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Kenneth Daniel Poss

James B. Duke Distinguished Professor Emeritus of Regenerative Biology
Cell Biology
Duke Box 3709, Durham, NC 27710
307 Research Drive, Nanaline Bldg Room 466 A, Durham, NC 27710

Overview


Modeling disease in zebrafish
Genetic approaches to organ regeneration
Cardiac regeneration
Appendage regeneration
Developmental biology

Current Appointments & Affiliations


James B. Duke Distinguished Professor Emeritus of Regenerative Biology · 2025 - Present Cell Biology, Basic Science Departments
Professor Emeritus of Cell Biology · 2025 - Present Cell Biology, Basic Science Departments
Director of the Duke Regeneration Center · 2021 - Present Duke Regeneration Center, Basic Science Departments
Professor in Medicine · 2016 - Present Medicine, Cardiology, Medicine
Member of the Duke Cancer Institute · 2003 - Present Duke Cancer Institute, Institutes and Centers
Associate of the Duke Initiative for Science & Society · 2018 - Present Duke Science & Society, University Initiatives & Academic Support Units

In the News


Published December 13, 2022
Gene Therapy for Heart Attacks in Mice Just Got More Precise
Published December 13, 2019
Salamanders Can Regrow Limbs. Why Can't I?
Published November 26, 2019
Seven From Duke Named Fellows of American Association for the Advancement of Science

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Recent Publications


In toto live imaging of Erk signaling dynamics in developing zebrafish hepatocytes.

Journal Article Dev Biol · July 2025 Regional and tissue-wide regulation of signaling pathways orchestrates cellular proliferation and differentiation during organ development. In this study, we established an imaging platform for longitudinal analysis of liver development in live developing ... Full text Link to item Cite

Phased ERK responsiveness and developmental robustness regulate teleost skin morphogenesis.

Journal Article Proc Natl Acad Sci U S A · March 11, 2025 Elongation of the vertebrate embryonic axis necessitates rapid expansion of the epidermis to accommodate the growth of underlying tissues. Here, we generated a toolkit to visualize and quantify signaling in entire cell populations of the periderm, the oute ... Full text Link to item Cite

Hallmarks of regeneration.

Journal Article Cell Stem Cell · September 5, 2024 Regeneration is a heroic biological process that restores tissue architecture and function in the face of day-to-day cell loss or the aftershock of injury. Capacities and mechanisms for regeneration can vary widely among species, organs, and injury context ... Full text Link to item Cite
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Recent Grants


Advanced Immunobiology Traning Program for Surgeons

Inst. Training Prgm or CMEMentor · Awarded by National Institute of Allergy and Infectious Diseases · 2019 - 2029

Mechanism of epidermal coordination during development and regeneration in zebrafish

ResearchCo-Mentor · Awarded by National Institute of Arthritis and Musculoskeletal and Skin Diseases · 2023 - 2028

Dissecting the Dynamics of Tissue Patterning During Regeneration

FellowshipCo-Sponsor · Awarded by Jane Coffin Childs Memorial Fund for Medical Research · 2023 - 2026

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Education, Training & Certifications


Massachusetts Institute of Technology · 1998 Ph.D.