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William Curtis Eward

Frank H. Bassett III, M. D. Associate Professor of Orthopaedic Surgery
Orthopaedic Surgery
Box 3312 DUMC, Durham, NC 27710
Dept. of Orthopaedic Surgery, Durham, NC 27710

Overview


I am an Orthopaedic Oncologist, with dual clinical degrees (MD and DVM).  I treat complex sarcomas in people and animals.  My laboratory studies comparative oncology - discoveries we can make about cancer by analyses across different species.

Office Hours


Although I am always happy for people to drop by, my office hours vary by week.  Please email me at w.eward@alumni.duke.edu.

Current Appointments & Affiliations


Frank H. Bassett III, M. D. Associate Professor of Orthopaedic Surgery · 2022 - Present Orthopaedic Surgery, Clinical Science Departments
Associate Professor of Orthopaedic Surgery · 2023 - Present Orthopaedic Surgery, Clinical Science Departments
Associate Professor of Pathology · 2022 - Present Pathology, Clinical Science Departments
Member of the Duke Cancer Institute · 2013 - Present Duke Cancer Institute, Institutes and Centers

In the News


Published February 28, 2025
Bass Connections Team Tackles Microplastics
Published January 13, 2020
What Cancer Researchers Are Learning in Helping Our Best Friends
Published April 1, 2016
Researchers turn to canine clinical trials to advance cancer therapies

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Recent Publications


Financial Toxicity among Survivors of Extremity and Pelvic Sarcoma: A Retrospective Study.

Journal Article Ann Surg Oncol · March 2026 BACKGROUND: Financial toxicity in oncology, defined as the economic burden and psychosocial distress of cancer care, has been associated with poor clinical outcomes. Despite high projected treatment costs, data on financial toxicity in patients with sarcom ... Full text Link to item Cite

Keratin-positive giant cell-rich tumor with HMGA::NCOR2 fusion in a 4-year-old.

Journal Article Skeletal Radiol · March 2026 Epiphyseal and metaphyseal bone lesions in pediatric patients are uncommon, and lesions that cross an open physis are even rarer. The differential diagnosis for such lesions consists of infection, giant cell tumor, and chondroblastoma. We describe a 4-year ... Full text Link to item Cite
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Recent Grants


Does the use of the reamer-irrigator-aspirator (RIA) during prophylactic intramedullary nailing attenuate the rise of circulating tumor cells?

Clinical TrialPrincipal Investigator · Awarded by Medical Device Business Services, Inc. · 2025 - 2030

XPO1 and proteasome inhibition as a novel therapeutic combination in osteosarcoma

ResearchCo Investigator · Awarded by The Paula Takacs Foundation For Sarcoma Research · 2026 - 2027

Phase 1 Study of X-PACT (X-ray Psoralen Activated Cancer Therapy)

Clinical TrialPrincipal Investigator · Awarded by Immunolight, LLC · 2021 - 2027

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Education


University of Vermont, College of Medicine · 2006 M.D.