Skip to main content
construction release_alert
Profile editing will be unavailable for Scholars@Duke profiles from June 11-24, 2026 as manual profile data entry transitions to Elements. More information about the transition.
cancel

Yuliya Vladimirovna Lokhnygina

Associate Professor of Biostatistics & Bioinformatics
Biostatistics & Bioinformatics, Division of Biostatistics
Duke Box 3850, Durham, NC 27710
200 Morris Street, 6126 200 Morris, Durham, NC 27701

Overview


Statistical methods in clinical trials, survival analysis, adaptive designs, adaptive treatment strategies, causal inference in observational studies, semiparametric inference

Current Appointments & Affiliations


Associate Professor of Biostatistics & Bioinformatics · 2022 - Present Biostatistics & Bioinformatics, Division of Biostatistics, Biostatistics & Bioinformatics
Member in the Duke Clinical Research Institute · 2004 - Present Duke Clinical Research Institute, Institutes and Centers

Recent Publications


Estimation and inference of the win ratio for two hierarchical endpoints subject to censoring and missing data.

Journal Article J Biopharm Stat · May 11, 2026 The win ratio (WR) is a widely used metric to compare treatments in randomized clinical trials with hierarchically ordered endpoints. Counting-based approaches, such as Pocock's algorithm, are the standard for WR estimation. However, this algorithm treats ... Full text Link to item Cite

Worsening Kidney Function and Cardiovascular Outcomes in Type 2 Diabetes and Atherosclerotic Disease.

Journal Article JACC Adv · March 2026 BACKGROUND: The bidirectional association between worsening kidney function (WKF) and cardiovascular outcomes in type 2 diabetes (T2D) patients with atherosclerotic cardiovascular disease (ASCVD) is unclear. OBJECTIVES: This study aimed to evaluate the bid ... Full text Link to item Cite

Treatment preferences for comorbid obesity and obstructive sleep apnea (PRO-CON OSA) survey: Patient and provider preferences for CPAP and/or tirzepatide.

Journal Article J Clin Sleep Med · February 23, 2026 PURPOSE: Approximately one of ten US adults has comorbid obesity and obstructive sleep apnea (COBOSA). Traditionally, sleep medicine management of COBOSA focused on continuous positive airway pressure (CPAP). Recently, tirzepatide (a once-weekly injection) ... Full text Link to item Cite
View All Publications

Recent Grants


Liposomal Amphotericin B and Flucytosine Antifungal Strategies for Talaromycosis (LAmB-FAST) - R01

ResearchCo Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2031

Improving Neonatal health Through Rapid malaria testing in Early Pregnancy with high-sensitivity Diagnostics (INTREPiD)

ResearchStatistical Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2022 - 2027

Helping Patients Achieve Kidney Transplants through Health System Change

ResearchBiostatistician Investigator · Awarded by Wake Forest University Health Sciences · 2023 - 2026

View All Grants

Education


North Carolina State University · 2004 Ph.D.
Cornell University · 2001 M.S.
Moscow Institute of Physics and Technology (Russia) · 1999 M.S.