Overview
Genetic approaches to organ regeneration
Cardiac regeneration
Appendage regeneration
Developmental biology
Current Appointments & Affiliations
James B. Duke Distinguished Professor Emeritus of Regenerative Biology
·
2025 - Present
Cell Biology,
Basic Science Departments
Professor Emeritus of Cell Biology
·
2025 - Present
Cell Biology,
Basic Science Departments
Associate of the Duke Initiative for Science & Society
·
2018 - Present
Duke Science & Society,
University Initiatives & Academic Support Units
Recent Publications
Ddx61-enriched condensates refine heart regeneration programs.
Journal Article Nat Commun · October 9, 2025 Gene regulatory mechanisms that underlie tissue regeneration have been largely studied at the level of transcription. Here, proximity labeling methods identify increased presence of the RNA helicase and P-body marker Ddx61 in adult zebrafish cardiomyocytes ... Full text Link to item CiteIn toto live imaging of Erk signaling dynamics in developing zebrafish hepatocytes.
Journal Article Dev Biol · July 2025 Regional and tissue-wide regulation of signaling pathways orchestrates cellular proliferation and differentiation during organ development. In this study, we established an imaging platform for longitudinal analysis of liver development in live developing ... Full text Link to item CitePhased ERK responsiveness and developmental robustness regulate teleost skin morphogenesis.
Journal Article Proc Natl Acad Sci U S A · March 11, 2025 Elongation of the vertebrate embryonic axis necessitates rapid expansion of the epidermis to accommodate the growth of underlying tissues. Here, we generated a toolkit to visualize and quantify signaling in entire cell populations of the periderm, the oute ... Full text Link to item CiteRecent Grants
iPediHeart: Interdisciplinary Research Training Program for Pediatric Heart Disease
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2025 - 2030Advanced Immunobiology Traning Program for Surgeons
Inst. Training Prgm or CMEMentor · Awarded by National Institute of Allergy and Infectious Diseases · 2019 - 2029Mechanism of epidermal coordination during development and regeneration in zebrafish
ResearchCo-Mentor · Awarded by National Institute of Arthritis and Musculoskeletal and Skin Diseases · 2023 - 2028View All Grants
Education, Training & Certifications
Massachusetts Institute of Technology ·
1998
Ph.D.