Christopher Bull Granger

Christopher Bull Granger
Professor of Medicine

Research:
My primary research interest is in conduct and methodology of large randomized clinical trials in heart disease. I have led a number of large international clinical studies in heart attacks, unstable angina, heart failure, and atrial fibrillation. I have lead clinical studies of blood thinners and coronary intervention for heart attacks, stroke prevention in atrial fibrillation, and prevention of heart attack for patients with coronary artery disease. I have been co-director of the Reperfusion of Acute MI in Carolina Emergency Departments (RACE) project that is a North Carolina state-wide program to improve reperfusion care for acute myocardial infarction. I serve as the Chairman of the American Heart Association Mission: Lifeline program to improve heart attack care nationally as well as the American College of Cardiology/American Heart Association guideline committee for heart attack care. I have also studied the effects of genetic variation on heart disease. I work with the National Institute of Health and the Federal Drug Administration on evaluation of heart disease and of new drugs. I have developed tools to predict which patients are at risk for death, heart attack, and need for hospitalization.

Current Appointments & Affiliations

Professor of Medicine, Medicine, Cardiology, Medicine 2007
Professor in the School of Nursing, School of Nursing, Duke University 2015
Member in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 1988

Contact Information

2400 Pratt Street, Durham, NC 27705
Duke Box 3409, Durham, NC 27710
grang001@mc.duke.edu (919) 668-8900

Background
Education, Training, & Certifications
- Fellow in Cardiology, Medicine, Duke University 1988 - 1990
- Chief Medical Resident, Medicine, University of Colorado at Denver 1987 - 1988
- Medical Resident, Medicine, University of Colorado at Denver 1984 - 1987
- M.D., University of Connecticut 1984
Duke Appointment History
- Associate Professor of Medicine, Medicine, Cardiology, Medicine 2000 - 2007
- Associate Professor of Medicine, Medicine, Cardiology, Medicine 1998 - 2000
- Assistant Professor of Medicine, Medicine, Cardiology, Medicine 1993 - 1998
- Associate in the Department of Medicine, Medicine, Clinical Science Departments 1990 - 1993
Recognition
In the News
- NOV 15, 2017 Duke Health News
  
  Coordinated Emergency Care Improves Survival for Patients with Heart Attacks
- AUG 28, 2017 Duke Health News
  
  Education and Monitoring Improves the Use of Stroke-Prevention Therapies
- AUG 3, 2016 Fox News, Reuters
  
  Regional coordination cuts time to heart attack treatment
- NOV 20, 2014
  
  Coordinated Emergency Response Speeds Care to Heart Attack Patients
Awards & Honors
Expertise
Subject Headings
Research
Selected Grants
- Duke Resident Physician-Scientist Program- NHLBI awarded by National Institutes of Health 2018 - 2022
- Effect of monitoring system design on response time to cardiac arrhythmias awarded by Agency for Healthcare Research and Quality 2015 - 2020
- Janssen AF Quality Improvement Research Study awarded by Janssen Pharmaceutica, Inc. 2017 - 2019
- PARADISE awarded by Novartis Pharmaceuticals Corporation 2017 - 2019
- Evaluating and Improving Cardiac Arrest Resuscitation Efforts in Hemodialysis Clinics awarded by National Institutes of Health 2017 - 2019
- Integrated Biostatistical Training for CVD Research awarded by North Carolina State University 2017 - 2019
- INFORM-AF Janssen awarded by Janssen Scientific Affairs, LLC. 2016 - 2019
- Postdoctoral Training in Cardiovascular Clinical Research awarded by National Institutes of Health 2014 - 2019
- HeartRescue awarded by University of Washington 2016 - 2018
- Regional Systems Accelerator: Implementation of the AHA Mission (TMC) awarded by The Medicines Company 2016 - 2017
- Heart Rescue Flagship Premier Partner Program "RACE CARs" awarded by Medtronic Foundation 2013 - 2017
- HeartRescue awarded by University of Washington 2016 - 2017
- Workload effects on response time to life-threatening arrhythmias awarded by Agency for Healthcare Research and Quality 2012 - 2014
- Rare Thrombotic Diseases Clinical Research Network awarded by National Institutes of Health 2004 - 2010
- GENECARD: Gene identification in Early-Onset CAD awarded by National Institutes of Health 2003 - 2009
- DCRI CERT for Cardiovascular Therapies awarded by National Institutes of Health 1999 - 2002
Publications & Artistic Works
Selected Publications
- Book Sections
  - Kuijt WJ, Williams J, Granger CB, Krucoff MW, Roe MT. Current approaches to prevention and management of reperfusion injury. In: Management of Myocardial Reperfusion Injury. 2012 Nov 1. p. 215-238. Full Text
- Conference Papers
  - Jollis JG, Al-Khalidi HR, Roettig ML, Monk L, Berger PB, Corbett C, Doerfler S, Fordyce C, Henry TD, Kochar A, O'Brien P, Shavadia J, Wilson BH, Granger CB. Regional STEMI Systems of Care: Results of the Mission: Lifeline STEMI ACCELERATOR-2 Study. 2017 Dec 12:E461-E462. Link to Item
  - Melloni C, Dunning A, Granger CB, Thomas L, Khouri MG, Garcia DA, Hylek EM, Hanna M, Wallentin L, Gersh BJ, Douglas PS, Alexander JH, Lopes RD. Efficacy and Safety of Apixaban Versus Warfarin in Patients with Atrial Fibrillation and a History of Cancer: Insights from the ARISTOTLE Trial. 2017 Dec:1440-1448.e1. Full Text
  - Luo N, Xu H, Jneid H, Fonarow GC, Lopes RD, Granger CB, Curtis AB, Russo AM, Lewis WR, Piccini JP, Mentz RJ, Al-Khatib SM. High Use of Oral Anticoagulation in Eligible Patients Discharged With Heart Failure and Atrial Fibrillation Irrespective of Ejection Fraction: Insights From the AHA Get With The Guidelines- Atrial Fibrillation Program. Scientific Sessions of the American-Heart-Association / Resuscitation Science Symposium. 2017 Nov 11 - 2017 Nov 15. Anaheim, CA.: LIPPINCOTT WILLIAMS & WILKINS; 2017 Nov 14. Link to Item
  - Guimaraes PO, Granger CB, Chiswell K, Stebbins A, Held C, Hochman JS, Krug-Gourley S, Lonn E, Lopes RL, Stewart RAH, Vinereanu D, Wallentin L, White HD, Danchin N. Women with stable coronary artery disease have better clinical outcomes than men, but this association is modified by degree of depression: insights from the STABILITY trial. Congress of the European-Society-of-Cardiology (ESC). 2017 Aug 26 - 2017 Aug 30. Barcelona, SPAIN.: OXFORD UNIV PRESS; 2017 Aug 1:188-188. Link to Item
  - Hijazi Z, Sharma A, Andersson U, Alexander JH, Al-Khatib SM, Hanna M, Held C, Hylek EM, Lopes RD, Siegbahn A, Granger CB, Wallentin L. Biomarkers Predict Cause of Death More Accurately Than Clinical Variables in Patients With Atrial Fibrillation on Oral Anticoagulation Results From the ARISTOTLE Trial. 2016 Nov 11. Link to Item
  - Kragholm K, Lu D, Chiswell K, Al-Khalidi H, Roettig ML, Roe M, Jollis J, Granger CB. Improvement in Care and Outcomes for Ambulance-Transported ST-Elevation Myocardial Infarction Patients With and Without Out-of-Hospital Cardiac Arrest: A Mission: Lifeline STEMI ACCELERATOR Study. 2016 Nov 11. Link to Item
  - Pokorney SD, Granger CB, Bloom D, Thomas KL, Al-Khatib SM, Anderson J, Heflin MT, Granger BB. Provider Rather Than Patient Misperceptions Appear to be the Most Common Barriers to Oral Anticoagulation Use for Stroke Prevention in Atrial Fibrillation. 2016 Nov 11. Link to Item
  - Pokorney SD, Granger CB, Bloom D, Thomas KL, Al-Khatib SM, Anderson J, Heflin MT, Granger BB. Provider Rather Than Patient Misperceptions Appear to be the Most Common Barriers to Oral Anticoagulation Use for Stroke Prevention in Atrial Fibrillation. 2016 Nov 11. Link to Item
  - Goodman SG, Nicolau JC, Requena G, Maguire A, Blankenberg S, Chen JY, Granger CB, Grieve R, Pocock S, Simon T, Yasuda S, Vega AM, Brieger D, Investigators TIGRISS. Longer-term oral antiplatelet use in stable post-MI patients: Insights from the TIGRIS study. 2016 Aug 1:30-30. Link to Item
  - Rao P, Alexander JH, Wojdyla D, Atar D, Hylek EM, Hanna M, Parkhomenko A, Vinereanu D, Wallentin L, Lopes RD, Gersh BJ, Granger CB. Patients with atrial fibrillation and history of falls are at high risk for bleeding but have less bleeding with apixaban than warfarin: results from the ARISTOTLE trial. 2016 Aug 1:233-234. Link to Item
  - Wolsk E, Claggett B, Køber LV, Pocock S, Yusuf S, Swedberg K, McMurray JJ, Granger CB, Pfeffer MA, Solomon SD. Extra-Cardiac Disease Burden Contributes More Than Cardiac Disease Burden to Risk of Cardiovascular Outcomes in Patient with Preserved Ejection Fraction. 2016 Aug:S65-S66. Full Text
  - Fordyce CB, Hansen CM, Kragholm K, Jollis JG, Roettig ML, Dupre ME, Becker LB, Corbett CC, Monk L, Nelson RD, Pearson DA, Tyson C, Van Diepen S, Anderson ML, McNally B, Granger CB. STATEWIDE INITIATIVES IMPROVE THE CARE AND OUTCOMES OF PATIENTS WITH OUT-OF-HOSPITAL CARDIAC ARREST AT HOME AND IN PUBLIC LOCATIONS: RESULTS FROM THE HEARTRESCUE PROJECT. 2016 Apr:806-806. Full Text
  - Alexander J, Andersson U, Lopes RD, Hijazi Z, Hohnloser SH, Ezekowitz J, Halvorsen S, Hanna M, Granger CB, Wallentin L. Stroke and bleeding outcomes with apixaban versus warfarin in patients with high creatinine, low body weight or high age receiving standard dose apixaban for stroke prevention in atrial fibrillation. 2015 Aug 1:345-345. Link to Item
  - Avezum A, Lopes RD, Schulte PJ, Lanas F, Gersh BJ, Hanna M, Pais P, Erol C, Diaz R, Bahit MC, Bartunek J, De Caterina R, Goto S, Ruzyllo W, Zhu J, Granger CB, Alexander JH. Apixaban in Comparison With Warfarin in Patients With Atrial Fibrillation and Valvular Heart Disease: Findings From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial. 2015 Aug:624-632. Full Text
  - Bahit MC, Lopes RD, Wojdyla DM, Held C, Hanna M, Vinereanu D, Goto S, Alexander JH, Wallentin L, Granger CB. Less non-major bleeding with apixaban versus warfarin among patients with atrial fibrillation: insights from the ARISTOTLE trial. 2015 Aug 1:338-339. Link to Item
  - Hansen CM, Kragholm K, Pearson DA, Tyson C, Monk L, Nelson D, Dupre ME, Jollis JG, McNally B, Granger CB. Survival improved for men but not women, despite increased bystander CPR and first resonder defibrillation for both: results form a statewide quality improvement initiative. 2015 Aug 1:195-195. Link to Item
  - Hawkins NM, Jhund PS, Pozzi A, Solomon SD, Granger CB, Yusuf S, Pfeffer MA, Swedberg K, Virani SA, McMurray JJV. Severity of renal impairment in patients with heart failure and atrial fibrillation: implications for novel oral anticoagulant dose adjustment. 2015 Aug 1:340-340. Link to Item
  - Hijazi Z, Hohnloser SH, Andersson U, Alexander JH, Granger CB, Hanna M, Lopes RD, Siegbahn A, Wallentin L. Efficacy and safety of apixaban compared with warfarin in relation to renal function over time in patients with atrial fibrillation: Insights from the ARISTOTLE trial. 2015 Aug 1:339-339. Link to Item
  - Hijazi Z, Lindback J, Ostlund O, Siegbahn A, Alexander JH, Granger CB, Held C, Stewart RAH, White HD, Wallentin L. External validation of the biomarker-based ABC-stroke risk score for atrial fibrillation. 2015 Aug 1:710-711. Link to Item
  - Rordorf R, De Ferrari GM, Wojdyla D, De Caterina R, Thomas L, Granger CB, Leonardi S, Alexander JH, Wallentin L, Lopes RD, Trial ARISTOTLE. Digoxin use is associated with higher mortality among patients with atrial fibrillation with and without heart failure: insights from the ARISTOTLE trial. 2015 Aug 1:1068-1068. Link to Item
  - Wallentin LC, Lindback J, Held C, Granger CB, Koenig W, Stewart RAH, Tarka E, De Winter RJ, White HD, Siegbahn A. Biomarker-based risk score for prediction of cardiovascular events in stable coronary heart disease - Experiences from the STABILITY biomarker substudy. 2015 Aug 1:1041-1042. Link to Item
  - Durheim MT, Cyr DD, Al-Khatib SM, Thomas LE, Lopes RD, Gersh BJ, Palmer SM, Granger CB. Chronic Obstructive Pulmonary Disease Is Associated With Increased Risk Of Mortality Among Patients With Atrial Fibrillation: Insights From The Aristotle Trial. 2015. Link to Item
  - Sherwood MW, Al-Khalidi HR, Jollis JG, Roettig ML, Berger PB, Corbett CC, Dauerman HL, Fox K, Garvey JL, Henry TD, Rokos IC, Wilson BH, Granger CB. Developing Regional STEMI Systems of Care: Final Results of the Mission: Lifeline STEMI ACCELERATOR Study. Scientific Sessions of the American-Heart-Association and American-Stroke-Association / Resuscitation Science Symposium. 2014 Nov 15 - 2014 Nov 19. Chicago, IL. LIPPINCOTT WILLIAMS & WILKINS; 2014 Dec 2:2111-2111. Link to Item
  - Cowper PA, Sheng S, Anstrom KJ, Stafford JA, Lopes RD, Davidson-Ray L, Wallentin L, Phatak HM, Ansell J, Dorian P, Husted S, McMurray JJ, Steg PG, Alexander JH, Granger CB, Mark DB. The Cost-Effectiveness of Apixaban versus Warfarin in Patients With Atrial Fibrillation: Insights From the ARISTOTLE Study Group. 2014 Nov 25. Link to Item
  - Hansen CM, Jollis JG, Dupre M, McNally B, Monk L, Tyson C, Pearson DA, Nelson RD, Myers B, Granger CB. Improved Rates of Bystander and First Responder Intervention Are Associated with Improved Survival After Out-of-Hospital Cardiac Arrest Following Statewide Quality Improvement Initiative. 2014 Nov 25. Link to Item
  - Hansen CM, Jollis JG, Dupre M, McNally B, Monk L, Tyson C, Pearson DA, Nelson RD, Myers B, Granger CB. Early Defibrillation, Mainly by Bystanders and First Responders, Associated with Higher Survival in Statewide Data. 2014 Nov 25. Link to Item
  - Hijazi Z, Siegbahn A, Andersson U, Lindahl B, Granger CB, Alexander JH, Atar D, Gersh BJ, Hanna M, Harjola V-P, Horowitz JD, Husted S, Hylek EM, Lopes RD, McMurray JJ, Wallentin L. Does Repeat Measurement of High Sensitivity Troponin I Improve Prediction of Cardiovascular Events in Atrial Fibrillation?. 2014 Nov 25. Link to Item
  - Rao MP, Dupre M, Hansen C, Milford-Beland S, Monk L, Tyson C, Pearson DA, Nelson RD, Meyers B, Jollis JG, Granger CB. Pre-Hospital Initiation of Therapeutic Hypothermia Associated With Better Survival and Neurologic Outcome in a Broad Population of Patients in North Carolina. 2014 Nov 25. Link to Item
  - Wallentin L, Hijazi Z, Andersson U, Lindahl B, Granger CB, Alexander JH, Atar D, Gersh BJ, Hanna M, Harjola V-P, Horowitz JD, Husted S, Hylek EM, Lopes RD, McMurray JJ, Siegbahn A. Single Measurement of GDF-15 Provides Reliable Prognostication of Stroke and Major Bleeding in Atrial Fibrillation. 2014 Nov 25. Link to Item
  - Asberg S, Hijazi Z, Siegbahn A, Andersson U, Granger CB, Hanna M, Horowitz JD, Lopes RD, Lindahl B, Wallentin L, Investigators ARISTOTLE. Galectin-3 is associated with worse clinical outcome in patients with atrial fibrillation: A substudy from the ARISTOTLE trial. 2014 Sep 1:426-426. Link to Item
  - Christersson C, Wallentin L, Andersson U, Hylek EM, Husted S, De Caterina R, Hanna M, Lopes RD, Granger CB, Siegbahn A. The efficacy of apixaban compared to warfarin in patients with atrial fibrillation with high coagulation activity despite anticoagulant treatment. 2014 Sep 1:866-867. Link to Item
  - Hijazi Z, Lindback J, Siegbahn A, Alexander JH, Held C, Hanna M, Lopes RD, Oldgren J, Granger CB, Wallentin L, Investigators ARISTOTLE. A new biomarker based risk score for predicting major bleeding in atrial fibrillation - the ABC (age, biomarkers, current disease) risk score. 2014 Sep 1:357-357. Link to Item
  - Hijazi Z, Wallentin L, Siegbahn A, Andersson U, Alexander JH, Atar D, Gersh BJ, Hanna M, Harjola VP, Horowitz JD, Husted S, Hylek EM, Lopes RD, McMurray JJV, Granger CB, ARISTOTLE Investigators . High-sensitivity troponin T and risk stratification in patients with atrial fibrillation during treatment with apixaban or warfarin. 2014 Jan:52-61. Full Text
  - Bagai A, Wang Y, Wang TY, Curtis J, Gurm HS, Peterson ED, Saucedo JF, Granger CB, Roe MT, Bhatt DL, McNamara RL, Alexander KP. In-Hospital ADP Receptor Inhibitor Switching in Myocardial Infarction Patients Treated With Percutaneous Coronary Intervention: Insights From the National Cardiovascular Data Registry (R). 2013 Nov 26. Link to Item
  - Granger CB, Bates ER, Jollis JG, Antman E, Nichol G, O'Connor RE, Bjerke C, Gregory T, Peng SA, Ellrodt G, Henry TD, French WJ, Jacobs A. Improving Care of ST Segment Elevation Myocardial Infarction in the United States 2008 to 2012: A Report From Mission: Lifeline. 2013 Nov 26. Link to Item
  - Hijazi Z, Siegbahn A, Andersson U, Granger CB, Alexander JH, Atar D, Gersh BI, Hanna M, Harjola V-P, Horowitz JD, Husted S, Hylek EM, Lopes RD, McMurray JJ, Wallentin L. Combining High Sensitivity Troponin I and T Measurements Improves Prediction of Long-Term Clinical Outcomes in Patients With Atrial Fibrillation - An Aristotle Substudy. 2013 Nov 26. Link to Item
  - Vinereanu D, Stevens SR, Alexander JH, Al-Khatib SM, Avezum A, Bahit C, Granger CB, Lopes RD, Halvorsen S, Hanna M, Husted S, Hylek EM, Margulescu AD, Wallentin L, Atar D. Efficacy and Safety of Apixaban in Patients With Atrial Fibrillation According to Sex: Results From the ARISTOTLE Trial. 2013 Nov 26. Link to Item
  - Held C, Hylek EB, Alexander JH, Hanna M, Lopes RD, Wojdyla D, Granger CB, Wallentin L. Risk of events in the 30 days following a major bleed with Apixaban or Warfarin - experiences from the ARISTOTLE trial. 2013 Aug:99-99. Link to Item
  - Horowitz JD, De Caterina R, Heresztyn T, Andersson U, Lopes R, Hylek E, Mohan P, Hanna M, Granger CB, Wallentin L, Investigators ARISTOTLE. ADMA and SDMA predict outcomes in patients with chronic atrial fibrillation: an ARISTOTLE substudy. 2013 Aug:1040-1041. Link to Item
  - Lopes RD, Garcia DA, Wojdyla D, Dorian P, Alexander JH, Wallentin L, Lanas F, Hanna M, Held C, Granger CB, Investigators ARISTOTLE. Use of apixaban and warfarin in patients undergoing invasive procedures: insights from ARISTOTLE. 2013 Aug:98-99. Link to Item
  - Newby LK, Sarov-Blat L, Melloni C, Patel MR, Heitner JF, Hamm CW, Aylward P, Tanguay J-F, De Winter RJ, Marber MS, Lepore JJ, Lerman A, Hasselblad V, Al-Khalidi H, Sprecher DL, Granger CB. Safety and Efficacy of Losmapimod in Non-ST-Segment Elevation Acute Myocardial Infarction: Results of the SOLSTICE Phase 2 Randomized Trial. 2012 Dec 4:2787-2788. Link to Item
  - Christersson C, Schollin M, Alexander JH, Bersh BJ, Horowitz J, Hylek EM, Mohan P, Granger CB, Wallentin L, Siegbahn A. Increased levels of D-dimer in atrial fibrillation identify patients with higher risk of thromboembolic events and death. 2012 Aug:969-969. Link to Item
  - Granger CB, Alexander JH, Hanna M, Wang J, Mohan P, Lawrence J, Hylek E, Ansell JE, Wallentin L, Comm ARISTOTLEI. Events after discontinuation of randomized treatment at the end of the ARISTOTLE trial. 2012 Aug:685-686. Link to Item
  - Gupta DK, Castagno D, Granger CB, Yusuf S, Swedberg K, McMurray JJV, Pfeffer MA, Solomon SD. Prognostic Impact of an Ischemic Etiology of Chronic Heart Failure across the Spectrum of Ejection Fractions in the CHARM Program. 2012 Aug:S78-S78. Full Text Link to Item
  - McMurray JJV, Connolly SJ, Hart R, Flaker G, Lopes RD, Wang J, Hanna M, Alexander JH, Granger CB, Wallentin L, Investigators ARISTOTLE. Effect of apixaban on all-cause mortality in atrial fibrillation: an imputed placebo analysis. 2012 Aug:52-52. Link to Item
  - McMurray JJV, Lewis B, Ezekowitz J, Gersh B, Lopes RD, Wojdyla D, Mohan P, Wallentin L, Alexander JH, Granger CB, Investigators ARISTOTLE. Risk of stroke, systemic embolism or death according to heart failure and left ventricular function status in patients with atrial fibrillation: results of the ARISTOTLE trial. 2012 Aug:519-519. Link to Item
  - Siegbahn A, Christersson C, Schollin M, Alexander JH, Horowitz J, Hylek EM, Lopes RD, Mohan P, Granger CB, Wallentin L. Increased levels of D-dimer identify patients with atrial fibrillation at high risk for bleeding an ARISTOTLE substudy. 2012 Aug:51-51. Link to Item
  - Wallentin LC, Christersson C, Siegbahn A, Schollin M, Alexander JH, Hanna M, Hylek EM, Horowitz J, McMurray JJV, Granger CB. NT-proBNP for risk stratification in atrial fibrillation during treatment with apixaban or warfarin. 2012 Aug:51-51. Link to Item
  - Brunner MP, Shah SH, Craig DM, Bain JR, Muehlbauer MJ, Newgard CB, Kraus WE, Granger CB, Sketch MH, Newby LK. EFFECT OF HEPARIN ADMINISTRATION ON METABOLOMIC PROFILES FROM SAMPLES OBTAINED DURING CARDIAC CATHETERIZATION. 2011 Apr 5:E1147-E1147. Full Text Link to Item
  - Truffa AA, Lopes RD, White KR, Mehta RH, Patel MR, Pieper KS, Armstrong PW, Granger CB. SERIOUS INFECTIONS IN PATIENTS WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION TREATED WITH PRIMARY PCI ARE RARE, BUT ASSOCIATED WITH HIGHER MORTALITY. 2011 Apr 5:E980-E980. Full Text Link to Item
  - Granger CB, Monk LM, Roettig ML, Al-Khalidi HR, Applegate RJ, Corbett CC, Garvey JL, Hathawy WR, Wilson BH, Jollis JG. State-Wide Care is Improved in the Reperfusion of Acute MI in Carolina Emergency Department Emergency Response (RACE-ER) Systems Improvement Program. 2010 Nov 23:2223-2224. Link to Item
  - Ezekowitz J, Armstrong PW, Granger CB, Theroux P, Stebbins A, Patel MR. Early Prediction of Left Ventricular Ejection Fraction 90 Days After STEMI Using NT-proBNP and Cardiac Magnetic Resonance Imaging. 2009 Nov 3:S826-S826. Link to Item
  - Glaser R, Kaul P, Roberts R, Armstrong PW, Granger CB, Barden LG, Hochman J, White H, Mahaffey KW. Women With ST Elevation Myocardial Infarction Treated With Primary PCI Have Worse Outcomes Than Men in the Modern Era: Results From the APEX-AMI Trial. 2009 Nov 3:S936-S936. Link to Item
  - Glickman S, Cairns CB, Chen AY, Granger CB, Cannon CP, Fraulo ES, Peterson ED, Roe MT. Delays in Fibrinolytic Administration for Acute ST-Segment Elevation Myocardial Infarction: Results From the National Cardiovascular Data Registry (ACTION-GWTG). 2009 Nov 3:S423-S423. Link to Item
  - Katz JN, Echols MR, Wyman A, Gore JM, Peacock WF, Anderson FA, Granger CB, Peterson E, Investigators STAT. African Americans Hospitalized With Acute, Severe Hypertension Receive Less Intense Treatment and Follow-up Than Peers: Results From the STAT Registry. 2009 Nov 3:S421-S421. Link to Item
  - Mehta RH, Lopes RD, Stebbins A, Rao SV, Pieper KS, Califf RM, Alexander JH, Granger CB. Differences in Bleeding Rates Accounts for All of the Excess Mortality in African Americans Compared With Caucasians With ST-Elevation Myocardial Infarction treated With Fibrinolysis. 2009 Nov 3:S522-S523. Link to Item
  - Newby LK, Shah SH, Sun J-L, Pieper K, Hauser ER, Kraus WE, Granger CB. Red Cell Distribution Width (RDW) is a Strong Predictor of Outcome and is Weakly Associated With Clinical Variables in Patients at Risk for Cardiovascular Events. 2009 Nov 3:S1174-S1174. Link to Item
  - Piccini JP, Schulte PJ, Pieper KS, Mehta RH, Topol EJ, White HD, Van de Werf F, Ardissino D, Califf RM, Granger CB, Ohman EM, Nexander JH. Antiarrhythmic Drug Therapy for Sustained Ventricular Arrhythmias Complicating Acute Myocardial Infarction. 2009 Nov 3:S632-S633. Link to Item
  - Shah SH, Sun J-L, Pieper K, Crosslin DR, Haynes C, Bain JR, Muehlbauer M, Stevens RD, Hauser ER, Kraus WE, Newgard CB, Granger CB, Califf RM, Newby LK. Plasma Metabolomic Profiles Predict Future Cardiovascular Events. 2009 Nov 3:S466-S467. Link to Item
  - Berger JS, Gallup D, Roe M, Armstrong PW, Simes RJ, White HD, Van de Wert F, Topol EJ, Granger CB, Harington RA, Califf RM, Becker RC, Douglas PS. Sex-based differences in mortality following acute coronary syndromes. 2008 Mar 11:A194-A194. Link to Item
  - Berger JS, Gallup D, Roe M, Granger CB, Armstrong PW, Simes RJ, White HD, Van de Wed F, Topol EJ, Harrington RA, Califf RM, Becker RC, Douglas PS. Sex differences in clinical presentation and angiographic data in acute coronary syndromes. 2008 Mar 11:B55-B56. Link to Item
  - Kim JH-J, Newby LK, Clare R, Shaw LK, Lodge A, Smith P, Jolicceur ME, Mark DB, Granger CB. Clopidogrel and CABG-related bleeding: Not as important as currently believed?. 2008 Mar 11:A223-A224. Link to Item
