Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Postdoctoral Fellow, Cardiology, Children's Hospital 2000 - 2003
  • Research Fellow, University of Utah 1998 - 2000
  • Ph.D., Massachusetts Institute of Technology 1998
• 

  Duke Appointment History

  • Acting Chair of Cell Biology, Cell Biology, Basic Science Departments 2015
  • Associate Professor of Cell Biology, Cell Biology, Basic Science Departments 2009 - 2012
  • Assistant Professor of Cell Biology, Cell Biology, Basic Science Departments 2003 - 2009
• Recognition
• 

  In the News

  • NOV 3, 2016

    Scientists Find Key Protein For Spinal Cord Repair

  • APR 8, 2016

    Daily Mail

    Study reveals hidden DNA that could be 'reawakened'

  • APR 7, 2016

    Gizmag

    DNA sequence behind muscle regeneration begins to unravel

  • APR 6, 2016

    Duke Study Uncovers Genetic Elements That Drive Regeneration

  • MAR 22, 2016

    Nature

    Transgenic zebrafish forms technicolor 'skinbow'

  • MAR 21, 2016

    Technicolor Zebrafish Reveal How Skin Heals

  • MAY 1, 2015

    Duke Study Uncovers Foundations of Heart Regeneration
• 

  Awards & Honors

  • Distinguished Achievement Award. Carleton College. 2017
  • Merit Award. American Heart Association. 2016
  • Ruth and A. Morris Williams Prize in Basic Research. Duke University School of Medicine. 2011
  • Early Career Scientist. Howard Hughes Medical Institute. 2009
  • Pew Scholars in the Biomedical Sciences. Pew Charitable Trusts, The. 2006
• Research
• 

  Selected Grants

  • Medical Scientist Training Program awarded by National Institutes of Health 1997 - 2022
  • Regulation of Myocardial Regeneration in Zebrafish awarded by National Institutes of Health 2005 - 2022
  • Training Program in Developmental and Stem Cell Biology awarded by National Institutes of Health 2001 - 2022
  • Multidisciplinary Heart and Vascular Diseases awarded by National Institutes of Health 1975 - 2021
  • Polyploidy in Cardiac Development and Tissue Repair in Drosophila awarded by National Institutes of Health 2018 - 2020
  • Eliciting heart regeneration through cardiomyocyte division awarded by Fondation Leducq 2016 - 2020
  • Identification and application of regulatory elements for heart regeneration awarded by National Institutes of Health 2016 - 2020
  • Pronobis - 2017: Bioactive peptides as modulators of tissue regeneration awarded by Life Sciences Research Foundation 2017 - 2020
  • Identifying a transcription factor collective that specifies cardiomyocyte regeneration awarded by  American Heart Association 2017 - 2020
  • Genetics Training Grant awarded by National Institutes of Health 1979 - 2020
  • Organization and Function of Cellular Structure awarded by National Institutes of Health 1975 - 2020
  • Mechanisms protecting cell surface integrity in giant vacuolated cells of the notochord awarded by National Institutes of Health 2017 - 2020
  • Interdisciplinary Training Program in Lung Disease awarded by National Institutes of Health 2009 - 2020
  • Modulation of heart regeneration by enhancer-delivered factors awarded by  American Heart Association 2018 - 2019
  • Regulation of the Epicardial Injury Response During Heart Regeneration in Zebrafish awarded by National Institutes of Health 2016 - 2019
  • Regulatory Mechanisms of Zebrafish Heart Regeneration awarded by  American Heart Association 2017 - 2019
  • Regulation of glial bridging during spinal cord regeneration in zebrafish awarded by National Institutes of Health 2016 - 2018
  • Duke Research Training Program for Pediatricians awarded by National Institutes of Health 2002 - 2018
  • Biomarkers of Heart Regeneration awarded by National Institutes of Health 2013 - 2018
  • Dissecting the directional regeneration of ventricular epicardium awarded by  American Heart Association 2015 - 2018
  • Regulation of Appendage Regeneration in Zebrafish awarded by National Institutes of Health 2006 - 2018
  • Serial Block Face Scanning Electron Microscope awarded by National Institutes of Health 2016 - 2018
  • Center for Molecular & Cellular Studies of Ped Disease awarded by National Institutes of Health 2003 - 2018
  • Regulation of cardiomyocyte proliferation dynamics during zebrafish heart development awarded by March of Dimes 2014 - 2017
  • Lightsheet Imaging System awarded by National Institutes of Health 2016 - 2017
  • Role of Developmental Signaling Pathways in Tuberculosis Pathogenesis awarded by National Institutes of Health 2017
  • CHROMATIN REGULATORY EVENTS UNDERLYING ZEBRAFISH HEART REGENERATION awarded by National Institutes of Health 2014 - 2017
  • Vegf Signaling and Cardiac Chamber Morphogenesis in Zebrafish awarded by National Institutes of Health 2015 - 2016
  • Regeneration Next Initiative Annual Retreat awarded by North Carolina Biotechnology Center 2016
  • Dissecting the directional regeneration of ventricular epicardium awarded by  American Heart Association 2015 - 2016
  • Mechanisms of Neuregulin 1 in Heart Regeneration awarded by National Institutes of Health 2015 - 2016
  • 2016 Weinstein Cardiovascular Development and Regeneration Conference awarded by March of Dimes 2016
  • 2016 Weinstein Cardiovascular Development and Regeneration Conference Organizing Committee awarded by The Company of Biologists 2015 - 2016
  • Visualizing and dissecting epicardial regeneration in zebrafish awarded by  American Heart Association 2014 - 2016
  • Multidisciplinary Neonatal Training Grant awarded by National Institutes of Health 2010 - 2015
  • Identifying mechanisms of heart regeneration awarded by National Institutes of Health 2011 - 2014
• Publications & Artistic Works
• 

