Overview
Pediatric and adult clinical pharmacology and clinical trials.
Current Appointments & Affiliations
Kiser-Arena Distinguished Professor
·
2020 - Present
Pediatrics, Infectious Diseases,
Pediatrics
Professor of Pediatrics
·
2017 - Present
Pediatrics, Infectious Diseases,
Pediatrics
Member in the Duke Clinical Research Institute
·
2007 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Metronidazole exposure-response and safety in infants.
Journal Article Antimicrob Agents Chemother · November 5, 2025 The nitroimidazole antibiotic, metronidazole, is frequently prescribed to infants with serious intra-abdominal infections, and multiple dosing recommendations exist. We sought to evaluate the extent to which metronidazole doses and associated exposures ach ... Full text Link to item CiteErratum for Randell et al., "Opportunistic dried blood spot sampling validates and optimizes a pediatric population pharmacokinetic model of metronidazole".
Journal Article Antimicrob Agents Chemother · September 3, 2025 Full text Open Access Link to item CitePopulation Pharmacokinetics of Meropenem Across the Adult Lifespan.
Journal Article Clin Pharmacokinet · February 2025 BACKGROUND AND OBJECTIVE: We conducted an opportunistic pharmacokinetic study to evaluate the population pharmacokinetics of meropenem, an antimicrobial commonly used to treat Gram-negative infections in adults of different ages, including older adults, an ... Full text Link to item CiteRecent Grants
iPediHeart: Interdisciplinary Research Training Program for Pediatric Heart Disease
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2025 - 20302/3 CTSA K12 Program at Duke University
ResearchMentor · Awarded by National Institutes of Health · 2025 - 2030Unified Program for Therapeutics in Children
Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2025 - 2030View All Grants
Education, Training & Certifications
University of North Carolina, Chapel Hill, School of Medicine ·
2012
Ph.D.
Universidad Central de Venezuela (Venezuela) ·
2001
M.D.