  - Lopes RD, White HD, Hochman J, Horton JR, Van de Werf F, Ardissino D, Nielsen TT, Weaver WD, Widimsky P, Armstrong PW, Granger CB. New onset atrial fibrillation following myocardial infarction is a strong independent predictor of mortality in patients treated with primary percutaneous coronary intervention. 2008 Mar 11:A11-A12. Link to Item
  - Lopez-Sendon J, Gurfinkel EP, de Sa EL, Agnelli G, Gore JM, Steg PG, FitzGerald G, Granger CB, Investigators GRACE. Factors related to heart rupture in acute coronary syndromes. The global registry of acute coronary events. 2008 Mar 11:A245-A246. Link to Item
  - Therou P, Armstrong PW, Moliterno DJ, Neumann F-J, Stebbins AL, Mahaffey KW, Hochman JS, Hamm CW, Granger CB, Investigators APEXAMI. Do selected markers of inflammatory response during the acute phase of ST-segment elevation myocardial infarction relate to outcome?. 2008 Mar 11:A185-A185. Link to Item
  - Wang TY, Honeycutt EF, Ohman EM, Moll S, Granger CB, Tapson VF. Incidence and management of acquired thrombocytopenia among patients receiving prolonged heparin venous thromboembolism prophylaxis: Insights from the complications after thrombocytopenia caused by heparin (CATCH) registry. 2008 Mar 11:A310-A310. Link to Item
  - Granger CB, Babb JD, Bohle DJ, Fletcher SM, Garvey JL, Hathaway WR, Hoekstra JW, Roettig ML, Wilson BH, Jollis JG. The Reperfusion of Acute MI in Carolina Emergency Departments (RACE) systems improvement program: Primary results. 2007 Nov 27:2629-2629. Link to Item
  - Huber K, Aylward PE, Van'T Hof AW, Montalescot G, Jr HDR, Betriu GA, Widimsky P, Westerhout CM, Granger CB, Armstrong PW. Glycoprotein IIb/IIIa inhibitors before primary percutaneous coronary intervention of ST-elevation myocardial infarction improve perfusion and outcomes: Insights from APEX-AMI. 2007 Oct 16:673-673. Link to Item
  - Martel C, Theroux P, Labarthe B, Rivard J, Bonnefoy A, Granger CB, Armstrong PW. The serum of pexelizumab-treated ST-Segment elevation MI patients reduces complement activation but not cell apoptosis. 2007 Oct 16:723-723. Link to Item
  - Allen LA, Felker GM, Pocock SJ, McMurray JJV, Pfeffer MA, Swedberg K, Wang D, Yusuf S, Michelson EL, Granger CB. Liver function test abnormalities and outcome in patients with chronic heart failure: Data from the candesartan in heart failure assessment of reduction in mortality and morbidity (CHARM) program. 2007 Mar 6:44A-44A. Link to Item
  - Allen LA, Felker GM, Pocock SJ, Shaw LK, McMurray JJV, Pfeffer MA, Swedberg K, Yusuf S, Michelson EL, Granger CB. Red cell distribution width as a novel prognostic marker in heart failure: Data from the CHARM program and the duke databank. 2007 Mar 6:88A-88A. Link to Item
  - Berger JS, Stebbins A, Granger CB, Armstrong PW, Van de Werf F, White HD, Simes RJ, Pieper K, Harrington RA, Califf RM, Peterson ED. Initial aspirin dose for the treatment of ST elevation myocardial infarction. 2007 Mar 6:202A-202A. Link to Item
  - Frazier CG, Shah S, Nelson CL, Seo D, Hauser ER, Crosslin D, Gregory S, Goldschmidt-Clermont PJ, Granger CB, Newby LK. Variants in genes associated with inflammation and vascular cell function are associated with vulnerable plaque. 2007 Mar 6:199A-199A. Link to Item
  - Hudson MP, Granger CB, O'Neill WW, Stebbins AL, Widimsky P, Aylward P, Ruzyllo W, Holmes D, Mahaffey KW, Armstrong PW. Faster times to primary percutaneous coronary intervention are associated with better survival: Insights from the APEX-AMI (Assessment of Pexelizumab in Acute Myocardial Infraction) trial. 2007 Mar 6:42B-43B. Link to Item
  - Jolicoeur ME, Ohman ME, Honeycutt EF, Mazon FJN, Beckerd RC, Crespo EM, Oliveira GBF, Moliterno DJ, Anstrom KJ, Granger CB. Bleeding is common among patients treated with heparin experiencing thrombocyllopenia and confers a high mortality risk: Report from the CATCH registry. 2007 Mar 6:340A-340A. Link to Item
  - O'Neill WW, Armstrong PW, Alkhalidi HR, Hamm CW, Jr HDR, Todaro TG, Adams PX, de Werf FJV, Granger CB, Investigators APEX. Blood transfusion is independently associated with death in acute myocardial infarction: Insights from APEX-AMI (Assessment of Pexelizumab in Acute Myocardial Infarction) trial. 2007 Mar 6:36B-36B. Link to Item
  - Rao SV, Kaul P, Liao L, Mark DB, Eisenstein EL, Armstrong PW, Ohman M, Granger CB, Califf RM, Harrington RA. Bleeding complications are a major driver of resource use among patients with acute coronary syndromes. 2007 Mar 6:252A-252A. Link to Item
  - Roe MT, Grimes K, Bates E, Kleiman N, Bode C, Huber K, Granger CB, Costa M, Gibson CM, Solomon SD, Widimsky P, Sadowski Z, Mochly-Rosen D, Harrington RA. Inhibition of 8 delta-protein kinase C to ameliorate reperfusion injury during primary percutaneous coronary intervention for acute ST-elevation myocardial infarction - Preliminary results from the DELTA MI trial. 2007 Mar 6:215A-215A. Link to Item
  - Shah SH, Hauser ER, Nelson C, Gregory S, Crosslin D, Haynes C, Johnson J, Seo D, Kraus WE, Granger CB, Goldschmidt-Clermont P, Newby LK. ALOX5AP genetic variants are associated with in-stent restenosis after percutaneous coronary intervention. 2007 Mar 6:211A-211A. Link to Item
  - Shah SH, Nelson C, Stafford JA, Granger CB, Kraus WE, Hauser ER. Clinical predictors of presence of left main coronary artery disease on angiography in a large cohort. 2007 Mar 6:218A-218A. Link to Item
  - Widimsky P, Weaver WD, Van de Werf F, Neumann F-J, Ardissino D, Stebbins A, van t'Hof A, Nielsen TT, Armstrong PW, Granger CB, investigators APEX. Patients transferred for primary PCI in APEX-AMI (Assessment of pexelizumab in acute myocardial infarction) trial have only modest symptom onset to PCI delays and good outcomes. 2007 Mar 6:241A-241A. Link to Item
  - Armstrong PW, Adams PX, Hamm CW, O'Neill WW, Vahanian AS, Granger CB, Holmes DR, Todaro TG, Van de Werf F. Assessment of pexelizumab in acute myocardial infarction (APEX AMI): A multicenter, randomized, double-blind, parallel-group, placebo-controlled study of pexelizumab in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention. 2006 Nov 28:2425-2425. Link to Item
  - Chang SM, Kosolcharoen P, Murray D, Pfeffer MA, Yusuf S, Swedberg K, McMurray J, Granger CB, Michelson EL, Olofsson B, Johansson PA, Dunlap ME. Lack of interaction between angiotensin receptor blocker and aspirin in patients with heart failure. 2006 Oct 31:767-767. Link to Item
  - Wallentin LC, Mehta SR, Afzal R, Chrolavicius S, Granger CB, Budaj A, Peters RJ, Bassand J-P, Fox KA, Yusuf S, Investigators O. Effects of fondaparinux in patients with ST-Segment elevation acute myocardial infarction non-eligible for reperfusion treatment. 2006 Oct 31:699-700. Link to Item
  - Wang L, Hauser ER, Shah SH, Haynes C, Rose JM, Harris M, Rombaut J, Nelson S, Hale AB, Crosslin D, Gregory SG, Granger CB, Haines JL, Jones CJ, Crossman DC, Kraus WE, Pericak-Vance MA, Goldschmidt-Clermont PJ, Vance JM. Identification of kalirin gene as a novel coronary artery disease gene through peak-wide association mapping on chromosome 3q13-21. 2006 Oct 31:887-887. Link to Item
  - Goldstein P, Wiel E, van de Werf F, Steg G, Armstrong P, Ross AM, Bogoerts K, Granger CB, Vahanian A, Danchin N, Puel J, ASSENT-4PCI FI. ASSENT-4 in "French" perspective. Outcomes of STEMI patients treated with pre-hospital thrombolysis in mobile intensive care units in France across trials and registries. 2006 Oct 22:80M-80M. Link to Item
  - Granger CB, Wallentin L, Avezum A, Mehta S, Diaz R, Ruda M, Afzal R, Yusuf S, OASIS 5. Fondaparinux results in less bleeding than enoxaparin, irrespective of heparin use, for patients with acute coronary syndromes. 2006 Aug:448-448. Link to Item
  - Granger CB, Wang D, Pfeffer MA, Swedberg K, Cleland JG, Poole-Wilson P, Charlesworth A, Pocock S, CHARM . A practical, validated model for prediction of risk in chronic heart failure. 2006 Aug:173-173. Link to Item
  - Oliveira G, Granger CB, Van De Werf F, Montalescot G, Fox KAA, Gulba D, Allegrone J, Avezum A, Investigators GRACE. Patients with acute ST-elevation myocardial infarction and prehospital delay to presentation > 12 hours: high risk of worse outcomes and selective use of reperfusion therapies. The GRACE registry. 2006 Aug:912-912. Link to Item
  - Weir RAP, Mcmurray JJV, Granger CB, Puu M, Ostergren J, Yusuf S, Swedberg K, Pfeffer MA, investigators C-AT. Use of triple and quadruple neurohormonal blockade in heart failure: new data from the candesartan in heart failure assessment of reduction in mortality and morbidity (CHARM)-Added trial. 2006 Aug:331-331. Link to Item
  - Al-Khatib S, Shaw L, Velazquez EJ, White H, Granger CB, Pfeffer MA, McMurray JJV, Califf RM. Rhythm versus rate control for atrial fibrillation in post-Ml patients with heart failure: Results from the VALIANT trial. 2006 Feb 21:41A-41A. Link to Item
  - Mehta RH, Greenbaum AB, Lokhnygina Y, Newby LK, de Wert FV, Armstrong PW, Pieper KS, Califf RM, Granger CB, Harrington RA. Incidence and not timing of death or myocardial infarction differ according to risk in patients with non-ST elevation acute coronary syndromes: Implications for long-term treatment and follow-up. 2006 Feb 21:207A-207A. Link to Item
  - Mehta RH, Harrington RA, Yang QH, Pieper KS, Califf RM, Granger CB. Initial heart rate and systolic blood pressure provides important insights in the risk-stratification of agerelated mortality among patients presenting with cardiogenic shock and acute ST-elevation myocardial infarction treated with fibrinolysis. 2006 Feb 21:177A-177A. Link to Item
  - Oliveira GB, Anstrom KJ, Honeycutt EF, Abrams CS, Becker RC, Berger PB, Moliterno DJ, Moll S, Rice L, Kleiman N, Rodgers JE, Steinhubl SR, Tapson VF, Ohman EM, Granger CB. Prolonged heparin exposure, development of thrombocytopenia, use of GP IIb/IIIa inhibitors, and history of renal dysfunction predict moderate or severe bleeding: A report from the complications after thrombocytopenia caused by heparin (CATCH) registry. 2006 Feb 21:251A-251A. Link to Item
  - Eagle KA, Mehta RH, Nallamothu BK, Granger CB, Steg PG, Van de Werf F, Lopez-Sendon J, Goodman SG, Allegrone J, Fox KA, Investigators GRACE. Global reperfusion therapy in acute myocardial infarction - 1999 to 2004: We're getting better, but we have a long way to go. The Global Registry of Acute Coronary Events. 2005 Oct 25:U860-U861. Link to Item
  - Goyal A, Mahaffey KW, Gang J, Pieper K, Nicolau JC, Armstrong PW, Hochman JS, Weaver WD, Ruzyllo W, Peterson JL, Theroux P, Todaro TG, Mojcik CF, Granger CB, Investigators CARDINAL. Drop in glucose level following acute myocardial intarction predicts improved survival in nondiabetic patients, regardless of baseline glucose level. 2005 Oct 25:U846-U846. Link to Item
  - Kenchaiah S, McMurray JJ, Pocock SJ, Wang DL, Solomon SD, McEntegart M, Michelson EL, Granger CB, Pfeffer MA. Weight loss (but not weight gain) is a strong predictor of mortality in chronic heart failure: Findings from the candesartan in heart failure assessment of reduction in mortality and morbidity (CHARM) program. 2005 Oct 25:U660-U660. Link to Item
  - Mehta RH, Califf RM, Garg J, Pieper KS, Granger CB. The impact of body anthropomorphic indices on clinical outcomes in patients with acute ST elevation myocardial infarction. 2005 Oct 25:U918-U918. Link to Item
  - Mehta RH, Van De Werf F, Avezum A, Agnelli G, Eagle KA, Goldberg RJ, Dabbous O, Granger CB. Despite geographical heterogeneity in baseline use, guideline-directed treatments for acute coronary syndromes improve in all regions from 1999 to 2003. The Global Registry of Acute Coronary Events. 2005 Oct 25:U860-U860. Link to Item
  - Nallamothu BK, Fox KA, Kennelly BM, Van de Werf F, Gore JM, Granger CB, Dabbous OH, Kline-Rogers E, Eagle KA, Investigators GRACE. Is the relationship of time delay in reperfusion and mortality steeper for fibrinolysis than for primary percutaneous coronary intervention? The global registry of acute coronary events. 2005 Oct 25:U859-U859. Link to Item
  - Rao SV, Banerjee A, Pieper K, Granger CB, Newby K, van de Werf F, White HD, Califf RM, Harrington RA. Bleeding and blood transfusion rates are higher among acute coronary syndrome patients in the United States than in other countries. 2005 Oct 25:U632-U633. Link to Item
  - Shah SH, Wang LY, Rose J, Crossman DC, Granger CB, Haines JL, Jones CJ, Mooser V, Haynes C, Pedersen B, Goldschmidt-Clermont P, Vance J, Hauser ER, Kraus WE. Neuropeptide Y gene variants are linked to and associated with premature coronary artery disease in two independent datasets. 2005 Oct 25:U850-U850. Link to Item
  - Westerhout C, Chang WC, Fu YL, Goodman SG, van de Werf F, Granger CB, Armstrong PW. Are STEMI outcomes after fibrinolysis worse during "Off hours"? Insights on circadian rhythm from ASSENT-2. 2005 Oct 25:U376-U376. Link to Item
  - Brieger D, Dabbous O, Eagle KA, Budaj A, Avezum A, Granger CB, Costa B, Steg PG, Investigators GRACE. Deriving a safety index from the GRACE risk score. 2005 Sep:566-566. Link to Item
  - Goldberg RJ, Spencer FA, Lopez-Sendon J, Van de Werf F, Montalescot G, Anderson FA, Malone S, Granger CB, Investigators GRACE. International and time trends in the use and characteristics of patients with acute coronary syndromes treated with clopidogrel: the global registry of acute coronary events experience. 2005 Sep:160-160. Link to Item
  - Granger B, Swedberg K, Ekman I, Ostergren J, Yusuf S, Michelson L, Granger CB, Pfeffer M. Women (especially younger women) with chronic heart failure are less adherent to medication: results from the CHARM program. 2005 Sep:185-185. Link to Item
  - Hawkins NM, Wang D, McMurray JJV, Pfeffer MA, Swedberg K, Granger CB, Yusuf S, Dunn FG, Committees CHARMIA. Bundle branch block is associated with worse clinical outcomes in heart failure, especially with reduced systolic function: evidence from the CHARM programme. 2005 Sep:381-381. Link to Item
  - Lewis E, McMurray JJV, Granger CB, Michelson E, Carlsson J, Yusuf S, Swedberg K, Pfeffer MA, Comm CHARMI. Predictors of quality of life in symptomatic heart failure patients across the left ventricular ejection fraction spectrum. 2005 Sep:600-600. Link to Item
  - Mcentegart M, Yusuf S, Pfeffer MA, Michelson EL, Ostergren J, Granger CB, Swedberg K, McMurray JJV. Factors precipitating heart failure hospitalisation: a novel analysis of the candesartan in heart failure: assessment of reduction in mortality and morbidity (CHARM) programme. 2005 Sep:280-280. Link to Item
  - O'Meara E, Pfeffer MA, Swedberg K, Yusuf S, Michelson EL, Ostergren J, Granger CB, McMurray JJV. Female gender is an independent predictor of better outcome in chronic heart failure: results from the CHARM programme. 2005 Sep:184-184. Link to Item
  - Oliveira GBF, Anstrom KJ, Honeycutt EF, Becker RC, Moliterno DJ, Moll S, Ohman EM, Granger CB, Investigators CATCHR. Intravenous unfractionated heparin, patient profile, and the magnitude of thrombocytopenia are associated with heparin-induced thrombocytopenia (HIT) antibodies: insights from the CATCH registry. 2005 Sep:725-725. Link to Item
  - Olsson LG, Swedberg K, Granger CB, Michelson E, McMurray JJV, Puuh M, Yusuf S, Pfeffer MA. Atrial fibrillation carries similar risks in heart failure irrespective of ejection fraction-results from the Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity (CHARM). 2005 Sep:378-379. Link to Item
  - Spencer FA, Gore JM, Oliveira G, Montalescot G, Fox KAA, Goodman SG, Malone S, Granger CB, Investigators GRACE. Determinants of delay in patients undergoing primary angioplasty for ST-segment elevation myocardial infarction. The Global Registry of acute coronary events. 2005 Sep:621-621. Link to Item
  - Alghamdi S, Fu YL, Goodman SG, Chang WC, Van de Werf F, Granger CB, Armstrong PW. The baseline ECG in ST elevation myocardial infarction provides powerful prognostic insight: Observations from ASSENT. 2005 Feb 1:208A-209A. Link to Item
  - Ezekowitz JA, Theroux P, Chang WC, Mahaffey KW, Granger CB, Weaver WD, Armstrong PW. Natriuretic peptide insights in acute myocardial infarction. 2005 Feb 1:228A-228A. Link to Item
  - Ohman EM, Abrams CS, Honeycutt EF, Becker RC, Crespo EM, Anstrom KJ, Moliterno DJ, Rice L, Rodgers JE, Steinhubl SR, Granger CB. High mortality after discharge among patients with high risk for developing heparin-induced thrombocytopenia or thrombosis: 6-month follow-up results of the complications after thrombocytopenia caused by heparin (CATCH) registry. 2005 Feb 1:411A-411A. Link to Item
  - Sinnaeve PR, Donahue M, Grass P, Vonderscher J, Seo D, Goldschmidt P, Granger CB. Gene expression profile in circulating leukocytes identifies patients with coronary artery disease. 2005 Feb 1:414A-414A. Link to Item
  - Granger CB. Importance of CHARM in relation to other heart failure trials with ARBs. 2004 Dec:H55-H60. Link to Item
  - Donahue MP, Rose K, Vonderscher J, Bougueleret L, Nelson CL, Cohen D, Granger CB. Proteomic discovery of coronary artery disease proteins using industrial scale analysis of pooled plasma: Results from the pooled plasma proteomics project. 2004 Oct 26:212-212. Link to Item
  - Granger BB, Swedberg K, Ekman I, Ostergren J, Yusuf S, Michelson EL, Zeneca A, Granger CB, Pfeffer MA. Adherence, even to placebo, is strongly and independently related to outcome in patients with chronic heart failure: Results from the CHARM program. 2004 Oct 26:557-557. Link to Item
  - Mehta RH, Marks D, Sohn SH, Granger CB. African Americans have higher long-term mortality and more stroke and bleeding than caucasians following reperfusion therapy for acute myocardial infarction. 2004 Oct 26:798-798. Link to Item
  - Oliveira GB, Anstrom KJ, Honeycutt EF, Abrams CS, Becker RC, Berger PB, Moliterno DJ, Moll S, Rice L, Rodgers JE, Steinhubl SR, Tapson VF, Ohman EM, Granger CB. Days on intravenous heparin predicts thrombocytopenia and drop platelet count on heparin predicts mortality: Findings from the complications after thrombocytopenia caused by heparin (CATCH) registry. 2004 Oct 26:559-560. Link to Item
  - Oliveira GB, Avezum A, Anderson FA, Dabbous OH, Budaj A, Goldberg RJ, Brieger D, Fox KA, Granger CB. Evidence-based risk stratification is not optimally used to target proven therapies in non-ST-elevation acute coronary syndromes: The global registry of acute coronary events (GRACE). 2004 Oct 26:659-659. Link to Item
  - Pocock SJ, Wang DL, Pfeffer MA, McMurray JJ, Swedberg K, Ostergren J, Yusuf S, Michelson EL, Pieper KS, Granger CB. Predicting mortality and morbidity in chronic heart failure independent of left ventricular systolic function: Results from the CHARM program. 2004 Oct 26:752-752. Link to Item
  - Young JB, Swedberg K, Dunlap ME, Pfeffer MA, Probstfield JL, Granger CB, McKelvey RS, McMurray MJV, Michaelson EL, Olofsson B, Ostergren J, Yusuf S. Reduction in all-cause mortality and morbidity with candesartan in patients with chronic heart failure and systolic left ventricular dysfunction: Results of the CHARM low. 2004 Aug:S76-S76. Full Text Link to Item
  - Shimpi RA, Griffin J, Granger CB, Califf RM, Van de Werf FJJ, Simes RJ, Muir AJ. Predictors of gastrointestinal bleeding in patients receiving thrombolytic therapies for acute ST-elevation myocardial infarction. 2004 Apr:A607-A607. Link to Item
  - Oliveira GBF, Newby LK, Lindblad L, Piegras LS, Verheught FW, Harrington RA, Hochman JS, White HD, Van de Werf F, Granger CB. White blood cell count predicts higher risk of intermediate-term outcomes in patients stabilized after acute coronary syndromes: Observations from the SYMPHONY and 2nd SYMPHONY trials. 2004 Mar 3:258A-258A. Full Text Link to Item
  - Patel MR, Mahaffey KW, Armstrong PW, Weaver WD, Tasissa G, Hochman JS, Todaro TG, Malloy KJ, Parish TH, Rollins S, Theroux P, Ruzyllo W, Nicolau JC, Granger CB. Baseline white blood cell count and interleukin-6 levels provide complementary prognostic information in acute myocardial infarction: Results from the CARDINAL trial. 2004 Mar 3:291A-292A. Full Text Link to Item
  - Crespo EM, Becker RC, Berger PB, Granger CB, Kleinman NS, Moliterno DJ, Moll S, Rice L, Abrams CS, Rogers J, Steinhubl SS, Tapson VF, Anstrom KJ, Ohman E. 1123-180 Incidence and evaluation of heparin-induced thrombocytopenia (HIT) among patients treated with prolonged heparin and among thrombocytopenic patients in the cardiac care unit: Preliminary results of the CATCH registry. 2004 Mar:A501-A501. Full Text
  - O'Meara E, McMurray J, Young J, Pfeffer M, Swedberg K, Yusuf S, Granger CB, Johansson P. Low haemoglobin is associated with more evidence of congestion but less severe systolic dysfunction in patients with chronic heart failure. 2004:498-498. Link to Item
  - Steg PHG, Dabbous OH, Lopez-Sendon J, Anderson FA, Gore JM, Kennelly BM, Granger CB, Fox KAA, Investigators GRACE. "Leading and lagging" hospitals: can processes of care be used to rank hospitals?. 2004:444-444. Link to Item
  - Young J, Swedberg K, Dunlap ME, Granger CB, McMurray JJV, Probstfield JL, Yusuf S, Pfeffer M. Substantial reduction in all-cause mortality and morbidity with candesartan in patients with chronic heart failure and systolic left ventricular dysfunction: results of the CHARM low EF trials. 2004:487-487. Link to Item
  - Rice L, Abrams CS, Anstrom KJ, Becker RC, Berger PB, Granger CB, Kleiman NS, Moliterno DJ, Moll S, Rogers J, Steinhubl SS, Tapson VF, Ohman EM. Thrombocytopenia is common among patients treated with heparin and is rarely detected and evaluated with serologic testing and hematology consultation: Preliminary findings from the CATCH registry. 2003 Nov 16:537A-537A. Link to Item
  - Armstrong PW, Wallentin L, Goldstein P, Granger CB, Bogaerts K, Danays T, Van de Werf F, Investigators ASSENT3, Investigators ASSENT3P. Meta-analysis of the efficacy and safety of unfractionated heparin versus enoxaparin in conjunction with tenecteplase for ST elevation myocardial infarction: Insights from ASSENT 3 and ASSENT 3 PLUS. 2003 Oct 28:580-581. Link to Item
  - Galla JM, Mahaffey KW, Sapp SK, Alexander JH, Granger CB, Harrington RA, Simoons ML, Newby LK. Elevated creatine kinase MB with normal creatine kinase predicts worse outcomes in patients with acute coronary syndromes: Results from four large clinical trials. 2003 Oct 28:377-377. Link to Item
  - Velazquez EJ, Jones WS, Smith WT, Kober L, Kilaru R, Rittenhouse LM, Granger CB, Weaver D, Lamas G, Zelenkofske SL, Aylward PE, Henis M, Swedberg K, Pfeffer MA, Van de Werf F, Rouleau JL, Califf RM. International assessment of atrial fibrillation in myocardial infarction: The VALIANT registry. 2003 Oct 28:425-425. Link to Item
  - Sadiq L, Lim MJ, Eagle KA, Gore JM, Goldberg RJ, Mehta RH, Granger CB, Dabbous OH, Spencer FA. Treating patients with non-ST-elevation acute coronary syndromes with aggressive antiplatelet agents in the GRACE registry: No observed improvement in hospital outcomes. 2003 Sep 15:232L-232L. Link to Item
  - Fox KA, Goodman SG, Anderson FA, Granger CB, Moscucci M, Flather MD, Spencer FA, Budaj A, Dabbous OH, Gore JM. Influence of guidelines and results from major clinical trials on medical practice: Findings from the global registry of acute coronary events (GRACE). 2003 Mar 19:518A-518A. Link to Item
  - Roe MT, Giugliano RP, Tuttle R, Hasselblad V, Murphy S, Antman EM, Ohman EM, Harrington RA, Granger CB, Mahaffey KW, Cannon CP, Lincoff AM, Gibson CM, Armstrong PW, van de Werf FJ, Califf RM, Topol EJ, Braunwald E. Safety of adjunctive glycoprotein IIb/IIIa blockade during rescue/early percutaneous coronary intervention following full-dose fibrinolytic therapy for acute myocardial infarction. 2003 Mar 19:332A-332A. Link to Item
  - Sinnaeve PR, Antman EM, Ross AM, Hasselblad V, Van de Werf FJ, Granger CB. Enoxaparin is superior to unfractionated heparin after fibrinolysis in acute myocardial infarction: Meta-analysis of ASSENT-3, HART-II, and ENTIRE-TIMI-23 trials. 2003 Mar 19:334A-334A. Link to Item
  - Armstrong PW, Mahaffey KW, Weaver WD, Hochman JS, Theroux P, Rollins S, Todaro TG, Granger CB. Mechanism of pexelizumabs mortality benefit in acute myocardial infarction patients treated with primary percutaneous coronary intervention. 2003:199-199. Full Text Link to Item