  Selected Publications

  • Book Sections

    • Major, RJ, and Poss, KD. "III. Does heart regeneration occur?: B. Zebrafish heart regeneration." In Heart Regeneration: Stem Cells and Beyond, 59-80. January 1, 2012.  Full Text

  • Conference Papers

    • Merriman, AF, Chen, C, and Poss, KD. "Identification of new regeneration mutants in zebrafish by a forward genetic screen." 2015.  Link to Item
    • Waxman, JS, Keegan, BR, Roberts, RW, Poss, KD, and Yelon, D. "Hoxb5b acts downstream of retinoic acid signaling in the forelimb field to restrict heart field potential in zebrafish." July 15, 2008.  Full Text  Link to Item
    • Kikuchi, K, and Poss, KD. "Cardiac progenitors during zebrafish heart regeneration." August 31, 2007.  Link to Item
    • Lee, Y, Grill, S, Murphy-Ryan, M, and Poss, KD. "A proximodistal gradient of Fgf signaling defines position-dependent rates of zebrafish fin regeneration." July 15, 2005.  Link to Item

  • Journal Articles

    • Wopat, S, Bagwell, J, Sumigray, KD, Dickson, AL, Huitema, LFA, Poss, KD, Schulte-Merker, S, and Bagnat, M. "Spine Patterning Is Guided by Segmentation of the Notochord Sheath." Cell reports 22, no. 8 (February 2018): 2026-2038.  Full Text
    • Yang, XH, Nadadur, RD, Hilvering, CR, Bianchi, V, Werner, M, Mazurek, SR, Gadek, M, Shen, KM, Goldman, JA, Tyan, L, Bekeny, J, Hall, JM, Lee, N, Perez-Cervantes, C, Burnicka-Turek, O, Poss, KD, Weber, CR, de Laat, W, Ruthenburg, AJ, and Moskowitz, IP. "Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm." eLife 6 (December 27, 2017).  Full Text
    • Chen, C-H, and Poss, KD. "Regeneration Genetics." Annual review of genetics 51 (November 2017): 63-82.  Full Text
    • Cao, J, Wang, J, Jackman, CP, Cox, AH, Trembley, MA, Balowski, JJ, Cox, BD, De Simone, A, Dickson, AL, Di Talia, S, Small, EM, Kiehart, DP, Bursac, N, and Poss, KD. "Tension Creates an Endoreplication Wavefront that Leads Regeneration of Epicardial Tissue." Developmental cell 42, no. 6 (September 2017): 600-615.e4.  Full Text
    • Tornini, VA, Thompson, JD, Allen, RL, and Poss, KD. "Live fate-mapping of joint-associated fibroblasts visualizes expansion of cell contributions during zebrafish fin regeneration." Development (Cambridge, England) 144, no. 16 (August 2017): 2889-2895.  Full Text
    • Tzahor, E, and Poss, KD. "Cardiac regeneration strategies: Staying young at heart." Science (New York, N.Y.) 356, no. 6342 (June 8, 2017): 1035-1039. (Review)  Full Text
    • Goldman, JA, Kuzu, G, Lee, N, Karasik, J, Gemberling, M, Foglia, MJ, Karra, R, Dickson, AL, Sun, F, Tolstorukov, MY, and Poss, KD. "Resolving Heart Regeneration by Replacement Histone Profiling." Developmental cell 40, no. 4 (February 2017): 392-404.e5.  Full Text
    • Karra, R, and Poss, KD. "Redirecting cardiac growth mechanisms for therapeutic regeneration." The Journal of clinical investigation 127, no. 2 (February 2017): 427-436. (Review)  Full Text
    • Nichols, JT, Blanco-Sánchez, B, Brooks, EP, Parthasarathy, R, Dowd, J, Subramanian, A, Nachtrab, G, Poss, KD, Schilling, TF, and Kimmel, CB. "Ligament versus bone cell identity in the zebrafish hyoid skeleton is regulated by mef2ca." Development (Cambridge, England) 143, no. 23 (December 2016): 4430-4440.  Full Text
    • Tornini, VA, Puliafito, A, Slota, LA, Thompson, JD, Nachtrab, G, Kaushik, A-L, Kapsimali, M, Primo, L, Di Talia, S, and Poss, KD. "Live Monitoring of Blastemal Cell Contributions during Appendage Regeneration." Current biology : CB 26, no. 22 (November 3, 2016): 2981-2991.  Full Text
