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The influence of various patient characteristics on D-dimer concentration in critically ill patients and its role as a prognostic indicator in the intensive care unit setting.

Publication ,  Journal Article
Spring, JL; Winkler, A; Levy, JH
Published in: Clin Lab Med
September 2014

This study examines the relationship between D-dimer concentration and patient age, gender, race, and renal function, and the role of D-dimer concentration as a predictor of in-hospital mortality, in a critically ill patient population. The results demonstrate there is a correlation between increased D-dimer concentration and renal impairment in critically ill patients, with patients in renal failure having the highest D-dimer concentrations. Peak D-dimer levels were higher among female patients than in male patients, but there was no association between peak D-dimer levels and other patient characteristics. D-dimer concentration was also not predictive of in-hospital mortality.

Duke Scholars

Published In

Clin Lab Med

DOI

EISSN

1557-9832

Publication Date

September 2014

Volume

34

Issue

3

Start / End Page

675 / 686

Location

United States

Related Subject Headings

  • Venous Thromboembolism
  • Up-Regulation
  • Sex Characteristics
  • Risk
  • Retrospective Studies
  • Predictive Value of Tests
  • Pathology
  • Male
  • Kidney Failure, Chronic
  • Intensive Care Units
 

Citation

Journal cover image

Published In

Clin Lab Med

DOI

EISSN

1557-9832

Publication Date

September 2014

Volume

34

Issue

3

Start / End Page

675 / 686

Location

United States

Related Subject Headings

  • Venous Thromboembolism
  • Up-Regulation
  • Sex Characteristics
  • Risk
  • Retrospective Studies
  • Predictive Value of Tests
  • Pathology
  • Male
  • Kidney Failure, Chronic
  • Intensive Care Units