The influence of various patient characteristics on D-dimer concentration in critically ill patients and its role as a prognostic indicator in the intensive care unit setting.

Journal Article (Journal Article;Review)

This study examines the relationship between D-dimer concentration and patient age, gender, race, and renal function, and the role of D-dimer concentration as a predictor of in-hospital mortality, in a critically ill patient population. The results demonstrate there is a correlation between increased D-dimer concentration and renal impairment in critically ill patients, with patients in renal failure having the highest D-dimer concentrations. Peak D-dimer levels were higher among female patients than in male patients, but there was no association between peak D-dimer levels and other patient characteristics. D-dimer concentration was also not predictive of in-hospital mortality.

Full Text

Duke Authors

Cited Authors

  • Spring, JL; Winkler, A; Levy, JH

Published Date

  • September 2014

Published In

Volume / Issue

  • 34 / 3

Start / End Page

  • 675 - 686

PubMed ID

  • 25168950

Electronic International Standard Serial Number (EISSN)

  • 1557-9832

Digital Object Identifier (DOI)

  • 10.1016/j.cll.2014.06.015


  • eng

Conference Location

  • United States