    • Mokalled, MH, Patra, C, Dickson, AL, Endo, T, Stainier, DYR, and Poss, KD. "Injury-induced ctgfa directs glial bridging and spinal cord regeneration in zebrafish." Science (New York, N.Y.) 354, no. 6312 (November 2016): 630-634.  Full Text
    • Di Talia, S, and Poss, KD. "Monitoring Tissue Regeneration at Single-Cell Resolution." Cell stem cell 19, no. 4 (October 2016): 428-431.  Full Text
    • Cao, J, and Poss, KD. "Explant culture of adult zebrafish hearts for epicardial regeneration studies." Nature protocols 11, no. 5 (May 2016): 872-881.  Full Text
    • Foglia, MJ, Cao, J, Tornini, VA, and Poss, KD. "Multicolor mapping of the cardiomyocyte proliferation dynamics that construct the atrium." Development (Cambridge, England) 143, no. 10 (May 2016): 1688-1696.  Full Text
    • Han, Y, and Poss, KD. "Accessories to Limb Regeneration." Developmental cell 37, no. 4 (May 2016): 297-298.  Full Text
    • Kang, J, Hu, J, Karra, R, Dickson, AL, Tornini, VA, Nachtrab, G, Gemberling, M, Goldman, JA, Black, BL, and Poss, KD. "Modulation of tissue repair by regeneration enhancer elements." Nature 532, no. 7598 (April 6, 2016): 201-206.  Full Text
    • Chen, C-H, Puliafito, A, Cox, BD, Primo, L, Fang, Y, Di Talia, S, and Poss, KD. "Multicolor Cell Barcoding Technology for Long-Term Surveillance of Epithelial Regeneration in Zebrafish." Developmental cell 36, no. 6 (March 2016): 668-680.  Full Text
    • Foglia, MJ, and Poss, KD. "Building and re-building the heart by cardiomyocyte proliferation." Development (Cambridge, England) 143, no. 5 (March 2016): 729-740. (Review)  Full Text
    • Cao, J, Navis, A, Cox, BD, Dickson, AL, Gemberling, M, Karra, R, Bagnat, M, and Poss, KD. "Single epicardial cell transcriptome sequencing identifies Caveolin 1 as an essential factor in zebrafish heart regeneration." Development (Cambridge, England) 143, no. 2 (January 2016): 232-243.  Full Text
    • Wang, J, and Poss, KD. "Methodologies for Inducing Cardiac Injury and Assaying Regeneration in Adult Zebrafish." Methods in molecular biology (Clifton, N.J.) 1451 (January 2016): 225-235.  Full Text
    • Karra, R, Knecht, AK, Kikuchi, K, and Poss, KD. "Myocardial NF-κB activation is essential for zebrafish heart regeneration." Proceedings of the National Academy of Sciences of the United States of America 112, no. 43 (October 15, 2015): 13255-13260.  Full Text
    • Chen, C-H, Merriman, AF, Savage, J, Willer, J, Wahlig, T, Katsanis, N, Yin, VP, and Poss, KD. "Transient laminin beta 1a Induction Defines the Wound Epidermis during Zebrafish Fin Regeneration." PLoS genetics 11, no. 8 (August 25, 2015): e1005437-.  Full Text
    • Mahmoud, AI, O'Meara, CC, Gemberling, M, Zhao, L, Bryant, DM, Zheng, R, Gannon, JB, Cai, L, Choi, W-Y, Egnaczyk, GF, Burns, CE, Burns, CG, MacRae, CA, Poss, KD, and Lee, RT. "Nerves Regulate Cardiomyocyte Proliferation and Heart Regeneration." Developmental cell 34, no. 4 (August 5, 2015): 387-399.  Full Text
    • Nagelberg, D, Wang, J, Su, R, Torres-Vázquez, J, Targoff, KL, Poss, KD, and Knaut, H. "Origin, Specification, and Plasticity of the Great Vessels of the Heart." Current biology : CB 25, no. 16 (August 5, 2015): 2099-2110.  Full Text
