Overview
Pediatric and adult clinical pharmacology and clinical trials.
Current Appointments & Affiliations
Kiser-Arena Distinguished Professor
·
2020 - Present
Pediatrics, Infectious Diseases,
Pediatrics
Professor of Pediatrics
·
2017 - Present
Pediatrics, Infectious Diseases,
Pediatrics
Member in the Duke Clinical Research Institute
·
2007 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Population Pharmacokinetics of Meropenem Across the Adult Lifespan.
Journal Article Clin Pharmacokinet · February 2025 BACKGROUND AND OBJECTIVE: We conducted an opportunistic pharmacokinetic study to evaluate the population pharmacokinetics of meropenem, an antimicrobial commonly used to treat Gram-negative infections in adults of different ages, including older adults, an ... Full text Link to item CiteA Pooled Pharmacokinetic Analysis for Piperacillin/Tazobactam Across Different Patient Populations: From Premature Infants to the Elderly.
Journal Article Clin Pharmacokinet · January 2025 BACKGROUND AND OBJECTIVES: The pharmacokinetics (PK) of piperacillin/tazobactam (PIP/TAZ) is highly variable across different patient populations and there are controversies regarding non-linear elimination as well as the fraction unbound of PIP (fUNB_PIP) ... Full text Link to item CiteEffect of an Electronic Pill Bottle on Hydroxychloroquine Adherence in Pediatric Lupus: Results of a Novel Direct-to-Family Pilot Trial.
Journal Article ACR Open Rheumatol · January 2025 OBJECTIVE: The objective of this study was to evaluate the preliminary effectiveness of an electronic pill bottle with automated reminders on hydroxychloroquine (HCQ) adherence in children with pediatric systemic lupus erythematosus (pSLE). METHODS: This w ... Full text Link to item CiteRecent Grants
Short-course ampicillin in preterm neonates to promote antimicrobial stewardship
ResearchCo-Mentor · Awarded by National Institutes of Health · 2025 - 2029DCRI D-COHRe Partnership for Innovation, Improved Access, and Operational Capability for Decentralized Clinical Trials of Medical Countermeasures in Public Health Emergencies
ResearchCo-Principal Investigator · Awarded by Biomedical Advanced Research and Development Authority · 2024 - 2029Direct-to-family pharmacokinetics intervention for hydroxychloroquine non-adherence in adolescents with systemic lupus erythematosus
ResearchAdvisor · Awarded by National Institutes of Health · 2024 - 2029View All Grants
Education, Training & Certifications
University of North Carolina, Chapel Hill, School of Medicine ·
2012
Ph.D.
Universidad Central de Venezuela (Venezuela) ·
2001
M.D.