April Kelly Scott Salama
Associate Professor of Medicine
Current Appointments & Affiliations
- Associate Professor of Medicine, Medicine, Medical Oncology, Medicine 2021
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2010
Contact Information
- 30 Duke Medicine Circle, 25177 Morris Bldg, Durham, NC 27710
- DUMC 3198, Durham, NC 27710
- Background
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Education, Training, & Certifications
- Hematology/Oncology, The University of Chicago 2007 - 2010
- Internal Medicine, The University of Chicago 2004 - 2007
- M.D., University of North Carolina - Chapel Hill 2004
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Previous Appointments & Affiliations
- Associate Professor of Medicine, Medicine, Medical Oncology, Medicine 2018 - 2021
- Assistant Professor of Medicine, Medicine, Medical Oncology, Medicine 2013 - 2018
- Medical Instructor in the Department of Medicine, Medicine, Medical Oncology, Medicine 2011 - 2013
- Instructor Temporary in the Department of Medicine, Medicine, Medical Oncology, Medicine 2010
- Recognition
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In the News
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JUL 12, 2021 School of Medicine Magnify
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- Research
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Selected Grants
- A study of SGN BB228 in advanced melanoma and other solid tumors awarded by Seagen, Inc 2023 - 2028
- Regeneron R3767-ONC awarded by Regeneron Pharmaceuticals, Inc. 2023 - 2027
- A Study of Dapansutrile Plus Pembrolizumab in Patients with PD-1 Refractory Advanced Melanoma awarded by Olatec Therapeutics LLC 2022 - 2027
- IDE196 in Metastatic Uveal or Non-Uveal Melanoma with GNAQ/11 Mutations or PRKC Fusions (IDEAYA) awarded by IDEAYA Biosciences 2022 - 2026
- A Phase 3, Randomized, Double-blind Study of Adjuvant Immunotherapy with Relatlimab and Nivolumab Fixed-dose Combination versus Nivolumab Monotherapy after Complete Resection of Stage III-IV Melanoma awarded by Bristoll Myers Squibb 2022 - 2026
- Adjuvant Nivolumab or Ipilimumab + Nivolumab Determined by Pathological Response to a Single Dose of Neoadjuvant Nivolumab awarded by University of Pennsylvania 2021 - 2026
- A Study of Dapansutrile Plus Pembrolizumab in Patients with PD-1 Refractory Advanced Melanoma awarded by Merck & Co., Inc. 2022 - 2026
- An Open-label, Phase 2 Basket Study of SEA-CD40 Combination Therapies in Advanced Malignancies awarded by Seattle Genetics, Inc 2021 - 2026
- A Phase 3, Randomized, Open-label Study to Compare Adjuvant Immunotherapy of Bempegaldesleukin Combined with Nivolumab Versus Nivolumab After Complete Resection of Melanoma in Patients at High Risk for Recurrence (PIVOT-12) awarded by Nektar Therapeutics 2021 - 2026
- A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants With Melanoma (KEYMAKER-U02): Substudy 02B awarded by Merck Sharp & Dohme 2021 - 2026
- A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants with Melanoma (KEYNOTE-U02): Substudy 02A awarded by Merck Sharp & Dohme 2021 - 2026
- A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants With Melanoma (KEYMAKER-U02): Substudy 02D awarded by Merck Sharp & Dohme 2021 - 2026
- A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants with Melanoma (KEYNOTE-U02): Substudy 02C awarded by Merck Sharp & Dohme 2021 - 2026
- A Phase 3, Randomized, Double-Blind Study of Adjuvant Immunotherapy with Nivolumab versus Placebo after Complete Resection of Stage IIB/C Melanoma (CheckMate 76K: CHECKpoint pathway and nivoluMAb clinical Trial Evaluation 76K) awarded by Bristol-Myers Squibb Company 2021 - 2026
- BMS Rollover (CA2098TT) awarded by Bristol-Myers Squibb Company 2019 - 2024
- Clinical Biomarker Study of the Tumor NLRP3 Inflammasome and its Role in Anti-PD-1 Immunotherapy Resistance awarded by Conquer Cancer Foundation 2021 - 2024
- A Multicenter, Open label, Phase III Extension Trial to Study the Long-term Safety and Efficacy in Participants with Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab Trial. awarded by Merck Sharp & Dohme 2019 - 2023
- BMS CA209-238-0025 A Phase 3, Randomized, Double-blind Study of Adjuvant Immunotherapy with Nivolumab versus Ipilimumab after Complete Resection of Stage IIIb/c or Stage IV Melanoma in Subjects who are at high risk for recurrence. awarded by The Bristol-Myers/Sanofi Pharmaceuticals, Inc. Partnership 2015 - 2023
- A Phase Ib/II Open-label, Multi-center Study of the Safety and Efficacy of IMCgp100 in Combination with Durvalumab (MEDI4736) or Tremelimumab or the Combination of Durvalumab and Tremelimumab Compared to IMCgp100 Alone in Patients with Advanced Melan awarded by Immunocore Limited 2016 - 2023
- Duke-UNC-Wash U Partnership for Early Phase Clinical Trials in Cancer awarded by National Institutes of Health 2014 - 2023
- A Phase II Randomized, Open-label, Multi-center Study of the Safety and Efficacy of IMCgp100 Compared with Investigator's Choice in HLA-A*0201 Positive Patients with Previously Untreated Advanced Uveal Melanoma awarded by Immunocore Limited 2017 - 2022
- CA209204 A Multi-Center Phase 2 Open-Label Study to Evaluate Safety and Efficacy in Subjects with Melanoma Metastatic to the Brain treated with Nivolumab in Combination with Ipilimumab followed by awarded by Bristol-Myers Squibb Company 2015 - 2021
- A Phase 2, Open-Label, Randomized, Multicenter Trial of Encorafenib + Binimetinib Evaluating a Standard-dose and a High-dose Regimen in Patients With BRAFV600-Mutant Melanoma Brain Metastasis awarded by Array BioPharma Inc 2019 - 2021
- A US Multi-Site Observational Study in Patients with Unresectable and Metastatic Melanoma: The OPTIMIzE Study awarded by Bristol-Myers Squibb Company 2016 - 2021
- DV3-MEL-01 awarded by Dynavax Technologies Corporation 2017 - 2020
- Collaborative Success: Expanding Options for Patients with Melanoma awarded by National Institutes of Health 1997 - 2019
- A Phase 3, Randomized Study of Adjuvant Immunotherapy with Nivolumab Combined with Ipilimumab versus Nivolumab Monotherapy after Complete Resection of Stage IIIb/c/d or Stage IV Melanoma awarded by Bristol-Myers Squibb Company 2017 - 2019
- An open label, multicenter, dose-escalation, phase 1B/2 study of the safety, efficacy, pharmacodynamics, and pharmacokinetics of RTA 408 in combination with IPILIMUMAB in the treatment of patients with unresectable or metastatic melanoma awarded by Reata Pharmaceuticals, Inc. 2014 - 2019
- INCB 24360-208 A Phase 1/2, Open-Label, Dose-Escalation, Safety, Tolerability, and Efficacy Study of Epacadostat and Nivolumab in Combination With Immune Therapies in Subjects With Advanced or Metastatic Malignancies (ECHO-208) awarded by Incyte Corporation 2018 - 2019
- A Phase II Study of Glembatumumab Vedotin, an Anti-gpNMB Antibody -Drug Conjugate, in Patients with Advanced Melanoma awarded by Celldex Therapeutics, Inc. 2015 - 2019
- A phase Ii trial of Neoadjuvant Ipilimumab follwed by Melphalan (L-PAM) via isolated Limb infusion (ILI) for patients with unresectable In-transit Extremity awarded by Bristol-Myers Squibb Company 2014 - 2018
- Expanded access of MK-3475 in metastatic melanoma patients with limited to no treatment options. awarded by Merck Sharp & Dohme 2014 - 2015
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External Relationships
- Bristol Myers Squibb
- Exact Sciences
- Iovance
- Novartis
- Pfizer Inc.
