More than skin deep: connecting melanocyte pigmentation and angiogenic diseases.

Journal Article (Journal Article)

Epidemiological studies have identified racial differences in susceptibility to numerous diseases, including several ocular and skin diseases characterized by increased vascular growth. In most cases, the specific mechanisms and genetic variants responsible for these differences have remained elusive. In this issue of the JCI, Adini et al. explore a direct connection between skin pigmentation and susceptibility to angiogenic diseases and identify an extracellular matrix protein that is regulated by melanogenesis and potently modulates angiogenesis.

Full Text

Duke Authors

Cited Authors

  • Kontos, CD

Published Date

  • January 2014

Published In

Volume / Issue

  • 124 / 1

Start / End Page

  • 76 - 79

PubMed ID

  • 24355914

Pubmed Central ID

  • PMC3871256

Electronic International Standard Serial Number (EISSN)

  • 1558-8238

Digital Object Identifier (DOI)

  • 10.1172/JCI73559


  • eng

Conference Location

  • United States