Overview
My primary research interest is in conduct and methodology of large randomized clinical trials in heart disease. I have led a number of large international clinical studies in heart attacks, unstable angina, heart failure, and atrial fibrillation. I have lead clinical studies of blood thinners and coronary intervention for heart attacks, stroke prevention in atrial fibrillation, and prevention of heart attack for patients with coronary artery disease. I have been co-director of the Reperfusion of Acute MI in Carolina Emergency Departments (RACE) project that is a North Carolina state-wide program to improve reperfusion care for acute myocardial infarction. I serve as the Chairman of the American Heart Association Mission: Lifeline program to improve heart attack care nationally as well as the American College of Cardiology/American Heart Association guideline committee for heart attack care. I have also studied the effects of genetic variation on heart disease. I work with the National Institute of Health and the Federal Drug Administration on evaluation of heart disease and of new drugs. I have developed tools to predict which patients are at risk for death, heart attack, and need for hospitalization.
Current Appointments & Affiliations
Fred Cobb, M.D. Distinguished Professor of Medicine
·
2024 - Present
Medicine, Cardiology,
Medicine
Professor of Medicine
·
2007 - Present
Medicine, Cardiology,
Medicine
Professor in the School of Nursing
·
2015 - Present
School of Nursing
Member in the Duke Clinical Research Institute
·
1988 - Present
Duke Clinical Research Institute,
Institutes and Centers
Education, Training & Certifications
University of Connecticut ·
1984
M.D.