- Regeneron Pharmaceuticals
- Replimmune
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Sperduto, Paul W., April K. S. Salama, and Carey Anders. “Progress for Patients with Melanoma Brain Metastases.” Neuro Oncol, March 8, 2023. https://doi.org/10.1093/neuonc/noad050.Full Text Link to Item
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Theivanthiran, Balamayooran, Nagendra Yarla, Tarek Haykal, Y-Van Nguyen, Linda Cao, Michelle Ferreira, Alisha Holtzhausen, et al. “Tumor-intrinsic NLRP3-HSP70-TLR4 axis drives premetastatic niche development and hyperprogression during anti-PD-1 immunotherapy.” Sci Transl Med 14, no. 672 (November 23, 2022): eabq7019. https://doi.org/10.1126/scitranslmed.abq7019.Full Text Link to Item
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Beasley, Georgia M., Michael C. Brown, Norma E. Farrow, Karenia Landa, Rami N. Al-Rohil, Maria Angelica Selim, Aaron D. Therien, et al. “Multimodality analysis confers a prognostic benefit of a T-cell infiltrated tumor microenvironment and peripheral immune status in patients with melanoma.” J Immunother Cancer 10, no. 9 (September 2022). https://doi.org/10.1136/jitc-2022-005052.Full Text Link to Item
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Rhodin, Kristen E., Elizabeth M. Gaughan, Vignesh Raman, April K. Salama, Brent A. Hanks, Riddhishkumar Shah, Douglas S. Tyler, Craig L. Slingluff, and Georgia M. Beasley. “Multicenter Experience with Neoadjuvant Therapy in Melanoma Highlights Heterogeneity in Contemporary Practice.” Ann Surg, July 7, 2022. https://doi.org/10.1097/SLA.0000000000005459.Full Text Link to Item
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Oswalt, Cameron J., Rami N. Al-Rohil, Bala Theivanthiran, Tarek Haykal, April K. S. Salama, Nicholas C. DeVito, Alisha Holtzhausen, Dennis C. Ko, and Brent A. Hanks. “Identification of a Germline Pyrin Variant in a Metastatic Melanoma Patient With Multiple Spontaneous Regressions and Immune-related Adverse Events.” J Immunother 45, no. 6 (July 2022): 284–90. https://doi.org/10.1097/CJI.0000000000000425.Full Text Open Access Copy Link to Item
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Sarver, Melissa, Michael C. Brown, Kristen E. Rhodin, April K. S. Salama, and Georgia M. Beasley. “Predictive factors of neoadjuvant immune checkpoint blockade in melanoma.” Hum Vaccin Immunother 18, no. 3 (May 31, 2022): 1943987. https://doi.org/10.1080/21645515.2021.1943987.Full Text Link to Item
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Kennedy, Lucy Boyce, and April K. S. Salama. “A Marathon Not a Sprint: Improving Outcomes for Patients With Metastatic Melanoma in 2022 and Beyond.” Jco Oncol Pract 18, no. 5 (May 2022): 353–54. https://doi.org/10.1200/OP.22.00012.Full Text Link to Item
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Nathan, Paul, Jessica C. Hassel, Piotr Rutkowski, Jean-Francois Baurain, Marcus O. Butler, Max Schlaak, Ryan J. Sullivan, et al. “Overall Survival Benefit with Tebentafusp in Metastatic Uveal Melanoma.” N Engl J Med 385, no. 13 (September 23, 2021): 1196–1206. https://doi.org/10.1056/NEJMoa2103485.Full Text Link to Item
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Dikshit, Anushka, Junqi Lu, Amy E. Ford, Simone Degan, Yingai J. Jin, Huiying Sun, Amanda Nichols, et al. “Potential Utility of Synthetic D-Lactate Polymers in Skin Cancer.” Jid Innov 1, no. 3 (September 2021): 100043. https://doi.org/10.1016/j.xjidi.2021.100043.Full Text Link to Item
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DeVito, Nicholas C., Michael Sturdivant, Balamayooran Thievanthiran, Christine Xiao, Michael P. Plebanek, April K. S. Salama, Georgia M. Beasley, et al. “Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy.” Cell Rep 35, no. 5 (May 4, 2021): 109071. https://doi.org/10.1016/j.celrep.2021.109071.Full Text Open Access Copy Link to Item
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Beasley, Georgia M., Smita K. Nair, Norma E. Farrow, Karenia Landa, Maria Angelica Selim, Carol Ann Wiggs, Sin-Ho Jung, et al. “Phase I trial of intratumoral PVSRIPO in patients with unresectable, treatment-refractory melanoma.” J Immunother Cancer 9, no. 4 (April 2021). https://doi.org/10.1136/jitc-2020-002203.Full Text Link to Item
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Swetter, Susan M., John A. Thompson, Mark R. Albertini, Christopher A. Barker, Joel Baumgartner, Genevieve Boland, Bartosz Chmielowski, et al. “NCCN Guidelines® Insights: Melanoma: Cutaneous, Version 2.2021.” J Natl Compr Canc Netw 19, no. 4 (April 1, 2021): 364–76. https://doi.org/10.6004/jnccn.2021.0018.Full Text Link to Item
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Salama, April K. S., Manisha Palta, Christel N. Rushing, M Angelica Selim, Kristen N. Linney, Brian G. Czito, David S. Yoo, et al. “Ipilimumab and Radiation in Patients with High-risk Resected or Regionally Advanced Melanoma.” Clin Cancer Res 27, no. 5 (March 1, 2021): 1287–95. https://doi.org/10.1158/1078-0432.CCR-20-2452.Full Text Link to Item
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Patrinely, J Randall, Ben McGuigan, Sunandana Chandra, Sarah E. Fenton, Akansha Chowdhary, Lucy B. Kennedy, Meghan J. Mooradian, et al. “A multicenter characterization of hepatitis associated with immune checkpoint inhibitors.” Oncoimmunology 10, no. 1 (February 8, 2021): 1875639. https://doi.org/10.1080/2162402X.2021.1875639.Full Text Link to Item
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Haugh, Alexandra M., April K. S. Salama, and Douglas B. Johnson. “Advanced Melanoma: Resistance Mechanisms to Current Therapies.” Hematol Oncol Clin North Am 35, no. 1 (February 2021): 111–28. https://doi.org/10.1016/j.hoc.2020.09.005.Full Text Link to Item
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Dietz, Hilary, Sophia C. Weinmann, and April K. Salama. “Checkpoint Inhibitors in Melanoma Patients with Underlying Autoimmune Disease.” Cancer Manag Res 13 (2021): 8199–8208. https://doi.org/10.2147/CMAR.S283217.Full Text Link to Item
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Shen, Erica, Amanda E. D. Van Swearingen, Meghan J. Price, Ketan Bulsara, Roeland G. W. Verhaak, César Baëta, Brice D. Painter, et al. “A Need for More Molecular Profiling in Brain Metastases.” Front Oncol 11 (2021): 785064. https://doi.org/10.3389/fonc.2021.785064.Full Text Link to Item