    • Palencia-Desai, S, Rost, MS, Schumacher, JA, Ton, QV, Craig, MP, Baltrunaite, K, Koenig, AL, Wang, J, Poss, KD, Chi, NC, Stainier, DYR, and Sumanas, S. "Myocardium and BMP signaling are required for endocardial differentiation." Development (Cambridge, England) 142, no. 13 (July 2015): 2304-2315.  Full Text
    • Kang, J, Karra, R, and Poss, KD. "Back in Black." Developmental cell 33, no. 6 (June 2015): 623-624.  Full Text
    • Wang, J, Cao, J, Dickson, AL, and Poss, KD. "Epicardial regeneration is guided by cardiac outflow tract and Hedgehog signalling." Nature 522, no. 7555 (June 2015): 226-230.  Full Text
    • Gemberling, M, Karra, R, Dickson, AL, and Poss, KD. "Nrg1 is an injury-induced cardiomyocyte mitogen for the endogenous heart regeneration program in zebrafish." eLife 4 (April 2015).  Full Text  Open Access Copy
    • Schindler, YL, Garske, KM, Wang, J, Firulli, BA, Firulli, AB, Poss, KD, and Yelon, D. "Hand2 elevates cardiomyocyte production during zebrafish heart development and regeneration." Development (Cambridge, England) 141, no. 16 (August 2014): 3112-3122.  Full Text
    • Tornini, VA, and Poss, KD. "Keeping at arm's length during regeneration." Developmental cell 29, no. 2 (April 2014): 139-145. (Review)  Full Text
    • Chen, CH, Durand, E, Wang, J, Zon, LI, and Poss, KD. "Zebraflash transgenic lines for in vivo bioluminescence imaging of stem cells and regeneration in adult zebrafish." Development (Cambridge) 140, no. 24 (December 15, 2013): 4988-4997.  Full Text
    • Gemberling, M, Bailey, TJ, Hyde, DR, and Poss, KD. "The zebrafish as a model for complex tissue regeneration." Trends in Genetics 29, no. 11 (November 1, 2013): 611-620. (Review)  Full Text
    • Gemberling, M, Bailey, TJ, Hyde, DR, and Poss, KD. "The zebrafish as a model for complex tissue regeneration." Trends Genet 29, no. 11 (November 2013): 611-620. (Review)  Full Text  Link to Item
    • Wang, J, Karra, R, Dickson, AL, and Poss, KD. "Fibronectin is deposited by injury-activated epicardial cells and is necessary for zebrafish heart regeneration." Dev Biol 382, no. 2 (October 15, 2013): 427-435.  Full Text  Link to Item
    • Kang, J, Nachtrab, G, and Poss, KD. "Local Dkk1 crosstalk from breeding ornaments impedes regeneration of injured male zebrafish fins." Dev Cell 27, no. 1 (October 14, 2013): 19-31.  Full Text  Link to Item
    • Johnson, AN, Mokalled, MH, Valera, JM, Poss, KD, and Olson, EN. "Post-transcriptional regulation of myotube elongation and myogenesis by Hoi Polloi." DEVELOPMENT 140, no. 17 (September 1, 2013): 3645-3656.  Full Text  Link to Item
    • Nachtrab, G, Kikuchi, K, Tornini, VA, and Poss, KD. "Transcriptional components of anteroposterior positional information during zebrafish fin regeneration." Development 140, no. 18 (September 2013): 3754-3764.  Full Text  Link to Item
    • Fang, Y, Gupta, V, Karra, R, Holdway, JE, Kikuchi, K, and Poss, KD. "Translational profiling of cardiomyocytes identifies an early Jak1/Stat3 injury response required for zebrafish heart regeneration." Proc Natl Acad Sci U S A 110, no. 33 (August 13, 2013): 13416-13421.  Full Text  Link to Item
    • Gupta, V, Gemberling, M, Karra, R, Rosenfeld, GE, Evans, T, and Poss, KD. "An injury-responsive gata4 program shapes the zebrafish cardiac ventricle." Curr Biol 23, no. 13 (July 8, 2013): 1221-1227.  Full Text  Link to Item
