How can we optimize the processes of care for acute coronary syndromes to improve outcomes?

Journal Article (Journal Article;Review)

Acute coronary syndromes (ACS), either ST-elevation myocardial infarction or non-ST-elevation ACS, are still one of the most common cardiac emergencies with substantial morbidity and mortality. The availability of evidence-based treatments, such as early and intense platelet inhibition and anticoagulation, and timely reperfusion and revascularization, has substantially improved outcomes in patients with ACS. The implementation of streamlined processes of care for patients with ST-elevation myocardial infarction and non-ST-elevation ACS over the last decade including both appropriate tools, especially cardiac troponin, for rapid diagnosis and risk stratification and for decision support, and the widespread availability of modern antithrombotic and interventional treatments, have reduced morbidity and mortality to unprecedented low levels. These changes in the process of care require a synchronized approach, and research using a team-based strategy and effective regional networks has allowed healthcare systems to provide modern treatments for most patients with ACS. There are still areas needing improvement, such as the delivery of care to people in rural areas or with delayed time to treatment.

Full Text

Duke Authors

Cited Authors

  • Wallentin, L; Kristensen, SD; Anderson, JL; Tubaro, M; Sendon, JLL; Granger, CB; Bode, C; Huber, K; Bates, ER; Valgimigli, M; Steg, PG; Ohman, EM

Published Date

  • November 2014

Published In

Volume / Issue

  • 168 / 5

Start / End Page

  • 622 - 631

PubMed ID

  • 25440789

Electronic International Standard Serial Number (EISSN)

  • 1097-6744

Digital Object Identifier (DOI)

  • 10.1016/j.ahj.2014.07.006


  • eng

Conference Location

  • United States