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Farrow, Norma E., Megan C. Turner, April K. S. Salama, and Georgia M. Beasley. “Overall Survival Improved for Contemporary Patients with Melanoma: A 2004-2015 National Cancer Database Analysis.” Oncol Ther 8, no. 2 (December 2020): 261–75. https://doi.org/10.1007/s40487-020-00117-1.Full Text Link to Item
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Ravichandran, Surya, Neel Nath, David C. Jones, Gabriel Li, Visakha Suresh, Adam K. Brys, Brent A. Hanks, et al. “The utility of initial staging PET-CT as a baseline scan for surveillance imaging in stage II and III melanoma.” Surg Oncol 35 (December 2020): 533–39. https://doi.org/10.1016/j.suronc.2020.10.018.Full Text Link to Item
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Salama, April K. S., Shuli Li, Erin R. Macrae, Jong-In Park, Edith P. Mitchell, James A. Zwiebel, Helen X. Chen, et al. “Dabrafenib and Trametinib in Patients With Tumors With BRAFV600E Mutations: Results of the NCI-MATCH Trial Subprotocol H.” J Clin Oncol 38, no. 33 (November 20, 2020): 3895–3904. https://doi.org/10.1200/JCO.20.00762.Full Text Link to Item
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Hu, Janice B., Surya Ravichandran, Christel Rushing, Georgia M. Beasley, Brent A. Hanks, Sin-Ho Jung, April K. S. Salama, Lisa Ho, and Paul J. Mosca. “Higher BMI, But Not Sarcopenia, Is Associated With Pembrolizumab-related Toxicity in Patients With Advanced Melanoma.” Anticancer Res 40, no. 9 (September 2020): 5245–54. https://doi.org/10.21873/anticanres.14528.Full Text Link to Item
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Dalal, Nicole H., Fumiko Chino, Hannah Williamson, Georgia M. Beasley, April K. S. Salama, and Manisha Palta. “Mind the gap: Gendered publication trends in oncology.” Cancer 126, no. 12 (June 15, 2020): 2859–65. https://doi.org/10.1002/cncr.32818.Full Text Link to Item
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Theivanthiran, Balamayoora, Kathy S. Evans, Nicholas C. DeVito, Michael Plebanek, Michael Sturdivant, Luke P. Wachsmuth, April Ks Salama, et al. “A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti-PD-1 immunotherapy.” J Clin Invest 130, no. 5 (May 1, 2020): 2570–86. https://doi.org/10.1172/JCI133055.Full Text Link to Item
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Moravan, Michael J., Peter E. Fecci, Carey K. Anders, Jeffrey M. Clarke, April K. S. Salama, Justus D. Adamson, Scott R. Floyd, et al. “Current multidisciplinary management of brain metastases.” Cancer 126, no. 7 (April 1, 2020): 1390–1406. https://doi.org/10.1002/cncr.32714.Full Text Link to Item
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Kennedy, Lucy Boyce, and April K. S. Salama. “A review of cancer immunotherapy toxicity.” Ca Cancer J Clin 70, no. 2 (March 2020): 86–104. https://doi.org/10.3322/caac.21596.Full Text Link to Item
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Rao, P Kumar, Christopher Barker, Daniel G. Coit, Richard W. Joseph, Miguel Materin, Ramesh Rengan, Jeffrey Sosman, et al. “NCCN Guidelines Insights: Uveal Melanoma, Version 1.2019.” J Natl Compr Canc Netw 18, no. 2 (February 2020): 120–31. https://doi.org/10.6004/jnccn.2020.0007.Full Text Link to Item
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Wierda, William G., John C. Byrd, Jeremy S. Abramson, Syed F. Bilgrami, Greg Bociek, Danielle Brander, Jennifer Brown, et al. “Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 4.2020, NCCN Clinical Practice Guidelines in Oncology.” J Natl Compr Canc Netw 18, no. 2 (February 2020): 185–217. https://doi.org/10.6004/jnccn.2020.0006.Full Text Link to Item
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Kennedy, Lucy Boyce, and April K. S. Salama. “A Review of Immune-Mediated Adverse Events in Melanoma.” Oncol Ther 7, no. 2 (December 2019): 101–20. https://doi.org/10.1007/s40487-019-0096-8.Full Text Link to Item
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Sankey, Eric W., Vadim Tsvankin, Matthew M. Grabowski, Gautam Nayar, Kristen A. Batich, Aida Risman, Cosette D. Champion, April K. S. Salama, C Rory Goodwin, and Peter E. Fecci. “Operative and peri-operative considerations in the management of brain metastasis.” Cancer Med 8, no. 16 (November 2019): 6809–31. https://doi.org/10.1002/cam4.2577.Full Text Link to Item
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Mowery, Yvonne M., Kirtesh Patel, Mudit Chowdhary, Christel N. Rushing, Kingshuk Roy Choudhury, Jared R. Lowe, Adam C. Olson, et al. “Retrospective analysis of safety and efficacy of anti-PD-1 therapy and radiation therapy in advanced melanoma: A bi-institutional study.” Radiother Oncol 138 (September 2019): 114–20. https://doi.org/10.1016/j.radonc.2019.06.013.Full Text Link to Item
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Amaria, Rodabe N., Alexander M. Menzies, Elizabeth M. Burton, Richard A. Scolyer, Michael T. Tetzlaff, Robert Antdbacka, Charlotte Ariyan, et al. “Neoadjuvant systemic therapy in melanoma: recommendations of the International Neoadjuvant Melanoma Consortium.” Lancet Oncol 20, no. 7 (July 2019): e378–89. https://doi.org/10.1016/S1470-2045(19)30332-8.Full Text Link to Item
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Leaf, Rebecca Karp, Christopher Ferreri, Deepa Rangachari, James Mier, Wesley Witteles, George Ansstas, Theodora Anagnostou, et al. “Clinical and laboratory features of autoimmune hemolytic anemia associated with immune checkpoint inhibitors.” Am J Hematol 94, no. 5 (May 2019): 563–74. https://doi.org/10.1002/ajh.25448.Full Text Link to Item
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Coit, Daniel G., John A. Thompson, Mark R. Albertini, Christopher Barker, William E. Carson, Carlo Contreras, Gregory A. Daniels, et al. “Cutaneous Melanoma, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology.” J Natl Compr Canc Netw 17, no. 4 (April 1, 2019): 367–402. https://doi.org/10.6004/jnccn.2019.0018.Full Text Link to Item
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Ott, Patrick A., Anna C. Pavlick, Douglas B. Johnson, Lowell L. Hart, Jeffrey R. Infante, Jason J. Luke, Jose Lutzky, et al. “A phase 2 study of glembatumumab vedotin, an antibody-drug conjugate targeting glycoprotein NMB, in patients with advanced melanoma.” Cancer 125, no. 7 (April 1, 2019): 1113–23. https://doi.org/10.1002/cncr.31892.Full Text Link to Item
