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Jane Shelby Richardson

James B. Duke Distinguished Professor of Biochemistry
Biochemistry
Duke Box 3711, Durham, NC 27710
132 Nanaline H Duke, Durham, NC 27710

Overview


3D structure of macromolecules; molecular graphics; protein folding and design; all-atom contacts; x-ray crystallography; structure validation.

Current Appointments & Affiliations


James B. Duke Distinguished Professor of Biochemistry · 1992 - Present Biochemistry, Basic Science Departments
Professor of Biochemistry · 1991 - Present Biochemistry, Basic Science Departments

In the News


Published March 15, 2021
Women of Duke Health
Published October 23, 2018
Science's 'Master of Ribbon Diagrams' Celebrates 50 Years at Duke
Published February 9, 2016
Jane Richardson: Visualizing protein structures

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Recent Publications


Cis-nonProline peptides: Genuine occurrences and their functional roles.

Journal Article Protein Sci · June 2025 While cis peptides preceding proline can occur about 5% of the time, cis peptides preceding any other residue ("cis-nonPro" peptides) are an extremely rare feature in protein structures, of considerable importance for two opposite reasons. On one hand, the ... Full text Link to item Cite

Outcomes of the EMDataResource cryo-EM Ligand Modeling Challenge.

Journal Article Nat Methods · July 2024 The EMDataResource Ligand Model Challenge aimed to assess the reliability and reproducibility of modeling ligands bound to protein and protein-nucleic acid complexes in cryogenic electron microscopy (cryo-EM) maps determined at near-atomic (1.9-2.5 Å) reso ... Full text Link to item Cite
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Recent Grants


PHENIX: New methods for automation in macromolecular crystallography

ResearchPrincipal Investigator · Awarded by Ernest Orlando Lawrence Berkeley National Laboratory · 2006 - 2023

Bioinformatics and Computational Biology Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2005 - 2021

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Education, Training & Certifications


Harvard University · 1966 M.A.