Keeping at arm's length during regeneration.


Journal Article (Review)

Regeneration of a lost appendage in adult amphibians and fish is a remarkable feat of developmental patterning. Although the limb or fin may be years removed from its initial creation by an embryonic primordium, the blastema that emerges at the injury site fashions a close mimic of adult form. Central to understanding these events are revealing the cellular origins of new structures, how positional identity is maintained, and the determinants for completion. Each of these topics has been advanced recently, strengthening models for how complex tissue pattern is recalled in the adult context.

Full Text

Duke Authors

Cited Authors

  • Tornini, VA; Poss, KD

Published Date

  • April 28, 2014

Published In

Volume / Issue

  • 29 / 2

Start / End Page

  • 139 - 145

PubMed ID

  • 24780734

Pubmed Central ID

  • 24780734

Electronic International Standard Serial Number (EISSN)

  • 1878-1551

Digital Object Identifier (DOI)

  • 10.1016/j.devcel.2014.04.007


  • eng

Conference Location

  • United States