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Puza, Charles J., Elizabeth Schell Bressler, Alicia M. Terando, John Harrison Howard, Michael C. Brown, Brent Hanks, April K. S. Salama, and Georgia M. Beasley. “The Emerging Role of Surgery for Patients With Advanced Melanoma Treated With Immunotherapy.” J Surg Res 236 (April 2019): 209–15. https://doi.org/10.1016/j.jss.2018.11.045.Full Text Link to Item
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Kwak, Minyoung, Norma E. Farrow, April K. S. Salama, Paul J. Mosca, Brent A. Hanks, Craig L. Slingluff, and Georgia M. Beasley. “Updates in adjuvant systemic therapy for melanoma.” J Surg Oncol 119, no. 2 (January 2019): 222–31. https://doi.org/10.1002/jso.25298.Full Text Link to Item
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Grant, Michael J., Nicholas DeVito, and April K. S. Salama. “Checkpoint inhibitor use in two heart transplant patients with metastatic melanoma and review of high-risk populations.” Melanoma Manag 5, no. 4 (December 2018): MMT10. https://doi.org/10.2217/mmt-2018-0004.Full Text Link to Item
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Owonikoko, T. K., K. P. Papadopoulos, M. Gil-Martin, V. Moreno, A. K. Salama, E. Calvo, H. Safran, et al. “Phase I study of cemiplimab, a human monoclonal anti-PD-1, in patients with unresectable locally advanced or metastatic cutaneous squamous cell carcinoma (CSCC): Longer follow-up efficacy and safety data.” Ann Oncol 29 Suppl 8 (October 2018): viii461–62. https://doi.org/10.1093/annonc/mdy289.048.Full Text Link to Item
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Ribas, A., I. Mehmi, T. Medina, C. Lao, S. Kummar, A. Amin, S. Deva, et al. “Phase Ib/II study of the combination of SD-101 and pembrolizumab in patients with advanced melanoma who had progressive disease on or after prior anti-PD-1 therapy.” Ann Oncol 29 Suppl 8 (October 2018): viii451–52. https://doi.org/10.1093/annonc/mdy289.021.Full Text Link to Item
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Tan, Irena, Michael Malinzak, and April K. S. Salama. “Delayed onset of neurosarcoidosis after concurrent ipilimumab/nivolumab therapy.” J Immunother Cancer 6, no. 1 (July 31, 2018): 77. https://doi.org/10.1186/s40425-018-0390-2.Full Text Link to Item
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Barker, Christopher A., and April K. Salama. “New NCCN Guidelines for Uveal Melanoma and Treatment of Recurrent or Progressive Distant Metastatic Melanoma.” J Natl Compr Canc Netw 16, no. 5S (May 2018): 646–50. https://doi.org/10.6004/jnccn.2018.0042.Full Text Link to Item
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Maio, Michele, Karl Lewis, Lev Demidov, Mario Mandalà, Igor Bondarenko, Paolo A. Ascierto, Christopher Herbert, et al. “Adjuvant vemurafenib in resected, BRAFV600 mutation-positive melanoma (BRIM8): a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial.” Lancet Oncol 19, no. 4 (April 2018): 510–20. https://doi.org/10.1016/S1470-2045(18)30106-2.Full Text Link to Item
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Bhatti, M. T., and A. K. S. Salama. “Neuro-ophthalmic side effects of molecularly targeted cancer drugs.” Eye (Lond) 32, no. 2 (February 2018): 287–301. https://doi.org/10.1038/eye.2017.222.Full Text Link to Item
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Clarke, Jeffrey M., Daniel J. George, Stacey Lisi, and April K. S. Salama. “Immune Checkpoint Blockade: The New Frontier in Cancer Treatment.” Target Oncol 13, no. 1 (February 2018): 1–20. https://doi.org/10.1007/s11523-017-0549-7.Full Text Link to Item
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Hamid, Omid, Igor Puzanov, Reinhard Dummer, Jacob Schachter, Adil Daud, Dirk Schadendorf, Christian Blank, et al. “Final analysis of a randomised trial comparing pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory advanced melanoma.” Eur J Cancer 86 (November 2017): 37–45. https://doi.org/10.1016/j.ejca.2017.07.022.Full Text Link to Item
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Rossfeld, Kara, Erinn M. Hade, Alexandra Gangi, Matthew Perez, Emily N. Kinsey, Joanna Grabska, Ashley Ederle, et al. “Metastatic melanoma patients' sensitivity to ipilimumab cannot be predicted by tumor characteristics.” Int J Surg Oncol (N Y) 2, no. 9 (October 2017): e43. https://doi.org/10.1097/IJ9.0000000000000043.Full Text Link to Item
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Beasley, Georgia M., Yinin Hu, Linda Youngwirth, Randall P. Scheri, April K. Salama, Kara Rossfeld, Syed Gardezi, et al. “Sentinel Lymph Node Biopsy for Recurrent Melanoma: A Multicenter Study.” Ann Surg Oncol 24, no. 9 (September 2017): 2728–33. https://doi.org/10.1245/s10434-017-5883-6.Full Text Link to Item
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Turner, Megan C., Kara Rossfeld, April K. S. Salama, Douglas Tyler, and Georgia Beasley. “Can binimetinib, encorafenib and masitinib be more efficacious than currently available mutation-based targeted therapies for melanoma treatment?” Expert Opin Pharmacother 18, no. 5 (April 2017): 487–95. https://doi.org/10.1080/14656566.2017.1299710.Full Text Link to Item
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Kinsey, E. N., and A. K. S. Salama. “Metastatic uveal melanoma-A review of current therapies and future directions.” European Oncology and Haematology 13, no. 2 (January 1, 2017): 100–106. https://doi.org/10.17925/OHR.2017.13.02.100.Full Text
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Force, Jeremy, and April Ks Salama. “First-line treatment of metastatic melanoma: role of nivolumab.” Immunotargets Ther 6 (2017): 1–10. https://doi.org/10.2147/ITT.S110479.Full Text Open Access Copy Link to Item
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Gangadhar, Tara C., Wen-Jen Hwu, Michael A. Postow, Omid Hamid, Adil Daud, Roxana Dronca, Richard Joseph, et al. “Efficacy and Safety of Pembrolizumab in Patients Enrolled in KEYNOTE-030 in the United States: An Expanded Access Program.” J Immunother 40, no. 9 (2017): 334–40. https://doi.org/10.1097/CJI.0000000000000186.Full Text Link to Item
