Overview
Genetic approaches to organ regeneration
Cardiac regeneration
Appendage regeneration
Developmental biology
Current Appointments & Affiliations
James B. Duke Distinguished Professor Emeritus of Regenerative Biology
·
2025 - Present
Cell Biology,
Basic Science Departments
Professor Emeritus of Cell Biology
·
2025 - Present
Cell Biology,
Basic Science Departments
Associate of the Duke Initiative for Science & Society
·
2018 - Present
Duke Science & Society,
University Initiatives & Academic Support Units
Recent Publications
Epicardial Tcf21 facilitates cardiomyocyte dedifferentiation and heart regeneration in zebrafish.
Journal Article Dev Biol · February 2026 Unlike mammals, zebrafish (Danio rerio) are able to regenerate their hearts after injury, making them an excellent model organism for studying the molecular mechanisms underlying heart regeneration. Epicardium, the outermost layer of the heart, is an essen ... Full text Link to item CiteSignal control during tissue regeneration in adult animals.
Journal Article Nat Rev Mol Cell Biol · November 11, 2025 Tissue regeneration has historically been the subject of intense scientific scrutiny, from basic biology to applications in regenerative medicine. Use of model organisms and cutting-edge technologies have uncovered various mechanisms of regeneration, but u ... Full text Link to item CiteDdx61-enriched condensates refine heart regeneration programs.
Journal Article Nat Commun · October 9, 2025 Gene regulatory mechanisms that underlie tissue regeneration have been largely studied at the level of transcription. Here, proximity labeling methods identify increased presence of the RNA helicase and P-body marker Ddx61 in adult zebrafish cardiomyocytes ... Full text Link to item CiteRecent Grants
iPediHeart: Interdisciplinary Research Training Program for Pediatric Heart Disease
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2025 - 2030Advanced Immunobiology Traning Program for Surgeons
Inst. Training Prgm or CMEMentor · Awarded by National Institute of Allergy and Infectious Diseases · 2019 - 2029Mechanism of epidermal coordination during development and regeneration in zebrafish
ResearchCo-Mentor · Awarded by National Institute of Arthritis and Musculoskeletal and Skin Diseases · 2023 - 2028View All Grants
Education, Training & Certifications
Massachusetts Institute of Technology ·
1998
Ph.D.