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Yuliya Vladimirovna Lokhnygina

Associate Professor of Biostatistics & Bioinformatics
Biostatistics & Bioinformatics, Division of Biostatistics
Duke Box 3850, Durham, NC 27710
200 Morris Street, 6126 200 Morris, Durham, NC 27701

Overview


Statistical methods in clinical trials, survival analysis, adaptive designs, adaptive treatment strategies, causal inference in observational studies, semiparametric inference

Current Appointments & Affiliations


Associate Professor of Biostatistics & Bioinformatics · 2022 - Present Biostatistics & Bioinformatics, Division of Biostatistics, Biostatistics & Bioinformatics
Member in the Duke Clinical Research Institute · 2004 - Present Duke Clinical Research Institute, Institutes and Centers

Recent Publications


Safety Outcomes from a Long-Term, Prospective Study of Sertraline Use in Children and Adolescents: The Sertraline Pediatric Registry for the Evaluation of Safety

Journal Article Journal of Child and Adolescent Psychopharmacology · January 1, 2025 Objectives: To describe the Sertraline Pediatric Registry for the Evaluation of Safety (SPRITES) safety results, including adverse events (AEs) (serious and nonserious, including suicide-related events) following long-term treatment with sertraline in chil ... Full text Cite

Postoperative outcomes after receipt of ertapenem antimicrobial prophylaxis for colon surgery: a multicenter retrospective cohort study.

Journal Article Infection control and hospital epidemiology · October 2024 ObjectiveTo evaluate postoperative outcomes among patients undergoing colon surgery who receive perioperative prophylaxis with ertapenem compared to other antibiotic regimens.Design and settingMulticenter retrospective cohort study among ... Full text Cite

IL-6 inhibition with clazakizumab in patients receiving maintenance dialysis: a randomized phase 2b trial.

Journal Article Nat Med · August 2024 Inflammation mediated by interleukin-6 (IL-6) is strongly associated with cardiovascular risk. Here we evaluated clazakizumab, a monoclonal antibody targeting the IL-6 ligand, in a phase 2b dose-finding study. Adults with cardiovascular disease and/or diab ... Full text Link to item Cite
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Recent Grants


Liposomal Amphotericin B and Flucytosine Antifungal Strategies for Talaromycosis (LAmB-FAST) - R01

ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2031

An infection prevention dilemma: should we place patients with C. difficile colonization on contact precautions?

ResearchInvestigator · Awarded by Agency for Healthcare Research and Quality · 2024 - 2028

Improving Neonatal health Through Rapid malaria testing in Early Pregnancy with high-sensitivity Diagnostics (INTREPiD)

ResearchStatistical Investigator · Awarded by National Institutes of Health · 2022 - 2027

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Education, Training & Certifications


North Carolina State University · 2004 Ph.D.
Cornell University · 2001 M.S.
Moscow Institute of Physics and Technology (Russia) · 1999 M.S.