    • Guner-Ataman, B, Paffett-Lugassy, N, Adams, MS, Nevis, KR, Jahangiri, L, Obregon, P, Kikuchi, K, Poss, KD, Burns, CE, and Burns, CG. "Zebrafish second heart field development relies on progenitor specification in anterior lateral plate mesoderm and nkx2.5 function." DEVELOPMENT 140, no. 6 (March 2013): 1353-1363.  Full Text  Link to Item
    • Choi, W-Y, Gemberling, M, Wang, J, Holdway, JE, Shen, M-C, Karlstrom, RO, and Poss, KD. "In vivo monitoring of cardiomyocyte proliferation to identify chemical modifiers of heart regeneration." Development 140, no. 3 (February 1, 2013): 660-666.  Full Text  Link to Item
    • Gupta, V, Gemberling, M, Karra, R, Rosenfeld, GE, Evans, T, and Poss, KD. "An injury-responsive gata4 program shapes the zebrafish cardiac ventricle." Current Biology 23, no. 13 (2013): 1221-1227.  Full Text
    • Nachtrab, G, and Poss, KD. "Toward a blueprint for regeneration." Development 139, no. 15 (August 2012): 2639-2642.  Full Text  Link to Item
    • Yin, VP, Lepilina, A, Smith, A, and Poss, KD. "Regulation of zebrafish heart regeneration by miR-133." Dev Biol 365, no. 2 (May 15, 2012): 319-327.  Full Text  Link to Item
    • Gupta, V, and Poss, KD. "Clonally dominant cardiomyocytes direct heart morphogenesis. (Published online)" Nature 484, no. 7395 (April 25, 2012): 479-484.  Full Text  Link to Item
    • Singh, SP, Holdway, JE, and Poss, KD. "Regeneration of amputated zebrafish fin rays from de novo osteoblasts." Dev Cell 22, no. 4 (April 17, 2012): 879-886.  Full Text  Link to Item
    • Choi, W-Y, and Poss, KD. "Cardiac regeneration." Curr Top Dev Biol 100 (2012): 319-344. (Review)  Full Text  Link to Item
    • Kikuchi, K, and Poss, KD. "Cardiac regenerative capacity and mechanisms." Annual Review of Cell and Developmental Biology 28 (2012): 719-741.  Full Text
    • Le, X, Pugach, EK, Hettmer, S, Storer, NY, Liu, J, Wills, AA, DiBiase, A, Chen, EY, Ignatius, MS, Poss, KD, Wagers, AJ, Langenau, DM, and Zon, LI. "A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development." Development (Cambridge) 140, no. 11 (2012): 2354-2364.  Full Text
    • Nachtrab, G, Czerwinski, M, and Poss, KD. "Sexually dimorphic fin regeneration in zebrafish controlled by androgen/GSK3 signaling." Curr Biol 21, no. 22 (November 22, 2011): 1912-1917.  Full Text  Link to Item
    • Wang, J, Panáková, D, Kikuchi, K, Holdway, JE, Gemberling, M, Burris, JS, Singh, SP, Dickson, AL, Lin, Y-F, Sabeh, MK, Werdich, AA, Yelon, D, Macrae, CA, and Poss, KD. "The regenerative capacity of zebrafish reverses cardiac failure caused by genetic cardiomyocyte depletion." Development 138, no. 16 (August 2011): 3421-3430.  Full Text  Link to Item
    • Kikuchi, K, Gupta, V, Wang, J, Holdway, JE, Wills, AA, Fang, Y, and Poss, KD. "tcf21+ epicardial cells adopt non-myocardial fates during zebrafish heart development and regeneration." Development 138, no. 14 (July 2011): 2895-2902.  Full Text  Link to Item
    • Shin, D, Lee, Y, Poss, KD, and Stainier, DYR. "Restriction of hepatic competence by Fgf signaling." Development 138, no. 7 (April 2011): 1339-1348.  Full Text  Link to Item
    • Kikuchi, K, Holdway, JE, Major, RJ, Blum, N, Dahn, RD, Begemann, G, and Poss, KD. "Retinoic acid production by endocardium and epicardium is an injury response essential for zebrafish heart regeneration." Dev Cell 20, no. 3 (March 15, 2011): 397-404.  Link to Item
    • Qin, Z, Kidd, AR, Thomas, JL, Poss, KD, Hyde, DR, Raymond, PA, and Thummel, R. "FGF signaling regulates rod photoreceptor cell maintenance and regeneration in zebrafish." Experimental Eye Research 93, no. 5 (2011): 726-734.  Full Text