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Salama, A. K. S., and S. J. Moschos. “Next steps in immuno-oncology: enhancing antitumor effects through appropriate patient selection and rationally designed combination strategies.” Ann Oncol 28, no. 1 (January 1, 2017): 57–74. https://doi.org/10.1093/annonc/mdw534.Full Text Link to Item
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Salama, Atef Kamel. “Comparison between ketamine and hyoscine for the management of postoperative catheter-related bladder discomfort: A randomized controlled double-blind study.” J Anaesthesiol Clin Pharmacol 33, no. 1 (2017): 76–80. https://doi.org/10.4103/0970-9185.202191.Full Text Link to Item
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Shoushtari, Alexander N., Rodrigo R. Munhoz, Deborah Kuk, Patrick A. Ott, Douglas B. Johnson, Katy K. Tsai, Suthee Rapisuwon, et al. “The efficacy of anti-PD-1 agents in acral and mucosal melanoma.” Cancer 122, no. 21 (November 15, 2016): 3354–62. https://doi.org/10.1002/cncr.30259.Full Text Link to Item
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Schadendorf, Dirk, Reinhard Dummer, Axel Hauschild, Caroline Robert, Omid Hamid, Adil Daud, Alfons van den Eertwegh, et al. “Health-related quality of life in the randomised KEYNOTE-002 study of pembrolizumab versus chemotherapy in patients with ipilimumab-refractory melanoma.” Eur J Cancer 67 (November 2016): 46–54. https://doi.org/10.1016/j.ejca.2016.07.018.Full Text Link to Item
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Hodi, F Stephen, Jason Chesney, Anna C. Pavlick, Caroline Robert, Kenneth F. Grossmann, David F. McDermott, Gerald P. Linette, et al. “Combined nivolumab and ipilimumab versus ipilimumab alone in patients with advanced melanoma: 2-year overall survival outcomes in a multicentre, randomised, controlled, phase 2 trial.” Lancet Oncol 17, no. 11 (November 2016): 1558–68. https://doi.org/10.1016/S1470-2045(16)30366-7.Full Text Link to Item
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Salama, A. K. S., and S. J. Moschos. “Next Steps in Immuno-Oncology: Enhancing Antitumor Effects Through Appropriate Patient Selection and Rationally Designed Combination Strategies.” Ann Oncol, October 13, 2016. https://doi.org/10.1093/annonc/mdw534.Full Text Link to Item
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Hamid, O., I. Puzanov, R. Dummer, J. Schachter, A. Daud, D. Schadendorf, C. Blank, et al. “Final overall survival for KEYNOTE-002: pembrolizumab (pembro) versus investigator-choice chemotherapy (chemo) for ipilimumab (ipi)-refractory melanoma.” Annals of Oncology 27 (October 1, 2016): vi379. https://doi.org/10.1093/annonc/mdw379.02.Full Text
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Choe, Jennifer H., Brian J. Andonian, Grace J. Kim, and April Ks Salama. “Autoimmune meningoencephalitis in a melanoma patient treated with ipilimumab.” Immunotherapy 8, no. 10 (October 2016): 1163–67. https://doi.org/10.2217/imt-2016-0058.Full Text Link to Item
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Qin, Rosie, Adam Olson, Bhavana Singh, Samantha Thomas, Steven Wolf, Nrupen A. Bhavsar, Brent A. Hanks, Joseph K. Salama, and April K. S. Salama. “Safety and Efficacy of Radiation Therapy in Advanced Melanoma Patients Treated With Ipilimumab.” Int J Radiat Oncol Biol Phys 96, no. 1 (September 1, 2016): 72–77. https://doi.org/10.1016/j.ijrobp.2016.04.017.Full Text Link to Item
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Olson, Adam C., Samantha Thomas, Rosie Qin, Bhavana Singh, Joseph K. Salama, John Kirkpatrick, and April Ks Salama. “Outcomes and toxicity of stereotactic radiosurgery for melanoma brain metastases in patients receiving ipilimumab.” Melanoma Manag 3, no. 3 (September 2016): 177–86. https://doi.org/10.2217/mmt-2016-0004.Full Text Link to Item
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Sammons, Sarah, Donita Brady, Linda Vahdat, and April Ks Salama. “Copper suppression as cancer therapy: the rationale for copper chelating agents in BRAFV600 mutated melanoma.” Melanoma Manag 3, no. 3 (September 2016): 207–16. https://doi.org/10.2217/mmt-2015-0005.Full Text Link to Item
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Coit, Daniel G., John A. Thompson, Alain Algazi, Robert Andtbacka, Christopher K. Bichakjian, William E. Carson, Gregory A. Daniels, et al. “NCCN Guidelines Insights: Melanoma, Version 3.2016.” J Natl Compr Canc Netw 14, no. 8 (August 2016): 945–58. https://doi.org/10.6004/jnccn.2016.0101.Full Text Link to Item
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Farber, S Harrison, Vadim Tsvankin, Jessica L. Narloch, Grace J. Kim, April K. S. Salama, Gordana Vlahovic, Kimberly L. Blackwell, John P. Kirkpatrick, and Peter E. Fecci. “Embracing rejection: Immunologic trends in brain metastasis.” Oncoimmunology 5, no. 7 (July 2016): e1172153. https://doi.org/10.1080/2162402X.2016.1172153.Full Text Link to Item
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Salama, April K. S., Michael A. Postow, and Joseph K. Salama. “Irradiation and immunotherapy: From concept to the clinic.” Cancer 122, no. 11 (June 1, 2016): 1659–71. https://doi.org/10.1002/cncr.29889.Full Text Link to Item
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Brys, Adam K., Lubna Bhatti, Mustafa R. Bashir, Tracy A. Jaffe, Georgia M. Beasley, Neel S. Nath, April K. S. Salama, Douglas S. Tyler, and Paul J. Mosca. “Computed Tomography-Based Limb Volume Measurements for Isolated Limb Infusion in Melanoma.” Ann Surg Oncol 23, no. 4 (April 2016): 1090–95. https://doi.org/10.1245/s10434-015-4972-7.Full Text Link to Item
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Coit, Daniel G., John A. Thompson, Alain Algazi, Robert Andtbacka, Christopher K. Bichakjian, William E. Carson, Gregory A. Daniels, et al. “Melanoma, Version 2.2016, NCCN Clinical Practice Guidelines in Oncology.” J Natl Compr Canc Netw 14, no. 4 (April 2016): 450–73. https://doi.org/10.6004/jnccn.2016.0051.Full Text Link to Item
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Barina, Andrew R., Mustafa R. Bashir, Brandon A. Howard, Brent A. Hanks, April K. Salama, and Tracy A. Jaffe. “Isolated recto-sigmoid colitis: a new imaging pattern of ipilimumab-associated colitis.” Abdom Radiol (Ny) 41, no. 2 (February 2016): 207–14. https://doi.org/10.1007/s00261-015-0560-3.Full Text Link to Item