  - Lim MJ, Eagle KA, Gore JM, Goldberg RJ, Mehta RH, Granger CB, Dabbous OH, Spencer FA, Investigators GRACE. Treating patients with acute coronary syndromes with aggressive anti-platelet agents in the grace registry: no observed decrease in in-hospital mortality but increased bleeding complications. 2003:547-547. Full Text Link to Item
  - Mahaffey KW, Armstrong F, Hochman JS, Nicolau JC, Ruzyllo W, Mojcik CF, Filloon T, Granger CB, Investigators CARDINAL. Does infarct size measured by creatine kinase-MB predict clinical outcomes after fibrinolysis and primary percutaneous coronary intervention?. 2003:301-301. Full Text Link to Item
  - Sinnaeve PR, Alexander JH, Armstrong PW, Huang Y, Wallentin L, Goldstein P, Van de Werf F, Granger CB. Enoxaparin versus unfractionated heparin with tenecteplase in the elderly: combined ASSENT-3 and ASSENT-3+ results. 2003:542-542. Full Text Link to Item
  - Welsh RC, Goldstein P, Chang WC, Wallentin L, Granger CB, Verheugt F, Van de Werf F, Armstrong PW, Investigators ASSENT3P. Understanding time to treatment in acute myocardial infarction: insights from ASSENT 3+. 2003:502-502. Full Text Link to Item
  - Granger CB, Pieper KS, Eikelboom J, Simes J, Yusuf S. Effect of direct thrombin inhibitors on reducing death and myocardial infarction in acute coronary syndromes is greater in patients undergoing percutaneous coronary intervention. 2002 Nov 5:494-494. Link to Item
  - Kaul P, Armstrong PW, Granger CB, Lee KL, Mark DB. Conservative management of acute myocardial infarction may cost lives in the long-term: US-Canada comparison of 5-year mortality in GUSTO-I. 2002 Nov 5:697-697. Link to Item
  - Kaul P, Armstrong PW, Granger CB, Van de Werf F, Mark DB. ASSENT-3 economic analysis: Costs of reperfusion strategies in acute myocardial infarction. 2002 Nov 5:758-758. Link to Item
  - Sinnaeve PR, Belmans A, Aylward P, Wallentin L, Granger CB, de Werf FV. Pulse pressure and risk of intracranial hemorrhage after thrombolysis for acute myocardial infarction results from GUSTO-1, ASSENT-2 and ASSENT-3 trials. 2002 Nov 5:400-400. Link to Item
  - Alexander J, Tuttle RH, Granger CB, Wallentin L, Verheugt FWA, Armstrong PW, Van de Werf FJ. TNK with reduced dose unfractionated heparin associated with similar efficacy and less bleeding: results from ASSENT-2 and ASSENT-3. 2002:638-638. Link to Item
  - Fox KAA, Goldberg RJ, Pieper K, Cannon CP, Van de Werfs F, Goodman SG, Dabbous O, Granger CB, Investigators GRACE. Predictors of in-hospital mortality in the global registry of acute coronary events (GRACE). 2002:626-626. Link to Item
  - Serebruany VL, Malinin A, Callahan KP, Binbrek AS, van de Werf F, Alexander JH, Granger CB, Gurbel P. Effect of tenecteplase versus alteplase on platelets in patients during the first three hours after acute myocardial infarction. 2002:267-267. Link to Item
  - Wagner G, Fu Y, Goodman SG, Granger CB, Wallentin L, de Werf FV, Armstrong P, Investigators ASSENTIII. How does ST-segment resolution one-hour after fibrinolysis for acute myocardial infarction predict final infarct size? Insights from ASSENT 3. 2002:266-266. Link to Item
  - McGuire DK, Granger CB. Diabetes and ischemic heart disease. 1999 Nov:S366-S375. Link to Item
- Journal Articles
  - Berwanger O, Nicolau JC, Carvalho AC, Jiang L, Goodman S, Nicholls SJ, Parkhomenko A, Averkov O, Tajer C, Malaga G, Kerr Saraiva JF, Fonseca F, Guimaraes HP, de Barros e Silva PGM, Damiani LP, Paisani DM, Lasagno CMR, Candido CT, Valeis N, Moia DDF, Piegas LS, Granger CB, White H, Lopes RD. Ticagrelor versus clopidogrel after fibrinolytic therapy in patients with ST-elevation myocardial infarction: Rationale and design of the ticagrelor in patients with ST elevation myocardial infarction treated with thrombolysis (TREAT) trial. American Heart Journal. 2018 Aug;202:89-96. Full Text
  - Friedman DJ, Granger CB. Uninterrupted apixaban for atrial fibrillation ablation is a reasonable alternative, but what is the significance of silent cerebral infarctions?. European Heart Journal. 2018 Aug;39(32):2956-2958. PubMed Central PMCID: 29788351. Full Text
  - Horowitz JD, De Caterina R, Heresztyn T, Alexander JH, Andersson U, Lopes RD, Steg PG, Hylek EM, Mohan P, Hanna M, Jansky P, Granger CB, Wallentin L, ARISTOTLE Investigators . Asymmetric and Symmetric Dimethylarginine Predict Outcomes in Patients With Atrial Fibrillation: An ARISTOTLE Substudy. Journal of the American College of Cardiology. 2018 Aug;72(7):721-733. PubMed Central PMCID: 30092948. Full Text
  - Lund LH, Claggett B, Liu J, Lam CS, Jhund PS, Rosano GM, Swedberg K, Yusuf S, Granger CB, Pfeffer MA, McMurray JJV, Solomon SD. Heart failure with mid-range ejection fraction in CHARM: characteristics, outcomes and effect of candesartan across the entire ejection fraction spectrum. European Journal of Heart Failure. 2018 Aug;20(8):1230-1239. PubMed Central PMCID: 29431256. Full Text
  - Vinereanu D, Wang A, Mulder H, Lopes RD, Jansky P, Lewis BS, Gersh BJ, Avezum A, Hanna M, Held C, Wallentin L, Granger CB, Alexander JH. Outcomes in anticoagulated patients with atrial fibrillation and with mitral or aortic valve disease. Heart (British Cardiac Society). 2018 Aug;104(15):1292-1299. PubMed Central PMCID: 29352007. Full Text
  - Angiolillo DJ, Goodman SG, Bhatt DL, Eikelboom JW, Price MJ, Moliterno DJ, Cannon CP, Tanguay J-F, Granger CB, Mauri L, Holmes DR, Gibson CM, Faxon DP. Antithrombotic Therapy in Patients With Atrial Fibrillation Treated With Oral Anticoagulation Undergoing Percutaneous Coronary Intervention: A North American Perspective-2018 Update. Circulation. 2018 Jul 31;138(5):527-536. (Academic Article) Full Text Link to Item
  - Filgueiras Filho NM, Feitosa Filho GS, Solla DJF, Argôlo FC, Guimarães PO, Paiva Filho IDM, Carvalho LGM, Teixeira LS, Rios MNDO, Câmara SF, Novais VO, Barbosa LDS, Ballalai CS, De Lúcia CV, Granger CB, Newby LK, Lopes RD. Implementation of a Regional Network for ST-Segment-Elevation Myocardial Infarction (STEMI) Care and 30-Day Mortality in a Low- to Middle-Income City in Brazil: Findings From Salvador's STEMI Registry (RESISST). Journal of the American Heart Association. 2018 Jul 6;7(14). PubMed Central PMCID: 29980522. Full Text
  - Granger CB, Kochar A. Understanding and Targeting Inflammation in Acute Myocardial Infarction: An Elusive Goal. Journal of the American College of Cardiology. 2018 Jul;72(2):199-201. PubMed Central PMCID: 29976294. Full Text
  - Rymer JA, Tempelhof MW, Clare RM, Pieper KS, Granger CB, Van de Werf F, Moliterno DJ, Harrington RA, White HD, Armstrong PW, Lopes RD, Mahaffey KW, Newby LK. Discharge timing and outcomes after uncomplicated non-ST-segment elevation acute myocardial infarction. American Heart Journal. 2018 Jul;201:103-110. PubMed Central PMCID: 29910048. Full Text
  - Green JB, Hernandez AF, D'Agostino RB, Granger CB, Janmohamed S, Jones NP, Leiter LA, Noronha D, Russell R, Sigmon K, Del Prato S, McMurray JJV. Harmony Outcomes: A randomized, double-blind, placebo-controlled trial of the effect of albiglutide on major cardiovascular events in patients with type 2 diabetes mellitus-Rationale, design, and baseline characteristics. American Heart Journal. 2018 Jun 12;203:30-38. PubMed Central PMCID: 30015066. Full Text
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  - McCarthy JJ, Carr B, Sasson C, Bobrow BJ, Callaway CW, Neumar RW, Ferrer JME, Garvey JL, Ornato JP, Gonzales L, Granger CB, Kleinman ME, Bjerke C, Nichol G. Out-of-Hospital Cardiac Arrest Resuscitation Systems of Care: A Scientific Statement From the American Heart Association. Circulation. 2018 May 22;137(21):e645-e660. Full Text
  - Berwanger O, Nicolau JC, Carvalho AC, Jiang L, Goodman SG, Nicholls SJ, Parkhomenko A, Averkov O, Tajer C, Malaga G, Saraiva JFK, Fonseca FA, De Luca FA, Guimaraes HP, de Barros E Silva PGM, Damiani LP, Paisani DM, Lasagno CMR, Candido CT, Valeis N, Moia DDF, Piegas LS, Granger CB, White HD, Lopes RD, TREAT Study Group . Ticagrelor vs Clopidogrel After Fibrinolytic Therapy in Patients With ST-Elevation Myocardial Infarction: A Randomized Clinical Trial. Jama Cardiology. 2018 May;3(5):391-399. PubMed Central PMCID: 29525822. Full Text
  - Madhavan MV, Gersh BJ, Alexander KP, Granger CB, Stone GW. Coronary Artery Disease in Patients ≥80 Years of Age. Journal of the American College of Cardiology. 2018 May;71(18):2015-2040. PubMed Central PMCID: 29724356. (Review) Full Text
  - Berwanger O, Santucci EV, de Barros E Silva PGM, Jesuíno IDA, Damiani LP, Barbosa LM, Santos RHN, Laranjeira LN, Egydio FDM, Borges de Oliveira JA, Dall Orto FTC, Beraldo de Andrade P, Bienert IRDC, Bosso CE, Mangione JA, Polanczyk CA, Sousa AGDMR, Kalil RAK, Santos LDM, Sposito AC, Rech RL, Sousa ACS, Baldissera F, Nascimento BR, Giraldez RRCV, Cavalcanti AB, Pereira SB, Mattos LA, Armaganijan LV, Guimarães HP, Sousa JEMR, Alexander JH, Granger CB, Lopes RD, SECURE-PCI Investigators . Effect of Loading Dose of Atorvastatin Prior to Planned Percutaneous Coronary Intervention on Major Adverse Cardiovascular Events in Acute Coronary Syndrome: The SECURE-PCI Randomized Clinical Trial. Jama. 2018 Apr;319(13):1331-1340. PubMed Central PMCID: 29525821. Full Text
  - Berwanger O, de Barros e Silva PGM, Dall Orto FTC, de Andrade PB, de Castro Bienert IR, Bosso CE, Mangione J, Polanczyk CA, Sousa A, Kalil R, de Moura Santos L, Sposito AC, Rech RL, Sousa ACS, Baldissera F, Nascimento BR, de Andrade Jesuíno I, Santucci EV, Damiani LP, Laranjeira LN, Borges de Oliveira JA, Giraldez RR, Cavalcanti AB, Pereira SB, Mattos LA, Armaganijan LV, Guimarães HP, Sousa JE, Alexander JH, Granger CB, Lopes RD. Rationale and design of the Statins Evaluation in Coronary procedUres and REvascularization: The SECURE-PCI Trial. American Heart Journal. 2018 Apr;198:129-134. Full Text
  - Goto S, Merrill P, Wallentin L, Wojdyla DM, Hanna M, Avezum A, Easton JD, Harjola V-P, Huber K, Lewis BS, Parkhomenko A, Zhu J, Granger CB, Lopes RD, Alexander JH. Antithrombotic therapy use and clinical outcomes following thrombo-embolic events in patients with atrial fibrillation: insights from ARISTOTLE. European Heart Journal. Cardiovascular Pharmacotherapy. 2018 Apr;4(2):75-81. PubMed Central PMCID: 29385429. Full Text
  - Bahit MC, Kochar A, Granger CB. Post-Myocardial Infarction Heart Failure. Jacc. Heart Failure. 2018 Mar;6(3):179-186. PubMed Central PMCID: 29496021. (Review) Full Text
  - Kopin D, Jones WS, Sherwood MW, Wojdyla DM, Wallentin L, Lewis BS, Verheugt FWA, Vinereanu D, Bahit MC, Halvorsen S, Huber K, Parkhomenko A, Granger CB, Lopes RD, Alexander JH. Percutaneous coronary intervention and antiplatelet therapy in patients with atrial fibrillation receiving apixaban or warfarin: Insights from the ARISTOTLE trial. American Heart Journal. 2018 Mar;197:133-141. PubMed Central PMCID: 29447773. Full Text
  - Lopes RD, Rordorf R, De Ferrari GM, Leonardi S, Thomas L, Wojdyla DM, Ridefelt P, Lawrence JH, De Caterina R, Vinereanu D, Hanna M, Flaker G, Al-Khatib SM, Hohnloser SH, Alexander JH, Granger CB, Wallentin L, ARISTOTLE Committees and Investigators . Digoxin and Mortality in Patients With Atrial Fibrillation. Journal of the American College of Cardiology. 2018 Mar;71(10):1063-1074. PubMed Central PMCID: 29519345. Full Text
  - Rao MP, Vinereanu D, Wojdyla DM, Alexander JH, Atar D, Hylek EM, Hanna M, Wallentin L, Lopes RD, Gersh BJ, Granger CB, Apixaban for Reduction in Stroke Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Investigators . Clinical Outcomes and History of Fall in Patients with Atrial Fibrillation Treated with Oral Anticoagulation: Insights From the ARISTOTLE Trial. The American Journal of Medicine. 2018 Mar;131(3):269-275.e2. PubMed Central PMCID: 29122636. Full Text
  - Wolsk E, Claggett B, Køber L, Pocock S, Yusuf S, Swedberg K, McMurray JJV, Granger CB, Pfeffer MA, Solomon SD. Contribution of cardiac and extra-cardiac disease burden to risk of cardiovascular outcomes varies by ejection fraction in heart failure. European journal of heart failure. 2018 Mar;20(3):504-510. PubMed PMID: 29193462. Full Text
  - Carnicelli AP, Granger CB. Sodium bicarb vs sodium chloride, and acetylcysteine vs placebo, did not differ for adverse events after angiography. ANNALS OF INTERNAL MEDICINE. 2018 Feb 20;168(4):JC22-JC22. Full Text Link to Item
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  - Platz E, Jhund PS, Claggett BL, Pfeffer MA, Swedberg K, Granger CB, Yusuf S, Solomon SD, McMurray JJ. Prevalence and prognostic importance of precipitating factors leading to heart failure hospitalization: recurrent hospitalizations and mortality. European journal of heart failure. 2018 Feb;20(2):295-303. PubMed PMID: 28872259. Full Text
  - Pol T, Held C, Westerbergh J, Lindbäck J, Alexander JH, Alings M, Erol C, Goto S, Halvorsen S, Huber K, Hanna M, Lopes RD, Ruzyllo W, Granger CB, Hijazi Z. Dyslipidemia and Risk of Cardiovascular Events in Patients With Atrial Fibrillation Treated With Oral Anticoagulation Therapy: Insights From the ARISTOTLE (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation) Trial. Journal of the American Heart Association. 2018 Feb;7(3). PubMed Central PMCID: 29419390. Full Text
  - Hagström E, Norlund F, Stebbins A, Armstrong PW, Chiswell K, Granger CB, López-Sendón J, Pella D, Soffer J, Sy R, Wallentin L, White HD, Stewart RAH, Held C. Psychosocial stress and major cardiovascular events in patients with stable coronary heart disease. Journal of Internal Medicine. 2018 Jan;283(1):83-92. PubMed Central PMCID: 28960596. Full Text
  - Jollis JG, Al-Khalidi HR, Roettig ML, Berger PB, Corbett CC, Doerfler SM, Fordyce CB, Henry TD, Hollowell L, Magdon-Ismail Z, Kochar A, McCarthy JJ, Monk L, O'Brien P, Rea TD, Shavadia J, Tamis-Holland J, Wilson BH, Ziada KM, Granger CB. Impact of Regionalization of ST-Segment-Elevation Myocardial Infarction Care on Treatment Times and Outcomes for Emergency Medical Services-Transported Patients Presenting to Hospitals With Percutaneous Coronary Intervention: Mission: Lifeline Accelerator-2. Circulation. 2018 Jan;137(4):376-387. PubMed Central PMCID: 29138292. Full Text
  - Westermann D, Goodman SG, Nicolau JC, Requena G, Maguire A, Chen JY, Granger CB, Grieve R, Pocock SJ, Blankenberg S, Vega AM, Yasuda S, Simon T, Brieger D, TIGRIS Study Investigators . Rationale and design of the long-Term rIsk, clinical manaGement, and healthcare Resource utilization of stable coronary artery dISease in post-myocardial infarction patients (TIGRIS) study. Clinical Cardiology. 2017 Dec 16;40(12):1197-1204. PubMed Central PMCID: 29247524. Full Text
  - Pokorney SD, Granger CB. Traumatic injury: another unjustified reason to stop oral anticoagulation for atrial fibrillation. European heart journal. 2017 Dec 13. PubMed PMID: 29244070. Full Text
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  - Kristensen SL, Jhund PS, Lee MMY, Køber L, Solomon SD, Granger CB, Yusuf S, Pfeffer MA, Swedberg K, McMurray JJV, CHARM Investigators and Committees . Prevalence of Prediabetes and Undiagnosed Diabetes in Patients with HFpEF and HFrEF and Associated Clinical Outcomes. Cardiovascular Drugs and Therapy. 2017 Dec;31(5-6):545-549. PubMed Central PMCID: 28948430. Full Text
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  - Bossard M, Granger CB, Tanguay J-F, Montalescot G, Faxon DP, Jolly SS, Widimsky P, Niemela K, Steg PG, Natarajan MK, Gao P, Fox KAA, Yusuf S, Mehta SR. Double-Dose Versus Standard-Dose Clopidogrel According to Smoking Status Among Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention. Journal of the American Heart Association. 2017 Nov 3;6(11). PubMed Central PMCID: 29101117. Full Text
  - Ebinger J, Granger CB, Zhu A, Chang A, Henry TD. Idarucizumab since FDA approval: Use in the real-world. American Heart Journal. 2017 Nov;193:93-94. PubMed Central PMCID: 29129261. (Letter) Full Text
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  - Stewart RAH, Held C, Hadziosmanovic N, Armstrong PW, Cannon CP, Granger CB, Hagström E, Hochman JS, Koenig W, Lonn E, Nicolau JC, Steg PG, Vedin O, Wallentin L, White HD, STABILITY Investigators . Physical Activity and Mortality in Patients With Stable Coronary Heart Disease. Journal of the American College of Cardiology. 2017 Oct;70(14):1689-1700. PubMed Central PMCID: 28958324. Full Text
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  - Bernstein RA, Kamel H, Granger CB, Kowal RC, Ziegler PD, Schwamm LH. Stroke of Known Cause and Underlying Atrial Fibrillation (STROKE-AF) randomized trial: Design and rationale. American Heart Journal. 2017 Aug;190:19-24. PubMed Central PMCID: 28760209. Full Text
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  - Rymer JA, Granger CB. Review: A single hs-cTnT with a cutpoint < limit of detection plus a nonischemic ECG can rule out acute MI. Annals of internal medicine. 2017 Aug;167(4):JC23-. PubMed PMID: 28806804. Full Text
  - van Diepen S, Fordyce CB, Wegermann ZK, Granger CB, Stebbins A, Morrow DA, Solomon MA, Soble J, Henry TD, Gilchrist IC, Katz JN, Cohen MG, Newby LK. Organizational Structure, Staffing, Resources, and Educational Initiatives in Cardiac Intensive Care Units in the United States: An American Heart Association Acute Cardiac Care Committee and American College of Cardiology Critical Care Cardiology Working Group Cross-Sectional Survey. Circulation. Cardiovascular Quality and Outcomes. 2017 Aug;10(8):e003864-null. PubMed Central PMCID: 28794122. Full Text
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  - Mehta S, Granger C, Grines CL, Jacobs A, Henry TD, Rokos I, Lansky A, Baumbach A, Botelho R, Ferre A, Yepes I, Salwan R, Dalal J, Makkar J, Bhalla N, Mishra S, Vijan V, Hiremath S. Confronting system barriers for ST- elevation MI in low and middle income countries with a focus on India. Indian Heart Journal. 2017 Jul. Full Text
  - Shen L, Jhund PS, Petrie MC, Claggett BL, Barlera S, Cleland JGF, Dargie HJ, Granger CB, Kjekshus J, Køber L, Latini R, Maggioni AP, Packer M, Pitt B, Solomon SD, Swedberg K, Tavazzi L, Wikstrand J, Zannad F, Zile MR, McMurray JJV. Declining Risk of Sudden Death in Heart Failure. The New England Journal of Medicine. 2017 Jul;377(1):41-51. PubMed Central PMCID: 28679089. Full Text
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  - Fordyce CB, Douglas PS, Roberts RS, Hoffmann U, Al-Khalidi HR, Patel MR, Granger CB, Kostis J, Mark DB, Lee KL, Udelson JE, Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) Investigators . Identification of Patients With Stable Chest Pain Deriving Minimal Value From Noninvasive Testing: The PROMISE Minimal-Risk Tool, A Secondary Analysis of a Randomized Clinical Trial. JAMA cardiology. 2017 Apr;2(4):400-408. PubMed PMID: 28199464. Full Text
  - Mehta S, Granger CB, Henry TD, Grines CL, Lansky A, Rokos I, Botelho R, Baumbach A, Mishra S, Cheem TH, Tresukosol D, Zambahari R, Ferré A, Castillo M. Reducing system delays in treatment of ST elevation myocardial infarction and confronting the challenges of late presentation in low and middle-income countries. Indian Heart Journal. 2017 Apr;69:S1-S5. Full Text
  - Diener H-C, Aisenberg J, Ansell J, Atar D, Breithardt G, Eikelboom J, Ezekowitz MD, Granger CB, Halperin JL, Hohnloser SH, Hylek EM, Kirchhof P, Lane DA, Verheugt FWA, Veltkamp R, Lip GYH. Choosing a particular oral anticoagulant and dose for stroke prevention in individual patients with non-valvular atrial fibrillation: part 2. European Heart Journal. 2017 Mar;38(12):860-868. PubMed Central PMCID: 26848150. (Review) Full Text
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  - Henry TD, Granger CB. Out-of-Hospital Cardiac Arrest: To CT or Not to CT?. JACC. Cardiovascular interventions. 2017 Mar;10(5):460-461. PubMed PMID: 28279313. Full Text
  - Hess PL, Healey JS, Granger CB, Connolly SJ, Ziegler PD, Alexander JH, Kowey PR, Ruff CT, Flaker G, Halperin JL, Hart RG, Lopes RD. The Role of Cardiovascular Implantable Electronic Devices in the Detection and Treatment of Subclinical Atrial Fibrillation: A Review. Jama Cardiology. 2017 Mar;2(3):324-331. PubMed Central PMCID: 28097334. Full Text
  - Pagidipati NJ, Granger CB. Guideline: The USPSTF recommends low- to moderate-dose statins to prevent CVD in selected adults 40 to 75 years of age. Annals of internal medicine. 2017 Mar;166(6):JC26-. PubMed PMID: 28320000. Full Text
  - Peterson BE, Al-Khatib SM, Granger CB. Apixaban to prevent stroke in patients with atrial fibrillation: a review. Therapeutic advances in cardiovascular disease. 2017 Mar;11(3):91-104. PubMed PMID: 27342651. (Review) Full Text
  - Westenbrink BD, Alings M, Granger CB, Alexander JH, Lopes RD, Hylek EM, Thomas L, Wojdyla DM, Hanna M, Keltai M, Steg PG, De Caterina R, Wallentin L, van Gilst WH. Anemia is associated with bleeding and mortality, but not stroke, in patients with atrial fibrillation: Insights from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial. American Heart Journal. 2017 Mar;185:140-149. PubMed Central PMCID: 28267467. Full Text
  - Hu PT, Lopes RD, Stevens SR, Wallentin L, Thomas L, Alexander JH, Hanna M, Lewis BS, Verheugt FWA, Granger CB, Jones WS. Efficacy and Safety of Apixaban Compared With Warfarin in Patients With Atrial Fibrillation and Peripheral Artery Disease: Insights From the ARISTOTLE Trial. Journal of the American Heart Association. 2017 Jan 17;6(1). PubMed Central PMCID: 28096100. Full Text
  - Fordyce CB, Al-Khalidi HR, Jollis JG, Roettig ML, Gu J, Bagai A, Berger PB, Corbett CC, Dauerman HL, Fox K, Garvey JL, Henry TD, Rokos IC, Sherwood MW, Wilson BH, Granger CB, STEMI Systems Accelerator Project . Association of Rapid Care Process Implementation on Reperfusion Times Across Multiple ST-Segment-Elevation Myocardial Infarction Networks. Circulation. Cardiovascular interventions. 2017 Jan;10(1). PubMed PMID: 28082714. Full Text
  - Guimarães PO, Wojdyla DM, Alexander JH, Thomas L, Alings M, Flaker GC, Al-Khatib SM, Hanna M, Horowitz JD, Wallentin L, Granger CB, Lopes RD. Anticoagulation therapy and clinical outcomes in patients with recently diagnosed atrial fibrillation: Insights from the ARISTOTLE trial. International Journal of Cardiology. 2017 Jan;227:443-449. PubMed Central PMCID: 27852444. Full Text
  - Piccini JP, Granger CB. Insulin Therapy and Stroke Risk in Patients With Diabetes and Atrial Fibrillation: Guilty by Association?. Journal of the American College of Cardiology. 2017 Jan;69(4):420-422. PubMed PMID: 28126159. Full Text
  - Damman K, Solomon SD, Pfeffer MA, Swedberg K, Yusuf S, Young JB, Rouleau JL, Granger CB, McMurray JJV. Worsening renal function and outcome in heart failure patients with reduced and preserved ejection fraction and the impact of angiotensin receptor blocker treatment: data from the CHARM-study programme. European Journal of Heart Failure. 2016 Dec;18(12):1508-1517. PubMed Central PMCID: 27427441. Full Text
  - Jollis JG, Granger CB. Improving Care of Out-of-Hospital Cardiac Arrest: Next Steps. Circulation. 2016 Dec;134(25):2040-2042. PubMed Central PMCID: 27994023. Full Text
  - Kelly JP, Granger CB. More Evidence That Caffeine Consumption Appears to Be Safe in Patients With Heart Failure. Jama Internal Medicine. 2016 Dec;176(12):1759-1760. PubMed Central PMCID: 27749959. Full Text
  - Angiolillo DJ, Goodman SG, Bhatt DL, Eikelboom JW, Price MJ, Moliterno DJ, Cannon CP, Tanguay J-F, Granger CB, Mauri L, Holmes DR, Gibson CM, Faxon DP. Antithrombotic Therapy in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention: A North American Perspective-2016 Update. Circulation. Cardiovascular Interventions. 2016 Nov;9(11). PubMed Central PMCID: 27803042. (Review) Full Text
  - Garvey JL, Granger C, Peacock WF. Pushing the Envelope on STEMI Response. Ed Management : the Monthly Update on Emergency Department Management. 2016 Nov;28(11):121-126. PubMed Central PMCID: 29211410.