    • Liu, J, Bressan, M, Hassel, D, Huisken, J, Staudt, D, Kikuchi, K, Poss, KD, Mikawa, T, and Stainier, DYR. "A dual role for ErbB2 signaling in cardiac trabeculation." Development 137, no. 22 (November 2010): 3867-3875.  Full Text  Open Access Copy  Link to Item
    • Poss, KD. "Advances in understanding tissue regenerative capacity and mechanisms in animals." Nat Rev Genet 11, no. 10 (October 2010): 710-722. (Review)  Full Text  Link to Item
    • Lee, Y, Nachtrab, G, Klinsawat, PW, Hami, D, and Poss, KD. "Ras controls melanocyte expansion during zebrafish fin stripe regeneration." Dis Model Mech 3, no. 7-8 (July 2010): 496-503.  Full Text  Open Access Copy  Link to Item
    • Yin, C, Kikuchi, K, Hochgreb, T, Poss, KD, and Stainier, DYR. "Hand2 regulates extracellular matrix remodeling essential for gut-looping morphogenesis in zebrafish." Dev Cell 18, no. 6 (June 15, 2010): 973-984.  Full Text  Link to Item
    • Kikuchi, K, Holdway, JE, Werdich, AA, Anderson, RM, Fang, Y, Egnaczyk, GF, Evans, T, Macrae, CA, Stainier, DYR, and Poss, KD. "Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes." Nature 464, no. 7288 (March 25, 2010): 601-605.  Full Text  Link to Item
    • Gonzalez-Quevedo, R, Lee, Y, Poss, KD, and Wilkinson, DG. "Neuronal regulation of the spatial patterning of neurogenesis." Dev Cell 18, no. 1 (January 19, 2010): 136-147.  Full Text  Link to Item
    • Poss, K. "Cardiac Regeneration in the Zebrafish Model System." Heart Development and Regeneration (2010): 839-853.  Full Text
    • Gonzalez-Quevedo, R, Sobieszczuk, DF, Poliakov, A, Lee, Y, Poss, KD, and Wilkinson, DG. "Feedback regulation of neurogenesis." DEVELOPMENTAL BIOLOGY 331, no. 2 (July 15, 2009): 388-389.  Full Text  Link to Item
    • Lee, Y, Hami, D, De Val, S, Kagermeier-Schenk, B, Wills, AA, Black, BL, Weidinger, G, and Poss, KD. "Maintenance of blastemal proliferation by functionally diverse epidermis in regenerating zebrafish fins." Dev Biol 331, no. 2 (July 15, 2009): 270-280.  Full Text  Link to Item
    • Nachtrab, G, and Poss, KD. "Genetic DISC-section of regeneration in Drosophila." Dev Cell 16, no. 6 (June 2009): 777-778.  Full Text  Link to Item
    • Waxman, JS, Keegan, BR, Roberts, RW, Poss, KD, and Yelon, D. "Hoxb5b acts downstream of retinoic acid signaling in the forelimb field to restrict heart field potential in zebrafish." Dev Cell 15, no. 6 (December 2008): 923-934.  Full Text  Link to Item
    • Marques, SR, Lee, Y, Poss, KD, and Yelon, D. "Reiterative roles for FGF signaling in the establishment of size and proportion of the zebrafish heart." Dev Biol 321, no. 2 (September 15, 2008): 397-406.  Full Text  Link to Item
    • Wills, AA, Kidd, AR, Lepilina, A, and Poss, KD. "Fgfs control homeostatic regeneration in adult zebrafish fins." Development 135, no. 18 (September 2008): 3063-3070.  Full Text  Link to Item
    • Yin, VP, and Poss, KD. "New regulators of vertebrate appendage regeneration." Curr Opin Genet Dev 18, no. 4 (August 2008): 381-386. (Review)  Full Text  Link to Item
    • Yin, VP, Thomson, JM, Thummel, R, Hyde, DR, Hammond, SM, and Poss, KD. "Fgf-dependent depletion of microRNA-133 promotes appendage regeneration in zebrafish." Genes Dev 22, no. 6 (March 15, 2008): 728-733.  Full Text  Link to Item