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Singh, Bhavana P., and April K. S. Salama. “Updates in Therapy for Advanced Melanoma.” Cancers (Basel) 8, no. 1 (January 15, 2016). https://doi.org/10.3390/cancers8010017.Full Text Link to Item
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Kinsey, E. N., N. DeVito, W. Barrow, S. A. Myers, and A. K. S. Salama. “Paraneoplastic Production of Granulocyte-macrophage Colony-stimulating Factor and Granulocyte Colony-stimulating Factor in a Case of Rapidly Progressing Cutaneous Squamous Cell Carcinoma.” Clinical Skin Cancer 1, no. 1 (January 1, 2016): 20–22. https://doi.org/10.1016/j.clsc.2016.11.004.Full Text
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Romain, P. E. S., A. K. S. Salama, N. Lynn Ferguson, and R. A. Burbridge. “Ipilimumab-Associated lymphocytic colitis: A case report.” Translational Gastroenterology and Hepatology 5, no. 1 (January 1, 2016): 44–46. https://doi.org/10.3978/j.issn.2224-4778.2015.10.11.Full Text
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Salama, Ahmed K., Khaled A. Osman, and Neama Abdel-Razeek Gouda. “Remediation of lead and cadmium-contaminated soils.” Int J Phytoremediation 18, no. 4 (2016): 364–67. https://doi.org/10.1080/15226514.2015.1109597.Full Text Link to Item
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Amin, Asim, David H. Lawson, April K. S. Salama, Henry B. Koon, Troy Guthrie, Sajeve S. Thomas, Steven J. O’Day, et al. “Phase II study of vemurafenib followed by ipilimumab in patients with previously untreated BRAF-mutated metastatic melanoma.” J Immunother Cancer 4 (2016): 44. https://doi.org/10.1186/s40425-016-0148-7.Full Text Link to Item
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Lovly, Christine M., April K. S. Salama, and Ravi Salgia. “Tumor Heterogeneity and Therapeutic Resistance.” Am Soc Clin Oncol Educ Book 35 (2016): e585–93. https://doi.org/10.1200/EDBK_158808.Full Text Link to Item
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Lowe, Jared R., Daniel J. Perry, April K. S. Salama, Clayton E. Mathews, Larry G. Moss, and Brent A. Hanks. “Genetic risk analysis of a patient with fulminant autoimmune type 1 diabetes mellitus secondary to combination ipilimumab and nivolumab immunotherapy.” J Immunother Cancer 4 (2016): 89. https://doi.org/10.1186/s40425-016-0196-z.Full Text Open Access Copy Link to Item
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Salama, Atef Kamal, and Hassan Mohamed Ali. “Comparative study of hyoscine doses as antisialagogue for patients receiving ketofol sedation undergoing colonoscopy procedures.” Anesth Essays Res 10, no. 1 (2016): 94–97. https://doi.org/10.4103/0259-1162.164735.Full Text Link to Item
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Howie, Lynn J., Douglas S. Tyler, and April K. S. Salama. “Neoadjuvant use of ipilimumab in locally advanced melanoma.” J Surg Oncol 112, no. 8 (December 2015): 841–43. https://doi.org/10.1002/jso.24079.Full Text Link to Item
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Qin, Rosie, and April Ks Salama. “Report of ipilimumab in a heart transplant patient with metastatic melanoma on tacrolimus.” Melanoma Manag 2, no. 4 (November 2015): 311–14. https://doi.org/10.2217/mmt.15.27.Full Text Link to Item
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Salama, Ahmed K. “Assessment of metals in cosmetics commonly used in Saudi Arabia.” Environ Monit Assess 188, no. 10 (October 2015): 553. https://doi.org/10.1007/s10661-016-5550-6.Full Text Link to Item
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Ribas, Antoni, Igor Puzanov, Reinhard Dummer, Dirk Schadendorf, Omid Hamid, Caroline Robert, F Stephen Hodi, et al. “Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial.” Lancet Oncol 16, no. 8 (August 2015): 908–18. https://doi.org/10.1016/S1470-2045(15)00083-2.Full Text Link to Item
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Postow, Michael A., Jason Chesney, Anna C. Pavlick, Caroline Robert, Kenneth Grossmann, David McDermott, Gerald P. Linette, et al. “Nivolumab and ipilimumab versus ipilimumab in untreated melanoma.” N Engl J Med 372, no. 21 (May 21, 2015): 2006–17. https://doi.org/10.1056/NEJMoa1414428.Full Text Link to Item
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Dummer, R., A. Daud, I. Puzanov, O. Hamid, D. Schadendorf, C. Robert, J. Schachter, et al. “A randomized controlled comparison of pembrolizumab and chemotherapy in patients with ipilimumab-refractory melanoma (Accepted).” Journal of Translational Medicine, January 15, 2015, 1–2. https://doi.org/10.1186/1479-5876-13-S1-O5.Full Text
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Bostwick, A Doran, April K. Salama, and Brent A. Hanks. “Rapid complete response of metastatic melanoma in a patient undergoing ipilimumab immunotherapy in the setting of active ulcerative colitis.” J Immunother Cancer 3 (2015): 19. https://doi.org/10.1186/s40425-015-0064-2.Full Text Open Access Copy Link to Item
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Gangadhar, Tara C., and April Ks Salama. “Clinical applications of PD-1-based therapy: a focus on pembrolizumab (MK-3475) in the management of melanoma and other tumor types.” Onco Targets Ther 8 (2015): 929–37. https://doi.org/10.2147/OTT.S53164.Full Text Link to Item
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Jiang, Betty S., Georgia M. Beasley, Paul J. Speicher, Paul J. Mosca, Michael A. Morse, Brent Hanks, April Salama, and Douglas S. Tyler. “Immunotherapy following regional chemotherapy treatment of advanced extremity melanoma.” Ann Surg Oncol 21, no. 8 (August 2014): 2525–31. https://doi.org/10.1245/s10434-014-3671-0.Full Text Link to Item
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Coit, Daniel G., John A. Thompson, Robert Andtbacka, Christopher J. Anker, Christopher K. Bichakjian, William E. Carson, Gregory A. Daniels, et al. “Melanoma, version 4.2014.” J Natl Compr Canc Netw 12, no. 5 (May 2014): 621–29. https://doi.org/10.6004/jnccn.2014.0066.Full Text Link to Item
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Beasley, Georgia M., Paul Speicher, Ketan Sharma, Hilliard Seigler, April Salama, Paul Mosca, and Douglas S. Tyler. “Efficacy of repeat sentinel lymph node biopsy in patients who develop recurrent melanoma.” J Am Coll Surg 218, no. 4 (April 2014): 686–92. https://doi.org/10.1016/j.jamcollsurg.2013.12.025.Full Text Link to Item
