299–306. https://doi.org/10.1111/j.1540-8183.2007.00277.x.
       Full Text
    • Lokhnygina, Yuliya, and Jeffrey D. Helterbrand. “Cox regression methods for two-stage randomization designs..” Biometrics 63, no. 2 (June 2007): 422–28. https://doi.org/10.1111/j.1541-0420.2007.00707.x.
       Full Text
    • Sampson, Uchechukwu K., Marc A. Pfeffer, John J. V. McMurray, Yuliya Lokhnygina, Harvey D. White, Scott D. Solomon, and Scott D. VALIANT Trial Investigators. “Predictors of stroke in high-risk patients after acute myocardial infarction: insights from the VALIANT Trial..” European Heart Journal 28, no. 6 (March 2007): 685–91. https://doi.org/10.1093/eurheartj/ehl197.
       Full Text
    • Barnhart, Huiman X., Yuliya Lokhnygina, Andrzej S. Kosinski, and Michael Haber. “Comparison of concordance correlation coefficient and coefficient of individual agreement in assessing agreement..” Journal of Biopharmaceutical Statistics 17, no. 4 (January 2007): 721–38. https://doi.org/10.1080/10543400701329497.
       Full Text
    • Hasselblad, V., Y. Lokhnygina, and M. W. Krucoff. “Discussion of: Statistical and regulatory issues with the application of propensity score analysis to nonrandomized medical device clinical studies.” Journal of Biopharmaceutical Statistics 17, no. 1 (January 1, 2007): 19–21. https://doi.org/10.1080/10543400601044725.
       Full Text
    • Hasselblad, V., and Y. Lokhnygina. “Tests for 2 × 2 tables in clinical trials.” Journal of Modern Applied Statistical Methods 6, no. 2 (January 1, 2007): 456–68. https://doi.org/10.22237/jmasm/1193890140.
       Full Text
    • Niewoehner, Dennis E., Yuliya Lokhnygina, Kathryn Rice, Ware G. Kuschner, Amir Sharafkhaneh, George A. Sarosi, Peter Krumpe, Karen Pieper, and Steven Kesten. “Risk indexes for exacerbations and hospitalizations due to COPD..” Chest 131, no. 1 (January 2007): 20–28. https://doi.org/10.1378/chest.06-1316.
       Full Text
    • White, Harvey D., Neal S. Kleiman, Kenneth W. Mahaffey, Yuliya Lokhnygina, Karen S. Pieper, Karen Chiswell, Marc Cohen, et al. “Efficacy and safety of enoxaparin compared with unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndrome undergoing percutaneous coronary intervention in the Superior Yield of the New Strategy of Enoxaparin, Revascularization and Glycoprotein IIb/IIIa Inhibitors (SYNERGY) trial..” American Heart Journal 152, no. 6 (December 2006): 1042–50. https://doi.org/10.1016/j.ahj.2006.08.002.
       Full Text
    • Lokhnygina, Y. “Discussion of the "Executive Summary of the PhRMA Working Group on adaptive designs in clinical drug development".” Journal of Biopharmaceutical Statistics 16, no. 3 (May 1, 2006): 287–88. https://doi.org/10.1080/10543400600609684.
       Full Text

  • Conference Papers

    • Washam, Jeffrey B., Anne S. Hellkamp, Yuliya Lokhnygina, Jonathan P. Piccini, Scott D. Berkowitz, Christopher C. Nessel, Richard C. Becker, et al. “Efficacy and Safety of Rivaroxaban Versus Warfarin in Patients Taking Nondihydropyridine Calcium Channel Blockers for Atrial Fibrillation (from the ROCKET AF Trial)..” In The American Journal of Cardiology, 120:588–94, 2017. https://doi.org/10.1016/j.amjcard.2017.05.026.
       Full Text
    • Farhan, Serdar, Robert M. Clare, Rudolf Jarai, Robert P. Giugliano, Yuliya Lokhnygina, Robert A. Harrington, L. Kristin Newby, and Kurt Huber. “Fasting glucose, NT-proBNP, treatment with eptifibatide, and outcomes in non-ST-segment elevation acute coronary syndromes: An analysis from EARLY ACS..” In International Journal of Cardiology, 232:264–70, 2017. https://doi.org/10.1016/j.ijcard.2017.01.007.
       Full Text
    • Ilowite, Norman T., Kristi Prather, Yuliya Lokhnygina, Laura E. Schanberg, Melissa Elder, Diana Milojevic, James W. Verbsky, et al. “Randomized, double-blind, placebo-controlled trial of the efficacy and safety of rilonacept in the treatment of systemic juvenile idiopathic arthritis..” In Arthritis & Rheumatology (Hoboken, N.J.), 66:2570–79, 2014. https://doi.org/10.1002/art.38699.
       Full Text
    • Piccini, J. P., A. S. Hellkamp, Y. Lokhnygina, M. R. Patel, F. E. Harrell, D. E. Singer, R. C. Becker, et al. “Relationship between time in therapeutic range and comparative treatment effect of rivaroxaban and warfarin: Results from the ROCKET AF trial.” In Journal of the American Heart Association, Vol. 3, 2014. https://doi.org/10.1161/JAHA.113.000521.
       Full Text

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.