    • Wills, AA, Holdway, JE, Major, RJ, and Poss, KD. "Regulated addition of new myocardial and epicardial cells fosters homeostatic cardiac growth and maintenance in adult zebrafish." Development 135, no. 1 (January 2008): 183-192.  Full Text  Link to Item
    • Shin, D, Shin, CH, Tucker, J, Ober, EA, Rentzsch, F, Poss, KD, Hammerschmidt, M, Mullins, MC, and Stainier, DYR. "Bmp and Fgf signaling are essential for liver specification in zebrafish." Development 134, no. 11 (June 2007): 2041-2050.  Full Text  Link to Item
    • Nechiporuk, A, Linbo, T, Poss, KD, and Raible, DW. "Specification of epibranchial placodes in zebrafish." Development 134, no. 3 (February 2007): 611-623.  Full Text  Link to Item
    • Poss, KD. "Getting to the heart of regeneration in zebrafish." Semin Cell Dev Biol 18, no. 1 (February 2007): 36-45. (Review)  Full Text  Link to Item
    • Major, RJ, and Poss, KD. "Zebrafish Heart Regeneration as a Model for Cardiac Tissue Repair." Drug Discov Today Dis Models 4, no. 4 (2007): 219-225.  Full Text  Link to Item
    • Lepilina, A, Coon, AN, Kikuchi, K, Holdway, JE, Roberts, RW, Burns, CG, and Poss, KD. "A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration." Cell 127, no. 3 (November 3, 2006): 607-619.  Full Text  Link to Item
    • Lee, Y, Grill, S, Sanchez, A, Murphy-Ryan, M, and Poss, KD. "Fgf signaling instructs position-dependent growth rate during zebrafish fin regeneration." Development 132, no. 23 (December 2005): 5173-5183.  Full Text  Link to Item
    • Poss, KD. "A zebrafish model of germ cell aneuploidy." Cell Cycle 3, no. 10 (October 2004): 1225-1226.  Full Text  Link to Item
    • Poss, KD, Nechiporuk, A, Stringer, KF, Lee, C, and Keating, MT. "Germ cell aneuploidy in zebrafish with mutations in the mitotic checkpoint gene mps1." Genes Dev 18, no. 13 (July 1, 2004): 1527-1532.  Full Text  Link to Item
    • Traver, D, Paw, BH, Poss, KD, Penberthy, WT, Lin, S, and Zon, LI. "Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants." Nat Immunol 4, no. 12 (December 2003): 1238-1246.  Full Text  Link to Item
    • Nechiporuk, A, Poss, KD, Johnson, SL, and Keating, MT. "Positional cloning of a temperature-sensitive mutant emmental reveals a role for sly1 during cell proliferation in zebrafish fin regeneration." Dev Biol 258, no. 2 (June 15, 2003): 291-306.  Link to Item
    • Poss, KD, Keating, MT, and Nechiporuk, A. "Tales of regeneration in zebrafish." Dev Dyn 226, no. 2 (February 2003): 202-210. (Review)  Full Text  Link to Item
    • Gillette-Ferguson, I, Ferguson, DG, Poss, KD, and Moorman, SJ. "Changes in gravitational force induce alterations in gene expression that can be monitored in the live, developing zebrafish heart." Adv Space Res 32, no. 8 (2003): 1641-1646.  Link to Item
    • Poss, KD, Wilson, LG, and Keating, MT. "Heart regeneration in zebrafish." Science 298, no. 5601 (December 13, 2002): 2188-2190.  Full Text  Link to Item
    • Poss, KD, Nechiporuk, A, Hillam, AM, Johnson, SL, and Keating, MT. "Mps1 defines a proximal blastemal proliferative compartment essential for zebrafish fin regeneration." Development 129, no. 22 (November 2002): 5141-5149.  Link to Item
    • Poss, KD, Shen, J, and Keating, MT. "Induction of lef1 during zebrafish fin regeneration." Developmental Dynamics 219, no. 2 (October 24, 2000): 282-286.  Full Text
    • Poss, KD, Shen, J, and Keating, MT. "Induction of lef1 during zebrafish fin regeneration." Dev Dyn 219, no. 2 (October 2000): 282-286.  Full Text  Link to Item