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Salama, April K. S., and Kevin B. Kim. “MEK inhibition in the treatment of advanced melanoma.” Curr Oncol Rep 15, no. 5 (October 2013): 473–82. https://doi.org/10.1007/s11912-013-0336-2.Full Text Link to Item
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Salama, April K. S., and Keith T. Flaherty. “BRAF in melanoma: current strategies and future directions.” Clin Cancer Res 19, no. 16 (August 15, 2013): 4326–34. https://doi.org/10.1158/1078-0432.CCR-13-0779.Full Text Link to Item
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Salama, April K. S., and Kevin B. Kim. “Trametinib (GSK1120212) in the treatment of melanoma.” Expert Opin Pharmacother 14, no. 5 (April 2013): 619–27. https://doi.org/10.1517/14656566.2013.770475.Full Text Link to Item
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Shetty, Gina, Georgia M. Beasley, Sara Sparks, Michael Barfield, Melanie Masoud, Paul J. Mosca, Scott K. Pruitt, et al. “Plasma cytokine analysis in patients with advanced extremity melanoma undergoing isolated limb infusion.” Ann Surg Oncol 20, no. 4 (April 2013): 1128–35. https://doi.org/10.1245/s10434-012-2785-5.Full Text Link to Item
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Salama, April K. S. “Evolving pharmacotherapies for the treatment of metastatic melanoma.” Clin Med Insights Oncol 7 (2013): 137–49. https://doi.org/10.4137/CMO.S9565.Full Text Link to Item
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Salama, April K. S., Nicole de Rosa, Randall P. Scheri, Scott K. Pruitt, James E. Herndon, Jennifer Marcello, Douglas S. Tyler, and Amy P. Abernethy. “Hazard-rate analysis and patterns of recurrence in early stage melanoma: moving towards a rationally designed surveillance strategy.” Plos One 8, no. 3 (2013): e57665. https://doi.org/10.1371/journal.pone.0057665.Full Text Open Access Copy Link to Item
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Gajewski, Thomas F., April K. S. Salama, Donna Niedzwiecki, Jeffrey Johnson, Gerald Linette, Cynthia Bucher, Michelle A. Blaskovich, Said M. Sebti, Frank Haluska, and Frank Cancer and Leukemia Group B. “Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104).” J Transl Med 10 (December 10, 2012): 246. https://doi.org/10.1186/1479-5876-10-246.Full Text Link to Item
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Salama, April K. S., Nicole de Rosa, Randall P. Scheri, James E. Herndon, Douglas S. Tyler, Jennifer Marcello, Scott K. Pruitt, and Amy P. Abernethy. “The effect of metastatic site and decade of diagnosis on the individual burden of metastatic melanoma: contemporary estimates of average years of life lost.” Cancer Invest 30, no. 9 (November 2012): 637–41. https://doi.org/10.3109/07357907.2012.726387.Full Text Link to Item
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Beasley, Georgia M., Colin Parsons, Gloria Broadwater, M Angelica Selim, Suroosh Marzban, Amy P. Abernethy, April K. S. Salama, et al. “A multicenter prospective evaluation of the clinical utility of F-18 FDG-PET/CT in patients with AJCC stage IIIB or IIIC extremity melanoma.” Ann Surg 256, no. 2 (August 2012): 350–56. https://doi.org/10.1097/SLA.0b013e318256d1f5.Full Text Link to Item
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Salama, April K. S., and F Stephen Hodi. “Cytotoxic T-lymphocyte-associated antigen-4.” Clin Cancer Res 17, no. 14 (July 15, 2011): 4622–28. https://doi.org/10.1158/1078-0432.CCR-10-2232.Full Text Link to Item
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Salgia, Ravi, Thomas Hensing, Nicholas Campbell, April K. Salama, Michael Maitland, Philip Hoffman, Victoria Villaflor, and Everett E. Vokes. “Personalized treatment of lung cancer.” Semin Oncol 38, no. 2 (April 2011): 274–83. https://doi.org/10.1053/j.seminoncol.2011.01.012.Full Text Link to Item
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Mollberg, N., M. Surati, C. Demchuk, R. Fathi, A. K. Salama, A. N. Husain, T. Hensing, and R. Salgia. “Mind-mapping for lung cancer: towards a personalized therapeutics approach.” Adv Ther 28, no. 3 (March 2011): 173–94. https://doi.org/10.1007/s12325-010-0103-9.Full Text Link to Item
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Surati, Mosmi, Matthew Robinson, Suvobroto Nandi, Leonardo Faoro, Carley Demchuk, Cleo E. Rolle, Rajani Kanteti, et al. “Proteomic characterization of non-small cell lung cancer in a comprehensive translational thoracic oncology database.” J Clin Bioinforma 1, no. 8 (February 28, 2011): 1–11. https://doi.org/10.1186/2043-9113-1-8.Full Text Link to Item
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El-Gendy, Kawther S., Nagat M. Aly, Eman M. Mosallam, and Ahmed K. Salama. “Preparation of antibodies and development of an enzyme immunoassay for determination of atrazine in environmental samples.” J Environ Sci Health B 46, no. 4 (2011): 321–27. https://doi.org/10.1080/03601234.2011.559885.Full Text Link to Item
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Tretiakova, Maria, April K. S. Salama, Theodore Karrison, Mark K. Ferguson, Aliya N. Husain, Everett E. Vokes, and Ravi Salgia. “MET and phosphorylated MET as potential biomarkers in lung cancer.” J Environ Pathol Toxicol Oncol 30, no. 4 (2011): 341–54. https://doi.org/10.1615/jenvironpatholtoxicoloncol.v30.i4.70.Full Text Link to Item
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Scott, April, and Ravi Salgia. “Biomarkers in lung cancer: from early detection to novel therapeutics and decision making.” Biomark Med 2, no. 6 (December 1, 2008): 577–86. https://doi.org/10.2217/17520363.2.6.577.Full Text Link to Item
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Radwan, Mohamed A., and Ahmed K. Salama. “Market basket survey for some heavy metals in Egyptian fruits and vegetables.” Food Chem Toxicol 44, no. 8 (August 2006): 1273–78. https://doi.org/10.1016/j.fct.2006.02.004.Full Text Link to Item
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Book Sections
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Sammons, S., M. McNamara, A. K. S. Salama, and J. Crawford. “Immune checkpoint inhibition.” In Side Effects of Medical Cancer Therapy: Prevention and Treatment: Second Edition, 315–53, 2018. https://doi.org/10.1007/978-3-319-70253-7_12.Full Text
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Conference Papers