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  - Levine GN, Bates ER, Bittl JA, Brindis RG, Fihn SD, Fleisher LA, Granger CB, Lange RA, Mack MJ, Mauri L, Mehran R, Mukherjee D, Newby LK, O'Gara PT, Sabatine MS, Smith PK, Smith SC, Halperin JL, Al-Khatib SM, Birtcher KK, Bozkurt B, Cigarroa JE, Curtis LH, Gentile F, Gidding S, Hlatky MA, Ikonomidis JS, Joglar JA, Pressler SJ, Wijeysundera DN. 2016 ACC/AHA guideline focused update on duration of dual antiplatelet therapy in patients with coronary artery disease: A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. The Journal of Thoracic and Cardiovascular Surgery. 2016 Nov;152(5):1243-1275. PubMed Central PMCID: 27751237. Full Text
  - Oldgren J, Hijazi Z, Lindbäck J, Alexander JH, Connolly SJ, Eikelboom JW, Ezekowitz MD, Granger CB, Hylek EM, Lopes RD, Siegbahn A, Yusuf S, Wallentin L, RE-LY and ARISTOTLE Investigators . Performance and Validation of a Novel Biomarker-Based Stroke Risk Score for Atrial Fibrillation. Circulation. 2016 Nov;134(22):1697-1707. PubMed Central PMCID: 27569438. Full Text
  - Loley C, Alver M, Assimes TL, Bjonnes A, Goel A, Gustafsson S, Hernesniemi J, Hopewell JC, Kanoni S, Kleber ME, Lau KW, Lu Y, Lyytikäinen L-P, Nelson CP, Nikpay M, Qu L, Salfati E, Scholz M, Tukiainen T, Willenborg C, Won H-H, Zeng L, Zhang W, Anand SS, Beutner F, Bottinger EP, Clarke R, Dedoussis G, Do R, Esko T, Eskola M, Farrall M, Gauguier D, Giedraitis V, Granger CB, Hall AS, Hamsten A, Hazen SL, Huang J, Kähönen M, Kyriakou T, Laaksonen R, Lind L, Lindgren C, Magnusson PKE, Marouli E, Mihailov E, Morris AP, Nikus K, Pedersen N, Rallidis L, Salomaa V, Shah SH, Stewart AFR, Thompson JR, Zalloua PA, Chambers JC, Collins R, Ingelsson E, Iribarren C, Karhunen PJ, Kooner JS, Lehtimäki T, Loos RJF, März W, McPherson R, Metspalu A, Reilly MP, Ripatti S, Sanghera DK, Thiery J, Watkins H, Deloukas P, Kathiresan S, Samani NJ, Schunkert H, Erdmann J, König IR. No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis. Scientific Reports. 2016 Oct 12;6:35278-null. PubMed Central PMCID: 27731410. Full Text
  - Fordyce CB, Henry TD, Granger CB. Implementation of Regional ST-Segment Elevation Myocardial Infarction Systems of Care: Successes and Challenges. Interventional cardiology clinics. 2016 Oct;5(4):415-425. PubMed PMID: 28581992. (Review) Full Text
  - Le May M, van Diepen S, Liszkowski M, Schnell G, Tanguay J-F, Granger CB, Ainsworth C, Diodati JG, Fam N, Haichin R, Jassal D, Overgaard C, Tymchak W, Tyrrell B, Osborne C, Wong G. From Coronary Care Units to Cardiac Intensive Care Units: Recommendations for Organizational, Staffing, and Educational Transformation. The Canadian Journal of Cardiology. 2016 Oct;32(10):1204-1213. PubMed Central PMCID: 26968391. Full Text
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  - van Diepen S, Alemayehu WG, Zheng Y, Theroux P, Newby LK, Mahaffey KW, Granger CB, Armstrong PW. Temporal changes in biomarkers and their relationships to reperfusion and to clinical outcomes among patients with ST segment elevation myocardial infarction. Journal of thrombosis and thrombolysis. 2016 Oct;42(3):376-385. PubMed PMID: 27324144. Full Text
  - Alexander JH, Andersson U, Lopes RD, Hijazi Z, Hohnloser SH, Ezekowitz JA, Halvorsen S, Hanna M, Commerford P, Ruzyllo W, Huber K, Al-Khatib SM, Granger CB, Wallentin L, Apixaban for Reduction of Stroke and Other Thromboembolic Complications in Atrial Fibrillation (ARISTOTLE) Investigators . Apixaban 5 mg Twice Daily and Clinical Outcomes in Patients With Atrial Fibrillation and Advanced Age, Low Body Weight, or High Creatinine: A Secondary Analysis of a Randomized Clinical Trial. Jama Cardiology. 2016 Sep;1(6):673-681. PubMed Central PMCID: 27463942. Full Text
  - Arbel Y, FitzGerald G, Yan AT, Tan MK, Fox KAA, Gore JM, Steg PG, Eagle KA, Brieger D, Montalescot G, Budaj A, Lopez-Sendon J, Avezum A, Granger CB, Goodman SG. Temporal trends in all-cause mortality according to smoking status: Insights from the Global Registry of Acute Coronary Events. International Journal of Cardiology. 2016 Sep;218:291-297. PubMed Central PMCID: 27240154. Full Text
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  - Hawkins NM, Jhund PS, Pozzi A, O'Meara E, Solomon SD, Granger CB, Yusuf S, Pfeffer MA, Swedberg K, Petrie MC, Virani S, McMurray JJV. Severity of renal impairment in patients with heart failure and atrial fibrillation: implications for non-vitamin K antagonist oral anticoagulant dose adjustment. European Journal of Heart Failure. 2016 Sep;18(9):1162-1171. PubMed Central PMCID: 27594177. Full Text
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  - Rao MP, Dupre ME, Pokorney SD, Hansen CM, Tyson C, Monk L, Pearson DA, Nelson RD, Myers B, Jollis JG, Granger CB. Therapeutic Hypothermia for Patients with Out-of-Hospital Cardiac Arrest in North Carolina. Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors. 2016 Sep;20(5):630-636. PubMed PMID: 26985981. Full Text
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  - Pearson DA, Darrell Nelson R, Monk L, Tyson C, Jollis JG, Granger CB, Corbett C, Garvey L, Runyon MS. Comparison of team-focused CPR vs standard CPR in resuscitation from out-of-hospital cardiac arrest: Results from a statewide quality improvement initiative. Resuscitation. 2016 Aug;105:165-172. PubMed PMID: 27131844. Full Text
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  - Hijazi Z, Oldgren J, Lindbäck J, Alexander JH, Connolly SJ, Eikelboom JW, Ezekowitz MD, Held C, Hylek EM, Lopes RD, Siegbahn A, Yusuf S, Granger CB, Wallentin L, ARISTOTLE and RE-LY Investigators . The novel biomarker-based ABC (age, biomarkers, clinical history)-bleeding risk score for patients with atrial fibrillation: a derivation and validation study. Lancet (London, England). 2016 Jun;387(10035):2302-2311. PubMed Central PMCID: 27056738. Full Text
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  - Ruff CT, Ansell JE, Becker RC, Benjamin EJ, Deicicchi DJ, Mark Estes NA, Ezekowitz MD, Fanikos J, Fareed J, Garcia D, Giugliano RP, Goldhaber SZ, Granger C, Healey JS, Hull R, Hylek EM, Libby P, Lopes RD, Mahaffey KW, Mega J, Piazza G, Sasahara AA, Sorond FA, Spyropoulos AC, Walenga JM, Weitz JI. North American Thrombosis Forum, AF Action Initiative Consensus Document. The American Journal of Medicine. 2016 May;129(5 Suppl):S1-S29. PubMed Central PMCID: 27126598. Full Text
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  - Guimarães PO, Sun J-L, Kragholm K, Shah SH, Pieper KS, Kraus WE, Hauser ER, Granger CB, Newby LK, MURDOCK Horizon 1 Cardiovascular Study Investigators . Association of standard clinical and laboratory variables with red blood cell distribution width. American Heart Journal. 2016 Apr;174:22-28. PubMed Central PMCID: 26995366. Full Text
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  - Stone GW, Selker HP, Thiele H, Patel MR, Udelson JE, Ohman EM, Maehara A, Eitel I, Granger CB, Jenkins PL, Nichols M, Ben-Yehuda O. Relationship Between Infarct Size and Outcomes Following Primary PCI: Patient-Level Analysis From 10 Randomized Trials. Journal of the American College of Cardiology. 2016 Apr;67(14):1674-1683. PubMed Central PMCID: 27056772. Full Text
  - Albers GW, Bernstein RA, Brachmann J, Camm J, Easton JD, Fromm P, Goto S, Granger CB, Hohnloser SH, Hylek E, Jaffer AK, Krieger DW, Passman R, Pines JM, Reed SD, Rothwell PM, Kowey PR. Heart Rhythm Monitoring Strategies for Cryptogenic Stroke: 2015 Diagnostics and Monitoring Stroke Focus Group Report. Journal of the American Heart Association. 2016 Mar 15;5(3):e002944-null. PubMed Central PMCID: 27068633. (Review) Full Text
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  - Vinereanu D, Dulgheru R, Magda S, Dragoi Galrinho R, Florescu M, Cinteza M, Granger C, Ciobanu AO. The effect of indapamide versus hydrochlorothiazide on ventricular and arterial function in patients with hypertension and diabetes: results of a randomized trial. American heart journal. 2014 Oct;168(4):446-456. PubMed PMID: 25262253. Full Text
  - Christersson C, Wallentin L, Andersson U, Alexander JH, Ansell J, De Caterina R, Gersh BJ, Granger CB, Hanna M, Horowitz JD, Huber K, Husted S, Hylek EM, Lopes RD, Siegbahn A. D-dimer and risk of thromboembolic and bleeding events in patients with atrial fibrillation--observations from the ARISTOTLE trial. Journal of Thrombosis and Haemostasis : Jth. 2014 Sep;12(9):1401-1412. PubMed Central PMCID: 24942912. Full Text
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  - Karlsson LIM, Wissenberg M, Fosbøl EL, Hansen CM, Lippert FK, Bagai A, McNally B, Granger CB, Christensen EF, Folke F, Rajan S, Weeke P, Nielsen SL, Køber L, Gislason GH, Torp-Pedersen C. Diurnal variations in incidence and outcome of out-of-hospital cardiac arrest including prior comorbidity and pharmacotherapy: a nationwide study in Denmark. Resuscitation. 2014 Sep;85(9):1161-1168. PubMed PMID: 24971509. Full Text
  - Newby LK, Marber MS, Melloni C, Sarov-Blat L, Aberle LH, Aylward PE, Cai G, de Winter RJ, Hamm CW, Heitner JF, Kim R, Lerman A, Patel MR, Tanguay J-F, Lepore JJ, Al-Khalidi HR, Sprecher DL, Granger CB, SOLSTICE Investigators . Losmapimod, a novel p38 mitogen-activated protein kinase inhibitor, in non-ST-segment elevation myocardial infarction: a randomised phase 2 trial. Lancet (London, England). 2014 Sep;384(9949):1187-1195. PubMed Central PMCID: 24930728. Full Text
  - Steinberg BA, Broderick SH, Lopes RD, Shaw LK, Thomas KL, DeWald TA, Daubert JP, Peterson ED, Granger CB, Piccini JP. Use of antiarrhythmic drug therapy and clinical outcomes in older patients with concomitant atrial fibrillation and coronary artery disease. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 2014 Sep;16(9):1284-1290. PubMed PMID: 24755440. Full Text
  - Steinberg BA, Broderick SH, Lopes RD, Shaw LK, Thomas KL, DeWald TA, Daubert JP, Peterson ED, Granger CB, Piccini JP. Use of antiarrhythmic drug therapy and clinical outcomes in older patients with concomitant atrial fibrillation and coronary artery disease. EUROPACE. 2014 Sep;16(9):1284-1290. Full Text Link to Item
  - Bagai A, Wang Y, Wang TY, Curtis JP, Gurm HS, Shah B, Cheema AN, Peterson ED, Saucedo JF, Granger CB, Roe MT, Bhatt DL, McNamara RL, Alexander KP. In-hospital switching between clopidogrel and prasugrel among patients with acute myocardial infarction treated with percutaneous coronary intervention: insights into contemporary practice from the national cardiovascular data registry. Circulation. Cardiovascular Interventions. 2014 Aug 5;7(4):585-593. PubMed Central PMCID: 25097196. Full Text
  - Bao MH, Zheng Y, Westerhout CM, Fu Y, Wagner GS, Chaitman B, Granger CB, Armstrong PW. Prognostic implications of quantitative evaluation of baseline Q-wave width in ST-segment elevation myocardial infarction. Journal of electrocardiology. 2014 Jul;47(4):465-471. PubMed PMID: 24853083. Full Text
  - Bello NA, Claggett B, Desai AS, McMurray JJV, Granger CB, Yusuf S, Swedberg K, Pfeffer MA, Solomon SD. Influence of previous heart failure hospitalization on cardiovascular events in patients with reduced and preserved ejection fraction. Circulation. Heart Failure. 2014 Jul;7(4):590-595. PubMed Central PMCID: 24874200. Full Text
  - Diener H-C, Granger CB, Patel MR. Is there a period of liability with initiation of warfarin in patients with atrial fibrillation?. European heart journal. 2014 Jul;35(28):1834-1835. PubMed PMID: 24561547. Full Text
  - Halvorsen S, Atar D, Yang H, De Caterina R, Erol C, Garcia D, Granger CB, Hanna M, Held C, Husted S, Hylek EM, Jansky P, Lopes RD, Ruzyllo W, Thomas L, Wallentin L. Efficacy and safety of apixaban compared with warfarin according to age for stroke prevention in atrial fibrillation: observations from the ARISTOTLE trial. European Heart Journal. 2014 Jul;35(28):1864-1872. PubMed Central PMCID: 24561548. Full Text
  - Bagai A, Dangas GD, Stone GW, Granger CB. Reperfusion strategies in acute coronary syndromes. Circulation Research. 2014 Jun;114(12):1918-1928. PubMed Central PMCID: 24902975. (Review) Full Text
  - Bainey KR, Gafni A, Rao-Melacini P, Tong W, Steg PG, Faxon DP, Lamy A, Granger CB, Yusuf S, Mehta SR, TIMACS Investigators . The cost implications of an early versus delayed invasive strategy in Acute Coronary Syndromes: the TIMACS study. Journal of Medical Economics. 2014 Jun;17(6):415-422. PubMed Central PMCID: 24702256. Full Text
  - Granger CB, Rao MP. Assessing oral beta-blocker therapy after percutaneous coronary intervention for ST-segment elevation myocardial infarction: the role of observational data. JACC. Cardiovascular interventions. 2014 Jun;7(6):602-603. PubMed PMID: 24947718. Full Text
  - Huber K, Gersh BJ, Goldstein P, Granger CB, Armstrong PW. The organization, function, and outcomes of ST-elevation myocardial infarction networks worldwide: current state, unmet needs and future directions. European Heart Journal. 2014 Jun;35(23):1526-1532. PubMed Central PMCID: 24742888. (Review) Full Text
  - Hylek EM, Held C, Alexander JH, Lopes RD, De Caterina R, Wojdyla DM, Huber K, Jansky P, Steg PG, Hanna M, Thomas L, Wallentin L, Granger CB. Major bleeding in patients with atrial fibrillation receiving apixaban or warfarin: The ARISTOTLE Trial (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation): Predictors, Characteristics, and Clinical Outcomes. Journal of the American College of Cardiology. 2014 May;63(20):2141-2147. PubMed Central PMCID: 24657685. Full Text
  - Rogers JK, Pocock SJ, McMurray JJ, Granger CB, Michelson EL, Östergren J, Pfeffer MA, Solomon SD, Swedberg K, Yusuf S. Corrigendum to ‘Analysing recurrent hospitalizations in heart failure: a review of statistical methodology, with application to CHARM-Preserved’ [ Eur J Heart Fail 2014;16:33-40]. European Journal of Heart Failure. 2014 May;16(5):592-592. Full Text
  - STABILITY Investigators , White HD, Held C, Stewart R, Tarka E, Brown R, Davies RY, Budaj A, Harrington RA, Steg PG, Ardissino D, Armstrong PW, Avezum A, Aylward PE, Bryce A, Chen H, Chen M-F, Corbalan R, Dalby AJ, Danchin N, De Winter RJ, Denchev S, Diaz R, Elisaf M, Flather MD, Goudev AR, Granger CB, Grinfeld L, Hochman JS, Husted S, Kim H-S, Koenig W, Linhart A, Lonn E, López-Sendón J, Manolis AJ, Mohler ER, Nicolau JC, Pais P, Parkhomenko A, Pedersen TR, Pella D, Ramos-Corrales MA, Ruda M, Sereg M, Siddique S, Sinnaeve P, Smith P, Sritara P, Swart HP, Sy RG, Teramoto T, Tse H-F, Watson D, Weaver WD, Weiss R, Viigimaa M, Vinereanu D, Zhu J, Cannon CP, Wallentin L. Darapladib for preventing ischemic events in stable coronary heart disease. The New England Journal of Medicine. 2014 May;370(18):1702-1711. PubMed Central PMCID: 24678955. Full Text
  - Hart RG, Diener H-C, Coutts SB, Easton JD, Granger CB, O'Donnell MJ, Sacco RL, Connolly SJ, Cryptogenic Stroke/ESUS International Working Group . Embolic strokes of undetermined source: the case for a new clinical construct. The Lancet. Neurology. 2014 Apr;13(4):429-438. PubMed Central PMCID: 24646875. Full Text
  - Nelson JA, Vavalle JP, May CH, Zhang A, Newby LK, Shaw LK, Al-Khatib SM, Alexander JH, Granger CB, Lopes RD. Warfarin use and long-term outcomes in patients with acute myocardial infarction and atrial fibrillation. J Thromb Thrombolysis. 2014 Apr;37(3):331-337. PubMed PMID: 23733104. Full Text Link to Item
  - Rao MP, Granger CB. Improving integrated care in low- and middle-income countries: the final STEMI frontier?. Journal of interventional cardiology. 2014 Apr;27(2):167-170. PubMed PMID: 24697950. Full Text
  - Bagai A, Jollis JG, Dauerman HL, Peng SA, Rokos IC, Bates ER, French WJ, Granger CB, Roe MT. Response to letter regarding article, "Emergency department bypass for ST-segment-elevation myocardial infarction patients identified with a prehospital electrocardiogram: a report from the American Heart Association Mission: Lifeline Program". Circulation. 2014 Mar;129(9):e372-. PubMed PMID: 24589703. (Letter) Full Text
  - Calvo G, McMurray JJV, Granger CB, Alonso-García Á, Armstrong P, Flather M, Gómez-Outes A, Pocock S, Stockbridge N, Svensson A, Van de Werf F. Large streamlined trials in cardiovascular disease. European Heart Journal. 2014 Mar;35(9):544-548. PubMed Central PMCID: 24385376. Full Text
  - Flaker G, Lopes RD, Al-Khatib SM, Hermosillo AG, Hohnloser SH, Tinga B, Zhu J, Mohan P, Garcia D, Bartunek J, Vinereanu D, Husted S, Harjola VP, Rosenqvist M, Alexander JH, Granger CB, ARISTOTLE Committees and Investigators . Efficacy and safety of apixaban in patients after cardioversion for atrial fibrillation: insights from the ARISTOTLE Trial (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation). Journal of the American College of Cardiology. 2014 Mar;63(11):1082-1087. PubMed Central PMCID: 24211508. Full Text
  - Granger CB, Chertow GM. A pint of sweat will save a gallon of blood: a call for randomized trials of anticoagulation in end-stage renal disease. Circulation. 2014 Mar;129(11):1190-1192. PubMed PMID: 24452751. Full Text
  - Hijazi Z, Siegbahn A, Andersson U, Granger CB, Alexander JH, Atar D, Gersh BJ, Mohan P, Harjola VP, Horowitz J, Husted S, Hylek EM, Lopes RD, McMurray JJV, Wallentin L. High-sensitivity troponin I for risk assessment in patients with atrial fibrillation: Insights from the apixaban for reduction in stroke and other thromboembolic events in atrial fibrillation (ARISTOTLE) trial. Circulation. 2014 Feb 11;129(6):625-634. Full Text
  - Hijazi Z, Siegbahn A, Andersson U, Granger CB, Alexander JH, Atar D, Gersh BJ, Mohan P, Harjola V-P, Horowitz J, Husted S, Hylek EM, Lopes RD, McMurray JJV, Wallentin L, ARISTOTLE Investigators . High-sensitivity troponin I for risk assessment in patients with atrial fibrillation: insights from the Apixaban for Reduction in Stroke and other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial. Circulation. 2014 Feb;129(6):625-634. PubMed Central PMCID: 24226808. Full Text
  - Hijazi Z, Wallentin L, Siegbahn A, Andersson U, Alexander JH, Atar D, Gersh BJ, Hanna M, Harjola VP, Horowitz JD, Husted S, Hylek EM, Lopes RD, McMurray JJV, Granger CB, Investigators ARISTOTLE. High-Sensitivity Troponin T and Risk Stratification in Patients With Atrial Fibrillation During Treatment With Apixaban or Warfarin. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2014 Jan 7;63(1):52-61. Full Text Link to Item
  - Alexander JH, Lopes RD, Thomas L, Alings M, Atar D, Aylward P, Goto S, Hanna M, Huber K, Husted S, Lewis BS, McMurray JJV, Pais P, Pouleur H, Steg PG, Verheugt FWA, Wojdyla DM, Granger CB, Wallentin L. Apixaban vs. warfarin with concomitant aspirin in patients with atrial fibrillation: insights from the ARISTOTLE trial. European Heart Journal. 2014 Jan;35(4):224-232. PubMed Central PMCID: 24144788. Full Text
  - Bagai A, Al-Khalidi HR, Sherwood MW, Muñoz D, Roettig ML, Jollis JG, Granger CB. Regional systems of care demonstration project: Mission: Lifeline STEMI Systems Accelerator: design and methodology. American Heart Journal. 2014 Jan;167(1):15-21.e3. PubMed Central PMCID: 24332137. Full Text
  - Bagai A, Al-Khalidi HR, Sherwood MW, Muñoz D, Roettig ML, Jollis JG, Granger CB. Regional systems of care demonstration project: Mission: Lifeline STEMI Systems Accelerator: Design and methodology. American Heart Journal. 2014 Jan 1;167(1). Full Text
  - Bagai A, Schulte PJ, Granger CB, Mahaffey KW, Christenson RH, Bell G, Lopes RD, Green CL, Lincoff AM, Armstrong PW, Roe MT. Prognostic implications of creatine kinase-MB measurements in ST-segment elevation myocardial infarction patients treated with primary percutaneous coronary intervention. American Heart Journal. 2014 Jan 1;168(4):503-511.e2. Full Text
  - Bao MH, Zheng Y, Westerhout CM, Fu Y, Wagner GS, Chaitman B, Granger CB, Armstrong PW. Prognostic implications of quantitative evaluation of baseline Q-wave width in ST-segment elevation myocardial infarction. Journal of Electrocardiology. 2014 Jan 1;47(4):465-471. Full Text
  - Bhattacharya S, Granger CB, Craig D, Haynes C, Bain J, Stevens RD, Hauser ER, Newgard CB, Kraus WE, Newby LK, Shah SH. Validation of the association between a branched chain amino acid metabolite profile and extremes of coronary artery disease in patients referred for cardiac catheterization. Atherosclerosis. 2014 Jan;232(1):191-196. PubMed PMID: 24401236. Full Text Link to Item
  - Christersson C, Wallentin L, Andersson U, Alexander JH, Ansell J, De Caterina R, Gersh BJ, Granger CB, Hanna M, Horowitz JD, Huber K, Husted S, Hylek EM, Lopes RD, Siegbahn A. D-dimer and risk of thromboembolic and bleeding events in patients with atrial fibrillation - observations from the ARISTOTLE trial. Journal of Thrombosis and Haemostasis. 2014 Jan 1;12(9):1401-1412. Full Text
  - Granger CB, Becker LB. Randomized clinical trial progress to inform care for out-of-hospital cardiac arrest. JAMA. 2014 Jan 1;311(1):31-32. PubMed PMID: 24240668. Full Text Link to Item
  - Granger CB, Chertow GM. A pint of sweat will save a gallon of blood: A call for randomized trials of anticoagulation in end-stage renal disease. Circulation. 2014;129(11):1190-1192. Full Text
  - Granger CB, Lopes RD, Hanna M, Ansell J, Hylek EM, Alexander JH, Thomas L, Wang J, Bahit MC, Verheugt F, Lawrence J, Xavier D, Wallentin L. Clinical events after transitioning from apixaban versus warfarin to warfarin at the end of the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial. American Heart Journal. 2014 Jan 1;169(1):25-30. Full Text
  - Huber K, Bates ER, Valgimigli M, Wallentin L, Kristensen SD, Anderson JL, Lopez Sendon JL, Tubaro M, Granger CB, Bode C, Ohman EM, Steg PG. Antiplatelet and anticoagulation agents in acute coronary syndromes: What is the current status and what does the future hold?. American Heart Journal. 2014 Jan 1;168(5):611-621. Full Text
  - Karlsson LIM, Wissenberg M, Fosbøl EL, Hansen CM, Lippert FK, Bagai A, McNally B, Granger CB, Christensen EF, Folke F, Rajan S, Weeke P, Nielsen SL, Køber L, Gislason GH, Torp-Pedersen C. Diurnal variations in incidence and outcome of out-of-hospital cardiac arrest including prior comorbidity and pharmacotherapy: A nationwide study in Denmark. Resuscitation. 2014 Jan 1;85(9):1161-1168. Full Text
  - Nelson JA, Vavalle JP, May CH, Zhang A, Newby LK, Shaw LK, Al-Khatib SM, Alexander JH, Granger CB, Lopes RD. Warfarin use and long-term outcomes in patients with acute myocardial infarction and atrial fibrillation. Journal of Thrombosis and Thrombolysis. 2014 Jan 1;37(3):331-337. Full Text
  - Newby LK, Marber MS, Melloni C, Sarov-Blat L, Aberle LH, Aylward PE, Cai G, De Winter RJ, Hamm CW, Heitner JF, Kim R, Lerman A, Patel MR, Tanguay JF, Lepore JJ, Al-Khalidi HR, Sprecher DL, Granger CBI. Losmapimod, a novel p38 mitogen-activated protein kinase inhibitor, in non-ST-segment elevation myocardial infarction: A randomised phase 2 trial. The Lancet. 2014 Jan 1;384(9949):1187-1195. Full Text
  - Rao MP, Pokorney SD, Granger CB. Atrial fibrillation: a review of recent studies with a focus on those from the duke clinical research institute. Scientifica. 2014 Jan;2014:901586-. PubMed PMID: 25215263. (Review) Full Text
  - Rogers JK, Pocock SJ, McMurray JJV, Granger CB, Michelson EL, Östergren J, Pfeffer MA, Solomon SD, Swedberg K, Yusuf S. Analysing recurrent hospitalizations in heart failure: a review of statistical methodology, with application to CHARM-Preserved. European Journal of Heart Failure. 2014 Jan;16(1):33-40. PubMed Central PMCID: 24453096. (Review) Full Text
  - Vinereanu D, Dulgheru R, Magda S, Galrinho RD, Florescu M, Cinteza M, Granger C, Ciobanu AO. The effect of indapamide versus hydrochlorothiazide on ventricular and arterial function in patients with hypertension and diabetes: Results of a randomized trial. American Heart Journal. 2014;168(4):446-456. Full Text
  - Wallentin L, Lopes RD, Hanna M, Thomas L, Hellkamp A, Nepal S, Hylek EM, Al-Khatib SM, Alexander JH, Alings M, Amerena J, Ansell J, Aylward P, Bartunek J, Commerford P, De Caterina R, Erol C, Harjola V-P, Held C, Horowitz J, Huber K, Husted S, Keltai M, Lanas F, Lisheng L, McMurray JJV, Oh B-H, Rosenqvist M, Ruzyllo W, Steg PG, Vinereanu D, Xavier D, Granger CB. Response to letter regarding article, "Efficacy and safety of apixaban compared with warfarin at different levels of predicted international normalized ratio control for stroke prevention in atrial fibrillation". Circulation. 2014 Jan;129(2):e21-e22. PubMed PMID: 24421367. (Letter) Full Text
  - Bagai A, McNally BF, Al-Khatib SM, Myers JB, Kim S, Karlsson L, Torp-Pedersen C, Wissenberg M, van Diepen S, Fosbol EL, Monk L, Abella BS, Granger CB, Jollis JG. Temporal differences in out-of-hospital cardiac arrest incidence and survival. Circulation. 2013 Dec;128(24):2595-2602. PubMed Central PMCID: 24045044. Full Text
  - Bahit MC, Lopes RD, Wojdyla DM, Hohnloser SH, Alexander JH, Lewis BS, Aylward PE, Verheugt FWA, Keltai M, Diaz R, Hanna M, Granger CB, Wallentin L. Apixaban in patients with atrial fibrillation and prior coronary artery disease: Insights from the ARISTOTLE trial. International Journal of Cardiology. 2013 Dec;170(2):215-220. Full Text
  - Bagai A, Armstrong PW, Stebbins A, Mahaffey KW, Hochman JS, Weaver WD, Patel MR, Granger CB, Lopes RD. Prognostic implications of left ventricular end-diastolic pressure during primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: Findings from the Assessment of Pexelizumab in Acute Myocardial Infarction study. American Heart Journal. 2013 Nov;166(5):913-919. PubMed Central PMCID: 24176448. Full Text
  - Bagai A, Armstrong PW, Stebbins A, Mahaffey KW, Hochman JS, Weaver WD, Patel MR, Granger CB, Lopes RD. Prognostic implications of left ventricular end-diastolic pressure during primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: Findings from the Assessment of Pexelizumab in Acute Myocardial Infarction study. American Heart Journal. 2013 Nov 1;166(5):913-919. Full Text
  - Fosbol EL, Granger CB. Learning from regional heterogeneity in outcomes of patients with acute myocardial infarction. EUROPEAN HEART JOURNAL. 2013 Nov;34(41):3171-3172. PubMed PMID: 24046433. Full Text Link to Item
  - Stewart R, Held C, Brown R, Vedin O, Hagstrom E, Lonn E, Armstrong P, Granger CB, Hochman J, Davies R, Soffer J, Wallentin L, White H. Physical activity in patients with stable coronary heart disease: an international perspective. European Heart Journal. 2013 Nov;34(42):3286-3293. PubMed Central PMCID: 24014220. Full Text
  - Wong CM, Hawkins NM, Jhund PS, MacDonald MR, Solomon SD, Granger CB, Yusuf S, Pfeffer MA, Swedberg K, Petrie MC, McMurray JJV. Clinical characteristics and outcomes of young and very young adults with heart failure: The CHARM programme (Candesartan in Heart Failure Assessment of Reduction in Mortality and Morbidity). Journal of the American College of Cardiology. 2013 Nov;62(20):1845-1854. PubMed Central PMCID: 23850914. Full Text
  - Van Diepen S, Newby LK, Stebbins A, Armstrong PW, Granger CB. Response to letter "associations of inflammatory biomarkers to body mass index among patients with acute coronary syndrome". International Journal of Cardiology. 2013 Oct 9;168(4):4543-. (Letter) Full Text
  - van Diepen S, Newby LK, Stebbins A, Armstrong PW, Granger CB. Response to letter "associations of inflammatory biomarkers to body mass index among patients with acute coronary syndrome". Int J Cardiol. 2013 Oct 9;168(4):4543-. PubMed PMID: 23916777. (Letter) Full Text Link to Item
  - van Diepen S, Abella BS, Bobrow BJ, Nichol G, Jollis JG, Mellor J, Racht EM, Yannopoulos D, Granger CB, Sayre MR. Multistate implementation of guideline-based cardiac resuscitation systems of care: description of the HeartRescue project. Am Heart J. 2013 Oct;166(4):647-653.e2. PubMed PMID: 24093843. (Review) Full Text Link to Item
  - van Diepen S, Newby LK, Lopes RD, Stebbins A, Hasselblad V, James S, Roe MT, Ezekowitz JA, Moliterno DJ, Neumann F-J, Reist C, Mahaffey KW, Hochman JS, Hamm CW, Armstrong PW, Granger CB, Theroux P, APEX AMI Investigators . Prognostic relevance of baseline pro- and anti-inflammatory markers in STEMI: an APEX AMI substudy. International Journal of Cardiology. 2013 Oct;168(3):2127-2133. PubMed Central PMCID: 23394896. Full Text
  - Alexander JH, Levy E, Lawrence J, Hanna M, Waclawski AP, Wang J, Califf RM, Wallentin L, Granger CB. Documentation of study medication dispensing in a prospective large randomized clinical trial: experiences from the ARISTOTLE Trial. American Heart Journal. 2013 Sep;166(3):559-565. PubMed Central PMCID: 24016507. Full Text
  - Alonso A, Gore JM, Awad HH, Quill AL, Montalescot G, van de Werf F, Gulba DC, Fox KAA, Eagle KA, Granger CB, Wyman A, Steg PG, GRACE Investigators . Management and outcomes of patients presenting with STEMI by use of chronic oral anticoagulation: results from the GRACE registry. European Heart Journal. Acute Cardiovascular Care. 2013 Sep;2(3):280-291. PubMed Central PMCID: 24222840. Full Text
  - Eikelboom JW, Connolly SJ, Brueckmann M, Granger CB, Kappetein AP, Mack MJ, Blatchford J, Devenny K, Friedman J, Guiver K, Harper R, Khder Y, Lobmeyer MT, Maas H, Voigt J-U, Simoons ML, Van de Werf F, RE-ALIGN Investigators . Dabigatran versus warfarin in patients with mechanical heart valves. The New England Journal of Medicine. 2013 Sep;369(13):1206-1214. PubMed Central PMCID: 23991661. Full Text
  - Fullwood JE, Mostaghimi Z, Granger CB, Washam JB, Bride W, Zhao Y, Granger BB. Alcohol withdrawal prevention: a randomized evaluation of lorazepam and ethanol--a pilot study. Am J Crit Care. 2013 Sep;22(5):398-406. PubMed PMID: 23996419. Full Text Link to Item
  - Hess CN, Al-Khatib SM, Granger CB, Lopes R. A review of apixaban for stroke prevention in atrial fibrillation: insights from ARISTOTLE. Expert Rev Cardiovasc Ther. 2013 Sep;11(9):1105-1114. PubMed PMID: 23992517. (Review) Full Text Link to Item
  - Reith C, Landray M, Devereaux PJ, Bosch J, Granger CB, Baigent C, Califf RM, Collins R, Yusuf S. Randomized clinical trials--removing unnecessary obstacles. The New England Journal of Medicine. 2013 Sep;369(11):1061-1065. PubMed Central PMCID: 24024845. Full Text
  - van Diepen S, Vavalle JP, Newby LK, Clare R, Pieper KS, Ezekowitz JA, Hochman JS, Mahaffey KW, Armstrong PW, Granger CB. The systemic inflammatory response syndrome in patients with ST-segment elevation myocardial infarction. Critical Care Medicine. 2013 Sep;41(9):2080-2087. PubMed Central PMCID: 23760155. Full Text
  - Al-Khatib SM, Thomas L, Wallentin L, Lopes RD, Gersh B, Garcia D, Ezekowitz J, Alings M, Yang H, Alexander JH, Flaker G, Hanna M, Granger CB. Outcomes of apixaban vs. warfarin by type and duration of atrial fibrillation: results from the ARISTOTLE trial. European Heart Journal. 2013 Aug;34(31):2464-2471. PubMed Central PMCID: 23594592. Full Text
  - Bagai A, Al-Khalidi HR, Muñoz D, Monk L, Roettig ML, Corbett CC, Garvey JL, Wilson BH, Granger CB, Jollis JG. Bypassing the emergency department and time to reperfusion in patients with prehospital ST-segment-elevation: findings from the reperfusion in acute myocardial infarction in Carolina Emergency Departments project. Circ Cardiovasc Interv. 2013 Aug;6(4):399-406. PubMed PMID: 23861465. Full Text Link to Item
  - Desai J, Granger CB, Weitz JI, Aisenberg J. Novel oral anticoagulants in gastroenterology practice. Gastrointestinal Endoscopy. 2013 Aug;78(2):227-239. PubMed Central PMCID: 23725876. (Review) Full Text
  - Bagai A, Jollis JG, Dauerman HL, Peng SA, Rokos IC, Bates ER, French WJ, Granger CB, Roe MT. Emergency department bypass for ST-Segment-elevation myocardial infarction patients identified with a prehospital electrocardiogram: a report from the American Heart Association Mission: Lifeline program. Circulation. 2013 Jul 23;128(4):352-359. PubMed PMID: 23788525. Full Text Link to Item
  - Lopes RD, Becker RC, Newby LK, Peterson ED, Hylek EM, Giugliano R, Granger CB, Mahaffey KW, Carvalho AC, Berwanger O, Giraldez RR, Feitosa-Filho GS, Barbosa MM, da Consolacao V Moreira M, Kalil RAK, Freitas M, de Campos Guerra JC, Barros MVL, da Rocha Rodrigues T, Lopes AC, Garcia DA. Highlights from the fifth international symposium of thrombosis and anticoagulation (ISTA V), October 18-19, 2012, Belo Horizonte, Minas Gerais, Brazil. J Thromb Thrombolysis. 2013 Jul;36(1):115-130. PubMed PMID: 23494487. Full Text Link to Item
  - O'Gara PT, Kushner FG, Ascheim DD, Casey DE, Chung MK, de Lemos JA, Ettinger SM, Fang JC, Fesmire FM, Franklin BA, Granger CB, Krumholz HM, Linderbaum JA, Morrow DA, Newby LK, Ornato JP, Ou N, Radford MJ, Tamis-Holland JE, Tommaso CL, Tracy CM, Woo YJ, Zhao DX, American College of Cardiology Foundation , American Heart Association Task Force on Practice Guidelines , American College of Emergency Physicians , Society for Cardiovascular Angiography and Interventions . 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: developed in collaboration with the American College of Emergency Physicians and Society for Cardiovascular Angiography and Interventions. Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions. 2013 Jul;82(1):E1-27. PubMed Central PMCID: 23299937. (Review) Full Text
  - Bagai A, Granger CB. Acute coronary syndromes. STREAMlining care for patients with STEMI. Nature Reviews. Cardiology. 2013 Jun;10(6):304-306. PubMed Central PMCID: 23609173. Full Text
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  - Wong C, Hawkins NM, Jhund P, Solomon SD, Granger CB, Yusuf S, Pfeffer MA, Swedberg K, Petrie MC, Mcmurray JJV. Clinical characteristics and outcomes of young and very young adults with heart failure: the CHARM programme. EUROPEAN JOURNAL OF HEART FAILURE. 2013 May;12:S110-S110. Link to Item
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  - Rose JJ, Newby LK, Broderick S, Chiswell K, Van de Werf F, Armstrong PW, Mahaffey KW, Harrington RA, Ohman EM, Giugliano RP, Goodman SG, White HD, Califf RM, Granger CB, Lopes RD. Left bundle branch block in non-ST-segment elevation acute coronary syndromes. Incidence, angiographic characteristics, and clinical outcomes. Journal of the American College of Cardiology. 2013 Apr;61(13):1461-1463. PubMed Central PMCID: 23500249. (Letter) Full Text
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  - Fosbøl EL, Granger CB, Peterson ED, Lin L, Lytle BL, Shofer FS, Lohmeier C, Mears GD, Garvey JL, Corbett CC, Jollis JG, Glickman SW. Prehospital system delay in ST-segment elevation myocardial infarction care: a novel linkage of emergency medicine services and in hospital registry data. American Heart Journal. 2013 Mar;165(3):363-370. PubMed Central PMCID: 23453105. Full Text
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  - Khazanie P, Granger CB. A 10-year exercise program improved oxygen consumption and quality of life in stable chronic heart failure. ANNALS OF INTERNAL MEDICINE. 2013 Feb 19;158(4). PubMed PMID: 23420254. Full Text Link to Item
  - Fosbol EL, Granger CB, Jollis JG, Monk L, Lin L, Lytle BL, Xian Y, Garvey JL, Mears G, Corbett CC, Peterson ED, Glickman SW. The impact of a statewide pre-hospital STEMI strategy to bypass hospitals without percutaneous coronary intervention capability on treatment times. Circulation. 2013 Feb 5;127(5):604-612. PubMed PMID: 23275382. Full Text Link to Item
  - Huber K, Goldstein P, Danchin N, Fox KAA, Welsh R, Granger CB, Henry T, Gersh BJ. Enhancing the efficacy of delivering reperfusion therapy: a European and North American experience with ST-segment elevation myocardial infarction networks. Am Heart J. 2013 Feb;165(2):123-132. PubMed PMID: 23351814. (Review) Full Text Link to Item
  - Patel MR, Westerhout CM, Granger CB, Brener SJ, Fu Y, Siha H, Kim RJ, Armstrong PW. Aborted myocardial infarction after primary percutaneous coronary intervention: magnetic resonance imaging insights from the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) trial. Am Heart J. 2013 Feb;165(2):226-233. PubMed PMID: 23351826. Full Text Link to Item
  - Alexander JH, Levy E, Lawrence J, Hanna M, Waclawski AP, Wang J, Califf RM, Wallentin L, Granger CB. Documentation of study medication dispensing in a prospective large randomized clinical trial: Experiences from the ARISTOTLE Trial. American Heart Journal. 2013;166(3):559-565.e1. Full Text
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  - American College of Emergency Physicians , Society for Cardiovascular Angiography and Interventions , O'Gara PT, Kushner FG, Ascheim DD, Casey DE, Chung MK, de Lemos JA, Ettinger SM, Fang JC, Fesmire FM, Franklin BA, Granger CB, Krumholz HM, Linderbaum JA, Morrow DA, Newby LK, Ornato JP, Ou N, Radford MJ, Tamis-Holland JE, Tommaso CL, Tracy CM, Woo YJ, Zhao DX, Anderson JL, Jacobs AK, Halperin JL, Albert NM, Brindis RG, Creager MA, DeMets D, Guyton RA, Hochman JS, Kovacs RJ, Ohman EM, Stevenson WG, Yancy CW. 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Journal of the American College of Cardiology. 2013 Jan;61(4):485-510. PubMed Central PMCID: 23256913. Full Text
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  - Bagai A, Granger CB. Acute coronary syndromes: STREAMlining care for patients with STEMI. Nature Reviews Cardiology. 2013;10(6):304-306. Full Text
  - Bagai A, Jollis JG, Dauerman HL, Peng SA, Rokos IC, Bates ER, French WJ, Granger CB, Roe MT. Emergency department bypass for ST-segment-elevation myocardial infarction patients identified with a prehospital electrocardiogram: A report from the American heart association mission: Lifeline program. Circulation. 2013;128(4):352-359. Full Text
  - Bahit MC, Lopes RD, Clare RM, Newby LK, Pieper KS, Werf FVD, Armstrong PW, Mahaffey KW, Harrington RA, Diaz R, Ohman EM, White HD, James S, Granger CB. Heart failure complicating non-st-segment elevation acute coronary syndrome: Timing, predictors, and clinical outcomes. JACC: Heart Failure. 2013;1(3):223-229. PubMed PMID: 24621874. Full Text
  - Bahit MC, Lopes RD, Wojdyla DM, Hohnloser SH, Alexander JH, Lewis BS, Aylward PE, Verheugt FWA, Keltai M, Diaz R, Hanna M, Granger CB, Wallentin L. Apixaban in patients with atrial fibrillation and prior coronary artery disease: Insights from the ARISTOTLE trial. International Journal of Cardiology. 2013. PubMed PMID: 24192334.
