Sleep-disordered breathing in patients with heart failure.


Journal Article (Review)

Sleep-disordered breathing (SDB) is prevalent in patients with heart failure, and is associated with increased morbidity and mortality. SDB is proinflammatory, with nocturnal oxygen desaturations and hypercapnia appearing to play a pivotal role in the development of oxidative stress and sympathetic activation. Preliminary data suggest that attention to the diagnosis and management of SDB in patients with heart failure may improve outcomes. Ongoing research into the roles of comorbidities such as SDB as a treatment target may lead to better clinical outcomes and improved quality of life for patients with heart failure.

Full Text

Duke Authors

Cited Authors

  • Mentz, RJ; Fiuzat, M

Published Date

  • April 2014

Published In

Volume / Issue

  • 10 / 2

Start / End Page

  • 243 - 250

PubMed ID

  • 24656103

Pubmed Central ID

  • 24656103

International Standard Serial Number (ISSN)

  • 1551-7136

Digital Object Identifier (DOI)

  • 10.1016/j.hfc.2013.10.001


  • eng

Conference Location

  • United States