https://orcid.org/0000-0002-3311-2944
Overview
Current Appointments & Affiliations
James B. Duke Distinguished Professor of Biochemistry
·
1992 - Present
Biochemistry,
Basic Science Departments
Professor of Biochemistry
·
1991 - Present
Biochemistry,
Basic Science Departments
Recent Publications
Stories from the scientist who changed how we visualize proteins
Journal Article Nature Reviews Chemistry · February 1, 2026 Ahead of her 85th birthday, Jane Richardson, Professor of Biochemistry at Duke University, discussed her life in science from making her own telescope to developing the ribbon diagrams for the 3D structure of proteins. ... Full text CiteNew targets and procedures for validating the valence geometry of nucleic acid structures.
Journal Article Nucleic Acids Res · January 5, 2026 A Working Group consisting of the co-authors of this paper was established in 2020 to re-evaluate the standard valence geometry used for the validation of nucleic acid structure models in the Protein Data Bank (PDB). This Working Group re-examined the depe ... Full text Link to item CiteCategorizing prediction modes within low-pLDDT regions of AlphaFold2 structures: near-predictive, pseudostructure and barbed wire.
Journal Article Acta Crystallogr D Struct Biol · October 1, 2025 AlphaFold2 protein structure predictions are widely available for structural biology uses. These predictions, especially for eukaryotic proteins, frequently contain extensive regions predicted below the pLDDT = 70 level, the rule-of-thumb cutoff for high c ... Full text Link to item CiteRecent Grants
Reimplementing the MolProbity website to be maintained by Phenix & modifying code for Phenix cctbx
ResearchPrincipal Investigator · Awarded by Ernest Orlando Lawrence Berkeley National Laboratory · 2025 - 2026PHENIX: New methods for automation in macromolecular crystallography
ResearchPrincipal Investigator · Awarded by Ernest Orlando Lawrence Berkeley National Laboratory · 2006 - 2023Extending MolProbity Diagnosis & Healing Methods to Empower Better CryoEM & Xray Models at 2.5-4A Resolution, plus Versioned, Redeposited "GEMS" for Important Individual Structures
ResearchInvestigator · Awarded by National Institutes of Health · 2019 - 2023View All Grants
Recent Artistic Works
Ribbon drawing of triose phosphate isomerase 3D protein structure
Drawing January 1, 1981 on Wikimedia Commons
View All Artistic Works
Education
Harvard University ·
1966
M.A.