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  - Desai J, Granger CB, Weitz JI, Aisenberg J. Novel oral anticoagulants in gastroenterology practice. Gastrointestinal Endoscopy. 2013;78(2):227-239. Full Text
  - Diepen SV, Newby LK, Lopes RD, Stebbins A, Hasselblad V, James S, Roe MT, Ezekowitz JA, Moliterno DJ, Neumann F-J, al E. Prognostic relevance of baseline pro- and anti-inflammatory markers in STEMI: An APEX AMI substudy. International Journal of Cardiology. 2013;168(3):2127-2133. Full Text
  - Diepen SV, Vavalle JP, Newby LK, Clare R, Pieper KS, Ezekowitz JA, Hochman JS, Mahaffey KW, Armstrong PW, Granger CB. The systemic inflammatory response syndrome in patients with ST-segment elevation myocardial infarction. Critical Care Medicine. 2013;41(9):2080-2087. Full Text
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  - Garcia DA, Wallentin L, Lopes RD, Thomas L, Alexander JH, Hylek EM, Ansell J, Hanna M, Lanas F, Flaker G, Commerford P, Xavier D, Vinereanu D, Yang H, Granger CB. Apixaban versus warfarin in patients with atrial fibrillation according to prior warfarin use: Results from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation trial. American Heart Journal. 2013;166(3):549-558. Full Text
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  - Henry TD, Jacobs AK, Granger CB. Regional systems of care for ST-elevation myocardial infarction: Do they save lives?. American Heart Journal. 2013. PubMed PMID: 24016484. Full Text
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  - Hijazi Z, Granger CB, Wallentin L. Reply: Higher N-terminal pro-B-type natriuretic peptide may be related to very different conditions. Journal of the American College of Cardiology. 2013;62(17):1635-1636. PubMed PMID: 23892249. Full Text
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  - Khazanie P, Granger CB. Commentary. Annals of Internal Medicine. 2013;158(4):JC6-.
  - Lopes RD, Becker RC, Newby LK, Peterson ED, Hylek EM, Giugliano R, Granger CB, Mahaffey KW, Carvalho AC, Berwanger O, Giraldez RR, Feitosa-Filho GS, Barbosa MM, Moreira MDCV, Kalil RAK, Freitas M, Guerra JCDC, Barros MVL, Rodrigues TDR, Lopes AC, Garcia DA. Highlights from the fifth international symposium of thrombosis and anticoagulation (ISTA V), october 18-19, 2012, Belo Horizonte, Minas Gerais, Brazil. Journal of Thrombosis and Thrombolysis. 2013;36(1):115-130. Full Text
  - Lopes RD, Lokhnygina Y, Hasselblad V, Newby KL, Yow E, Granger CB, Armstrong PW, Hochman JS, Mills JS, Ruzyllo W, Mahaffey KW. Methods of creatine kinase-MB analysis to predict mortality in patients with myocardial infarction treated with reperfusion therapy. Trials. 2013 Jan;14:123-null. PubMed Central PMCID: 23782531. Full Text Open Access Copy
  - Nicolau JC, Corbalan R, Diaz R, Bahit C, Armstrong PW, Granger CB, Lopes RD. Cardiovascular clinical research in South America. American Heart Journal. 2013. PubMed PMID: 23708154. Full Text
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  - Patel MR, Westerhout CM, Granger CB, Brener SJ, Fu Y, Siha H, Kim RJ, Armstrong PW. Aborted myocardial infarction after primary percutaneous coronary intervention: Magnetic resonance imaging insights from the assessment of pexelizumab in acute myocardial infarction (APEX-AMI) trial. American Heart Journal. 2013;165(2):226-233. Full Text
  - Kaul P, Fu Y, Westerhout CM, Granger CB, Armstrong PW. Relative prognostic value of baseline Q wave and time from symptom onset among men and women with ST-elevation myocardial infarction undergoing percutaneous coronary intervention. The American Journal of Cardiology. 2012 Dec;110(11):1555-1560. PubMed Central PMCID: 22920928. Full Text
  - Wang TY, Honeycutt EF, Tapson VF, Moll S, Granger CB, Ohman EM. Incidence of thrombocytopenia among patients receiving heparin venous thromboembolism prophylaxis. Am J Med. 2012 Dec;125(12):1214-1221. PubMed PMID: 22939359. Full Text Link to Item
  - Alherbish A, Westerhout CM, Fu Y, Granger CB, Armstrong PW. The Forgotten Lead: Does aVR ST-Deviation Add Insight into STEMI Patients?. CIRCULATION. 2012 Nov 20;126(21). Link to Item
  - Bagai A, Iollis JG, Dauerman HL, Peng SA, Bates ER, French WJ, Granger CB, Roe MT. Bypassing the Emergency Department is Associated with Faster Reperfusion in Patients with Pre-Hospital ST-Segment Elevation: Findings from the ACTION Registry (R)-GWTG (TM). CIRCULATION. 2012 Nov 20;126(21). Link to Item
  - Cecilia Bahit M, Lopes RD, Hohnloser SH, Wojdyla D, Alexander JH, Lewis BS, Aylward P, Verheugt FW, Keltai M, Diaz R, Mohan P, Granger CB, Wallentin L. Apixaban in Patients with Atrial Fibrillation and Prior Coronary Artery Disease: Insights from the ARISTOTLE Trial. CIRCULATION. 2012 Nov 20;126(21). Link to Item
  - Vavalle JP, van Diepen S, Lopes R, Clare R, Hochman JS, Weaver D, Mehta R, Pieper KS, Patel MR, Armstrong PW, Granger CB. Worse Renal Function is Associated with Markedly Worse Outcomes Among STEMI Patients Undergoing Primary PCI: Insights from the Assessment of Pexelizumab in Acute Myocardial Infarction ( APEX AMI) Trial. CIRCULATION. 2012 Nov 20;126(21). Link to Item
  - van Diepen S, Vavalle IP, Newby LK, Clare R, Pieper KS, Ezekowitz JA, Hochman JS, Mahaffey KW, Armstrong PW, Granger CB. The Systemic Inflammatory Response Syndrome is associated with Worse Outcomes in ST-Elevation Myocardial Infarction Patients: Insights from the CARDINAL Trial. CIRCULATION. 2012 Nov 20;126(21). Link to Item
  - Lopes RD, Al-Khatib SM, Wallentin L, Yang H, Ansell J, Bahit MC, De Caterina R, Dorian P, Easton JD, Erol C, Ezekowitz JA, Gersh BJ, Granger CB, Hohnloser SH, Horowitz J, Hylek EM, McMurray JJV, Mohan P, Vinereanu D, Alexander JH. Efficacy and safety of apixaban compared with warfarin according to patient risk of stroke and of bleeding in atrial fibrillation: a secondary analysis of a randomised controlled trial. Lancet. 2012 Nov 17;380(9855):1749-1758. PubMed PMID: 23036896. Full Text Link to Item
  - Hohnloser SH, Hijazi Z, Thomas L, Alexander JH, Amerena J, Hanna M, Keltai M, Lanas F, Lopes RD, Lopez-Sendon J, Granger CB, Wallentin L. Efficacy of apixaban when compared with warfarin in relation to renal function in patients with atrial fibrillation: insights from the ARISTOTLE trial. European Heart Journal. 2012 Nov;33(22):2821-2830. PubMed Central PMCID: 22933567. Full Text
  - Melloni C, Sprecher DL, Sarov-Blat L, Patel MR, Heitner JF, Hamm CW, Aylward P, Tanguay J-F, DeWinter RJ, Marber MS, Lerman A, Hasselblad V, Granger CB, Newby LK. The study of LoSmapimod treatment on inflammation and InfarCtSizE (SOLSTICE): design and rationale. Am Heart J. 2012 Nov;164(5):646-653.e3. PubMed PMID: 23137494. Full Text Link to Item
  - Vavalle JP, Lopes RD, Chen AY, Newby LK, Wang TY, Shah BR, Ho PM, Wiviott SD, Peterson ED, Roe MT, Granger CB. Hospital length of stay in patients with non-ST-segment elevation myocardial infarction. Am J Med. 2012 Nov;125(11):1085-1094. PubMed PMID: 22921886. Full Text Link to Item
  - Hess CN, Broderick S, Piccini JP, Alexander KP, Newby LK, Shaw LK, Mahaffey KW, Alexander JH, Peterson ED, Granger CB, Lopes RD. Antithrombotic therapy for atrial fibrillation and coronary artery disease in older patients. Am Heart J. 2012 Oct;164(4):607-615. PubMed PMID: 23067921. Full Text Link to Item
  - Ciervo CA, Granger CB, Schaller FA, Engelke KA. A new era of anticoagulation treatment: optimizing outcomes for atrial fibrillation. The Journal of the American Osteopathic Association. 2012 Sep;112(9 Suppl 2):eS9-e21. PubMed PMID: 23014815.
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  - Johnson RW, Zhao Y, Newby LK, Granger CB, Granger BB. Reasons for noncompletion of advance directives in a cardiac intensive care unit. Am J Crit Care. 2012 Sep;21(5):311-320. PubMed PMID: 22941703. Full Text Link to Item
  - Lopes RD, Li L, Granger CB, Wang TY, Foody JM, Funk M, Peterson ED, Alexander KP. Atrial fibrillation and acute myocardial infarction: antithrombotic therapy and outcomes. Am J Med. 2012 Sep;125(9):897-905. PubMed PMID: 22795814. Full Text Link to Item
  - Morrow DA, Fang JC, Fintel DJ, Granger CB, Katz JN, Kushner FG, Kuvin JT, Lopez-Sendon J, McAreavey D, Nallamothu B, Page RL, Parrillo JE, Peterson PN, Winkelman C, American Heart Association Council on Cardiopulmonary Critical Care Perioperative and Resuscitation Council on Clinical Cardiology Council on Cardiovascular Nursing and Council on Quality of Care and Outcomes Research . Evolution of critical care cardiology: transformation of the cardiovascular intensive care unit and the emerging need for new medical staffing and training models: a scientific statement from the American Heart Association. Circulation. 2012 Sep;126(11):1408-1428. PubMed Central PMCID: 22893607. Full Text
  - Yancy CW, Granger CB, Nichol G. Systems of health care. 2012 Sep 1:67-74. (Chapter) Full Text
  - van Diepen S, Newby L, Lopes R, Stebbins A, Hasselblad V, James S, Roe M, Ezekowitz J, Moliterno D, Neumann F, Reist C, Hochman J, Mahaffey K, Hamm C, Armstrong P, Granger C, Theroux P. 726 Acute Phase Inflammatory Biomarkers Add Little Predictive Value to Clinical Factors Plus NT-proBNP Among Patients With ST-Segment Elevation Myocardial Infarction: An Apex AMI Trial Substudy. Canadian Journal of Cardiology. 2012 Sep;28(5):S378-S378. Full Text
  - Muñoz D, Roettig ML, Monk L, Al-Khalidi H, Jollis JG, Granger CB. Transport time and care processes for patients transferred with ST-segment-elevation myocardial infarction: the reperfusion in acute myocardial infarction in Carolina emergency rooms experience. Circ Cardiovasc Interv. 2012 Aug 1;5(4):555-562. PubMed PMID: 22872054. Full Text Link to Item
  - Jollis JG, Al-Khalidi HR, Monk L, Roettig ML, Garvey JL, Aluko AO, Wilson BH, Applegate RJ, Mears G, Corbett CC, Granger CB, Regional Approach to Cardiovascular Emergencies (RACE) Investigators . Expansion of a regional ST-segment-elevation myocardial infarction system to an entire state. Circulation. 2012 Jul 10;126(2):189-195. PubMed PMID: 22665718. Full Text Link to Item
  - Jollis JG, Granger CB, Henry TD, Antman EM, Berger PB, Moyer PH, Pratt FD, Rokos IC, Acuña AR, Roettig ML, Jacobs AK. Systems of care for ST-segment-elevation myocardial infarction: a report From the American Heart Association's Mission: Lifeline. Circ Cardiovasc Qual Outcomes. 2012 Jul 1;5(4):423-428. PubMed PMID: 22619274. Full Text Link to Item
  - Lopes RD, Becker RC, Newby LK, Peterson ED, Hylek EM, Granger CB, Crowther M, Wang T, Carvalho AC, Berwanger O, Giraldez RR, Feitosa GS, Ribeiro JP, Darze E, Kalil RAK, Andrande M, Boas FV, Andrade J, Rocha AT, Harrington RA, Lopes AC, Garcia DA. Highlights from the IV International Symposium of Thrombosis and Anticoagulation (ISTA), October 20-21, 2011, Salvador, Bahia, Brazil. J Thromb Thrombolysis. 2012 Jul;34(1):143-163. PubMed PMID: 22427055. Full Text Link to Item
  - Meta-analysis Global Group in Chronic Heart Failure (MAGGIC) . The survival of patients with heart failure with preserved or reduced left ventricular ejection fraction: an individual patient data meta-analysis. European Heart Journal. 2012 Jul;33(14):1750-1757. PubMed Central PMCID: 21821849. (Review) Full Text
  - Truffa AAM, Granger CB, White KR, Newby LK, Mehta RH, Hochman JS, Patel MR, Pieper KS, Al-Khalidi HR, Armstrong PW, Lopes RD. Serious infection after acute myocardial infarction: incidence, clinical features, and outcomes. JACC Cardiovasc Interv. 2012 Jul;5(7):769-776. PubMed PMID: 22814783. Full Text Link to Item
  - van Diepen S, Roe MT, Lopes RD, Stebbins A, James S, Newby LK, Moliterno DJ, Neumann F-J, Ezekowitz JA, Mahaffey KW, Hochman JS, Hamm CW, Armstrong PW, Theroux P, Granger CB. Baseline NT-proBNP and biomarkers of inflammation and necrosis in patients with ST-segment elevation myocardial infarction: insights from the APEX-AMI trial. J Thromb Thrombolysis. 2012 Jul;34(1):106-113. PubMed PMID: 22307842. Full Text Link to Item
  - van Diepen S, Widimsky P, Lopes RD, White KR, Weaver WD, Van de Werf F, Ardissino D, van't Hof AWJ, Armstrong PW, Granger CB. Transfer times and outcomes in patients with ST-segment-elevation myocardial infarction undergoing interhospital transfer for primary percutaneous coronary intervention: APEX-AMI insights. Circ Cardiovasc Qual Outcomes. 2012 Jul 1;5(4):437-444. PubMed PMID: 22589297. Full Text Link to Item
  - Easton JD, Lopes RD, Bahit MC, Wojdyla DM, Granger CB, Wallentin L, Alings M, Goto S, Lewis BS, Rosenqvist M, Hanna M, Mohan P, Alexander JH, Diener H-C, ARISTOTLE Committees and Investigators . Apixaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of the ARISTOTLE trial. The Lancet. Neurology. 2012 Jun;11(6):503-511. PubMed Central PMCID: 22572202. Full Text
  - Steinberg BA, Jollis JG, Winkler A, Granger C, Newby LK. Treatment pathways and quality improvement for patients with acute myocardial infarction at a tertiary care center. Crit Pathw Cardiol. 2012 Jun;11(2):77-80. PubMed PMID: 22595818. Full Text Link to Item
  - Wiggins NB, Granger CB, Alexander JH. Novel oral anticoagulants after acute coronary syndromes. Cardiovasc Drugs Ther. 2012 Jun;26(3):265-271. PubMed PMID: 22434545. (Review) Full Text Link to Item
  - Zeymer U, Huber K, Fu Y, Ross A, Granger C, Goldstein P, van de Werf F, Armstrong P. Impact of TIMI 3 patency before primary percutaneous coronary intervention for ST-elevation myocardial infarction on clinical outcome: results from the ASSENT-4 PCI study. European Heart Journal: Acute Cardiovascular Care. 2012 Jun;1(2):136-142. Full Text
  - Castagno D, Skali H, Takeuchi M, Swedberg K, Yusuf S, Granger CB, Michelson EL, Pfeffer MA, McMurray JJV, Solomon SD, CHARM Investigators . Association of heart rate and outcomes in a broad spectrum of patients with chronic heart failure: results from the CHARM (Candesartan in Heart Failure: Assessment of Reduction in Mortality and morbidity) program. Journal of the American College of Cardiology. 2012 May;59(20):1785-1795. PubMed Central PMCID: 22575317. Full Text
  - Mehta RH, Kaul P, Lopes RD, Patel MR, Zheng Y, Pieper KS, Welsh RC, Armstrong PW, Granger CB. Variations in practice and outcomes in patients undergoing primary percutaneous coronary intervention in the United States and Canada: insights from the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX AMI) trial. American Heart Journal. 2012 May;163(5):797-803. PubMed Central PMCID: 22607857. Full Text
  - Shah SH, Sun J-L, Stevens RD, Bain JR, Muehlbauer MJ, Pieper KS, Haynes C, Hauser ER, Kraus WE, Granger CB, Newgard CB, Califf RM, Newby LK. Baseline metabolomic profiles predict cardiovascular events in patients at risk for coronary artery disease. American Heart Journal. 2012 May;163(5):844-850.e1. PubMed Central PMCID: 22607863. Full Text
  - van Diepen S, Granger CB. Acute coronary syndromes. Challenging accepted post-MI serum potassium targets. Nature Reviews. Cardiology. 2012 May;9(5):259-260. PubMed Central PMCID: 22371108. Full Text
  - Munoz D, Granger CB. Review: Statins reduce mortality and cardiovascular (CV) morbidity in patients with low CV risk. ANNALS OF INTERNAL MEDICINE. 2012 Apr 17;156(8). PubMed PMID: 22508747. Full Text Link to Item
  - Davies RW, Wells GA, Stewart AFR, Erdmann J, Shah SH, Ferguson JF, Hall AS, Anand SS, Burnett MS, Epstein SE, Dandona S, Chen L, Nahrstaedt J, Loley C, König IR, Kraus WE, Granger CB, Engert JC, Hengstenberg C, Wichmann H-E, Schreiber S, Tang WHW, Ellis SG, Rader DJ, Hazen SL, Reilly MP, Samani NJ, Schunkert H, Roberts R, McPherson R. A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex. Circulation. Cardiovascular Genetics. 2012 Apr;5(2):217-225. PubMed Central PMCID: 22319020. Full Text
  - Glickman SW, Greiner MA, Lin L, Curtis LH, Cairns CB, Granger CB, Peterson ED. Assessment of temporal trends in mortality with implementation of a statewide ST-segment elevation myocardial infarction (STEMI) regionalization program. Ann Emerg Med. 2012 Apr;59(4):243-252.e1. PubMed PMID: 21862177. Full Text Link to Item
  - Shah AA, Craig DM, Sebek JK, Haynes C, Stevens RC, Muehlbauer MJ, Granger CB, Hauser ER, Newby LK, Newgard CB, Kraus WE, Hughes GC, Shah SH. Metabolic profiles predict adverse events after coronary artery bypass grafting. The Journal of Thoracic and Cardiovascular Surgery. 2012 Apr;143(4):873-878. PubMed Central PMCID: 22306227. Full Text
  - Glickman SW, Shofer FS, Wu MC, Scholer MJ, Ndubuizu A, Peterson ED, Granger CB, Cairns CB, Glickman LT. Development and validation of a prioritization rule for obtaining an immediate 12-lead electrocardiogram in the emergency department to identify ST-elevation myocardial infarction. Am Heart J. 2012 Mar;163(3):372-382. PubMed PMID: 22424007. Full Text Link to Item
  - Mills JS, Mahaffey KW, Lokhnygina Y, Nicolau JC, Ruzyllo W, Adams PX, Todaro TG, Armstrong PW, Granger CB, CARDINAL investigators . Prediction of enzymatic infarct size in ST-segment elevation myocardial infarction. Coronary Artery Disease. 2012 Mar;23(2):118-125. PubMed Central PMCID: 22217457. Full Text
  - Nolan DK, Sutton B, Haynes C, Johnson J, Sebek J, Dowdy E, Crosslin D, Crossman D, Sketch MH, Granger CB, Seo D, Goldschmidt-Clermont P, Kraus WE, Gregory SG, Hauser ER, Shah SH. Fine mapping of a linkage peak with integration of lipid traits identifies novel coronary artery disease genes on chromosome 5. (Published online) BMC Genet. 2012 Feb 27;13:12-. PubMed PMID: 22369142. Full Text Link to Item
  - Al-Khatib SM, Alexander JH, Lopes RD, Mahaffey KW, Patel MR, Granger CB. Promise of factor Xa inhibition in atrial fibrillation. Curr Cardiol Rep. 2012 Feb;14(1):70-78. PubMed PMID: 22109539. (Review) Full Text Link to Item
  - Mehta RH, Stebbins AS, Lopes RD, Califf RM, Pieper KS, Armstrong PW, Van de Werf F, Hochman JS, White HD, Topol EJ, Alexander JH, Granger CB. Comparison of incidence of bleeding and mortality of men versus women with ST-elevation myocardial infarction treated with fibrinolysis. The American Journal of Cardiology. 2012 Feb;109(3):320-326. PubMed Central PMCID: 22078221. Full Text
  - Hernandez AF, Granger CB. Prediction is very hard, especially about the future: comment on "factors associated with 30-day readmission rates after percutaneous coronary intervention". Arch Intern Med. 2012 Jan 23;172(2):117-119. PubMed PMID: 22123750. Full Text Link to Item
  - Garvey JL, Monk L, Granger CB, Studnek JR, Roettig ML, Corbett CC, Jollis JG. Rates of cardiac catheterization cancelation for ST-segment elevation myocardial infarction after activation by emergency medical services or emergency physicians: results from the North Carolina Catheterization Laboratory Activation Registry. Circulation. 2012 Jan 17;125(2):308-313. PubMed PMID: 22147904. Full Text Link to Item
  - Granger CB, Hanna M, Wallentin L. Apixaban versus Warfarin in Atrial Fibrillation REPLY. NEW ENGLAND JOURNAL OF MEDICINE. 2012 Jan 5;366(1):89-89. Link to Item
  - Bagai A, Granger CB. Regionalization of ST-segment elevation myocardial infarction care: A task unfinished. American Heart Journal. 2012;164(5):633-635. PubMed PMID: 23137491. Full Text
  - Diener H-C, Eikelboom J, Granger CB, Hacke W. The king is dead (warfarin): Direct thrombin and factor Xa inhibitors: The next Diadochian War?. International Journal of Stroke. 2012;7(2):139-141. PubMed PMID: 22264366. Full Text
  - Garcia DA, Granger CB. Anticoagulation, novel agents, and procedures: Can we pardon the interruption?. Circulation. 2012;126(3):255-257. PubMed PMID: 22700855. Full Text
  - Granger CB, Armaganijan LV. Newer oral anticoagulants should be used as first-line agents to prevent thromboembolism in patients with atrial fibrillation and risk factors for stroke or thromboembolism. Circulation. 2012 Jan;125(1):159-164. PubMed Central PMCID: 22215890. (Review) Full Text
  - Granger CB, Hanna M, Wallentin L. The authors reply. New England Journal of Medicine. 2012;366(1):89--.
  - Granger CB. Apixaban reduced stroke and systemic embolism compared with warfarin in atrial fibrillation. Annals of Internal Medicine. 2012;156(2). Full Text
  - Guzman LA, Li S, Wang TY, Daviglus ML, Exaire J, Rodriguez CJ, Torres VI, Funk M, Saucedo J, Granger C, Pia IL, Cohen MG. Differences in treatment patterns and outcomes between hispanics and non-hispanic whites treated for ST-segment elevation myocardial infarction: Results from the NCDR ACTION registry-GWTG. Journal of the American College of Cardiology. 2012;59(6):630-631. PubMed PMID: 22300700. Full Text
  - Kociol RD, Lopes RD, Clare R, Thomas L, Mehta RH, Kaul P, Pieper KS, Hochman JS, Weaver WD, Armstrong PW, Granger CB, Patel MR. International variation in and factors associated with hospital readmission after myocardial infarction. Jama. 2012 Jan;307(1):66-74. PubMed Central PMCID: 22215167. Full Text
  - Lofthus DM, Stevens SR, Armstrong PW, Granger CB, Mahaffey KW. Pattern of liver enzyme elevations in acute ST-elevation myocardial infarction. Coron Artery Dis. 2012 Jan;23(1):22-30. PubMed PMID: 22113063. Full Text Link to Item
  - Martel C, Granger CB, Ghitescu M, Stebbins A, Fortier A, Armstrong PW, Bonnefoy A, Theroux P. Pexelizumab fails to inhibit assembly of the terminal complement complex in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Insight from a substudy of the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) trial. American Heart Journal. 2012;164(1):43-51. PubMed PMID: 22795281. Full Text
  - Morrow DA, Fang JC, Fintel DJ, Granger CB, Katz JN, Kushner FG, Kuvin JT, Lopez-Sendon J, McAreavey D, Nallamothu B, 2nd RLP, Parrillo JE, Peterson PN, Winkelman C, Cardiopulmonary AHACO, Clinical CCPARCO, Quality CCOCNACO, Research OCAO. Evolution of critical care cardiology: transformation of the cardiovascular intensive care unit and the emerging need for new medical staffing and training models: a scientific statement from the American Heart Association. Circulation. 2012;126(11):1408-1428.