    • Poss, KD, Shen, J, Nechiporuk, A, McMahon, G, Thisse, B, Thisse, C, and Keating, MT. "Roles for Fgf signaling during zebrafish fin regeneration." Dev Biol 222, no. 2 (June 15, 2000): 347-358.  Full Text  Link to Item
    • Nath, KA, Haggard, JJ, Croatt, AJ, Grande, JP, Poss, KD, and Alam, J. "The indispensability of heme oxygenase-1 in protecting against acute heme protein-induced toxicity in vivo." Am J Pathol 156, no. 5 (May 2000): 1527-1535.  Full Text  Link to Item
    • Shiraishi, F, Curtis, LM, Truong, L, Poss, K, Visner, GA, Madsen, K, Nick, HS, and Agarwal, A. "Heme oxygenase-1 gene ablation or expression modulates cisplatin-induced renal tubular apoptosis." American Journal of Physiology - Renal Physiology 278, no. 5 47-5 (2000): F726-F736.
    • Ferris, CD, Jaffrey, SR, Sawa, A, Takahashi, M, Brady, SD, Barrow, RK, Tysoe, SA, Wolosker, H, Barañano, DE, Doré, S, Poss, KD, and Snyder, SH. "Haem oxygenase-1 prevents cell death by regulating cellular iron." Nat Cell Biol 1, no. 3 (July 1999): 152-157.  Full Text  Link to Item
    • Demas, GE, Kriegsfeld, LJ, Poss, KD, Tonegawa, S, and Nelson, RJ. "Circadian locomotor rhythms in mice with targeted disruption of the gene for the carbon monoxide synthesizing enzyme, heme oxygenase-2." Biological Rhythm Research 30, no. 3 (1999): 282-289.  Full Text
    • Soares, MP, Lin, Y, Anrather, J, Csizmadia, E, Takigami, K, Sato, K, Grey, ST, Colvin, RB, Choi, AM, Poss, KD, and Bach, FH. "Expression of heme oxygenase-1 can determine cardiac xenograft survival." Nat Med 4, no. 9 (September 1998): 1073-1077.  Full Text  Link to Item
    • Dennery, PA, Spitz, DR, Yang, G, Tatarov, A, Lee, CS, Shegog, ML, and Poss, KD. "Oxygen toxicity and iron accumulation in the lungs of mice lacking heme oxygenase-2." J Clin Invest 101, no. 5 (March 1, 1998): 1001-1011.  Full Text  Link to Item
    • Burnett, AL, Johns, DG, Kriegsfeld, LJ, Klein, SL, Calvin, DC, Demas, GE, Schramm, LP, Tonegawa, S, Nelson, RJ, Snyder, SH, and Poss, KD. "Ejaculatory abnormalities in mice with targeted disruption of the gene for heme oxygenase-2." Nat Med 4, no. 1 (January 1998): 84-87.  Link to Item
    • Zakhary, R, Poss, KD, Jaffrey, SR, Ferris, CD, Tonegawa, S, and Snyder, SH. "Targeted gene deletion of heme oxygenase 2 reveals neural role for carbon monoxide." Proc Natl Acad Sci U S A 94, no. 26 (December 23, 1997): 14848-14853.  Link to Item
    • Poss, KD, and Tonegawa, S. "Heme oxygenase 1 is required for mammalian iron reutilization." Proc Natl Acad Sci U S A 94, no. 20 (September 30, 1997): 10919-10924.  Link to Item
    • Poss, KD, and Tonegawa, S. "Reduced stress defense in heme oxygenase 1-deficient cells." Proc Natl Acad Sci U S A 94, no. 20 (September 30, 1997): 10925-10930.  Link to Item
    • Poss, KD, Thomas, MJ, Ebralidze, AK, O'Dell, TJ, and Tonegawa, S. "Hippocampal long-term potentiation is normal in heme oxygenase-2 mutant mice." Neuron 15, no. 4 (October 1995): 867-873.  Link to Item
• Teaching & Mentoring
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  Recent Courses

  • CELLBIO 493: Research Independent Study 2018
  • CMB 710C: Cell & Molecular Biology Module III 2018
  • CELLBIO 730: Stem Cell Course 2016
  • MOLCAN 730: Stem Cell Course 2016
  • PHARM 730: Stem Cell Course 2016

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