Overview
Genetic approaches to organ regeneration
Cardiac regeneration
Appendage regeneration
Developmental biology
Current Appointments & Affiliations
James B. Duke Distinguished Professor Emeritus of Regenerative Biology
·
2025 - Present
Cell Biology,
Basic Science Departments
Professor Emeritus of Cell Biology
·
2025 - Present
Cell Biology,
Basic Science Departments
Director of the Duke Regeneration Center
·
2021 - Present
Duke Regeneration Center,
Basic Science Departments
Member of the Duke Cancer Institute
·
2003 - Present
Duke Cancer Institute,
Institutes and Centers
Associate of the Duke Initiative for Science & Society
·
2018 - Present
Duke Science & Society,
University Initiatives & Academic Support Units
Recent Publications
In toto live imaging of Erk signaling dynamics in developing zebrafish hepatocytes.
Journal Article Dev Biol · July 2025 Regional and tissue-wide regulation of signaling pathways orchestrates cellular proliferation and differentiation during organ development. In this study, we established an imaging platform for longitudinal analysis of liver development in live developing ... Full text Link to item CitePhased ERK responsiveness and developmental robustness regulate teleost skin morphogenesis.
Journal Article Proc Natl Acad Sci U S A · March 11, 2025 Elongation of the vertebrate embryonic axis necessitates rapid expansion of the epidermis to accommodate the growth of underlying tissues. Here, we generated a toolkit to visualize and quantify signaling in entire cell populations of the periderm, the oute ... Full text Link to item CiteHallmarks of regeneration.
Journal Article Cell Stem Cell · September 5, 2024 Regeneration is a heroic biological process that restores tissue architecture and function in the face of day-to-day cell loss or the aftershock of injury. Capacities and mechanisms for regeneration can vary widely among species, organs, and injury context ... Full text Link to item CiteRecent Grants
Advanced Immunobiology Traning Program for Surgeons
Inst. Training Prgm or CMEMentor · Awarded by National Institute of Allergy and Infectious Diseases · 2019 - 2029Mechanism of epidermal coordination during development and regeneration in zebrafish
ResearchCo-Mentor · Awarded by National Institute of Arthritis and Musculoskeletal and Skin Diseases · 2023 - 2028Dissecting the Dynamics of Tissue Patterning During Regeneration
FellowshipCo-Sponsor · Awarded by Jane Coffin Childs Memorial Fund for Medical Research · 2023 - 2026View All Grants
Education, Training & Certifications
Massachusetts Institute of Technology ·
1998
Ph.D.