  - Turakhia MP, Estes NAM, Drew BJ, Granger CB, Wang PJ, Knight BP, Page RL. Latency of ECG displays of hospital telemetry systems: A science advisory from the American heart association. Circulation. 2012;126(13):1665-1669. PubMed PMID: 22927339. Full Text
  - Werf FVD, Brueckmann M, Connolly SJ, Friedman J, Granger CB, Härtter S, Harper R, Kappetein AP, Lehr T, Mack MJ, Noack H, Eikelboom JW. A comparison of dabigatran etexilate with warfarin in patients with mechanical heart valves: The Randomized, phase II study to Evaluate the sAfety and pharmacokinetics of oraL dabIGatran etexilate in patients after heart valve replacemeNt (RE-ALIGN). American Heart Journal. 2012;163(6):931-937.e1. PubMed PMID: 22709744. Full Text
  - Werf FVD, Connolly SJ, Kappetein AP, Brueckmann M, MacK MJ, Granger CB, Eikelboom J. Letter by Van de Werf et al regarding article, "using dabigatran in patients with stroke: A practical guide for clinicians". Stroke. 2012;43(5):e46-e47. PubMed PMID: 22461333. Full Text
  - Wang TY, Granger CB. ACP Journal Club. Review: Reduced function CYP2C19 genotypes may increase risk for stent clots in patients receiving clopidogrel. Ann Intern Med. 2011 Dec 20;155(12):JC6-J13. PubMed PMID: 22184714. Full Text Link to Item
  - Brunner MP, Shah SH, Craig DM, Stevens RD, Muehlbauer MJ, Bain JR, Newgard CB, Kraus WE, Granger CB, Sketch MH, Newby LK. Effect of heparin administration on metabolomic profiles in samples obtained during cardiac catheterization. Circulation. Cardiovascular Genetics. 2011 Dec;4(6):695-700. PubMed Central PMCID: 22010138. Full Text
  - Connolly SJ, Camm AJ, Halperin JL, Joyner C, Alings M, Amerena J, Atar D, Avezum Á, Blomström P, Borggrefe M, Budaj A, Chen S-A, Ching CK, Commerford P, Dans A, Davy J-M, Delacrétaz E, Di Pasquale G, Diaz R, Dorian P, Flaker G, Golitsyn S, Gonzalez-Hermosillo A, Granger CB, Heidbüchel H, Kautzner J, Kim JS, Lanas F, Lewis BS, Merino JL, Morillo C, Murin J, Narasimhan C, Paolasso E, Parkhomenko A, Peters NS, Sim K-H, Stiles MK, Tanomsup S, Toivonen L, Tomcsányi J, Torp-Pedersen C, Tse H-F, Vardas P, Vinereanu D, Xavier D, Zhu J, Zhu J-R, Baret-Cormel L, Weinling E, Staiger C, Yusuf S, Chrolavicius S, Afzal R, Hohnloser SH, PALLAS Investigators . Dronedarone in high-risk permanent atrial fibrillation. The New England Journal of Medicine. 2011 Dec;365(24):2268-2276. PubMed Central PMCID: 22082198. Full Text
  - Bhattacharya S, Craig D, Haynes C, Granger CB, Stevens RD, Hauser ER, Kraus WE, Newgard CB, Newby LK, Shah SH. Peripheral Metabolite Profiles Discriminate Coronary Artery Disease in a Sequential Cohort of Cardiac Catheterization Patients. CIRCULATION. 2011 Nov 22;124(21). Link to Item
  - Cecilia Bahit M, Lopes RD, Clare R, Pieper KS, Newby LK, Van de Werf FF, Armstrong PW, Mahaffey KW, Harrington RA, Ohman EM, Diaz R, White HD, Hernandez AF, Wallentin L, Califf RM, Granger CB. Heart Failure Occurring at any Time During Hospitalization is Associated with Higher Mortality in Non-ST Elevation-Acute Coronary Syndromes. CIRCULATION. 2011 Nov 22;124(21). Link to Item
  - Guptill JT, Lopes RD, Mehta RH, Horton J, Laskowitz D, Pieper KS, Armstrong PW, Granger CB. Most Strokes Occur More Than 48 Hours Following Primary Percutaneous Coronary Intervention in STEMI: the Stroke Experience in APEX-AMI Trial. CIRCULATION. 2011 Nov 22;124(21). Link to Item
  - Ariti CA, Cleland JGF, Pocock SJ, Pfeffer MA, Swedberg K, Granger CB, McMurray JJV, Michelson EL, Ostergren J, Yusuf S. Days alive and out of hospital and the patient journey in patients with heart failure: Insights from the candesartan in heart failure: assessment of reduction in mortality and morbidity (CHARM) program. American Heart Journal. 2011 Nov;162(5):900-906. PubMed Central PMCID: 22093207. Full Text
  - Oldgren J, Budaj A, Granger CB, Khder Y, Roberts J, Siegbahn A, Tijssen JGP, Van de Werf F, Wallentin L, RE-DEEM Investigators . Dabigatran vs. placebo in patients with acute coronary syndromes on dual antiplatelet therapy: a randomized, double-blind, phase II trial. European Heart Journal. 2011 Nov;32(22):2781-2789. PubMed Central PMCID: 21551462. Full Text
  - Lopes RD, Siha H, Fu Y, Mehta RH, Patel MR, Armstrong PW, Granger CB. Diagnosing acute myocardial infarction in patients with left bundle branch block. Am J Cardiol. 2011 Sep 15;108(6):782-788. PubMed PMID: 21726838. Full Text Link to Item
  - Bosworth HB, Granger BB, Mendys P, Brindis R, Burkholder R, Czajkowski SM, Daniel JG, Ekman I, Ho M, Johnson M, Kimmel SE, Liu LZ, Musaus J, Shrank WH, Whalley Buono E, Weiss K, Granger CB. Medication adherence: a call for action. American Heart Journal. 2011 Sep;162(3):412-424. PubMed Central PMCID: 21884856. (Review) Full Text
  - Granger CB, Alexander JH, McMurray JJV, Lopes RD, Hylek EM, Hanna M, Al-Khalidi HR, Ansell J, Atar D, Avezum A, Bahit MC, Diaz R, Easton JD, Ezekowitz JA, Flaker G, Garcia D, Geraldes M, Gersh BJ, Golitsyn S, Goto S, Hermosillo AG, Hohnloser SH, Horowitz J, Mohan P, Jansky P, Lewis BS, Lopez-Sendon JL, Pais P, Parkhomenko A, Verheugt FWA, Zhu J, Wallentin L, ARISTOTLE Committees and Investigators . Apixaban versus warfarin in patients with atrial fibrillation. The New England Journal of Medicine. 2011 Sep;365(11):981-992. PubMed Central PMCID: 21870978. Full Text
  - Fosbol EL, Granger CB. ACP Journal Club. Meta-analysis: high-dose statin pretreatment prevents periprocedural cardiac events in patients having PCI. Ann Intern Med. 2011 Aug 16;155(4):JC2-JC8. PubMed PMID: 21844541. Full Text Link to Item
  - Vavalle JP, Granger CB. The need for regional integrated care for ST-segment elevation myocardial infarction. Circulation. 2011 Aug 16;124(7):851-856. PubMed PMID: 21844091. Full Text Link to Item
  - Chan MY, Shah BR, Gao F, Sim LL, Chua T, Tan HC, Yeo TC, Ong HY, Foo D, Goh PP, Surrun SK, Pieper KS, Granger CB, Koh TH, Salim A, Tai ES. Recalibration of the Global Registry of Acute Coronary Events risk score in a multiethnic Asian population. American Heart Journal. 2011 Aug;162(2):291-299. PubMed Central PMCID: 21835290. Full Text
  - Lopes RD, Becker RC, Alexander JH, Armstrong PW, Califf RM, Chan MY, Crowther M, Granger CB, Harrington RA, Hylek EM, James SK, Jolicoeur EM, Mahaffey KW, Newby LK, Peterson ED, Pieper KS, Van de Werf F, Wallentin L, White HD, Carvalho AC, Giraldez RR, Guimaraes HP, Nader HB, Kalil RAK, Bizzachi JMA, Lopes AC, Garcia DA. Highlights from the III International Symposium of Thrombosis and Anticoagulation (ISTA), October 14-16, 2010, São Paulo, Brazil. Journal of Thrombosis and Thrombolysis. 2011 Aug;32(2):242-266. PubMed Central PMCID: 21547405. Full Text
  - Mehta RH, Kaul P, Lopes RD, Patel MR, Pieper KS, Armstrong PW, Granger CB. Variations in practice and outcomes in patients undergoing primary percutaneous coronary intervention in the United States and Canada: insights from the APEX-AMI trial. EUROPEAN HEART JOURNAL. 2011 Aug;32:872-872. Link to Item
  - Mehta RH, Stebbins A, Lopes RD, Califf RM, Alexander JH, Granger CB. Gender paradox: higher incidence but lower one-year mortality with bleeding among women compared with men following fibrinolysis for acute ST-elevation myocardial infarction. EUROPEAN HEART JOURNAL. 2011 Aug;32:166-166. Link to Item
  - French JK, Armstrong PW, Cohen E, Kleiman NS, O'Connor CM, Hellkamp AS, Stebbins A, Holmes DR, Hochman JS, Granger CB, Mahaffey KW. Cardiogenic shock and heart failure post-percutaneous coronary intervention in ST-elevation myocardial infarction: observations from "Assessment of Pexelizumab in Acute Myocardial Infarction". Am Heart J. 2011 Jul;162(1):89-97. PubMed PMID: 21742094. Full Text Link to Item
  - Glickman SW, Lytle BL, Ou F-S, Mears G, O'Brien S, Cairns CB, Garvey JL, Bohle DJ, Peterson ED, Jollis JG, Granger CB. Care processes associated with quicker door-in-door-out times for patients with ST-elevation-myocardial infarction requiring transfer: results from a statewide regionalization program. Circulation. Cardiovascular Quality and Outcomes. 2011 Jul;4(4):382-388. PubMed Central PMCID: 21712523. Full Text
  - Gersh BJ, Freedman JE, Granger CB. [Antiplatelet and anticoagulant therapy for stroke prevention in patients with non-valvular atrial fibrillation: evidence based strategies and new developments]. Rev Esp Cardiol. 2011 Apr;64(4):260-268. PubMed PMID: 21411211. (Review) Full Text Link to Item
  - Gersh BJ, Freedman JE, Granger CB. Antiplatelet and Anticoagulant Therapy for Stroke Prevention in Patients With Non-Valvular Atrial Fibrillation: Evidence Based Strategies and New Developments. REVISTA ESPANOLA DE CARDIOLOGIA. 2011 Apr;64(4):260-268. PubMed PMID: 24775187. Full Text Link to Item
  - Gersh BJ, Freedman JE, Granger CB. Antiplatelet and anticoagulant therapy for stroke prevention in patients with non-valvular atrial fibrillation: Evidence based strategies and new developments. Revista Espanola de Cardiologia. 2011 Apr 1;64(4):260-268. Full Text
  - Mehta RH, Starr AZ, Lopes RD, Piccini JP, Patel MR, Pieper KS, Armstrong PW, Granger CB. Relationship of sustained ventricular tachyarrhythmias to outcomes in patients undergoing primary percutaneous coronary intervention with varying underlying baseline risk. Am Heart J. 2011 Apr;161(4):782-789. PubMed PMID: 21473979. Full Text Link to Item
  - Teo KK, Sleight P, Gao P, Yusuf S, Connolly S, Yusuf S, Swedberg K, Pfeffer MA, Granger CB, McMurray JJV, Sjoelie AK, Massie BM, Carson P, Lewis JB, Wachtell K, Dahlof B, Devereux RB, Kjeldsen SE, Julius S, Ibsen H, Lindholm LH, Olsen MH, Okin PM, Califf R, Holman RR, Haffner SM, Dagenais G, Probstfield J, Anderson C, Diaz R, Dans A, Levine M, Unger T, Fagard R, Diener H-C, Sacco RL, Zanchetti A, Cohn JN, Weber M, Collaboration ARBT. Effects of telmisartan, irbesartan, valsartan, candesartan, and losartan on cancers in 15 trials enrolling 138 769 individuals The ARB Trialists Collaboration. JOURNAL OF HYPERTENSION. 2011 Apr;29(4):623-635. Full Text Link to Item
  - Gharacholou SM, Lopes RD, Alexander KP, Mehta RH, Stebbins AL, Pieper KS, James SK, Armstrong PW, Granger CB. Age and outcomes in ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention: findings from the APEX-AMI trial. Archives of Internal Medicine. 2011 Mar;171(6):559-567. PubMed Central PMCID: 21444846. Full Text
  - Mahaffey KW, Wampole JL, Stebbins A, Berdan LG, McAfee D, Rorick TL, French JK, Kleiman NS, O'Connor CM, Cohen EA, Granger CB, Armstrong PW, APEX-AMI Investigators . Strategic lessons from the clinical event classification process for the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) trial. Contemporary Clinical Trials. 2011 Mar;32(2):178-187. PubMed Central PMCID: 21220052. Full Text
  - de Boer SPM, Barnes EH, Westerhout CM, Simes RJ, Granger CB, Kastrati A, Widimsky P, de Boer MJ, Zijlstra F, Boersma E. High-risk patients with ST-elevation myocardial infarction derive greatest absolute benefit from primary percutaneous coronary intervention: results from the Primary Coronary Angioplasty Trialist versus thrombolysis (PCAT)-2 collaboration. American Heart Journal. 2011 Mar;161(3):500-507.e1. PubMed Central PMCID: 21392604. Full Text
  - Granger CB. Who should have a routine early invasive approach after fibrinolytic therapy?. European Heart Journal. 2011;32(16):1961-1963. PubMed PMID: 21447512. Full Text
  - Holmes DR, Becker JA, Granger CB, Limacher MC, Page RL, Sila C. ACCF/AHA 2011 health policy statement on therapeutic interchange and substitution: A report of the american college of cardiology foundation clinical quality committee. Circulation. 2011;124(11):1290-1310. PubMed PMID: 21844072. Full Text
  - Hudson MP, Armstrong PW, O'Neil WW, Stebbins AL, Douglas WW, Widimsky P, Aylward PE, Ruzyllo W, Holmes D, Mahaffey KW, Granger CB. Mortality implications of primary percutaneous coronary intervention treatment delays: Insights from the assessment of pexelizumab in acute myocardial infarction trial. Circulation: Cardiovascular Quality and Outcomes. 2011;4(2):183-192. PubMed PMID: 21304097. Full Text
  - Jr DRH, Becker JA, Granger CB, Limacher MC, II RLP, Sila C, Jr JPD, Cacchione JG, Jr BDE, Harrington RA, Kennett JD, Krumholz HM, Masoudi FA, Peterson ED, Poppas A, Sahn DJ, Sanz ML, Shahian DM, Windle JR, Wyman JF. ACCF/AHA 2011 health policy statement on therapeutic interchange and substitution: A report of the american college of cardiology foundation clinical quality committee. Journal of the American College of Cardiology. 2011;58(12):1287-1307. PubMed PMID: 21849242. Full Text
  - Mayer SA, Kurtz P, Wyman A, Sung GY, Multz AS, Varon J, Granger CB, Kleinschmidt K, Lapointe M, Peacock WF, Katz JN, Gore JM, Oneil B, Anderson FA. Clinical practices, complications, and mortality in neurological patients with acute severe hypertension: The Studying the Treatment of Acute hyperTension registry. Critical Care Medicine. 2011;39(10):2330-2336. PubMed PMID: 21666448. Full Text
  - Mehta RH, O'Shea JC, Stebbins AL, Granger CB, Armstrong PW, White HD, Topol EJ, Califf RM, Ohman EM. Association of mortality with years of education in patients with ST-segment elevation myocardial infarction treated with fibrinolysis. Journal of the American College of Cardiology. 2011 Jan;57(2):138-146. PubMed Central PMCID: 21211684. Full Text
  - Mehta RH, Stebbins A, Lopes RD, Rao SV, Bates ER, Pieper KS, Armstrong PW, Van de Werf F, White HD, Califf RM, Alexander JH, Granger CB. Race, Bleeding, and Outcomes in STEMI Patients Treated with Fibrinolytic Therapy. The American Journal of Medicine. 2011 Jan;124(1):48-57. PubMed Central PMCID: 21187185. Full Text
  - Muñoz D, Granger CB. ST-segment-elevation myocardial infarction treatment and the seductive lure of observational analyses. Circulation. 2011;124(23):2477-2479. PubMed PMID: 22144629. Full Text
  - Peacock F, Amin A, Granger CB, Pollack CV, Levy P, Nowak R, Kleinschmidt K, Varon J, Wyman A, Gore JM. Hypertensive heart failure: Patient characteristics, treatment, and outcomes. American Journal of Emergency Medicine. 2011;29(8):855-862. PubMed PMID: 20825913. Full Text
  - Piccini JP, Schulte PJ, Pieper KS, Mehta RH, White HD, Van de Werf F, Ardissino D, Califf RM, Granger CB, Ohman EM, Alexander JH. Antiarrhythmic drug therapy for sustained ventricular arrhythmias complicating acute myocardial infarction. Critical Care Medicine. 2011 Jan;39(1):78-83. PubMed Central PMCID: 20959785. Full Text
  - Ranasinghe I, Alprandi-Costa B, Chow V, Elliott JM, Waites J, Counsell JT, Lopéz-Sendón J, Avezum Á, Goodman SG, Granger CB, Brieger D. Risk stratification in the setting of non-ST elevation acute coronary syndromes 1999-2007. American Journal of Cardiology. 2011;108(5):617-624. PubMed PMID: 21714948. Full Text
  - Steg PG, Mehta SR, Jukema JW, Lip GYH, Gibson CM, Kovar F, Kala P, Garcia-Hernandez A, Renfurm RW, Granger CB. RUBY-1: A randomized, double-blind, placebo-controlled trial of the safety and tolerability of the novel oral factor Xa inhibitor darexaban (YM150) following acute coronary syndrome. European Heart Journal. 2011;32(20):2541-2554. PubMed PMID: 21878434. Full Text
  - Szczech LA, Granger CB, Katz JN, Dasta JF, Amin A, Peacock WF, McCullough PA, Devlin JW, Weir MR, Wyman A, Anderson FA, Varon J. Response to letter regarding article, acute kidney injury and cardiovascular outcomes in acute severe hypertension. Circulation. 2011;123(9):e268-. Full Text
  - Vuylsteke A, Vincent J-L, de La Garanderie DP, Anderson FA, Emery L, Wyman A, Rushton-Smith S, Gore JM, Euro-STAT Investigators . Characteristics, practice patterns, and outcomes in patients with acute hypertension: European registry for Studying the Treatment of Acute hyperTension (Euro-STAT). Critical care (London, England). 2011 Jan;15(6):R271-. PubMed PMID: 22087790. Full Text
  - Wang TY, Granger CB. Review: Reduced function CYP2C19 genotypes may increase risk for stent clots in patients receiving clopidogrel. Annals of Internal Medicine. 2011;155(12):JC6-J13.
  - Weed J, Finkel K, Beach ML, Granger CB, Gallagher JD, Sites BD. Spinal anesthesia for orthopedic surgery: a detailed video assessment of quality. Regional anesthesia and pain medicine. 2011 Jan;36(1):51-55. PubMed PMID: 21455090. Full Text
  - Steg PG, Mehta S, Jolly S, Xavier D, Rupprecht H-J, Lopez-Sendon JL, Chrolavicius S, Rao SV, Granger CB, Pogue J, Laing S, Yusuf S. Fondaparinux with UnfracTionated heparin dUring Revascularization in Acute coronary syndromes (FUTURA/OASIS 8): a randomized trial of intravenous unfractionated heparin during percutaneous coronary intervention in patients with non-ST-segment elevation acute coronary syndromes initially treated with fondaparinux. American Heart Journal. 2010 Dec;160(6):1029-1034.e1. PubMed Central PMCID: 21146654. Full Text
  - Lopes RD, Li L, Granger CB, Wang TY, Foody JM, Funk M, Peterson ED, Alexander KP. Discharge Warfarin is Underused in High Risk Atrial Fibrillation Patients With Myocardial Infarction. CIRCULATION. 2010 Nov 23;122(21). Link to Item
  - Patel MR, Westerhout CM, Granger CB, Fu Y, Kim RJ, Armstrong PW. Aborted Myocardial Infarction after Primary PCI: Insights from Magnetic Resonance Imaging in the APEX-AMI Trial. CIRCULATION. 2010 Nov 23;122(21). Link to Item
  - Stewart AF, Dandona S, Fan M, Almontashiri N, Chen L, Davies RW, Wells GA, Tang W, Hazen SL, Ellix S, Reilley MP, Epstein S, Rader DJ, Engert JC, Anand S, Kathiresan S, Cupples AL, O'Donnell CJ, Shah S, Kraus WE, Granger CB, McPherson R, Roberts R. Identification of a Rare Variant Near Neurexin 1 Associated with Coronary Artery Disease. CIRCULATION. 2010 Nov 23;122(21). Link to Item
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  - Lopes RD, Mahaffey K, Harrington RA, Horton J, Armstrong P, Newby K, Ohman M, De Werf FV, Al-Khatib SM, Wallentin L, Granger CB. Atrial fibrillation is independently associated with a high risk of death in patients with acute coronary syndromes. CIRCULATION. 2007 Oct 16;116(16):315-315. Link to Item
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  - Chetcuti SJ, Silva S, Granger CB, Berger PB, Bates ER. The effect of infarct location in cardiogenic shock: The GUSTO experience. CIRCULATION. 1999 Nov 2;100(18):302-303. Link to Item
  - Goldmann BU, Ohman EM, Hamm CW, Bastos E, Newby K, Granger CB, Christenson RH, Califf RM. Is the adverse outcome with positive troponin T neutralized by revascularization? Results from GUSTO-IIa. CIRCULATION. 1999 Nov 2;100(18):810-810. Link to Item
  - Hudson MP, Granger CB, Stebbins AL, White HD, Bates ER, Greenbaum AB, Ohman EM. Cardiogenic shock survival and use of intraaortic balloon counterpulsation: Results from the GUSTO I and III trials. CIRCULATION. 1999 Nov 2;100(18):370-370. Link to Item
  - Mahaffey KW, Lee KL, White HD, Gore JM, Weaver WD, Granger CB, Califf RM, Sloan MA. Intracranial hemorrhage on the increase and beyond predicted levels: Serial results from two large thrombolysis trials. CIRCULATION. 1999 Nov 2;100(18):182-182. Link to Item
  - McGuire DK, Emanuelsson H, Charnwood A, Granger CB, White HD. Diabetes mellitus is associated with worse clinical outcomes across the spectrum of acute coronary syndromes: Results from GUSTO-IIb. CIRCULATION. 1999 Nov 2;100(18):432-432. Link to Item
  - Shah MR, Granger CB, Bart BA, McMurray JJ, Petrie MC, Tudor GE, Michelson EL, Stevenson LW, Califf RM, Pfeffer MA. Women are more likely to have adverse effects from angiotensin-converting enzyme inhibitors: Results from the SPICE registry. CIRCULATION. 1999 Nov 2;100(18):537-537. Link to Item
  - Cohen MG, Granger CB, Ohman EM, Stebbins AL, Grinfeld LR, Cagide AM, Elizari MV, Betriu A, Kong DF, Topol EJ, Califf RM. Outcome of Hispanic patients treated with thrombolytic therapy for acute myocardial infarction: results from the GUSTO-I and III trials. Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries. Journal of the American College of Cardiology. 1999 Nov;34(6):1729-1737. PubMed Central PMCID: 10577563. Full Text
  - Holmes DR, Berger PB, Hochman JS, Granger CB, Thompson TD, Califf RM, Vahanian A, Bates ER, Topol EJ. Cardiogenic shock in patients with acute ischemic syndromes with and without ST-segment elevation. Circulation. 1999 Nov;100(20):2067-2073. PubMed Central PMCID: 10562262. Full Text
  - Mahaffey KW, Puma JA, Barbagelata NA, DiCarli MF, Leesar MA, Browne KF, Eisenberg PR, Bolli R, Casas AC, Molina-Viamonte V, Orlandi C, Blevins R, Gibbons RJ, Califf RM, Granger CB. Adenosine as an adjunct to thrombolytic therapy for acute myocardial infarction: results of a multicenter, randomized, placebo-controlled trial: the Acute Myocardial Infarction STudy of ADenosine (AMISTAD) trial. Journal of the American College of Cardiology. 1999 Nov;34(6):1711-1720. PubMed Central PMCID: 10577561. Full Text
  - McGuire DK, Granger CB. Diabetes and ischemic heart disease. Am Heart J. 1999 Nov;138(5 Pt 1):S366-S375. PubMed PMID: 10539799. (Review) Link to Item
  - Mahaffey KW, Granger CB, Sloan MA, Green CL, Gore JM, Weaver W, White HD, Simoons ML, Barbash GI, Topol EJ, Califf RM. Neurosurgical evacuation of intracranial hemorrhage after thrombolytic therapy for acute myocardial infarction: Experience from the GUSTO-I Trial. American Heart Journal. 1999 Sep;138(3):493-499. Full Text
  - Mahaffey KW, Granger CB, Sloan MA, Green CL, Gore JM, Weaver WD, White HD, Simoons ML, Barbash GI, Topol EJ, Califf RM. Neurosurgical evacuation of intracranial hemorrhage after thrombolytic therapy for acute myocardial infarction: experience from the GUSTO-I trial. Global Utilization of Streptokinase and tissue-plasminogen activator (tPA) for Occluded Coronary Arteries. American Heart Journal. 1999 Sep;138(3 Pt 1):493-499. PubMed Central PMCID: 10467200. Full Text
  - Swedberg K, Pfeffer M, Granger C, Held P, McMurray J, Ohlin G, Olofsson B, Ostergren J, Yusuf S. Candesartan in heart failure--assessment of reduction in mortality and morbidity (CHARM): rationale and design. Charm-Programme Investigators. Journal of Cardiac Failure. 1999 Sep;5(3):276-282. PubMed Central PMCID: 10496201. Full Text
  - Assessment of the Safety and Efficacy of a New Thrombolytic (ASSENT-2) Investigators , Van De Werf F, Adgey J, Ardissino D, Armstrong PW, Aylward P, Barbash G, Betriu A, Binbrek AS, Califf R, Diaz R, Fanebust R, Fox K, Granger C, Heikkilä J, Husted S, Jansky P, Langer A, Lupi E, Maseri A, Meyer J, Mlczoch J, Mocceti D, Myburgh D, Oto A, Paolasso E, Pehrsson K, Seabra-Gomes R, Soares-Piegas L, Sùgrue D, Tendera M, Topol E, Toutouzas P, Vahanian A, Verheugt F, Wallentin L, White H. Single-bolus tenecteplase compared with front-loaded alteplase in acute myocardial infarction: the ASSENT-2 double-blind randomised trial. Lancet (London, England). 1999 Aug;354(9180):716-722. PubMed Central PMCID: 10475182. Full Text
  - Bart BA, Ertl G, Held P, Kuch J, Maggioni AP, McMurray J, Michelson EL, Rouleau JL, Warner Stevenson L, Swedberg K, Young JB, Yusuf S, Sellers MA, Granger CB, Califf RM, Pfeffer MA. Contemporary management of patients with left ventricular systolic dysfunction. Results from the Study of Patients Intolerant of Converting Enzyme Inhibitors (SPICE) Registry. European Heart Journal. 1999 Aug;20(16):1182-1190. PubMed Central PMCID: 10448027. Full Text
  - Batchelor WB, Peterson ED, Mark DB, Knight JD, Granger CB, Armstrong PW, Califf RM. A comparison of U.S. and Canadian cardiac catheterization practices in detecting severe coronary artery disease after myocardial infarction: efficiency, yield and long-term implications. Journal of the American College of Cardiology. 1999 Jul;34(1):12-19. PubMed Central PMCID: 10399985. Full Text
  - Berger PB, Ellis SG, Holmes DR, Granger CB, Criger DA, Betriu A, Topol EJ, Califf RM. Relationship between delay in performing direct coronary angioplasty and early clinical outcome in patients with acute myocardial infarction: results from the global use of strategies to open occluded arteries in Acute Coronary Syndromes (GUSTO-IIb) trial. Circulation. 1999 Jul;100(1):14-20. PubMed Central PMCID: 10393675. Full Text
  - Alexander JH, Granger CB, Sadowski Z, Aylward PE, White HD, Thompson TD, Califf RM, Topol EJ. Prophylactic lidocaine use in acute myocardial infarction: incidence and outcomes from two international trials. The GUSTO-I and GUSTO-IIb Investigators. American Heart Journal. 1999 May;137(5):799-805. PubMed Central PMCID: 10220627. Full Text
  - Alexander JH, Granger CB, Sadowski Z, Aylward PE, White HD, Thompson TD, Califf RM, Topol EJ. Prophylactic lidocaine use in acute myocardial infarction: Incidence and outcomes from two international trials. American Heart Journal. 1999 May;137(5):799-805. Full Text
  - Mahaffey KW, Harrington RA, Simoons ML, Granger CB, Graffagnino C, Alberts MJ, Laskowitz DT, Miller JM, Sloan MA, Berdan LG, MacAulay CM, Lincoff AM, Deckers J, Topol EJ, Califf RM. Stroke in patients with acute coronary syndromes: incidence and outcomes in the platelet glycoprotein IIb/IIIa in unstable angina. Receptor suppression using integrilin therapy (PURSUIT) trial. The PURSUIT Investigators. Circulation. 1999 May;99(18):2371-2377. PubMed Central PMCID: 10318656. Full Text
  - Sadowski ZP, Alexander JH, Skrabucha B, Dyduszynski A, Kuch J, Nartowicz E, Swiatecka G, Kong DF, Granger CB. Multicenter randomized trial and a systematic overview of lidocaine in acute myocardial infarction. Am Heart J. 1999 May;137(5):792-798. PubMed PMID: 10220626. Link to Item
  - Hasdai D, Lerman A, Rihal CS, Criger DA, Garratt KN, Betriu A, White HD, Topol EJ, Granger CB, Ellis SG, Califf RM, Holmes DR. Smoking status and outcome after primary coronary angioplasty for acute myocardial infarction. American Heart Journal. 1999 Apr;137(4 Pt 1):612-620. PubMed Central PMCID: 10097222. Full Text
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  - GRANGER CB, CALIFF RM. The GUSTO Trials. Journal of Interventional Cardiology. 1999 Feb;12(1):13-31. Full Text
  - Savonitto S, Ardissino D, Granger CB, Morando G, Prando MD, Mafrici A, Cavallini C, Melandri G, Thompson TD, Vahanian A, Ohman EM, Califf RM, Van de Werf F, Topol EJ. Prognostic value of the admission electrocardiogram in acute coronary syndromes. Jama. 1999 Feb;281(8):707-713. PubMed Central PMCID: 10052440. Full Text
  - Tung CY, Granger CB, Sloan MA, Topol EJ, Knight JD, Weaver WD, Mahaffey KW, White H, Clapp-Channing N, Simoons ML, Gore JM, Califf RM, Mark DB. Effects of Stroke on Medical Resource Use and Costs in Acute Myocardial Infarction. Circulation. 1999 Jan 26;99(3):370-376. Full Text
  - Barbagelata A, Di Carli MF, Sgarbossa EB, Califf RM, Clemmensen P, Criger DA, Gates KB, Gibbons RJ, Casabe H, Granger CB, Wagner GS, Mahaffey KW. The use of tomographic myocardial perfusion scanning to evaluate an electrocardiographic salvage estimation method in patients with acute myocardial infarction: an AMISTAD substudy. Acute Myocardial Infarction Study Adenosine. Journal of Electrocardiology. 1999 Jan;32 Suppl:111-113. PubMed Central PMCID: 10688313. Full Text
  - Barbagelata A, Di Carli MF, Sgarbossa EB, Califf RM, Clemmensen P, Criger DA, Gates KB, Gibbons RJ, Casabe H, Granger CB, Wagner GS, Mahaffey KW. The use of tomographic myocardial perfusion scanning to evaluate an electrocardiographic salvage estimation method in patients with acute myocardial infarction: An AMISTAD substudy. Journal of Electrocardiology. 1999 Jan;32:111-113. Full Text
  - Birnbaum Y, Wagner GS, Barbash GI, Gates K, Criger DA, Sclarovsky S, Siegel RJ, Granger CB, Reiner JS, Ross AM. Correlation of angiographic findings and right (V1 to V3) versus left (V4 to V6) precordial ST-segment depression in inferior wall acute myocardial infarction. The American Journal of Cardiology. 1999 Jan;83(2):143-148. PubMed Central PMCID: 10073811. Full Text
  - Hasdai D, Lerman A, Rihal CS, Criger DA, Garratt KN, Betriu A, White HD, Topol EJ, Granger CB, Ellis SG, Califf RM, Holmes J. Smoking status and outcome after primary coronary angioplasty for acute myocardial infarction. American Heart Journal. 1999 Jan 1;137(4 I):612-620. Full Text
  - Kleiman NS, Granger CB, White HD, Armstrong P, Ardissino D, Van de Werf F, Zoldeyhi P, Thompson TD, Califf RM, Topol EJ. Death and nonfatal reinfarction within the first 24 hours after presentation with an acute coronary syndrome: Experience from GUSTO-IIb. American Heart Journal. 1999 Jan;137(1):12-23. Full Text
  - Kleiman NS, Granger CB, White HD, Armstrong P, Ardissino D, de Werf FV, Zoldeyhi P, Thompson TD, Califf RM, Topol EJ. Death and nonfatal reinfarction within the first 24 hours after presentation with an acute coronary syndrome: experience from GUSTO-IIb. Global Utilization of Strategies for Total Occlusion. American Heart Journal. 1999 Jan;137(1):12-23. PubMed Central PMCID: 9878932. Full Text
  - Mahaffey KW, Toth CA, White HD, Stebbins AL, Granger CB, Chatterjee K. Thrombolytic therapy for acute MI in diabetics with retinopathy. Cardiology Review. 1999;16(11):27-32.