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Piulats Rodriguez, J. M., S. Piperno-Neumann, P. Rutkowski, P. Nathan, J. C. Hassel, E. Espinosa, L. de la Cruz Merino, et al. “823P A propensity score weighted comparison of tebentafusp or pembrolizumab versus combination ipilimumab and nivolumab in untreated metastatic uveal melanoma.” In Annals of Oncology, 33:S924–S924. Elsevier BV, 2022. https://doi.org/10.1016/j.annonc.2022.07.949.Full Text
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Choucair, Khalil, Abdul Rafeh Naqash, April K. S. Salama, Chul Kim, Andrew Elliott, Matthew James Oberley, Phillip Walker, et al. “Age-associated differences in transcriptional expression and tumor immune microenvironment composition among older patients with cancer.” In Journal of Clinical Oncology, Vol. 40, 2022.Link to Item
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Middleton, Mark R., Omid Hamid, Alexander Noor Shoushtari, Friedegund Elke Meier, Todd Michael Bauer, April K. S. Salama, John M. Kirkwood, et al. “Updated overall survival (OS) data from the phase 1b study of tebentafusp (tebe) as monotherapy or combination therapy with durvalumab (durva) and/or tremelimumab (treme) in metastatic cutaneous melanoma (mCM).” In Journal of Clinical Oncology, Vol. 40, 2022.Link to Item
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Vaios, E. J., R. F. Shenker, P. Hendrickson, R. D’Anna, D. Niedzwiecki, D. J. Carpenter, W. Floyd, et al. “Impact of Single and Dual Immune Checkpoint Blockade on Risk of Radiation Necrosis among Patients with Brain Metastases Treated with Stereotactic Radiosurgery.” In International Journal of Radiation Oncology Biology Physics, 114:E82–83, 2022.Link to Item
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Salama, A. K. S., V. Cheshuk, J. Siveke, A. Berrocal, S. E. Abdullah, S. Lockwood, M. L. McCully, and D. Kee. “1014P Characterization of cytokine release syndrome (CRS) following treatment with tebentafusp in previously untreated patients with metastatic uveal melanoma.” In Annals of Oncology, 32:S855–S855. Elsevier BV, 2021. https://doi.org/10.1016/j.annonc.2021.08.1398.Full Text
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Kennedy, Lucy, Amanda E. D. Van Swearingen, Jeff Sheng, Dadong Zhang, Xiaodi Qin, Eric S. Lipp, Swaminathan Kumar, et al. “An immunogenomic analysis of melanoma brain metastases (MBM) compared to extracranial metastases (ECM).” In Journal of Clinical Oncology, 39:9521–9521. American Society of Clinical Oncology (ASCO), 2021. https://doi.org/10.1200/jco.2021.39.15_suppl.9521.Full Text
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Johnson, D. B., S. M. Swetter, A. K. S. Salama, and E. Wuthrick. “Cutaneous melanoma: Management of melanoma brain metastases and molecular testing.” In Jnccn Journal of the National Comprehensive Cancer Network, 19:644–47, 2021. https://doi.org/10.6004/jnccn.2021.5021.Full Text
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Dalal, N. H., F. Chino, H. Williamson, G. Beasley, A. K. S. Salama, and M. Palta. “Mind the Gap: Gendered Publication Trends in Academic Oncology.” In International Journal of Radiation Oncology*Biology*Physics, 105:E146–E146. Elsevier BV, 2019. https://doi.org/10.1016/j.ijrobp.2019.06.2198.Full Text
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Salama, April K. S., Shuli Li, Erin Renee Macrae, Jong-In Park, Edith P. Mitchell, James A. Zwiebel, Helen X. Chen, et al. “Dabrafenib and trametinib in patients with tumors with BRAF V600E/K mutations: Results from the molecular analysis for therapy choice (MATCH) Arm H.” In Journal of Clinical Oncology, 37:3002–3002. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.15_suppl.3002.Full Text
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Owonikoko, Taofeek Kunle, Kyriakos P. Papadopoulos, Melissa Lynne Johnson, Marta Gil Martin, Victor Moreno, April K. S. Salama, Emiliano Calvo, et al. “Phase 1 study of cemiplimab, a human monoclonal anti-PD-1, in patients with unresectable locally advanced or metastatic cutaneous squamous cell carcinoma (CSCC): Final efficacy and safety data.” In Journal of Clinical Oncology, 36:9557–9557. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.15_suppl.9557.Full Text
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Ribas, Antoni, Mohammed M. Milhem, Christopher J. Hoimes, Asim Amin, Inderjit Mehmi, Christopher D. Lao, Robert Martin Conry, et al. “Phase 1b/2, open label, multicenter, study of the combination of SD-101 and pembrolizumab in patients with advanced melanoma who are naïve to anti-PD-1 therapy.” In Journal of Clinical Oncology, 36:9513–9513. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.15_suppl.9513.Full Text
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Patel, S. P., F. S. Hodi, D. Gabrilovich, M. Chin, G. Gibney, A. Goldsberry, R. Gonzalez, et al. “A phase 1b/2 study of omaveloxolone in combination with checkpoint inhibitors in patients with unresectable or metastatic melanoma.” In Annals of Oncology, 28:xi30, 2017. https://doi.org/10.1093/annonc/mdx760.Full Text
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Ott, P. A., A. C. Pavlick, D. B. Johnson, L. L. Hart, J. R. Infante, J. J. Luke, J. Lutzky, et al. “A phase 2 study of glembatumumab vedotin (GV), an antibody-drug conjugate (ADC) targeting gpNMB, in advanced melanoma.” In Annals of Oncology, 27:vi393, 2016. https://doi.org/10.1093/annonc/mdw379.42.Full Text
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Gajewski, T. F., D. Niedzwiecki, J. Johnson, G. Linette, C. Bucher, M. Blaskovich, S. Sebti, and F. Haluska. “Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma: CALGB 500104.” In Journal of Clinical Oncology, 24:456S-456S. AMER SOC CLINICAL ONCOLOGY, 2006.Link to Item
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Hanks, B. A. “A HSP-TLR-Wnt5a Paracrine Signaling Axis Drives CXCR2 Ligand Recruitment of Myeloid-derived Suppressor Cells and Represents a Novel Adaptive Resistance Mechanism to Anti-PD-1 Antibody Therapy.” In Https://Jitc.Biomedcentral.Com/Track/Pdf/10.1186/S40425 017 0288 4?Site=Jitc.Biomedcentral.Com, n.d.
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Salama, April. “Characterizing Long-Term Outcomes in Metastatic Melanoma in 2020,” n.d.
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