Melanoma, version 4.2014.

Journal Article (Journal Article)

The NCCN Guidelines for Melanoma provide multidisciplinary recommendations for the management of patients with melanoma. These NCCN Guidelines Insights highlight notable recent updates. Dabrafenib and trametinib, either as monotherapy (category 1) or combination therapy, have been added as systemic options for patients with unresectable metastatic melanoma harboring BRAF V600 mutations. Controversy continues regarding the value of adjuvant radiation for patients at high risk of nodal relapse. This is reflected in the category 2B designation to consider adjuvant radiation following lymphadenectomy for stage III melanoma with clinically positive nodes or recurrent disease.

Full Text

Duke Authors

Cited Authors

  • Coit, DG; Thompson, JA; Andtbacka, R; Anker, CJ; Bichakjian, CK; Carson, WE; Daniels, GA; Daud, A; Dimaio, D; Fleming, MD; Gonzalez, R; Guild, V; Halpern, AC; Hodi, FS; Kelley, MC; Khushalani, NI; Kudchadkar, RR; Lange, JR; Martini, MC; Olszanski, AJ; Ross, MI; Salama, A; Swetter, SM; Tanabe, KK; Trisal, V; Urist, MM; McMillian, NR; Ho, M; National Comprehensive Cancer Network,

Published Date

  • May 2014

Published In

Volume / Issue

  • 12 / 5

Start / End Page

  • 621 - 629

PubMed ID

  • 24812131

Electronic International Standard Serial Number (EISSN)

  • 1540-1413

Digital Object Identifier (DOI)

  • 10.6004/jnccn.2014.0066


  • eng

Conference Location

  • United States