  - McGuire DK, Granger CB. Diabetes and ischemic heart disease. American Heart Journal. 1999;138(5 I):S366-S375. Full Text
  - O'Connor CM, Gattis WA, Gheorghiade M, Granger CB, Gilbert J, McKenney JM, Messineo FC, Burnett JC, Katz SD, Elkayam U, Kasper EK, Goldstein S, Cody RJ, Massie BM. A randomized trial of ecadotril versus placebo in patients with mild to moderate heart failure: The U.S. Ecadotril Pilot Safety Study. American Heart Journal. 1999;138(6 I):1140-1148.
  - Scirica BM, Moliterno DJ, Every NR, Anderson HV, Aguirre FV, Granger CB, Lambrew CT, Rabbani LE, Arnold A, Sapp SK, Booth JE, Ferguson JJ, Cannon CP. Differences between men and women in the management of unstable angina pectoris (the Guarantee Registry). American Journal of Cardiology. 1999;84(10):1145-1150. PubMed PMID: 10569321. Full Text
  - Scirica BM, Moliterno DJ, Every NR, Anderson HV, Aguirre FV, Granger CB, Lambrew CT, Rabbani LE, Sapp SK, Booth JE, Ferguson JJ, Cannon CP. Racial differences in the management of unstable angina: Results from the multicenter GUARANTEE registry. American Heart Journal. 1999;138(6 I):1065-1072.
  - Tung CY, Granger CB, Sloan MA, Topol EJ, Knight JD, Weaver WD, Mahaffey KW, White H, Clapp-Channing N, Simoons ML, Gore JM, Califf RM, Mark DB. Effects of stroke on medical resource use and costs in acute myocardial infarction. GUSTO I Investigators. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries Study. Circulation. 1999 Jan;99(3):370-376. PubMed Central PMCID: 9918523. Full Text
  - Alexander KP, Peterson ED, Granger CB, Casas A, Van de Werf F, Armstrong PW, Guerci A, Topol EJ, Califf RM. Potential impact of evidence-based medicine in acute coronary syndromes: insights from GUSTO-IIb. Journal of the American College of Cardiology. 1998 Dec;32(7):2023-2030. Full Text
  - Alexander KP, Peterson ED, Granger CB, Casas AC, Van de Werf F, Armstrong PW, Guerci A, Topol EJ, Califf RM. Potential impact of evidence-based medicine in acute coronary syndromes: insights from GUSTO-IIb. Global Use of Strategies to Open Occluded Arteries in Acute Coronary Syndromes trial. Journal of the American College of Cardiology. 1998 Dec;32(7):2023-2030. PubMed Central PMCID: 9857888. Full Text
  - Armstrong PW, Fu Y, Chang WC, Topol EJ, Granger CB, Betriu A, Van de Werf F, Lee KL, Califf RM. Acute coronary syndromes in the GUSTO-IIb trial: prognostic insights and impact of recurrent ischemia. The GUSTO-IIb Investigators. Circulation. 1998 Nov;98(18):1860-1868. PubMed Central PMCID: 9799205. Full Text
  - Newby LK, Christenson RH, Ohman EM, Armstrong PW, Thompson TD, Lee KL, Hamm CW, Katus HA, Cianciolo C, Granger CB, Topol EJ, Califf RM. Value of serial troponin T measures for early and late risk stratification in patients with acute coronary syndromes. The GUSTO-IIa Investigators. Circulation. 1998 Nov;98(18):1853-1859. PubMed Central PMCID: 9799204. Full Text
  - Zabel K, Granger CB, Becker RC, Bovill EG, Hirsh J, Aylward PE, Topol EJ, Califf RM. Use of bedside activated partial thromboplastin time monitor to adjust heparin dosing after thrombolysis for acute myocardial infarction: Results of GUSTO-I. American Heart Journal. 1998 Nov;136(5):868-876. Full Text
  - Zabel KM, Granger CB, Becker RC, Bovill EG, Hirsh J, Aylward PE, Topol EJ, Califf RM. Use of bedside activated partial thromboplastin time monitor to adjust heparin dosing after thrombolysis for acute myocardial infarction: results of GUSTO-I. Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries. American Heart Journal. 1998 Nov;136(5):868-876. PubMed Central PMCID: 9812083. Full Text
  - Armstrong PW, Fu YL, Chang WC, Granger CB, Betriu A, Van de Werf F, Lee KL. Acute coronary syndromes: Prognostic insights from GUSTO IIb. CIRCULATION. 1998 Oct 27;98(17):630-630. Link to Item
  - Armstrong PW, Fu YL, Chang WC, MacKenzie M, Mark DB, Granger CB, Califf RM. Canadian-American differences in management and outcome of non ST elevation acute coronary syndromes: 6 month follow up from the GUSTO IIb study. CIRCULATION. 1998 Oct 27;98(17):479-480. Link to Item
  - Batchelor WB, Peterson ED, Knight DJ, Armstrong PW, Granger CB. The use of a clinical predictive model for severe coronary artery disease improves the efficiency of cardiac catheterization in both the US and Canada. CIRCULATION. 1998 Oct 27;98(17):135-135. Link to Item
  - Di Carli MF, Barbagelata A, Mahaffey KW, Casas CA, Puma JA, Granger CB. Does preinfarction angina reduce infarct size? An ancillary study from the controlled, randomized AMISTAD trial. CIRCULATION. 1998 Oct 27;98(17):630-630. Link to Item
  - Fu YL, Armstrong PW, Chang WC, Ohman EM, Gupta M, Morris A, Roth SN, Granger CB, Califf RM, Mark DB. Impact of temporal trends in management on outcomes of acute myocardial infarction in Canada versus US. CIRCULATION. 1998 Oct 27;98(17):479-479. Link to Item
  - Miller JM, Ohman EM, Hasselblad V, Granger CB, Sketch MH, Kong DF, Califf RM. Can TIMI grade 3 flow at 60 minutes after thrombolysis substitute as a new angiographic standard? A meta-analytic approach. CIRCULATION. 1998 Oct 27;98(17):784-784. Link to Item
  - Roe MT, Bhatt DL, Houghtaling P, Granger CB. A three-fold subsequent risk of death or reinfarction among patients with creatine kinase elevation after percutaneous coronary intervention: Results of the GUSTO IIb study of acute coronary syndromes. CIRCULATION. 1998 Oct 27;98(17):496-496. Link to Item
  - Harrington RA, Kleiman NS, Granger CB, Ohman EM, Berkowitz SD. Relation between inhibition of platelet aggregation and clinical outcomes. Am Heart J. 1998 Oct;136(4 Pt 2 Su):S43-S50. PubMed PMID: 9778087. (Review) Link to Item
  - Sloan MA, Sila CA, Mahaffey KW, Granger CB, Longstreth WT, Koudstaal P, White HD, Gore JM, Simoons ML, Weaver WD, Green CL, Topol EJ, Califf RM. Prediction of 30-day mortality among patients with thrombolysis-related intracranial hemorrhage. Circulation. 1998 Oct;98(14):1376-1382. PubMed Central PMCID: 9760291. Full Text
  - Gebel JM, Sila CA, Sloan MA, Granger CB, Weisenberger JP, Green CL, Topol EJ, Mahaffey KW. Comparison of the ABC/2 estimation technique to computer-assisted volumetric analysis of intraparenchymal and subdural hematomas complicating the GUSTO-1 trial. Stroke. 1998 Sep;29(9):1799-1801. PubMed Central PMCID: 9731597. Full Text
  - Pfisterer M, Cox JL, Granger CB, Brener SJ, Naylor CD, Califf RM, van de Werf F, Stebbins AL, Lee KL, Topol EJ, Armstrong PW. Atenolol use and clinical outcomes after thrombolysis for acute myocardial infarction: the GUSTO-I experience. Global Utilization of Streptokinase and TPA (alteplase) for Occluded Coronary Arteries. Journal of the American College of Cardiology. 1998 Sep;32(3):634-640. PubMed Central PMCID: 9741504. Full Text
  - Granger CB. Heparin management in acute myocardial infarction (AMI). Aust N Z J Med. 1998 Aug;28(4):541-547. PubMed PMID: 9777136. Link to Item
  - Straznicky I, White HD, Granger CB, Aylward PE, Barbash GI, Topol EJ, Califf RM. Effects of four thrombolytic regimens in elderly patients. Cardiology Review. 1998 Jul 13;15(1):22-28.
  - Metz BK, White HD, Granger CB, Simes R, Armstrong PW, Hirsh J, Fuster V, MacAulay CM, Califf RM, Topol EJ. Randomized Comparison of Direct Thrombin Inhibition Versus Heparin in Conjunction With Fibrinolytic Therapy for Acute Myocardial Infarction: Results From the GUSTO-IIb Trial. Journal of the American College of Cardiology. 1998 Jun;31(7):1493-1498. Full Text
  - Metz BK, White HD, Granger CB, Simes RJ, Armstrong PW, Hirsh J, Fuster V, MacAulay CM, Califf RM, Topol EJ. Randomized comparison of direct thrombin inhibition versus heparin in conjunction with fibrinolytic therapy for acute myocardial infarction: results from the GUSTO-IIb Trial. Global Use of Strategies to Open Occluded Coronary Arteries in Acute Coronary Syndromes (GUSTO-IIb) Investigators. Journal of the American College of Cardiology. 1998 Jun;31(7):1493-1498. PubMed Central PMCID: 9626825. Full Text
  - Hochrein J, Sun F, Pieper KS, Lee KL, Gates KB, Armstrong PW, Weaver W, Goodman SG, Topol EJ, Califf RM, Granger CB, Wagner GS. Higher T-Wave Amplitude Associated With Better Prognosis in Patients Receiving Thrombolytic Therapy for Acute Myocardial Infarction (a GUSTO-I Substudy) 11This study was funded by grants from Bayer, New York, New York; CIBA-Corning, Medfield, Massachusetts; Genentech, South San Francisco, California; ICI Pharmaceuticals, Wilmington, Delaware; and Sanofi Pharmaceuticals, Paris, France. The American Journal of Cardiology. 1998 May;81(9):1078-1084. Full Text
  - Hochrein J, Sun F, Pieper KS, Lee KL, Gates KB, Armstrong PW, Weaver WD, Goodman SG, Topol EJ, Califf RM, Granger CB, Wagner GS. Higher T-wave amplitude associated with better prognosis in patients receiving thrombolytic therapy for acute myocardial infarction (a GUSTO-I substudy). Global Utilization of Streptokinase and Tissue plasminogen Activator for Occluded Coronary Arteries. The American Journal of Cardiology. 1998 May;81(9):1078-1084. PubMed Central PMCID: 9605045. Full Text
  - Califf RM, Granger CB. Hypertension and diabetes and the Fosinopril versus Amlodipine Cardiovascular Events Trial (FACET). More ammunition against surrogate end points. Diabetes Care. 1998 Apr;21(4):655-657. PubMed Central PMCID: 9571359. Full Text
  - Langer A, Krucoff MW, Klootwijk P, Simoons ML, Granger CB, Barr A, Califf RM, Armstrong PW. Prognostic significance of ST segment early after resolution ST elevation in patients with myocardial infarction treated with thrombolytic therapy: The GUSTO-I ST segment monitoring substudy. Journal of the American College of Cardiology. 1998 Mar 15;31(4):786-789.
  - Christenson RH, Duh SH, Newby LK, Ohman EM, Califf RM, Granger CB, Peck S, Pieper KS, Armstrong PW, Katus HA, Topol EJ. Cardiac troponin T and cardiac troponin I: relative values in short-term risk stratification of patients with acute coronary syndromes. GUSTO-IIa Investigators. Clinical Chemistry. 1998 Mar;44(3):494-501. PubMed Central PMCID: 9510853.
  - Esposito GA, Dunham G, Granger BB, Tudor GE, Granger CB. Converting i.v. nitroglycerin therapy to nitroglycerin ointment therapy: a comparison of two methods. Am J Crit Care. 1998 Mar;7(2):123-130. PubMed PMID: 9509226. Link to Item
  - Gebel JM, Sila CA, Sloan MA, Granger CB, Mahaffey KW, Weisenberger J, Green CL, White HD, Gore JM, Weaver WD, Califf RM, Topol EJ. Thrombolysis-related intracranial hemorrhage: a radiographic analysis of 244 cases from the GUSTO-1 trial with clinical correlation. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries. Stroke. 1998 Mar;29(3):563-569. PubMed Central PMCID: 9506593. Full Text
  - Gebel JM, Sila CA, Sloan MA, Granger CB, Mahaffey KW, Weisenberger J, Green CL, White HD, Gore JM, Weaver WD, Califf RM, Topol EJ. Thrombolysis-Related Intracranial Hemorrhage : A Radiographic Analysis of 244 Cases From the GUSTO-1 Trial With Clinical Correlation. Stroke. 1998 Mar 1;29(3):563-569. Full Text
  - Granger CB, Becker R, Tracy RP, Califf RM, Topol EJ, Pieper KS, Ross AM, Roth S, Lambrew C, Bovill EG. Thrombin generation, inhibition and clinical outcomes in patients with acute myocardial infarction treated with thrombolytic therapy and heparin: results from the GUSTO-I Trial. GUSTO-I Hemostasis Substudy Group. Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries. Journal of the American College of Cardiology. 1998 Mar;31(3):497-505. PubMed Central PMCID: 9502626. Full Text
  - Granger CB, Becker R, Tracy RP, Califf RM, Topol EJ, Pieper KS, Ross AM, Roth S, Lambrew C, Bovill EG. Thrombin Generation, Inhibition and Clinical Outcomes in Patients With Acute Myocardial Infarction Treated With Thrombolytic Therapy and Heparin: Results From the GUSTO-I Trial fn1fn1This study was supported by Genentech, Inc., South San Francisco, California; Bayer Corporation, New York, New York; CIBA-Corning, Medfield, Massachusetts; ICI Pharmaceuticals, Wilmington, Delaware; and Sanofi Pharmaceuticals, Paris, France. Journal of the American College of Cardiology. 1998 Mar;31(3):497-505. Full Text
  - Langer A, Krucoff MW, Klootwijk P, Simoons ML, Granger CB, Barr A, Califf RM, Armstrong PW. Prognostic significance of ST segment shift early after resolution of ST elevation in patients with myocardial infarction treated with thrombolytic therapy: the GUSTO-I ST Segment Monitoring Substudy. Journal of the American College of Cardiology. 1998 Mar;31(4):783-789. PubMed Central PMCID: 9525547. Full Text
  - Mahaffey KW, Granger CB, Sloan MA, Thompson TD, Gore JM, Weaver WD, White HD, Simoons ML, Barbash GI, Topol EJ, Califf RM. Risk factors for in-hospital nonhemorrhagic stroke in patients with acute myocardial infarction treated with thrombolysis: results from GUSTO-I. Circulation. 1998 Mar;97(8):757-764. PubMed Central PMCID: 9498539. Full Text
  - Hathaway WR. Prognostic Significance of the Initial Electrocardiogram in Patients With Acute Myocardial Infarction. Jama. 1998 Feb 4;279(5):387-387. Full Text
  - Califf RM, Abdelmeguid AE, Kuntz RE, Popma JJ, Davidson CJ, Cohen EA, Kleiman NS, Mahaffey KW, Topol EJ, Pepine CJ, Lipicky RJ, Granger CB, Harrington RA, Tardiff BE, Crenshaw BS, Bauman RP, Zuckerman BD, Chaitman BR, Bittl JA, Ohman EM. Myonecrosis after revascularization procedures. Journal of the American College of Cardiology. 1998 Feb;31(2):241-251. PubMed Central PMCID: 9462562. (Review) Full Text
  - Gilchrist IC, Granger CB, Thompson TD, Califf RM. Heparin dosing and outcome in acute coronary syndromes: The GUSTO-IIb experience. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 1998 Feb;31(2):78A-78A. Full Text Link to Item
  - Goodman SG, Langer A, Ross AM, Wildermann NM, Barbagelata A, Sgarbossa EB, Wagner GS, Granger CB, Califf RM, Topol EJ, Simoons ML, Armstrong PW. Non-Q-wave versus Q-wave myocardial infarction after thrombolytic therapy: angiographic and prognostic insights from the global utilization of streptokinase and tissue plasminogen activator for occluded coronary arteries-I angiographic substudy. GUSTO-I Angiographic Investigators. Circulation. 1998 Feb;97(5):444-450. PubMed Central PMCID: 9490238. Full Text
  - Granger CB, Van de Werf F, Armstrong PW, Simes J, White H, MacAulay CM, Califf RM, Topol EJ, Investigators GUTSTOI. Hirudin reduces death and myocardial (Re)infarction at 6-months: Follow-up results of the GUSTO IIb trial. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 1998 Feb;31(2):79A-79A. Full Text Link to Item
  - Hathaway WR, Peterson ED, Wagner GS, Granger CB, Zabel KM, Pieper KS, Clark KA, Woodlief LH, Califf RM. Prognostic significance of the initial electrocardiogram in patients with acute myocardial infarction. GUSTO-I Investigators. Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries. Jama. 1998 Feb;279(5):387-391. PubMed Central PMCID: 9459474. Full Text
  - Krucoff MW, Green CL, Trollinger KM, Granger CB, Ohman EM, O'Connor CM, Harrington RA, Armstrong PW, Simoons ML, Topol EJ, Califf RM. A comparison of static serial vs continuous ST-segment recovery to predict outcome after lytics for MI. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 1998 Feb;31(2):228A-229A. Full Text Link to Item
  - Mahaffey KW, Harrington RA, Graffagnino C, Alberts MJ, Sloan MA, Miller JM, Granger CB, Simoons ML, Topol EJ, Califf RM. Comparison of stroke rates in patients with acute coronary syndromes and patients with acute myocardial infarction. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 1998 Feb;31(2):406A-406A. Full Text Link to Item
  - Mahaffey KW, Tardiff BE, Granger CB, Lee KL, Harrington RA, Topol EJ, Califf RM. Disagreement between site investigators and clinical event committees is common and can affect trial results. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 1998 Feb;31(2):184A-185A. Full Text Link to Item
  - Ardissino D, Merlini PA, Eisenberg PR, Kottke-Marchant K, Crenshaw BS, Granger CB. Coagulation markers and outcomes in acute coronary syndromes. American Heart Journal. 1998;136(4 II SUPPL.):S7-S18. PubMed PMID: 9778084. Full Text
  - Every NR, Cannon CP, Granger C, Moliterno DJ, Aguirre FV, Talley JD, Booth J, Sapp S, Ferguson JJ. Influence of insurance type on the use of procedures, medications and hospital outcome in patients with unstable angina: Results from the GUARANTEE Registry. Journal of the American College of Cardiology. 1998;32(2):387-392. PubMed PMID: 9708465. Full Text
  - Harrington RA, Kleiman NS, Granger CB, Ohman EM, Berkowitz SD. Relation between inhibition of platelet aggregation and clinical outcomes. American Heart Journal. 1998;136(4 II SUPPL.):S43-S50. Full Text
  - Hirsh J, Warkentin TE, Raschke R, Granger C, Ohman EM, Dalen JE. Heparin and low-molecular-weight heparin: Mechanisms of action, Pharmacokinetics, dosing considerations, monitoring, efficacy, and safety. Chest. 1998;114(5 SUPPL.):489S-510S.
  - Mahaffey KW, Granger CB, Sloan MA. Assessing risk factors for nonhemorrhagic stroke after acute myocardial infarction. Cardiology Review. 1998;15(11):46-50.
