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Yuliya Vladimirovna Lokhnygina

Associate Professor of Biostatistics & Bioinformatics
Biostatistics & Bioinformatics, Division of Biostatistics
Duke Box 3850, Durham, NC 27710
200 Morris Street, 6126 200 Morris, Durham, NC 27701

Overview


Statistical methods in clinical trials, survival analysis, adaptive designs, adaptive treatment strategies, causal inference in observational studies, semiparametric inference

Current Appointments & Affiliations


Associate Professor of Biostatistics & Bioinformatics · 2022 - Present Biostatistics & Bioinformatics, Division of Biostatistics, Biostatistics & Bioinformatics
Member in the Duke Clinical Research Institute · 2004 - Present Duke Clinical Research Institute, Institutes and Centers

Recent Publications


System Interventions to Achieve Early and Equitable Kidney Transplants (STEPS): Protocol for STEPS, a randomized comparative effectiveness clinical trial.

Journal Article Contemp Clin Trials · June 2025 The System Interventions to Achieve Early and Equitable Kidney Transplants Study (STEPS) is an ongoing pragmatic clinical trial investigating the effectiveness of an equitable and patient-centered approach to kidney care on equitable access to early kidney ... Full text Link to item Cite

Kidney function after nonmyeloablative hematopoietic cell transplant for sickle cell disease.

Journal Article Bone Marrow Transplant · May 2025 Hematopoietic cell transplantation (HCT) is potentially curative for patients with sickle cell disease (SCD). Both SCD and HCT cause kidney damage. This study analyzed data from 160 patients who received nonmyelablative HCT for SCD. Renal function was asse ... Full text Link to item Cite

Sample Size and Power Calculations With Win Measures Based on Hierarchical Endpoints.

Journal Article Stat Med · May 2025 Win measures, such as win ratio, win odds, net benefit, and desirability of outcome ranking (DOOR), have become popular approaches for the analysis of hierarchical endpoints in clinical studies. Sample size and power calculations with win measures based on ... Full text Link to item Cite
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Recent Grants


Liposomal Amphotericin B and Flucytosine Antifungal Strategies for Talaromycosis (LAmB-FAST) - R01

ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2031

An infection prevention dilemma: should we place patients with C. difficile colonization on contact precautions?

ResearchInvestigator · Awarded by Agency for Healthcare Research and Quality · 2024 - 2028

Improving Neonatal health Through Rapid malaria testing in Early Pregnancy with high-sensitivity Diagnostics (INTREPiD)

ResearchStatistical Investigator · Awarded by National Institutes of Health · 2022 - 2027

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Education, Training & Certifications


North Carolina State University · 2004 Ph.D.
Cornell University · 2001 M.S.
Moscow Institute of Physics and Technology (Russia) · 1999 M.S.