https://orcid.org/0000-0002-3311-2944
Overview
3D structure of macromolecules; molecular graphics; protein folding and design; all-atom contacts; x-ray crystallography; structure validation.
Current Duke Appointments & Affiliations
James B. Duke Distinguished Professor Emeritus of Biochemistry
·
2026 - Present
Biochemistry,
Basic Science Departments
Professor Emeritus of Biochemistry
·
2026 - Present
Biochemistry,
Basic Science Departments
Recent Scholarly Works
RNAprecis: Prediction of full-detail RNA conformation from the experimentally best-observed sparse parameters.
Journal article PLoS Comput Biol · May 2026 We address the problem of predicting high-detail RNA structure geometry from the information available in low-detail experimental maps. Here, low-detail refers to resolutions ≈ 2.5-3.5Å, where the location of the phosphate groups and the glycosidic bonds c ... Full text Link to item CiteStories from the scientist who changed how we visualize proteins
Journal article Nature Reviews Chemistry · February 1, 2026 Ahead of her 85th birthday, Jane Richardson, Professor of Biochemistry at Duke University, discussed her life in science from making her own telescope to developing the ribbon diagrams for the 3D structure of proteins. ... Full text CiteNew targets and procedures for validating the valence geometry of nucleic acid structures.
Journal article Nucleic Acids Res · January 5, 2026 A Working Group consisting of the co-authors of this paper was established in 2020 to re-evaluate the standard valence geometry used for the validation of nucleic acid structure models in the Protein Data Bank (PDB). This Working Group re-examined the depe ... Full text Link to item CiteRecent Grants
Reimplementing the MolProbity website to be maintained by Phenix & modifying code for Phenix cctbx
ResearchPrincipal Investigator · Awarded by Ernest Orlando Lawrence Berkeley National Laboratory · 2025 - 2026PHENIX: New methods for automation in macromolecular crystallography
ResearchPrincipal Investigator · Awarded by Ernest Orlando Lawrence Berkeley National Laboratory · 2006 - 2023Extending MolProbity Diagnosis & Healing Methods to Empower Better CryoEM & Xray Models at 2.5-4A Resolution, plus Versioned, Redeposited "GEMS" for Important Individual Structures
ResearchInvestigator · Awarded by National Institutes of Health · 2019 - 2023View All Grants
Education
Harvard University ·
1966
M.A.