  - Sgarbossa EB, Pinski SL, Topol EJ, Califf RM, Barbagelata A, Goodman SG, Gates KB, Granger CB, Miller DP, Underwood DA, Wagner GS. Acute myocardial infarction and complete bundle branch block at hospital admission: clinical characteristics and outcome in the thrombolytic era. GUSTO-I Investigators. Global Utilization of Streptokinase and t-PA [tissue-type plasminogen activator] for Occluded Coronary Arteries. Journal of the American College of Cardiology. 1998 Jan;31(1):105-110. PubMed Central PMCID: 9426026. Full Text
  - Mahaffey KW, Granger CB, Toth CA, White HD, Stebbins AL, Barbash GI, Vahanian A, Topol EJ, Califf RM. Diabetic retinopathy should not be a contraindication to thrombolytic therapy for acute myocardial infarction: review of ocular hemorrhage incidence and location in the GUSTO-I trial. Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries. J Am Coll Cardiol. 1997 Dec;30(7):1606-1610. PubMed PMID: 9385883. Link to Item
  - Mahaffey KW, Granger CB, Toth CA, White HD, Stebbins AL, Barbash GI, Vahanian A, Topol EJ, Califf RM. Diabetic retinopathy should not be a contraindication to thrombolytic therapy for acute myocardial infarction: review of ocular hemorrhage incidence and location in the GUSTO-I trial. Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries. Journal of the American College of Cardiology. 1997 Dec;30(7):1606-1610. PubMed Central PMCID: 9385883. Full Text
  - Aylward PE, Sadowski Z, Granger CB, Ardissino D, Wilcox RG, Armstrong PW, Card T, Hartford M, White HD. International differences in outcomes: Results from the GUSTO-III trial. CIRCULATION. 1997 Oct 21;96(8):1118-1118. Link to Item
  - Batchelor WB, Granger CB, Phillips HR, Kleinman NS, Stebbins AL. Ionic, low osmolar contrast is associated with better outcome following direct PTCA: Results from GUSTO-IIb. CIRCULATION. 1997 Oct 21;96(8):2978-2978. Link to Item
  - Cannon CP, Scirica BM, Every NR, Anderson HV, Aguirre FV, Granger CB, Lambrew CT, Rabbani LE, Sapp SK, Booth JE. Racial differences in the management of unstable angina: Results from the GUARANTEE registry. CIRCULATION. 1997 Oct 21;96(8):3329-3329. Link to Item
  - Granger CB, Betriu A, Phillips HR, Stebbins AL, Califf RM. Nearly half of early benefit of direct angioplasty lost in longer term follow-up: 6-month results from the GUSTO-IIb direct angioplasty substudy. CIRCULATION. 1997 Oct 21;96(8):1137-1137. Link to Item
  - Mahaffey KW, Puma JA, Barbagelata A, Casas CA, Lambe L, Orlandi C, Gibbons RJ, Califf RM, Granger CB. Does adenosine in conjunction with thrombolysis reduce infarct size? Results from the controlled, randomized AMISTAD trial. CIRCULATION. 1997 Oct 21;96(8):1144-1144. Link to Item
  - Miller JM, Phillips HR, Barness GW, Wildermann N, Betriu AB, Garcia EL, Aylward PE, Granger CB. TIMI grade 3 flow after primary coronary angioplasty predicts both early and late survival following acute myocardial infarction. CIRCULATION. 1997 Oct 21;96(8):2236-2236. Link to Item
  - Newby K, Harrington RA, Bhapkar M, Granger CB, Rames A, Moliterno D. Tight control of aPTT in acute coronary syndrome patients using an automated strategy for bedside heparin adjustment: Results from the PARAGON A trial. CIRCULATION. 1997 Oct 21;96(8):4200-4200. Link to Item
  - Berdan LG, Kleiman NS, Woodlief LH, Harrington RA, Granger CB, Califf RM. Physicians' use of heparin following thrombolytic therapy: An international perspective. Journal of Thrombosis and Thrombolysis. 1997 Sep 12;4(3-4):415-423. Full Text
  - Anderson RD, Ohman EM, Holmes DR, Col I, Stebbins AL, Bates ER, Stomel RJ, Granger CB, Topol EJ, Califf RM. Use of intraaortic balloon counterpulsation in patients presenting with cardiogenic shock: observations from the GUSTO-I Study. Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries. Journal of the American College of Cardiology. 1997 Sep;30(3):708-715. PubMed Central PMCID: 9283530. Full Text
  - Crenshaw BS, Ward SR, Granger CB, Stebbins AL, Topol EJ, Califf RM. Atrial fibrillation in the setting of acute myocardial infarction: the GUSTO-I experience. Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries. Journal of the American College of Cardiology. 1997 Aug;30(2):406-413. PubMed Central PMCID: 9247512. Full Text
  - Anderson R, Ohman E, Holmes DR, Col J, Stebbins AL, Bates ER, Stomel RJ, Granger CB, Topol EJ, Califf RM. Use of Intraaortic Balloon Counterpulsation in Patients Presenting With Cardiogenic Shock: Observations From the GUSTO-I Study fn1fn1This study was funded by grants from Bayer, New York, New York; CIBA-Corning, Medfield, Massachusetts; Genentech, South San Francisco, California; ICI Pharmaceuticals, Wilmington, Delaware; and Sanofi Pharmaceuticals, Paris, France. Journal of the American College of Cardiology. 1997 Jul;30(3):708-715. Full Text
  - Mak K-H, Moliterno DJ, Granger CB, Miller DP, White HD, Wilcox RG, Califf RM, Topol EJ. Influence of Diabetes Mellitus on Clinical Outcome in the Thrombolytic Era of Acute Myocardial Infarction fn1fn1The GUSTO-I study was supported by a combined grant from Bayer, New York, New York; CIBA-Corning, Medfield, Massachusetts; Genetech, South San Francisco, California; ICI Pharmaceuticals, Wilmington, Delaware; and Sanofi Pharmaceuticals, Paris, France. Journal of the American College of Cardiology. 1997 Jul;30(1):171-179. Full Text
  - Mak KH, Moliterno DJ, Granger CB, Miller DP, White HD, Wilcox RG, Califf RM, Topol EJ. Influence of diabetes mellitus on clinical outcome in the thrombolytic era of acute myocardial infarction. GUSTO-I Investigators. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries. Journal of the American College of Cardiology. 1997 Jul;30(1):171-179. PubMed Central PMCID: 9207639. Full Text
  - Migrino RQ, Young JB, Ellis SG, White HD, Lundergan CF, Miller DP, Granger CB, Ross AM, Califf RM, Topol EJ. End-systolic volume index at 90 to 180 minutes into reperfusion therapy for acute myocardial infarction is a strong predictor of early and late mortality. The Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries (GUSTO)-I Angiographic Investigators. Circulation. 1997 Jul;96(1):116-121. PubMed Central PMCID: 9236425. Full Text
  - Migrino RQ, Young JB, Ellis SG, White HD, Lundergan CF, Miller DP, Granger CB, Ross AM, Califf RM, Topol EJ. End-systolic volume index at 90 to 180 minutes into reperfusion therapy for acute myocardial infarction is a strong predictor of early and late mortality. Circulation. 1997 Jul 1;96(1):116-121. Full Text
  - Granger CB. Adenosine for myocardial protection in acute myocardial infarction. Am J Cardiol. 1997 Jun 19;79(12A):44-48. PubMed PMID: 9223363. (Review) Link to Item
  - Berkowitz SD, Granger CB, Pieper KS, Lee KL, Gore JM, Simoons M, Armstrong PW, Topol EJ, Califf RM. Incidence and Predictors of Bleeding After Contemporary Thrombolytic Therapy for Myocardial Infarction. Circulation. 1997 Jun 3;95(11):2508-2516. Full Text
  - Berkowitz SD, Granger CB, Pieper KS, Lee KL, Gore JM, Simoons M, Armstrong PW, Topol EJ, Califf RM. Incidence and predictors of bleeding after contemporary thrombolytic therapy for myocardial infarction. The Global Utilization of Streptokinase and Tissue Plasminogen activator for Occluded coronary arteries (GUSTO) I Investigators. Circulation. 1997 Jun;95(11):2508-2516. PubMed Central PMCID: 9184581. Full Text
  - Berkowitz SD, Granger CB, Pieper KS, Topol EJ, Califf RM. Incidence and predictors of bleeding after antithrombin therapy for acute coronary syndromes: The GUSTO II trials. THROMBOSIS AND HAEMOSTASIS. 1997 Jun:PS963-PS963. Link to Item
  - Berkowitz SD, Granger CB, Thompson T, Kleiman NS, Topol EJ, Califf RM. Thombocytopenia was associated with greater hemorrhage and higher mortality in GUSTO IIb trial. THROMBOSIS AND HAEMOSTASIS. 1997 Jun:PS962-PS962. Link to Item
  - Alberts MJ, Davis JP, Graffagnino C, McClenny C, Delong D, Granger C, Herbstreith MH, Boteva K, Marchuk DA, Roses AD. Endoglin gene polymorphism as a risk factor for sporadic intracerebral hemorrhage. Ann Neurol. 1997 May;41(5):683-686. PubMed PMID: 9153532. Full Text Link to Item
  - Califf RM, Lee KL, Granger CB, Ohman EM. Predictors of outcome of reperfusion therapy. European Heart Journal. 1997 May;18(5):728-735. PubMed Central PMCID: 9152643. (Review) Full Text
  - Jelesoff NE, Feinglos M, Granger CB, Califf RM. Outcomes of diabetic patients following acute myocardial infarction: a review of the major thrombolytic trials. Journal of Cardiovascular Risk. 1997 Apr;4(2):100-111. PubMed Central PMCID: 9304491. (Review)
  - Barbagelata A, Califf RM, Sgarbossa EB, Goodman SG, Stebbins AL, Granger CB, Suarez LD, Borruel M, Gates K, Starr S, Wagner GS. Thrombolysis and Q wave versus non-Q wave first acute myocardial infarction: a GUSTO-I substudy. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Arteries Investigators. Journal of the American College of Cardiology. 1997 Mar;29(4):770-777. PubMed Central PMCID: 9091523. Full Text
  - Barbagelata A, Califf RM, Sgarbossa EB, Goodman SG, Stebbins AL, Granger CB, Suarez LD, Borruel M, Gates K, Starr S, Wagner GS. Thrombolysis and Q Wave Versus Non-Q Wave First Acute Myocardial Infarction: A GUSTO-I Substudy. Journal of the American College of Cardiology. 1997 Mar;29(4):770-777. Full Text
  - Barbagelata NA, Granger CB, Oqueli E, Suárez LD, Borruel M, Topol EJ, Califf RM. TIMI grade 3 flow and reocclusion after intravenous thrombolytic therapy: a pooled analysis. American Heart Journal. 1997 Mar;133(3):273-282. PubMed Central PMCID: 9060794. Full Text
  - Alexander KP, Peterson ED, Hellkamp AS, Granger CB, Topol EJ, Califf RM. Early catheterization is standard strategy in unstable angina/NQWMI: Results from GUSTO IIb. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 1997 Feb;29(2):5614-5614. Link to Item
  - Alexander KP, Peterson ED, Mahaffey KW, Casas AC, Granger CB, VandeWerf F, Armstrong PW, Mark DB, Topol EJ, Califf RM. Medical interventions in unstable angina: Does international clinical practice match evidence-based guidelines?. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 1997 Feb;29(2):23138-23138. Link to Item
  - Amsterdam PB, Hafley GE, Harrington RA, Granger CB, Topol EJ, Califf RM. Is the ECG adequate to identify patients with left circumflex occlusion in acute coronary syndromes?. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 1997 Feb;29(2):78128-78128. Link to Item
  - Barbagelata A, Califf RM, Sgarbossa EB, Goodman S, Knight D, Mark DB, Granger CB, Benazzi MD, Calvo A, Gates K, Agranatti DA, Starr S, Song Q, Mautner B, Wagner GS. Mortality, morbidity, resource use and quality of life following Q- vs non-Q-wave infarction and thrombolytic therapy: A GUSTO-I substudy. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 1997 Feb;29(2):78106-78106. Link to Item
  - Granger CB, Phillips HR, Betriu A, Ellis SG, Weaver WD, Aylward P, Stebbins A, Lee KL, Califf RM, Topol EJ. Direct angioplasty may be less advantageous in patients presenting early after symptom onset: Results from GUSTO IIb. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 1997 Feb;29(2):7811-7811. Link to Item
  - Krucoff MW, Green CL, Troliinger KM, Pope JE, Harrington RA, Granger CB, Ohman EM, Neuhaus K, Topol EJ, Califf RM. Temporal distribution of important ECG information in patients with MI: When should you take the next ECG after lytics?. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 1997 Feb;29(2):9466-9466. Link to Item
  - Krucoff MW, Green CL, Trollinger KM, Pope JE, Granger CB, Ohman EM, Califf RM. ST-segment recovery parameters predictive of outcome in AMI: Variability with infarct artery location and implications for therapeutic targets. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 1997 Feb;29(2):3455-3455. Link to Item
  - Mahaffey KW, Granger CB, Tardiff BE, Woodlief L, Lee KL, Weaver WD, Topol EJ, Califf RM. Endpoint adjudication by a clinical events committee can impact the statistical outcome of a clinical trial: Results from GUSTO-IIb. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 1997 Feb;29(2):3339-3339. Link to Item
  - Vorchheimer DA, Baruch L, Deperalta ET, Guzman IC, Hayes RM, Hellkamp AS, Granger CB, Topol EJ, Califf RM. Weight adjusted antithrombotic regimens eliminate the nitroglycerin-antithrombotic interaction. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 1997 Feb;29(2):3453-3453. Link to Item
  - Berdan LG, Kleiman NS, Woodlief LH, Harrington RA, Granger CB, Califf RM. Physicians' Use of Heparin Following Thrombolytic Therapy: An International Perspective. Journal of Thrombosis and Thrombolysis. 1997 Jan;4(3/4):415-423. PubMed Central PMCID: 10639646. Full Text
  - Granger CB. Adenosine for myocardial protection in acute myocardial infarction. American Journal of Cardiology. 1997;79(12 A):44-48. Full Text
  - Aylward PE, Wilcox RG, Horgan JH, White HD, Granger CB, Califf RM, Topol EJ. Relation of increased arterial blood pressure to mortality and stroke in the context of contemporary thrombolytic therapy for acute myocardial infarction. A randomized trial. GUSTO-I Investigators. Annals of Internal Medicine. 1996 Dec;125(11):891-900. PubMed Central PMCID: 8967669. Full Text
  - Alexander JH, Granger CB, Thompson TD, Sadowski Z, Aylward PE. Prophylactic lidocaine use in GUSTO-I and GUSTO-II: Incidence and outcomes. CIRCULATION. 1996 Oct 15;94(8):1143-1143. Link to Item
  - Armstrong PW, Califf RM, Granger CB, Woodlief LH, Topol EJ. Recurrent ischemia in the GUSTO IIb trial. CIRCULATION. 1996 Oct 15;94(8):2225-2225. Link to Item
  - Armstrong PW, Granger CB, Knight D, Sutherland W, ClappChanning N, Hlatky M, Mark D. Temporal trends in the process of myocardial infarction management; Canadian/US GUSTO experience. CIRCULATION. 1996 Oct 15;94(8):158-158. Link to Item
  - Armstrong PW, Granger CB, Knight D, Sutherland W, ClappChanning N, Hlatky M, Mark D. Practice patterns and outcomes amongst non ST elevation patients with acute coronary syndromes. CIRCULATION. 1996 Oct 15;94(8):160-160. Link to Item
  - Granger CB, Woodlief LH. Lack of rebound recurrence of reinfarction after discontinuation of antithrombin therapy: Results from the GUSTO IIb trial. CIRCULATION. 1996 Oct 15;94(8):2516-2516. Link to Item
  - Mark DB, Granger CB, Ellis SG, Phillips HR, Knight D, DavidsonRay L, Topol EJ. Costs of direct angioplasty versus thrombolysis for acute myocardial infarction: Results from the GUSTO II randomized trial. CIRCULATION. 1996 Oct 15;94(8):973-973. Link to Item
  - Metz BK, Granger CB, White HD, Simes J, Topol EJ. Streptokinase and hirudin reduces death and reinfarction in acute myocardial infarction compared with streptokinase and heparin: Results from GUSTO IIb. CIRCULATION. 1996 Oct 15;94(8):2509-2509. Link to Item
  - Moliterno DJ, Aguirre FV, Cannon CP, Every NR, Granger CB, Sapp SK, Booth JE, Ferguson JJ. The global unstable angina registry and treatment evaluation (GUARANTEE) study. CIRCULATION. 1996 Oct 15;94(8):1136-1136. Link to Item
  - Simes RJ, Granger CB, Antman EM, Califf RM, Braunwald E, Topol EJ. Impact of hirudin versus heparin on mortality and (re)infarction in patients with acute coronary syndromes: A prospective meta-analysis of the GUSTO-IIb and TIMI 9b trials. CIRCULATION. 1996 Oct 15;94(8):2507-2507. Link to Item
  - Jelesoff NE, Feinglos M, Granger CB, Califf RM. Outcomes of diabetic patients following acute myocardial infarction: a review of the major thrombolytic trials. Coronary Artery Disease. 1996 Oct;7(10):732-743. PubMed Central PMCID: 8970764. (Review)
  - Ohman EM, Armstrong PW, Christenson RH, Granger CB, Katus HA, Hamm CW, O'Hanesian MA, Wagner GS, Kleiman NS, Harrell FE, Califf RM, Topol EJ. Cardiac troponin T levels for risk stratification in acute myocardial ischemia. GUSTO IIA Investigators. The New England Journal of Medicine. 1996 Oct;335(18):1333-1341. PubMed Central PMCID: 8857016. Full Text
  - White HD, Barbash GI, Califf RM, Simes RJ, Granger CB, Weaver WD, Kleiman NS, Aylward PE, Gore JM, Vahanian A, Lee KL, Ross AM, Topol EJ. Age and outcome with contemporary thrombolytic therapy. Results from the GUSTO-I trial. Global Utilization of Streptokinase and TPA for Occluded coronary arteries trial. Circulation. 1996 Oct;94(8):1826-1833. PubMed Central PMCID: 8873656. Full Text
  - Peterson ED, Hathaway WR, Zabel KM, Pieper KS, Granger CB, Wagner GS, Topol EJ, Bates ER, Simoons ML, Califf RM. Prognostic significance of precordial ST segment depression during inferior myocardial infarction in the thrombolytic era: results in 16,521 patients. Journal of the American College of Cardiology. 1996 Aug;28(2):305-312. PubMed Central PMCID: 8800102. Full Text
  - Granger CB, Miller JM, Bovill EG, Gruber A, Tracy RP, Krucoff MW, Green C, Berrios E, Harrington RA, Ohman EM, Califf RM. Rebound increase in thrombin generation and activity after cessation of intravenous heparin in patients with acute coronary syndromes. Journal of Intravenous Nursing. 1996 May 1;19(3):147-156.
  - Chang YC, Patz EF, Goodman PC, Granger CB. Significance of hemoptysis following thrombolytic therapy for acute myocardial infarction. Chest. 1996 Mar;109(3):727-729. PubMed PMID: 8617083. Link to Item
  - Granger CB, Hirsch J, Califf RM, Col J, White HD, Betriu A, Woodlief LH, Lee KL, Bovill EG, Simes RJ, Topol EJ. Activated partial thromboplastin time and outcome after thrombolytic therapy for acute myocardial infarction: results from the GUSTO-I trial. Circulation. 1996 Mar;93(5):870-878. PubMed Central PMCID: 8598077. Full Text
  - Mahaffey KW, Granger CB, Collins R, O'Connor CM, Ohman EM, Bleich SD, Col JJ, Califf RM. Overview of randomized trials of intravenous heparin in patients with acute myocardial infarction treated with thrombolytic therapy. The American Journal of Cardiology. 1996 Mar;77(8):551-556. PubMed Central PMCID: 8610601. Full Text
  - Granger CB. Diet and secondary prevention of coronary disease: Is it time to stop chewing the fat?. Journal of the American College of Cardiology. 1996;28(5):1109-1110. PubMed PMID: 8890802. Full Text
  - Sloan MA, Sila CA, Mahaffey KW, Granger CB, Longstreth WT, Green CL, Topol EJ. Clinical and radiographic factors associated with mortality following intracranial hemorrhage after thrombolysis for acute myocardial infarction. STROKE. 1996 Jan;27(1):90-90. Link to Item
  - Karnash SL, Granger CB, White HD, Woodlief LH, Topol EJ, Califf RM. Treating menstruating women with thrombolytic therapy: insights from the global utilization of streptokinase and tissue plasminogen activator for occluded coronary arteries (GUSTO-I) trial. Journal of the American College of Cardiology. 1995 Dec;26(7):1651-1656. PubMed Central PMCID: 7594099. Full Text
  - Barbagelata A, Granger CB, Topol EJ, Worley SJ, Kereiakes DJ, George BS, Ohman EM, Leimberger JD, Mark DB, Califf RM. Frequency, significance, and cost of recurrent ischemia after thrombolytic therapy for acute myocardial infarction. TAMI Study Group. The American Journal of Cardiology. 1995 Nov;76(14):1007-1013. PubMed Central PMCID: 7484852. Full Text
  - Gore JM, Granger CB, Simoons ML, Sloan MA, Weaver WD, White HD, Barbash GI, Van de Werf F, Aylward PE, Topol EJ. Stroke after thrombolysis. Mortality and functional outcomes in the GUSTO-I trial. Global Use of Strategies to Open Occluded Coronary Arteries. Circulation. 1995 Nov;92(10):2811-2818. PubMed Central PMCID: 7586246. Full Text
  - ANDERSON RD, STEBBINS AL, BATES E, STOMEL R, GRANGER CB, OHMAN EM. UNDERUTILIZATION OF AORTIC COUNTERPULSATION IN PATIENTS WITH CARDIOGENIC-SHOCK - OBSERVATIONS FROM THE GUSTO-1 STUDY. CIRCULATION. 1995 Oct 15;92(8):658-658. Link to Item
  - BERKOWITZ SD, GRANGER CB, PIEPER KS, CALIFF RM. HEMORRHAGIC NON-CNS COMPLICATIONS ASSOCIATED WITH 4 THROMBOLYTIC STRATEGIES FOR ACUTE MYOCARDIAL-INFARCTION. CIRCULATION. 1995 Oct 15;92(8):2197-2197. Link to Item
  - CRENSHAW BS, WARD SR, STEBBINS AL, GRANGER CB. RISK-FACTORS AND OUTCOMES IN PATIENTS WITH ATRIAL-FIBRILLATION FOLLOWING ACUTE MYOCARDIAL-INFARCTION. CIRCULATION. 1995 Oct 15;92(8):3740-3740. Link to Item
  - GOODMAN SG, LANGER A, WILDERMANN NM, BARBAGELATA A, SGARBOSSA EB, WAGNER GS, GRANGER CB, ROSS AM, ARMSTRONG PW. NON-Q VS Q-WAVE MYOCARDIAL-INFARCTION POST-THROMBOLYSIS - ANGIOGRAPHIC INSIGHTS. CIRCULATION. 1995 Oct 15;92(8):2529-2529. Link to Item
  - GRANGER CB, ARMSTRONG PW. REINFARCTION FOLLOWING DISCONTINUATION OF INTRAVENOUS HEPARIN OR HIRUDIN FOR UNSTABLE ANGINA AND ACUTE MYOCARDIAL-INFARCTION. CIRCULATION. 1995 Oct 15;92(8):2196-2196. Link to Item
  - GRANGER CB, CALIFF RM, VANDEWERF F, WHITE HD, TOPOL EJ. ACTIVATED PARTIAL THROMBOPLASTIN TIME AND CLINICAL OUTCOME AMONG PATIENTS WITH UNSTABLE ANGINA OR NON-Q-WAVE MI TREATED WITH INTRAVENOUS HEPARIN. CIRCULATION. 1995 Oct 15;92(8):1985-1985. Link to Item
  - MAHAFFEY KW, GRANGER CB, STEBBINS AL, CALIFF RM. DIABETIC-RETINOPATHY SHOULD NOT BE A CONTRAINDICATION TO THROMBOLYTIC THERAPY - QUANTIFICATION OF RISK IN 6011 PATIENTS. CIRCULATION. 1995 Oct 15;92(8):1986-1986. Link to Item
  - PETERSON ED, MARK DB, ARMSTRONG PW, KNIGHT D, GRANGER CB. DOES A CONSERVATIVE POST-MI CATHETERIZATION STRATEGY MISS SEVERE CORONARY-DISEASE - COMPARISONS OF USE AND DIAGNOSTIC YIELD IN CANADA AND THE US. CIRCULATION. 1995 Oct 15;92(8):565-565. Link to Item
  - TARDIFF BE, GRANGER CB, WOODLIEF L, MAHAFFEY KW, HARRINGTON RA, CALIFF RM. PROGNOSTIC-SIGNIFICANCE OF POST-INTERVENTION ISOZYME ELEVATIONS. CIRCULATION. 1995 Oct 15;92(8):2599-2599. Link to Item
  - Langer A, Krucoff MW, Klootwin P, Veldkamp R, Simoons ML, Granger C, Califf RM, Armstrong PW, GUSTO Investigators . Noninvasive assessment of speed and stability of infarct-related artery reperfusion: Results of the GUSTO ST segment monitoring study. Journal of the American College of Cardiology. 1995 Jun;25(7):1552-1557. Full Text
  - Pilote L, Granger C, Armstrong PW, Mark DB, Hlatky MA. Differences in the treatment of myocardial infarction between the United States and Canada. A survey of physicians in the GUSTO trial. Med Care. 1995 Jun;33(6):598-610. PubMed PMID: 7760576. Link to Item
  - Van de Werf F, Topol EJ, Lee KL, Woodlief LH, Granger CB, Armstrong PW, Barbash GI, Hampton JR, Guerci A, Simes RJ. Variations in patient management and outcomes for acute myocardial infarction in the United States and other countries. Results from the GUSTO trial. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries. Jama. 1995 May;273(20):1586-1591. PubMed Central PMCID: 7745771. Full Text
  - Granger CB, Miller JM, Bovill EG, Gruber A, Tracy RP, Krucoff MW, Green C, Berrios E, Harrington RA, Ohman EM. Rebound increase in thrombin generation and activity after cessation of intravenous heparin in patients with acute coronary syndromes. Circulation. 1995 Apr;91(7):1929-1935. PubMed Central PMCID: 7895349. Full Text
  - Granger CB, White HD, Bates ER, Ohman EM, Califf RM. A pooled analysis of coronary arterial patency and left ventricular function after intravenous thrombolysis for acute myocardial infarction. The American Journal of Cardiology. 1994 Dec;74(12):1220-1228. PubMed Central PMCID: 7977094. Full Text
  - KRUCOFF MW, GREEN CL, TROLLINGER KM, SAWCHAK ST, WILDERMAN NM, SHAH A, GRANGER CB, OCONNOR CM, POPE JE. UNIVARIATE RELATIONSHIPS BETWEEN MORTALITY AND PARAMETERS OF CONTINUOUS 12-LEAD ST-SEGMENT DEVIATION AND RECOVERY AFTER THROMBOLYTIC THERAPY FOR ACUTE INFARCTION. CIRCULATION. 1994 Oct;90(4):501-501. Link to Item
  - Mark DB, Naylor CD, Hlatky MA, Califf RM, Topol EJ, Granger CB, Knight JD, Nelson CL, Lee KL, Clapp-Channing NE. Use of medical resources and quality of life after acute myocardial infarction in Canada and the United States. The New England Journal of Medicine. 1994 Oct;331(17):1130-1135. PubMed Central PMCID: 7935638. Full Text
  - ZABEL KM, GRANGER CB, BECKER RC, WOODLIEF LH, CHESEBRO JH, CALIFF RM. BEDSIDE APTT MONITORING IS ASSOCIATED WITH LESS BLEEDING AMONG GUSTO PATIENTS RECEIVING IV HEPARIN FOLLOWING THROMBOLYTIC ADMINISTRATION. CIRCULATION. 1994 Oct;90(4):553-553. Link to Item
  - Califf RM, Granger CB. Trials of new antithrombin agents. Journal of Myocardial Ischemia. 1994 Aug 8;6(6):10-14.
  - Hillegass WB, Jollis JG, Granger CB, Ohman EM, Califf RM, Mark DB. Intracranial hemorrhage risk and new thrombolytic therapies in acute myocardial infarction. The American Journal of Cardiology. 1994 Mar;73(7):444-449. PubMed Central PMCID: 8141084. Full Text
  - MARK DB, NAYLOR CD, HLATKY MA, TOPOL EJ, KNIGHT JD, CLAPPCHANNING N, NELSON CL, CALIFF RM, GRANGER CB, ARMSTRONG PA. PATIENT SATISFACTION WITH HEALTH-CARE IS INSENSITIVE TO VARIATIONS IN CARE RECEIVED AND QUALITY-OF-LIFE - UNITED-STATES CANADA GUSTO SUBSTUDY RESULTS. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 1994 Feb:A166-A166. Link to Item
  - Krucoff MW, Green CL, Harrell FE, Simoons ML, Wilderman NM, Trollinger KM, Sawchak ST, Pope JE, Shah A, Granger CB. From signal/noise to information content/noise. Reconsidering the statistical analysis of continuous ST-segment data streams with gaps: potential optimization of application-specific information content using left, right, and interval censoring. Journal of Electrocardiology. 1994 Jan;27 Suppl:233-237. PubMed Central PMCID: 7884367. Full Text
  - Krucoff MW, Croll MA, Pope JE, Granger CB, O'Connor CM, Sigmon KN, Wagner BL, Ryan JA, Lee KL, Kereiakes DJ. Continuous 12-lead ST-segment recovery analysis in the TAMI 7 study. Performance of a noninvasive method for real-time detection of failed myocardial reperfusion. Circulation. 1993 Aug;88(2):437-446. PubMed Central PMCID: 8339407. Full Text
  - HILLEGASS WB, JOLLIS JG, GRANGER CB, CALIFF RM, MARK DB. HOW MANY LIVES DOES A NEW MORE POTENT THROMBOLYTIC AGENT HAVE TO SAVE TO JUSTIFY ADDITIONAL INTRACRANIAL HEMORRHAGES. CLINICAL RESEARCH. 1993 Apr;41(2):A122-A122. Link to Item
  - Granger CB, Califf RM, Young S, Candela R, Samaha J, Worley S, Kereiakes DJ, Topol EJ. Outcome of patients with diabetes mellitus and acute myocardial infarction treated with thrombolytic agents. The Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) Study Group. Journal of the American College of Cardiology. 1993 Mar;21(4):920-925. PubMed Central PMCID: 8450161. Full Text
  - Granger CB, Califf RM, Young S, Candela R, Samara J, Worley S, Kereiakes DJ, Topol EJ. Outcome of patients with diabetes mellitus and acute myocardial infarction treated with thrombolytic agents. Journal of the American College of Cardiology. 1993 Mar;21(4):920-925. Full Text
  - Krucoff MW, Croll MA, Pope JE, Pieper KS, Kanani PM, Granger CB, Veldkamp RF, Wagner BL, Sawchak ST, Califf RM. Continuously updated 12-lead ST-segment recovery analysis for myocardial infarct artery patency assessment and its correlation with multiple simultaneous early angiographic observations. The American Journal of Cardiology. 1993 Jan;71(2):145-151. PubMed Central PMCID: 8421974. Full Text
  - Krucoff MW, Green CL, Langer A, Klootwijk LJ, Trollinger KM, Sawchak ST, Wilderman NM, Veldkamp RF, Pope JE, Simoons ML. Global utilization of streptokinase and tPA for occluded arteries (GUSTO) ECG-monitoring substudy. Study design and technical considerations. J Electrocardiol. 1993;26 Suppl:249-255. PubMed PMID: 8189133. Link to Item
  - Ross AM, Lundergan C, Thompson M, Reiner J, Deychak Y, Rohrbeck S, Coyne K, Walker P, Cho S, Greenhouse S, al E. The effects of tissue plasminogen activator, streptokinase, or both on coronary-artery patency, ventricular function, and survival after acute myocardial infarction. New England Journal of Medicine. 1993;329(22):1615-1622. Full Text
  - GRANGER CB, CALIFF RM, HIRSH J, WOODLIEF LH, TOPOL EJ. APTTS AFTER THROMBOLYSIS AND STANDARD INTRAVENOUS HEPARIN ARE OFTEN LOW AND CORRELATE WITH BODY-WEIGHT, AGE AND SEX - EXPERIENCE FROM THE GUSTO TRIAL. CIRCULATION. 1992 Oct;86(4):258-258. Link to Item
  - GRANGER CB, OCONNOR CM, BLEICH SD, COL JJ, KEELER GP, OHMAN EM. AN OVERVIEW OF THE EFFECT OF INTRAVENOUS HEPARIN ON CLINICAL END-POINTS FOLLOWING THROMBOLYTIC THERAPY FOR ACUTE MYOCARDIAL-INFARCTION. CIRCULATION. 1992 Oct;86(4):259-259. Link to Item
  - GRANGER CB, OHMAN EM, BATES E. POOLED ANALYSIS OF ANGIOGRAPHIC PATENCY RATES FROM THROMBOLYTIC THERAPY TRIALS. CIRCULATION. 1992 Oct;86(4):269-269. Link to Item
  - KLINE EM, SMITH DD, MARTIN JS, DRACUP K, WOODLIEF LH, GRANGER CB, CALIFF RM. IN-HOSPITAL TREATMENT DELAYS IN PATIENTS TREATED WITH THROMBOLYTIC THERAPY - A REPORT OF THE GUSTO TIME TO TREATMENT SUBSTUDY. CIRCULATION. 1992 Oct;86(4):702-702. Link to Item
  - OHMAN EM, CHRISTENSON RH, GRANGER CB, BERRIOS E, WORLEY S, OCONNOR CM, SIGMON K, LEE K, PHILLIPS HR. NONINVASIVE DETECTION OF REPERFUSION AFTER THROMBOLYSIS BASED ON CLINICAL-ASSESSMENT AND RAPID CK-MB ANALYSIS. CIRCULATION. 1992 Oct;86(4):268-268. Link to Item
  - Granger CB, Califf RM, Topol EJ. Thrombolytic Therapy for Acute Myocardial Infarction : A Review. Drugs. 1992 Sep;44(3):293-325. PubMed PMID: 28634913. (Review) Full Text
  - Granger CB, Califf RM, Topol EJ. Thrombolytic therapy for acute myocardial infarction. A review . Drugs. 1992 Sep;44(3):293-325. PubMed Central PMCID: 1382931. (Review) Full Text
  - Granger CB, Gabriel DA, Reece NS, Boothroyd E, Harding MB, Harrison JK, Kong Y, Bashore TM. Fibrin modification by ionic and nonionic contrast media during cardiac catheterization. Am J Cardiol. 1992 Mar 15;69(8):821-823. PubMed PMID: 1546665. Link to Item
  - Califf RM, Granger C. TIMI IIB follow-up. Lessons for clinicians and investigators. Circulation. 1992 Feb;85(2):839-841. PubMed Central PMCID: 1735174. Full Text
  - KRUCOFF MW, CROLL MA, GRANGER CB, OCONNOR CM, SIGMON KN, POPE JE, WAUGH RA, KERIAKES DJ, GEORGE BS, SAMAHA JK, CALIFF RM. PROSPECTIVE BLINDED NONINVASIVE DETECTION OF FAILED THROMBOLYSIS USING DIGITAL TRENDING FROM CONTINUOUS 12-LEAD ST-SEGMENT MONITORING. CIRCULATION. 1990 Oct;82(4):254-254. Link to Item
  - GRANGER CB, GABRIEL DA, REECE NS, BOOTHROYD E, HARDING MB, HARRISON JK, KONG Y, BASHORE TM. FIBRIN MODIFICATION BY CONTRAST-MEDIA DURING CARDIAC-CATHETERIZATION. ARTERIOSCLEROSIS. 1990;10(5):A928-A928. Link to Item
  - Krucoff MW, Croll MA, Pope JE, Granger CB, Pieper KS, Sigmon KN, Lee KL, Califf RM. Heuristic and logistic principles of ST-segment interpretation in the time domain. Evolution in the context of the TAMI 7 trial design. Journal of Electrocardiology. 1990 Jan;23 Suppl:6-10. PubMed Central PMCID: 2128637. Full Text
  - Weissler AM, Miller BI, Granger CB, Henry TD, Sheikh KH, Kirch DL, Guess WB, Krumbach BJ. Augmentation of mortality risk discriminating power of left ventricular ejection fraction by measures of nonuniformity in systolic emptying on radionuclide ventriculography. Journal of the American College of Cardiology. 1990;16(2):387-395. PubMed PMID: 2373817.
  - Granger CB, Karimeddini MK, Smith V-E, Shapiro HR, Katz AM, Riba AL. Rapid ventricular filling in left ventricular hypertrophy: I. Physiologic hypertrophy. Journal of the American College of Cardiology. 1985;5(4):862-868. PubMed PMID: 3156175.
- Other Articles
  - Mehta RH, Honeycutt E, Peterson ED, Granger CB, Halabi AR, Shaw LK, Smith PK, Califf RM, Harrington RA, Sketch MH. Response to Letter Regarding Article, "Impact of Internal Mammary Artery Conduit on Long-Term Outcomes After Percutaneous Intervention of Saphenous Vein Graft". Circulation. 2006 Dec 19;114(25):e649-e649. Full Text

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