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William Schuyler Jones

Professor of Medicine
Medicine, Cardiology
Duke Box 3330, Durham, NC 27710
2400 Pratt Street, 7037, Durham, NC 27705

Overview


I am an interventional cardiologist with a specific focus on the diagnosis and treatment of patients with cardiovascular disease. As a clinician, I see patients in the office and do coronary and peripheral vascular procedures (angiography and interventions) in the Duke Cardiac Catheterization Laboratory. I have served as the Medical Director of the cath lab at Duke since 2016. Alongside my partners in the cath lab, we collaborate with our cardiothoracic surgeons to hold Heart Team meetings each week, and we frequently are asked to address complex cardiovascular issues as a multidisciplinary team.

I also have a broad background in cardiovascular site-based research, multicenter clinical trials, clinical event classification, and observational analyses. I have helped to lead clinical trial efforts at the Duke Clinical Research Institute (DCRI) by designing and conducting studies evaluating new and existing treatments for patients with coronary artery disease and peripheral artery disease. My specific research interests include examining access to care and disparities in care for patients with peripheral artery disease and the design and conduct of pragmatic clinical trials in cardiovascular disease.

Current Duke Appointments & Affiliations


Professor of Medicine · 2024 - Present Medicine, Cardiology, Medicine
Professor in Population Health Sciences · 2024 - Present Population Health Sciences, Basic Science Departments
Member in the Duke Clinical Research Institute · 2013 - Present Duke Clinical Research Institute, Institutes and Centers

Recent Scholarly Works


Predictors of ischemic stroke and major bleeding among patients with atrial fibrillation in clinical practice.

Journal article Am Heart J · October 2026 BACKGROUND: Numerous risk scores exist to quantify the risk of ischemic stroke risk in patients with atrial fibrillation or flutter (AF/AFL). However, how these tools perform in cohorts or those already on oral anticoagulation (OAC) therapy is unclear. MET ... Full text Link to item Cite

Secondary prevention strategies for patients with lower extremity peripheral artery disease after successful peripheral vascular intervention.

Journal article Am Heart J · September 2026 BACKGROUND: Individuals with lower extremity peripheral artery disease (LE PAD) represent a subset of patients with atherosclerotic cardiovascular disease that are among the highest risk for major adverse cardiovascular and limb events. Despite this, LE PA ... Full text Link to item Cite
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Recent Grants


1/3 CTSA UM1 at Duke University

ResearchFaculty Member · Awarded by National Institutes of Health · 2025 - 2032

1/2 IMPRoving Outcomes in Vascular DisEase - Aortic Dissection (IMPROVE-AD)

ResearchCo Investigator · Awarded by National Heart, Lung, and Blood Institute · 2024 - 2030

View All Grants

Education


University of Arkansas, Little Rock · 2001 M.D.